CN109602892A - A kind of oyster peptide composition of quick kidney tonifying and preparation method thereof - Google Patents

A kind of oyster peptide composition of quick kidney tonifying and preparation method thereof Download PDF

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Publication number
CN109602892A
CN109602892A CN201910047530.4A CN201910047530A CN109602892A CN 109602892 A CN109602892 A CN 109602892A CN 201910047530 A CN201910047530 A CN 201910047530A CN 109602892 A CN109602892 A CN 109602892A
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powder
oyster
oyster peptide
kidney tonifying
peptide composition
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刘既辉
吴加梁
曾令武
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Guangdong Trace Element Biotechnology Co Ltd
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Guangdong Trace Element Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents

Abstract

The invention discloses the oyster peptide compositions of quick kidney tonifying, the oyster peptide composition of the quick kidney tonifying is made of following raw material, oyster Gly-His-Lys 35.416%-49.416%, D-sorbite 22.450%-27.450%, Testa sojae atricolor powder 5.483%-11.483%, ground cinnamon 1.621%-2.621%, rhizoma polygonati powder 0.897%-2.497%, wolfberry fruit powder 0.897%-2.497%, pueraria root powder 4.787%-8.787%, microcrystalline cellulose 4.344%-6.344%, sodium cellulose glycolate 2.066%-3.264%, magnesium stearate 0.597%-0.997%, edible essence 0.548%-1.148%, silica 0.548%-1 .148%, ginseng pulverate 0.548%-1.148%.The present invention has kidney-nourishing tonifying Qi, grows essence and reinforces the kidney, improves sexual function, soreness and weakness of waist and knees symptom is effectively relieved.

Description

A kind of oyster peptide composition of quick kidney tonifying and preparation method thereof
Technical field
The present invention relates to kidney tonifying technical field of pharmaceuticals, the oyster peptide composition of specially a kind of quick kidney tonifying and its preparation Method.
Background technique
Chinese medicine think kidney be internal organs this, 12 through root, the congenital foundation is kidney, and modern science proves, when human hair is raw When kidney deficiency, the immunocompetence of people can be made to reduce, be easy to induce many diseases.It is more next due to the increase of modern society's competitive pressure For more a middle-aged persons or adult because overworked, work and rest is irregular, drinking etc. leads to the symptom for kidney deficiency occur, kidney deficiency is kidney Metal fatigue, soreness and weakness of waist and knees, amnesia alopecia, impotence and premature ejaculation, male infertility caused by vital essence yin-yang is insufficient etc., causes to give birth to Function reduction is grown, people's lives and work are influenced, currently, the curative effect of existing a variety of kidney tonifying drugs or health care product is very in the market It is micro-, and the course for the treatment of is long.
Application No. is: CN201410261871.9 discloses a kind of Chinese medicine composition of blood rearing interpolating kidney, which grows Negative yang-tonifying, promoted immunity Chinese medicine composition with American Ginseng, gekko, radix achyranthis bidentatae, raspberry, hippocampus, turtle shell, Schisandra chinensis, ginseng, Dendrobium nobile, Radix changii, Cortex Eucommiae, root of kirilow rhodiola, Radix Astragali, Fructus Corni, dried human placenta, pilose antler, tortoiseshell, purslane, radix pseudostellariae, saussurea involucrata, lily, Sophora flower, radix polygonati officinalis, Radix Paeoniae Alba, cassia seed, mulberries and water blood rearing interpolating kidney Chinese materia medica preparation, adding brown sugar and honey later is raw material, By the way of for oral administration, daily three doses, 45 days courses for the treatment of, tests prove that can reach kidney-replenishing blood-nourishing, benefiting qi for promoting production of blood, raising is exempted from The effect of epidemic disease power.But the Chinese medicine composition treatment time is longer, and cannot using the composition of pilose antler, Cortex Eucommiae, hippocampus, radix achyranthis bidentatae etc. Demand of the male to nutrient is supplemented, the effect of quick kidney tonifying is not achieved, cannot preferably improve sexual function.
Application No. is: CN201711076023.0 to disclose a kind of oyster peptide pressed candy and preparation method thereof, the tabletting Candy is made of by weight following components: oyster peptide 25-35%, black ginger 5-15%, cortex cinnamomi 5-15%, rhizoma polygonati 2-7%, people Join 2-7%, Chinese yam 3-6%, Cordyceps militaris 3-6%, Herba Cistanches 3-6%, lycium ruthenicum 2-7%, arginine 3-6%, other auxiliary materials 10- 20%.The oyster peptide pressed candy can be improved liver function, improve the detoxification ability of liver, enhance the physical strength of male, this is male Although oyster peptide pressed candy has certain effect to enhancing male's physical strength aspect tool, can be used as a kind of every-day object, The curative effect of the oyster peptide pressed candy is slow, it is difficult to be difficult to take effect in a short time, treatment cost is high.
Summary of the invention
The present invention has kidney-nourishing tonifying Qi in view of the above-mentioned problems of the prior art, providing one kind, grows essence and reinforces the kidney, raising property Oyster peptide composition of quick kidney tonifying of soreness and weakness of waist and knees symptom and preparation method thereof is effectively relieved in function.
In order to achieve the above object, the present invention is achieved by the following technical programs: a kind of oyster polypeptide of quick kidney tonifying Composition is made of following raw material by mass percentage:
Oyster Gly-His-Lys 35.416%-49.416%, D-sorbite 22.450%-27.450%, Testa sojae atricolor powder 5.483%- 11.483%, ground cinnamon 1.621%-2.621%, rhizoma polygonati powder 0.897%-2.497%, wolfberry fruit powder 0.897%-2.497%, Pueraria root powder 4.787%-8.787%, microcrystalline cellulose 4.344%-6.344%, sodium cellulose glycolate 2.066%- 3.264%, magnesium stearate 0.597%-0.997%, edible essence 0.548%-1.148%, anticaking agent 0.548%- 1.148%, ginseng pulverate 0.548%-1.148%.
Further: by mass percentage, being made of following raw material: oyster Gly-His-Lys 42.416%, D-sorbite 25.450%, Testa sojae atricolor powder 8.483%, ground cinnamon 2.121%, rhizoma polygonati powder 1.697%, wolfberry fruit powder 1.697%, pueraria root powder 6.787%, microcrystalline cellulose 5.344%, sodium cellulose glycolate 2.664%, magnesium stearate 0.797%, edible essence 0.848%, anticaking agent 0.848%, ginseng pulverate 0.848%.
Further: by mass percentage, being made of following raw material: oyster Gly-His-Lys 39.916%, D-sorbite 24.968%, Testa sojae atricolor powder 10.463%, ground cinnamon 1.932%, rhizoma polygonati powder 2.397%, wolfberry fruit powder 2.127%, pueraria root powder 7.007%, microcrystalline cellulose 4.743%, sodium cellulose glycolate 2.998%, magnesium stearate 0.621%, edible essence 0.965%, anticaking agent 0.795%, ginseng pulverate 1.068%.
Further: by mass percentage, being made of following raw material: oyster Gly-His-Lys 40.342%, D-sorbite 25.736%, Testa sojae atricolor powder 10.728%, ground cinnamon 1.732%, rhizoma polygonati powder 1.336%, wolfberry fruit powder 1.823%, pueraria root powder 6.457%, microcrystalline cellulose 5.835%, sodium cellulose glycolate 3.008%, magnesium stearate 0.563%, edible essence 0.756%, anticaking agent 0.698%, ginseng pulverate 0.986%.
Further: by mass percentage, being made of following raw material: by mass percentage, being made of following raw material: oyster Gly-His-Lys 41.934%, D-sorbite 25.963%, Testa sojae atricolor powder 9.554%, ground cinnamon 2.056%, rhizoma polygonati powder 1.276%, Chinese holly Qi powder 1.498%, pueraria root powder 6.369%, microcrystalline cellulose 5.568%, sodium cellulose glycolate 2.488%, magnesium stearate 0.685%, edible essence 0.806%, anticaking agent 0.798%, ginseng pulverate 1.005%.
Further: the anticaking agent is silica.
7. a kind of preparation method of the oyster peptide composition of quick kidney tonifying, comprising the following steps:
1) oyster peptide Gly-His-Lys, Testa sojae atricolor powder, ground cinnamon, rhizoma polygonati powder, wolfberry fruit powder, pueraria root powder, people are weighed by weight percentage Ginseng powder, D-sorbite, sodium cellulose glycolate sieve with 100 mesh sieve after mixing, obtain polypeptide mixture;
2) weigh edible essence by weight percentage, by edible essence be added polypeptide mixture in and be added it is suitable go from Sub- water is stirred, and is placed in 60 DEG C of vacuum oven dry 130-150min after mixing evenly, is obtained dry granular;
3) magnesium stearate, microcrystalline cellulose, silica are weighed by weight percentage, and dry granular is smashed it through into 15 meshes, Then stearate, microcrystalline cellulose, silica is added, carries out tabletting after mixing.
Beneficial effects of the present invention:
Compared with prior art, the present invention wants raw material based on oyster Gly-His-Lys, with Testa sojae atricolor powder, ground cinnamon, rhizoma polygonati powder, Ma Coffee powder, ginseng pulverate, wolfberry fruit powder multiple efficacies synergy raw material combine according to a certain ratio, to faster and better kidney tonifying mend Gas improves sexual function, grows essence and reinforces the kidney, soreness and weakness of waist and knees symptom is effectively relieved.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described, Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all Belong to the scope of protection of the invention.
It is as follows the effect of main component used in the present invention:
Oyster Gly-His-Lys: having and improve level of serum testosterone, enhances male's sexual, and oyster peptide male rich in is necessary Nutrient, wherein biological zinc, selenium, arginine, taurine etc., have extremely important effect to function of male health care.
Testa sojae atricolor powder: calming the liver kidney-nourishing, nourishing yin and nourishing blood, blood-enriching tranquillizing.
Ground cinnamon: mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, warming meridian.
Rhizoma polygonati powder: boosting qi and nourishing yin, invigorating the spleen, moistening lung, kidney-nourishing.
Wolfberry fruit powder: tonifying kidney and benefiting sperm nourishes the liver to improve visual acuity, and promotes the production of body fluid to quench thirst.
Pueraria root powder: tonifying kidney and strengthening yang, beneficial lung fluid, the pituitary gland that people can be changed promote the secretion of sex hormone, as testosterone, DHEA, estrogen mention the effect for improving sexual function.
Ginseng pulverate: ginseng contains the mixture there are many ginsenoside, and ginsenoside can be by promoting endothelial cell release one Nitrogen oxide induces the smooth muscle relaxation of corpora cavernosa penis, has the function of tonifying kidney and strengthening yang.
Edible essence of the invention is lemon extract or vanilla.
Embodiment 1
The present embodiment provides a kind of oyster peptide compositions of quick kidney tonifying, by oyster Gly-His-Lys 42.416%, D-sorbite 25.450%, Testa sojae atricolor powder 8.483%, ground cinnamon 2.121%, rhizoma polygonati powder 1.697%, wolfberry fruit powder 1.697%, pueraria root powder 6.787%, microcrystalline cellulose 5.344%, sodium cellulose glycolate 2.664%, magnesium stearate 0.797%, lemon extract 0.848%, silica 0.848%, ginseng pulverate 0.848% are made;
The preparation method of the oyster peptide composition of the quick kidney tonifying, comprising the following steps: 1) press above-mentioned mass percent Take oyster peptide Gly-His-Lys, Testa sojae atricolor powder, ground cinnamon, rhizoma polygonati powder, wolfberry fruit powder, pueraria root powder, ginseng pulverate, D-sorbite, hydroxylmethyl cellulose Plain sodium sieves with 100 mesh sieve after mixing, obtains polypeptide mixture,
2) lemon extract is weighed by above-mentioned weight percent, lemon extract is added in polypeptide mixture and is added suitable Deionized water is stirred, and is placed in 60 DEG C of vacuum oven dry 145min after mixing evenly, is obtained dry granular;
3) magnesium stearate, microcrystalline cellulose, silica are weighed by above-mentioned weight percent, dry granular is smashed it through into 15 mesh Then sieve is added stearate, microcrystalline cellulose, silica, carries out tabletting after mixing.
Embodiment 2
The present embodiment provides a kind of oyster peptide compositions of quick kidney tonifying, by oyster Gly-His-Lys 39.916%, D-sorbite 24.968%, Testa sojae atricolor powder 10.463%, ground cinnamon 1.932%, rhizoma polygonati powder 2.397%, wolfberry fruit powder 2.127%, pueraria root powder 7.007%, microcrystalline cellulose 4.743%, sodium cellulose glycolate 2.998%, magnesium stearate 0.621%, vanilla 0.965%, silica 0.795%, ginseng pulverate 1.068% are made;
The preparation method of the oyster peptide composition of the quick kidney tonifying, comprising the following steps: 1) press above-mentioned mass percent Take oyster peptide Gly-His-Lys, Testa sojae atricolor powder, ground cinnamon, rhizoma polygonati powder, wolfberry fruit powder, pueraria root powder, ginseng pulverate, D-sorbite, hydroxylmethyl cellulose Plain sodium sieves with 100 mesh sieve after mixing, obtains polypeptide mixture,
2) vanilla is weighed by above-mentioned weight percent, vanilla is added in polypeptide mixture and is added suitable Deionized water is stirred, and is placed in 60 DEG C of vacuum oven dry 150min after mixing evenly, is obtained dry granular;
3) magnesium stearate, microcrystalline cellulose, silica are weighed by above-mentioned weight percent, dry granular is smashed it through into 15 mesh Then sieve is added stearate, microcrystalline cellulose, silica, carries out tabletting after mixing.
Embodiment 3
The present embodiment provides a kind of oyster peptide compositions of quick kidney tonifying, by oyster Gly-His-Lys 40.342%, D-sorbite 25.736%, Testa sojae atricolor powder 10.728%, ground cinnamon 1.732%, rhizoma polygonati powder 1.336%, wolfberry fruit powder 1.823%, pueraria root powder 6.457%, microcrystalline cellulose 5.835%, sodium cellulose glycolate 3.008%, magnesium stearate 0.563%, lemon extract 0.756%, silica 0.698%, ginseng pulverate 0.986% are made;
The preparation method of the oyster peptide composition of the quick kidney tonifying, comprising the following steps: 1) press above-mentioned mass percent Take oyster peptide Gly-His-Lys, Testa sojae atricolor powder, ground cinnamon, rhizoma polygonati powder, wolfberry fruit powder, pueraria root powder, ginseng pulverate, D-sorbite, hydroxylmethyl cellulose Plain sodium sieves with 100 mesh sieve after mixing, obtains polypeptide mixture;
2) lemon extract is weighed by above-mentioned weight percent, lemon extract is added in polypeptide mixture and is added suitable Deionized water is stirred, and is placed in 60 DEG C of vacuum oven dry 135min after mixing evenly, is obtained dry granular;
3) magnesium stearate, microcrystalline cellulose, silica are weighed by above-mentioned weight percent, dry granular is smashed it through into 15 mesh Then sieve is added stearate, microcrystalline cellulose, silica, carries out tabletting after mixing.
Embodiment 4
The present embodiment provides a kind of oyster peptide composition of quick kidney tonifying, oyster Gly-His-Lys 41.934%, D-sorbite 25.963%, Testa sojae atricolor powder 9.554%, ground cinnamon 2.056%, rhizoma polygonati powder 1.276%, wolfberry fruit powder 1.498%, pueraria root powder 6.369%, microcrystalline cellulose 5.568%, sodium cellulose glycolate 2.488%, magnesium stearate 0.685%, vanilla 0.806%, silica 0.798%, ginseng pulverate 1.005% are made;
The preparation method of the oyster peptide composition of the quick kidney tonifying, comprising the following steps: 1) press above-mentioned mass percent Take oyster peptide Gly-His-Lys, Testa sojae atricolor powder, ground cinnamon, rhizoma polygonati powder, wolfberry fruit powder, pueraria root powder, ginseng pulverate, D-sorbite, hydroxylmethyl cellulose Plain sodium sieves with 100 mesh sieve after mixing, obtains polypeptide mixture,
2) vanilla is weighed by above-mentioned weight percent, vanilla is added in polypeptide mixture and is added suitable Deionized water is stirred, and is placed in 60 DEG C of vacuum oven dry 140min after mixing evenly, is obtained dry granular;
3) magnesium stearate, microcrystalline cellulose, silica are weighed by above-mentioned weight percent, dry granular is smashed it through into 15 mesh Then sieve is added stearate, microcrystalline cellulose, silica, carries out tabletting after mixing.
The application of the oyster peptide composition of quick kidney tonifying of the invention:
The instructions of taking of oyster peptide composition of the invention, dosage: it is oral, it is 1-2 times daily, each 2-4 piece (specification: 0.4g/ piece), every five days as a treatment course.
In 150 clinical trials, wherein impotence, 50 people of Patients with Premature Ejaculation, 50 people of soreness and weakness of waist and knees patient, lassitude, 50 people of vigor immunocompromised patients.
1 control group of table
Table 2 takes the treatment results of the oyster peptide composition of the embodiment of the present invention 1
Table 3 takes the treatment results of the oyster peptide composition of the embodiment of the present invention 2
Table 4 takes the treatment results of the oyster peptide composition of the embodiment of the present invention 3
Table 5 takes the treatment results of the oyster peptide composition of the embodiment of the present invention 4
It can be seen from the above treatment results patient taken embodiment 1 of the present invention, embodiment 2,
Embodiment 3, embodiment 4 oyster peptide composition after, significantly can rapidly improve or eliminate impotence, premature ejaculation, The symptoms such as soreness and weakness of waist and knees, the effect compared to drugs such as existing alleviation impotence, premature ejaculation, soreness and weakness of waist and knees is more preferable, and the course for the treatment of is shorter, can Have the function that quick kidney tonifying, and optimal with the effect of the oyster peptide composition of the offer of embodiment 1.
The present invention using the oyster peptide containing arginine and abundant microelement as primary raw material, and with can play calming the liver kidney-nourishing Testa sojae atricolor powder, the ground cinnamon of mends fire supporing yang, literary qualcomm meridian, kidney-nourishing, invigorating the spleen can treat soreness and weakness of waist and knees, antifatigue rhizoma polygonati The raw material of powder, the wolfberry fruit powder that tonifying kidney and benefiting sperm promotes the production of body fluid to quench thirst, the pueraria root powder of tonifying kidney and strengthening yang and ginseng pulverate, multiple efficacies synergy are pressed Certain proportion combination, can more rapid and better reach improves male's sexual, antifatigue effect.
Oyster peptide composition of the invention is using D-sorbite as sweetener, while the mouthfeel of product can be improved, The effect of nutritional advantages with polyalcohol, low heat value, low sugar, anti-caries.
The above content is a further detailed description of the present invention in conjunction with specific preferred embodiments, and it cannot be said that Specific implementation of the invention is only limited to these instructions.For those of ordinary skill in the art to which the present invention belongs, exist Under the premise of not departing from present inventive concept, a number of simple deductions or replacements can also be made, all shall be regarded as belonging to of the invention Protection scope.

Claims (7)

1. a kind of oyster peptide composition of quick kidney tonifying, it is characterised in that: by mass percentage, be made of following raw material:
Oyster Gly-His-Lys 35.416%-49.416%, D-sorbite 22.450%-27.450%, Testa sojae atricolor powder 5.483%- 11.483%, ground cinnamon 1.621%-2.621%, rhizoma polygonati powder 0.897%-2.497%, wolfberry fruit powder 0.897%-2.497%, Ma Coffee powder 4.787%-8.787%, microcrystalline cellulose 4.344%-6.344%, sodium cellulose glycolate 2.066%-3.264%, Magnesium stearate 0.597%-0.997%, edible essence 0.548%-1.148%, anticaking agent 0.548%-1.148%, ginseng pulverate 0.548%-1.148%.
2. a kind of oyster peptide composition of quick kidney tonifying according to claim 1, it is characterised in that: by mass percentage, It is made of following raw material: oyster Gly-His-Lys 42.416%, D-sorbite 25.450%, Testa sojae atricolor powder 8.483%, ground cinnamon 2.121%, rhizoma polygonati powder 1.697%, wolfberry fruit powder 1.697%, pueraria root powder 6.787%, microcrystalline cellulose 5.344%, methylol are fine Tie up plain sodium 2.664%, magnesium stearate 0.797%, edible essence 0.848%, anticaking agent 0.848%, ginseng pulverate 0.848%.
3. a kind of oyster peptide composition of quick kidney tonifying according to claim 1, it is characterised in that: by mass percentage, It is made of following raw material: oyster Gly-His-Lys 39.916%, D-sorbite 24.968%, Testa sojae atricolor powder 10.463%, ground cinnamon 1.932%, rhizoma polygonati powder 2.397%, wolfberry fruit powder 2.127%, pueraria root powder 7.007%, microcrystalline cellulose 4.743%, methylol are fine Tie up plain sodium 2.998%, magnesium stearate 0.621%, edible essence 0.965%, anticaking agent 0.795%, ginseng pulverate 1.068%.
4. a kind of oyster peptide composition of quick kidney tonifying according to claim 1, it is characterised in that: by mass percentage, It is made of following raw material: oyster Gly-His-Lys 40.342%, D-sorbite 25.736%, Testa sojae atricolor powder 10.728%, ground cinnamon 1.732%, rhizoma polygonati powder 1.336%, wolfberry fruit powder 1.823%, pueraria root powder 6.457%, microcrystalline cellulose 5.835%, methylol are fine Tie up plain sodium 3.008%, magnesium stearate 0.563%, edible essence 0.756%, anticaking agent 0.698%, ginseng pulverate 0.986%.
5. a kind of oyster peptide composition of quick kidney tonifying according to claim 1, it is characterised in that: by mass percentage, Be made of following raw material: by mass percentage, being made of following raw material: oyster Gly-His-Lys 41.934%, D-sorbite 25.963%, Testa sojae atricolor powder 9.554%, ground cinnamon 2.056%, rhizoma polygonati powder 1.276%, wolfberry fruit powder 1.498%, pueraria root powder 6.369%, crystallite Cellulose 5.568%, sodium cellulose glycolate 2.488%, magnesium stearate 0.685%, edible essence 0.806%, anticaking agent 0.798%, ginseng pulverate 1.005%.
6. a kind of oyster peptide composition of quick kidney tonifying according to claim 1, it is characterised in that: the anticaking agent is two Silica.
7. a kind of preparation method of the oyster peptide composition of quick kidney tonifying, it is characterised in that: the following steps are included:
1) weigh by weight percentage oyster peptide Gly-His-Lys, Testa sojae atricolor powder, ground cinnamon, rhizoma polygonati powder, wolfberry fruit powder, pueraria root powder, ginseng pulverate, D-sorbite, sodium cellulose glycolate sieve with 100 mesh sieve after mixing, obtain polypeptide mixture;
2) edible essence is weighed by weight percentage, and edible essence is added in polypeptide mixture and suitable deionized water is added It is stirred, is placed in 60 DEG C of vacuum oven dry 130-150min after mixing evenly, obtains dry granular;
3) magnesium stearate, microcrystalline cellulose, silica are weighed by weight percentage, dry granular are smashed it through into 15 meshes, then Stearate, microcrystalline cellulose, silica is added, carries out tabletting after mixing.
CN201910047530.4A 2019-01-18 2019-01-18 A kind of oyster peptide composition of quick kidney tonifying and preparation method thereof Pending CN109602892A (en)

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Cited By (4)

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Publication number Priority date Publication date Assignee Title
CN111280364A (en) * 2020-04-17 2020-06-16 北京九鼎锐创生物医药科技社旗有限公司 Composite oyster and polygonatum peptide solid beverage and production process thereof
CN112675286A (en) * 2021-01-11 2021-04-20 梁宗杰 A pharmaceutical composition with kidney invigorating effect and its preparation
CN114748602A (en) * 2022-05-06 2022-07-15 四川必信科技有限公司 Cordyceps militaris double-ginseng tablet capable of tonifying kidney and strengthening vitality
CN115462522A (en) * 2021-09-23 2022-12-13 王伟华 Composition with effects of tonifying kidney, improving prostate and improving mental state

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CN103495027A (en) * 2013-10-10 2014-01-08 上海品纯健康科技有限公司 Ginseng-polygonatum sibiricum-cinnamomum cassia-gordon euryale seed food lozenge and preparation method thereof
CN108144040A (en) * 2017-08-01 2018-06-12 楼良水 The cordyceps sinensis oyster peptide complexes of kidney-tonifying sperm-generating

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CN103495027A (en) * 2013-10-10 2014-01-08 上海品纯健康科技有限公司 Ginseng-polygonatum sibiricum-cinnamomum cassia-gordon euryale seed food lozenge and preparation method thereof
CN108144040A (en) * 2017-08-01 2018-06-12 楼良水 The cordyceps sinensis oyster peptide complexes of kidney-tonifying sperm-generating

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111280364A (en) * 2020-04-17 2020-06-16 北京九鼎锐创生物医药科技社旗有限公司 Composite oyster and polygonatum peptide solid beverage and production process thereof
CN112675286A (en) * 2021-01-11 2021-04-20 梁宗杰 A pharmaceutical composition with kidney invigorating effect and its preparation
CN115462522A (en) * 2021-09-23 2022-12-13 王伟华 Composition with effects of tonifying kidney, improving prostate and improving mental state
CN114748602A (en) * 2022-05-06 2022-07-15 四川必信科技有限公司 Cordyceps militaris double-ginseng tablet capable of tonifying kidney and strengthening vitality

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