CN109700488A - A kind of external fine grained fat prepares all-in-one machine - Google Patents

A kind of external fine grained fat prepares all-in-one machine Download PDF

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Publication number
CN109700488A
CN109700488A CN201910125174.3A CN201910125174A CN109700488A CN 109700488 A CN109700488 A CN 109700488A CN 201910125174 A CN201910125174 A CN 201910125174A CN 109700488 A CN109700488 A CN 109700488A
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cavity
fat
machine
fine grained
prepares
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CN109700488B (en
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范鹏举
李珍
谭鹜远
方曼
王永杰
刘晓谨
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Changsha Fuyan Medical Technology Co ltd
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Xiangya Hospital of Central South University
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Abstract

A kind of external fine grained fat prepares all-in-one machine, the cavity including a sterile sealing, and the cavity is equipped with inlet and outlet, the import of the cavity and heavy caliber liposuction pipe (caliber >=4mm, side opening area >=10mm2) connect, the outlet of the cavity is connect by silicone tube with high negative pressure device, and lipochondrion cutter device and wash mill are provided in the cavity.The problems such as suction lipectomy is time-consuming and laborious during the present invention solves fat transfer, and fat stem cell content is low, purification process is easy to pollute.

Description

A kind of external fine grained fat prepares all-in-one machine
Technical field
The present invention relates to a kind of external fine grained fat to prepare all-in-one machine.
Background technique
Autologous fat is because of abundance, and materials are convenient, and no rejection is easy to operate, and filling shape is good, and there is no diseases to pass Dye, it is postoperative not leave the multiple advantages such as scar, it is widely used in clinic, is even more to become tissue filling in plastic surgery, the surface of a wound is repaired Multiple conventional means.But its transplanting survival rate, the uncertainty of especially long-term surviving are still the main barrier for limiting its application so far Hinder.Survival rate especially long-term surviving rate fatty after transplanting is improved, is still that current needs urgently solve the problems, such as.Numerous studies are aobvious Show: transplant fat tissue volume still can only retain 50%-80 at present.
Researches show that: transplanting early stage, adipose tissue are in ischemic, anaerobic condition, provide nutrition, rouge by surrounding tissue liquid Fat cell is away from by existence in area 1.5 ± 0.5mm of interstitial fluid, well, 5 days after operation new vessels are sprouted by graft periphery Hair, but such as lipochondrion diameter is more than 2mm, is limited by tissue fluid disperse distance, and lipochondrion center fat cell is sought because obtaining It supports and oxygen is limited and liquefaction, necrosis occurs.So the fat of transplanting is being obtained nutrition early stage by area, is establishing blood supply in time and exist It is largely determined by lipochondrion diameter.
2001, Zuk etc. had found mescenchymal stem cell (mesenchymal stem in adipose tissue for the first time Cells, MSCs), referred to as adipose-derived stem cells (adipose-derived stem cells, ADSCs).With derived from bone marrow MSCs is the same, and ADSCs equally has good self-renewing and multi-lineage potential.But fat stem cell, which obtains, to be more convenient, and Pain is smaller, it is often more important that stem cell content is 500~1000 times of marrow in adipose tissue.ADSCs is in fat transfer On the one hand the vessel density in free grafting adipose tissue can be improved in journey, help graft early stage to establish in time and sufficient Blood supply;On the other hand it can be divided into fat cell, reduced adipocyte number is supplemented, to effectively raise transplanting rouge The survival rate of fat.Improve the content of ADSCs in transplant fat.
Large Diameter Pipeline (refers to φ >=4mm, side opening aperture area S >=10mm2Caliber) liposuction needle obtain lipochondrion Greatly, and the disperse of tissue fluid apart from limited, fatty centrocyte transports bad necrosis because of blood.Therefore, clinical generally acknowledged small diameter tube (φ= 2mm, S=1mm2), lower negative pressure suction lipectomy be that fat transfer is successfully crucial, Large Diameter Pipeline liposuction pipe do not recommend for fat move Plant liposuction.
Although small diameter tube liposuction pipe liposuction has many advantages, ADSCs content is lower in the Grainy fat tissue aspirated, Analysis reason may be mainly distributed on ADSCs it is related around the interstitial blood vessel and fascia connective tissue of adipose tissue, due to blood The relatively fine and close and larger toughness feature of the tissue of pipe and fascia connective tissue, causes in fat acquired in small-bore liposuction pipe ADSCs content is substantially reduced compared with donor site ADSCs content.
Summary of the invention
The present invention solves the deficiencies in the prior art and provides that a kind of liposuction is high-efficient, fatty survival rate is high after transplanting External fine grained fat prepares all-in-one machine, and fine grained fat here refers to the Grainy fat tissue of particle diameter d < 2mm.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of external fine grained fat prepares all-in-one machine, the cavity including a sterile sealing, and the cavity is equipped with import And outlet, the import of the cavity are connect with heavy caliber liposuction pipe, the outlet of the cavity passes through silicone tube and high negative pressure device It connects, is provided with lipochondrion cutter device and wash mill in the cavity.The present apparatus using hospital's vacuum suction system or Conventional fatty negative suction system (negative pressure value of high negative pressure device here is in 0.02~0.07Mpa), by vacuum suction system It unites and is connected with the silicone tube for the outlet for connecting the cavity, so that cavity is interior and cavity outlet forms high negative pressure, passed through Heavy caliber liposuction pipe aspirates patient's fat, and the bulky grain fat after suction passes through the cutting and grinding of lipochondrion cutter device For little particle fat, not only solve the problems, such as because lipochondrion it is excessive caused by fat cell necrosis, and and solve institute The problem that ADSCs content is too low in adipose tissue is obtained, while also ensuring cell activity, experiment is it has also been found that use Large Diameter Pipeline liposuction Pipe, is remarkably improved clinical liposuction efficiency.
Further, the lipochondrion cutter device includes that setting is accepting the hopper outlet of lipochondrion just in the cavity The set of blades of lower section and the first motor for driving the set of blades rotation.
Further, the multiple groups that the set of blades is axially laid along rotary shaft, every group of set of blades includes along axisymmetry At least two panels blade laid, the blade and horizontal plane are equipped with 0 °~15 ° of angle, that is, say that blade can be with horizontal plane In parallel.
Further, it is additionally provided on the cavity to the wash mill of chamber body fat water flowing cleaning and for fat discharge Fat discharge collection port, the intracorporal washing water of chamber is discharged by the high negative pressure device of cavity outlet.
Further, the wash mill includes water inlet and catch tray, the outlet of the lipochondrion cutter device with The connection of catch tray upper opening, the surrounding of the catch tray and bottom surface are strainer, upper opening, the opening of sieve of the catch tray Diameter is less than the lipochondrion after cutting, and the bottom of the catch tray is equipped with valve and is connected to by pipeline with fat discharge collection port, The outside of catch tray is arranged in the outlet of the cavity.Spray head is equipped in the cavity on water inlet, the spray head is towards rouge Fat particle cutter device.
Further, the bottom of the catch tray is back taper.
Further, agitating device is equipped in the lower section of catch tray in the cavity.
Further, the agitating device includes the of setting stirring blade in the cavity and driving stirring blade rotation Two motors.
Further, the bottom of the cavity is equipped with sewage draining exit.
Further, including cylinder, the cylinder middle part form the cavity, successively include from top to bottom in the cavity Cutting region, collecting zone and stirring region, the lipochondrion cutter device setting is in cutting region, the catch tray setting In collecting zone, the blender is arranged in stirring region.
Further, the blade is connect by rotary shaft with the first motor output end being arranged outside cylinder, the rotation Axis and cavity inner wall are sealed using seal assembly, and the agitating shaft of the agitating device also uses seal assembly close with cavity inner wall Envelope.
Using above-mentioned apparatus, change that " small diameter tube, lower negative pressure liposuction pipe must be used when fat transfer liposuction " is intrinsic to face Bed thinking, by carefully analyze and preliminary experiment verify, production invent external fine grained fat pulverizer on the basis of, solve The obstacle that current fat transfer is faced starts a completely new, a whole set of fat transfer technology.Pass through comparative analysis osculum Diameter liposuction pipe, in high negative pressure, aspirates equal volume Grainy fat tissue ADSCs content in lower negative pressure and heavy caliber liposuction pipe, digested, After cultivating and counting, stem cell population contained by the latter is found as the former 1.7~3 times, therefore heavy caliber, high negative pressure suction tube are more Be conducive to ADSCs acquisition, the present apparatus makes bulky grain rouge using the fatty cutting and grinding in vitro being aspirated heavy caliber liposuction pipe Fat becomes little particle fat, not only solve the problems, such as because lipochondrion it is excessive caused by fat cell necrosis, and solve institute The problem that ADSCs content is too low in adipose tissue is obtained, while also ensuring cell activity, experiment is it has also been found that use Large Diameter Pipeline liposuction Pipe, is remarkably improved clinical liposuction efficiency (up to 3~5 times).
In conclusion suction lipectomy is time-consuming and laborious during the present invention solves fat transfer, fat stem cell content is low, The problems such as purification process is easy to pollute.
Detailed description of the invention
Fig. 1 is the structural diagram of the present invention.
Fig. 2 is a kind of main view of embodiment of set of blades of the present invention.
Fig. 3 is the left view of Fig. 2.
Fig. 4 is the top view of Fig. 2.
Fig. 5 is the main view of the another embodiment of set of blades of the present invention.
Fig. 6 is the top view of Fig. 5.
In attached drawing, 1, cylinder, 11, grease absorbing port, 12, water inlet;13, drainage by suction mouth, 14, fat discharge collection port, 15, Sewage draining exit, 21, first motor, 22, first motor fixed frame, the 23, first rotary shaft, 24, blade, 25, knife rest, 26, first is close Sealing, the 27, first transmission device, the 31, second motor, the 32, second transmission device, 33, second seal, 34, stirring blade, 4, Catch tray, 5, protective net, 6, stabilizer blade, 7, hose road.
Specific embodiment
For a better understanding of the present invention, with reference to the accompanying drawing and embodiment, invention is described in further detail, but Embodiments of the present invention are not limited only to this, and protection scope of the present invention is also related to those skilled in the art and conceives according to the present invention It is conceivable that equivalent technologies mean.
Embodiment 1:
As shown in Figure 1, core of the present embodiment as the present apparatus, including cylinder 1, the cylinder 1 are supported on by stabilizer blade 6 On ground, cavity is formed in the middle part of the cylinder 1, the cylinder 1 is equipped with grease absorbing port 11, water inlet 12, drainage by suction mouth 13, fat Discharge collection port 14 and sewage draining exit 15, the import of the grease absorbing port 11 connect the (φ of heavy caliber liposuction pipe with heavy caliber liposuction pipe >=4mm, side opening aperture area S >=10mm2), the drainage by suction mouth 13 connect that (high negative pressure here is with high negative pressure suction tube Negative pressure value is in 0.02~0.07Mpa), lipochondrion cutter device is provided in the cylinder 1.
The lipochondrion cutter device includes being arranged in cylinder 1 described in the set of blades and drive of 11 underface of grease absorbing port The first motor 21 of set of blades rotation, the first motor 21 are fixed on cylinder 1 by first motor fixed frame 22, and described the One motor 21 is connect by the first transmission device 27 with the first rotary shaft 23, and the set of blades is mounted in the first rotary shaft 23, First rotary shaft 23 is tightly connected by first seal 26 and cylinder.
In the present embodiment, the lower section of grease absorbing port 11 is equipped with first funnel 111, and the outlet of the first funnel 111 is directed at knife Piece group guarantees to enter back into after the cutting that the fat that grease absorbing port 11 is come in passes through set of blades to next step.
As shown in Fig. 2 to 5, there are many set of blades is arranged form,
The first: set of blades include one layer, every group of set of blades include the two panels blade 24 being symmetrically mounted on knife rest 25 or The angle a of four blades 24, the blade 24 and horizontal plane is 0 °.
Second: set of blades sets two groups up and down, and every group of set of blades includes the two panels blade 24 being symmetrically mounted on knife rest 25 Or four blades 24, the angle a of the blade and horizontal plane are 15 °.
It, can be more preferable by the way that bulky grain fat can be cut into thinner lipochondrion under the double-deck even multi-layer cutter blade Undertaking fat.
In this example
Embodiment 2:
The present embodiment is further improved on the basis of embodiment 1, is equipped with spray head, the spray in cylinder 1 on water inlet Head are connected to set of blades, the outlet of the lipochondrion cutter device with 4 upper opening of catch tray, and the four of the catch tray 4 Week and bottom surface are strainer, upper opening, and the aperture of filter screen of the catch tray 4 is less than the lipochondrion after cutting, the collection The bottom of disk 4 is equipped with valve and is connected to by hose road 7 with fat discharge collection port, and the drainage by suction mouth 13 of the cylinder 1 is arranged In the exterior lateral sides of catch tray 4, not higher than the upper opening of catch tray 4.It, can be in cutting bulky grain fat using the present embodiment While realize the cleaning of lipochondrion, watery blood after cleaning from the outlet of cavity by negative pressure extraction, and little particle fat by In the filtration of strainer, to stay in catch tray, collection port, which is discharged, by fat can be clamped syringe, by little particle rouge Fat extraction.
In this example, the bottom of the catch tray 4 is back taper, facilitates the collection of lipochondrion.
Embodiment 3:
The present embodiment is further improved on the basis of embodiment 2, is equipped with stirring dress in the lower section of catch tray 4 in cylinder 1 It sets, is separated between catch tray 4 and agitating device by protective net 5, the agitating device includes the paddle of setting in the cavity Second motor 31 of piece 34 and driving stirring blade rotation, second motor 31 pass through the second transmission device 32 and the second rotation Axis connection, the stirring blade 34 are mounted on the second shaft axis, and the second shaft axis and cylinder 1 pass through second seal 33 It is tightly connected, from top to bottom successively includes cutting region, collecting zone and stirring region in the cavity, the lipochondrion is cut Device setting is cut in cutting region, in collecting zone, the agitating device is arranged in stirring region, in this way for the catch tray setting Agitating device stirs the lipochondrion of cutting and crushing, so that sewage is further discharged, guarantees the cleaning effect of lipochondrion, and And the sewage draining exit of the bottom by the cavity, cavity can also be cleaned.
In use, vacuum suction system is connected to the cavity by silicone tube and is entered using hospital's vacuum suction system Mouthful, so that cavity is interior and cavity outlet forms high negative pressure, patient's fat is aspirated by heavy caliber liposuction pipe.
In addition, it should be noted that, this patent is not limited to above embodiment, as long as its part does not specify specific size Or shape, then the part can be any size or shape adaptable with its structure, no matter and making in its material composition Any variation, it is all to be designed using structure provided by the present invention, all it is a kind of deformation of the invention, is considered as in the present invention Within protection scope.

Claims (12)

1. a kind of external fine grained fat prepares all-in-one machine, it is characterised in that: the cavity including a sterile sealing, the cavity Equipped with inlet and outlet, the import of the cavity is connect with heavy caliber liposuction pipe, and the outlet of the cavity and high negative pressure device connect It connects, lipochondrion cutter device is provided in the cavity.
2. external fine grained fat according to claim 1 prepares all-in-one machine, it is characterised in that: the lipochondrion cutting Device include setting accept in the cavity the first funnel of lipochondrion, the set of blades that is arranged in immediately below the first hopper outlet and Drive the first motor of the set of blades rotation.
3. external fine grained fat according to claim 2 prepares all-in-one machine, it is characterised in that: the set of blades is along rotation The multiple groups that axis is axially laid, every group of set of blades include at least two panels blade laid along axisymmetry, the blade and level Face is equipped with 0 °~15 ° of angle.
4. preparing all-in-one machine to external fine grained fat described in one of 3 according to claim 1, it is characterised in that: the cavity On be additionally provided with to chamber body fat water flowing cleaning wash mill and for fat discharge fat discharge collection port, the cavity Interior washing water is discharged by the high negative pressure device of cavity outlet.
5. external fine grained fat according to claim 4 prepares all-in-one machine, it is characterised in that: the wash mill includes The outlet of water inlet and catch tray, the lipochondrion cutter device is connected to catch tray upper opening, and the four of the catch tray Week and bottom surface are strainer, upper opening, and the aperture of filter screen of the catch tray is less than the lipochondrion after cutting, the catch tray Bottom be equipped with valve by pipeline with fat be discharged collection port be connected to, the outside of catch tray is arranged in the outlet of the cavity.
6. external fine grained fat according to claim 5 prepares all-in-one machine, it is characterised in that: intaking in the cavity Mouth is equipped with spray head, and the spray head is towards lipochondrion cutter device.
7. external fine grained fat according to claim 5 prepares all-in-one machine, it is characterised in that: the bottom of the catch tray For back taper.
8. external fine grained fat according to claim 5 prepares all-in-one machine, it is characterised in that: collected in the cavity The lower section of disk is equipped with agitating device.
9. external fine grained fat according to claim 8 prepares all-in-one machine, it is characterised in that: the agitating device includes Stirring blade in the cavity and the second motor of driving stirring blade rotation are set.
10. external fine grained fat according to claim 5 prepares all-in-one machine, it is characterised in that: the bottom of the cavity Equipped with sewage draining valve.
11. external fine grained fat according to claim 8 prepares all-in-one machine, it is characterised in that: it further include cylinder, it is described The cavity is formed in the middle part of cylinder, from top to bottom successively includes cutting region, collecting zone and stirring region, institute in the cavity The setting of lipochondrion cutter device is stated in cutting region, the catch tray setting exists in collecting zone, the agitating device setting Stirring region.
12. external fine grained fat according to claim 11 prepares all-in-one machine, it is characterised in that: the blade passes through rotation Shaft is connect with the first motor output end outside setting cylinder, and the rotary shaft and cavity inner wall are sealed using seal assembly, institute The agitating shaft for stating agitating device also uses seal assembly to seal with cavity inner wall.
CN201910125174.3A 2019-02-20 2019-02-20 External fine particle fat preparation all-in-one Active CN109700488B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110523491A (en) * 2019-09-30 2019-12-03 中南大学湘雅医院 A kind of Fat cutter
CN110560232A (en) * 2019-09-30 2019-12-13 中南大学湘雅医院 External fine particle fat preparation all-in-one
CN110743447A (en) * 2019-10-15 2020-02-04 北京润美玉之光医疗美容门诊部 Method for improving autologous fat transplantation survival rate
WO2021062967A1 (en) * 2019-09-30 2021-04-08 中南大学湘雅医院 Adipose cutter and all-in-one machine for in-vitro fine granular adipose preparation

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CN207452106U (en) * 2017-06-27 2018-06-05 谭铖洸 For the fat-derived primary stem cell collection piece-rate system of binary channels of human body liposuction
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KR20090000768U (en) * 2008-12-18 2009-01-28 배동환 Hand piece for liposuction device
US20180221550A1 (en) * 2011-07-08 2018-08-09 Jointechlabs, Inc. System and methods for preparation of adipose-derived stem cells
US20170049942A1 (en) * 2015-08-20 2017-02-23 Purecraft LLC Liposuction device and system and use thereof
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110523491A (en) * 2019-09-30 2019-12-03 中南大学湘雅医院 A kind of Fat cutter
CN110560232A (en) * 2019-09-30 2019-12-13 中南大学湘雅医院 External fine particle fat preparation all-in-one
WO2021062967A1 (en) * 2019-09-30 2021-04-08 中南大学湘雅医院 Adipose cutter and all-in-one machine for in-vitro fine granular adipose preparation
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CN110560232B (en) * 2019-09-30 2024-04-30 长沙赋妍医疗科技有限公司 External fine particle fat preparation all-in-one
CN110743447A (en) * 2019-10-15 2020-02-04 北京润美玉之光医疗美容门诊部 Method for improving autologous fat transplantation survival rate
CN110743447B (en) * 2019-10-15 2021-10-08 北京润美玉之光医疗美容门诊部 Method for improving autologous fat transplantation survival rate

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