CN109706058A - Bar magnet magnetosheath fit structure, nucleic acid-extracting apparatus and magnetosheath take method - Google Patents
Bar magnet magnetosheath fit structure, nucleic acid-extracting apparatus and magnetosheath take method Download PDFInfo
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- CN109706058A CN109706058A CN201910186909.3A CN201910186909A CN109706058A CN 109706058 A CN109706058 A CN 109706058A CN 201910186909 A CN201910186909 A CN 201910186909A CN 109706058 A CN109706058 A CN 109706058A
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- 238000000034 method Methods 0.000 title claims abstract description 16
- 239000011324 bead Substances 0.000 claims description 14
- 230000014759 maintenance of location Effects 0.000 claims description 11
- 230000002093 peripheral effect Effects 0.000 claims description 9
- 238000000605 extraction Methods 0.000 abstract description 12
- 150000007523 nucleic acids Chemical class 0.000 abstract description 6
- 102000039446 nucleic acids Human genes 0.000 abstract description 6
- 108020004707 nucleic acids Proteins 0.000 abstract description 6
- 230000000694 effects Effects 0.000 description 11
- 238000010586 diagram Methods 0.000 description 10
- 238000009434 installation Methods 0.000 description 10
- 230000005611 electricity Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000005307 ferromagnetism Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
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- 231100000719 pollutant Toxicity 0.000 description 1
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Abstract
What the application provided a kind of bar magnet magnetosheath fit structure, nucleic acid-extracting apparatus and magnetosheath takes method, belongs to nucleic acid extraction technical field.Bar magnet magnetosheath fit structure, comprising: be equipped with the bar magnet frame of more bar magnets；Magnetosheath frame is provided with the first auxiliary section on magnetosheath frame；The magnetosheath locating rack of more magnetosheaths is installed, is provided with the second auxiliary section on magnetosheath locating rack；When bar magnet frame and magnetosheath locating rack slide in opposition, bar magnet is plugged in magnetosheath, and when magnetosheath frame slides in opposition with magnetosheath locating rack, the first auxiliary section and the cooperation of the second auxiliary section are fixed.The method of taking of magnetosheath includes: that magnetosheath frame is mobile towards the direction of magnetosheath locating rack, and the first auxiliary section and the cooperation of the second auxiliary section are fixed, and magnetosheath locating rack is made to be fixed on magnetosheath frame.Bar magnet frame is mobile towards the direction of magnetosheath locating rack, is plugged in bar magnet in magnetosheath, wherein a bar magnet is plugged in a magnetosheath.This magnetosheath takes method suitable for above-mentioned bar magnet magnetosheath fit structure, can disposably take more magnetosheaths.
Description
Technical field
This application involves nucleic acid extraction technical fields, in particular to a kind of bar magnet magnetosheath fit structure, nucleic acid extraction
Device and magnetosheath take method.
Background technique
The nucleic acid extraction separator of the prior art is extracted using Beads enrichment technology, before extraction, needs hand
It is dynamic that magnetosheath is fixed on one by one on magnetosheath frame, and magnetosheath is set in outside bar magnet, it is removed after finishing, then manually, from
Dynamicization degree is not high, inconvenient.
Summary of the invention
A kind of side of taking for being designed to provide bar magnet magnetosheath fit structure, nucleic acid-extracting apparatus and magnetosheath of the application
Magnetosheath can be mounted on magnetosheath frame automatically and be set in magnetosheath outside bar magnet by method, operate more convenient, raising experiment effect
Rate.
In a first aspect, the embodiment of the present application provides a kind of bar magnet magnetosheath fit structure, comprising: be equipped with the magnetic of more bar magnets
Stick frame.Magnetosheath frame is provided with the first auxiliary section on magnetosheath frame.The magnetosheath locating rack of more magnetosheaths is installed, on magnetosheath locating rack
It is provided with the second auxiliary section.When magnetosheath frame and magnetosheath locating rack slide in opposition, the first auxiliary section and the cooperation of the second auxiliary section are solid
Fixed, when bar magnet frame slides in opposition with magnetosheath locating rack, bar magnet is plugged in magnetosheath.
When needing to take magnetosheath, first magnetosheath frame and magnetosheath locating rack is driven to move toward one another, make magnetosheath frame and magnetosheath
The distance between locating rack shortens, to make the first auxiliary section contact with the second auxiliary section and cooperate fixation, makes magnetosheath locating rack
Be fixed on magnetosheath frame, then bar magnet frame driven to move toward one another with magnetosheath locating rack, make between bar magnet frame and magnetosheath locating rack away from
From shortening, so that bar magnet be allow to be plugged in magnetosheath, taking for magnetosheath is realized.
With reference to first aspect, in another embodiment, the first auxiliary section is positioning pin, and the second auxiliary section is positioning sleeve, fixed
Position pin is plugged in positioning sleeve to be fixed with positioning sleeve cooperation.
When magnetosheath frame and magnetosheath locating rack move toward one another, shorten the distance between magnetosheath frame and magnetosheath locating rack, positioning
It sells towards the direction of positioning sleeve and moves, positioning pin is plugged in positioning sleeve, so that positioning pin be made to be fixed in positioning sleeve, realizes magnetic
Fixation between stock and magnetosheath locating rack.
With reference to first aspect, in another embodiment, the first auxiliary section is positioning sleeve, and the second auxiliary section is positioning pin, fixed
Position is sheathed on outside positioning pin and fixes with detent fit.
When magnetosheath frame and magnetosheath locating rack move toward one another, shorten the distance between magnetosheath frame and magnetosheath locating rack, positioning
It covers and is moved towards the direction of positioning pin, positioning pin is plugged in positioning sleeve, so that positioning pin be made to be fixed in positioning sleeve, realizes magnetic
Fixation between stock and magnetosheath locating rack.
With reference to first aspect, in another embodiment, the outer peripheral surface of positioning pin is provided with the first concaveconvex structure, positioning sleeve
Inner peripheral surface is provided with the second concaveconvex structure, and the first concaveconvex structure and the second concaveconvex structure are engaged by clamping.
Keep the stationary positioned effect between positioning pin and positioning sleeve more preferable, realizes consolidating between magnetosheath frame and magnetosheath locating rack
It is fixed.
With reference to first aspect, in another embodiment, the first concaveconvex structure is set as protrusion, and the second concaveconvex structure is set as
The groove being engaged by clamping with protrusion.Or first concaveconvex structure be set as groove, the second concaveconvex structure, which is set as being clamped with groove, matches
The protrusion of conjunction.
Realize the secure fit between magnetosheath frame and magnetosheath locating rack.
With reference to first aspect, in another embodiment, bar magnet includes first end and second end, and installation is provided on bar magnet frame
Slot, first end are located in mounting groove, and radial direction of the bar magnet relative to bar magnet frame along bar magnet is slidably connected, bar magnet and bar magnet frame
Axial limiting connection is fallen off with limiting first end from the notch of mounting groove, and second end is for being plugged in magnetosheath.
Bar magnet can be moved in radial direction, can be movable during bar magnet grafting enters magnetosheath, make magnetosheath and bar magnet
Between relative motion can occur, do not need accurate installation accuracy, the installation that also can be realized bar magnet and magnetosheath positions.
With reference to first aspect, in another embodiment, stop bosses are arranged in first end, and retention bead portion is along bar magnet
The outer peripheral surface of radial direction protrusion bar magnet；Mounting groove has limit section and necking section, and limit section is connected to necking section, necking section
Internal diameter be less than limit section internal diameter, retention bead portion be located at limit section, second end from necking section stretch out.
Retention bead portion can realize the sliding of radial direction, necking section and the mating reaction for limiting section in limit section,
Realize the installation of bar magnet.
With reference to first aspect, in another embodiment, bar magnet frame includes the first frame body and the second frame body, on the first frame body
Be provided with mounting hole, the second erection of frames is on the first frame body, and the Single port of the second frame body capping mounting hole, the first frame body with
Second frame body limits mounting groove jointly at mounting hole.
Slide bar magnet in radial directions, it is fixed on vertical direction.
Second aspect, the embodiment of the present application provide a kind of nucleic acid-extracting apparatus, including bracket, the first driving assembly, second
Driving assembly and above-mentioned bar magnet magnetosheath fit structure, the first driving assembly and the second driving assembly are all set in bracket, and first drives
Dynamic Component driver connects bar magnet frame, and the second driving assembly is drivingly connected magnetosheath frame.
The movement of bar magnet frame and magnetosheath frame is controlled respectively by the first driving assembly and second driving assembly, to make
Relative motion between bar magnet frame and magnetosheath locating rack, relative motion between magnetosheath frame and magnetosheath locating rack.
The third aspect, what the embodiment of the present application provided a kind of magnetosheath takes method, is suitable for above-mentioned bar magnet magnetosheath cooperation knot
Structure, the method for taking include: that magnetosheath frame is mobile towards the direction of magnetosheath locating rack, and the first auxiliary section and the cooperation of the second auxiliary section are solid
It is fixed, so that magnetosheath locating rack is fixed on magnetosheath frame.Bar magnet frame is mobile towards the direction of magnetosheath locating rack, and bar magnet is made to be plugged in magnetosheath
It is interior, wherein a bar magnet is plugged in a magnetosheath.Realize magnetosheath installation with take.
Detailed description of the invention
Technical solution in ord to more clearly illustrate embodiments of the present application, below will be to needed in the embodiment attached
Figure is briefly described, it should be understood that the following drawings illustrates only some embodiments of the application, therefore is not construed as pair
The restriction of range for those of ordinary skill in the art without creative efforts, can also be according to this
A little attached drawings obtain the protection scope that other relevant attached drawings also belong to the application.
Fig. 1 is the first structure diagram of nucleic acid-extracting apparatus provided by the embodiments of the present application；
Fig. 2 is the second structural schematic diagram of nucleic acid-extracting apparatus provided by the embodiments of the present application；
Fig. 3 is the grafting cross-sectional view of bar magnet provided by the embodiments of the present application and magnetosheath；
Fig. 4 is the structural schematic diagram of magnetosheath locating rack provided by the embodiments of the present application；
Fig. 5 is the structural schematic diagram of bar magnet provided by the embodiments of the present application；
Fig. 6 is the enlarged drawing in Fig. 1 at VI；
Fig. 7 is the enlarged drawing in Fig. 1 at VII；
Fig. 8 is the enlarged drawing in Fig. 3 at VIII；
Fig. 9 is the attachment structure schematic diagram of bar magnet provided by the embodiments of the present application and bar magnet frame.
Icon: 100- bracket；The first driving assembly of 200-；The second driving assembly of 300-；400- bar magnet magnetosheath fit structure；
410- bar magnet frame；420- magnetosheath frame；430- magnetosheath locating rack；440- magnetosheath；450- magnetosheath mounting rack；The second auxiliary section 431-；
460- bar magnet；461- first end；462- second end；The first auxiliary section 421-；110- starting stave；The second riser of 120-；130-
Third riser；The first transverse slat of 140-；The second transverse slat of 150-；4211- positioning pin；4311- positioning sleeve；The first concaveconvex structure of 4212-；
The second concaveconvex structure of 4312-；411- mounting groove；4611- retention bead portion；4111- limits section；4112- necking section；412- first
Frame body；The second frame body of 413-.
Specific embodiment
To keep the purposes, technical schemes and advantages of the embodiment of the present application clearer, below in conjunction with the embodiment of the present application
In attached drawing, technical solutions in the embodiments of the present application is described.
Embodiment
Nucleic acid extraction separator mainly uses Beads enrichment technology to extract, the extraction of sample be by magnetosheath 440,
Bar magnet 460, magnetic bead cooperation extract.Between extraction, need that first bar magnet 460 is plugged in magnetosheath 440, then carry out sample
The extraction of product.
Fig. 1 is the first structure diagram of nucleic acid-extracting apparatus provided by the embodiments of the present application；Fig. 2 is the embodiment of the present application
Second structural schematic diagram of the nucleic acid-extracting apparatus of offer.Please refer to Fig. 1 and Fig. 2, in the present embodiment, nucleic acid extraction separator
Including nucleic acid-extracting apparatus.Nucleic acid-extracting apparatus includes bracket 100, the first driving assembly 200, the second driving assembly 300 and magnetic
Stick magnetosheath fit structure 400.
In the present embodiment, bar magnet magnetosheath fit structure 400 includes bar magnet frame 410, magnetosheath frame 420 and magnetosheath locating rack 430.
First driving assembly 200 and the second driving assembly 300 are all set in bracket 100, and the first driving assembly 200 is drivingly connected bar magnet frame
410, the second driving assembly 300 is drivingly connected magnetosheath frame 420.
As shown in the figure: the first driving assembly 200, which is drivingly connected bar magnet frame 410, makes bar magnet frame 410 move up and down, the second driving
Component 300, which is drivingly connected magnetosheath frame 420, makes magnetosheath frame 420 move up and down.
In the present embodiment, more magnetosheaths 440, the magnetosheath 440 on magnetosheath locating rack 430 are installed on magnetosheath locating rack 430
It is arranged in a row, nucleic acid-extracting apparatus further includes magnetosheath mounting rack 450, and multiple slots are provided on magnetosheath mounting rack 450, each to insert
A magnetosheath locating rack 430 is plugged in slot, and more magnetosheaths 440 are plugged in each slot.
Fig. 3 is the grafting cross-sectional view of bar magnet 460 and magnetosheath 440 provided by the embodiments of the present application, and Fig. 4 is the embodiment of the present application
The structural schematic diagram of the magnetosheath locating rack 430 of offer.Please refer to Fig. 1, Fig. 3 and Fig. 4, in the present embodiment, a magnetosheath locating rack
430 corresponding 8 magnetosheaths 440, correspondingly, the magnetosheath 440,9 of 6 magnetosheaths 440,7 can also be arranged in a magnetosheath locating rack 430
440,12 magnetosheaths 440 of magnetosheath etc..The second auxiliary section 431 is provided on magnetosheath locating rack 430.
More bar magnets 460 are installed, the bar magnet 460 on bar magnet frame 410 lines up multiple rows of, row's bar magnet 460 on bar magnet frame 410
The magnetosheath 440 on magnetosheath locating rack 430 that a corresponding slot plugs, the corresponding row's magnetosheath 440 of row's bar magnet 460, row's magnetic
The quantity of stick 460 is corresponding with the quantity of row's magnetosheath 440, piece bar magnet 460 of grafting in a magnetosheath 440.In the present embodiment,
Corresponding 8 bar magnets 460 of one row's bar magnet 460, correspondingly, 6 bar magnets, 460,7 bar magnets can also be arranged in a bar magnet frame 410
460,9 bar magnets, 460,12 bar magnets 460 etc..
In the present embodiment, it is provided with four row's bar magnets 460 on bar magnet frame 410, row's magnetosheath is provided on magnetosheath locating rack 430
440, a bar magnet frame 410 can correspond to 4 magnetosheath locating racks 430, the corresponding magnetosheath 440 of a bar magnet 460.
In the present embodiment, magnetosheath locating rack 430 is a positioning plate, is provided with multiple through-holes on positioning plate, on positioning plate
It is provided with more magnetosheaths 440, the corresponding magnetosheath 440 of a through-hole, that is to say, that magnetosheath 440 is provided on positioning plate, and fixed
A through-hole on the plate of position is corresponding with the magnetosheath hole of a magnetosheath 440.When bar magnet 460 is inserted into magnetosheath 440, bar magnet 460
It is first inserted into through-hole, is inserted into corresponding magnetosheath 440.
In the present embodiment, the both ends of positioning plate are provided with the second auxiliary section 431, that is to say, that positioning plate is stripe board, item
One row's magnetosheath 440 is installed, and the both ends of stripe board are provided with the second auxiliary section 431 on shape plate.
8 through-holes are provided on positioning plate, magnetosheath 440 is fixed on positioning plate, on the magnetosheath hole of magnetosheath 440 and positioning plate
Through-hole it is corresponding, magnetosheath hole is connected to through-hole, bar magnet 460 can pass through positioning plate on through-hole be plugged in magnetosheath 440.
Through-hole is provided on magnetosheath frame 420, optionally, magnetosheath frame 420 is correspondingly arranged on 4 exhausting holes, sets on bar magnet frame 410
4 row's bar magnets 460 are equipped with, after every row's bar magnet 460 is connect with bar magnet frame 410, across the through-hole of magnetosheath frame 420.That is, figure
5 be the structural schematic diagram of bar magnet 460 provided by the embodiments of the present application.Referring to Fig. 5, bar magnet 460 includes first end 461 and second
End 462, first end 461 is connect with bar magnet frame 410, and second end 462 sequentially passes through the through-hole of magnetosheath frame 420, the through-hole of positioning plate
It is plugged in magnetosheath 440.
In the present embodiment, magnetosheath frame 420 includes four parallel magnetosheath plates, and four magnetosheath plates are in the same plane, and four
A magnetosheath plate connects to form frame structure by connecting rod, is provided with an exhausting hole on each magnetosheath plate, and the second of bar magnet 460
End 462 sequentially passes through the through-hole of 440 plate of magnetosheath, the through-hole of positioning plate is plugged in magnetosheath 440.And through-hole, side is arranged in magnetosheath plate
Just the installation positioning of bar magnet 460, keeps magnetosheath 440 and the fiting effect of bar magnet 460 more preferable.
It is provided with the first auxiliary section 421 on magnetosheath frame 420, is provided with the first auxiliary section on 440 plate of magnetosheath of magnetosheath frame 420
421, the both ends of a magnetosheath plate are provided with the first auxiliary section 421, and a magnetosheath frame 420 can fix four magnetic with corresponding matching
Cover locating rack 430, wherein two the first auxiliary sections 421 and two the second auxiliary section 431 correspondences fix a magnetosheath locating rack
430, the quantity of the corresponding fixed magnetosheath locating rack 430 of magnetosheath frame 420 can be adjusted according to demand.
The side setting of the close magnetosheath locating rack 430 of 440 plate of magnetosheath is fluted, when the first auxiliary section 421 is matched with second
When the cooperation of conjunction portion 431 is fixed, positioning plate is fastened in the groove of 440 plate of magnetosheath, realizes magnetosheath frame 420 and magnetosheath locating rack
430 installation.
Bracket 100 includes starting stave 110, the second riser 120, third riser 130 and the first transverse slat 140, the second transverse slat
150, starting stave 110 and the second riser 120 and third riser 130 are vertically arranged, and starting stave 110 and the second riser
120 is vertical, and the second riser 120 is vertical with third riser 130, and starting stave 110 and third riser 130 are located at second and erect
It is perpendicular that the two sides of plate 120, the first transverse slat 140 and the second transverse slat 150 are connected to starting stave 110, the second riser 120 and third
The both ends of plate 130 form a box body structure with opening.
First driving assembly 200 and the second driving assembly 300 are all set in the outer surface of the second riser 120, bar magnet frame
410, magnetosheath frame 420 and magnetosheath locating rack 430 are respectively positioned in box body structure, and the first driving assembly 200 includes first motor, first
Screw rod, the first nut and the first fixing piece are provided with vertical slot on second riser 120, and first motor is fixed on
Two risers 120, the output shaft of first motor are drivingly connected the first screw rod, the first nut, the first fixing piece are arranged outside the first screw rod
The first nut is fixed in one end, and the other end passes through slot and is fixed on bar magnet frame 410.
First motor rotates forward, the rotation of the first screw rod, and the first nut is with rotation, since the first fixing piece limits the first nut
Rotation, so, the first nut linear motion, so that the bar magnet frame 410 being connected on the first fixing piece is moved downward, the first electricity
Machine reversion, bar magnet frame 410 move upwards.
Correspondingly, the second driving assembly 300 includes the second motor, the second screw rod, the second nut and the second fixing piece, described
Vertical slot is provided on second riser 120, the second motor is fixed on the second riser 120, the output shaft driving of the second motor
The second screw rod is connected, the second nut is arranged outside the second screw rod, the second nut is fixed in second fixing piece one end, and the other end passes through slot
Bar magnet frame 410 is fixed in hole.
Second motor rotates forward, the rotation of the second screw rod, and the second nut is with rotation, since the second fixing piece limits the second nut
Rotation, so, the second nut linear motion, so that the magnetosheath frame 420 being connected on the second fixing piece is moved downward, the second electricity
Machine reversion, magnetosheath frame 420 move upwards.
In other embodiments, the first driving assembly 200 and the second driving assembly 300 can also be motor, gear, rack gear
Structure or motor, rocking bar, slide block structure, to control bar magnet frame 410 and the up and down motion of magnetosheath frame 420.
Fig. 6 is the enlarged drawing in Fig. 1 at IV；Fig. 7 is the enlarged drawing in Fig. 1 at V；Fig. 8 is the enlarged drawing in Fig. 3 at VI.
Please refer to Fig. 1, Fig. 6-Fig. 8, in the present embodiment, when magnetosheath frame 420 and magnetosheath locating rack 430 slide in opposition, the first auxiliary section
421 and second the cooperation of auxiliary section 431 fix, when bar magnet frame 410 and magnetosheath locating rack 430 slide in opposition, bar magnet 460 is plugged in
In magnetosheath 440.
Wherein it is possible to which first motor and the second motor rotate forward, bar magnet frame 410 and magnetosheath frame 420 are moved downward, and make magnetic
The second end 462 of bar magnet 460 on stick frame 410 passes through the through-hole on positioning plate, is plugged in magnetosheath 440.And first auxiliary section
421 and second auxiliary section 431 cooperation fix, so that magnetosheath locating rack 430 be made to be fixedly mounted on magnetosheath frame 420.Then first
Motor and the second motor invert, and move upwards bar magnet frame 410 and bar magnet frame 410, take bar magnet 460.
In another way of example, the second motor is rotated forward, and magnetosheath frame 420 moves downward, and makes the first auxiliary section 421 and the
The cooperation of two auxiliary sections 431 is fixed, and magnetosheath frame 420 is fixed together with magnetosheath locating rack 430, and magnetosheath 440 is fixed on magnetosheath frame 420
On, the second motor reversal moves upwards magnetosheath frame 420, and the magnetosheath 440 being fixed together with magnetosheath frame 420 moves upwards, and makes
Magnetosheath 440 is set in outside bar magnet 460.
In another embodiment, first motor rotates forward, and bar magnet frame 410 moves downward, and bar magnet 460 is made to be plugged on magnetosheath
In magnetosheath 440 on locating rack 430, the second motor is rotated forward, and magnetosheath frame 420 moves downward, and matches the first auxiliary section 421 with second
The cooperation of conjunction portion 431 is fixed, and magnetosheath frame 420 is fixed together with magnetosheath locating rack 430, the second motor reversal, make magnetosheath frame 420 to
Upper movement, first motor reversion, moves upwards bar magnet frame 410, to realize taking for magnetosheath 440.
In the present embodiment, the lower end of magnetosheath 440 is enclosed construction, when needing to remove magnetosheath 440, bar magnet frame
410 move downward, and bar magnet 460 is made to push up the lower end of magnetosheath 440, to keep the first auxiliary section 421 and the second auxiliary section 431 de-
From, it will be able to so that magnetosheath locating rack 430 is detached from magnetosheath frame 420, so that magnetosheath 440 be removed, keeps exiting for magnetosheath 440 more square
Just.
In the present embodiment, it is additionally provided with the first fan and the second fan on third riser 130, passes through the first fan and second
The effect of fan can dry up the liquid being infected on magnetosheath 440, and can will extract the gaseous pollutant generated and take away extraction
Region prevents from polluting, and avoids the extraction for influencing sample.
Please continue to refer to Fig. 6-Fig. 8, in the present embodiment, the first auxiliary section 421 is positioning pin 4211, the second auxiliary section 431
For positioning sleeve 4311, positioning pin 4211 is plugged in positioning sleeve 4311 to be fixed with the cooperation of positioning sleeve 4311.That is: positioning plate
Both ends be provided with positioning sleeve 4311, the both ends of 440 plate of magnetosheath are provided with positioning pin 4211, the axis of two positioning pins 4211
The distance between the distance between line and the axis of two positioning sleeves 4311 are consistent, and a positioning pin 4211 is inserted in a positioning
In set 4311, magnetosheath locating rack 430 is fixed.When needing to exit magnetosheath 440, first motor rotating forward is directly controlled, is made
Bar magnet 460 moves downward, the effect to the lower end applied force of magnetosheath 440, to make positioning pin 4211 from positioning sleeve 4311
It is detached from, magnetosheath 440 is exited.
In the present embodiment, positioning sleeve 4311 can be the structure formed on magnetosheath locating rack 430 by mould punching, with
The cooperation of positioning pin 4211 is fixed.
In other embodiments, the first auxiliary section 421 is positioning sleeve 4311, and the second auxiliary section 431 is positioning pin 4211, fixed
Position set 4311 is sheathed on outside positioning pin 4211 and the cooperation of positioning pin 4211 is fixed.That is: the both ends of positioning plate are provided with
Positioning pin 4211, the both ends of 440 plate of magnetosheath are provided with positioning sleeve 4311, the distance between axis of two positioning sleeves 4311 with
The distance between axis of two positioning pins 4211 is consistent, and a positioning pin 4211 is inserted in a positioning sleeve 4311, to magnetic
Set locating rack 430 is fixed.When needing to exit magnetosheath 440, first motor rotating forward is directly controlled, transports bar magnet 460 downwards
It is dynamic, the effect to the lower end applied force of magnetosheath 440, to make positioning pin 4211 be detached from from positioning sleeve 4311, by magnetosheath 440
It exits.
In order to keep the cooperation fixed effect between positioning pin 4211 and positioning sleeve 4311 more preferable, and using bar magnet 460 to magnetic
When covering the effect of 440 applied forces, magnetosheath 440 is also easy to exit.The outer peripheral surface of positioning pin 4211 is provided with the first concave-convex knot
Structure 4212, the inner peripheral surface of positioning sleeve 4311 are provided with the second concaveconvex structure 4312, the first concaveconvex structure 4212 and the second concave-convex knot
Structure 4312 is engaged by clamping.It is interference fitted between positioning sleeve 4311 and positioning pin 4211, positioning pin 4211 and positioning sleeve can be made
Cooperation is fixedly mounted and when effect by power between 4311, and positioning pin 4211 can be made to be detached from positioning sleeve 4311.
First concaveconvex structure 4212 is set as protrusion, and the second concaveconvex structure 4312 is set as being engaged by clamping with protrusion recessed
Slot.Or first concaveconvex structure 4212 be set as groove, the second concaveconvex structure 4312 is set as the protrusion being engaged by clamping with groove.It is real
Secure fit between existing magnetosheath frame 420 and magnetosheath locating rack 430.
In the present embodiment, be arranged on positioning sleeve 4311 it is jagged, when positioning pin 4211 be inserted into positioning sleeve 4311 in when,
Due to the notch of the first concaveconvex structure 4212 and positioning sleeve 4311 on positioning pin 4211, the internal diameter of positioning sleeve 4311 can be made to become
Greatly, positioning pin 4211 is squeezed into positioning sleeve 4311, the first concaveconvex structure 4212 and the cooperation of the second concaveconvex structure 4312 exist
Together, the rebound of positioning sleeve 4311 is original shape, so that positioning sleeve 4311 and positioning pin 4211 is engaged by clamping, realizes magnetosheath frame
Fixation between 420 and magnetosheath locating rack 430.
Fig. 9 is the attachment structure schematic diagram of bar magnet 460 and bar magnet frame 410 provided by the embodiments of the present application.Referring to Fig. 9,
In the present embodiment, mounting groove 411 is provided on bar magnet frame 410, first end 461 is located in mounting groove 411, and bar magnet 460 is opposite
It is slidably connected in bar magnet frame 410 along the radial direction of bar magnet 460, bar magnet 460 is connect to limit with 410 axial limiting of bar magnet frame
One end 461 falls off from the notch of mounting groove 411, and second end 462 is for being plugged in magnetosheath 440.Do not need to bar magnet 460 into
Row is accurately installed, and the error that can be installed with some also can be realized the cooperation of bar magnet 460 Yu magnetosheath 440.
Stop bosses 4611 are arranged in first end 461, and magnetic is protruded along the radial direction of bar magnet 460 in retention bead portion 4611
The outer peripheral surface of stick 460；Mounting groove 411 has limit section 4111 and necking section 4112, and limit section 4111 and necking section 4112 connect
Logical, the internal diameter of necking section 4112 is less than the internal diameter of limit section 4111, and retention bead portion 4611 is located at limit section 4111, second end
462 stretch out from necking section 4112.After bar magnet 460 is inserted into magnetosheath 440, bar magnet 460 can be along magnetic in limit section 4111
The radial direction of stick 460 is mobile, and the bar magnet 460 for not needing high assembly precision can be realized as between bar magnet 460 and magnetosheath 440
Installation.
Bar magnet frame 410 includes the first frame body 412 and the second frame body 413, is provided with mounting hole on the first frame body 412, the
Two frame bodies 413 are installed on the first frame body 412, and the Single port of the second frame body 413 capping mounting hole, the first frame body 412 and the
Two frame bodies 413 limit mounting groove 411 jointly at mounting hole.
When needing to install bar magnet 460, the second end 462 of bar magnet 460 is inserted into the second of mounting hole and bar magnet 460
Mounting hole is exposed at end 462, and the retention bead portion 4611 of first end 461 is located in mounting hole.Pass through the second frame body 413 capping peace again
Hole is filled, limiting bar magnet 460 can move in the vertical direction in mounting hole, be fixed on bar magnet 460 on bar magnet frame 410, magnetic
Stick 460 will not be detached from bar magnet frame 410 from mounting hole, due to the retention bead portion 4611 of first end 461 and the hole wall of mounting hole
Between have gap, can produce small shaking, bar magnet 460 preferably slided inside magnetosheath 440, will not
Since the error processed and assembled causes bar magnet 460 to be stuck in magnetosheath 440, it will not cause bar magnet 460 that magnetosheath 440 is missed roof fall
The phenomenon that getting off.In the present embodiment, the end of the separate first end 461 of the second end 462 of bar magnet 460 is chamfering structure, also
It is to say, the second end 462 of bar magnet 460 is thin-walled hollow round tube, or the thin wall cylindrical of drilling, is filled in inside one high magnetic
Oval magnet, and hollow circular-tube 1mm is stretched out in the end of magnet, so that magnet and hollow circular-tube is formed step structure, stretches out open circles
The end of pipe is an end of internal oval magnet, so that the end of bar magnet 460 is generated ferromagnetism, and be inserted into magnetic to bar magnet 460
Set 440 has guiding role, so that bar magnet 460 smoothly introduces in magnetosheath 440, realizes the installation of bar magnet 460.
Magnetosheath 440 takes method, is suitable for above-mentioned bar magnet magnetosheath fit structure 400, the method for taking includes: magnetosheath frame
420 is mobile towards the direction of magnetosheath locating rack 430, and the first auxiliary section 421 and the cooperation of the second auxiliary section 431 are fixed, and determines magnetosheath
Position frame 430 is fixed on magnetosheath frame 420.Bar magnet frame 410 is mobile towards the direction of magnetosheath locating rack 430, and bar magnet 460 is made to be plugged in magnetic
In set 440, wherein a bar magnet 460 is plugged in a magnetosheath 440.Realize magnetosheath 440 installation with take.
In the present embodiment, magnetosheath 440 takes method, is suitable for above-mentioned nucleic acid-extracting apparatus, and the method for taking includes:
(1), first motor and the second motor rotate forward, and bar magnet frame 410 and magnetosheath frame 420 move downward, and make bar magnet 460
It is inserted into magnetosheath 440, the positioning pin 4211 on magnetosheath frame 420 is inserted into the positioning sleeve 4311 on magnetosheath locating rack 430, makes magnetosheath
Locating rack 430 is fixed on magnetosheath frame 420.
(2), first motor and the second motor invert, and move upwards bar magnet frame 410 and magnetosheath frame 420, make and magnetic
The magnetosheath locating rack 430 that stock 420 is installed also moves upwards, and realizes taking for magnetosheath 440.
(3), after bar magnet 460 and magnetosheath 440 use completion, first motor is rotated forward, and bar magnet frame 410 moves downward, bar magnet
The end of 460 second end 462 applies the effect of downward power to the lower end of magnetosheath 440, makes bar magnet 460 to magnetosheath locating rack
The effect of 430 applied forces, makes positioning pin 4211 be detached from positioning sleeve 4311, and magnetosheath frame 420 is separated with magnetosheath locating rack 430.
(4), the second motor reversal, bar magnet frame 410 move upwards, and exit magnetosheath 440.
The foregoing is merely preferred embodiment of the present application, are not intended to limit this application, for the skill of this field
For art personnel, various changes and changes are possible in this application.Within the spirit and principles of this application, made any to repair
Change, equivalent replacement, improvement etc., should be included within the scope of protection of this application.
Claims (10)
1. a kind of bar magnet magnetosheath fit structure characterized by comprising
The bar magnet frame of more bar magnets is installed；
Magnetosheath frame is provided with the first auxiliary section on the magnetosheath frame；
The magnetosheath locating rack of the more magnetosheaths is installed, is provided with the second auxiliary section on the magnetosheath locating rack；
When the magnetosheath frame and the magnetosheath locating rack slide in opposition, first auxiliary section and second auxiliary section cooperate
Fixed, when the bar magnet frame slides in opposition with the magnetosheath locating rack, the bar magnet is plugged in the magnetosheath.
2. bar magnet magnetosheath fit structure according to claim 1, which is characterized in that first auxiliary section is positioning pin,
Second auxiliary section is positioning sleeve, and the positioning pin is plugged in the positioning sleeve to be fixed with positioning sleeve cooperation.
3. bar magnet magnetosheath fit structure according to claim 1, which is characterized in that first auxiliary section is positioning sleeve,
Second auxiliary section is positioning pin, and the positioning sleeve is sheathed on outside the positioning pin and fixes with the detent fit.
4. according to bar magnet magnetosheath fit structure described in claim 2 or 3, which is characterized in that the outer peripheral surface of the positioning pin
It is provided with the first concaveconvex structure, the inner peripheral surface of the positioning sleeve is provided with the second concaveconvex structure, first concaveconvex structure and institute
State the clamping engagement of the second concaveconvex structure.
5. bar magnet magnetosheath fit structure according to claim 4, which is characterized in that first concaveconvex structure is set as convex
It rises, second concaveconvex structure is set as the groove being engaged by clamping with the protrusion.
6. bar magnet magnetosheath fit structure according to claim 1, which is characterized in that the bar magnet includes first end and second
It holds, is provided with mounting groove on the bar magnet frame, the first end is located in the mounting groove, and the bar magnet is relative to the magnetic
Stick frame is slidably connected along the radial direction of the bar magnet, and the bar magnet is connect to limit described with the bar magnet frame axial limiting
One end falls off from the notch of the mounting groove, and the second end is for being plugged in the magnetosheath.
7. bar magnet magnetosheath fit structure according to claim 6, which is characterized in that the first end is provided with retention bead
The outer peripheral surface of the bar magnet is protruded in portion, the retention bead portion along the radial direction of the bar magnet；The mounting groove has limit
Section and necking section, the limit section are connected to the necking section, and the internal diameter of the necking section is less than the internal diameter of the limit section,
The retention bead portion is located at the limit section, and the second end is stretched out from the necking section.
8. bar magnet magnetosheath fit structure according to claim 6 or 7, which is characterized in that the bar magnet frame includes first
Body and the second frame body, are provided with mounting hole on first frame body, second erection of frames on first frame body, and
Second frame body covers the Single port of the mounting hole, and first frame body and second frame body are total at the mounting hole
It is same to limit the mounting groove.
9. any one of a kind of nucleic acid-extracting apparatus, including bracket, the first driving assembly, the second driving assembly and claim 1-8
The bar magnet magnetosheath fit structure, first driving assembly and second driving assembly are all set in the bracket, institute
It states the first driving assembly and is drivingly connected the bar magnet frame, second driving assembly is drivingly connected the magnetosheath frame.
10. a kind of magnetosheath takes method, which is characterized in that match suitable for the described in any item bar magnet magnetosheaths of claim 1-8
Structure is closed, the method for taking includes:
The magnetosheath frame is mobile towards the direction of the magnetosheath locating rack, and first auxiliary section and second auxiliary section cooperate
It is fixed, so that the magnetosheath locating rack is fixed on the magnetosheath frame；
The bar magnet frame is mobile towards the direction of the magnetosheath locating rack, is plugged in the bar magnet in the magnetosheath, wherein one
Root bar magnet is plugged in the magnetosheath.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910186909.3A CN109706058A (en) | 2019-03-12 | 2019-03-12 | Bar magnet magnetosheath fit structure, nucleic acid-extracting apparatus and magnetosheath take method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910186909.3A CN109706058A (en) | 2019-03-12 | 2019-03-12 | Bar magnet magnetosheath fit structure, nucleic acid-extracting apparatus and magnetosheath take method |
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| CN109706058A true CN109706058A (en) | 2019-05-03 |
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| CN201910186909.3A Pending CN109706058A (en) | 2019-03-12 | 2019-03-12 | Bar magnet magnetosheath fit structure, nucleic acid-extracting apparatus and magnetosheath take method |
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| CN115232808A (en) * | 2022-06-09 | 2022-10-25 | 通用生物(安徽)股份有限公司 | Preparation device and application of novel magnetic bead method purified DNA (deoxyribonucleic acid) matching reagent |
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