CN109692207A - Realize the plant composition of deep burn subcrustal healing - Google Patents
Realize the plant composition of deep burn subcrustal healing Download PDFInfo
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- CN109692207A CN109692207A CN201811635009.4A CN201811635009A CN109692207A CN 109692207 A CN109692207 A CN 109692207A CN 201811635009 A CN201811635009 A CN 201811635009A CN 109692207 A CN109692207 A CN 109692207A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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Abstract
The invention belongs to pharmaceutical technology fields, are related to a kind of plant composition for realizing deep burn subcrustal healing, including rabdosia lophanthide, rheum officinale, borneol and fruits of elm, and parts by weight are 0.1~50 part.The curative effect that botanical herbs provided by the invention can play heat-clearing with burn, dissipate the stasis of blood, hemostasis, detoxify, prevent infection, burn incrustation can obtain good wound healing, and safety is without side-effects.
Description
Technical field
The invention belongs to pharmaceutical technology fields, are related to a kind of plant composition for realizing deep burn subcrustal healing.
Background technique
Burn refers to the damage occurred by body contact high temperature, electric current, intense radiation or corrosive substance.Wherein,
Heat injury is most common and most important traumatogenic reason, accounts for about and always accepts the 89% of the wounded for medical treatment, common are flame, smog, heat
Water, the semifluid of hydrothermal solution and heat, semisolid, solid etc., pediatric burn are again more with scald caused by hydrothermal solution, steam；Chemistry is burnt
Wound can result in skin and the chemical classes of subcutaneous deep tissues damage are various, it is main just like acid, alkali, benzene, phosphorus etc. and
Their derivative etc.；Electric burn refers to function of current damage caused by human body surface and deep tissue.Its degree damaged
With the type of electric current, the height of voltage, approach of the electric current in human body, the state of insulation of human body, the length of time with galvanic contact
It is related.
To the severity of burn, three degree of quarterings is mostly used to be judged at present: (1) I degree (erythematous): part is like red
Spot, mild redness, no blister is dry, and no infection, skin burns sample pain.Resolution of symptoms in general 2~3 days, 3~5 days
Interior recovery from illness, does not stay spot；(2) II degree (vesiculovirus): being divided into Superficial bums and deepⅱdegreeburn.Superficial bums: have larger
Bubble, oedema are not complicated by infection such as with severe pain, dermal sensation allergy, are healed within 2 weeks or so, are not stayed scar, in a short time visible pigment
It is calm；(3) deepⅱdegreeburn: bubble is smaller, oedema, and dermal sensation is blunt.It generally needs fully recover within 3~4 weeks, has scar after healing；
(4) III degree (eschar): ochrodermia or sallow charing, dry, hide-like, dermal sensation is blunt, and pain is unobvious；The surface of a wound is cured
Conjunction is slower, and majority needs to make skin graft, and there are scar or/and deformities after healing.
The early stage of burn, which is correctly handled, can mitigate burn degree, reduce the incidence and the death rate of complication, be burn
The basis of patient's successive treatment, but the later period burnt restores and the healing of wound is also very important, and especially burns
Incrustation healing plays conclusive effect to the recovery of wound.Subcrustal healing (healing under-scab) is a kind of special item
The peculiar healing mode of wound under part refers to after the tissue of wound surface to be fallen off by diffusate, blood and necrosis is dry
The healing by second intention process carried out under the one layer of hard scab of brown formed, such as being cured under the hard scab of leather sample after deep two degree or third-degree burn
Conjunction process belongs to such, long compared with no scab person the time required to subcrustal healing under normal conditions, because promoting epidermization at this time must be first
First crust is dissolved, then could be grown forward.Though crust is unfavorable for the growth of bacterium because dry, there is certain guarantor to wound
Shield effect, but exudate is more under the scab, especially when existing bacterium infection, crust but becomes the obstacle of diffusate drainage, at
For " culture medium " under scab, bacterium infection is often aggravated, and influences its agglutination, therefore often needs to implement " cutting scab " or " cutting scab " operation,
To expose the surface of a wound, form epidermis quickly, but often result in the formation of hyperplastic scar, influence it is beautiful even make function by
Limit.And realizing perfect subcrustal healing becomes problem.
Summary of the invention
The purpose of the present invention is to solve the bacterium infections of wound when subcrustal healing, it is intended to propose that a kind of realization depth is burnt
Hurt the plant composition of subcrustal healing, so that wound healing under scab, and safety is without side-effects.
The technical solution adopted by the present invention are as follows:
A kind of plant composition for realizing deep burn subcrustal healing, it is characterised in that: under the realization deep burn scab
The plant composition of healing includes rabdosia lophanthide, rheum officinale, borneol and fruits of elm.
The parts by weight of above-mentioned rabdosia lophanthide, rheum officinale and borneol are 0.1~50 part.
The plant composition of above-mentioned realization deep burn subcrustal healing further includes rhizoma nelumbinis.
The parts by weight of above-mentioned rhizoma nelumbinis are 0.1~50 part.
The plant composition of above-mentioned realization deep burn subcrustal healing further includes pine needle.
The parts by weight of above-mentioned pine needle are 0.1~50 part.
The sum of the parts by weight of both medicines of above-mentioned rabdosia lophanthide and rheum officinale are these four medicines of borneol, fruits of elm, rhizoma nelumbinis and pine needle
3~8 times of the sum of parts by weight.
The sum of the parts by weight of both medicines of above-mentioned rabdosia lophanthide and rheum officinale are these four medicines of borneol, fruits of elm, rhizoma nelumbinis and pine needle
5 times of the sum of parts by weight.
Above-mentioned borneol, fruits of elm, the weight ratio of rhizoma nelumbinis and pine needle these four medicines are 1:1:1:1.
Technical advantage of the invention are as follows: the botanical herbs that the present invention uses, rabdosia lophanthide have clearing heat and promoting diuresis, removing jaundice clearing damp,
The effect of cool blood dissipates the stasis of blood, for treating the illnesss such as bruise stasis caused pain；Rheum officinale cures mainly traumatic injury, suitable amount used externally, control scald, on
Hemorrhage of digestive tract；Borneol goes screen improving eyesight, and swelling and pain relieving controls boiling hot, burn；Fruits of elm clearing away heat and promoting diuresis, desinsection detumescence, oedema, children's infantile malnutrition due to digestive disturbances or intestinalparasites
Hot thin thin, burn and scald, the illnesss such as ringworm sore；Rhizoma nelumbinis is medicinal can to shorten the bleeding time, there is the benefits of hemostasis scattered silt, ripe to use help spleen
Stomach, beneficial blood myogenic；Health product clearing heat and promoting fluid, cooling blood and hemostasis；Pine needle expelling wind and activating blood flow, removing toxic substances is antipruritic, is used for treating swelling and pain by traumatic injury.The present invention
Use rabdosia lophanthide, rheum officinale for monarch, borneol, fruits of elm are minister, rhizoma nelumbinis is assistant, and pine needle is to make, this plant composition Chinese medicine can be to burning
The curative effect that wound plays heat-clearing, dissipates the stasis of blood, hemostasis, detoxifies, preventing infection, safety is without side-effects, and incrustation burn can obtain well
Healing.
Specific embodiment
The present invention is described in detail now in conjunction with embodiment.
Rabdosia lophanthide (Rabdosia serra (Maxim.) Hara) is traditional herbal medicine, is commonly called as wintergreen barberry root etc., has heat-clearing benefit
The effect of wet, removing jaundice clearing damp, cool blood dissipates the stasis of blood, for treating acute icteric hepatitis, acute cholecystitis, dysentery, enteritis, the bruise stasis of blood
The illnesss such as pain.
Rheum officinale, taste bitter and cold, purgating heat and bowels, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, with controlling real heat constipation, stagnant abdominal pain, dysentery not
Refreshing, jaundice with damp-heat pathogen, blood-head tells nosebleed, hot eyes, pharynx swelling, acute appendicitis furunculosis, blood stasis closed, traumatic injury, suitable amount used externally are harnessed the river burning hot
Wound, upper gastrointestinal bleeding.
Borneol also known as piece brain, orange slices, kapur, MEIHUA BINGPIAN, Dipterocarpus pilosus, plum blossom brain, borneol brain, Mei Bing etc., nature and flavor
It is bitter cool, lead to all keys, dissipates stagnated fire, go screen improving eyesight, swelling and pain relieving controls apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm confusing heart, deafness with qi stagnation, larynx
Numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen film, enterobiasis.Control boiling hot, burn.
Fruits of elm, mild-natured, sweet in flavor, micro-pungent, spleen-benefiting mind-tranquilizing, clearing heart fire is relieving cough and reducing sputum, clearing away heat and promoting diuresis, desinsection detumescence.It cures mainly
Insomnia, loss of appetite, leukorrhagia, difficult urination, oedema, fever in infantile malnu is thin thin, burn and scald, the illnesss such as ringworm sore.
Rhizoma nelumbinis is mild-natured, sweet-puckery flavor, medicinal to shorten the bleeding time, there is the benefits of hemostasis scattered silt, ripe with strengthening the spleen and stomach, beneficial blood
Myogenic；Health product clearing heat and promoting fluid, cooling blood and hemostasis.
Pine needle bitter and puckery flavor, warm-natured, expelling wind and activating blood flow, improving eyesight are calmed the nerves, and removing toxic substances is antipruritic, are eliminated bad breath, are gone mouth parched and tongue scorched, control just
It is secret.For treating swelling and pain by traumatic injury, yctalopia, high blood pressure, neurasthenia；External application treating chilblain.
Above-mentioned effect based on plant, the plant composition of realization deep burn subcrustal healing of the invention, including small stream are yellow
Grass, rheum officinale, borneol and fruits of elm.Rabdosia lophanthide, rheum officinale, borneol and fruits of elm parts by weight be 0.1~50 part.Realize that depth is burnt
The plant composition for hurting subcrustal healing further includes rhizoma nelumbinis.The parts by weight of rhizoma nelumbinis are 0.1~50 part.Realize deep burn subcrustal healing
Plant composition further include pine needle.The parts by weight of pine needle are 0.1~50 part.The weight of both medicines of above-mentioned rabdosia lophanthide and rheum officinale
Part the sum of be 3~8 times of the sum of parts by weight of borneol, fruits of elm, rhizoma nelumbinis and pine needle these four medicines.Rabdosia lophanthide and rheum officinale both medicines
The sum of parts by weight be 5 times of the sum of parts by weight of borneol, fruits of elm, rhizoma nelumbinis and pine needle these four medicines.Borneol, fruits of elm, rhizoma nelumbinis and
The weight ratio of these four medicines of pine needle is 1:1:1:1.
According to above-mentioned floristics and dosage, the burn subcrustal healing of following various combination and dosage is prepared in selection
Treatment of the composition for burn.
Embodiment 1
7 kinds of plant compositions are prepared according to the parts by weight that experiment 1 in table 1~experiment 7 provides, randomly select any group of (this
Selection experiment 5 in embodiment) 21 are directed to because the patient for having different burn surface areas, different depth to burn caused by fire controls
It treats, patient is randomly divided into 3 groups, every group of 7 people (men and women is random).Powder is ground in use, plant composition is put into mortar
Powder is directly applied to affected part by shape；One day once in the morning and once at night；Even apply 14 days；Wound after observing patient's use, which is formed a scab, to be changed.
Final result shows, discovery patient symptom is happened without infection, and diet is normal, and basic no pain occurs, wound substantially without
It suppurates phenomenon, is not required to escharectomy, cure rate 64.7% substantially.
Embodiment 2
7 kinds of plant compositions are prepared according to the parts by weight that experiment 8 in table 1~experiment 14 provides, randomly select any group of (this
Selection experiment 11 in embodiment) for 28 patient's progress because thering are different burn surface areas, different depth to burn caused by gas
Treatment, selects 28 fire victims and patient is randomly divided into 4 groups, every group of 7 people.In use, plant composition is put into mortar
In be ground to powdery, powder is directly attached to patient part in paste by the preparation of existing preparation method；One day morning and evening each one
It is secondary；Even apply 10 days；Wound after observing patient's use, which is formed a scab, to be changed.Final result shows that discovery patient symptom is without infection feelings
Condition occurs, and diet is normal, and no pain occurs, wound without phenomenon of suppurating, be not required to escharectomy can in decrustation realization table
Skin healing, cure rate 81.3%.
Embodiment 3
7 kinds of plant compositions are prepared according to the parts by weight that experiment 15 in table 1~experiment 21 provides, randomly select any group
(Selection experiment 19 in the present embodiment) is for 13 because the patient for having different burn surface areas, different depth to burn caused by fire carries out
Treatment selects 13 fire victims and patient is randomly divided into 2 groups, first group of 8 people, second group of 5 people.In use, by plant group
Conjunction object, which is put into mortar, is ground to powdery, and powder is directly attached to patient part in paste by the preparation of existing preparation method；
One day once in the morning and once at night；Even apply 12 days；Wound after observing patient's use, which is formed a scab, to be changed.Final result is shown, in two groups of patients
Symptom is happened without infection, and diet is normal, and no pain occurs, and wound phenomenon and is clearly better without suppurating, cure rate
87.2%.
To 1~embodiment of embodiment 3 to the treatment condition of patients with deep burn subcrustal healing, it is necessary to containing with rabdosia lophanthide and
Rheum officinale is monarch, and borneol and fruits of elm are the plant composition of minister, can play detumescence to burn, analgesic, dissipate the effect of stasis of blood, so that wound
Quickly incrustation；When adding rhizoma nelumbinis and pine needle in plant composition, can quick-acting haemostatic powder, myogenic, antipruritic effect, burn scab under more
Conjunction degree is more preferable.
Embodiment 4
6 kinds of plant compositions are prepared according to the parts by weight that experiment 22 in table 1~experiment 26 provides, wherein rabdosia lophanthide and rheum officinale
The sum of parts by weight of both medicines are 1 times, 3 times, 5 of the sum of parts by weight of borneol, fruits of elm, rhizoma nelumbinis and pine needle these four medicines respectively
Again, 8 times, 10 times；It selects 18 fire victims and patient is randomly divided into 6 groups, every group of 3 people；Experiment 22 is used for the 1st group of burn
The treatment of patient, experiment 23 are used for the treatment ... of the 2nd group of fire victim, and so on, experiment 26 is used for the 6th group of fire victim
Treatment, observe patient's use after wound form a scab variation.It is ground to powdery in use, plant composition is put into mortar,
Powder is directly applied to affected part；One day once in the morning and once at night；Even apply 12 days；The symptom discovery for observing patient, when rabdosia lophanthide and greatly
The sum of the parts by weight of both yellow medicines are the sum of parts by weight of borneol, fruits of elm, rhizoma nelumbinis and pine needle these four medicines at 3~8 times, special
Be not rabdosia lophanthide and rheum officinale both medicines the sum of parts by weight be borneol, fruits of elm, the parts by weight of rhizoma nelumbinis and pine needle these four medicines it
At 5 times of sum, patient symptom is happened without infection, and diet is normal, hence it is evident that no pain occurs, wound without phenomenon of suppurating, and
Without itch phenomenon, scab lower epidermis regenerates more perfect, cure rate 92.4%.
Embodiment 5
According to testing 27 in table 1, the parts by weight that experiment 28 and experiment 29 provide prepare plant composition, wherein rabdosia lophanthide
The sum of parts by weight with rheum officinale both medicines are 5 times of the sum of parts by weight of borneol, fruits of elm, rhizoma nelumbinis and pine needle these four medicines, and
Borneol, fruits of elm, the weight ratio of rhizoma nelumbinis and pine needle these four medicines are 1:1:1:1；Random selection test 28 is as 12 burns
The treatment of patient.It is ground to powdery in use, plant composition is put into mortar, powder is prepared by existing preparation method
Patient part is directly attached in paste；One day once in the morning and once at night；Even apply 10 days；Wound after observing patient's use, which is formed a scab, to be become
Change.Patient symptom is happened without infection, and diet is normal, hence it is evident that no pain occurs, and wound shows without phenomenon of suppurating, and without itch
As whole cure rate 96.3%.Plant composition at this time is best to deep burn subcrustal healing effect.According to the present invention group
Part prepares plant, and composition is directly prepared into powdery or paste is applied to the affected area of deep second degree burn, observes different time
Lesion variation, it can be seen from the figure that having there is within lesion 7 days the healing of scab lower epidermis, the healing of 14 days epidermises is good.
Claims (6)
1. a kind of plant composition for realizing deep burn subcrustal healing, it is characterised in that: under the realization deep burn scab more
The plant composition of conjunction includes rabdosia lophanthide, rheum officinale, borneol and fruits of elm；The rabdosia lophanthide, rheum officinale, borneol and fruits of elm weight
Part is 0.1~50 part.
2. the plant composition according to claim 1 for realizing deep burn subcrustal healing, it is characterised in that: the realization
The plant composition of deep burn subcrustal healing further includes rhizoma nelumbinis；The parts by weight of the rhizoma nelumbinis are 0.1~50 part.
3. the plant composition according to claim 2 for realizing deep burn subcrustal healing, it is characterised in that: the realization
The plant composition of deep burn subcrustal healing further includes pine needle；The parts by weight of the pine needle are 0.1~50 part.
4. the plant composition according to claim 3 for realizing deep burn subcrustal healing, it is characterised in that: the small stream is yellow
The sum of the parts by weight of grass and both medicines of rheum officinale are the 3~8 of the sum of borneol, fruits of elm, the parts by weight of rhizoma nelumbinis and pine needle these four medicines
Times.
5. the plant composition according to claim 4 for realizing deep burn subcrustal healing, it is characterised in that: the small stream is yellow
The sum of the parts by weight of grass and both medicines of rheum officinale are 5 times of the sum of borneol, fruits of elm, the parts by weight of rhizoma nelumbinis and pine needle these four medicines.
6. the plant composition according to claim 5 for realizing deep burn subcrustal healing, it is characterised in that: the ice
Piece, fruits of elm, the weight ratio of rhizoma nelumbinis and pine needle these four medicines are 1:1:1:1.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1228981A (en) * | 1998-06-04 | 1999-09-22 | 韦明 | Scald powder |
-
2018
- 2018-12-29 CN CN201811635009.4A patent/CN109692207A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1228981A (en) * | 1998-06-04 | 1999-09-22 | 韦明 | Scald powder |
Non-Patent Citations (5)
| Title |
|---|
| 《收藏经典版》编委会: "《健康食疗大全集》", 31 January 2011, 湖南美术出版社 * |
| 刘绍贵等: "《临床常用中草药鉴别与应用》", 31 July 2015, 湖南科学技术出版社 * |
| 新浪博客: "无", 《HTTP://BLOG.SINA.COM.CN/S/BLOG_3CB56B900100ZBUX.HTML》 * |
| 苗明三等: "《中药大辞典》", 30 June 2017, 山西科学技术出版社 * |
| 陈达灿等: "《临床常见伤口护理》", 31 March 2016, 中国医药科技出版社 * |
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