CN109700995A - A kind of pharmaceutical composition and preparation method thereof for treating peptic ulcer - Google Patents
A kind of pharmaceutical composition and preparation method thereof for treating peptic ulcer Download PDFInfo
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Abstract
The invention discloses a kind of pharmaceutical compositions and preparation method thereof for treating peptic ulcer, and the composition includes the following raw material: Radix Aconiti Lateralis Preparata, gun ginger, radix glycyrrhizae preparata, ginseng, Rhizoma Atractylodis Macrocephalae, Cortex Magnoliae Officinalis, Radix Astragali, wrinkled giant hyssop, cuttle bone, excrementum pteropi, cornu cerve degelatinatum, fish glue, Radix Notoginseng, fritillaria thunbergii, aspongopus, Rheum palmatum (processed with wine) and evodia rutaecarpa.Pharmaceutical composition of the invention can be effectively solved, etiology and pathogenesis and symptom, and uneasy to recur, be free from side effects after taking, embody Chinese medicine letter, just, honest and clean and studying from nature core concept.
Description
Technical field
The invention belongs to pharmaceutical technology fields, and in particular to a kind of pharmaceutical composition and its preparation for treating peptic ulcer
Method.
Background technique
Peptic ulcer is common in stomach and duodenum, because ulcer formation is related with gastric acid/pepsin digestion
And it gains the name.Pathogenesis: 1. Helicobacter pylori infections.2. applying non-steroidal anti-inflammatory drugs.3. gastric acid and pepsin are to mucous membrane
Autodigestion.4. other factors (1. smokings.2. heredity.3. acute stress.4. gastroduodenal dyskinesia.)；Clinical symptoms
Using: epigastric pain as cardinal symptom, property can be dull pain, cusalgia, distending pain, severe pain or hungry sample sense of discomfort, be often accompanied by sour regurgitation,
The symptoms such as gas, big belly.Multidigit, can be to the right or to the left in middle upper abdomen.Generally mild to moderate persistent ache.Pain has typical case more
Rhythmicity, gastric ulcer pain two meal between (hunger pain), food after alleviate；Duodenal ulcer is to send out for postprandial about one hour
It is raw, alleviated through 1-2 hours, until repeating the above-mentioned rhythm and pace of moving things after meal feed next time.At midnight can occur for some patientss pain (night
Bitterly), gastric ulcer is more common.Epigastric pain can often be alleviated after taking antacids；It can bleeding, perforation, pyloric stenosis, canceration.It controls
It treats with gastric acid inhibitory, keep gastric mucosa, anti-helicobacter pylori, deactivated non-steroidal anti-inflammatory drugs and surgical operation therapy.
By Western medicine (drugs such as ranitidine, thiosugar aluminium flake, Omeprazole, clarithromycin) treat, but its side effect compared with
Greatly and easily recurrent exerbation, only anti symptom treatment；Belong to its " stomachache " scope of Chinese medicine, pathogenic factor is mainly due to diet is not
When, tremble with fear caused by dim imbalance, liver-stomach disharmony, deficiency-cold in spleen and stomach, qi and blood stagnation.
For these reasons, the present invention is specifically proposed.
Summary of the invention
In order to solve problem above of the existing technology, the present invention provides a kind of medicine groups for treating peptic ulcer
Object and preparation method thereof is closed, Chinese medicine composition of the invention can effectively solve the problem that its etiology and pathogenesis and symptom, and uneasy to recur, nothing
Side effect, embody Chinese medicine letter, just, honest and clean and studying from nature core concept.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of pharmaceutical composition for treating peptic ulcer, the composition includes the following raw material: Radix Aconiti Lateralis Preparata, big gun are dry
Ginger, radix glycyrrhizae preparata, ginseng, Rhizoma Atractylodis Macrocephalae, Cortex Magnoliae Officinalis, Radix Astragali, wrinkled giant hyssop, cuttle bone, excrementum pteropi, cornu cerve degelatinatum, fish glue, Radix Notoginseng, fritillaria thunbergii, nine
Fragrant worm, Rheum palmatum (processed with wine) and evodia rutaecarpa.
Further, according to parts by weight, the composition includes the following raw material: Radix Aconiti Lateralis Preparata 60-90 parts by weight, gun ginger
25-45 parts by weight, radix glycyrrhizae preparata 20-30 parts by weight, ginseng 18-30 parts by weight, Rhizoma Atractylodis Macrocephalae 15-45 parts by weight, Cortex Magnoliae Officinalis 18-35 weight
Part, Radix Astragali 60-150 parts by weight, wrinkled giant hyssop 25-30 parts by weight, cuttle bone 15-30 parts by weight, excrementum pteropi 15-30 parts by weight, deer horn
White 18-30 parts by weight, fish glue 15-30 parts by weight, Radix Notoginseng 8-20 parts by weight, fritillaria thunbergii 15-30 parts by weight, aspongopus 18-30
Parts by weight, Rheum palmatum (processed with wine) 15-25 parts by weight and evodia rutaecarpa 15-45 parts by weight.
Further, according to parts by weight, the composition includes the following raw material: Radix Aconiti Lateralis Preparata 70-80 parts by weight, gun ginger
30-40 parts by weight, radix glycyrrhizae preparata 23-27 parts by weight, ginseng 22-26 parts by weight, Rhizoma Atractylodis Macrocephalae 25-35 parts by weight, Cortex Magnoliae Officinalis 24-29 weight
Part, Radix Astragali 100-110 parts by weight, wrinkled giant hyssop 27-28 parts by weight, cuttle bone 20-25 parts by weight, excrementum pteropi 20-25 parts by weight, deer horn
White 22-26 parts by weight, fish glue 20-25 parts by weight, Radix Notoginseng 12-16 parts by weight, fritillaria thunbergii 20-25 parts by weight, aspongopus 22-26
Parts by weight, Rheum palmatum (processed with wine) 18-22 parts by weight and evodia rutaecarpa 28-32 parts by weight.
Further, according to parts by weight, the composition includes the following raw material: 75 parts by weight of Radix Aconiti Lateralis Preparata, gun ginger 35
Parts by weight, 25 parts by weight of radix glycyrrhizae preparata, 24 parts by weight of ginseng, 30 parts by weight of Rhizoma Atractylodis Macrocephalae, 26.5 parts by weight of Cortex Magnoliae Officinalis, 105 parts by weight of Radix Astragali,
27.5 parts by weight of wrinkled giant hyssop, 22.5 parts by weight of cuttle bone, 22.5 parts by weight of excrementum pteropi, 24 parts by weight of cornu cerve degelatinatum, 22.5 weight of fish glue
Measure part, 14 parts by weight of Radix Notoginseng, 22.5 parts by weight of fritillaria thunbergii, 30 weight of 24 parts by weight of aspongopus, 20 parts by weight of Rheum palmatum (processed with wine) and evodia rutaecarpa
Measure part.
Heretofore described Radix Aconiti Lateralis Preparata is that unprocessed Radix Aconiti Lateralis adds decocting 1-3 hours, is dried spare.Radix Aconiti Lateralis Preparata is rescued with Hui Yang
It is inverse, go out certainly for yang depletion syndrome symptoms include cold sweat, cold limbs, feeble and impalpable pulse.Mends fire supporing yang mends fire, exactly mends fire from the gater of life, orders
The fire of door is exactly Yuanyang, the kidney yang of human body.Eliminating cold to stop pain, can middle benefit gas, and can Wen Jing.
During gun ginger mainly warms up, recover Yang and smooth venation, warming spleen and stomach for dispelling cold, warming lung and resolving fluid.For treatment excessive, the Han Xiezhi that eats cold drink
It taps into vivo, the day that rains heavily drops down water, and cold-evil is from lower and enter.
Radix glycyrrhizae preparata primary efficacy is and middle emergency, moistening lung are detoxified, coordinating the drug actions of a prescription.It is usually used in weakness of the spleen and the stomach, fatigue and weakness,
Severe palpilation, knotted pulse, detachable son poison.
The strong tonic of ginseng is suitable for adjustment blood pressure, restores cardiac function, neurasthenia and the diseases such as in poor health,
There are eliminating the phlegm, stomach invigorating, diuresis, excitement and other effects.
Rhizoma Atractylodis Macrocephalae strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.For spleen eating less, abdominal distention diarrhea, the diseases such as threatened abortion.
Cortex Magnoliae Officinalis dispelling dampness with bitter and warm-natured drugs medicine is used for damp retention in middle-jiao, and effect is very strong, but its master of ceremonies's effect should be promoting the circulation of qi, more than eliminating dampness
Important, its optimal classification should be qi-activating drug, it has conspiracy relation with grey.Promoting the circulation of qi main portions are stomach and intestine, also include lung channel.Effect
Fruit is mainly dissipate-swelling, eliminates abdominal fullness and distention or abdominal distension caused by gas product blocks, promoting the circulation of qi dissipate-swelling is most strong, all stomach and intestine stagnation of the circulation of vital energys, swollen
It is full, regardless of cold and heat and asthenia and sthenia.
Radix Astragali its there is enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial to make
With.But the real evil Sheng of table, retention of dampness due to stagnation of QI, dyspepsia are stagnated.
Wrinkled giant hyssop is eliminated dampness with aromatics and middle preventing or arresting vomiting, delivers relieving summer-heat.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian is vomitted, summer-heat and damp exterior syndrome, at the beginning of damp-warm syndrome
It rises, burnout of generating heat is uncomfortable in chest not relax, and cold-dampness closes heat, and abdominal pain is vomited and diarrhoea, nasosinusitis headache.
This Chinese medicine taste of cuttle bone cuttle bone is salty and puckery, but property is mild, have astringing to arrest bleeding and treating spontaneous emission and leukorrhagia and
There are also the multiple efficacies such as sore for analgesic, usually it can be used for mankind's spitting blood and haematemesis and hematochezia there are also kidney deficiency and stomachache and
The treatment of the common diseases such as eczema, both oral administration can also external application when treatment.
Excrementum pteropi promoting blood circulation to remove blood stasis, fries charcoal hemostasis.For trusted subordinate's extravasated blood, dysmenorrhea, blood stasis, postpartum congestion and abdominal pain；
Fry charcoal and control metrostaxis；Traumatic injury, snake, insect bite are controlled in external application.
Cornu cerve degelatinatum has the effect of warming kidney and enhancing yang, astringing to arrest bleeding.It is usually used in the insufficiency of both the spleen and the kindey, leukorrhea, enuresis frequent micturition collapses
The treatment for the illnesss such as leak down blood, and sore is not held back.
Fish glue has the effect of nourishing liver and kidney, nourishing blood and hemoslasis, eliminating stasis to subdue swelling.It is usually used in emission due to the kidney deficiency, waist-leg weakness, waist
Bitterly, dizziness and tinnitus, leukorrhea, habitual abortion, ischemic spasm, puerperal exposure to wind convulsion, tetanus, epilepsy, alpastic anemia are spat
Blood, hemoptysis, hematuria, metrorrhagia and metrostaxis, traumatic hemorrhage, negative subcutaneous ulcer, fistula, chronic ulcer, chap, gout, hemorrhoid.
Radix Notoginseng dissipating stasis and stanching bleeding, detumescence ding-tong.For spitting blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen shouting pain,
Tumbling and swelling.
Fritillaria thunbergii clearing heat and eliminating phlegm；Open strongly fragrant dissipating bind.
Aspongopus regulating qi-flowing for relieving pain, middle benefit gas are supporing yang.For stomach cold distending pain, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach, impotence due to deficiency of the kidney, soreness of waist and knee joint.
Rheum palmatum (processed with wine), which has, attacks stagnant, clearing away damp-heat, purging intense heat, cool blood, dissolving stasis, removing toxic substances and other effects.
Its property heat of evodia rutaecarpa is bitterly, has the function of eliminating cold to stop pain, stopping nausea and vomiting by lowering the adverse flow of QI, for treating deficiency cold of liver and stomach, overcast and turbid ascending and descending
The diseases such as caused headache or gastral cavity pain.
Further, the pharmaceutical composition also includes pharmaceutically acceptable auxiliary material or carrier, preferably pill,
Capsule or decoction.
A kind of preparation method of the pharmaceutical composition of the treatment peptic ulcer, the method include following step
It is rapid:
(1) each raw material is weighed according to formula rate, is ground into fine powder respectively, then carry out uniformly mixed, obtain traditional Chinese medicine powder；
(2) medically acceptable auxiliary material or carrier is added in the traditional Chinese medicine powder and pharmaceutical dosage form is made.
Further, the pharmaceutical composition is pill, and auxiliary material is fecula and water.
Further, the diameter of the pill is 3-5mm.
Further, the mass ratio of traditional Chinese medicine powder, fecula and water is 9-11:1-3:4-6, preferably 10:2:5.
Further, fecula is mealy potato, can be commercially available on the market or the fecula is sweet potato powder, rice flour
Deng.
Further, the pharmaceutical composition is capsule, every 0.75g containing traditional Chinese medicine powder.
Wherein, the shell of capsule uses commercially available raw material.
Further, composition of the invention is decoction.
Further, each medicinal material is uniformly mixed by the production method of decoction, in addition the water of 1800-2200 parts by weight, impregnates
35-45 minutes, then first pass, first boiled with strong fire, the small fire timing in tune, decocted 35-45 minutes, obtained medical fluid 180-220 weight
Part is measured, is poured out, adds the decocting of 900-1100 parts by weight 25-35 minutes again in the dregs of a decoction, obtains medical fluid 180-220 parts by weight.By two
It mixes all over medical fluid, is taking after morning and evening dinner respectively.
Acute stage, gives decoction treatment (imitating macro because power is violent), and paracmasis and convalescence with former Fang Erzhi triplication, grind
It is broken to powdery, partial size is 80-100 mesh, and each 9g takes with warm water 2 times a day, 49 days as a treatment course.
Compared with prior art, beneficial effects of the present invention are as follows:
Pharmaceutical composition of the invention can be effectively solved, etiology and pathogenesis and symptom, and uneasy to recur, take rear nothing
Side effect, embody Chinese medicine letter, just, honest and clean and studying from nature core concept；The main mechanism of action is Radix Aconiti Lateralis Preparata, gun ginger, Wu
The fruit of medicinal cornel to help positive warming spleen and stomach for dispelling cold, ginseng, Radix Astragali, Rhizoma Atractylodis Macrocephalae with air making-up and spleen enlivening torr sore myogenic, Cortex Magnoliae Officinalis, aspongopus, Radix Notoginseng, radix glycyrrhizae preparata,
Wrinkled giant hyssop, Rheum palmatum (processed with wine) with sending down abnormally ascending warm up liver stomach function regulating promoting blood circulation, removing blood stasis and relieving pain and it is logical under (weed out the old and bring forth the new, because of the six hollow viscera must keep its unobstructed, stomach is liked to be reduced to
With), excrementum pteropi, cuttle bone, cornu cerve degelatinatum, fish glue are stopped blooding repairing ulcer face with warm stomach hyperacidity and pain relief, are assisted between each Chinese medicine material
Same-action has the function that help the logical lower repairing ulcer face of positive warming spleen and stomach for dispelling cold vital energy regualting and blood circulation-promoting analgesic.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below
Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work
Other embodiment belongs to the range that the present invention is protected.
Embodiment 1
A kind of pharmaceutical composition for treating peptic ulcer, the composition includes the following raw material: Radix Aconiti Lateralis Preparata 60g, big gun
Rhizoma zingiberis 25g, radix glycyrrhizae preparata 20g, ginseng 18g, Rhizoma Atractylodis Macrocephalae 15g, Cortex Magnoliae Officinalis 18g, Radix Astragali 60g, wrinkled giant hyssop 25g, cuttle bone 15g, excrementum pteropi
15g, cornu cerve degelatinatum 18g, fish glue 15g, Radix Notoginseng 8g, fritillaria thunbergii 15g, aspongopus 18g, Rheum palmatum (processed with wine) 15g and evodia rutaecarpa 15g.
The pharmaceutical composition of the present embodiment is pill, the preparation method is as follows:
(1) each raw material is weighed according to formula rate, is ground into fine powder respectively, then carry out uniformly mixed, obtain traditional Chinese medicine powder；
(2) traditional Chinese medicine powder, mealy potato and water are mixed according to mass ratio 10:2:5, pellet processing machine is made diameter and is
The pill of 4mm, as pill.
Embodiment 2
A kind of pharmaceutical composition for treating peptic ulcer, the composition includes the following raw material: Radix Aconiti Lateralis Preparata 70g, big gun
Rhizoma zingiberis 30g, radix glycyrrhizae preparata 23g, ginseng 22g, Rhizoma Atractylodis Macrocephalae 25g, Cortex Magnoliae Officinalis 24g, Radix Astragali 100g, wrinkled giant hyssop 27g, cuttle bone 20g, excrementum pteropi
20g, cornu cerve degelatinatum 22g, fish glue 20g, Radix Notoginseng 12g, fritillaria thunbergii 20g, aspongopus 22g, Rheum palmatum (processed with wine) 18g and evodia rutaecarpa 28g.
The pharmaceutical composition of the present embodiment is pill, the preparation method is as follows:
(1) each raw material is weighed according to formula rate, is ground into fine powder respectively, then carry out uniformly mixed, obtain traditional Chinese medicine powder；
(2) traditional Chinese medicine powder, mealy potato and water are mixed according to mass ratio 9:1:4, pellet processing machine is made diameter and is
The pill of 5mm, as pill.
Embodiment 3
A kind of pharmaceutical composition for treating peptic ulcer, the composition includes the following raw material: Radix Aconiti Lateralis Preparata 75g, big gun
Rhizoma zingiberis 35g, radix glycyrrhizae preparata 25g, ginseng 24g, Rhizoma Atractylodis Macrocephalae 30g, Cortex Magnoliae Officinalis 26.5g, Radix Astragali 105g, wrinkled giant hyssop 27.5g, cuttle bone 22.5g, five
Clever rouge 22.5g, cornu cerve degelatinatum 24g, fish glue 22.5g, Radix Notoginseng 14g, fritillaria thunbergii 22.5g, aspongopus 24g, Rheum palmatum (processed with wine) 20g and Wu Zhu
Cornel 30g.
The pharmaceutical composition of the present embodiment is pill, the preparation method is as follows:
(1) each raw material is weighed according to formula rate, is ground into fine powder respectively, then carry out uniformly mixed, obtain traditional Chinese medicine powder；
(2) traditional Chinese medicine powder, mealy potato and water are mixed according to mass ratio 11:3:6, pellet processing machine is made diameter and is
The pill of 3mm, as pill.
Embodiment 4
A kind of pharmaceutical composition for treating peptic ulcer, the composition includes the following raw material: Radix Aconiti Lateralis Preparata 80g, big gun
Rhizoma zingiberis 40g, radix glycyrrhizae preparata 27g, ginseng 26g, Rhizoma Atractylodis Macrocephalae 35g, Cortex Magnoliae Officinalis 29g, Radix Astragali 110g, wrinkled giant hyssop 28g, cuttle bone 25g, excrementum pteropi
25g, cornu cerve degelatinatum 26g, fish glue 25g, Radix Notoginseng 16g, fritillaria thunbergii 25g, aspongopus 26g, Rheum palmatum (processed with wine) 22g and evodia rutaecarpa 32g.
The pharmaceutical composition of the present embodiment is capsule, the preparation method is as follows:
(1) each raw material is weighed according to formula rate, is ground into fine powder respectively, then carry out uniformly mixed, obtain traditional Chinese medicine powder；
(2) it by the traditional Chinese medicine powder, is fitted into capsule shells, 0.75g containing traditional Chinese medicine powder in every capsule.
Embodiment 5
A kind of pharmaceutical composition for treating peptic ulcer, the composition includes the following raw material: Radix Aconiti Lateralis Preparata 90g, big gun
Rhizoma zingiberis 45g, radix glycyrrhizae preparata 30g, ginseng 30g, Rhizoma Atractylodis Macrocephalae 45g, Cortex Magnoliae Officinalis 35g, Radix Astragali 150g, wrinkled giant hyssop 30g, cuttle bone 30g, excrementum pteropi
30g, cornu cerve degelatinatum 30g, fish glue 30g, Radix Notoginseng 20g, fritillaria thunbergii 30g, aspongopus 30g, Rheum palmatum (processed with wine) 25g and evodia rutaecarpa 45g.
The pharmaceutical composition of the present embodiment is decoction, the preparation method is as follows:
Each medicinal material is uniformly mixed, in addition the water of 2000g impregnates 40 minutes, then first pass, is first boiled with strong fire, in tune
Small fire timing decocts 40 minutes, obtains medical fluid 200g, pour out, and adds 1000g decocting 30 minutes again in the dregs of a decoction, obtains medical fluid 200g,
Twice of fried obtained medical fluid is mixed, the decoction is obtained.
Test example 1
Lee, male, 42 years old, uncomfortable and gastral cavilty has a dull ache, when oral Omeprazole and colloidal bismuth pectin in its stomach after food
After alleviate, because classmate party drink after, its stomachache more very, spitting blood, stool be tarry stools, go hospital gastroscope to show: stomach 12 refer to
Enterelcosis is given to the ill and the treatment of antiacid protection stomach lining, after a week symptom improvement after half a year and because of improper diet anger and is drunk
Occur stomachache, vomiting, slightly hematochezia again after drinking, it is not good enough to take orally antiacid protection stomach lining medicine its curative effect, and chronognosis gastral cavilty is cold, trick ice
Dilute, diagnosis and treatment of coming out of admiration for a famous person when dry when cold, out of strength, acid regurgitation, stool: being for deficiency-cold in spleen and stomach, insufficiency of spleen-YNAG, qi and blood stagnation: control with
Help positive middle benefit gas, vital energy regualting and blood circulation-promoting, hyperacidity and pain relief.Give the decoction treatment of the preparation of embodiment 5.It is stated when further consultation: after taking three doses, stomach
Pain subtracts greatly, flatus (exhaust) is more, temperature, stool be not more under rushing down by sour regurgitation brothers, has felt brisk from head to foot, patient is because of soup of going on business
Medicine take it is inconvenient ground with original side's double quantity it is encapsulated, one time three, three times per day.(avoid and drink and satiate, eat cool object), half
Year after follow-up, report to more.
Test example 2
Liu, female, 32 years old, usually element love is angry, uncomfortable in chronognosis stomach, and like the object of food ice cream and cold drink, positive value summer
It is hot, be Xie Qire, eat have a stomachache after five ice creams, idols more very, sweat all over, vomit companion's coffee object, remove hospital emergency, give only
Pain and symptomatic treatment, symptom are alleviated, after make gastroscope and show: gastric erosion attends by routed soup, allows other oral western medicines to treat, patient is not
It is willing to the diagnosis and treatment of coming (because its household has larger peptic ulcer medical history, oral western medicine side effect and recurrent exerbation, is not easy to cure):
Hope its sallow complexion (because peptic ulcer has chronic bleeding and absorb nutrition it is poor caused by), deficiency of QI with disinclination to talk of speaking, positive value summer
It wears the clothes thicker (also do not think heat), the fat big heel teeth trace of pale tongue, the thin and delicate inability of six deeptensepulses.Be for feelings will on ordinary days it is unsmooth (Wood restricts earth)
In addition improper diet injure middle-jiao yang, function of the spleen and stomach, improve its transportation capabilities first, the biochemical weary source of qi and blood thus form this disease.Give embodiment 5
It gives for three doses of decoction and treats.When further consultation, thick clothes is no longer worn, can wear half sleeve, has been fitted in stomach, complexion is gradually good therefore is
Chronic disease needs the long period to recuperate under medical treatment, and then takes the pill of embodiment 2, three grams every time, three times per day take, two months with exhausted
Future trouble.Even after half a year on the way to encounter, become quite a different person, complexion is ruddy, it is sonorous and forceful to speak, and few anger is eaten cold less after reporting to
Drink, in order to avoid recurrence.
Embodiment 3
Zhang, female, 68 years old, because suffering from arthritis more than more than ten years, often oral analgesic and hormone drug maintain symptom, but nearly two
Year stomachache more very when sour regurgitation breastbone after burn feeling (caused by taking anodyne and hormone).Gastroscope shows: reflux esophagitis and stomach ten
Two Duodenalulcers, through diagnosis and treatment: its complexion nigrescence, arthrocele pain, hiccup, mouth being hoped to have fishy taste, tongue neatly side to have indentation
Pastiness purple, the left pass string thin portion Tiangeng of deeptensepulse.Be in entering for worn with age, YANG QI deficiency, cold-evil and oral western medicine injure middle soil therefore
Form this disease.Control with；It helps positive middle benefit gas, eliminating cold to stop pain, activate blood circulation and disperse blood clots, regulating qi-flowing for harmonizing stomach.The decoction treatment for giving embodiment 5, takes
Its sour regurgitation of having a stomachache is slightly good after upper five doses (being the lower sun great void in), then increases three doses of medicine medical treatments of dosage with original side；Three examine after its
Symptom is greatly improved and extremities joint pain is also alleviated (because of ten sick nine cold spleen governing limbs, the prosperous then extremities joint benefit of spleen), because
Patient it is with family in straitened circumstances it is special with top triplication levigation, every time 9 grams two times a day take after mixing it with water.One son Nian Houqi comes diagnosis and treatment stomach and intestine
Illness simultaneously reports to my father and has been cured (healthy enough to enjoy food and drinks and save pain might as well be more than half).
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of pharmaceutical composition for treating peptic ulcer, which is characterized in that the composition includes the following raw material: black attached
Son, gun ginger, radix glycyrrhizae preparata, ginseng, Rhizoma Atractylodis Macrocephalae, Cortex Magnoliae Officinalis, Radix Astragali, wrinkled giant hyssop, cuttle bone, excrementum pteropi, cornu cerve degelatinatum, fish glue, Radix Notoginseng, Zhejiang
Fritillaria, aspongopus, Rheum palmatum (processed with wine) and evodia rutaecarpa.
2. the pharmaceutical composition for the treatment of peptic ulcer according to claim 1, which is characterized in that according to parts by weight, institute
The composition stated includes the following raw material: Radix Aconiti Lateralis Preparata 60-90 parts by weight, gun ginger 25-45 parts by weight, radix glycyrrhizae preparata 20-30 parts by weight,
Ginseng 18-30 parts by weight, Rhizoma Atractylodis Macrocephalae 15-45 parts by weight, Cortex Magnoliae Officinalis 18-35 parts by weight, Radix Astragali 60-150 parts by weight, wrinkled giant hyssop 25-30 weight
Measure part, cuttle bone 15-30 parts by weight, excrementum pteropi 15-30 parts by weight, cornu cerve degelatinatum 18-30 parts by weight, fish glue 15-30 parts by weight,
Radix Notoginseng 8-20 parts by weight, fritillaria thunbergii 15-30 parts by weight, aspongopus 18-30 parts by weight, Rheum palmatum (processed with wine) 15-25 parts by weight and evodia rutaecarpa
15-45 parts by weight.
3. the pharmaceutical composition for the treatment of peptic ulcer according to claim 1 or 2, which is characterized in that according to parts by weight,
The composition includes the following raw material: Radix Aconiti Lateralis Preparata 70-80 parts by weight, gun ginger 30-40 parts by weight, radix glycyrrhizae preparata 23-27 weight
Part, ginseng 22-26 parts by weight, Rhizoma Atractylodis Macrocephalae 25-35 parts by weight, Cortex Magnoliae Officinalis 24-29 parts by weight, Radix Astragali 100-110 parts by weight, wrinkled giant hyssop 27-
28 parts by weight, cuttle bone 20-25 parts by weight, excrementum pteropi 20-25 parts by weight, cornu cerve degelatinatum 22-26 parts by weight, fish glue 20-25 weight
Measure part, Radix Notoginseng 12-16 parts by weight, fritillaria thunbergii 20-25 parts by weight, aspongopus 22-26 parts by weight, Rheum palmatum (processed with wine) 18-22 parts by weight and
Evodia rutaecarpa 28-32 parts by weight.
4. the pharmaceutical composition for the treatment of peptic ulcer according to claim 1 or 2, which is characterized in that according to parts by weight,
The composition includes the following raw material: 75 parts by weight of Radix Aconiti Lateralis Preparata, 35 parts by weight of gun ginger, 25 parts by weight of radix glycyrrhizae preparata, ginseng 24
Parts by weight, 30 parts by weight of Rhizoma Atractylodis Macrocephalae, 26.5 parts by weight of Cortex Magnoliae Officinalis, 105 parts by weight of Radix Astragali, 27.5 parts by weight of wrinkled giant hyssop, 22.5 weight of cuttle bone
Measure part, 22.5 parts by weight of excrementum pteropi, 24 parts by weight of cornu cerve degelatinatum, 22.5 parts by weight of fish glue, 14 parts by weight of Radix Notoginseng, fritillaria thunbergii 22.5
Parts by weight, 30 parts by weight of 24 parts by weight of aspongopus, 20 parts by weight of Rheum palmatum (processed with wine) and evodia rutaecarpa.
5. the pharmaceutical composition for the treatment of peptic ulcer according to any one of claims 1-4, which is characterized in that described
Pharmaceutical composition also include pharmaceutically acceptable auxiliary material or carrier, preferably pill, capsule or decoction.
6. a kind of preparation method of the pharmaceutical composition for the treatment of peptic ulcer described in claim 1-5 any one, special
Sign is that the method includes the following steps:
(1) each raw material is weighed according to formula rate, is ground into fine powder respectively, then carry out uniformly mixed, obtain traditional Chinese medicine powder；
(2) medically acceptable auxiliary material or carrier is added in the traditional Chinese medicine powder and pharmaceutical dosage form is made.
7. the preparation method of the pharmaceutical composition for the treatment of peptic ulcer according to claim 6, which is characterized in that described
Pharmaceutical composition be pill, auxiliary material be fecula and water.
8. the preparation method of the pharmaceutical composition for the treatment of peptic ulcer according to claim 7, which is characterized in that described
The diameter of pill is 3-5mm.
9. the preparation method of the pharmaceutical composition for the treatment of peptic ulcer according to claim 7 or 8, which is characterized in that
The mass ratio of traditional Chinese medicine powder, fecula and water is 9-11:1-3:4-6, preferably 10:2:5.
10. the preparation method of the pharmaceutical composition for the treatment of peptic ulcer according to claim 6, which is characterized in that institute
The pharmaceutical composition stated is capsule, every 0.75g containing traditional Chinese medicine powder.
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| CN101279041A (en) * | 2008-05-15 | 2008-10-08 | 陈子义 | Chinese medicinal composition for curing ulcer of upper digestive tract |
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| CN101279041A (en) * | 2008-05-15 | 2008-10-08 | 陈子义 | Chinese medicinal composition for curing ulcer of upper digestive tract |
| CN102671098A (en) * | 2012-05-15 | 2012-09-19 | 宋协勘 | Traditional Chinese medicine for treating peptic ulcer |
| CN104758878A (en) * | 2015-03-18 | 2015-07-08 | 覃慧璇 | Traditional Chinese medicine composition for treating gastroduodenal ulcer in the type of cold evil invading stomach |
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