CN109675006A - A kind of prevention and treatment cancer cell and the composition of cardiovascular disease and preparation method thereof - Google Patents

A kind of prevention and treatment cancer cell and the composition of cardiovascular disease and preparation method thereof Download PDF

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CN109675006A
CN109675006A CN201910108166.8A CN201910108166A CN109675006A CN 109675006 A CN109675006 A CN 109675006A CN 201910108166 A CN201910108166 A CN 201910108166A CN 109675006 A CN109675006 A CN 109675006A
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garlic
ginger
green onion
extracting solution
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王景胜
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The present invention relates to health care product technical fields, disclose a kind of prevention and treatment cancer cell and the composition of cardiovascular disease and preparation method thereof, the composition includes green onion, ginger and garlic extracting solution, lobelia chinensis, erigeron breviscapus, Radix Glycyrrhizae, selenium-rich garlic, traditional Chinese medicine of the five flavours extracting solution, eclipta, Schisandra chinensis, ginkgo leaf and starch, raw material in formula is respectively as follows: green onion, ginger and garlic extracting solution 15%-25% by weight ratio, lobelia chinensis 2%-4%, erigeron breviscapus 2%-5%, Radix Glycyrrhizae 2%-4%, selenium-rich garlic 7%-10%, traditional Chinese medicine of the five flavours extracting solution 35%-41%, eclipta 3%-8%, Schisandra chinensis 2%-5%, ginkgo leaf 2%-5% and starch 16%-25%.By taking this composition; it is improved heart to the conveying function of blood; the hematopoiesis function of liver gets a promotion; the viscosity for reducing blood, is improved the dilatancy of blood vessel, and the multiple necessary conditions for generating thrombus are removed on body; dispel thrombus; it avoids that thrombus condensation occurs, protects body internal organs, the cardiovascular disease that can without adverse affects generate to thrombus is treated and prevented and treated.

Description

A kind of prevention and treatment cancer cell and the composition of cardiovascular disease and preparation method thereof
Technical field
The present invention relates to health care product technical field, specially a kind of composition for preventing and treating cancer cell and cardiovascular disease And preparation method thereof.
Background technique
With the continuous improvement of living standards, excessive heat and fat intake step by step affect people's Health, this also directly causes more and more people with various diseases, such as diabetes, cardiovascular disease, hypertension, height The a series of disease of blood lipid and gout etc., since a very long time, these diseases annoying always people, and people often need Disease is treated and prevented by the methods of keeping a diet and taking drugs, in these diseases it is the most dangerous both It is cardiovascular disease.
Heart is one of most important organ in human body, and major function is to provide power for blood flow, blood Operation is to body various pieces, and the heart of the mankind is located at lower section to the left, volume in the middle part of thoracic cavity and is approximately equivalent to a fist size, weight About 250 grams of amount, the heart of women is usually more small in size and light-weight than male, and the outer image peach of human heart is located at diaphragm On, to the left between two lungs, heart is made of cardiac muscle, four atrium sinistrum, left ventricle, atrium dextrum, right ventricle chamber compositions, wherein left Core indoor wall be it is most thick, this four chambers are body circulation respectively, the only way which must be passed of pulmonary circulation, between left atrium and left and right ventricles Between separated by interval, therefore it is not connected, have valve between atrium and ventricle, these valves flow into blood can only by atrium Ventricle, and cannot flow backwards, action of the heart is to push blood flow, sufficient blood flow is provided to organ, tissue, to supply oxygen With various nutriments and the final product of metabolism is taken away, cell is made to maintain normal metabolism and function, it is various endocrine in vivo They also will be transported to target cell by blood circulation, realize the Humoral immunity of body by hormone and some other humoral factors, Maintain the relative constant of organismic internal environment.In addition, the realization and the relative constant adjusting of body temperature of blood defence function, also all Blood is relied on constantly to circulate in the blood vessels, and the circulation of blood is the effect realization due to heart " pump ", heart Effect be it is huge, when myocardial contraction, push blood to enter artery, flow to whole body;When myocardial relaxation, blood flows back to the heart by vein It is dirty, so, heartthrob pushes the flowing of blood, is the working organ of blood transportation.
The appearance of cardiovascular disease easily causes to generate thrombus in angiocarpy, thrombus pole when running up to a certain amount of Easily cause blood vessel blockage, so as to cause cardiac insufficiency, serious the problem of will lead to cardiac arrest appearance is suffered from thus There are the people of cardiovascular disease to generally require to take thrombolytic agent for a long time to avoid accumulating appearance there is a situation where thrombus, however Traditional thrombolytic agent easily makes the organism metabolisms organ such as kidney after long-term use in the prevalence of biggish side effect At irreversible damage.
Summary of the invention
The present invention provides a kind of prevention and treatment cancer cells and the composition of cardiovascular disease and preparation method thereof, and having can be without pair The advantages of dissolution to thrombus of effect, solving traditional thrombolytic agent can cause damage to ask in organism metabolism organ Topic.
To achieve the above object, the invention provides the following technical scheme: a kind of group for preventing and treating cancer cell and cardiovascular disease Close object, including green onion, ginger and garlic extracting solution, lobelia chinensis, erigeron breviscapus, Radix Glycyrrhizae, selenium-rich garlic, traditional Chinese medicine of the five flavours extracting solution, eclipta, the five tastes Son, ginkgo leaf and starch, the raw material in formula are respectively as follows: green onion, ginger and garlic extracting solution 15%-25%, erigeron breviscapus by weight ratio 2%-5%, Radix Glycyrrhizae 2%-4%, selenium-rich garlic 7%-10%, traditional Chinese medicine of the five flavours extracting solution 35%-41%, eclipta 3%-8%, the five tastes Sub- 2%-5%, ginkgo leaf 2%-5%, starch 16%-25%, lobelia chinensis 2%-4%;
The green onion, ginger and garlic extracting solution is prepared by green onion, ginger, garlic and edible ethanol, in the green onion, ginger and garlic extracting solution Green onion, ginger, garlic and edible ethanol are respectively green onion 15%-25%, ginger 8%-18%, garlic 5%-15%, edible ethanol by weight ratio Green onion, ginger and garlic are added after edible ethanol extracts 60-90 days and are filtered to the residue of green onion, ginger and garlic, filter by 37%-72% Residue afterwards takes out spare;
Water is added in the residue of the green onion, ginger, garlic and starch mixes, the residue of water and starch and green onion, ginger, garlic presses weight Amount proportion be water 40%-55%, starch 3%-5%, green onion, ginger, garlic residue 40%-45%, by solution resulting after mixing into The boiling that 80 degrees Celsius of row high temperature, until its internal moisture content is reduced to 10% hereinafter, 1-2 hour a length of, steaming when boiling Solution after boiling is in colloid, and then completes the preparation of green onion, ginger and garlic extracting solution, to obtain green onion, ginger and garlic extracting solution;
The traditional Chinese medicine of the five flavours extracting solution is prepared by pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol, institute State the pueraria lobata in traditional Chinese medicine of the five flavours extracting solution, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol is respectively Radix Notoginseng by weight ratio 25%-29%, Radix Salviae Miltiorrhizae 15%-18%, fleece-flower root 8%-12%, pueraria lobata 5%-10%, safflower 1%-3%, edible ethanol 40%- 60%, pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol addition edible ethanol are stirred, it will after the completion of stirring After solution extracts 60-90 days, in solution pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root residue be filtered, after filtering Pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root residue take out it is spare;
By the residue of the pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root be incorporated as 2-6 times of residue weight pure water and For 0.05 times of starch of residue weight, thus to the residue of pure water, starch and pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root into Row boiling, boiling temperature are 100 degrees Celsius of constant temperature, continue boiling 1-3 hour, up to pure water, starch and pueraria lobata, Radix Notoginseng, red The solution that the residue boiling of flower, Radix Salviae Miltiorrhizae and the fleece-flower root goes out is in colloid, and then is filtered to colloid solution, filtered molten Liquid carries out purification processes, obtains traditional Chinese medicine of the five flavours extracting solution.
Preferably, the edible ethanol carries out 30-60 days constant temperature by a definite date using cereal such as wheat, rice, corn and sorghums 50 degrees Celsius of fermentation is filtered the residue of cereal after fermentation, to take its solution, is filtered to solution, until molten Particulate matter in liquid completely eliminates, and purifies to solution, and edible ethanol is obtained after purification.
Preferably, the starch uses cornstarch, and the Radix Glycyrrhizae is wet in 50 degrees Celsius of air of constant temperature using fresh Radix Glycyrrhizae Degree is the drying that 5-10 hours by a definite date are carried out in 10% space, crushes after the completion of drying to Radix Glycyrrhizae, makes the shape of Radix Glycyrrhizae Become diameter and be about the graininess of 1-3 mm in size, to be ground to licorice root particles, until the shape of Radix Glycyrrhizae becomes powder Shape completes the processing of Radix Glycyrrhizae.
Preferably, the ginger includes turmeric and ginger peel, and main component contains volatile oil, and the volatile oil contains turmerone 58%, 25% Cineole 0.9% of zingerene, sabinene 0.6%, borneol 0.5%, curcumin 0.3%.
The preparation method of the composition the following steps are included:
(1): by green onion, ginger and garlic extracting solution, lobelia chinensis, erigeron breviscapus, Radix Glycyrrhizae, selenium-rich garlic, traditional Chinese medicine of the five flavours extracting solution, eclipta, Schisandra chinensis, ginkgo leaf and starch are proportionally matched, matching method are as follows: and 20 parts of green onion, ginger and garlic extracting solution, erigeron breviscapus 3.5 Part, 3 parts of Radix Glycyrrhizae, 8.5 parts of selenium-rich garlic, 38 parts of traditional Chinese medicine of the five flavours extracting solution, 5 parts of eclipta, 3.5 parts of Schisandra chinensis, 3.5 parts of ginkgo leaf, 18.5 parts of starch are mixed.
(2): steam heating being carried out to mixture after the completion of mixing, heating environment is 100 degrees Celsius of relative temperature, relatively wet Degree 90%, when heating, are 90 minutes a length of, thus make vapor can easily by each material in mixture carry out uniformly plus It is wet, to adequately be sterilized mixture by moist vapor, mixture is cooled down after the completion of heating, to mixed Plastotype is carried out to mixture when the temperature of conjunction object is reduced to 50 degrees Celsius.
(3): mixture being subjected to stripping and slicing processing, mixture is subjected to plastotype, the shape of mixture after stripping and slicing post-processing Fashion into graininess or sheet, and then the mixture after plastotype dried, drying after the completion of obtain prevention and treatment cancer cell and The composition of cardiovascular disease, and then complete the preparation of thrombus composition.
Compared with prior art, it is provided by the invention it is a kind of prevent and treat cancer cell and cardiovascular disease composition, have with It is lower the utility model has the advantages that
1, the composition of the prevention and treatment cancer cell and cardiovascular disease passes through green onion, ginger and garlic extracting solution, traditional Chinese medicine of the five flavours extracting solution It is used cooperatively, makes composition in implementation process on the spot, since human body can generate free radicals this during metabolism Kind of harmful substance, it can cause cell chain reaction include thrombus formation, however there are also a kind of special substances in ginger It can prevent free radical from playing the role of anti-aging to the infringement of human body, and then avoid the problem that cardiovascula arteriosclerosis occurs, and raw The maintenance blood vessel elasticity of the cholesterol level in blood can drop in contained special object in ginger, be diluted to blood, and then avoid blood Liquid generates thrombus since cholesterol is excessively high, and by the setting of green onion and garlic, the sulphur compound contained in garlic has strength antithrombotic Activity can reduce cholesterol, effectively prevention diabetes, its bulb of green onion contains volatile oil, and main component is diallyl sulphur in oil Ether, dimension B2, ties up A, niacin, fat oil and mucilaginous substance at dimension B1, palmitinic acid, stearic acid, arachidic acid, oleic acid, sub- oil in fat oil Acid contains polysaccharide, cellulose, pectin in mucus juice, and pharmacological action is essentially identical with garlic, to keep green onion, ginger and garlic extracting solution right The effect from basic place's prevention and treatment is played in the formation of thrombus, and the pueraria lobata in traditional Chinese medicine of the five flavours extracting solution can make the increasing of coronary vasodilator blood flow Add, vascular resistence reduce, pueraria lobata play the role of obviously be depressured and it is hypoglycemic, Radix Notoginseng is significantly increased the work of coronary blood flow With safflower plays the role of expanding heart coronary artery, hypotensive activity, and can maintain the long period, and Radix Salviae Miltiorrhizae has promoting blood circulation and expansion The effect of blood vessel, the fleece-flower root have norcholesterol, anti arteriosclerosis effect, thus make traditional Chinese medicine of the five flavours extracting solution have blood pressure lowering, The effects of hypoglycemic, expansion stake blood vessel, increase vascular flow and activating microcirculation and removing stasis medicinal, so that traditional Chinese medicine of the five flavours extracting solution and green onion, ginger and garlic be made to extract Liquid uses simultaneously, allows user after taking this composition, can be in the common work of traditional Chinese medicine of the five flavours extracting solution and green onion, ginger and garlic extracting solution Thrombus is dissolved with lower, and thrombus is avoided to coagulate again, it, will not be to machine since this mixture is Chinese herbal medicine formula The metabolic organ of body causes to damage, so that this composition be made to have the advantages of dissolving to thrombus without side-effects, solves Traditional thrombolytic agent can cause the problem of damage to organism metabolism organ.
2, the composition of the prevention and treatment cancer cell and cardiovascular disease passes through lobelia chinensis, erigeron breviscapus, Radix Glycyrrhizae, selenium-rich garlic, ink Non-irrigated lotus, Schisandra chinensis, ginkgo leaf and starch are used cooperatively, and make this composition during use on the spot, by starch come pair These raw materials are condensed, to make raw material that can easily condense into composition, and then are stimulated by lobelia chinensis heart, Reinforce the convergent force of heart, cooperation erigeron breviscapus has anticoagulant feature, makes blood flow more smoothly, to make this The effect of the antithrombotic of composition is more preferable;
By the antiinflammation of eclipta, makes the myocardial infections as caused by thrombus that can easily obtain medical treatment, pass through Hypo acid in Radix Glycyrrhizae inhibits the reductase in liver, so that the blood viscosity for generating liver is greatly reduced, and then makes blood It can easily be flowed in the blood vessel of human body, so that making the ingredient of eclipta can easily be absorbed by body, and then make cardiac muscle The treatment speed of infection gets a promotion;
The characteristics of by Schisandra chinensis anti-liver injury, liver can be improved, and then liver function is made to get a promotion, make liver Dirty hematopoiesis quality is improved, and the viscosity for making liver generate blood further decreases, and dilutes blood further, into one The condensation for avoiding blood of step, eliminates one of issuable factor of thrombus again;
Treatment by ginkgo leaf to cardiac muscle is improved the vigor of cardiac muscle, obtains heart to the conveying function of blood To raising, and then the flow velocity of blood is improved, avoids the condensation of thrombus.
3, this composition in the actual implementation process, passes through lobelia chinensis, erigeron breviscapus, Radix Glycyrrhizae, selenium-rich garlic, eclipta, five Taste, ginkgo leaf and starch are used cooperatively, and allow user after taking this composition, heart obtains the conveying function of blood Hematopoiesis function to raising, liver gets a promotion, and reduces the viscosity of blood, is improved the dilatancy of blood vessel, into And the multiple necessary conditions for generating thrombus are removed on body, dispel thrombus can easily, can avoid that thrombus occurs Condensation, make the dissolution enhanced convenience of thrombus, and further protection body internal organs, this composition can be without side-effects to thrombus The cardiovascular disease of generation is treated and is prevented and treated, and more safe ready is used.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described, Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all Belong to the scope of protection of the invention.
The present invention provides a kind of compositions for preventing and treating cancer cell and cardiovascular disease, including green onion, ginger and garlic extracting solution, one side of something Lotus, erigeron breviscapus, Radix Glycyrrhizae, selenium-rich garlic, traditional Chinese medicine of the five flavours extracting solution, eclipta, Schisandra chinensis, ginkgo leaf and starch, the original in formula Material is respectively as follows: green onion, ginger and garlic extracting solution 15%-25% by weight ratio, and green onion, ginger and garlic extracting solution is by green onion, ginger, garlic and edible ethanol system Standby to form, ginger includes turmeric and ginger peel, and main component contains volatile oil, and volatile oil contains turmerone 58%, zingerene 25% Cineole 0.9%, sabinene 0.6%, borneol 0.5%, curcumin 0.3%, green onion, ginger, garlic in green onion, ginger and garlic extracting solution and edible Ethyl alcohol is respectively as follows: green onion 15%-25%, ginger 8%-18%, garlic 5%-15%, edible ethanol 37%-72% by weight ratio, will Green onion, ginger and garlic are added after edible ethanol extracts 60-90 days and are filtered to the residue of green onion, ginger and garlic, and filtered residue takes out Spare, erigeron breviscapus 2%-5%, Radix Glycyrrhizae 2%-4% inhibit the reductase in liver by the hypo acid in Radix Glycyrrhizae, to make liver The blood viscosity of dirty generation is greatly reduced, and flow blood can easily in the blood vessel of human body, selenium-rich garlic 7%-10%, and five Taste Chinese medicine extract 35%-41%, traditional Chinese medicine of the five flavours extracting solution are by pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol It is prepared, the pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol in traditional Chinese medicine of the five flavours extracting solution are distinguished by weight ratio For Radix Notoginseng 25%-29%, Radix Salviae Miltiorrhizae 15%-18%, fleece-flower root 8%-12%, pueraria lobata 5%-10%, safflower 1%-3%, edible second Pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol addition edible ethanol are stirred, have stirred by alcohol 40%-60% After solution is extracted 60-90 days after, in solution pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root residue be filtered, Filtered pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root residue take out spare, edible ethanol uses wheat, rice, corn 50 degrees Celsius of constant temperature of fermentation in 30-60 days by a definite date is carried out with cereal such as sorghums, the residue of cereal is filtered after fermentation, thus Its solution is taken, solution is filtered, until the particulate matter in solution completely eliminates, solution is purified, is obtained after purification Edible ethanol, the method includes the steps of:
(1): by the residue of pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root be incorporated as 2-6 times of residue weight pure water and For 0.05 times of starch of residue weight, thus to the residue of pure water, starch and pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root into Row boiling, boiling temperature are 100 degrees Celsius of constant temperature, continue boiling 1-3 hour, up to pure water, starch and pueraria lobata, Radix Notoginseng, red The solution that the residue boiling of flower, Radix Salviae Miltiorrhizae and the fleece-flower root goes out is in colloid, and then is filtered to colloid solution, filtered molten Liquid carries out purification processes, to obtain traditional Chinese medicine of the five flavours extracting solution.
(2): water is added in the residue of green onion, ginger, garlic and starch mixes, the residue of water and starch and green onion, ginger, garlic presses weight Amount proportion be water 40%-55%, starch 3%-5%, green onion, ginger, garlic residue 40%-45%, by solution resulting after mixing into The boiling that 80 degrees Celsius of row high temperature, until its internal moisture content is reduced to 10% hereinafter, 1-2 hour a length of, steaming when boiling Solution after boiling is in colloid, and then completes the preparation of green onion, ginger and garlic extracting solution, obtains green onion, ginger and garlic extracting solution, composition is in practical reality During applying, since human body can generate free radicals this harmful substance during metabolism, it can cause the company of cell Lock reactor includes the formation of thrombus, however there are also a kind of special substance, it can prevent infringement of the free radical to human body in ginger, Play the role of anti-aging, and then avoids the problem that cardiovascula arteriosclerosis occurs, and special object contained in ginger can drop in blood Cholesterol level maintain blood vessel elasticity, blood is diluted, avoids blood from generating thrombus since cholesterol is excessively high, passes through The setting of green onion and garlic, the sulphur compound contained in garlic have strength antithrombotic acitivity, can reduce cholesterol, effectively prevention glycosuria Disease, its bulb of green onion contain volatile oil, and main component is allyl sulfide, dimension B1, dimension B2, dimension A, niacin, fat oil and viscous in oil Liquid matter, palmitinic acid, stearic acid, arachidic acid, oleic acid, linoleic acid in fat oil contain polysaccharide, cellulose, pectin, medicine in mucus juice Reason effect it is essentially identical with garlic, make green onion, ginger and garlic extracting solution is formationed of thrombus can be played from all from prevention and treatment effect, the five tastes Pueraria lobata in Chinese medicine extract can be such that coronary vasodilator blood flow increases, and vascular resistence reduces, and pueraria lobata has obvious decompression and hypoglycemic Effect, Radix Notoginseng is significantly increased the effect of coronary blood flow, and safflower plays the role of expanding heart coronary artery, blood pressure lowering is made With, and the long period can be maintained, Radix Salviae Miltiorrhizae plays the role of promoting blood circulation and expansion blood vessel, and the fleece-flower root has norcholesterol, anti-artery hard Change effect makes traditional Chinese medicine of the five flavours extracting solution have blood pressure lowering, hypoglycemic, expansion stake blood vessel, increase the work such as vascular flow and activating microcirculation and removing stasis medicinal With, make traditional Chinese medicine of the five flavours extracting solution and green onion, ginger and garlic extracting solution while using, allows user after taking this composition, it can be in the five tastes Thrombus is dissolved under the collective effect of medicament extracting solution and green onion, ginger and garlic extracting solution, and thrombus is avoided to coagulate again, due to This mixture is Chinese herbal medicine formula, will not cause to damage to the metabolic organ of body, is made so that this composition be made to have without pair The advantages of dissolving to thrombus solves the problems, such as that traditional thrombolytic agent can cause damage to organism metabolism organ, Eclipta 3%-8%, the antiinflammation of eclipta make the myocardial infections as caused by thrombus that can easily obtain medical treatment, and lead to The reductase in the hypo acid inhibition liver in Radix Glycyrrhizae is crossed, the blood viscosity for generating liver is greatly reduced, and then makes blood can It is easily flowed in the blood vessel of human body, absorb the ingredient of eclipta can easily by body, make the treatment of myocardial infections Speed gets a promotion, Schisandra chinensis 2%-5%, the characteristics of by Schisandra chinensis anti-liver injury, can improve liver, and then make liver Dirty function gets a promotion, and is improved the hematopoiesis quality of liver, and the viscosity for making liver generate blood further decreases, and makes blood Liquid further dilutes, and further avoids the condensation of blood, eliminates one of issuable factor of thrombus again, ginkgo Leaf 2%-5%, the treatment by ginkgo leaf to cardiac muscle, is improved the vigor of cardiac muscle, makes heart to the conveying function of blood It is improved, improves the flow velocity of blood, avoid the condensation of thrombus, starch 16%-25%, starch uses cornstarch, Radix Glycyrrhizae Fresh Radix Glycyrrhizae is used, for the drying for carrying out 5-10 hours by a definite date in 10% space, to dry in 50 degrees Celsius of air humiditys of constant temperature Radix Glycyrrhizae is crushed at rear, so that the shape of Radix Glycyrrhizae is become the graininess that diameter is about 1-3 mm in size, thus to licorice root particles It is ground, until the shape of Radix Glycyrrhizae becomes powdered, to complete the processing of Radix Glycyrrhizae, the preparation method of composition includes following Step:
(1): by green onion, ginger and garlic extracting solution, lobelia chinensis, erigeron breviscapus, Radix Glycyrrhizae, selenium-rich garlic, traditional Chinese medicine of the five flavours extracting solution, eclipta, Schisandra chinensis, ginkgo leaf and starch are proportionally matched, matching method are as follows: and 20 parts of green onion, ginger and garlic extracting solution, erigeron breviscapus 3.5 Part, 3 parts of Radix Glycyrrhizae, 8.5 parts of selenium-rich garlic, 38 parts of traditional Chinese medicine of the five flavours extracting solution, 5 parts of eclipta, 3.5 parts of Schisandra chinensis, 3.5 parts of ginkgo leaf, 18.5 parts of starch are mixed.
(2): steam heating being carried out to mixture after the completion of mixing, heating environment is 100 degrees Celsius of relative temperature, relatively wet Degree 90%, when heating, are 90 minutes a length of, thus make vapor can easily by each material in mixture carry out uniformly plus It is wet, mixture is adequately sterilized by moist vapor, mixture is cooled down after the completion of heating, object to be mixed Temperature plastotype is carried out to mixture when being reduced to 50 degrees Celsius.
(3): mixture being subjected to stripping and slicing processing, mixture is subjected to plastotype, the shape of mixture after stripping and slicing post-processing Fashion into graininess or sheet, and then the mixture after plastotype dried, drying after the completion of obtain prevention and treatment cancer cell and The composition of cardiovascular disease completes the preparation of thrombus composition.
Lobelia chinensis 2%-4% stimulates heart by lobelia chinensis, reinforces the convergent force of heart, and cooperation oil lamp is thin It is pungent to have anticoagulant feature, make blood flow more smoothly, to keep the effect of the antithrombotic of this composition more preferable, uses For person after taking this composition, heart is improved the conveying function of blood, and the hematopoiesis function of liver gets a promotion, and drops The low viscosity of blood, is improved the dilatancy of blood vessel, and the multiple necessary conditions for generating thrombus obtain on body It removes, and then dispel thrombus can easily, so that this composition is can avoid that thrombus condensation occurs, keep the dissolution of thrombus more square Just, further protection body internal organs, make this composition can the cardiovascular disease without side-effects that thrombus is generated control It treats and prevents and treats, make the use more safe ready of this mixture.
When this composition is implemented on the spot, for user after taking this composition, heart obtains the conveying function of blood Hematopoiesis function to raising, liver gets a promotion, and reduces the viscosity of blood, is improved the dilatancy of blood vessel, into And the multiple necessary conditions for generating thrombus are removed on body, dispel thrombus can easily, it can using this composition It avoids that thrombus condensation occurs, makes the dissolution enhanced convenience of thrombus, further protection body internal organs, this composition can be without pairs The cardiovascular disease of effect generated to thrombus is treated and is prevented and treated, the use more safe ready of this mixture.
The following are section Example of the present invention, those skilled in the art can select according to the physical condition of different users Select different example schemes.
1 toxicity test of embodiment
One, acute toxicity test
1, experimental animal: level-one SD rat and NIH mouse.
2, test method: test method: large and small mouse acute toxicity test is according to horn method, if four agent of composition Amount group is respectively as follows: 2200,4500,12000 and 22200MG/KG.bw (drug is embodiment 2), every group of 10 animals, According to the disposably oral stomach-filling of 2% volume, its poisoning symptom, sign and death condition are observed after stomach-filling.
Test result: the acute toxicity tests are as follows:
Overview: after several minutes of stomach-filling tested material, a small number of rats of 22200mg/kgbw group and 12000mg/kgbw, The most rats of group and mouse occur that hind leg is out of strength, and Crawl gait is walked haltingly, and lie on one's side, the animal earliest death time be to tested material after 125 minutes, there is symptom, restored normal in 13 hours or so, Some Animals are poisoned to death.
Each group death and there is the symptom time as the result is shown in table.Therefore, it is looked into according to each group dead animal number GB15193.3-2003, the drug that embodiment 1 provides are all larger than 12000mg/ to the LD50 of female, male SD rat and NIH mouse kg·bw。
4, it is classified according to the acute toxicity of GB15193.3, embodiment 1,2,3 belongs to nontoxic grade.
Two, genetic toxicity test
1, Salmonella reversion test
1.1 test methods: the identified satisfactory salmonella typhimurium histidine defect TA97, TA98 of use, Tetra- plants of test strains of TA100, TA102 are carried out plus are tested with the dressing plate incorporation methods that rats'liver S9 is not added.
Test sets composition 0.8,4,20 and 100 4 dosage groups of μ l/ ware, tests every time while setting negative control group and sun Property control group, negative control group is distilled water, and positive controls are respectively TNFone, NaN3, MMC and 2-AF, each test agent Amount makees three parallel wares, repeats test twice.
1.2 test result;
Salmonella reversion test the result is as follows:
Note: numerical value is 3 plate mean values in table.
Upper table is as the result is shown: in addition to the TA102 bacterial strain for adding S9, average return of positive control ware becomes clump count and is all larger than feminine gender Twice of control;And average return of each dosage group of embodiment 2 becomes clump count within twice of negative control.
1.3 conclusions: embodiment 2 is negative in Salmonella reversion test.
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment Intrinsic element.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (5)

1. a kind of composition for preventing and treating cancer cell and cardiovascular disease, including it is green onion, ginger and garlic extracting solution, lobelia chinensis, erigeron breviscapus, sweet Grass, selenium-rich garlic, traditional Chinese medicine of the five flavours extracting solution, eclipta, Schisandra chinensis, ginkgo leaf and starch, it is characterised in that: the raw material in formula is pressed Weight proportion is respectively as follows: green onion, ginger and garlic extracting solution 15%-25%, erigeron breviscapus 2%-5%, Radix Glycyrrhizae 2%-4%, selenium-rich garlic 7%- 10%, traditional Chinese medicine of the five flavours extracting solution 35%-41%, eclipta 3%-8%, Schisandra chinensis 2%-5%, ginkgo leaf 2%-5%, starch 16%-25%, lobelia chinensis 2%-4%;
The green onion, ginger and garlic extracting solution is prepared by green onion, ginger, garlic and edible ethanol, green onion, ginger in the green onion, ginger and garlic extracting solution, Garlic and edible ethanol are respectively green onion 15%-25%, ginger 8%-18%, garlic 5%-15%, edible ethanol 37%- by weight ratio 72%, green onion, ginger and garlic are added after edible ethanol extracts 60-90 days, the residue of green onion, ginger and garlic is filtered, it is filtered residual Slag takes out spare;
Water is added in the residue of the green onion, ginger, garlic and starch mixes, the residue of water and starch and green onion, ginger, garlic is matched by weight Than for water 40%-55%, starch 3%-5%, green onion, ginger, garlic residue 40%-45%, solution resulting after mixing is carried out high 80 degrees Celsius of boiling of temperature, until its internal moisture content be reduced to 10% hereinafter, when boiling it is 1-2 hours a length of, after boiling Solution be in colloid, and then complete green onion, ginger and garlic extracting solution preparation, obtain green onion, ginger and garlic extracting solution;
The traditional Chinese medicine of the five flavours extracting solution is prepared by pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol, described five Pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol in taste Chinese medicine extract are respectively Radix Notoginseng by weight ratio 25%-29%, Radix Salviae Miltiorrhizae 15%-18%, fleece-flower root 8%-12%, pueraria lobata 5%-10%, safflower 1%-3%, edible ethanol 40%- 60%, pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae, the fleece-flower root and edible ethanol addition edible ethanol are stirred, it will after the completion of stirring After solution extracts 60-90 days, in solution pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root residue be filtered, after filtering Pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root residue take out it is spare;
The residue of the pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root is incorporated as 2-6 times of residue weight of pure water and to be residual The starch that 0.05 times of slag weight, to be steamed to the residue of pure water, starch and pueraria lobata, Radix Notoginseng, safflower, Radix Salviae Miltiorrhizae and the fleece-flower root It boils, boiling temperature is 100 degrees Celsius of constant temperature, continues boiling 1-3 hours, until pure water, starch and pueraria lobata, Radix Notoginseng, safflower, pellet The solution that the residue boiling of ginseng and the fleece-flower root goes out is in colloid, and then is filtered to colloid solution, filtered solution into Row purification processes obtain traditional Chinese medicine of the five flavours extracting solution.
2. a kind of composition for preventing and treating cancer cell and cardiovascular disease according to claim 1, it is characterised in that: the food 50 degrees Celsius of constant temperature of fermentation in 30-60 days by a definite date is carried out using cereal such as wheat, rice, corn and sorghums with ethyl alcohol, after fermentation The residue of cereal is filtered, to take its solution, and then solution is filtered, until the particulate matter in solution disappears completely It removes, to purify to solution, edible ethanol is obtained after purification.
3. a kind of composition for preventing and treating cancer cell and cardiovascular disease according to claim 1, it is characterised in that: the shallow lake Powder uses cornstarch, the Radix Glycyrrhizae use fresh Radix Glycyrrhizae 50 degrees Celsius of air humiditys of constant temperature for carry out in 10% space for The drying of phase 5-10 hour, crushes Radix Glycyrrhizae after the completion of drying, and so that the shape of Radix Glycyrrhizae is become diameter is about 1-3 mm in size Graininess until the shape of Radix Glycyrrhizae becomes powdered, complete the processing of Radix Glycyrrhizae to grind to licorice root particles.
4. a kind of composition for preventing and treating cancer cell and cardiovascular disease according to claim 1, it is characterised in that: the ginger Including turmeric and ginger peel, main component contains volatile oil, and the volatile oil contains turmerone 58%, 25% Cineole of zingerene 0.9%, sabinene 0.6%, borneol 0.5%, curcumin 0.3%.
5. the preparation method of a kind of prevention and treatment cancer cell according to claim 1 and the composition of cardiovascular disease, feature It is, comprising the following steps:
(1): by green onion, ginger and garlic extracting solution, lobelia chinensis, erigeron breviscapus, Radix Glycyrrhizae, selenium-rich garlic, traditional Chinese medicine of the five flavours extracting solution, eclipta, the five tastes Son, ginkgo leaf and starch are proportionally matched, matching method are as follows: 20 parts of green onion, ginger and garlic extracting solution, 3.5 parts of erigeron breviscapus, sweet 3 parts of grass, 8.5 parts of selenium-rich garlic, 38 parts of traditional Chinese medicine of the five flavours extracting solution, 5 parts of eclipta, 3.5 parts of Schisandra chinensis, 3.5 parts of ginkgo leaf, starch 18.5 parts are mixed;
(2): steam heating being carried out to mixture after the completion of mixing, heating environment is 100 degrees Celsius of relative temperature, relative humidity 90%, when heating, is 90 minutes a length of, thus humidify vapor easily each material in mixture can uniformly, Mixture is adequately sterilized by moist vapor, mixture is cooled down after the completion of heating, object to be mixed Plastotype is carried out to mixture when temperature is reduced to 50 degrees Celsius;
(3): mixture being subjected to stripping and slicing processing, mixture is subjected to plastotype after stripping and slicing post-processing, the shape of mixture is moulded It is dried at graininess or sheet, and then to the mixture after plastotype, prevention and treatment cancer cell and painstaking effort is obtained after the completion of drying The composition of pipe disease completes the preparation of thrombus composition.
CN201910108166.8A 2019-02-02 2019-02-02 A kind of prevention and treatment cancer cell and the composition of cardiovascular disease and preparation method thereof Pending CN109675006A (en)

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CN1208648A (en) * 1998-08-17 1999-02-24 王景胜 Chinese herb medicine allicin health-care liquid
CN102580024A (en) * 2012-02-22 2012-07-18 王景胜 Composition for treating cardiovascular diseases

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