CN109715078B - 组织抓握装置和相关方法 - Google Patents

组织抓握装置和相关方法 Download PDF

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Publication number
CN109715078B
CN109715078B CN201780056353.5A CN201780056353A CN109715078B CN 109715078 B CN109715078 B CN 109715078B CN 201780056353 A CN201780056353 A CN 201780056353A CN 109715078 B CN109715078 B CN 109715078B
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arms
valve
leaflet
arm
capture
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CN109715078A (zh
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拉古维尔·巴苏德
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Medfree Inc
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Medfree Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/128Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
    • A61B17/1285Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips for minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/12Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
    • A61B17/122Clamps or clips, e.g. for the umbilical cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/246Devices for obstructing a leak through a native valve in a closed condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2466Delivery devices therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/00234Surgical instruments, devices or methods for minimally invasive surgery
    • A61B2017/00292Surgical instruments, devices or methods for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003Steerable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00681Aspects not otherwise provided for
    • A61B2017/00694Aspects not otherwise provided for with means correcting for movement of or for synchronisation with the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00778Operations on blood vessels
    • A61B2017/00783Valvuloplasty
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00831Material properties
    • A61B2017/0084Material properties low friction
    • A61B2017/00849Material properties low friction with respect to tissue, e.g. hollow organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22057Optical properties
    • A61B2017/22059Optical properties transparent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/22Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22062Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation to be filled with liquid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation
    • A61B2090/373Surgical systems with images on a monitor during operation using light, e.g. by using optical scanners
    • A61B2090/3735Optical coherence tomography [OCT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3995Multi-modality markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)
CN201780056353.5A 2016-07-13 2017-07-13 组织抓握装置和相关方法 Active CN109715078B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662361953P 2016-07-13 2016-07-13
US62/361,953 2016-07-13
PCT/US2017/042003 WO2018013856A1 (en) 2016-07-13 2017-07-13 Tissue grasping devices and related methods

Publications (2)

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CN109715078A CN109715078A (zh) 2019-05-03
CN109715078B true CN109715078B (zh) 2022-05-27

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EP (1) EP3484375A4 (https=)
JP (4) JP7206191B2 (https=)
CN (1) CN109715078B (https=)
WO (1) WO2018013856A1 (https=)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10517719B2 (en) 2008-12-22 2019-12-31 Valtech Cardio, Ltd. Implantation of repair devices in the heart
US8449599B2 (en) 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8945177B2 (en) 2011-09-13 2015-02-03 Abbott Cardiovascular Systems Inc. Gripper pusher mechanism for tissue apposition systems
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US9622863B2 (en) 2013-11-22 2017-04-18 Edwards Lifesciences Corporation Aortic insufficiency repair device and method
CN111437068B (zh) 2014-12-04 2023-01-17 爱德华兹生命科学公司 用于修复心脏瓣膜的经皮夹具
ES3001450T3 (en) 2015-05-14 2025-03-05 Edwards Lifesciences Corp Heart valve sealing devices and delivery devices therefor
US10799675B2 (en) 2016-03-21 2020-10-13 Edwards Lifesciences Corporation Cam controlled multi-direction steerable handles
US10835714B2 (en) 2016-03-21 2020-11-17 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US11219746B2 (en) 2016-03-21 2022-01-11 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US10973638B2 (en) 2016-07-07 2021-04-13 Edwards Lifesciences Corporation Device and method for treating vascular insufficiency
US11185413B2 (en) 2016-07-13 2021-11-30 Medfree, Inc. Tissue grasping devices and related methods
US10653862B2 (en) 2016-11-07 2020-05-19 Edwards Lifesciences Corporation Apparatus for the introduction and manipulation of multiple telescoping catheters
US10905554B2 (en) 2017-01-05 2021-02-02 Edwards Lifesciences Corporation Heart valve coaptation device
US11224511B2 (en) 2017-04-18 2022-01-18 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
PL3558169T3 (pl) 2017-04-18 2022-04-04 Edwards Lifesciences Corporation Urządzenia do uszczelniania zastawki serca i urządzenia do ich doprowadzania
US10799312B2 (en) 2017-04-28 2020-10-13 Edwards Lifesciences Corporation Medical device stabilizing apparatus and method of use
US10959846B2 (en) 2017-05-10 2021-03-30 Edwards Lifesciences Corporation Mitral valve spacer device
JP7134229B2 (ja) 2017-07-06 2022-09-09 ラグビア バスデ, 組織把持デバイスおよび関連方法
US11051940B2 (en) 2017-09-07 2021-07-06 Edwards Lifesciences Corporation Prosthetic spacer device for heart valve
US11065117B2 (en) 2017-09-08 2021-07-20 Edwards Lifesciences Corporation Axisymmetric adjustable device for treating mitral regurgitation
US11110251B2 (en) 2017-09-19 2021-09-07 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US10136993B1 (en) 2018-01-09 2018-11-27 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10245144B1 (en) 2018-01-09 2019-04-02 Edwards Lifesciences Corporation Native valve repair devices and procedures
JP7343393B2 (ja) * 2018-01-09 2023-09-12 エドワーズ ライフサイエンシーズ コーポレイション 天然心臓弁修復装置および処置
US10076415B1 (en) 2018-01-09 2018-09-18 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10123873B1 (en) 2018-01-09 2018-11-13 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10973639B2 (en) 2018-01-09 2021-04-13 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10105222B1 (en) 2018-01-09 2018-10-23 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10111751B1 (en) 2018-01-09 2018-10-30 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10238493B1 (en) 2018-01-09 2019-03-26 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10231837B1 (en) 2018-01-09 2019-03-19 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10159570B1 (en) 2018-01-09 2018-12-25 Edwards Lifesciences Corporation Native valve repair devices and procedures
CN111867486B (zh) * 2018-01-16 2024-03-08 迈德福瑞公司 组织抓取装置和相关方法
EP3764918B1 (en) * 2018-03-14 2023-08-23 Boston Scientific Scimed, Inc. Tissue retraction device and delivery system
US11389297B2 (en) 2018-04-12 2022-07-19 Edwards Lifesciences Corporation Mitral valve spacer device
US11207181B2 (en) 2018-04-18 2021-12-28 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
CN119700378A (zh) 2018-04-24 2025-03-28 拉古维尔·巴苏德 可取回的组织抓取装置、间隔物、人造瓣膜及相关方法
WO2019226803A1 (en) 2018-05-22 2019-11-28 Boston Scientific Scimed, Inc. Percutaneous papillary muscle relocation
US10945844B2 (en) 2018-10-10 2021-03-16 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
EP3883500B1 (en) 2018-11-20 2024-11-06 Edwards Lifesciences Corporation Deployment tools for delivering a device to a native heart valve
CN113301869A (zh) 2018-11-21 2021-08-24 爱德华兹生命科学公司 心脏瓣膜密封装置、其递送装置以及取回装置
CR20210312A (es) 2018-11-29 2021-09-14 Edwards Lifesciences Corp Método y aparato de cateterización
JP7480161B2 (ja) * 2019-02-08 2024-05-09 エドワーズ ライフサイエンシーズ コーポレイション 直接的心臓圧力監視
CN113747858B (zh) 2019-02-11 2024-11-01 爱德华兹生命科学公司 心脏瓣膜密封装置及其递送装置
WO2020168081A1 (en) 2019-02-14 2020-08-20 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
SG11202108606PA (en) 2019-02-25 2021-09-29 Edwards Lifesciences Corp Heart valve sealing devices
US11648117B2 (en) * 2019-07-12 2023-05-16 Boston Scientific Scimed, Inc. Devices, systems, and methods for clamping a leaflet of a heart valve
CN112206075B (zh) * 2019-07-12 2025-08-05 上海形状记忆合金材料有限公司 一种经导管植入式心脏瓣膜夹合器
EP4663166A3 (en) * 2019-07-15 2025-12-31 Evalve, Inc. METHODS FOR ACTUATING INDEPENDENT PROXIMAL ELEMENT
CN112274297B (zh) * 2019-07-24 2025-08-01 上海形状记忆合金材料有限公司 一种经导管心脏瓣膜夹合系统
CN112386367B (zh) * 2019-08-12 2025-08-12 杭州德晋医疗科技有限公司 可回收的瓣膜夹合器及瓣膜夹合器回收系统
CA3143014A1 (en) 2019-10-15 2021-04-22 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
EP4062873A4 (en) * 2019-11-19 2023-01-04 Hangzhou Valgen Medtech Co., Ltd. INDEPENDENTLY CONTROLLABLE VALVE CLAMPING SYSTEM
CN114786595B (zh) * 2019-12-09 2025-09-19 波士顿科学国际有限公司 用于瓣膜的边对边修复装置
CN115666408A (zh) * 2020-03-25 2023-01-31 拉古维尔·巴苏德 组织抓取装置及相关方法
WO2022051241A1 (en) 2020-09-01 2022-03-10 Edwards Lifesciences Corporation Medical device stabilizing systems
CN111920549A (zh) * 2020-09-10 2020-11-13 上海纽脉医疗科技有限公司 二尖瓣夹持装置的夹子主体、二尖瓣夹持装置和修复设备
CN114376766B (zh) * 2020-10-21 2025-09-23 杭州端佑医疗科技有限公司 一种可调节可移除的瓣膜夹持装置
CN114432004B (zh) * 2020-11-03 2025-08-29 深圳市健心医疗科技有限公司 组织闭合器械
EP4308042A1 (en) * 2021-03-19 2024-01-24 Evalve, Inc. Systems for tissue grasping and assessment
CN113017929B (zh) * 2021-04-02 2025-02-25 上海汇禾医疗科技有限公司 夹合器械
US20230020981A1 (en) * 2021-07-14 2023-01-19 Boston Scientific Scimed, Inc. Mitral valve leaflet clip
AU2023239164A1 (en) * 2022-03-25 2024-10-10 V2V Medtech Inc. Clips implanted in the heart and great vessels that allow their complete or partial removal, kits and methods to perform such removal
JP2025511411A (ja) * 2022-04-04 2025-04-15 エドワーズ ライフサイエンシーズ コーポレイション 心臓弁修復装置およびそのための送達装置
EP4543309A1 (en) * 2022-06-21 2025-04-30 Boston Scientific Scimed, Inc. Devices, systems, and methods for delivering and deploying an implantable device
JP2025540120A (ja) 2022-12-06 2025-12-11 ボストン サイエンティフィック サイムド,インコーポレイテッド 低侵襲処置中に縫合糸を切断するための医療デバイス
USD1071198S1 (en) 2023-06-28 2025-04-15 Edwards Lifesciences Corporation Cradle
WO2025049449A1 (en) * 2023-08-31 2025-03-06 Evalve, Inc. Fixation system with leaflet capture assessment
CN116999216B (zh) * 2023-09-05 2026-03-20 上海申淇医疗科技股份有限公司 瓣膜夹合装置及瓣膜夹合系统
WO2025254918A1 (en) * 2024-06-05 2025-12-11 Evalve, Inc. Tissue fixation device with enhanced tissue protection
CN120753770B (zh) * 2025-08-11 2026-03-27 上海汇禾医疗科技股份有限公司 一种多功能异物抓捕装置及其操作方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7666204B2 (en) 1999-04-09 2010-02-23 Evalve, Inc. Multi-catheter steerable guiding system and methods of use
US6752813B2 (en) * 1999-04-09 2004-06-22 Evalve, Inc. Methods and devices for capturing and fixing leaflets in valve repair
US9011468B2 (en) * 2011-09-13 2015-04-21 Abbott Cardiovascular Systems Inc. Independent gripper
US8938283B2 (en) * 2011-12-01 2015-01-20 Neochord, Inc. Surgical navigation for repair of heart valve leaflets
US11065118B2 (en) * 2013-03-04 2021-07-20 The Medical Research, Infrastructure And Health Services Fund Of The Tel-Aviv Medical Center Cardiac valve commissure brace
US9572666B2 (en) * 2014-03-17 2017-02-21 Evalve, Inc. Mitral valve fixation device removal devices and methods
US10667815B2 (en) * 2015-07-21 2020-06-02 Evalve, Inc. Tissue grasping devices and related methods

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Publication number Publication date
JP7206191B2 (ja) 2023-01-17
EP3484375A4 (en) 2020-07-22
CN109715078A (zh) 2019-05-03
WO2018013856A1 (en) 2018-01-18
EP3484375A1 (en) 2019-05-22
JP2026012229A (ja) 2026-01-23
JP2022033350A (ja) 2022-02-28
JP2019522555A (ja) 2019-08-15
JP2024019679A (ja) 2024-02-09

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