CN109620597A - Simultaneously automatic control pneumatic and the low atmospheric pressure test device of oxygen content can be set - Google Patents
Simultaneously automatic control pneumatic and the low atmospheric pressure test device of oxygen content can be set Download PDFInfo
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- CN109620597A CN109620597A CN201811429178.2A CN201811429178A CN109620597A CN 109620597 A CN109620597 A CN 109620597A CN 201811429178 A CN201811429178 A CN 201811429178A CN 109620597 A CN109620597 A CN 109620597A
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 174
- 239000001301 oxygen Substances 0.000 title claims abstract description 174
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 174
- 238000012360 testing method Methods 0.000 title claims abstract description 16
- 239000007789 gas Substances 0.000 claims abstract description 43
- 238000005086 pumping Methods 0.000 claims abstract description 38
- 238000012937 correction Methods 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 8
- 238000004364 calculation method Methods 0.000 claims description 7
- 230000008569 process Effects 0.000 claims description 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 1
- 229910001882 dioxygen Inorganic materials 0.000 claims 1
- 238000002474 experimental method Methods 0.000 abstract description 16
- 238000010586 diagram Methods 0.000 description 7
- 230000008859 change Effects 0.000 description 6
- 230000006378 damage Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000000153 supplemental effect Effects 0.000 description 4
- 206010021143 Hypoxia Diseases 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 238000009423 ventilation Methods 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 239000004519 grease Substances 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000255 pathogenic effect Toxicity 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 206010002660 Anoxia Diseases 0.000 description 1
- 241000976983 Anoxia Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 241001074085 Scophthalmus aquosus Species 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- -1 When 60ml Chemical compound 0.000 description 1
- 239000008186 active pharmaceutical agent Substances 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000007953 anoxia Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 230000001146 hypoxic effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000036284 oxygen consumption Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 201000002859 sleep apnea Diseases 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61G—TRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
- A61G10/00—Treatment rooms or enclosures for medical purposes
- A61G10/02—Treatment rooms or enclosures for medical purposes with artificial climate; with means to maintain a desired pressure, e.g. for germ-free rooms
- A61G10/023—Rooms for the treatment of patients at over- or under-pressure or at a variable pressure
Landscapes
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Accommodation For Nursing Or Treatment Tables (AREA)
Abstract
This application discloses one kind can set simultaneously automatic control pneumatic and the low atmospheric pressure test device of oxygen content, comprising: closed observation container；Oxygen detector is connect with closed observation container；Store oxygen container；Unidirectional solenoid valve is connect with closed observation container and storage oxygen container respectively；Pressure detector is connect with closed observation container；Air exhauster is connect with closed observation container；Controller is connect with Unidirectional solenoid valve and air exhauster respectively；Processor is connect with controller, oxygen detector and pressure detector respectively, for calculating the runing time of air exhauster and the opening and closing time of Unidirectional solenoid valve based on gas pressure value and oxygen density value, and calculated result is sent to controller；And control panel, it is connect with processor.The device can be realized pumping after no longer there is low pressure anaerobic condition, keep it is hypobaric oxygen content also meets requirement of experiment simultaneously, to keep test result more accurate.
Description
Technical field
This application involves medical experiment field, can be set more particularly to one kind and automatic control pneumatic and oxygen content it is low
Air pressure experimental provision.
Background technique
Low pressure pathogenic effects test general performance of the main detection animal in low pressure, understand central nervous system machine
It can influence of the state to Hypoxia toleration.Low atmospheric pressure test device is the necessary equipment of low pressure pathogenic effects experiment, tradition dress
The method set is that vacuum desiccator is connected with air exhauster and mercury decompression meter respectively with two rubber tubes, presses the electricity of distribution board
Source switch starts air exhauster, so that air pressure is gradually decreased to 507mmHg respectively and (is equivalent to height above sea level 3000m height, oxygen content
16.15%), stop pumping, kept for 3~5 minutes, observe, record the activity condition of small white mouse, depth of respiration and frequency and tip
Then the indexs such as position (ear, lip, tail, sole) skin color decontrol the screw clamp on rubber tube, air pressure is made to restore normal.And
Start air exhauster again afterwards, make air pressure be gradually decreased to respectively 270mmHg (being equivalent to height above sea level 8000m height, oxygen content 8.51%),
150mmHg (is equivalent to height above sea level 10000m height, oxygen content 4.95%), repeats the above steps.The shortcomings that device is: power is not
Same air exhauster, the time for reaching setting atmospheric pressure value is different, even if its small power error of the identical air exhauster of two power
Or different working conditions reach setting same atmospheric pressure value the time required to be also not quite similar, experimental animal be in closed observation and holds
At any time all in oxygen consumption in device, the oxygen content in the more long closed observation container of air exhauster runing time is lower, reduced atmospheric pressure value with
Reduced oxygen content is disproportionate, and pumping, which also will cause, for a long time examines more severe depletion of oxygen in container, thereby results between each group
Observation condition it is inconsistent, indices change, and experimental result does not have comparativity between each group, not statistically significant.Solution
Certainly this key to the issue should set and automatic adjustable pressure value, set and automatically adjust oxygen content again, make to test between each group
It is consistent.
Summary of the invention
Aiming to overcome that the above problem or at least being partially solved or extenuate for the application solves the above problems.
According to the one aspect of the application, simultaneously automatic control pneumatic and the low pressure of oxygen content reality can be set by providing one kind
Experiment device, comprising:
Closed observation container, for accommodating experimental subjects；
Oxygen detector is connect with the closed observation container, dense for detecting the oxygen in the closed observation container
Angle value；
Oxygen container is store, for providing oxygen to the closed observation container；
Unidirectional solenoid valve is connect, for opening and closing respectively with the closed observation container and the oxygen reservoir container
State the oxygen outlet of storage oxygen container；
Pressure detector is connect with the closed observation container, for detecting the gas pressure in the closed observation container
Force value；
Air exhauster is connect with the closed observation container, for extracting the gas in the closed observation container out；
Controller is connect with the Unidirectional solenoid valve and the air exhauster respectively, for controlling the operation of the air exhauster
With the opening and closing of the Unidirectional solenoid valve；
Processor is connect with the controller, the oxygen detector and the pressure detector respectively, for being based on institute
State gas pressure value and the oxygen density value calculate the runing time of the air exhauster and the unlatching of the Unidirectional solenoid valve and
Shut-in time, and calculated result is sent to the controller；
Control panel is connected to the processor, for showing the gas pressure value and the oxygen density value, and
For receiving gas pressure setting value and oxygen concentration setting value set by user.
No longer there is low pressure anaerobic condition after can be realized pumping in the device, and hypobaric simultaneously in holding, oxygen contains
Amount also meets requirement of experiment, which eliminates amount of oxygen variation bring shadow while test for hypobaric
It rings, to keep test result more accurate.
Optionally, the pressure detector includes:
Baroceptor, for sensing the air pressure analog signal in the closed observation container；
First filter is connect with the baroceptor, for being filtered to the air pressure analog signal；
First amplifier is connect with the first filter, for amplifying the air pressure analog signal；
First converter is connect with first amplifier, for the air pressure analog signal to be converted to the gas
Body pressure value, and send the processor to.
Atmospheric pressure value in closed observation container can accurately be detected using the pressure detector.
Optionally, the oxygen detector includes:
Oxygen sensor, for sensing the oxygen concentration analog signal in the closed observation container；
Second filter is connect with the oxygen sensor, for being filtered to the oxygen concentration analog signal；
Second amplifier is connect with the second filter, for amplifying the oxygen concentration analog signal；
Second converter is connect with second amplifier, for the oxygen concentration analog signal to be converted to institute
Oxygen density value is stated, and sends the processor to.
Optionally, the processor includes:
Oxygen density value correction module is connect, for being based on respectively with the oxygen detector and the pressure detector
The gas pressure value is corrected the oxygen density value.
The device can make the corrected value true and accurate of oxygen density value using the oxygen density value correction module, and then right
The supplement of subsequent oxygen provides data foundation.
Optionally, the oxygen density value correction module is used for: carrying out school to the oxygen density value using following formula
Just:
Wherein, OX1Indicate oxygen density value；OX2Oxygen density value after indicating correction；P1Indicate gas pressure value；P2Table
Show air pressure standard value；K indicates correction coefficient.
Optionally, the controller is used for: it first controls the air exhauster and air suction process is carried out to the closed observation container,
The opening and closing of the Unidirectional solenoid valve are controlled again.
Therefore, which is first evacuated the waste for being oxygenated can reduce oxygen again, saves oxygen, extends the use of the device
Service life.
Optionally, the processor includes:
Pumping value computing module, connect with the oxygen detector, for being based on the gas pressure value, the gas pressure
The volume of power setting value and the closed observation container, calculates the first pumping value for needing to extract out；
Oxygen value computing module, connect with the oxygen detector, for based on the oxygen density value and described closed
The volume calculations for observing container need the first amount of oxygen to be offered；
Numerical value adjust module, respectively with the controller, the pumping value computing module and the oxygen value computing module
Connection, the volume based on the first pumping value, first amount of oxygen and the closed observation container, is adjusted by iterative calculation
The whole first pumping value and first amount of oxygen, obtain the second pumping value and second amount of oxygen, wherein adjustment
The second pumping value and second amount of oxygen afterwards enables to the closed observation gas in container to meet the gas
Pressure setting value and the oxygen concentration setting value, and when calculating the operation of the air exhauster based on the second pumping value
Between, the opening and closing time of the Unidirectional solenoid valve is calculated based on second amount of oxygen, by the runing time and described
The opening and closing time is sent to the controller.
The device is by the way of iterative calculation, without pumping and supplemental oxygen repeatedly, primary pumping and/or primary supplement
Oxygen can just make closed observation parameters in containers make it value.Therefore, adjustment time is saved, experiment essence is improved
Degree.
Optionally, the control panel for receive the user to the starting of the air exhauster, stopping, the speed of evacuation and
The setting value of the intake velocity of the oxygen reservoir container.
According to the accompanying drawings to the detailed description of the specific embodiment of the application, those skilled in the art will be more
Above-mentioned and other purposes, the advantages and features of the application are illustrated.
Detailed description of the invention
Some specific embodiments of the application are described in detail by way of example and not limitation with reference to the accompanying drawings hereinafter.
Identical appended drawing reference denotes same or similar part or part in attached drawing.It should be appreciated by those skilled in the art that these
What attached drawing was not necessarily drawn to scale.In attached drawing:
Fig. 1 be according to one embodiment of the application set and the low atmospheric pressure test of automatic control pneumatic and oxygen content
The schematic diagram of device；
Fig. 2 is the schematic diagram of the pressure detector of Fig. 1 shown device；
Fig. 3 is the schematic diagram of the oxygen detector of Fig. 1 shown device；
Fig. 4 is the schematic diagram of the processor of Fig. 1 shown device.
Specific embodiment
According to the accompanying drawings to the detailed description of the specific embodiment of the application, those skilled in the art will be more
Above-mentioned and other purposes, the advantages and features of the application are illustrated.
This application provides one kind can set simultaneously automatic control pneumatic and the low atmospheric pressure test device 100 of oxygen content.Fig. 1 is
According to one embodiment of the application set and the low atmospheric pressure test device of automatic control pneumatic and oxygen content it is schematic
Structure chart.The apparatus may include:
Closed observation container 110, for accommodating experimental subjects；
Oxygen detector 120 is connect with the closed observation container 110, for detecting in the closed observation container 110
Oxygen density value；
Oxygen container 130 is store, for providing oxygen to the closed observation container 110；
Unidirectional solenoid valve 140 is connect, for opening respectively with the closed observation container 110 and the oxygen reservoir container 130
With the oxygen outlet for closing the oxygen reservoir container 130；
Pressure detector 150 is connect with the closed observation container 110, for detecting in the closed observation container 110
Gas pressure value；
Air exhauster 160 is connect with the closed observation container 110, for extracting the gas in the closed observation container 110 out
Body；
Controller 170 is connect, for controlling the pumping respectively with the Unidirectional solenoid valve 140 and the air exhauster 160
The operation of machine 160 and the opening and closing of the Unidirectional solenoid valve 140；
Processor 180 connects with the controller 170, the oxygen detector 120 and the pressure detector 150 respectively
Connect, for calculated based on the gas pressure value and the oxygen density value air exhauster runing time and the unidirectional electricity
The opening and closing time of magnet valve, and calculated result is sent to the controller 170；
Control panel 190 is connect, for showing the gas pressure value and the oxygen concentration with the processor 180
Value, and for receiving gas pressure setting value and oxygen concentration setting value set by user.
The device is hypobaric simultaneously in holding by no longer there is low pressure anaerobic condition after pumping, oxygen content
Meet requirement of experiment, which eliminates amount of oxygen variation bring while test for hypobaric influence, from
And keep test result more accurate.
Fig. 2 is the schematic diagram of the pressure detector of Fig. 1 shown device.Optionally, the pressure detector 150 can
To include:
Baroceptor 210, for sensing the air pressure analog signal in the closed observation container；
First filter 220 is connect with the baroceptor 210, for being filtered to the air pressure analog signal；
First amplifier 230 is connect with the first filter 220, for amplifying the air pressure analog signal；
First converter 240 is connect with first amplifier 230, for being converted to the air pressure analog signal
The gas pressure value, and send the processor to.
The top cover in closed observation container can be set in the pressure detector, so as not to experimental subjects to the destruction of the component and
Damage.Atmospheric pressure value in closed observation container can accurately be detected using the pressure detector.
Fig. 3 is the schematic diagram of the oxygen detector of Fig. 1 shown device.Optionally, the oxygen detector 110 wraps
It includes:
Oxygen sensor 310, for sensing the oxygen concentration analog signal in the closed observation container；
Second filter 320 is connect with the oxygen sensor 310, for carrying out to the oxygen concentration analog signal
Filtering；
Second amplifier 330 is connect with the second filter 320, for carrying out the oxygen concentration analog signal
Amplification；
Second converter 340 is connect with second amplifier 330, for turning the oxygen concentration analog signal
It is changed to the oxygen density value, and sends the processor 180 to.
The top cover in closed observation container can be set in the oxygen detector, so as not to experimental subjects to the destruction of the component and
Damage.Oxygen density value in closed observation container can accurately be detected using the oxygen detector.
Fig. 4 is the schematic diagram of the processor of Fig. 1 shown device.Optionally, the processor 180 includes:
Oxygen density value correction module 310 is connect with the oxygen detector and the pressure detector respectively, is used for base
The oxygen density value is corrected in the gas pressure value.
Optionally, the oxygen density value correction module is used for: carrying out school to the oxygen density value using following formula
Just:
Wherein, OX1Indicate oxygen density value；OX2Oxygen density value after indicating correction；P1Indicate gas pressure value；P2Table
Show air pressure standard value；K indicates correction coefficient.
Since in the low pressure state, the measured value of oxygen can change, measurement result cannot reflect that closed observation is held
True oxygen concentration in device.The device can make the corrected value of oxygen density value true using the oxygen density value correction module
Accurately, and then to the supplement of subsequent oxygen data foundation is provided.
Optionally, the controller is used for: it first controls the air exhauster and air suction process is carried out to the closed observation container,
The opening and closing of the Unidirectional solenoid valve are controlled again.
In actual operation, a part in the oxygen newly injected can be made also therewith by extracting air out again due to injection oxygen
Extraction, causes the waste of oxygen, therefore, is first evacuated the waste for being oxygenated can reduce oxygen again, saves oxygen, extend the device
Service life.
Controller may include driving circuit and relay.Processor controls the on-off of relay by driving circuit,
When given high level signal, driving circuit turn-on relay closure is to control the start and stop of air exhauster.When air exhauster starting
The air that waiting will extract out in closed observation container reduces the air pressure in container；When air exhauster stops, if breather valve
It completely closes, air pressure will not change in closed observation container, and user can pass through " the ventilation on adjusting controller panel
Valve " knob makes air pressure change in container by the way that " ventilation " is arranged, and restores normal value.
With reference to Fig. 4, optionally, the processor 180 includes:
Pumping value computing module 410 is connect with the gas pressure detector 150, for based on the gas pressure value, described
The volume of gas pressure setting value and the closed observation container, calculates the first pumping value for needing to extract out；
Oxygen value computing module 420 connect with the oxygen detector 120 or oxygen density value correction module 310, is used for
Volume calculations based on the oxygen density value and the closed observation container need the first amount of oxygen to be offered；
Numerical value adjust module 430, respectively with the controller 170, the pumping value computing module 410 and the oxygen value
Computing module 420 connects, and the volume based on the first pumping value, first amount of oxygen and the closed observation container leads to
It crosses iterative calculation and adjusts the first pumping value and first amount of oxygen, obtain the second pumping value and second oxygen
Amount, wherein the second pumping value adjusted and second amount of oxygen enable to the closed observation gas in container
Meet the gas pressure setting value and the oxygen concentration setting value, and the pumping is calculated based on the second pumping value
The runing time of machine calculates the opening and closing time of the Unidirectional solenoid valve based on second amount of oxygen, by the operation
Time and the opening and closing time are sent to the controller.
The device can calculate sucking rate and note oxygen amount by way of iteration, for example, in the volume of closed observation container
Oxygen concentration 30%.If simply calculating sucking rate and amount of oxygen according to difference, it is assumed that the container from closed is needed to extract out
200ml air could make air pressure change to 270mmHg from 507mmHg.But if be supplemented a certain amount of oxygen, such as
When 60ml, atmospheric pressure value can change more than 270mmHg, need to be evacuated even supplemental oxygen again at this time again, by repeatedly
Operation can just make atmospheric pressure value and oxygen value in closed observation container reach experimental standard.The device is using the side iterated to calculate
Formula, without pumping and supplemental oxygen repeatedly, primary pumping and/or a supplemental oxygen can just make closed observation parameters in containers
Make it value.Therefore, adjustment time is saved, experimental precision is improved.
Optionally, the control panel 190 is for receiving the user to ventilation, the starting of the air exhauster, stopping, pumping
The setting value of the intake velocity of gas velocity degree and the oxygen reservoir container.
Control panel can control charactron by single-chip microcontroller and realize, the mode real-time display of charactron dynamic scan goes out to work as
Preceding value and setting value.Signal is selected when single-chip microcontroller gives charactron position, using buffer stage UN2803 after 74ls138 decoder
Select the wherein work of 8 Digital sum pipes.74ls138 decoder realizes the decoding of 3 lines to 8 lines, and UN2803 is used for level conversion
Control signal is negated, and drives load charactron.(the number to be shown when single-chip microcontroller transmission charactron segment encode to be shown
Binary code), by 74LS595 realize serial mode input parallel output, serial input terminal be DS foot, parallel output position is
Display of the Q0 to Q7 by triode Q2 to Q9 control charactron data.
Control panel can also be controlled and set by the cooperation realization of display screen and keyboard, mouse, button, knob；?
It can be realized by touch screen.
The obturation effect of the device is outstanding, easy to operate, being capable of fast quick-recovery air pressure using bayonet type breather valve.
(1) junction of air exhauster is provided with 3 bayonets on the top cover of closed observation container, there are 2 cards at breather valve
Mouthful, there are 2 bayonets at the device back side；
(2) PU pipe is inserted on plug, and plug is arranged on the top cover of closed observation container, is only needed when accessing PU pipe
By PU pipe be inserted into bayonet, bayonet switch will clamping PU pipe, PU pipe is inserted into connector bottom, pipe is plugged post-tensioning once, confirmation
Pipe can not pull out；
(3) when removing PU pipe, green card cap need to be only depressed, bayonet switch is just opened, and can remove connection PU pipe at this time；
(4) mark on breather valve is atmosphere with fork into closed observation container direction downwards.
The installation procedure of the device is as follows:
(1) vacuum grease is smeared on plug when the plug of closed observation container is installed；
(2) breather valve is inserted directly into the end beyond the Great Wall of closed observation container；
(3) by the top cover of closed observation container, engagement edge smears vacuum grease, and adjustment is close.
(4) on the top cover of closed observation container lateral position there are two interface, respectively with device rear end air inlet and air pressure
Detection mouth is connected.
The experimental method of device provided by the present application may comprise steps of: opening the top cover of closed observation container, takes
It is nascent and Adult mouse each one, be put into closed observation container, observation, record small white mouse general activity situation, breathe
Depth and frequency and tip position (ear, lip, tail, sole) skin color.The top cover for covering closed observation container, is closed closed sight
Container is examined to be allowed to seal.Set gas pressure value and oxygen density value, start to test, make air pressure be gradually decreased to respectively 507mmHg,
270mmHg, 150mmHg, oxygen density value can be set in 250mg/L between 350mg/L, preferably 310mg/L.
When atmospheric pressure value reaches setting atmospheric pressure value, air exhauster stops working, when air pressure raising is more than setting value 5mmHg,
Device reduces air pressure automatically into program, pumping, and continual and steady hypobaric is observed above-mentioned when stable gas pressure is in setting value
Index notices it is why not same that two small white mouses have.When spasm occurs for adult rats, breather valve knob is opened immediately, restores air pressure
Normally, drier is opened, observes why not together two small white mouses have.
The device operation interface is simple and practical, and safety of deflating, shirtsleeve operation keeps teaching and scientific research more convenient.Air pressure drop
The behaviouristics of observation animal and body surface variation are also very intuitive after low, and pumping and deflation course are completed within a short period of time, are made
Experiment becomes easily quick；Process control is evacuated so that experimentation is more stable reliable, and error is small, conveniently obtains objective knot
By.It takes a substantial amount of time student no longer for inaction, invalid operation in an experiment, limited time and efforts is applied to brill
It grinds experimental technique, observation anoxia phenomenon, culture manipulative ability, think deeply in anoxic mechanism, greatly improve conventional efficient and effect.It
Also heart and brain guard system disease research can be carried out for undergraduate, design " anoxic experimental model ", implement university student's scientific and technical innovation item
Mesh has built a brand-new technology platform.The device of the application can be also used for relevant scientific experiment such as anoxic, obstructive
The duplication of the models such as sleep apnea syndrome, hypoxic precondition, has broad application prospects.
Experiment shows that the reform of device novelty replicates the means of whole mammal anoxic experimental model, real
Now to the fine adjustment of pressure control and control.For the device without mercury, use is safe；Pipeline sealing, air pressure adjustment range reach
600mmHg, stable gas pressure (error < 5mmHg)；The device uses integrated design, high-precision, and atmospheric pressure value sets convenient, flexible etc.
Advantage.Device Mr. Yu's University Medical College, pharmaceutical college, School of Public Health, School of Stomatology, nursing college 5
The experimental teaching of two subject of institute's undergraduate course, the Medical Science Function Comprehensive Experiment of College Students and pharmacological experiment, be school it is multi-specialized,
It is multidisciplinary to share, the inside and outside student in school is faced every year up to 1000 people.After the device, practical teaching is significantly improved to student's
The culture of manipulative ability, hence it is evident that improve the success rate and experimental teaching efficiency of experiment, while Faculty and Students also being made to be in one
In the experimental situation of safety.
Professional should further appreciate that, described in conjunction with the examples disclosed in the embodiments of the present disclosure
Unit and algorithm steps, can be realized with electronic hardware, computer software, or a combination of the two, hard in order to clearly demonstrate
The interchangeability of part and software generally describes each exemplary composition and step according to function in the above description.
These functions are implemented in hardware or software actually, the specific application and design constraint depending on technical solution.
Professional technician can use different methods to achieve the described function each specific application, but this realization
It is not considered that exceeding scope of the present application.
Those of ordinary skill in the art will appreciate that realizing that the modules in above-described embodiment processor can also pass through
Method and step realizes that this method step can be by program come instruction processing unit completion, and the program can store in calculating
In machine readable storage medium storing program for executing, the storage medium is non-transitory (English: non-transitory) medium, such as arbitrary access
Memory, read-only memory, flash memory, hard disk, solid state hard disk, tape (English: magnetic tape), floppy disk (English
Text: floppy disk), CD (English: optical disc) and any combination thereof.
The preferable specific embodiment of the above, only the application, but the protection scope of the application is not limited thereto,
Within the technical scope of the present application, any changes or substitutions that can be easily thought of by anyone skilled in the art,
Should all it cover within the scope of protection of this application.Therefore, the protection scope of the application should be with scope of protection of the claims
Subject to.
Claims (8)
1. one kind can be set and the low atmospheric pressure test device of automatic control pneumatic and oxygen content, comprising:
Closed observation container, for accommodating experimental subjects；
Oxygen detector is connect with the closed observation container, for detecting the oxygen density value in the closed observation container；
Oxygen container is store, for providing oxygen to the closed observation container；
Unidirectional solenoid valve is connect, for opening and closing the storage respectively with the closed observation container and the oxygen reservoir container
The oxygen outlet of oxygen container；
Pressure detector is connect with the closed observation container, for detecting the gas pressure value in the closed observation container；
Air exhauster is connect with the closed observation container, for extracting the gas in the closed observation container out；
Controller is connect with the Unidirectional solenoid valve and the air exhauster respectively, for controlling operation and the institute of the air exhauster
State the opening and closing of Unidirectional solenoid valve；
Processor is connect with the controller, the oxygen detector and the pressure detector respectively, for being based on the gas
Body pressure value and the oxygen density value calculate the runing time of the air exhauster and the opening and closing of the Unidirectional solenoid valve
Time, and calculated result is sent to the controller；With
Control panel is connected to the processor, and for showing the gas pressure value and the oxygen density value, and is used for
Receive gas pressure setting value and oxygen concentration setting value set by user.
2. the apparatus according to claim 1, which is characterized in that the pressure detector includes:
Baroceptor, for sensing the air pressure analog signal in the closed observation container；
First filter is connect with the baroceptor, for being filtered to the air pressure analog signal；
First amplifier is connect with the first filter, for amplifying the air pressure analog signal；With
First converter is connect with first amplifier, for the air pressure analog signal to be converted to the gas pressure
Force value, and send the processor to.
3. device according to claim 1 or 2, which is characterized in that the oxygen detector includes:
Oxygen sensor, for sensing the oxygen concentration analog signal in the closed observation container；
Second filter is connect with the oxygen sensor, for being filtered to the oxygen concentration analog signal；
Second amplifier is connect with the second filter, for amplifying the oxygen concentration analog signal；With
Second converter is connect with second amplifier, for the oxygen concentration analog signal to be converted to the oxygen
Gas concentration value, and send the processor to.
4. device according to any one of claim 1 to 3, which is characterized in that the processor includes:
Oxygen density value correction module is connect with the oxygen detector and the pressure detector respectively, for based on described
Gas pressure value is corrected the oxygen density value.
5. device according to claim 4, which is characterized in that the oxygen density value correction module is used for: using as follows
Formula is corrected the oxygen density value:
Wherein, OX1Indicate oxygen density value；OX2Oxygen density value after indicating correction；P1Indicate gas pressure value；P2Indicate gas
Press standard value；K indicates correction coefficient.
6. device according to any one of claim 1 to 5, which is characterized in that the controller is used for: first described in control
Air exhauster carries out air suction process to the closed observation container, then controls the opening and closing of the Unidirectional solenoid valve.
7. device according to any one of claim 1 to 5, which is characterized in that the processor includes:
Pumping value computing module, connect with the oxygen detector, for being set based on the gas pressure value, the gas pressure
The volume for setting value and the closed observation container, calculates the first pumping value for needing to extract out；
Oxygen value computing module, connect with the oxygen detector, for being based on the oxygen density value and the closed observation
The volume calculations of container need the first amount of oxygen to be offered；With
Numerical value adjusts module, connect respectively with the controller, the pumping value computing module and the oxygen value computing module,
Volume based on the first pumping value, first amount of oxygen and the closed observation container, adjusts institute by iterative calculation
The first pumping value and first amount of oxygen are stated, obtains the second pumping value and second amount of oxygen, wherein adjusted
The second pumping value and second amount of oxygen enable to the closed observation gas in container to meet the gas pressure
Setting value and the oxygen concentration setting value, and calculate based on the second pumping value the runing time of the air exhauster, base
Calculate the opening and closing time of the Unidirectional solenoid valve in second amount of oxygen, by the runing time and it is described unlatching and
Shut-in time is sent to the controller.
8. device according to any one of claim 1 to 7, which is characterized in that the control panel is described for receiving
Setting value of the user to the intake velocity of the starting of the air exhauster, stopping, the speed of evacuation and the oxygen reservoir container.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110420311.3A CN113116662B (en) | 2018-11-27 | 2018-11-27 | Low-pressure experimental device |
| CN201811429178.2A CN109620597B (en) | 2018-11-27 | 2018-11-27 | Low-pressure experimental device capable of setting and automatically controlling air pressure and oxygen content |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201811429178.2A CN109620597B (en) | 2018-11-27 | 2018-11-27 | Low-pressure experimental device capable of setting and automatically controlling air pressure and oxygen content |
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| CN202110420311.3A Division CN113116662B (en) | 2018-11-27 | 2018-11-27 | Low-pressure experimental device |
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| CN109620597B CN109620597B (en) | 2021-05-28 |
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| CN201811429178.2A Active CN109620597B (en) | 2018-11-27 | 2018-11-27 | Low-pressure experimental device capable of setting and automatically controlling air pressure and oxygen content |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113520759A (en) * | 2021-06-21 | 2021-10-22 | 浙江科技学院 | Pressure boost oxygenation device for plateau environment |
| WO2021238286A1 (en) * | 2020-05-26 | 2021-12-02 | 上海艾众生物科技有限公司 | Gas introducing device for bioreactor |
| CN114322161A (en) * | 2022-01-06 | 2022-04-12 | 中国人民解放军总医院 | Medical shelter integrating ICU (intensive care unit), negative pressure isolation, oxygen-enriched treatment and positive pressure protection functions |
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Also Published As
| Publication number | Publication date |
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| CN109620597B (en) | 2021-05-28 |
| CN113116662B (en) | 2022-04-26 |
| CN113116662A (en) | 2021-07-16 |
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