CN109663062A - A kind of selenium-rich peptide dendrobium nutrient alkali and its boiling method, application - Google Patents
A kind of selenium-rich peptide dendrobium nutrient alkali and its boiling method, application Download PDFInfo
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- CN109663062A CN109663062A CN201910098767.5A CN201910098767A CN109663062A CN 109663062 A CN109663062 A CN 109663062A CN 201910098767 A CN201910098767 A CN 201910098767A CN 109663062 A CN109663062 A CN 109663062A
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- dendrobium
- selenium
- liquid
- dendrobium nobile
- peptide
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- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 title claims abstract description 50
- 229910052711 selenium Inorganic materials 0.000 title claims abstract description 50
- 239000011669 selenium Substances 0.000 title claims abstract description 50
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 40
- 241001523681 Dendrobium Species 0.000 title claims abstract description 19
- 235000015097 nutrients Nutrition 0.000 title claims abstract description 18
- 239000003513 alkali Substances 0.000 title claims abstract description 13
- 238000009835 boiling Methods 0.000 title claims abstract description 12
- 238000000034 method Methods 0.000 title claims abstract description 10
- 240000004638 Dendrobium nobile Species 0.000 claims abstract description 46
- 239000007788 liquid Substances 0.000 claims abstract description 38
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 25
- 241001474374 Blennius Species 0.000 claims abstract description 22
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000008280 blood Substances 0.000 claims abstract description 11
- 210000004369 blood Anatomy 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000003814 drug Substances 0.000 claims abstract description 7
- 201000005569 Gout Diseases 0.000 claims abstract description 6
- 230000000694 effects Effects 0.000 claims abstract description 6
- 210000003734 kidney Anatomy 0.000 claims abstract description 5
- 230000004060 metabolic process Effects 0.000 claims abstract description 5
- 210000002700 urine Anatomy 0.000 claims abstract description 4
- 229940079593 drug Drugs 0.000 claims abstract description 3
- 229930013930 alkaloid Natural products 0.000 claims description 11
- 150000003797 alkaloid derivatives Chemical class 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 claims description 7
- 229940116269 uric acid Drugs 0.000 claims description 7
- RYAHJFGVOCZDEI-UFFNCVEVSA-N Dendrobine Chemical compound C([C@H]1CC[C@@H]2[C@@]31C)N(C)[C@@H]3[C@H]1[C@@H](C(C)C)[C@@H]2C(=O)O1 RYAHJFGVOCZDEI-UFFNCVEVSA-N 0.000 claims description 3
- 239000002585 base Substances 0.000 claims description 3
- RYAHJFGVOCZDEI-CZKZLRAZSA-N dendrobine Natural products O=C1O[C@@H]2[C@H](C(C)C)[C@H]1[C@H]1[C@@]3(C)[C@@H]2N(C)C[C@H]3CC1 RYAHJFGVOCZDEI-CZKZLRAZSA-N 0.000 claims description 3
- 238000006386 neutralization reaction Methods 0.000 claims description 3
- 230000003064 anti-oxidating effect Effects 0.000 claims description 2
- 239000013078 crystal Substances 0.000 claims description 2
- 238000004090 dissolution Methods 0.000 claims description 2
- 230000002503 metabolic effect Effects 0.000 claims description 2
- 230000007102 metabolic function Effects 0.000 claims description 2
- 230000006825 purine synthesis Effects 0.000 claims description 2
- 239000003053 toxin Substances 0.000 claims description 2
- 231100000765 toxin Toxicity 0.000 claims description 2
- 210000001835 viscera Anatomy 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000004575 stone Substances 0.000 claims 1
- 238000009776 industrial production Methods 0.000 abstract description 2
- 241000195493 Cryptophyta Species 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 241000026010 Dendrobium candidum Species 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 241000282452 Ailuropoda melanoleuca Species 0.000 description 1
- 241000512259 Ascophyllum nodosum Species 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 241001646834 Mesona Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000011651 chromium Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- 230000029553 photosynthesis Effects 0.000 description 1
- 238000010672 photosynthesis Methods 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention belongs to biologies and new medical technology field, are related to a kind of selenium-rich peptide dendrobium nutrient alkali and its boiling method, application.The dendrobium nutrient alkali, including dendrobium nobile liquid, seaweed organic selenium and ox bone peptide；Dendrobium nobile liquid is made of water and dendrobium nobile, ratio 8-300:1；Dendrobium nobile liquid: seaweed organic selenium: ox bone peptide=1:0.0008-0.0016:0.002-0.004.Simple process is boiled, it is easily operated, it is low in cost, to environment without any pollution, it is suitble to large-scale industrial production.The dendrobium nutrient alkali can be used for making gout drug and health care product, can reduce metabolism lithate to the burden of kidney, can effectively allow tophus to return to blood and be discharged by urine, and is without any side effects.
Description
Technical field
The invention belongs to biology and new medical technology field, be related to a kind of selenium-rich peptide dendrobium nutrient alkali and its boiling method,
Using.The dendrobium nobile alkaloid is a kind of completely new plant alkaloid, is treating gout disease in conjunction with seaweed organic selenium, ox bone peptide
Medical value in disease.
Technical background
Dendrobium nobile is a kind of rare Chinese medicine, is herbaceos perennial, and stem is grown thickly, cylindrical type, 10-30 centimetres high, slightly
3-8 millimeters, civil, it is known as " giant panda " of " help mesona " medicine circle.Since fresh dendrobium nobile should not save, fresh medicine is due to it
How fresh and tender juice is, is easy to rot, especially intermittent drizzles in the rainy season season, less easy to maintain, therefore in most of shops of Chinese medicines and hospital's Chinese medicine
Fresh class medicinal material is rarely provided in room.Dendrobium nobile is divided into dendrobium candidum, Dendrobium Moniliforme, water plant dendrobium nobile, purple dendrobium, gold in type again
Hairpin dendrobium nobile etc.: dendrobium nobile rich in more than the ten kinds of alkaloids such as polysaccharide, amino acid and dendrobine, dendrobium nobile amine base, rich in calcium, potassium, sodium, magnesium,
Several Ten microelements such as zinc, iron, manganese, selenium, copper, chromium, nickel, germanium.
" seaweed " is the general name of the marine algaes such as kelp, seaweed, thallus laminariae, agar, is submarine algae, is
The cryptogam of plant kingdom, algae include the biology that several inhomogeneities generate energy with photosynthesis.Selenium is needed by human micro-
Mineral nutrient is measured, there is inorganic and organic two kinds of chemical forms；Plant can be more effectively by nothing in the ecological chain of selenium
Machine selenium is converted into organic selenium, and the biological value of Selenium in Plants is higher relative to animal selenium.It is demonstrated experimentally that vegetable active selenium is inhaled by human body
Yield is 20 times of inorganic selenium.Seaweed is rich in a large amount of organic selenium, is natural organic selenium carrier and human body food organic selenium
Main source.
Ox bone peptide is the high-quality activity extracted in ox bone, and bone collagen peptide, average weight is in 800 dalton, ox bone
Peptide is the extremely easy micromolecular collagen peptide being absorbed by the body.
Patent content
The present invention provides a kind of selenium-rich peptide dendrobium nutrient alkali and its boiling methods, application, and method is simple, the dendrobium nobile of preparation
Alkaloid has medical value in gout treatment.
The technical solution adopted by the invention is as follows:
A kind of selenium-rich peptide dendrobium nutrient alkali, including dendrobium nobile liquid, seaweed organic selenium and ox bone peptide；Dendrobium nobile liquid is by water and dendrobium nobile group
At ratio 8-300:1；Dendrobium nobile liquid: seaweed organic selenium: ox bone peptide=1:0.0008-0.0016:0.002-0.004.
Above-mentioned selenium-rich peptide dendrobium nutrient alkali, boiling method are as follows:
(1) 4-8 kg of water is poured into tanning container, 300-500 grams of dendrobium nobile is added；Dendrobium nobile liquid is heated to 80-100
DEG C, then control 60-80 DEG C tanning 1-2 hours, repeatedly boil 2-4 times, the dendrobium nobile liquid after being boiled；
(2) the dendrobium nobile liquid after boiling several times is poured into container, makes the content of alkaloid in 0.3 to 1.6 gram/L, is dropped to temperature
To 30-60 DEG C or so, 20-40 gs/kg of micro- g/kg of seaweed organic selenium 800-1600 and ox bone peptide is added in filter and remove residue.
(3) after standing 4-6 hours, seaweed organic selenium and ox bone peptide are completely dissolved in dendrobium nobile liquid, then stir 5- with stirring rod
10 minutes to get arrive selenium-rich peptide dendrobium nutrient liquid.
Tanning simple process of the invention, it is easily operated, it is not necessarily to special installation, it is low in cost, to environment without any pollution,
It is suitble to large-scale industrial production.
Dendrobium nutrient alkali of the invention can be used for making gout drug and health care product.Ox bone peptide has carrier and rapidly enters
The effect of blood, seaweed organic selenium have toxin expelling, metabolism and antioxidation, and there is dendrobine neutralization uric acid and dissolution to have become
The solid-state tophus of type acts on.Ox bone peptide can carry alkaloid and organic selenium rapidly enters blood, neutralize uric acid, acid-base neutralization
Afterwards, tophus will soften, and form liquid, urate crystal will be precipitated from joint, internal organs in the state of low uric acid level
It returns in blood, when the uric acid carried in blood is the state of liquid, the metabolic capability of kidney will enhance, and add organic selenium
Metabolic function, inhibit purine synthesis, alleviate metabolism lithate to the burden of kidney, can effectively allow tophus return to blood by
Urine discharge, and it is without any side effects.
Specific embodiment
Embodiment 1
(1) 4 kg of water are poured into tanning container, 300 grams of dendrobium nobiles is added；Dendrobium nobile liquid is heated to 90 DEG C, is then controlled
70 DEG C tanning 1-2 hours, repeatedly boil 2-4 times, the dendrobium nobile liquid after being boiled；
(2) the dendrobium nobile liquid after boiling several times is poured into container, makes the content of alkaloid in 0.8 gram/L, is down to 45 to temperature
DEG C or so, filter and remove residue is added 1000 micro- gs/kg and 30 gs/kg of ox bone peptide of seaweed organic selenium.
(3) after standing 5 hours, seaweed organic selenium and ox bone peptide are completely dissolved in dendrobium nobile liquid, then stir 8 points with stirring rod
Clock to get arrive selenium-rich peptide dendrobium nutrient liquid.
Embodiment 2
(1) 6 kg of water are poured into tanning container, 400 grams of dendrobium nobiles is added；Dendrobium nobile liquid is heated to 95 DEG C, is then controlled
75 degree tanning 1-2 hours, repeatedly boil 2-4 times, the dendrobium nobile liquid after being boiled；
(2) the dendrobium nobile liquid after boiling several times is poured into container, makes the content of alkaloid in 1.0 grams/L, is down to 50 to temperature
Degree left and right, filter and remove residue are added 1300 micro- gs/kg and 35 gs/kg of ox bone peptide of seaweed organic selenium.
(3) after standing 6 hours, seaweed organic selenium and ox bone peptide are completely dissolved in dendrobium nobile liquid, then stir 9 points with stirring rod
Clock to get arrive selenium-rich peptide dendrobium nutrient liquid.
Embodiment 3
(1) 7 kg of water are poured into tanning container, 350 grams of dendrobium nobiles is added；Dendrobium nobile liquid is heated to 85 DEG C, is then controlled
It boils 2 hours, boils 2-4 times repeatedly, the dendrobium nobile liquid after being boiled at 65 DEG C；
(2) the dendrobium nobile liquid after boiling several times is poured into container, makes the content of alkaloid in 1.5 grams/L, is down to 35 to temperature
DEG C or so, filter and remove residue is added 1500 micro- gs/kg and 36 gs/kg of ox bone peptide of seaweed organic selenium.
(3) after standing 4 hours, seaweed organic selenium and ox bone peptide are completely dissolved in dendrobium nobile liquid, then stir 9 points with stirring rod
Clock to get arrive selenium-rich peptide dendrobium nutrient liquid.
Claims (3)
1. a kind of selenium-rich peptide dendrobium nutrient alkali, which is characterized in that including dendrobium nobile liquid, seaweed organic selenium and ox bone peptide；Dendrobium nobile liquid by
Water and dendrobium nobile composition, ratio 8-300:1；Dendrobium nobile liquid: seaweed organic selenium: ox bone peptide=1:0.0008-0.0016:0.002-
0.004。
2. a kind of boiling method of selenium-rich peptide dendrobium nutrient alkali described in claim 1, it is characterised in that following steps:
(1) 4-8 kg of water is poured into tanning container, 300-500 grams of dendrobium nobile is added；Dendrobium nobile liquid is heated to 80-100 DEG C, so
After control 60-80 DEG C tanning 1-2 hours, repeatedly boil 2-4 times, the dendrobium nobile liquid after being boiled；
(2) the dendrobium nobile liquid after boiling several times is poured into container, makes the content of alkaloid in 0.3 to 1.6 gram/L, is down to temperature
30-60 DEG C or so, 20-40 gs/kg of micro- g/kg of seaweed organic selenium 800-1600 and ox bone peptide is added in filter and remove residue；
(3) after standing 4-6 hours, seaweed organic selenium and ox bone peptide are completely dissolved in dendrobium nobile liquid, then are divided with stirring rod stirring 5-10
Clock to get arrive selenium-rich peptide dendrobium nutrient liquid.
3. a kind of selenium-rich peptide dendrobium nutrient alkali described in claim 1 treats gout drug and health care product for making；Ox bone peptide, which has, to be carried
Body and the effect for rapidly entering blood, seaweed organic selenium have toxin expelling, metabolism and antioxidation, and dendrobine, which has, neutralizes urine
Acid, and the solid-state tophus effect that dissolution is molded；Ox bone peptide can carry alkaloid and organic selenium rapidly enters blood, neutralize
Uric acid, after acid-base neutralization, tophus will soften, and form liquid, will analyse from joint, internal organs in the state of low uric acid level
Urate crystal returns in blood out, and when the uric acid carried in blood is the state of liquid, the metabolic capability of kidney will enhance,
Along with the metabolic function of organic selenium, inhibit purine synthesis, alleviate metabolism lithate to the burden of kidney, can effectively allow gout
Stone returns to blood and is discharged by urine.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811077773 | 2018-09-16 | ||
| CN2018110777734 | 2018-09-16 |
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| Publication Number | Publication Date |
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| CN109663062A true CN109663062A (en) | 2019-04-23 |
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| CN201910098767.5A Withdrawn CN109663062A (en) | 2018-09-16 | 2019-01-31 | A kind of selenium-rich peptide dendrobium nutrient alkali and its boiling method, application |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104740335A (en) * | 2013-12-30 | 2015-07-01 | 浙江中医药大学 | Dendrobium officinale leaf extract with uric acid reducing function and application of dendrobium officinale leaf extract |
| US20160009604A1 (en) * | 2013-02-27 | 2016-01-14 | Chao Xie | High-energy composite peptide selenoprotein nutrient solution, preparation method and application thereof |
-
2019
- 2019-01-31 CN CN201910098767.5A patent/CN109663062A/en not_active Withdrawn
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160009604A1 (en) * | 2013-02-27 | 2016-01-14 | Chao Xie | High-energy composite peptide selenoprotein nutrient solution, preparation method and application thereof |
| CN104740335A (en) * | 2013-12-30 | 2015-07-01 | 浙江中医药大学 | Dendrobium officinale leaf extract with uric acid reducing function and application of dendrobium officinale leaf extract |
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Application publication date: 20190423 |