CN1097313A - Snake spirit for rheumatism and compound method - Google Patents
Snake spirit for rheumatism and compound method Download PDFInfo
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- CN1097313A CN1097313A CN93108744A CN93108744A CN1097313A CN 1097313 A CN1097313 A CN 1097313A CN 93108744 A CN93108744 A CN 93108744A CN 93108744 A CN93108744 A CN 93108744A CN 1097313 A CN1097313 A CN 1097313A
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Abstract
The invention discloses a kind of prescription and manufacture method of snake spirit for rheumatism, be characterized in using Carnis Serpentis, Herba Epimedii, Radix Notoginseng is formed, be equipped with Radix Rehmanniae again, Herba Cistanches, Fructus Lycii, plurality of Chinese such as the river is alive are with the medicated wine of Chinese liquor preparation, be mainly used in the treatment rheumatic arthritis, rheumatoid arthritis, diseases such as scapulohumeral periarthritis, and the effect of improving blood circulation and cough with asthma symptom arranged, this Serpentis wine has the curative effect height through the test and the detection of science, the rheumatic arthritis effective percentage is reached more than 90%, the advantage that toxic and side effects is little is a kind of treatment rheumatism and improve sanguimotor efficacy type wine, also can take strong health for a long time.
Description
The invention belongs to the medicated wine and the compound method thereof that contain Chinese medicine and Serpentis.
At present, the kind of existing snake medicinal liquor is a lot, a lot of wine all are processings on the basis of traditional medicated wine, principle according to Serpentis wine energy promoting blood circulation by removing wind, these Serpentis wine can both have certain therapeutical effect to rheumatism, formally list the three snakes liquor that has of state-promulgated pharmacopoeia in China, the only use Serpentis that other has, though what have is aided with some Chinese herbal medicine, but because therefore selecting for use and the traditional experience of processing technology aspect dependence of Chinese herbal medicine, all exist some not too reasonably local in these areas, thereby influenced curative effect, and the bigger toxicity in addition that has.In addition,, lack a kind of analysis of science and test, the observation and the research of system are not carried out in aspects such as its pharmacology, toxicity, therefore have subjective and unilateral understanding easily owing to be to be based upon on the basis of traditional experience and understanding.
The objective of the invention is to invent a kind of on the basis of people to Serpentis wine traditional understanding, by analysis of science and test, and aspects such as its pharmacology, toxicity are carried out the observation of system and research, rheumatism there are obvious therapeutic effect and hypotoxic Serpentis wine and compound method thereof.
Snake spirit for rheumatism of the present invention is such by medicated wine 4000-6000 milliliter, Carnis Serpentis 100-300 gram, Herba Epimedii 5-42 gram, Radix Notoginseng 5-15 restrains composition, Carnis Serpentis can be selected Bungarus fasciatus, Agkistrodon, Zaocys, Crotalinae Serpentis, variegated snake or other Serpentis for use, and its Chinese medicinal liquor can be mixed with by following four kinds of schemes; First kind of scheme is to add Radix Rehmanniae 35-75 gram in 4000-6000 milliliter Chinese liquor, Herba Cistanches 20-40 gram, and Fructus Lycii 20-40 gram, Rhizoma Chuanxiong 20-40 gram, Herba Siegesbeckiae 25-75 gram, Radix Angelicae Sinensis 25-75 gram, Rhizoma Et Radix Notopterygii 25-75 gram, Radix Saposhnikoviae 20-40 restrains composition; Alternative plan is to add Cordyceps (dry powder) 20-40 gram in 4000-6000 milliliter Chinese liquor, Radix Glycyrrhizae 15-25 gram, and Fructus Lycii 20-40 restrains composition; Third party's case is to add Radix Glycyrrhizae 5-15 gram in 4000-6000 milliliter Chinese liquor, Fructus Lycii 20-40 gram, and Fructus Jujubae 15-25 restrains composition.The 4th kind of scheme is the used Chinese liquor of medicated wine for generally drinking.The compound method of snake spirit for rheumatism of the present invention is that such Carnis Serpentis 100-300 that adds in 4000-6000 milliliter medicated wine restrains, and Herba Epimedii 5-42 gram through filtering, makes behind the elimination impurity after Radix Notoginseng 3-10 gram and airtight immersion 40-45 are natural.Used Carnis Serpentis is fresh Carnis Serpentis or freezing Carnis Serpentis.
Effect of the present invention is such, mainly contains wind-damp dispelling, and the repercussive pain relieving is used for rheumatic arthritis, rheumatalgia, extremities joint pain, hyperosteogeny, diseases such as waist and leg ache.Snake spirit for rheumatism of the present invention and more existing treatment rheumatic medicines are as the comparative result of oral sodium salicylate and three snakes liquor is, after rat ankle joint injection fresh albumen made the acute arthritis model, relatively more for oral administration, be coated with the therapeutical effect of snake spirit for rheumatism and oral sodium salicylate outward.The result shows that the two all has obvious therapeutic action to rat acute arthritis.With contrast ratio P＜0.01.Also observe snake spirit for rheumatism simultaneously under the treatment effective dose, curative effect is directly proportional with dosage.Control case sees Table 1.
Snake spirit for rheumatism is close with the rheumatism medicine salicyate therapy effect of generally acknowledging both at home and abroad as can be seen from Table 1.
After rabbit knee joint injection formalin caused the chronic arthritis model, take and be coated with three snakes liquor and snake spirit for rheumatism orally outward, the result shows that the two all has therapeutical effect preferably to chronic rheumatic arthritis, with contrast ratio P＜0.01, main therapeutic effect is reflected at behind the injection formaldehyde 3-8 days, and the therapeutic effect of snake spirit for rheumatism is better than three snakes liquor, and control case sees Table 2.
In addition, proved also that simultaneously snake spirit for rheumatism induces aggregating agent prepared therefrom ADP(adenosine diphosphate to platelet), the AA(arachidonic acid) approach has obvious inhibitory action, and to TMVA(Trimeresurus mucrosquamatus toxenia platelet acrasin) induce to assemble and suppress not obvious.Control case sees Table 3, and these results show not only low toxicity but also effective of snake spirit for rheumatism.
In sum, the present invention a kind ofly invents on the basis of people to Serpentis wine traditional understanding, by analysis of science and test, and the snake spirit for rheumatism that its pharmacology, toxicity etc. has been carried out the observation and the research of system, verify through the many cases case, it reaches more than 90% the rheumatic arthritis effective percentage, to other rheumatoid arthritis effective percentage reach more than 80%, the scapulohumeral periarthritis effective percentage reaches more than 75%, the sciatica effective percentage reaches more than 70%, do not see obvious toxicity from patient's application result, and can also improve blood circulation and cough with asthma symptom, enhancing human body immunity.Particularly the insomniac sleeps and obviously improves.
Below be several embodiment of snake spirit for rheumatism of the present invention:
Embodiment one; In 4000 milliliters of Chinese liquor, add Radix Rehmanniae 35 grams, Herba Cistanches 20 grams, Fructus Lycii 20 grams, Rhizoma Chuanxiong 20 grams, Herba Siegesbeckiae 25 grams, Radix Angelicae Sinensis 25 gram, Rhizoma Et Radix Notopterygii 25 grams, Radix Saposhnikoviae 20 restrain medicated wine, with Bungarus fasciatus Carnis Serpentis 100 grams, Herba Epimedii 18 grams, airtight immersion is 40-45 days in the Radix Notoginseng 5 gram adding medicated wine, gets product after the filtration.
Embodiment two; In 5000 milliliters of Chinese liquor, add Radix Rehmanniae 55 grams, Herba Cistanches 33 grams, Fructus Lycii 35 grams, Rhizoma Chuanxiong 27 grams, Herba Siegesbeckiae 45 grams, Radix Angelicae Sinensis 55 gram, Rhizoma Et Radix Notopterygii 55 grams, Radix Saposhnikoviae 35 restrain medicated wine, with Agkistrodon Carnis Serpentis 250 grams, Herba Epimedii 25 grams, airtight immersion is 40-45 days in the Radix Notoginseng 10 gram adding medicated wine, gets product after the filtration.
Embodiment three; In 6000 milliliters of Chinese liquor, add Radix Rehmanniae 75 grams, Herba Cistanches 40 grams, Fructus Lycii 40 grams, Rhizoma Chuanxiong 40 grams, Herba Siegesbeckiae 75 grams, Radix Angelicae Sinensis 75 gram, Rhizoma Et Radix Notopterygii 75 grams, Radix Saposhnikoviae 40 restrain medicated wine, with Zaocys Carnis Serpentis 300 grams, Herba Epimedii 42 grams, airtight immersion is 40-45 days in the Radix Notoginseng 15 gram adding medicated wine, gets product after the filtration.
Embodiment four; In 5000 milliliters of Chinese liquor, add Carnis Zaocys 250 grams, Herba Epimedii 5 grams, the airtight immersion of Radix Notoginseng 10 grams 40-45 days gets product after the filtration.
Embodiment five; In 4500 milliliters of Chinese liquor, add Cordyceps (dry powder) 25 gram, Radix Glycyrrhizae 16 grams, Fructus Lycii 25 restrain medicated wine, again with variegated snake Carnis Serpentis 125 grams, Herba Epimedii 20 grams, Radix Notoginseng 6 grams added in the medicated wine airtight immersions 40-45 days, got product after the filtration.
Embodiment six; In 6000 milliliters of Chinese liquor, add Cordyceps (dry powder) 40 gram, Radix Glycyrrhizae 25 grams, Fructus Lycii 40 restrain medicated wine, again with Trimeresurus mucrosquamatus Carnis Serpentis 300 grams, Herba Epimedii 42 grams, Radix Notoginseng 15 grams added in the medicated wine airtight immersions 40-45 days, got product after the filtration.
Embodiment seven; In 5500 milliliters of Chinese liquor, add Radix Glycyrrhizae 13 grams, Fructus Lycii 35 grams, Fructus Jujubae 23 restrain medicated wine, again with Bungarus fasciatus Carnis Serpentis 270 grams, Herba Epimedii 40 grams, Radix Notoginseng 11 grams added in the medicated wine airtight immersions 40-45 days, got product after the filtration.
Embodiment eight; In 4000 milliliters of Chinese liquor, add Radix Glycyrrhizae 5 grams, Fructus Lycii 20 grams, Fructus Jujubae 15 restrain medicated wine, add Agkistrodon Carnis Serpentis 100 grams again, Herba Epimedii 18 grams, Radix Notoginseng 5 grams added in the medicated wine airtight immersions 40-45 days, got product after the filtration.
Claims (6)
1, a kind of snake spirit for rheumatism is characterized in that the gram by Carnis Serpentis 100--300, Herba Epimedii 5--42 gram, and Radix Notoginseng 5--15 gram, medicated wine 4000--6000 milliliter is formed.
2, snake spirit for rheumatism as claimed in claim 1, it is characterized in that described medicated wine is by add Radix Rehmanniae 35-75 gram in 4000-6000 milliliter Chinese liquor, Herba Cistanches 20-40 gram, Fructus Lycii 20-40 gram, Rhizoma Chuanxiong 20-40 gram, Herba Siegesbeckiae 25-75 gram, Radix Angelicae Sinensis 25-75 gram, Rhizoma Et Radix Notopterygii 25-75 gram, Radix Saposhnikoviae 20-40 restrains composition.
3, snake spirit for rheumatism as claimed in claim 1 is characterized in that described medicated wine by add Cordyceps (dry powder) 20-40 gram in 4000-6000 milliliter Chinese liquor, and Radix Glycyrrhizae 15-25 restrains, and Fructus Lycii 20-40 restrains composition.
4, snake spirit for rheumatism as claimed in claim 1 is characterized in that described medicated wine by add Radix Glycyrrhizae 5-15 gram in 4000-6000 milliliter Chinese liquor, and Fructus Lycii 20-40 restrains, and Fructus Jujubae 15-25 restrains composition.
5, snake spirit for rheumatism as claimed in claim 1 is characterized in that described medicated wine is Chinese liquor.
6, a kind of compound method of snake spirit for rheumatism; It is characterized in that in medicated wine, adding Carnis Serpentis, Herba Epimedii, the airtight immersion of Radix Notoginseng 40-45 days makes through filtering then.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93108744A CN1060048C (en) | 1993-07-15 | 1993-07-15 | Snake spirit for rheumatism and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93108744A CN1060048C (en) | 1993-07-15 | 1993-07-15 | Snake spirit for rheumatism and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1097313A true CN1097313A (en) | 1995-01-18 |
| CN1060048C CN1060048C (en) | 2001-01-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93108744A Expired - Fee Related CN1060048C (en) | 1993-07-15 | 1993-07-15 | Snake spirit for rheumatism and its preparation |
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| CN (1) | CN1060048C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8003139B2 (en) | 2002-04-09 | 2011-08-23 | Sichuan Institute Of Chinese Materia Medica | Pharmaceutical composition for treating rheumatism, and method of making same |
| CN104109610A (en) * | 2014-06-23 | 2014-10-22 | 汪从新 | Snake meat blood-circulation-invigorating qi-benefitting wine and preparation method thereof |
| CN105311240A (en) * | 2015-11-10 | 2016-02-10 | 芜湖永昌生物科技有限公司 | Snake wine for treating rheumatism and preparation process of snake wine |
-
1993
- 1993-07-15 CN CN93108744A patent/CN1060048C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8003139B2 (en) | 2002-04-09 | 2011-08-23 | Sichuan Institute Of Chinese Materia Medica | Pharmaceutical composition for treating rheumatism, and method of making same |
| CN104109610A (en) * | 2014-06-23 | 2014-10-22 | 汪从新 | Snake meat blood-circulation-invigorating qi-benefitting wine and preparation method thereof |
| CN105311240A (en) * | 2015-11-10 | 2016-02-10 | 芜湖永昌生物科技有限公司 | Snake wine for treating rheumatism and preparation process of snake wine |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1060048C (en) | 2001-01-03 |
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Owner name: YUNNAN BIOTECH PHARMACEUTICALS CO.,LTD Free format text: FORMER OWNER: ZOOTOXIN AND SNAKE RESOURCES DEVELOPMENT CENTER, KUNMING ANIMALS INST., CHINESE Effective date: 20030321 |
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Effective date of registration: 20030321 Address after: Xiong Yuliang, Kunming Institute of animal research, 32 Teaching Road East, Yunnan, Kunming Province Patentee after: Zhongke Yun Medicine Co., Ltd., Yunnan Address before: Dismount Village, Kunming, Yunnan Patentee before: Zootoxin and Snake Resources Development Center, Kunming Animals Inst., Chinese |
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Owner name: MERCEDES-BENZ BIOTECHNOLOGY (YUNNAN) CO. Free format text: FORMER OWNER: YUNNAN BIOTECH PHARMACEUTICALS CO.,LTD Effective date: 20070608 |
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Effective date of registration: 20070608 Address after: 650106, No. 5, building 625, No. two West Ring Road, Kunming hi tech Zone, Yunnan, 5502 Patentee after: Benchi Biological Science & Technology (Yunnan) Co., Ltd. Address before: 650223 Xiong Yuliang, Kunming Institute of animal research, 32 Teaching Road East, Yunnan, Kunming Patentee before: Zhongke Yun Medicine Co., Ltd., Yunnan |
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Granted publication date: 20010103 Termination date: 20120715 |