CN109758565B - Traditional Chinese medicine composition for externally treating spleen-stomach deficiency-cold type chronic gastritis by acupoint application and application thereof - Google Patents

Traditional Chinese medicine composition for externally treating spleen-stomach deficiency-cold type chronic gastritis by acupoint application and application thereof Download PDF

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CN109758565B
CN109758565B CN201910130601.7A CN201910130601A CN109758565B CN 109758565 B CN109758565 B CN 109758565B CN 201910130601 A CN201910130601 A CN 201910130601A CN 109758565 B CN109758565 B CN 109758565B
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chronic gastritis
spleen
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刘晏
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SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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Abstract

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for externally treating spleen-stomach deficiency-cold type chronic gastritis by acupoint application and application thereof. Taking 7-11 parts of rhizoma atractylodis, 7-11 parts of wrinkled gianthyssop herb, 10-14 parts of costus root, 10-14 parts of common fennel fruit, 10-14 parts of prepared nutgrass galingale rhizome, 7-11 parts of common fenugreek seed and 4-8 parts of dried ginger; grinding the above materials into powder, adding liquid matrix, concocting to obtain ointment, and fixing the ointment on patch material to obtain acupoint patch. The invention is suitable for patients with spleen-stomach deficiency-cold type chronic gastritis of different courses and different ages. Aiming at treating the spleen-stomach deficiency-cold type chronic gastritis, an external treatment method of applying medicines to acupuncture points is innovatively used, the treatment course is shortened to a great extent, the treatment means is convenient and effective, and the disease is initiated in the medical system of the quiet area in Shanghai city. The medicine used for external application follows the thought of 'spleen being suitable for warm transportation'; the selection of acupoints follows the principle of combining distant and near treatments and back transport and alarm, and enhances the actions of regulating qi, dredging collaterals, warming, transporting and removing blood stasis.

Description

Traditional Chinese medicine composition for externally treating spleen-stomach deficiency-cold type chronic gastritis by acupoint application and application thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for externally treating spleen-stomach deficiency-cold type chronic gastritis by acupoint application and application thereof.
Background
The chronic gastritis is a common disease which is various chronic gastric mucositis lesions caused by different causes, and the epidemiological investigation of the incidence of the chronic gastritis in various gastric diseases indicates that the disease is relatively high in east Asia, east Europe, south America and the like, the annual canceration rate of the chronic gastritis is about 2.55-7.46 percent, and the gastric cancer is the first malignant tumor in China at present. Therefore, the traditional Chinese medicine composition can effectively and quickly treat chronic atrophic gastritis and is an effective means for preventing the chronic atrophic gastritis from developing into gastric cancer so as to reduce the incidence rate of the gastric cancer. Since the fiberscope is widely applied, the diagnosis rate of the disease is obviously improved, and especially, the disease is suitable for precancerous lesions such as chronic atrophic gastritis in chronic gastritis. In the aspect of treatment, no specific treatment for treating the disease exists in western medicine at present, and asymptomatic patients are generally advocated to change living habits and adjust dietary structures; and (3) administering drug treatment to the patient with the symptom according to the test result, wherein the drug treatment comprises antibacterial drugs for eradicating helicobacter pylori, acid inhibitors, gastric mucosa protective agents, gastric motility promoting drugs and the like. Although the traditional Chinese medicine has a certain curative effect in clinic, the disease condition of the patient is easy to repeat due to stimulation of bad dietary habits, and long-term irregular administration also causes the patient to generate dependence and drug resistance on the medicine, and has certain toxic and side effects, so that the patient cannot be cured due to prolonged course of disease, and a better treatment scheme is required to be actively sought. The spleen-stomach deficiency-cold syndrome is one of the categories of the diseases in traditional Chinese medicine, and meanwhile, the traditional Chinese medicine has certain advantages in treating various types of chronic gastritis, and at present, the traditional Chinese medicine is mainly taken orally. The method has the disadvantages of long treatment period, high cost and inconvenient flow.
The prior art discloses a plurality of traditional Chinese medicine compositions for treating chronic gastritis by external application, for example, Chinese patent CN201510920827.9, discloses an acupoint application medicine for treating chronic atrophic gastritis, and the medicine is mainly prepared by mixing ginger, vaseline, frankincense, myrrh and pericarpium zanthoxyli; the weight percentage of the ginger is 72.73 percent, the vaseline is 21.82 percent, the frankincense is 1.36 percent, the myrrh is 1.36 percent, and the pericarpium zanthoxyli is 2.73 percent; can be used for treating chronic atrophic gastritis. A study on a study paper published in 2017 of Nanjing university of traditional Chinese medicine, "observation of clinical efficacy of warming stomach to paste acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis", discloses a traditional Chinese medicine prescription of warming stomach to paste acupoint application: is prepared from processed radix Aconiti lateralis, radix Aconiti lateralis Preparata, radix Et rhizoma Nardostachyos, rhizoma Typhonii, rhizoma corydalis, semen Sinapis, cortex Cinnamomi, herba asari, fructus Zanthoxyli, fructus Piperis Longi, fructus evodiae, and rhizoma Zingiberis. However, the difference between the prior art and the formula of the traditional Chinese medicine composition is large, and no report is found in the prior art about the traditional Chinese medicine composition for externally treating the spleen-stomach deficiency-cold type chronic gastritis by applying acupuncture points.
Disclosure of Invention
The first purpose of the invention is to provide an acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis, aiming at the defects in the prior art.
The second purpose of the invention is to provide a traditional Chinese medicine composition for externally treating spleen-stomach deficiency-cold type chronic gastritis by applying acupuncture points.
The third purpose of the present invention is to overcome the shortcomings of the prior art, and the purpose of the traditional Chinese medicine composition is as described above.
In order to achieve the first purpose, the invention adopts the technical scheme that:
an acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis is prepared by the following method: taking 7-11 parts of rhizoma atractylodis, 7-11 parts of wrinkled gianthyssop herb, 10-14 parts of costus root, 10-14 parts of common fennel fruit, 10-14 parts of prepared nutgrass galingale rhizome, 7-11 parts of common fenugreek seed and 4-8 parts of dried ginger; grinding the above materials into powder, adding liquid matrix, concocting to obtain ointment, and fixing the ointment on patch material to obtain acupoint patch.
In the above acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis, as a preferred scheme, the acupoint application is prepared by the following method: taking 8-10 parts of rhizoma atractylodis, 8-10 parts of agastache rugosus, 11-13 parts of costus root, 11-13 parts of fennel, 11-13 parts of prepared rhizoma cyperi, 8-10 parts of fenugreek and 5-7 parts of dried ginger; grinding the above materials into powder, adding liquid matrix, concocting to obtain ointment, and fixing the ointment on patch material to obtain acupoint patch.
In the above acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis, as a preferred scheme, the acupoint application is prepared by the following method: taking 9 parts of rhizoma atractylodis, 9 parts of agastache rugosus, 12 parts of costus root, 12 parts of fennel, 12 parts of prepared rhizoma cyperi, 9 parts of fenugreek and 6 parts of dried ginger; grinding the above materials into powder, adding liquid matrix, concocting to obtain ointment, and fixing the ointment on patch material to obtain acupoint patch.
In the above acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis, as a preferred scheme, the liquid matrix is mature vinegar, and the dosage of the mature vinegar is as follows: adding 5-20ml of mature vinegar into 3g of the medicinal powder for blending.
In the above acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis, as a preferred scheme, the acupoints are Pishu, Zhongwan, Zusanli and Guanyuan.
In order to achieve the second object, the invention adopts the technical scheme that:
a traditional Chinese medicine composition for treating spleen-stomach deficiency-cold type chronic gastritis by acupoint application is prepared from the following raw material medicines in parts by weight: 7-11 parts of rhizoma atractylodis, 7-11 parts of agastache rugosus, 10-14 parts of costus root, 10-14 parts of fennel, 10-14 parts of prepared rhizoma cyperi, 7-11 parts of fenugreek and 4-8 parts of dried ginger.
In the traditional Chinese medicine composition for treating spleen-stomach deficiency-cold type chronic gastritis by applying to acupuncture points and externally treating the spleen-stomach deficiency-cold type chronic gastritis, as a preferred scheme, the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 8-10 parts of rhizoma atractylodis, 8-10 parts of agastache rugosus, 11-13 parts of costus root, 11-13 parts of fennel, 11-13 parts of prepared rhizoma cyperi, 8-10 parts of fenugreek and 5-7 parts of dried ginger.
In the traditional Chinese medicine composition for treating spleen-stomach deficiency-cold type chronic gastritis by applying to acupuncture points and externally treating the spleen-stomach deficiency-cold type chronic gastritis, as a preferred scheme, the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 9 parts of rhizoma atractylodis, 9 parts of agastache rugosus, 12 parts of costus root, 12 parts of fennel, 12 parts of prepared rhizoma cyperi, 9 parts of fenugreek and 6 parts of dried ginger.
In order to achieve the third object, the invention adopts the technical scheme that:
the application of the traditional Chinese medicine composition in preparing the medicine for treating the spleen-stomach deficiency-cold type chronic gastritis is characterized in that the medicine is applied to acupuncture points, and the acupuncture points are Pishu, Zhongwan, Zusanli and Guanyuan.
The traditional Chinese medicine composition is obtained by continuous comparative screening and optimization of an inventor in clinical application, wherein the rhizoma atractylodis and the agastache rugosus are used as monarch drugs in the formula, and the effects of strengthening spleen, assisting transportation and warming and resolving phlegm-dampness are achieved; the costus root, the fennel and the prepared rhizoma cyperi are used together to regulate triple warmer qi, and promote qi circulation, relieve pain and dispel cold as the ministerial drugs; in the formula, the kidney is stomach-closed and opens into two yin, and the common fenugreek seed in the formula for dispelling cold and warming the kidney is used as an adjuvant; a little gan Jiang can strengthen the action of warming the middle energizer to dispel cold, so it is not too pungent to hurt the skin after being applied).
The invention has the advantages that:
1. the invention can effectively treat the spleen and stomach deficiency-cold type chronic gastritis by acupoint application, can obviously and quickly improve clinical symptoms and hyperemia, edema and erosion of gastric mucosa, is beneficial to the repair of atrophy and intestinal glandular metaplasia mucosa, shortens the course of treatment, makes up the vacancy of partial western medicine for treating the disease, and has wide market development prospect.
2. Quality control is convenient to grasp, the operation flow is standard, the clinical safety is higher, certain help is provided for improving the diagnosis and treatment standard of the disease, and the clinical special advantages are easy to form. Meanwhile, the invention is convenient and fast to apply and treat, is noninvasive and painless to operate, has strong patient acceptance and better curative effect, thereby not only saving medical insurance cost and bringing economic benefit, but also relieving the pain of patients, saving energy, promoting comprehensive utilization of resources and bringing social benefit.
3. The invention is suitable for patients with spleen-stomach deficiency-cold type chronic gastritis of different courses and different ages. The treatment method aims at treating the spleen-stomach deficiency-cold type chronic gastritis, creatively uses an external treatment method of medicine acupoint application, shortens the treatment course to a great extent, is convenient and effective in treatment means, and is the first initiative of the disease in the medical system of the quiet areas in Shanghai city. The medicine used for external application follows the thought of 'spleen being suitable for warm transportation'; the selection of acupoints follows the principle of combining distant and near treatments and back transport and alarm, and enhances the actions of regulating qi, dredging collaterals, warming, transporting and removing blood stasis.
Detailed Description
The invention will be further illustrated with reference to specific embodiments. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that various changes and modifications can be made by those skilled in the art after reading the disclosure of the present invention, and equivalents fall within the scope of the appended claims.
Example 1A Chinese medicinal composition for treating chronic gastritis due to deficiency-cold of spleen and stomach by applying to acupuncture points
Taking the traditional Chinese medicine composition: 9 parts of rhizoma atractylodis, 9 parts of agastache rugosus, 12 parts of costus root, 12 parts of fennel, 12 parts of prepared rhizoma cyperi, 9 parts of fenugreek and 6 parts of dried ginger.
Example 2A Chinese medicinal composition for treating chronic gastritis due to deficiency-cold of spleen and stomach by applying to acupuncture points
Taking the traditional Chinese medicine composition: 7 parts of rhizoma atractylodis, 7 parts of agastache rugosus, 10 parts of costus root, 10 parts of fennel, 14 parts of prepared rhizoma cyperi, 11 parts of fenugreek and 8 parts of dried ginger.
Example 3A Chinese medicinal composition for treating chronic gastritis due to deficiency-cold of spleen and stomach by applying to acupuncture points
Taking the traditional Chinese medicine composition: 11 parts of rhizoma atractylodis, 11 parts of agastache rugosus, 14 parts of costus root, 14 parts of fennel, 10 parts of prepared rhizoma cyperi, 7 parts of fenugreek and 4 parts of dried ginger.
Example 4 Chinese medicinal composition for external treatment of spleen-stomach deficiency-cold type chronic gastritis by acupoint application
Taking the traditional Chinese medicine composition: 7 parts of rhizoma atractylodis, 11 parts of agastache rugosus, 10 parts of costus root, 14 parts of fennel, 10 parts of prepared rhizoma cyperi, 11 parts of fenugreek and 4 parts of dried ginger.
Example 5 Chinese medicinal composition for external treatment of spleen-stomach deficiency-cold type chronic gastritis by acupoint application
Taking the traditional Chinese medicine composition: 11 parts of rhizoma atractylodis, 7 parts of agastache rugosus, 14 parts of costus root, 10 parts of fennel, 14 parts of prepared rhizoma cyperi, 7 parts of fenugreek and 8 parts of dried ginger.
Example 6 Chinese medicinal composition for external treatment of spleen-stomach deficiency-cold type chronic gastritis by acupoint application
Taking the traditional Chinese medicine composition: 7 parts of rhizoma atractylodis, 7 parts of agastache rugosus, 14 parts of costus root, 14 parts of fennel, 10 parts of prepared rhizoma cyperi, 7 parts of fenugreek and 8 parts of dried ginger.
Example 7 Chinese medicinal composition (VII) for treating spleen-stomach deficiency-cold type chronic gastritis by applying to acupuncture points
Taking the traditional Chinese medicine composition: 11 parts of rhizoma atractylodis, 11 parts of agastache rugosus, 10 parts of costus root, 10 parts of fennel, 14 parts of prepared rhizoma cyperi, 11 parts of fenugreek and 4 parts of dried ginger.
Example 8 Chinese medicinal composition (Ba) for treating spleen-stomach deficiency-cold type chronic gastritis by applying to acupuncture points and applying externally
Taking the traditional Chinese medicine composition: 8 parts of rhizoma atractylodis, 8 parts of agastache rugosus, 11 parts of costus root, 11 parts of fennel, 13 parts of prepared rhizoma cyperi, 10 parts of fenugreek and 7 parts of dried ginger.
Example 9 Chinese medicinal composition for treating chronic gastritis due to deficiency-cold of spleen and stomach by acupoint application
Taking the traditional Chinese medicine composition: 10 parts of rhizoma atractylodis, 10 parts of agastache rugosus, 13 parts of costus root, 13 parts of fennel, 11 parts of prepared rhizoma cyperi, 8-parts of fenugreek and 5 parts of dried ginger.
Example 10 Point application of A Chinese medicinal composition for external treatment of spleen-stomach deficiency-cold type chronic gastritis
Taking the traditional Chinese medicine composition: 8 parts of rhizoma atractylodis, 10 parts of agastache rugosus, 11 parts of costus root, 13 parts of fennel, 11 parts of prepared rhizoma cyperi, 10 parts of fenugreek and 5 parts of dried ginger.
Example 11 Point application of A Chinese medicinal composition for treating chronic gastritis due to deficiency-cold of spleen and stomach
Taking the traditional Chinese medicine composition: 10 parts of rhizoma atractylodis, 8 parts of agastache rugosus, 13 parts of costus root, 11 parts of fennel, 13 parts of prepared rhizoma cyperi, 8 parts of fenugreek and 7 parts of dried ginger.
Example 12 Chinese medicinal composition for treating chronic gastritis due to deficiency-cold of spleen and stomach by applying to acupuncture points (twelve)
Taking the traditional Chinese medicine composition: 8 parts of rhizoma atractylodis, 8 parts of agastache rugosus, 13 parts of costus root, 13 parts of fennel, 11 parts of prepared rhizoma cyperi, 8 parts of fenugreek and 7 parts of dried ginger.
Example 13 Chinese medicinal composition for external treatment of spleen-stomach deficiency-cold type chronic gastritis by acupoint application (thirteen)
Taking the traditional Chinese medicine composition: 10 parts of rhizoma atractylodis, 10 parts of agastache rugosus, 11 parts of costus root, 11 parts of fennel, 13 parts of prepared rhizoma cyperi, 10 parts of fenugreek and 5 parts of dried ginger.
Example 14 Point application for the treatment of spleen and stomach deficiency-cold type chronic gastritis
The Chinese medicinal composition of any one of examples 1-13 is prepared by grinding the above materials into powder, and concocting with old vinegar to obtain ointment (3 g ointment is required for each patch, the ointment has a degree of dryness and wetness which can be fixed on the patch material without dropping, and the old vinegar is heated to 35 deg.C close to body surface temperature).
The using method comprises the following steps: (1) the required equipment: 75% alcohol cotton ball, application material for fixing external use, and external use microwave therapeutic apparatus (SW-61A series microwave therapeutic apparatus from Shunfo medical equipment Co., Ltd., Tianjin). (2) Selection of acupoints: pishu (1.5 cun lateral to the spinous process of the 11 th thoracic vertebra), Zhongwan (4 cun above the umbilicus, anterior midline), Zusanli (3 cun below the calf anterior lateral aspect, one transverse finger from the anterior border of the tibia), Guanyuan (three cun below the anterior midline).
After the medicine is prepared, the medicine is put beside the patient, and the patient can be well explained and matched with the awake patient. The patient takes the sitting position and uses a 75% alcohol cotton ball to carry out routine disinfection on the skin near the acupuncture point. After the alcohol is volatilized, a proper amount of the blended external medicine is smeared on the application materials and is sequentially pasted on the corresponding acupuncture points of the patient. The plaster paper is cut into 5.5cm × 7cm each time, and can be used as external fixing plaster paper for treating ostealgia (Guilin Huarun Tian and pharmaceutical industry Co., Ltd., approval document: Chinese medicine Standard Z10980134, specification: 11cm × 14cm), etc., the external application material is prepared by mixing 3g of dry weight of the used medicinal powder for each acupoint with 10ml of old vinegar to obtain plaster, the plaster is about 2cm in diameter and 0.3cm in thickness, and is fixed in the middle of the plaster paper by the plaster paper and then pasted on the corresponding acupoint. Wherein Pishu and Zusanli should be applied on both sides. After the plaster is finished, microwave-assisted treatment is carried out. The microwave treatment standard process comprises the following steps: starting the microwave therapeutic machine, preheating the standby device and finishing self-checking, regulating the power to 20W, and setting the time to 5 minutes. The microwave radiator is directed at the epigastrium, Guanyuan, Pishu on both sides and Zusanli on both sides of the patient, and is 10 to 15 cm away from the patient, and each acupoint should be irradiated and heated for five minutes.
EXAMPLE 15 Current State of use of the Point application of the invention
The invention is a clinical proved recipe of Liuyan of a doctor in medical department of traditional Chinese medical hospital in Shanghai, and the treatment method is tried to be brought into clinical routine diagnosis and treatment from 2016 years, so that the clinic is remarkably increased up to now. Statistics show that the number of outpatient applications in 2016-2018 is increased from 260 to more than 1000 per year. The single benefit is doubled from 34000 yuan to 65000 yuan per year, and the achievement is remarkable. Under the support of relevant leadership of the hospital, the inventor gives up the experience of clinical application technology by Liuyan chief physicians, and the inventor reports that the project of Wei Jiyu project of Shanghai in 2017, that is, the 'clinical research on treating spleen deficiency phlegm stasis type chronic atrophic gastritis by combining the Zhongyuan prescription with the acupoint application technology', establishes success, and through rough statistics, the mucosa under gastroscope applied by using external medicine by acupoint application has the cure rate of more than 90 percent, the mucosa pathological cure rate is obviously higher than that of a control group, and even partial patients have completely disappeared the mucosa precancerous lesion; an academic review paper has been published by the doctor skilled in the art for Liuyan: chinese patent medicine 2017, 39 (12): 2564; the subject group led by the doctor of the chief of Liuyan in 2018 honors the apricot forest innovation prize of the traditional Chinese medical hospital in the market by the technical treatment method. The method can obviously and quickly improve clinical symptoms and congestion, edema and erosion of gastric mucosa, is beneficial to the repair of atrophy and intestinal glandular metaplasia mucosa, shortens the course of treatment, makes up for the vacancy of part of western medicine for treating the disease, and has wider development prospect.
Effects of the embodiment
1 clinical data
1.1 sources of cases
Patients were selected from the outpatient clinic between 2016 and 2018. 91 patients meeting the requirements are selected, signed with an informed consent, and divided into 34 cases of Chinese medicine 1 group, 30 cases of Chinese medicine 2 group and 27 cases of contrast group by adopting a random grouping method.
1.2 diagnostic criteria
Western diagnostic criteria: clinically, it is usually manifested as pain and discomfort in the stomach, accompanied by stuffiness and fullness, belching and acid regurgitation. Gastroscopy and pathology prompt: the mucous membrane of stomach and duodenum has inflammation change and eliminates organic lesions such as gastric ulcer, tumor, polyp, etc. Congestion, edema and exudation of gastric mucosa can be seen under the endoscope, and spot-like and flaky erythema can be seen, local mucosa is rough and uneven and is red and white alternately, and blood vessel lines can be seen on the mucosa under the gastroscope in some cases.
The traditional Chinese medicine diagnosis standard is as follows: the main symptoms are: (1) dull pain in the gastric cavity; (2) fullness in the stomach; (3) it is good for pressing and warming. The secondary symptoms are as follows: (1) anorexia and anorexia; (2) loose stool; (3) preferring warm and press; (4) the hands and feet are not warm. Tongue pulse condition: a pale, swollen and teeth-marked tongue with thin and white coating and a deep, thready or thready and slippery pulse. And (3) symptom type determination: when the tongue and pulse conditions of the patient are consistent with the main symptoms of 3 or have the 1 st item and the 2 nd item with the secondary symptoms, the diagnosis can be made.
2 method
2.1 methods of treatment
1 group of traditional Chinese medicines: the acupuncture point application treatment was performed by using the Chinese medicinal composition of example 1 according to the method of example 14, as follows: taking the traditional Chinese medicine composition: 9g of rhizoma atractylodis, 9g of agastache rugosus, 12g of costus root, 12g of fennel, 12g of prepared rhizoma cyperi, 9g of fenugreek and 6g of dried ginger. The above materials are ground into powder, and mixed with old vinegar to obtain ointment (the ointment has a dry and wet degree which can be fixed on the application material, and the old vinegar is heated to 35 deg.C close to body surface temperature), wherein the ointment is used 3g per application material. Selection of acupoints: pishu (1.5 cun lateral to the spinous process of the 11 th thoracic vertebra), Zhongwan (4 cun above the umbilicus, anterior midline), Zusanli (3 cun below the calf anterior lateral aspect, one transverse finger from the anterior border of the tibia), Guanyuan (three cun below the anterior midline). After the articles are prepared, the articles are arranged beside the patient, and the clear patient is well explained and matched; the patient takes the sitting position and uses a 75% alcohol cotton ball to carry out routine disinfection on the skin near the acupuncture point. After the alcohol is volatilized, a proper amount of the blended external medicine is smeared on the application materials and is sequentially pasted on the corresponding acupuncture points of the patient. The plaster paper is cut into 5.5cm × 7cm each time, and can be used as external fixing plaster paper for treating ostealgia (Guilin Huarun Tian and pharmaceutical industry Co., Ltd., approval document: Chinese medicine Standard Z10980134, specification: 11cm × 14cm), etc., the external application material is prepared by mixing 3g of dry weight of the used medicinal powder for each acupoint with 10ml of old vinegar to obtain plaster, the plaster is about 2cm in diameter and 0.3cm in thickness, and is fixed in the middle of the plaster paper by the plaster paper and then pasted on the corresponding acupoint. Wherein Pishu and Zusanli should be applied on both sides. After the plaster is finished, microwave-assisted treatment is carried out. The microwave treatment standard process comprises the following steps: starting the microwave therapeutic machine, preheating the standby device and finishing self-checking, regulating the power to 20W, and setting the time to 10 minutes. The microwave radiator is directed at the epigastrium, Guanyuan, Pishu on both sides and Zusanli on both sides of the patient, and is about 10 to 15 cm away from the patient, and each acupoint should be irradiated and heated for 10 minutes. The course of treatment is as follows: the patch is applied twice every three days, and is removed four hours after each treatment, and the curative effect is counted after 6 months of continuous treatment.
And (3) traditional Chinese medicine 2 groups: the following Chinese medicinal composition is taken: 9g of rhizoma atractylodis, 9g of agastache rugosus, 12g of costus root, 12g of fennel and 6g of dried ginger, and the acupoint application treatment is carried out according to the method in the embodiment 14. The above materials are ground into powder, and mixed with old vinegar to obtain ointment (the ointment has a dry and wet degree which can be fixed on the application material, and the old vinegar is heated to 35 deg.C close to body surface temperature), wherein the ointment is used 3g per application material. Selection of acupoints: pishu (1.5 cun lateral to the spinous process of the 11 th thoracic vertebra), Zhongwan (4 cun above the umbilicus, anterior midline), Zusanli (3 cun below the calf anterior lateral aspect, one transverse finger from the anterior border of the tibia), Guanyuan (three cun below the anterior midline). After the articles are prepared, the articles are arranged beside the patient, and the clear patient is well explained and matched; the patient takes the sitting position and uses a 75% alcohol cotton ball to carry out routine disinfection on the skin near the acupuncture point. After the alcohol is volatilized, a proper amount of the blended external medicine is smeared on the application materials and is sequentially pasted on the corresponding acupuncture points of the patient. The plaster paper is cut into 5.5cm × 7cm each time, and can be used as external fixing plaster paper for treating ostealgia (Guilin Huarun Tian and pharmaceutical industry Co., Ltd., approval document: Chinese medicine Standard Z10980134, specification: 11cm × 14cm), etc., the external application material is prepared by mixing 3g of dry weight of the used medicinal powder for each acupoint with 10ml of old vinegar to obtain plaster, the plaster is about 2cm in diameter and 0.3cm in thickness, and is fixed in the middle of the plaster paper by the plaster paper and then pasted on the corresponding acupoint. Wherein Pishu and Zusanli should be applied on both sides. After the plaster is finished, microwave-assisted treatment is carried out. The microwave treatment standard process comprises the following steps: starting the microwave therapeutic machine, preheating the standby device and finishing self-checking, regulating the power to 20W, and setting the time to 10 minutes. The microwave radiator is directed at the epigastrium, Guanyuan, Pishu on both sides and Zusanli on both sides of the patient, and is about 10 to 15 cm away from the patient, and each acupoint should be irradiated and heated for 10 minutes. The course of treatment is as follows: the patch is applied twice every three days, and is removed two to four hours after each treatment, and the curative effect is counted after 6 months of continuous treatment.
Control group: folic acid group (Shanghai Xin Yihuanghe pharmaceutical Co., Ltd., national Standard H31020147, specification of 5mg × 100 tablets, batch No. 130101), 10mg each time, 3 times a day, and 6 months as a treatment course.
2.2 evaluation criteria for therapeutic Effect
The judgment is made according to the standard of curative effect of diagnosis of the traditional Chinese medicine diseases. The standard of cure is as follows: the epigastric pain and other symptoms disappear, and the gastroscopy shows that the epigastric pain and other symptoms are normal; improvement standard: the epigastric pain is relieved, the attack frequency is reduced, other symptoms are relieved, and improvement is shown by adopting gastroscopy; invalidation criteria: epigastric pain and clinical symptoms are not improved, and no change is caused by gastroscopy.
3 results
The results are shown in table 1, 13 cases are cured in 1 group of traditional Chinese medicines, 20 cases are improved, 1 case is invalid, and the total effective rate is 97.06%; the 2 groups of the traditional Chinese medicines cure 8 cases, 18 cases are improved, 4 cases are invalid, and the total effective rate is 86.67%; the control group has 3 cured cases, 20 improved cases and 4 ineffective cases, and the total effective rate is 85.19%. Clinical results show that the traditional Chinese medicine composition can effectively treat the spleen and stomach deficiency-cold type chronic gastritis by acupoint application, can obviously and quickly improve clinical symptoms and hyperemia, edema and erosion of gastric mucosa, is beneficial to the repair of atrophy and intestinal glandular metaplasia mucosa, shortens the treatment course, makes up for the vacancy of partial western medicine for treating the disease, and has wide market development prospect.
TABLE 1 comparison of clinical efficacy of three groups of patients [ case (%) ]
Group of Number of examples Cure of disease Improvement of life Invalidation Total effective
Chinese medicine 1 group 34 13 20 1 33(97.06%)
Chinese medicine 2 groups 30 8 18 4 26(86.67%)
Control group 27 3 20 4 23(85.19%)
The clinical research data prove that the formula ratio of the traditional Chinese medicine is optimized in 2016-2018. For the person skilled in the art, several modifications and additions can be made without departing from the method of the invention, which should also be considered as the scope of protection of the invention.

Claims (9)

1. An acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis is characterized by being prepared by the following method: taking 7-11 parts of rhizoma atractylodis, 7-11 parts of wrinkled gianthyssop herb, 10-14 parts of costus root, 10-14 parts of common fennel fruit, 10-14 parts of prepared nutgrass galingale rhizome, 7-11 parts of common fenugreek seed and 4-8 parts of dried ginger; grinding the above materials into powder, adding liquid matrix, concocting to obtain ointment, and fixing the ointment on patch material to obtain acupoint patch.
2. The acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis according to claim 1, which is prepared by the following method: taking 8-10 parts of rhizoma atractylodis, 8-10 parts of agastache rugosus, 11-13 parts of costus root, 11-13 parts of fennel, 11-13 parts of prepared rhizoma cyperi, 8-10 parts of fenugreek and 5-7 parts of dried ginger; grinding the above materials into powder, adding liquid matrix, concocting to obtain ointment, and fixing the ointment on patch material to obtain acupoint patch.
3. The acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis according to claim 2, which is prepared by the following method: taking 9 parts of rhizoma atractylodis, 9 parts of agastache rugosus, 12 parts of costus root, 12 parts of fennel, 12 parts of prepared rhizoma cyperi, 9 parts of fenugreek and 6 parts of dried ginger; grinding the above materials into powder, adding liquid matrix, concocting to obtain ointment, and fixing the ointment on patch material to obtain acupoint patch.
4. The acupoint application for treating spleen-stomach deficiency-cold type chronic gastritis according to any one of claims 1 to 3, wherein the liquid matrix is mature vinegar in the following amounts: adding 5-20ml of mature vinegar into 3g of the medicinal powder for blending.
5. The patch according to any of claims 1-3, wherein the acupoints are Pishu, Zhongwan, Zusanli and Guanyuan.
6. The traditional Chinese medicine composition for treating spleen-stomach deficiency-cold type chronic gastritis by being applied to acupuncture points and externally treating the spleen-stomach deficiency-cold type chronic gastritis is characterized by being prepared from the following raw material medicines in parts by weight: 7-11 parts of rhizoma atractylodis, 7-11 parts of agastache rugosus, 10-14 parts of costus root, 10-14 parts of fennel, 10-14 parts of prepared rhizoma cyperi, 7-11 parts of fenugreek and 4-8 parts of dried ginger.
7. The traditional Chinese medicine composition for treating spleen-stomach deficiency-cold type chronic gastritis by applying to acupuncture points and applying externally as claimed in claim 6, wherein the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 8-10 parts of rhizoma atractylodis, 8-10 parts of agastache rugosus, 11-13 parts of costus root, 11-13 parts of fennel, 11-13 parts of prepared rhizoma cyperi, 8-10 parts of fenugreek and 5-7 parts of dried ginger.
8. The traditional Chinese medicine composition for treating spleen-stomach deficiency-cold type chronic gastritis by applying to acupuncture points according to claim 7, is characterized by being prepared from the following raw material medicines in parts by weight: 9 parts of rhizoma atractylodis, 9 parts of agastache rugosus, 12 parts of costus root, 12 parts of fennel, 12 parts of prepared rhizoma cyperi, 9 parts of fenugreek and 6 parts of dried ginger.
9. The use of the Chinese medicinal composition of any one of claims 6-8 in the preparation of a medicament for treating chronic gastritis due to deficiency-cold of the spleen and stomach, wherein the medicament is applied to acupuncture points which are Pishu, Zhongwan, Zusanli and Guanyuan.
CN201910130601.7A 2019-02-21 2019-02-21 Traditional Chinese medicine composition for externally treating spleen-stomach deficiency-cold type chronic gastritis by acupoint application and application thereof Active CN109758565B (en)

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Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
柴平汤联合超短波加贴敷治疗慢性浅表性胃炎疗效观察;何磊等;《现代中西医结合杂志》;20101031;第19卷(第28期);第3609-3610页,尤其是第3609页右栏第1段 *
腹痛宁煎剂治疗慢性胃炎129例;王义亮等;《成都中医药大学学报》;20040930;第27卷(第3期);第14-15页,尤其是第14页第2.1节中药组 *

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