CN109602891A - A kind of external preparation for skin spraying mixt controlling weight - Google Patents
A kind of external preparation for skin spraying mixt controlling weight Download PDFInfo
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- CN109602891A CN109602891A CN201910055598.7A CN201910055598A CN109602891A CN 109602891 A CN109602891 A CN 109602891A CN 201910055598 A CN201910055598 A CN 201910055598A CN 109602891 A CN109602891 A CN 109602891A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/011—Hydrolysed proteins; Derivatives thereof from plants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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Abstract
The invention discloses a kind of external preparation for skin spraying mixts for controlling weight, using oligopeptides -1, soya-bean polypeptides, Bitter Melon P.E, Magnolia cortex P.E, apple extract as principle active component, aloe vera extract is used as skin moisturizing, glycerol, butanediol, Phenoxyethanol, pungent glycol are as solvent, deionized water is diluent, is wiped/sprayed in skin progress Transdermal absorption by applying.Using aloe vera extract viral infection resisting, the effect for promoting healing to restore, prevent harmful virus from taking advantage of the occasion to enter in vivo with mixture.Advantage is: can absorb effective substance in a manner of applying and be wiped/sprayed in skin and enter in vivo, promote leptin to generate, application method is simple.
Description
Technical field
The present invention relates to a kind of skin spraying mixt technical field more particularly to a kind of external application spraying for controlling weight are mixed
Close object.
Background technique
Obesity is a kind of chronic metabolic disease as caused by many factors, is divided into Secondary Obesity and pure fertilizer
It is fat.The cause of disease of Secondary Obesity is that endocrine metabolism exception occurs.For simple obesity without endocrine disturbance phenomenon, symptom is complete
Body Fat Distribution is relatively uniform, formative factor has heredity, diet is not scientific, amount of exercise is insufficient etc..Ways of preventing obesity in addition to
It adjusts diet, reinforce outside movement, can also be assisted using diet products.Assisting the product of weight-reducing in the market has edible leptin, leads to
Directly edible leptin is crossed, body fat storage is adjusted, accelerates metabolism, appetite-suppressing should to achieve the purpose that control weight
Type products have certain market prospects, but product type is single, only eats.Product diversification one is to being market development
Trend, research and develop the product of different types of control weight, such as external spray or the product of painting meet the market requirement.
Summary of the invention
The purpose of the present invention is to provide a kind of external preparation for skin spraying mixts for controlling weight, to adapt to market to product
Diversified demand.
In order to achieve the above object the present invention adopts the following technical scheme:
A kind of external preparation for skin spraying mixt controlling weight, calculates by mass percentage, is made of following component:
Further, it calculates, is made of following component by mass percentage:
Further, it calculates, is made of following component by mass percentage:
Further, it calculates, is made of following component by mass percentage:
Further, it calculates, is made of following component by mass percentage:
A kind of preparation method for the external preparation for skin spraying mixt controlling weight, steps are as follows:
(1) each ingredient is weighed according to the ratio;
(2) each effective component is pre-dissolved respectively;
(3) each ingredient that step (2) is pre-dissolved stirred evenly, stood;
(4) it filters, abandons filter residue;
(5) filtrate is by specification bottling, packaging.
Preferably, oil-soluble material is pre-dissolved with glycerol in the step (2), Water-solubility Material is pre-dissolved with deionized water;
Preferably, stirring rate is 40-90r/min in the step (3), and standing duration is for 24 hours.
Preferably, the Bitter Melon P.E includes triterpenoid.
The present invention has the advantages that
1. can in a manner of applying and be wiped/sprayed in skin, absorb soya-bean polypeptides, oligopeptides -1, the effective substances such as Bitter Melon P.E into
Enter in vivo, leptin is promoted to generate;Leptin adjusts body fat storage, accelerates metabolism, appetite-suppressing, to reach control weight
Purpose;
2. accelerating soya-bean polypeptides, oligopeptides -1, Bitter Melon P.E by relexation of the Magnolia cortex P.E to muscle and absorbing;
3. improving the excitatoty characteristic of nervous centralis using apple extract, soya-bean polypeptides, oligopeptides -1, balsam pear is accelerated to mention
Object stimulation leptin is taken to generate;
4. aloe vera extract viral infection resisting promotes healing to restore, avoids harmful virus being mixed into mixture.
Specific embodiment
Below in conjunction with specific embodiment, the present invention will be described in detail, herein with illustrative examples and explanation of the invention
For explaining the present invention, but it is not as a limitation of the invention.
A kind of external preparation for skin spraying mixt controlling weight, is mentioned with oligopeptides -1, soya-bean polypeptides, Bitter Melon P.E, Cortex Magnoliae Officinalis
Taking object, apple extract is principle active component, and aloe vera extract is used as skin moisturizing, glycerol, butanediol, benzene oxygen
As solvent, deionized water is diluent for ethyl alcohol, pungent glycol, is wiped/sprayed in skin progress Transdermal absorption by applying.It is drawn using library
Rope aloe extract viral infection resisting, the effect for promoting healing to restore prevent harmful virus from taking advantage of the occasion to enter in vivo with mixture.
It is to being explained further for inventive formulation:
Soya-bean polypeptides are to be digested soybean protein at the small molecule piece being made of 2 to 10 amino acid using biotechnology
Section, is easily absorbed by the body, as leptin protein donor;Oligopeptides -1 (Oligopeptide-1) is glycine and histidine and relies
The polymer of propylhomoserin composition also referred to as " transdermal peptide " is easy to be absorbed by the skin, as leptin protein donor.
Arhat saponin(e in balsam pear can enhance fatty acid oxidation and improve glucose utilization rate, Bitter Melon P.E (including three
Terpene compound) this bioactive substance can by promote leptin synthesis, thus reduce fat accumulation.
Magnolia cortex P.E effective component includes: honokiol, magnolol, magnolia bark total-phenol, with special, lasting flesh
Meat relexation and stronger antibacterial action, can inhibit platelet aggregation.Muscle is conducive under the relexation of Magnolia cortex P.E
Absorption of the capillary to soya-bean polypeptides, oligopeptides -1, Bitter Melon P.E etc.;Apple extract contains the Polyphenols object such as chlorogenic acid
Central excitatory can be improved in matter, chlorogenic acid, influences nervous centralis, improves Bitter Melon P.E, soya-bean polypeptides, oligopeptides in vivo defeated
Send efficiency.
Aloe vera extract has viral infection resisting, the effect for promoting healing to restore.
Glycerol, butanediol, Phenoxyethanol, pungent glycol have both antibacterial, moisture-keeping function as solvent.Deionized water is as dilution
Solvent.
Three embodiments exemplified below:
Ingredient | Embodiment one | Embodiment two | Embodiment three |
Glycerol | 8%; | 2%; | 4%; |
Butanediol | 6%; | 2%; | 3%; |
Soya-bean polypeptides | 4%; | 2%; | 1%; |
Oligopeptides -1 | 1%; | 0.2%; | 1%; |
Aloe vera extract | 0.5%; | 0.5%; | 1%; |
Phenoxyethanol | 3%; | 1.5%; | 2.5%; |
Pungent glycol | 1%; | 0.5%; | 0.5%; |
Bitter Melon P.E | 1%; | 0.1%; | 0.3%; |
Apple extract | 0.5%; | 0.1%; | 0.2%; |
Magnolia cortex P.E | 1%; | 0.1%; | 0.5%; |
Deionized water | Surplus. | Surplus. | Surplus. |
The preparation method of embodiment one, steps are as follows:
(1) each ingredient is weighed according to the ratio;
(2) oil-soluble material is pre-dissolved with glycerol, Water-solubility Material is pre-dissolved with deionized water;
It (3) is that 40-90r/min is stirred uniform, standing for 24 hours by rate each ingredient that step (2) is pre-dissolved;
(4) it filters, abandons filter residue;
(5) filtrate is by specification bottling, packaging.
The preparation method of embodiment two is referring to embodiment one, but the stirring rate in step (3) is 50r/min;
The preparation method of embodiment three is referring to embodiment one, but the stirring rate in step (3) is 80r/min.
In use, can spray or be coated on local skin by product of the present invention, smearing method and dosage are as follows:
Be applied to around navel with 2 drops (about 0.2mL)~8 drip (0.5mL) sprays/every time, after ear-lobe, neck Adam's apple two sides.
The mechanism of action of the invention is, using soya-bean polypeptides, oligopeptides -1, Bitter Melon P.E as effective substance, to be extracted by Cortex Magnoliae Officinalis
Relexation of the object to muscle improves the excitability of nervous centralis, the rush of Bitter Melon P.E using apple extract into human body
" leptin " is generated into protein donor soya-bean polypeptides, oligopeptides -1, leptin adjusts body fat storage, accelerates metabolism, inhibits
Appetite achievees the purpose that control weight.While Transdermal absorption, prevent harmful virus from taking advantage of the occasion to invade with aloe vera extract
Evil.With smearing, indirect edible mode, stimulates the generation of leptin;Usage mode is easy to be simple.
It is provided for the embodiments of the invention technical solution above to be described in detail, specific case used herein
The principle and embodiment of the embodiment of the present invention are expounded, the explanation of above embodiments is only applicable to help to understand this
The principle of inventive embodiments;At the same time, for those skilled in the art, according to an embodiment of the present invention, in specific embodiment party
There will be changes in formula and application range, in conclusion the contents of this specification are not to be construed as limiting the invention.
Claims (9)
1. a kind of external preparation for skin spraying mixt for controlling weight, it is characterised in that:
It calculates, is made of following component by mass percentage:
2. a kind of external preparation for skin spraying mixt for controlling weight according to claim 1, it is characterised in that:
It calculates, is made of following component by mass percentage:
3. a kind of external preparation for skin spraying mixt for controlling weight according to claim 2, it is characterised in that:
It calculates, is made of following component by mass percentage:
4. a kind of external preparation for skin spraying mixt for controlling weight according to claim 3, it is characterised in that:
It calculates, is made of following component by mass percentage:
5. a kind of external preparation for skin spraying mixt for controlling weight according to claim 3, it is characterised in that:
It calculates, is made of following component by mass percentage:
6. the preparation method of the external preparation for skin spraying mixt of -5 any a kind of control weight according to claim 1,
It is characterized in that:
Steps are as follows:
(1) each ingredient is weighed according to the ratio;
(2) each effective component is pre-dissolved respectively;
(3) each ingredient that step (2) is pre-dissolved stirred evenly, stood;
(4) it filters, abandons filter residue;
(5) filtrate is by specification bottling, packaging.
7. a kind of external preparation for skin spraying mixt for controlling weight according to claim 6, it is characterised in that:
Oil-soluble material is pre-dissolved with glycerol in the step (2), Water-solubility Material is pre-dissolved with deionized water.
8. a kind of external preparation for skin spraying mixt for controlling weight according to claim 6, it is characterised in that:
Stirring rate is 40-90r/min in the step (3), and standing duration is for 24 hours.
9. a kind of external preparation for skin spraying mixt for controlling weight according to claim 1, it is characterised in that:
The Bitter Melon P.E includes triterpenoid.
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CN201910055598.7A CN109602891A (en) | 2019-01-22 | 2019-01-22 | A kind of external preparation for skin spraying mixt controlling weight |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001354517A (en) * | 2000-06-12 | 2001-12-25 | Nobiriteii Corporation:Kk | Skin care preparation |
CN101336708A (en) * | 2008-08-13 | 2009-01-07 | 黎秋萍 | Soya-bean polypeptides weight reduction food |
CN102423374A (en) * | 2011-11-23 | 2012-04-25 | 桂林莱茵生物科技股份有限公司 | Pharmaceutical composition with antiobesity action |
CN104730174A (en) * | 2015-03-02 | 2015-06-24 | 西北大学 | Standard apple extract as well as preparation and analysis method of standard apple extract |
CN105859827A (en) * | 2016-04-14 | 2016-08-17 | 扬州梦晓生物工程有限公司 | Oligopeptides-1 active constituent extracting method |
CN107811907A (en) * | 2017-10-30 | 2018-03-20 | 周茂森 | A kind of body lotion for promoting subcutaneous fat to decompose |
-
2019
- 2019-01-22 CN CN201910055598.7A patent/CN109602891A/en active Pending
Patent Citations (6)
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JP2001354517A (en) * | 2000-06-12 | 2001-12-25 | Nobiriteii Corporation:Kk | Skin care preparation |
CN101336708A (en) * | 2008-08-13 | 2009-01-07 | 黎秋萍 | Soya-bean polypeptides weight reduction food |
CN102423374A (en) * | 2011-11-23 | 2012-04-25 | 桂林莱茵生物科技股份有限公司 | Pharmaceutical composition with antiobesity action |
CN104730174A (en) * | 2015-03-02 | 2015-06-24 | 西北大学 | Standard apple extract as well as preparation and analysis method of standard apple extract |
CN105859827A (en) * | 2016-04-14 | 2016-08-17 | 扬州梦晓生物工程有限公司 | Oligopeptides-1 active constituent extracting method |
CN107811907A (en) * | 2017-10-30 | 2018-03-20 | 周茂森 | A kind of body lotion for promoting subcutaneous fat to decompose |
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Application publication date: 20190412 |