CN109662904A - It is a kind of to have effects that the skin care compositions of whitening antioxidation and its application and preparation method - Google Patents
It is a kind of to have effects that the skin care compositions of whitening antioxidation and its application and preparation method Download PDFInfo
- Publication number
- CN109662904A CN109662904A CN201910115193.8A CN201910115193A CN109662904A CN 109662904 A CN109662904 A CN 109662904A CN 201910115193 A CN201910115193 A CN 201910115193A CN 109662904 A CN109662904 A CN 109662904A
- Authority
- CN
- China
- Prior art keywords
- weight
- parts
- extract
- acid
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9722—Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9733—Lichens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9741—Pteridophyta [ferns]
- A61K8/9749—Filicopsida or Pteridopsida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
Have effects that the composition of whitening antioxidation and its application and preparation method the present invention relates to a kind of.The composition by weight, including contains water fugacity 0.1-3.0 parts by weight；It polymerize antiallergic factor 0.01-0.5 parts by weight；Gotu Kola P.E 0.1-1.0 parts by weight；Niacinamide 0.1-3.0 parts by weight；Alpha-arbutin 0.01-0.3 parts by weight；Tranexamic acid 0.1-3.0 parts by weight；Camomile extract 0.01-0.1 parts by weight；Ellagic acid 0.1-1.0 parts by weight；Plant whitening extracting solution 0.1-3.0 parts by weight；Acetyl chitosamine 0.1-0.5 parts by weight；Hydrolyzed yeast albumen 1.0-5.0 parts by weight；Glycosaminoglycan 0.1-3.0 parts by weight；Extract solution from aloe 0.01-0.1 parts by weight；Green algal extract 0.1-3.0 parts by weight；- 2 0.1-1.0 parts by weight of hexapeptide；Sodium Hyaluronate 0.01-0.5 parts by weight etc..The present invention medical mechanism different using each ingredient, the synergistic function between each ingredient is given full play to, so that resulting composition can speed up cell metabolism, capture free radical, inhibits the peroxidating of lipid, melanocyte channel is blocked, accelerates melanin horn cell and falls off.
Description
Technical field
The present invention relates to daily chemical products technical field more particularly to it is a kind of have effects that the composition of whitening antioxidation and its
Using and preparation method.
Background technique
There are two the barrier actions of aspect for skin tool: on the one hand preventing internal water, the loss of electrolyte and other substances；
On the other hand the intrusion for preventing extraneous harmful substance, remains in the stabilization of human internal environment, is physiologically playing important guarantor
Protective function, while skin also assists in the metabolic process of human body.As the saying goes " one white hide hundred ugly ", from ancient times to the present Chinese to whitening all
Lie in very much, whitening is also a kind of maintenance to skin, and skin-whitening is even more the emphasis of women skin care throughout the year, the whitening of face
It is particularly important.
Skin is black, depends primarily on the ability of individual melanocyte synthesis of melanin in vivo.It is thin in the basal layer of epidermis of people
Intercellular is dispersed with melanocyte, and the tyrosine Enzyme that it contains can be by oxidizing tyrosine at polysaccharide, and centre is using a series of
Metabolic process, can finally generate melanin.Melanin production it is more, skin is more black；Conversely, skin is more fair.
Present beauty parlor mostly uses injecting type whitening needle to carry out whitening, but injecting type whitening needle is at high cost, fresh-keeping
Phase is short, need to frequently inject maintenance effect；And injecting type whitening needle formula is not fixed, containing solidifying in the formula of many medical institutions
Blood agent ingredient, leads to inject the whitening needle hidden danger that contains thrombus or cerebral infarction, and modern medicine believes that, injecting type treatment side
One mode of case, inherently increase hidden danger is not recommended to use in non-essential medical therapy scheme, because being easy
Cause the side effects such as nagiopasthyrosis and drug resistance.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of skin care item, can not only accelerate cell metabolism, capture certainly
By the peroxidating of base, inhibition lipid, also has and block melanocyte channel, quickening melanin horn cell falls off and other effects.
The present invention adopts the following technical scheme that realization.A kind of skin care compositions, including component as follows by weight:
Skin conditioning agent 10-20 parts by weight；
Moisturizer 10-20 parts by weight.
In the present invention, the skin conditioning agent be selected from contain water fugacity, polymerization the antiallergic factor, Gotu Kola P.E, niacinamide,
Alpha-arbutin, Trenaxmine, tremella polysaccharides, camomile extract, ellagic acid, plant whitening extracting solution, acetyl chitosamine, hydrolysis ferment
It is female albumen, glycosaminoglycan, extract solution from aloe, green algal extract, 3-o- ethylascorbyl, a kind of or several in hexapeptide -2
Kind；It more preferably include above-mentioned whole components；
Wherein, dosage is respectively to contain water fugacity 0.1-3.0 parts by weight, polymerization antiallergic to above-mentioned each component in the composition
Factor 0.01-0.5 parts by weight, Gotu Kola P.E 0.1-1.0 parts by weight, niacinamide 0.1-3.0 parts by weight, alpha-arbutin
0.01-0.3 parts by weight, tranexamic acid 0.1-3.0 parts by weight, tremella polysaccharides 0.01-0.1 parts by weight, camomile extract 0.01-
0.1 parts by weight, ellagic acid 0.1-1.0 parts by weight, plant whitening extracting solution 0.1-3.0 parts by weight, acetyl chitosamine 0.1-0.5 weight
Measure part, hydrolyzed yeast albumen 1.0-5.0 parts by weight, glycosaminoglycan 0.1-3.0 parts by weight, extract solution from aloe 0.01-0.1 weight
Measure part, green algal extract 0.1-3.0 parts by weight, 3-o- ethylascorbyl 0.1-3.0 parts by weight, -2 0.1-1.0 weight of hexapeptide
Part.
The moisturizer is one or more of in Sodium Hyaluronate, glycine betaine, erythrite, methyl propanediol, glycerol；More
Preferably include above-mentioned whole components；
Wherein, dosage is respectively Sodium Hyaluronate 0.01-0.5 parts by weight, beet to above-mentioned each component in the composition
Alkali 0.1-1.0 parts by weight, erythrite 1.0-5.0, methyl propanediol 1.0-10.0 parts by weight, glycerol 1.0-10.0 parts by weight.
The culvert water fugacity is selected from one of European shield-fern root extract, Iceland's lichens extract, mud coal extract
Or it is several；
The polymerization antiallergic factor is selected from Cer NP, phytosphingosine, caprylic/capric triglyceride, cholesterine, hydrogen
Change one or more of lecithin, stearic acid, oleic acid, lactic acid；
The plant whitening extracting solution is selected from glycyrrhiza glabra root extract, Artemisia capillaris flower extract, mulberry root extract, jujube fruit
One or more of extract, radix scutellariae root extract.
European shield-fern root extract is the alcohol extract or water extract of European shield-fern.European shield-fern (Dryopteris
It filix-mas is) Dryopteridaceae, a kind of plant under Dryopteris.The Xinjiang northwestward and the north are originated in, Europe, north are distributed in
Beauty, the Central Asia, north temperate zone.The complex chemical composition of pteridophyte, being distributed the most universal has phenols and triterpene compound.Binary
Phenols has antibacterial, hemostasis, cough-relieving and other effects.
Iceland's lichens extract is the alcohol extract or water extract of Iceland's lichens, Iceland's lichens (CETRARIA ISLANDICA)
Extract shows that the extract can slow down elastin laminin to the inhibition of elastoser and to the facilitation of collagen generation
The degradation of fiber promotes the growth of collagen fabric, can maintain skin elasticity, is used for anti-wrinkle cosmetic；Extract is still used
Make antibacterial agent, anti-inflammatory agent and smelly dose of suppression.
Mud coal extract, mud coal are also known as turf or peat, are that higher plant residuum passes through life in immersion and anaerobic environment
The effects of object, chemistry, by decomposing incomplete plant residue, the loose organic substance accumulation of the compositions such as humus and minerals
Object, how brown, dark brown.Mud coal is that be grown in a kind of bad layer in ancient stratum early raw for coal, is under neritic environment by algae
The sapropelic coal that the unicellular lower eukaryotes such as class, mushroom are formed.Mud coal has rich in multiple beneficials components such as protein, humic acid, minerals
Good water physics, physical-chemical, biological characteristics make it agriculturally also have been widely used.
Tremella polysaccharides (Tremellam) are a kind of acid heteroglycans, from tremella (Tremella fuciformisBerk)
Obtained in entity, backbone structure is by the mannosan of α-(1 → 3) glucosides key connection, and branch is by glucuronic acid and wood
Sugar composition.For Basidiomycetes polysaccharide para-immunity reinforcing agent, has the function of improving body's immunity and promote leucocyte.It can be significant
The phagocytic function for improving experimental animal reticuloendothelial cell has and promotes nospecific immunity effect, improves immunoglobulin, serum
The level of total complement.It can prevent and treat as radiation and bone marrow suppression caused by anti-tumor drug (such as CTX), can also promote liver
The synthesis of internal protein.
Gotu Kola P.E is the alcohol extract or water extract of centella.Centella (Centella asiatica (L.)
It Urban), is Umbelliferae perennial herb, stem is crawled, and it is elongated, it takes root on section.It is distributed in the more provinces and regions of China.Pharmacology shows product
Snow grass has compact epidermis and corium coupling part, skin can be made to limber up, and helps to solve cutis laxa phenomenon, makes skin light
Cunning is flexible；Help promotes collagen in skin corium to be formed, and regenerates fibrin, and reconnect is got up, and fundamentally disappears
Except mother's line, achieve the effect that skin compact smooth.Impaired organization healing and consolidation skin can also be helped.
Camomile extract is the alcohol extract or water extract of flower.Chamomile is compositae plant, originates in Europe.Chamomile it is other
Title is called Rome chamomile, German chamomile.With good Shu Min, maintenance sensitivity skin, reduce thin red capillary, reduction hair
Red, the effects of adjustment colour of skin is uneven, but in terms of current and not all chamomile can be used for beauty.Chamomile is living rich in flavonoids
Property ingredient, the ingredient have anti-oxidant, antiangiogenic, anti-inflammatory, anti-allergy and antiviral effect.
Glycyrrhiza glabra root extract is the alcohol extract or water extract of glycyrrhiza glabra root.Glycyrrhiza glabra (Glycyrrhiza
Glabra L.) also known as licorice (North SinKiang) perennial herb, root is sturdy with rhizomes, diameter 0.5-3cm, root skin brown, the inside
Yellow has sweet taste.Glycyrrhiza glabra extract can go deep into inside skin and keep high activity, effectively during inhibition melanin production
The activity of a variety of enzymes (as inhibited tyrosinase) is that one kind fast, efficient, safe, green sun-proof, whitening cosmetics add
Add agent.Glycyrrhiza glabra extract also has effects that prevent pachylosis and anti-inflammatory, antibacterial simultaneously.
Artemisia capillaris flower extract is the alcohol extract or water extract of Artemisia capillaris flower.Artemisia capillaris (ARTEMISIA CAPILLARIS)
Nickname Artemisia capillaris (Amplification on Materia Medica), pharmacology aspect, for the main component for controlling liver, gallbladder illness.Also contain volatile oil, main component has
Family β-pinane child, Herba Artemisiae Scopariae dienone (capillione), oriental wormwood stagnant (capillene) and capillarin (capillarin) etc..Gu Ben
Rapid style of writing such as Shennong's Herbal and Compendium of Material Medica etc. are recorded: main rheumatism, fever and chills, perverse trend heat knot, jaundice etc..Aqueous extract is to more
Kind bacillus, coccus have inhibiting effect, and volatile oil has antimycotic effect.
Mulberry root extract is the water extract or alcohol extract of mulberry root.Sang Gen, Chinese medicine name.For moraceae plants mulberry Morus alba
L. root.It is distributed in all parts of the country.It calms the frightened with heat-clearing, the effect of dispelling wind and removing obstruction in the meridians.It is usually used in frightened epilepsy, hot eyes, toothache, muscles and bones pain
Bitterly.The ethyl alcohol and acetone leachate of Mulberry Roots play the role of inhibiting fungi in vitro.
Radix scutellariae root extract is the alcohol extract or water extract of scutellariae,radix.Radix scutellariae (Scutellaria baicalensis
Georgi), alias Radix Scutellariae, tsuchikane tea root are lamiaceae labiatae scutellaria herbaceos perennials；Pharmacology shows that radix scutellariae has
The root of radix scutellariae is used as medicine, bitter, cold in nature, there is heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention and other effects.Cure mainly warm heat disease, upper breathing
The diseases such as road infection, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis, hot eyes, threatened abortion, hypertension, carbuncle swells furuncle sore.It is yellow
The clinical antibiotic property of a kind of reed mentioned in ancient books is better than the coptis, and does not develop drug resistance.
Aloe barbadensis Miller leaf juice is the natural extract of aloe juice, and aloe barbadensis Miller (Aloe vera L.) is A Fuhua
The perennial evergreen succulent plant of section's Aloe, originates in Africa.Wherein containing there are many moisturizing ingredient beneficial to human body and battalion
It forms point.Scientific research thinks that swashs due to containing glucose, mannose, uronic acid, calcium, hydrated protein enzyme, biology in aloe
Element, hormone, protein, amino acid, vitamin, minerals and other microelements, thus have nourishing and moisturizing, it is sun-proof,
Anti-inflammatory, hair-dressing and hair care and other effects；Meanwhile it to softening skin, convergence, prevent and treat acne, prevent pachylosis, anti-inflammatory anti-itch, shield
Hair keeps skin is delicate white clean etc. to have remarkable efficacy.
Green algal extract is the alcohol extract or water extract of green alga.Green alga (CHLOROPHYTA SPP.) is alkalescent, contains
Balanced various nutritions are enriched, protein, lipid, polysaccharide, dietary fiber, vitamin A, B, C, D, E, micro member are rich in
Element, minerals, folic acid, chlorophyll and preciousness biologically active element.In addition, also containing a kind of most important composition in green alga: green
Algae promotes growth factor (CGF), it, which has, induces interferon, exciting human defence, the macrophage in immuning tissue, T cell
With the effect of B cell, and can promote to the removing toxic substances of harmful substance, the Excretion for polluting environment using dioxin as representative.
As the preferred technical solution of the present invention, a kind of composition is provided, composed of the following components:
Contain water fugacity 0.1-3.0 parts by weight；It polymerize antiallergic factor 0.01-0.5 parts by weight；Gotu Kola P.E 0.1-1.0
Parts by weight；Niacinamide 0.1-3.0 parts by weight；Alpha-arbutin 0.01-0.3 parts by weight；Tranexamic acid 0.1-3.0 parts by weight；Tremella is more
Sugared 0.01-0.1 parts by weight；Camomile extract 0.01-0.1 parts by weight；Ellagic acid 0.1-1.0 parts by weight；Plant whitening extracts
Liquid 0.1-3.0 parts by weight；Acetyl chitosamine 0.1-0.5 parts by weight；Hydrolyzed yeast albumen 1.0-5.0 parts by weight；Glucose amino is poly-
Sugared 0.1-3.0 parts by weight；Extract solution from aloe 0.01-0.1 parts by weight；Green algal extract 0.1-3.0 parts by weight；3-o- ethyl is anti-bad
Hematic acid 0.1-3.0 parts by weight；- 2 0.1-1.0 parts by weight of hexapeptide；Sodium Hyaluronate 0.01-0.5 parts by weight；Glycine betaine 0.1-1.0
Parts by weight；Erythrite 1.0-5.0；Methyl propanediol 1.0-10.0 parts by weight；Glycerol 1.0-10.0 parts by weight.
Composition described in any of the above-described technical solution provided by the present invention all has good whitening, oxidation resistant
Effect.
It is an unexpected discovery of the invention that adding the function that the whole in above-mentioned raw materials is remarkably improved composition in the composition
Effect.
The present invention also provides compositions described in an any of the above-described technical solution to have whitening, oxidation resistant shield in preparation
Application in skin product.Wherein the skin care item include facial mask, face cream, essence, toner, lotion, gel, condensation.
The skin care item are using above-mentioned any one technical solution resulting composition as active component.
Specifically, the present invention provides a kind of essence, the component including following parts by weight:
Active component: contain water fugacity 0.1-3.0 parts by weight；It polymerize antiallergic factor 0.01-0.5 parts by weight；Centella is extracted
Object 0.1-1.0 parts by weight；Niacinamide 0.1-3.0 parts by weight；Alpha-arbutin 0.01-0.3 parts by weight；Tranexamic acid 0.1-3.0 weight
Part；Tremella polysaccharides 0.01-0.1 parts by weight；Camomile extract 0.01-0.1 parts by weight；Ellagic acid 0.1-1.0 parts by weight；Plant
Whitening extracting solution 0.1-3.0 parts by weight；Acetyl chitosamine 0.1-0.5 parts by weight；Hydrolyzed yeast albumen 1.0-5.0 parts by weight；Portugal
Sugared aminoglycan 0.1-3.0 parts by weight；Extract solution from aloe 0.01-0.1 parts by weight；Green algal extract 0.1-3.0 parts by weight；3-o-
Ethylascorbyl 0.1-3.0 parts by weight；- 2 0.1-1.0 parts by weight of hexapeptide；Sodium Hyaluronate 0.01-0.5 parts by weight；Beet
Alkali 0.1-1.0 parts by weight；Erythrite 1.0-5.0；Methyl propanediol 1.0-10.0 parts by weight；Glycerol 1.0-10.0 parts by weight；Increase
Thick dose of 0.1-1.0 parts by weight；Chelating agent 0.01-0.1 parts by weight；PH regulator 0.01-0.1 parts by weight；No added preservative；
0.01-0.5 parts by weight；Solvent supplies 100 parts by weight.
The thickener is selected from card wave U2O；The chelating agent is selected from EDETATE SODIUM；The PH regulator is selected from hydroxide
Sodium；The no added preservative is one or more of sweet selected from tropolone, decoyl hydroximic acid, ethylhexyl, preferably
Including above-mentioned whole components；The solvent is selected from deionized water.
As the preferred technical solution of the present invention, a kind of essence is provided, total weight parts are 100 parts, by following components group
At: contain water fugacity 0.1-3.0 parts by weight；It polymerize antiallergic factor 0.01-0.5 parts by weight；Gotu Kola P.E 0.1-1.0 weight
Part；Niacinamide 0.1-3.0 parts by weight；Alpha-arbutin 0.01-0.3 parts by weight；Tranexamic acid 0.1-3.0 parts by weight；Tremella polysaccharides
0.01-0.1 parts by weight；Camomile extract 0.01-0.1 parts by weight；Ellagic acid 0.1-1.0 parts by weight；Plant whitening extracting solution
0.1-3.0 parts by weight；Acetyl chitosamine 0.1-0.5 parts by weight；Hydrolyzed yeast albumen 1.0-5.0 parts by weight；Glycosaminoglycan
0.1-3.0 parts by weight；Extract solution from aloe 0.01-0.1 parts by weight；Green algal extract 0.1-3.0 parts by weight；3-o- ethyl Vitamin C
Sour 0.1-3.0 parts by weight；- 2 0.1-1.0 parts by weight of hexapeptide；Sodium Hyaluronate 0.01-0.5 parts by weight；Glycine betaine 0.1-1.0 weight
Measure part；Erythrite 1.0-5.0；Methyl propanediol 1.0-10.0 parts by weight；Glycerol 1.0-10.0 parts by weight；Card wave U2O 0.1-
1.0 parts by weight；EDETATE SODIUM 0.01-0.1 parts by weight；Sodium hydroxide 0.01-0.1 parts by weight；Decoyl hydroximic acid；0.01-0.5 weight
Measure part；Deionized water supplies 100 parts by weight.
Essence provided by the present invention can substantially speed up cell metabolism, capture free radical, inhibit the mistake of lipid
Oxidation blocks melanocyte channel, accelerates melanin horn cell and falls off, and safeguards skin water content, promotes that skin corium is micro- to follow
Ring makes skin net white penetrating.
The present invention also provides a kind of preparation methods of above-mentioned essence, comprising: above-mentioned active component (composition) is mixed,
Essence is made.
The preparation method of the essence is specific as follows:
A, raw material card wave U2O is sprinkled into the configuration pot for holding raw material deionized water and EDETATE SODIUM, under complete wetting
30Hz is stirred and is heated；Configuration pot is added in pre-dispersed methyl propanediol, Sodium Hyaluronate to continue to stir, is heated to 80 DEG C；
B, raw materials glycerine, glycine betaine, erythrite are sequentially added 30Hz in configuration pot to be stirred until homogeneous, then starts to drop
Temperature；
C, be cooled to 50 DEG C by raw material sodium hydroxide be configured to 10% solution be added to configuration pot 30Hz be stirred until homogeneous, continue
Cooling；
D, 45 DEG C are cooled to by raw material Gotu Kola P.E, niacinamide, alpha-arbutin, tranexamic acid, ellagic acid, acetyl chitose
Amine, 3-o- ethylascorbyl be sequentially added configuration pot in 30Hz be stirred until homogeneous, then will contain water fugacity, polymerization antiallergic because
Son, tremella polysaccharides, camomile extract, plant whitening extracting solution, hydrolyzed yeast albumen are added to 30Hz in configuration pot and stir to equal
It is even；
E, after being cooled to 45 DEG C by the no added preservative of raw material, glycosaminoglycan, extract solution from aloe, green algal extract,
Hexapeptide -2 is added to configuration pot 30Hz and is stirred until homogeneous；Feeding detects, and 80 mesh filter-cloth filterings discharge after qualification, and essence is made.
Technical solution of the present invention has the following beneficial effects:
The present invention medical mechanism different using each ingredient, gives full play to the synergistic function between each ingredient, so that institute
The composition obtained can speed up cell metabolism, capture free radical, inhibits the peroxidating of lipid, blocks melanocyte channel,
Accelerate melanin horn cell to fall off.It safeguards skin water content, promotes skin corium microcirculation, make skin net white penetrating.
Specific embodiment
The embodiments given below are intended to further illustrate the invention.
Embodiment 1-3 and comparative example 1-3 provide a kind of composition respectively, by weight；
It is formulated such as table 1:
The preparation method of essence obtained by embodiment 1-3:
A, raw material card wave U2O is sprinkled into the configuration pot for holding raw material deionized water and EDETATE SODIUM, under complete wetting
30Hz is stirred and is heated；Configuration pot is added in pre-dispersed methyl propanediol, Sodium Hyaluronate to continue to stir, is heated to 80 DEG C；
B, raw materials glycerine, glycine betaine, erythrite are sequentially added 30Hz in configuration pot to be stirred until homogeneous, then starts to drop
Temperature；
C, be cooled to 50 DEG C by raw material sodium hydroxide be configured to 10% solution be added to configuration pot 30Hz be stirred until homogeneous, continue
Cooling；
D, 45 DEG C are cooled to resist raw material niacinamide, alpha-arbutin, tranexamic acid, ellagic acid, acetyl chitosamine, 3-o- ethyl
Bad hematic acid is sequentially added 30Hz in configuration pot and is stirred until homogeneous, and then extracts tremella polysaccharides, camomile extract, plant whitening
Liquid, hydrolyzed yeast albumen are added to 30Hz in configuration pot and are stirred until homogeneous；
E, after being cooled to 45 DEG C by the no added preservative of raw material, glycosaminoglycan, extract solution from aloe, green algal extract,
Hexapeptide -2 is added to configuration pot 30Hz and is stirred until homogeneous；Feeding detects, and 80 mesh filter-cloth filterings discharge after qualification, and essence is made.
1 whitening antioxidation essence of comparative example and preparation method
Preparation method:
A, raw material card wave U2O is sprinkled into the configuration pot for holding raw material deionized water and EDETATE SODIUM, under complete wetting
30Hz is stirred and is heated；Configuration pot is added in pre-dispersed methyl propanediol, Sodium Hyaluronate to continue to stir, is heated to 80 DEG C；
B, raw materials glycerine, glycine betaine, erythrite are sequentially added 30Hz in configuration pot to be stirred until homogeneous, then starts to drop
Temperature；
C, be cooled to 50 DEG C by raw material sodium hydroxide be configured to 10% solution be added to configuration pot 30Hz be stirred until homogeneous, continue
Cooling；
D, be cooled to 45 DEG C raw material Gotu Kola P.E, tranexamic acid, ellagic acid, acetyl chitosamine, 3-o- ethyl is anti-bad
Hematic acid is sequentially added 30Hz in configuration pot and is stirred until homogeneous, then that culvert water fugacity, the polymerization antiallergic factor, tremella polysaccharides, ocean is sweet
Chrysanthemum extract, plant whitening extracting solution, hydrolyzed yeast albumen are added to 30Hz in configuration pot and are stirred until homogeneous；
E, after being cooled to 45 DEG C by the no added preservative of raw material, glycosaminoglycan, extract solution from aloe, green algal extract,
Hexapeptide -2 is added to configuration pot 30Hz and is stirred until homogeneous；Feeding detects, and 80 mesh filter-cloth filterings discharge after qualification, and essence is made.
2 whitening antioxidation essence of comparative example and preparation method
A, raw material card wave U2O is sprinkled into the configuration pot for holding raw material deionized water and EDETATE SODIUM, under complete wetting
30Hz is stirred and is heated；Configuration pot is added in pre-dispersed methyl propanediol, Sodium Hyaluronate to continue to stir, is heated to 80 DEG C；
B, raw materials glycerine, glycine betaine, erythrite are sequentially added 30Hz in configuration pot to be stirred until homogeneous, then starts to drop
Temperature；
C, be cooled to 50 DEG C by raw material sodium hydroxide be configured to 10% solution be added to configuration pot 30Hz be stirred until homogeneous, continue
Cooling；
D, it is cooled to 45 DEG C raw material niacinamide, alpha-arbutin, 3-o- ethylascorbyl are sequentially added in configuration pot
30Hz is stirred until homogeneous, and hydrolyzed yeast albumen is then added to 30Hz in configuration pot and is stirred until homogeneous；
E, after being cooled to 45 DEG C by the no added preservative of raw material, glycosaminoglycan, extract solution from aloe, green algal extract,
Hexapeptide -2 is added to configuration pot 30Hz and is stirred until homogeneous；Feeding detects, and 80 mesh filter-cloth filterings discharge after qualification, and essence is made.
3 whitening antioxidation essence of comparative example and preparation method
A, raw material card wave U2O is sprinkled into the configuration pot for holding raw material deionized water and EDETATE SODIUM, under complete wetting
30Hz is stirred and is heated；Configuration pot is added in pre-dispersed methyl propanediol, Sodium Hyaluronate to continue to stir, is heated to 80 DEG C；
B, raw materials glycerine, glycine betaine, erythrite are sequentially added 30Hz in configuration pot to be stirred until homogeneous, then starts to drop
Temperature；
C, be cooled to 50 DEG C by raw material sodium hydroxide be configured to 10% solution be added to configuration pot 30Hz be stirred until homogeneous, continue
Cooling；
D, 45 DEG C are cooled to resist raw material niacinamide, alpha-arbutin, tranexamic acid, ellagic acid, acetyl chitosamine, 3-o- ethyl
Bad hematic acid is sequentially added 30Hz in configuration pot and is stirred until homogeneous, and then extracts tremella polysaccharides, camomile extract, plant whitening
Liquid is added to 30Hz in configuration pot and is stirred until homogeneous；
E, the no added preservative of raw material, hexapeptide -2 configuration pot 30Hz is added to after being cooled to 45 DEG C to be stirred until homogeneous；It takes
Material detects, and 80 mesh filter-cloth filterings discharge after qualification, and essence is made.
White-skinned face function tests (T/ZHCA 001-2018)
Reagent and material: use for laboratory water, using the tertiary effluent in GB/T6682；In embodiment 1-3 and comparative example 1-3
Essence；Chipless water-absorbing dry paper handkerchief.
Test equipment
Tristimulus values colorimeter；Assay balance, precision 0.0001g.
Test condition:
20 DEG C -22 DEG C of environment temperature, relative humidity 40-60% of test, and carry out real-time dynamic monitoring；
The test conditions such as tester, place, instrument in test process are consistent.
Test method
Number of subjects is 30 people, and test position is forearm area side, and every time before test, subject uniformly cleans tested portion
Position, and blotted with chipless water-absorbing dry paper handkerchief.
It is required that product is smeared uniformly；The left and right arm of random arrangement is tested area, and subject applies once in each daily morning and evening,
Service life is 5 weeks.Within test period, recipient site does not use other any cosmetics.
Test result is shown in Table 2.
By table 2 as it can be seen that recipient site is using after sample, sample test value was compared with initial value, the 0th week experimental period
Into the 5th week time range, TA ° of skin I value was in raising trend.Wherein, the test group of embodiment 1-3, the difference of ITA ° of value
In significant difference, the difference difference of ITA ° of group of comparative example 1-3 value is unobvious, therefore the whitening effect of the test group of embodiment 1-3
Fruit is apparently higher than the test group of comparative example 1-3.Wherein 2 effect of embodiment is better than embodiment 1 and embodiment 2.
Anti-oxidant test:
Antioxidant activity is indicated with scavenging ability of DPPH free radical size.Example 1-3 and comparative example 1-3 institute respectively
The essence 2g obtained is added to 2.0ml containing 2 × 10-4The DPPH ethanol solution of mmol/l, and mix well, room temperature is protected from light
After standing 20min, using solvent as blank control, absorbance value 1 is surveyed at 517nm；Every group is done 3 repetitions, is averaged, institute's total
According to as shown in table 3.
Table 3.
As shown in table 3, essence obtained by embodiment 1-3 is apparently higher than comparative example 1-3 institute to the clearance rate of DPPH free radical
Essence is obtained to the clearance rate of DPPH free radical, wherein the clearance rate highest of embodiment 2, therefore the anti-oxidation efficacy of embodiment 2
More preferably.
Specific embodiments of the present invention are described in detail above, but it is merely an example, the present invention is simultaneously unlimited
It is formed on particular embodiments described above.To those skilled in the art, any couple of present invention carries out equivalent modifications and
Substitution is also all among scope of the invention.Therefore, without departing from the spirit and scope of the invention made by equal transformation and
Modification, all should be contained within the scope of the invention.
Claims (10)
1. a kind of composition, which is characterized in that by weight, comprising:
Skin conditioning agent 10-20 parts by weight；
Moisturizer 10-20 parts by weight.
2. composition according to claim 1, which is characterized in that skin conditioning agent be selected from contain water fugacity, polymerization antiallergic because
Son, Gotu Kola P.E, niacinamide, alpha-arbutin, Trenaxmine, tremella polysaccharides, camomile extract, ellagic acid, plant whitening
Extracting solution, acetyl chitosamine, hydrolyzed yeast albumen, glycosaminoglycan, extract solution from aloe, green algal extract, 3-o- ethyl are anti-
It is one or more of in bad hematic acid, hexapeptide -2；
Moisturizer is one or more of in Sodium Hyaluronate, glycine betaine, erythrite, methyl propanediol, glycerol.
3. composition according to claim 2, which is characterized in that
Skin conditioning agent include contain water fugacity, polymerization the antiallergic factor, Gotu Kola P.E, niacinamide, alpha-arbutin, Trenaxmine,
Tremella polysaccharides, camomile extract, ellagic acid, plant whitening extracting solution, acetyl chitosamine, hydrolyzed yeast albumen, glucose amino
Glycan, extract solution from aloe, green algal extract, 3-o- ethylascorbyl and hexapeptide -2；
Moisturizer includes Sodium Hyaluronate, glycine betaine, erythrite, methyl propanediol and glycerol.
4. composition according to claim 3, which is characterized in that
The skin conditioning agent constituent content includes containing water fugacity 0.1-3.0 parts by weight；It polymerize antiallergic factor 0.01-0.5 weight
Part；Gotu Kola P.E 0.1-1.0 parts by weight；Niacinamide 0.1-3.0 parts by weight；Alpha-arbutin 0.01-0.3 parts by weight；Blood coagulation
Sour 0.1-3.0 parts by weight；Tremella polysaccharides 0.01-0.1 parts by weight；Camomile extract 0.01-0.1 parts by weight；Ellagic acid 0.1-
1.0 parts by weight；Plant whitening extracting solution 0.1-3.0 parts by weight；Acetyl chitosamine 0.1-0.5 parts by weight；Hydrolyzed yeast albumen
1.0-5.0 parts by weight；Glycosaminoglycan 0.1-3.0 parts by weight；Extract solution from aloe 0.01-0.1 parts by weight；Green algal extract
0.1-3.0 parts by weight；3-o- ethylascorbyl 0.1-3.0 parts by weight；Hexapeptide -20.1-1.0 parts by weight；
The moisturizer constituent content includes Sodium Hyaluronate 0.01-0.5 parts by weight；Glycine betaine 0.1-1.0 parts by weight；Erythrite
1.0-5.0；Methyl propanediol 1.0-10.0 parts by weight；Glycerol 1.0-10.0 parts by weight.
5. according to the described in any item compositions of claim 2-4, which is characterized in that
The culvert water fugacity is selected from one of European shield-fern root extract, Iceland's lichens extract, mud coal extract or several
Kind；
The polymerization antiallergic factor is selected from Cer NP, phytosphingosine, caprylic/capric triglyceride, cholesterine, hydrogenation ovum
One or more of phosphatide, stearic acid, oleic acid, lactic acid；
The plant whitening extracting solution is selected from glycyrrhiza glabra root extract, Artemisia capillaris flower extract, mulberry root extract, jujube fruit and extracts
One or more of object, radix scutellariae root extract.
6. the described in any item compositions of claim 1-5 have in preparation accelerates cell metabolism, block melanocyte logical
Road, accelerate melanocyte fall off effect skin care item in application；
Preferably, the skin care item include facial mask, face cream, essence, toner, lotion, gel, condensation.
7. a kind of essence, which is characterized in that including composition as described in any one in claim 1-5 as active constituent.
8. essence according to claim 7, which is characterized in that the essence further include:
9. essence according to claim 8, which is characterized in that
Thickener is selected from card wave U2O；
Chelating agent is selected from EDETATE SODIUM；
PH regulator is selected from sodium hydroxide；
No added preservative is one or more of sweet selected from tropolone, decoyl hydroximic acid, ethylhexyl；Solvent is selected from
Deionized water.
10. a kind of method for preparing the described in any item essences of claim 7-9, which comprises the steps of:
A, raw material card wave U2O is sprinkled into the configuration pot for holding raw material deionized water and EDETATE SODIUM, to 30Hz under complete wetting
It stirs and heats；Configuration pot is added in pre-dispersed methyl propanediol, Sodium Hyaluronate to continue to stir, is heated to 80 DEG C；
B, raw materials glycerine, glycine betaine, erythrite are sequentially added 30Hz in configuration pot to be stirred until homogeneous, then starts to cool down；
C, be cooled to 50 DEG C by raw material sodium hydroxide be configured to 10% solution be added to configuration pot 30Hz be stirred until homogeneous, continue to drop
Temperature；
D, be cooled to 45 DEG C by raw material Gotu Kola P.E, niacinamide, alpha-arbutin, tranexamic acid, ellagic acid, acetyl chitosamine,
3-o- ethylascorbyl is sequentially added 30Hz in configuration pot and is stirred until homogeneous, then by moisturizing agent, polymerization the antiallergic factor, tremella
Polysaccharide, camomile extract, plant whitening extracting solution, yeast brilliant white essence are added to 30Hz in configuration pot and are stirred until homogeneous；
E, by the no added preservative of raw material, glycosaminoglycan, extract solution from aloe, green algal extract, hexapeptide-after being cooled to 45 DEG C
2, which are added to configuration pot 30Hz, is stirred until homogeneous；Feeding detects, and 80 mesh filter-cloth filterings discharge after qualification.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910115193.8A CN109662904A (en) | 2019-02-14 | 2019-02-14 | It is a kind of to have effects that the skin care compositions of whitening antioxidation and its application and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910115193.8A CN109662904A (en) | 2019-02-14 | 2019-02-14 | It is a kind of to have effects that the skin care compositions of whitening antioxidation and its application and preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109662904A true CN109662904A (en) | 2019-04-23 |
Family
ID=66151988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910115193.8A Pending CN109662904A (en) | 2019-02-14 | 2019-02-14 | It is a kind of to have effects that the skin care compositions of whitening antioxidation and its application and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109662904A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110013450A (en) * | 2019-05-09 | 2019-07-16 | 伊犁弥玥泉生物科技有限公司 | A kind of the whitening and softening skin composition and preparation method of the hot spring containing mineral |
| CN110448494A (en) * | 2019-09-08 | 2019-11-15 | 葆姿(成都)健康管理有限公司 | A kind of skin care compositions and its application and preparation method with anti-ageing reparation effect |
| CN111214418A (en) * | 2020-03-13 | 2020-06-02 | 佛山市奥姿美生物科技有限公司 | Efficient barrier repair composition and application thereof |
| CN112168736A (en) * | 2020-10-15 | 2021-01-05 | 高颜苑科技(深圳)有限责任公司 | Whitening and freckle removing composition and preparation method thereof |
| CN115212134A (en) * | 2022-07-27 | 2022-10-21 | 哈尔滨敷尔佳科技股份有限公司 | Anti-aging nano composition, preparation method and application thereof |
| CN115317436A (en) * | 2022-10-14 | 2022-11-11 | 广州优理氏生物科技有限公司 | Composition with mild whitening and freckle removing effects and application thereof |
| CN115737477A (en) * | 2023-01-06 | 2023-03-07 | 广州美尔生物科技有限公司 | Whitening composition, whitening antiseptic composition and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784365A (en) * | 2014-01-08 | 2014-05-14 | 片仔癀（上海）生物科技研发有限公司 | Whitening cream and preparation method thereof |
| CN105708751A (en) * | 2016-01-19 | 2016-06-29 | 广州市美姿贺化妆品有限公司 | Senile-resistant skin care product and preparation method thereof |
| CN108618976A (en) * | 2018-07-11 | 2018-10-09 | 北京婼薇乐护肤品有限公司 | Subregion facial mask |
| CN109223588A (en) * | 2018-09-29 | 2019-01-18 | 安婕妤化妆品科技股份有限公司 | A kind of replenishing water and preserving moisture cosmetics |
-
2019
- 2019-02-14 CN CN201910115193.8A patent/CN109662904A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784365A (en) * | 2014-01-08 | 2014-05-14 | 片仔癀（上海）生物科技研发有限公司 | Whitening cream and preparation method thereof |
| CN105708751A (en) * | 2016-01-19 | 2016-06-29 | 广州市美姿贺化妆品有限公司 | Senile-resistant skin care product and preparation method thereof |
| CN108618976A (en) * | 2018-07-11 | 2018-10-09 | 北京婼薇乐护肤品有限公司 | Subregion facial mask |
| CN109223588A (en) * | 2018-09-29 | 2019-01-18 | 安婕妤化妆品科技股份有限公司 | A kind of replenishing water and preserving moisture cosmetics |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110013450A (en) * | 2019-05-09 | 2019-07-16 | 伊犁弥玥泉生物科技有限公司 | A kind of the whitening and softening skin composition and preparation method of the hot spring containing mineral |
| CN110013450B (en) * | 2019-05-09 | 2021-11-19 | 伊犁弥玥泉生物科技有限公司 | Whitening and skin-tendering composition containing mineral hot spring and preparation method thereof |
| CN110448494A (en) * | 2019-09-08 | 2019-11-15 | 葆姿(成都)健康管理有限公司 | A kind of skin care compositions and its application and preparation method with anti-ageing reparation effect |
| CN111214418A (en) * | 2020-03-13 | 2020-06-02 | 佛山市奥姿美生物科技有限公司 | Efficient barrier repair composition and application thereof |
| CN112168736A (en) * | 2020-10-15 | 2021-01-05 | 高颜苑科技(深圳)有限责任公司 | Whitening and freckle removing composition and preparation method thereof |
| CN115212134A (en) * | 2022-07-27 | 2022-10-21 | 哈尔滨敷尔佳科技股份有限公司 | Anti-aging nano composition, preparation method and application thereof |
| CN115317436A (en) * | 2022-10-14 | 2022-11-11 | 广州优理氏生物科技有限公司 | Composition with mild whitening and freckle removing effects and application thereof |
| CN115737477A (en) * | 2023-01-06 | 2023-03-07 | 广州美尔生物科技有限公司 | Whitening composition, whitening antiseptic composition and application thereof |
| CN115737477B (en) * | 2023-01-06 | 2023-04-07 | 广州美尔生物科技有限公司 | Whitening composition, whitening antiseptic composition and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109662904A (en) | It is a kind of to have effects that the skin care compositions of whitening antioxidation and its application and preparation method | |
| KR101059471B1 (en) | Cosmetic composition for skin aging | |
| CN109549917A (en) | It is a kind of to have effects that skin care compositions that antiallergic is releived and its application and preparation method | |
| CN109662928A (en) | A kind of skin care compositions and its application and preparation method with sun-proof reparation effect | |
| KR101266180B1 (en) | Vegetable antibacterial composition and cosmetic composition for improving skin using the same | |
| KR20100066694A (en) | Cosmetic composition containing moisturizing complex for moisturizing the skin | |
| CN113873997A (en) | A functional cosmetic composition containing plant extract as active component and its preparation method | |
| CN104784507A (en) | Traditional Chinese medicine composition with multiple cosmetic effects and application | |
| CN109223681A (en) | A kind of multiple-effect skin care compositions and the application in cosmetics | |
| KR101829892B1 (en) | A cosmetic composition comprising fraxinus rhynchophylla extract and calystegia soldanella extract | |
| KR101128564B1 (en) | The manufacturing process of lithospermum erythrorhizon soap controlled by vineger | |
| KR20160087113A (en) | Cosmetics containing flowers | |
| KR101816725B1 (en) | Manufacturing method for fermented extracts and cosmetic composition comprising fermented extracts | |
| KR100867514B1 (en) | How to manufacture a soap from lithospermum erythrorhizon | |
| CN108670933B (en) | Skin care composition with moisturizing, whitening and anti-aging functions and application thereof | |
| CN106727012A (en) | A kind of acne-eliminating cosmetic composition | |
| CN106728340A (en) | Chinese medicine composition with hair care effect and its preparation method and application | |
| KR102004366B1 (en) | A cosmetic composition comprising centipeda minima extract | |
| JPH0616530A (en) | Cosmetic | |
| KR101980887B1 (en) | A cosmetic composition comprising trichosanthes kirilowii extract and metaplexis japonica extract | |
| CN105998617A (en) | Externally applied traditional Chinese medicine extract with effect of soothing senile pruritus, as well as preparation method and application thereof | |
| KR101990387B1 (en) | Oriental cosmetic composition comprising the extract of coptis chinensis | |
| KR20110128384A (en) | The composition material and the manufacturing process for skin-wrinkle, moisture and skin-lightening uses by midam-kyungokko | |
| CN109381419A (en) | Cosmetic composition comprising silver-colored sweet-scented osmanthus extract and cognate clematis extract as effective component | |
| KR100750352B1 (en) | Skin whitening cosmetics composite containing oriental herb extract and manufacturing method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20190423 |
|
| WD01 | Invention patent application deemed withdrawn after publication |