WO2021062967A1

WO2021062967A1 - Adipose cutter and all-in-one machine for in-vitro fine granular adipose preparation

Info

Publication number: WO2021062967A1
Application number: PCT/CN2020/072819
Authority: WO
Inventors: 范鹏举; 李珍; 方曼; 李晶晶
Original assignee: 中南大学湘雅医院
Priority date: 2019-09-30
Filing date: 2020-01-17
Publication date: 2021-04-08

Abstract

Disclosed are an adipose cutter and an all-in-one machine for in-vitro fine granular adipose preparation. The adipose cutter comprises an adipose intake channel (12), an adipose output channel (22), at least one group of blades (31) arranged between an outlet of the adipose intake channel (12) and an inlet of the adipose output channel (22), and a housing for sealing a space where the outlet of the adipose intake channel (12), the inlet of the adipose output channel (22) and the blades (31) are located, wherein an adipose inlet (11) of the adipose intake channel (12) is connected to an adipose suction pipe (14); an adipose outlet (21) of the adipose output channel (22) is connected to a high-negative-pressure device; and the outlet of the adipose intake channel (12) is arranged opposite the inlet of the adipose output channel (22), and the interval therebetween matches the thickness of the blades. In a working state, cutting edges of the blades (31) penetrate a connecting line between the outlet of the adipose intake channel and the inlet of the adipose output channel so as to cut adipose granules. The all-in-one machine for in-vitro fine granular adipose preparation comprises the adipose cutter, a negative pressure generator (94), and an adipose collection tank (6). It is guaranteed that the diameter of adipose granules obtained by cutting is less than or equal to 2 mm, such that the necrosis of the center of transplanted adipose caused by overlarge granules is effectively avoided.

Description

Fat cutter and integrated machine for preparing extracorporeal fine particle fat

Technical field

The invention relates to a fat cutter and an integrated machine for preparing extracorporeal fine particle fat.

Background technique

Autologous fat has many advantages, such as abundant sources, convenient materials, no rejection, simple operation, good filling appearance, no disease transmission, no scars left after surgery, etc., has been widely used in clinical practice, and it has become tissue filling in plastic surgery. Common methods of wound repair. However, its transplant survival rate, especially the uncertainty of long-term survival, is still the main obstacle that limits its application. Improving the survival rate of fat after transplantation, especially the long-term survival rate, is still a problem that needs to be solved urgently. A large number of studies have shown that: at present, the volume of transplanted fat tissue can still only retain 50%-80%.

Studies have shown that in the early stage of transplantation, the adipose tissue is in a state of ischemia and hypoxia, and it depends on the surrounding tissue fluid to provide nutrition. The fat cells survive well within 1.5±0.5mm from the interstitial fluid of the recipient area, and the neovascularization starts from the periphery of the graft 5 days after the operation. Germination, but if the diameter of the fat particles exceeds 2mm, the fat cells in the center of the fat particles are liquefied and necrotic due to limited access to nutrients and oxygen due to the limitation of the distance of interstitial fluid dispersion. Therefore, the early nutrition of the transplanted fat and the timely establishment of blood supply in the recipient area are largely determined by the diameter of the fat particles.

In 2001, Zuk et al. discovered mesenchymal stem cells (MSCs) in adipose tissue for the first time, called adipose-derived stem cells (ADSCs). Like bone marrow-derived MSCs, ADSCs also have good self-renewal and multi-directional differentiation potential. However, adipose stem cells are more convenient to obtain and less painful. More importantly, the content of stem cells in adipose tissue is 500 to 1000 times that of bone marrow. In the process of fat transplantation, ADSCs can increase the density of blood vessels in the free transplanted fat tissue on the one hand, and help the graft establish a timely and adequate blood supply in the early stage; on the other hand, it can differentiate into fat cells to supplement the reduced number of fat cells, thereby effectively Improve the survival rate of transplanted fat. Increase the content of ADSCs in transplanted fat.

Large pipe diameter (here refers to

Side hole diameter area S≥10mm2) The fat particles obtained by the liposuction needle are large, but the diffusion distance of the tissue fluid is limited, and the fat center cells are necrotic due to poor blood supply. Therefore, the clinically recognized small tube diameter (

S=1mm2). Low negative pressure liposuction is the key to the success of fat transplantation. Large-diameter liposuction tubes are not recommended for liposuction for fat transplantation. Although the small-diameter liposuction tube has many advantages for liposuction, the content of ADSCs in the fat particles sucked is low. The analysis reason may be related to the distribution of ADSCs mainly around the interstitial blood vessels and fascial connective tissues of adipose tissue. The tissues of blood vessels and fascia connective tissues are relatively dense and tough, resulting in a significant decrease in the content of ADSCs in the fat obtained by the small-caliber liposuction tube compared with the ADSCs content of the donor site and lack of extracellular matrix (including fascial connective tissue, intercellular matrix). Blood vessels, etc.), even if the extracellular matrix is obtained, due to its characteristics, it is easy to form a network mass, which makes it relatively large and difficult to inject.

The current application number is: 201910125174.3, and the patent name is an in vitro fine particle fat preparation integrated machine. It discloses a device that uses a large-caliber liposuction tube to suck fat and then cuts the fat through a cutting device. This device has high liposuction efficiency and is transplanted. The survival rate of the rear fat is high, which can solve the above technical problems. However, further research on this device has found that the cutting effect of the cutting part is unstable. The fat particles after cutting are large or small. The fat after cutting is easy to splash and cause fat loss. The collection part is inconvenient to disassemble, maintain and disinfect, and may cause fat bacterial contamination.

technical problem

The solution to the problem

Technical solutions

A fat cutter includes a fat inlet channel 12, a fat outlet channel 22, at least one set of blades 31 arranged between the outlet of the fat inlet channel 12 and the inlet of the fat outlet channel 22, and the outlet of the fat inlet channel 12 and the fat outlet channel The inlet of 22 and the space where the blade 31 is located are sealed, the grease inlet 11 of the grease inlet 12 is connected to the large-caliber liposuction tube 14, and the grease outlet 21 of the grease outlet 22 is connected to a high negative pressure device connection,

The outlet of the grease inlet channel 12 and the inlet of the grease outlet channel 22 are arranged oppositely to form cutting grooves with an interval matching the thickness of the blade. The outlet of the grease inlet channel 12 is arranged above the inlet of the grease outlet channel 22. The cutting edge of the blade 31 passes through the connecting line between the outlet of the fat inlet channel 12 and the inlet of the fat outlet channel 22 to cut fat particles. With the above structure, under the traction of negative pressure, fat enters the fat inlet channel 12 through the large-caliber liposuction tube, and then the fat flows out from the outlet of the fat inlet channel 12 and is about to fall into the inlet of the fat outlet channel 22 through the high-speed The rotating blade cuts the fat into smaller particles. The cut small particles of fat are sucked out of the device under negative pressure traction. Because the gap between the fat inlet channel 12 and the fat outlet channel 22 is small, and the negative pressure in the pipeline is less than or equal to The negative pressure in the cutting cavity, on the one hand, the fat particles lack the force to leave the pipeline, so that the cut fat particles are directly drawn into the fat outlet channel by the negative pressure, which minimizes the residual fat particles inside the device. On the other hand, It can ensure that the cut fat particles are not cut multiple times, reducing the damage to the fat particles; by controlling the speed of the blade, the diameter of the cut fat particles can be adjusted appropriately to meet different needs. This device can be used for For fat transplantation and simple liposuction, the device is directly connected to the negative pressure tank in the case of simple fat suction, and when it is used for fat transplantation, the negative pressure generator is connected to the fat collection tank and then connected to the device, so that the device There can be multiple applications.

In the above embodiment, the housing includes a cutting table 2 and an upper end cover 1 installed above the cutting table 2. A fat particle cutting device 3 that drives a blade set is installed in the cutting table 2 and the upper end cover 1 is provided with There is a grease inlet channel 12, the cutting table 2 is provided with a grease outlet channel 22 at a position corresponding to the grease inlet channel 12, and the upper end cover 1 is sealed and installed on the cutting table 2 by a seal. In the assembled state, the Between the upper end cover 1 and the cutting table 2, in the area where the outlet of the grease inlet channel 12 and the inlet of the grease outlet channel 22 are located, there are spaced annular cutting grooves, and the blade group of the fat particle cutting device 3 is arranged in the cutting grooves. The upper end cover 1 is used to seal the cutting table 2 to form a cutting groove, which facilitates the disassembly and maintenance of the overall structure. When all parts of the device are made of food-grade stainless steel or polymer materials, it is convenient for high temperature and high pressure sterilization of the device.

In the above embodiment, the outlet of the grease inlet channel 12 is coaxially arranged above the inlet of the grease outlet channel 22, and the projection of the outlet of the grease inlet channel 12 on the horizontal plane is within the projection range of the inlet of the grease outlet channel 22 on the horizontal plane. The axes of the grease inlet channel 12 and the grease outlet channel 22 are arranged in parallel with the axis of rotation of the blade 31. In this way, under the action of negative pressure, the fat falling from the fat inlet channel 12 can accurately fall into the fat outlet channel to prevent fat loss.

In the above embodiment, the cutting edge and the cutting surface of the blade 31 are perpendicular to the axes of the grease inlet channel 12 and the grease outlet channel 22. This ensures the cutting effect and prevents sputtering during cutting.

In the above embodiment, the height of the cutting groove is 2 to 4 mm. This height matches the thickness of the blade, on the one hand to ensure the effect of negative pressure, on the other hand to prevent the blade from interfering with the cutting groove wall when rotating.

In the above embodiment, the inner side of the upper end cover 1 is sealed to the outer side of the cutting table 2 through the O-ring 4.

In the above embodiment, the grease inlet 11 of the grease inlet channel 12 and the grease outlet 21 of the grease outlet channel 22 are provided with a quick connection joint 93. This facilitates the quick connection and disassembly of the pipeline and the device.

In the above embodiment, the fat particle cutting device 3 includes a blade 31, a blade holder 32, a shaft, and a speed-regulating motor 38. The blade 31 is mounted on the blade holder 32, and the blade 31 and the blade holder are connected by a self-locking nut 33. 32 is fixed on the shaft, the shaft is mounted on the cutting table 2 through a bearing 35, the bearing 35 and the cutting table 2, the shaft and the cutting table 2 are sealed by a sealing ring 36, and the shaft is passed through a buffer coupling 37 Connect with the speed regulating motor 38.

In the above embodiment, the speed control motor 38 is electrically connected to the controller 5, and the controller 5 includes a speed display screen 51 for displaying the speed of the speed control motor 38, a speed control switch 52 for adjusting the speed of the speed control motor 38, and a display The work indicator light 53 of the speed motor 38 status and the power switch 54 that controls and adjusts the opening and closing of the motor.

In the above embodiment, the blade 31 can be adjusted within 0-4000 rpm, and the preferred rotation speed is 2500-3000 rpm. Through a large number of experiments, it is ensured that most of the fat particles obtained by cutting the blade at this speed are less than or equal to 2mm in diameter, which can effectively avoid the necrosis of the transplanted fat center caused by the excessively large particles.

In the above embodiment, the liposuction tube 14 has a length of 25-40 cm and a tube diameter of 4-5 mm. The liposuction end of the liposuction tube 14 is provided with 4-6 side holes, and the caliber area of each side hole is 20～30mm ² . The liposuction tube adopts this specification to ensure the requirements of large diameter and high negative pressure.

In the above embodiment, the liposuction tube 14 includes a handle 141 and a liposuction needle 142. The handle 141 is provided with a liposuction channel 1412 and a deflation channel 1411, and the housing is also provided with an air guide channel 18, The air guide channel 18 is in communication with the cutting groove 15, the outlet of the liposuction channel 1412 is connected to the grease inlet 11 of the grease channel 12 of the housing through the liposuction pipe 13, and the handle 141 is also provided with a connecting channel 1413, so A vent hole 1414 is provided on the outside of the handle 141. The front end of the vent channel 1411 is in communication with the connecting channel 1413. One end of the connecting channel 1413 is in communication with the vent hole 1414 provided on the handle 141, and the other end is connected to the liposuction channel. 1412 is connected, and the connecting passage 1413 and the liposuction passage 1412 are provided with an angle preventing the sucked fat from entering the connecting passage 1413 from the liposuction passage 1412. The outlet end of the deflation passage 1411 is connected to the housing through the deflation tube 19 The air inlet of the air guide channel 18 is connected. A deflation channel 1411 is added to the liposuction handle 141. The operator presses the deflation opening with fingers to open and close the deflation opening and adjust the opening size of the abandonment opening. When the deflation opening of the deflation channel 1411 is opened, the cutting groove 15 passes through the release opening. The air channel 1411 communicates with the outside, so that the negative pressure in the cutting groove 15 is reduced, and the force of sucking the fat is reduced, thus reducing the fat ejection phenomenon and reducing the fat damage.

In the above embodiment, the angle between the connecting channel 1413 and the liposuction channel 1412 facing the connecting head of the liposuction needle 142 is an acute angle. Prevent the sucked fat from entering the connecting channel 1413 from the liposuction channel 1412.

In the above embodiment, the handle 141 is provided with a groove 1415 in the area where the air release hole 1414 is located to facilitate the pressing and sealing of the thumb of the thumb. Thus, through the contact between the pad of the finger and the groove, it is convenient to seal and adjust the size of the vent hole.

In the above embodiment, the inner wall of the cutting groove 15 and the inner wall of the inlet of the fat outlet channel 22 are covered with a soft material layer to reduce the damage caused by fat hitting the inner wall.

In the above embodiment, the inlet of the grease channel 22 is smaller than the outlet of the cutting groove 15 to form a step 16, the inner wall of the step 16, the connection point of the step 16 and the outlet of the cutting groove 15, and the connection point of the step 16 and the inlet of the grease channel 22 They are all arc-shaped surfaces, so that the cut fat just falls into the arc-shaped surface due to the inertial running trajectory, and is quickly drawn away, avoiding the impact and rebound of two or more cuts.

The embodiment of the present invention also includes an in vitro fine particle fat preparation integrated machine, including the above-mentioned fat cutter, and also includes a fat collection tank 6, a negative pressure generator 94, and a negative pressure tank group. The fat collection tank 6 includes a cylinder. Body 62 and a filter cartridge 63. The top of the cylinder body 62 is open, and the bottom is provided with a negative pressure interface 69 to communicate with the inner cavity of the cylinder body 62. The filter cartridge 63 is composed of a filter screen with a filter hole smaller than the particle fat to be filtered. The filter cartridge 63 is installed in the cylinder 62 and there is a gap between the bottom and the inner wall of the cylinder. The top of the filter cartridge 63 is open, and the opening of the filter cartridge 63 is sealed with an end cover 61. The filter cartridge 63 is installed in the cylinder 62, the rear end cover 61 is in a sealed connection with the cylinder 62, the end cover 61 is provided with an inlet and outlet 68; the fat outlet 21 of the fat outlet channel 22 on the fat cutter and the fat collection tank The inlet and outlet 68 of 6 are connected through a connecting pipe 8, the negative pressure generator 94 is connected to a negative pressure tank group through a pipe, and the negative pressure tank group is connected to a negative pressure port 69 of the fat collection tank 6 through a pipe.

In the above embodiment, the outer wall of the cylinder 62 is provided with a self-locking catch 65, the end cover 61 is provided with a sealing gasket 67, and after the filter cartridge 63 is installed in the cylinder 62, the end cover 61 and The opening edge 66 of the cylinder 62 is connected by a sealing gasket 67, and the end cap 61 is pressed against the opening edge 66 of the cylinder 62 through the self-locking buckle 65 on the cylinder 62, so that the end cap 61 and the cylinder 62 are sealed.

In the above embodiment, the fat cutter, the negative pressure generator 94, and the negative pressure tank group are installed on the bracket 9, and the bottom of the bracket 9 is installed with a plurality of universal wheels 91 for support.

In the above embodiment, the filter cartridge includes a lower filter screen and an upper closed cone. The filter screen occupies 1/3 to 3/4 of the height of the entire filter cartridge. There will be a pressure difference between the upper end of the fat and the collection tank, so as to better suck up the water and reduce the excessive water content when injecting fat, which affects the judgment of the injection volume.

The beneficial effects of the invention

Beneficial effect

The fat cutter in the above embodiment changes the inherent clinical thinking of "small diameter and low negative pressure liposuction tube must be used when fat transplantation liposuction", and solves the current dilemma faced by fat transplantation. It has the traction effect of negative pressure. The fat enters the fat inlet channel through the large-caliber liposuction tube, and then the fat flows out from the outlet of the fat inlet channel and is about to fall into the inlet of the fat outlet channel. The fat is cut into smaller particles by a high-speed rotating blade. Small fat particles are sucked out of the device under negative pressure traction. Because the gap between the fat inlet and outlet channels is small, and the negative pressure in the pipeline is greater than or equal to the negative pressure in the cutting device, on the one hand, the fat particles lack the force to leave the pipeline. In this way, the cut fat particles are directly drawn into the fat outlet channel by negative pressure, which minimizes the residue of the fat particles inside the device. On the other hand, it can ensure that the cut fat particles are not cut multiple times and reduce the damage. Destruction of fat particles;

The in-vitro fine particle fat preparation integrated machine in the above embodiment further improves the large-caliber, high negative pressure preparation integrated machine. The suction of the same volume of particle fat ADSCs is 1.7 to 3 times higher than that of the existing preparation method, and more can be obtained. The injected extracellular matrix, in vitro fine particle fat preparation integrated machine uses in vitro fat sucked by the large-caliber liposuction tube to cut and crush the large fat particles into small fat particles, which not only solves the problem caused by excessive fat particles The problem of fat cell necrosis, and solved the problem of low ADSCs content and lack of extracellular matrix in the obtained adipose tissue, while also ensuring cell viability. Experiments also found that the use of large-diameter liposuction tubes can significantly improve the efficiency of clinical liposuction (Up to 3 to 5 times).

In summary, the present invention solves the problems of time-consuming and laborious liposuction during the fat transplantation process, low fat stem cell content, lack of extracellular matrix, and easy pollution during purification. The entire system can also be connected to a liposuction machine to become a liposuction machine. Equipment for fat sculpting.

Brief description of the drawings

Description of the drawings

FIG. 1 is a schematic diagram of the structure of Embodiment 1 of the fat cutter.

Fig. 2 is a schematic diagram of the structure of the upper end cover and the cutting table of the fat cutter embodiment 1.

Fig. 3 is a top view of the cutting table of the fat cutter embodiment 1;

Fig. 4 is a schematic diagram of the structure of the fat cutter embodiment 1 after the cutting table is connected to the controller.

Fig. 5 is a schematic diagram of the structure of Embodiment 2 of the fat cutter.

Fig. 6 is a cross-sectional view of the liposuction tube of the second embodiment of the fat cutter.

Fig. 7 is a schematic diagram of the structure of the fat cutter embodiment 2 connected with the liposuction tube.

Fig. 8 is a schematic diagram of the overall structure of Example 3 of an in vitro fine-particle fat preparation integrated machine.

9 is a schematic diagram of the structure of the fat cutter of Embodiment 3 of the integrated machine for preparing extracorporeal fine-particle fat after being connected to the fat collection tank.

Fig. 10 is a cross-sectional view of the fat collecting tank of Example 3 of the integrated machine for preparing fine-particle fat in vitro.

In the drawings, 1. Upper end cap, 11, grease inlet, 12, grease inlet channel, 13, liposuction pipe, 14, liposuction tube, 141, handle, 1411, deflation channel, 1412, liposuction channel, 1413 , Connecting channel, 1414, air vent, 1415, groove, 142, liposuction needle, 15, cutting groove, 16, step, 17, air inlet, 18, air channel, 19, air release pipe, 2, cutting table , 21, grease outlet, 22, grease channel, 3, cutting device, 31, blade, 32, knife holder, 33, self-locking nut, 34, shaft, 35, bearing, 36, seal ring, 37, buffer coupling Shaft, 38, speed regulating motor, 4, O-ring seal, 5, controller, 51, speed display screen, 52, speed control switch, 53, work indicator light, 54, power switch, 6, collection tank, 61 , End cap, 62, cylinder, 63, filter cartridge, 64, diversion port, 65, self-locking, 66, connecting surface, 67, gasket, 68, inlet and outlet, 69, negative pressure interface, 7, fixed Frame, 8, connecting pipe, 9, bracket, 91, universal wheel, 92, negative pressure tank, 93, quick connection joint, 94, negative pressure generator.

The best embodiment for implementing the invention

The best mode of the present invention

Example 1:

As shown in Figures 1 to 4, a fat cutter includes a cutting table 2 and an upper end cover 1 installed above the cutting table 2. A fat particle cutting device 3 that drives a blade 31 to rotate is installed in the cutting table 2, so The upper end cover 1 is provided with a grease inlet channel 12, the cutting table 2 is provided with a grease outlet channel 22 at a position corresponding to the grease inlet channel 12, and the grease inlet 11 of the grease inlet channel 12 is connected to the grease inlet pipe 13 The large-diameter liposuction tube 14 is connected (the large-diameter liposuction tube 14 here refers to the liposuction channel

The caliber area of the side hole of each liposuction needle is S≥10mm ² ), the length of the liposuction tube 14 is 25-40cm, and the tube diameter is 4-5mm. The liposuction needle of the liposuction tube 14 is provided with 4-6 side holes , The caliber area of each side hole is 20-30mm ² , the grease outlet 21 of the grease outlet channel 22 is connected with a high negative pressure device, and the recommended range of negative pressure provided by the high negative pressure device is 0.06～0.08Mpa , The outlet of the grease inlet channel 12 is arranged opposite to the inlet of the grease outlet channel 22, and the interval matches the thickness of the blade. The outlet of the grease inlet channel 12 is arranged directly above the inlet of the grease outlet channel 22, further, The outlet of the fat inlet channel 12 is coaxially arranged above the inlet of the fat outlet channel 22, and the projection of the outlet of the fat inlet channel 12 on the horizontal plane is within the projection range of the inlet of the fat outlet channel 22 on the horizontal plane, so that the fat enters The outlet of the grease channel 12 directly falls into the inlet of the grease outlet 22 without spillage. The axes of the grease inlet channel 12 and the grease outlet channel 22 are arranged in parallel with the axis of rotation of the blade 31 to ensure that the cutting edge of the blade is perpendicular to the axis Cutting to ensure the effect of cutting.

The fat particle cutting device 3 includes a blade 31, a blade holder 32, a shaft, and a speed-regulating motor 38. The blade 31 is installed on the blade holder 32, and the blade 31 and the blade holder 32 are fixed on the shaft by a self-locking nut 33. The shaft is mounted on the cutting table 2 through a bearing 35, and is arranged coaxially with the central axis of the cutting table. The bearing 35 and the cutting table 2, the shaft and the cutting table 2 are sealed by a sealing ring 36, and the shaft It is connected to the speed regulating motor 38 through a buffer coupling 37.

The speed control motor 38 is electrically connected to the controller 5, and the controller 5 includes a speed display screen 51 that displays the speed of the speed control motor 38, a speed control switch 52 that adjusts the speed of the speed control motor 38, and a speed control switch 52 that displays the status of the speed control motor 38. The work indicator light 53 and the power switch 54 that controls and adjusts the opening and closing of the motor.

An O-shaped sealing ring 4 is installed in the fixed side of the cover body of the upper end cover 1. After the upper end cover 1 is connected with the cutting table 2, the O-shaped sealing ring 4 is sealed and connected. After the upper end cover 1 is installed on the cutting table 2, all Between the upper end cover 1 and the cutting table 2, in the area where the outlet of the fat inlet channel 12 and the inlet of the fat outlet channel 22 are provided, there are spaced annular cutting grooves 15, and the blade 31 of the fat particle cutting device 3 is arranged in the cutting groove 15 In this embodiment, the height of the cutting groove 15 is 2 to 4 mm, which can accommodate at least one blade. The blade is maintained at a speed of 2500-3000 rpm. The height of the cutting groove 15 is such that the blade will not interfere with the cutting when rotating at high speed. Slot 15 interferes. Through the above structure, the diameter of the fat particles obtained by cutting is less than or equal to 2 mm, which can effectively avoid the necrosis of the transplanted fat center caused by the excessively large particles.

As another embodiment of the device, a set of blades 31 are arranged between the outlet of the grease inlet channel 12 and the inlet of the grease outlet channel 22, and adjacent blades 31 are along the outlet of the grease inlet channel 12 and the inlet of the grease outlet channel 22. It is arranged in the connection direction. When the fat enters the cutting groove 15, it is cut by the high-speed rotating blade and is quickly discharged by suction, avoiding multiple cuts and reducing the damage to the fat particles.

In this embodiment, the grease inlet 11 of the grease inlet channel 12 and the grease outlet 21 of the grease outlet channel 22 are provided with a quick connection joint 93. This facilitates the quick connection and disassembly of the pipeline and the device.

In this embodiment, the high negative pressure can be achieved by using a hospital negative pressure suction system, or by separately configuring a negative pressure generator and a negative pressure tank.

When this embodiment is used for fat preparation, the negative pressure system is connected to the fat outlet of the device. Under the traction of the negative pressure, the fat enters the fat inlet channel 12 through the large-diameter liposuction tube, and then the fat enters the fat inlet channel 12 When the exit of 12 enters the cutting groove 15 and is about to fall into the entrance of the fat exit channel 22, it is cut into smaller particles by the high-speed rotating blade of the fat particle cutting device 3, and the small particles of fat after the cut are drawn from the device under the negative pressure. It is sucked out, which completes the cutting of fat.

Invention embodiment

Embodiments of the present invention

Example 2:

As shown in Figures 5 to 7, a fat cutting device. The difference between Embodiment 2 and Embodiment 1 is that the liposuction tube 14 includes a handle 141 and a liposuction needle 142, and a liposuction channel 1412 is provided in the handle 141. And a deflation channel 1411, the liposuction needle 142 is installed on the entrance of the liposuction channel 1412, the upper end cover 1 is also provided with an air guide channel 18 communicating with the cutting groove 15, and the handle 141 is also provided with A connecting passage 1413 is provided with a vent hole 1414 on the outside of the handle 141, the front end of the vent passage 1411 communicates with the middle of the connecting passage 1413, and one end of the connecting passage 1413 communicates with the vent hole 1414 provided on the handle 141, The other end is in communication with the middle of the liposuction channel 1412, and an angle is provided between the connection channel 1413 and the liposuction channel 1412 to prevent fat from entering the connection channel 1413 from the liposuction channel 1412, and the outlet end of the deflation channel 1411 passes through a deflation tube 19 is connected with the air inlet of the air guide channel of the housing.

In this embodiment, the handle 141 is provided with a liposuction needle 142 connector on the inlet end of the liposuction channel 1412, and the handle 141 is provided with a liposuction pipe 13 joint on the outlet end of the liposuction channel 1412. The outlet end of the channel 1411 is provided with a vent tube 19 joint. The angle between the connecting channel 1413 and the liposuction channel 1412 is an acute angle facing the side of the connection head of the liposuction needle 142, and the acute angle is preferably 45 degrees. The needle 142 connector, the liposuction pipe 13 connector and the vent pipe 19 connector are all quick connectors.

In this embodiment, the handle 141 is provided with a groove 1415 in the area where the air release hole 1414 is located to facilitate the pressing and sealing of the thumb of the thumb. The inner wall of the cutting groove 15 and the inner wall of the fat outlet channel 22 are covered with soft For the material layer, the inner wall of the step 16, the connection between the step 16 and the outlet of the cutting groove 15, and the connection between the step 16 and the inlet of the grease channel 22 are all curved surfaces.

Example 3:

As shown in Figure 8 to Figure 10, an in vitro fine particle fat preparation integrated machine, including a fat collection tank 6, a bracket 9 and a fat cutter installed on the bracket, a negative pressure generator 94, a negative pressure tank group 92, the fat The cutter is installed on the bracket 9 through the fixing frame 7, and the fat cutter includes the fat cutter in Example 1 and Example 2;

As shown in Figure 10, the fat collection tank 6 includes a cylinder 62 and a filter cartridge 63. The top of the cylinder 62 is open, and the bottom of the cylinder 62 is provided with a negative pressure interface 69 to communicate with the inner cavity of the cylinder 62. The filter cartridge 63 It is composed of a filter screen with a filter hole diameter smaller than that of the particulate fat to be filtered. The filter cartridge 63 is installed in the cylinder 62 and there is a gap between the bottom and the inner wall of the cylinder. The top of the filter cartridge 63 is open, and the filter cartridge 63 An end cap 61 is installed on the opening of the filter cartridge 63 in a sealed manner. The end cap 61 is provided on one side of the filter cartridge 63 with an inclined surface with the inlet and outlet 68 as the inclined center to form a conical diversion port whose bottom surface matches the diameter of the filter cartridge 63 64. In this embodiment, the aperture of the inlet and outlet is about 4-6mm. The design of the diversion port on the end cap allows the fat to be discharged through the diversion port when the fat is taken out, which prevents the fat from being stuck in the corners during the lead-out process and causing loss; the fat outlet 21 of the fat outlet 22 The inlet and outlet 68 of the fat collection tank 6 are connected through the connecting pipe 8; the negative pressure generator 94 is connected to the negative pressure tank group 92 through the pipe, and the negative pressure tank group 92 is connected to the negative pressure interface of the fat collection tank 6 through the pipe 69 connection, the end of the negative pressure tank group 92 for connecting with the fat collection tank 6 is provided with a quick connection joint 93. The negative pressure generator 94 provides negative pressure so that the negative pressure at the liposuction end of the liposuction tube 14 ranges from 0.06 to 0.08 Mpa.

As another embodiment of the fat collection tank, the filter cartridge 63 includes a lower filter screen and an upper closed cone. The filter screen occupies 1/3 to 3/4 of the height of the entire filter cartridge, so that when the fat is sucked When it exceeds the mesh part, there will be a pressure difference between the upper end of the fat and the collection tank, so as to better suck up the water and reduce the excessive water content when injecting the fat, which affects the judgment of the injection volume.

The outer wall of the cylinder 62 is provided with a self-locking catch 65, the end cover 61 is provided with a sealing gasket 67, and the filter cartridge 63 is installed in the cylinder 62, the end cover 61 and the opening edge of the cylinder 62 66 is connected by a sealing gasket 67, and the end cap 61 is pressed against the opening edge 66 of the cylinder 62 through the self-locking buckle 65 on the cylinder 62, so that the end cap 61 and the cylinder 62 are sealed, and the end cap 61 is An inlet and outlet 68 are provided. After the end cover 61 is sealed with the cylinder 62, the inlet and outlet 68 communicate with the negative pressure port 69 through the filter cartridge 63. The end cover is reliably fixed on the cylinder body through a structure such as a sealing gasket and a self-locking button to ensure the internal sealing and the normal operation of the negative pressure system. The negative pressure interface 69 of the fat collecting tank 6 and the inlet and outlet 68 on the end cover 61 are provided with a quick connection joint 93.

When this embodiment is in use, when the negative pressure generator 94 is activated, under the traction of the negative pressure, the fat enters the fat inlet channel 12 through the large-caliber liposuction tube, and then the fat enters the cutting groove 15 from the outlet of the fat inlet channel 12 In the process of falling into the entrance of the fat outlet channel 22, the fat particle cutting device 3 is cut into smaller particles by the high-speed rotating blade. The cut small fat particles are sucked out from the fat outlet of the device under negative pressure and pass through the fat. The inlet and outlet of the collection tank enter the filter cartridge 63, and the filtered blood water and other liquids are sucked into the negative pressure tank under negative pressure traction. After liposuction is completed, take out the filter cartridge 63 and the end cap 61 from the cylinder 62 together, use a cotton pad or gauze to absorb water through the filter cartridge net, and then fix the end cap 61 and the filter cartridge 63 on the cylinder body. 62, after being locked by the self-locking buckle, the filter cartridge 63 is turned over, and the fat is sucked into the syringe through the inlet and outlet for fat injection into the body.

Industrial applicability

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Sequence Listing Free Content

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Claims

A fat cutter, which is characterized in that it comprises a fat inlet channel (12), a fat outlet channel (22), and at least one set of blades arranged between the outlet of the fat inlet channel (12) and the inlet of the fat outlet channel (22). 31) and a housing that seals the space where the grease inlet channel (12) is located, the inlet of the grease outlet channel (22) and the blade (31), and the grease inlet (11) of the grease inlet channel (12) is connected to the large The fat suction tube (14) of caliber is connected, and the fat outlet (21) of the fat outlet channel (22) is connected with the high negative pressure device,

The outlet of the grease inlet channel (12) and the inlet of the grease outlet channel (22) are arranged opposite to each other, and there is an interval between the two to form a cutting groove matching the thickness of the blade, and the outlet of the grease inlet channel (12) is arranged Above the inlet of the fat outlet channel (22), in the working state, the cutting edge of the blade (31) passes through the line connecting the outlet of the fat inlet channel (12) and the inlet of the fat outlet channel (22) to cut fat particles.
The fat cutter according to claim 1, wherein the housing includes a cutting table (2) and an upper end cover (1) installed above the cutting table (2), and the cutting table (2) is installed in A fat particle cutting device (3) with a drive blade group, the upper end cover (1) is provided with a fat inlet channel (12), and the cutting table (2) is provided at a position corresponding to the fat inlet channel (12) Grease outlet channel (22), the upper end cover (1) is sealed and installed on the cutting table (2) by a seal to form an assembled state. In the assembled state, between the upper end cover (1) and the cutting table (2) , The area where the outlet of the fat inlet channel (12) and the inlet of the fat outlet channel (22) are provided with circular cutting grooves at intervals, and the blade group of the fat particle cutting device (3) is arranged in the cutting groove.
The fat cutter according to claim 2, wherein the outlet of the fat inlet channel (12) is coaxially arranged directly above the inlet of the fat outlet channel (22), and the outlet of the fat inlet channel (12) is located at The projection on the horizontal plane is within the projection range of the entrance of the grease outlet channel (22) on the horizontal plane, and the axes of the grease inlet channel (12) and the grease outlet channel (22) are arranged parallel to the axis of rotation of the blade (31).
The fat cutter according to claim 3, characterized in that the cutting edge and the cutting surface of the blade (31) are perpendicular to the axes of the fat inlet channel (12) and the fat outlet channel (22).
The fat cutter according to claim 2, wherein the height of the cutting groove is 2 to 4 mm.
The fat cutter according to claim 2, characterized in that: the fat particle cutting device (3) comprises a blade (31), a knife holder (32), a shaft and a speed regulating motor (38), and the blade (31) ) Is installed on the knife holder (32), and the blade (31) and the knife holder (32) are fixed on the shaft through a self-locking nut (33), and the shaft is installed on the cutting table (2) through a bearing (35) , The bearing (35) and the cutting table (2), the shaft and the cutting table (2) are sealed by a sealing ring (36), and the shaft is connected to the speed regulating motor (38) through a buffer coupling (37) .
The fat cutter according to claim 6, characterized in that: the speed-regulating motor (38) is electrically connected to a controller (5), and the controller (5) includes a speed indicating the speed of the speed-regulating motor (38) A display screen (51), a speed control switch (52) for adjusting the speed of the speed control motor (38), a work indicator light (53) for displaying the state of the speed control motor (38), and a power switch (54) for controlling the opening and closing of the adjustment motor.
The fat cutter according to claim 1, wherein the rotation speed of the blade (31) is 2500-3000 rpm.
The fat cutter according to claim 1, wherein the liposuction tube (14) includes a handle (141) and a liposuction needle (142), and a liposuction channel (1412) is provided in the handle (141). ) And a venting channel (1411), the housing is also provided with an air guiding channel (18), the air guiding channel (18) is in communication with the cutting groove (15), and the outlet of the liposuction channel (1412) passes through the suction The grease pipe (13) is connected with the grease inlet (11) of the grease inlet channel (12) of the housing, the handle (141) is also provided with a connecting channel (1413), and the handle (141) is provided with a vent hole on the outside (1414), the front end of the deflation channel (1411) is in communication with the connecting channel (1413), one end of the connecting channel (1413) is in communication with the deflation hole (1414) provided on the handle (141), and the other end It is connected to the liposuction channel (1412), and there is an angle between the connecting channel (1413) and the liposuction channel (1412) to prevent the sucked fat from entering the connecting channel (1 413) from the liposuction channel (1412), so The outlet end of the air release channel (1411) is connected with the air inlet of the air guide channel (18) of the housing through an air release pipe (19).
The fat cutting device according to claim 9, characterized in that the angle between the connecting channel (1413) and the liposuction channel (1412) facing the connecting head of the liposuction needle (142) is an acute angle.
The fat cutting device according to claim 9, characterized in that the handle (141) is provided with a groove (1415) in the area where the air release hole (1414) is located to facilitate the pressing and sealing of the thumb of the thumb.
The fat cutting device according to claim 1, wherein the inner wall of the cutting groove (15) and the inner wall of the entrance of the fat outlet channel (22) are covered with a soft material layer.
The fat cutting device according to claim 1, characterized in that the inlet of the fat outlet channel (22) is smaller than the outlet of the cutting groove (15) to form a step (16), and the inner wall and the step (16) of the step (16) 16) The connection between the outlet of the cutting groove (15) and the connection between the step (16) and the inlet of the grease outlet channel (22) are all curved surfaces.
An in vitro fine particle fat preparation integrated machine, characterized in that it comprises the fat cutter according to any one of claims 1 to 13, and further comprises a fat collection tank (6), a negative pressure generator (94) and a negative pressure tank group,

The fat collection tank (6) includes a cylinder (62) and a filter cartridge (63). The top of the cylinder (62) is open, and the bottom is provided with a negative pressure interface (69) to communicate with the inner cavity of the cylinder (62) The filter cartridge (63) is composed of a filter screen with a filter hole diameter smaller than the particle fat to be filtered. The filter cartridge (63) is installed in the cylinder body (62) and has a gap between the bottom and the inner wall of the cylinder. The top of the filter cartridge (63) is open, the opening of the filter cartridge (63) is sealed and installed with an end cover (61), and the filter cartridge (63) is installed on the inner rear end cover (61) of the cylinder body (62) and The cylinder body (62) is connected in a sealed manner, the end cap (61) is provided with an inlet and outlet (68); the fat outlet (21) of the fat outlet channel (22) on the fat cutter is connected to the fat collecting tank (6) The inlet and outlet (68) of) are connected by a connecting pipe (8), the negative pressure generator (94) is connected to the negative pressure tank group through the pipeline, and the negative pressure tank group is connected to the negative pressure tank group through the pipe. The pressure port (69) is connected.
An in vitro fine particle fat preparation integrated machine according to claim 14, characterized in that: the fat cutter, negative pressure generator (94), and negative pressure tank group are installed on the bracket (9), and the fat The cutter is installed on the bracket (9) through a fixing frame (7), and a plurality of universal wheels (91) for supporting are installed at the bottom of the bracket (9).
The in vitro fine particle fat preparation integrated machine according to claim 14, characterized in that: the outer wall of the cylinder (62) is provided with a self-locking button (65), and the end cover (61) is provided with a seal A gasket (67), after the filter cartridge (63) is installed in the cylinder (62), the end cap (61) and the opening edge (66) of the cylinder (62) are connected by a gasket (67), and pass The self-locking buckle (65) on the cylinder body (62) and the end cover (61) are pressed tightly on the opening edge (66) of the cylinder body (62), so that the end cover (61) and the cylinder body (62) are sealed.
The in-vitro fine particle fat preparation integrated machine according to claim 14, characterized in that: the filter cartridge comprises a lower filter screen and an upper closed conical tube, and the filter screen occupies 1/3 ~ of the height of the entire filter cartridge. 3/4.