KR102488796B1 - 안구 건조증 치료 방법 - Google Patents
안구 건조증 치료 방법 Download PDFInfo
- Publication number
- KR102488796B1 KR102488796B1 KR1020197004640A KR20197004640A KR102488796B1 KR 102488796 B1 KR102488796 B1 KR 102488796B1 KR 1020197004640 A KR1020197004640 A KR 1020197004640A KR 20197004640 A KR20197004640 A KR 20197004640A KR 102488796 B1 KR102488796 B1 KR 102488796B1
- Authority
- KR
- South Korea
- Prior art keywords
- composition
- eye
- subject
- tear film
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662363565P | 2016-07-18 | 2016-07-18 | |
| US201662363592P | 2016-07-18 | 2016-07-18 | |
| US62/363,592 | 2016-07-18 | ||
| US62/363,565 | 2016-07-18 | ||
| US201662436727P | 2016-12-20 | 2016-12-20 | |
| US62/436,727 | 2016-12-20 | ||
| PCT/US2017/042382 WO2018017479A1 (en) | 2016-07-18 | 2017-07-17 | Methods of treating dry eye syndrome |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20190031280A KR20190031280A (ko) | 2019-03-25 |
| KR102488796B1 true KR102488796B1 (ko) | 2023-01-13 |
Family
ID=60992530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197004640A Active KR102488796B1 (ko) | 2016-07-18 | 2017-07-17 | 안구 건조증 치료 방법 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10960051B2 (enExample) |
| EP (1) | EP3484497A4 (enExample) |
| JP (1) | JP6889771B2 (enExample) |
| KR (1) | KR102488796B1 (enExample) |
| CN (1) | CN109789182A (enExample) |
| AU (1) | AU2017300268B2 (enExample) |
| CA (1) | CA3031069A1 (enExample) |
| WO (1) | WO2018017479A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022102757A (ja) * | 2020-12-25 | 2022-07-07 | ライオン株式会社 | 機械学習実行プログラム、ドライアイ検査プログラム、機械学習実行装置及びドライアイ検査装置 |
| JP7570229B2 (ja) * | 2020-12-25 | 2024-10-21 | ライオン株式会社 | 機械学習実行プログラム、ドライアイ検査プログラム、機械学習実行装置及びドライアイ検査装置 |
| JP7570228B2 (ja) * | 2020-12-25 | 2024-10-21 | ライオン株式会社 | 機械学習実行プログラム、ドライアイ検査プログラム、機械学習実行装置及びドライアイ検査装置 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080096817A1 (en) * | 1998-07-30 | 2008-04-24 | Regenerx Biopharmaceuticals, Inc. | METHODS OF TREATING DISORDERS OF THE EYE AND SURROUNDING TISSUE WITH THYMOSIN BETA 4 (Tbeta4), ANALOGUES, ISOFORMS AND OTHER DERIVATIVES |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991012808A1 (en) | 1990-02-22 | 1991-09-05 | Macnaught Pty Limited | Artificial tears |
| CN101195025A (zh) * | 2001-03-15 | 2008-06-11 | 雷金纳克斯生物制药公司 | 胸腺素β4、类似物、异构体及其它衍生物在制备治疗眼睛和周围组织失调的药物中的应用 |
| CA2458883C (en) * | 2001-08-29 | 2017-11-28 | Regenerx Biopharmaceuticals, Inc. | Methods of healing or preventing inflammation, damage and other changes that occur prior to, during or immediately after a myocardial event with thymosin beta 4, analogues, isoforms and other derivatives |
| JP2008526986A (ja) * | 2005-01-13 | 2008-07-24 | リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド | 神経変性疾患、筋変性疾患または神経筋変性疾患による組織の変敗、傷害または損傷の治療方法または予防の方法あるいは前記疾患によって悪影響を受ける組織の修復方法 |
| CN101198344A (zh) * | 2005-06-17 | 2008-06-11 | 雷金纳克斯生物制药公司 | 冻干的或可冻干形式的lkktet和/或lkktnt肽组合物 |
| KR20080033939A (ko) * | 2005-06-17 | 2008-04-17 | 리지너크스 바이오 파마소티컬스, 인코포레이티드 | 동결 건조된 형태이거나, 또는 동결 건조될 수 있는 형태인엘케이케이티이티 및/또는 엘케이케이티엔티 펩티드조성물들 |
| CN101152568A (zh) * | 2006-09-25 | 2008-04-02 | 宝勒日 | 具有促进血管形成、组织再生及伤口愈合作用的多肽组合制剂 |
| CN101743009A (zh) * | 2007-07-11 | 2010-06-16 | 辉瑞大药厂 | 治疗干眼病的药物组合物和方法 |
-
2017
- 2017-07-17 CN CN201780056154.4A patent/CN109789182A/zh active Pending
- 2017-07-17 AU AU2017300268A patent/AU2017300268B2/en active Active
- 2017-07-17 WO PCT/US2017/042382 patent/WO2018017479A1/en not_active Ceased
- 2017-07-17 US US16/318,571 patent/US10960051B2/en active Active
- 2017-07-17 KR KR1020197004640A patent/KR102488796B1/ko active Active
- 2017-07-17 EP EP17831632.9A patent/EP3484497A4/en not_active Withdrawn
- 2017-07-17 JP JP2019503485A patent/JP6889771B2/ja active Active
- 2017-07-17 CA CA3031069A patent/CA3031069A1/en active Pending
-
2021
- 2021-02-25 US US17/185,583 patent/US20210213103A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080096817A1 (en) * | 1998-07-30 | 2008-04-24 | Regenerx Biopharmaceuticals, Inc. | METHODS OF TREATING DISORDERS OF THE EYE AND SURROUNDING TISSUE WITH THYMOSIN BETA 4 (Tbeta4), ANALOGUES, ISOFORMS AND OTHER DERIVATIVES |
Also Published As
| Publication number | Publication date |
|---|---|
| US10960051B2 (en) | 2021-03-30 |
| US20190240294A1 (en) | 2019-08-08 |
| JP6889771B2 (ja) | 2021-06-18 |
| CN109789182A (zh) | 2019-05-21 |
| AU2017300268A1 (en) | 2019-01-31 |
| EP3484497A4 (en) | 2020-01-01 |
| JP2019525923A (ja) | 2019-09-12 |
| AU2017300268B2 (en) | 2024-06-13 |
| CA3031069A1 (en) | 2018-01-25 |
| KR20190031280A (ko) | 2019-03-25 |
| EP3484497A1 (en) | 2019-05-22 |
| WO2018017479A1 (en) | 2018-01-25 |
| US20210213103A1 (en) | 2021-07-15 |
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| Kumagami et al. | Comparison of Corneal Safety and Intraocular Pressure–Lowering Effect of Tafluprost Ophthalmic Solution with Other Prostaglandin Ophthalmic Solutions | |
| Tu et al. | Dry eye | |
| EP3338792A1 (en) | Corneal damage prevention/treatment composition comprising thymosin beta 4 and citric acid as active ingredients | |
| HK40012612A (en) | Methods of treating dry eye syndrome | |
| AU2023300970A1 (en) | Stable peptide compositions and methods of use thereof for treatment of moderate/severe dry eye-related ocular symptoms | |
| HK1256177A1 (en) | Lkktet and/or lkktnt peptide compositions which are lyophilized or in a form capable of being lyophilized | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| R15-X000 | Change to inventor requested |
St.27 status event code: A-3-3-R10-R15-oth-X000 |
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| R16-X000 | Change to inventor recorded |
St.27 status event code: A-3-3-R10-R16-oth-X000 |
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| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
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| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
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| E13-X000 | Pre-grant limitation requested |
St.27 status event code: A-2-3-E10-E13-lim-X000 |
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| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| PE0902 | Notice of grounds for rejection |
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St.27 status event code: A-2-3-E10-E13-lim-X000 |
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| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
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| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
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| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
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| PR1002 | Payment of registration fee |
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| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
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| R17-X000 | Change to representative recorded |
St.27 status event code: A-5-5-R10-R17-oth-X000 |
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| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
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