CN109602626A - A kind of skin care item and preparation method thereof containing choline salicylate - Google Patents

A kind of skin care item and preparation method thereof containing choline salicylate Download PDF

Info

Publication number
CN109602626A
CN109602626A CN201811592507.5A CN201811592507A CN109602626A CN 109602626 A CN109602626 A CN 109602626A CN 201811592507 A CN201811592507 A CN 201811592507A CN 109602626 A CN109602626 A CN 109602626A
Authority
CN
China
Prior art keywords
skin care
raw material
skin
care item
choline salicylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811592507.5A
Other languages
Chinese (zh)
Inventor
张嘉恒
袁菊懋
王乐明
张基亮
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhuhai Zhongke Advanced Technology Research Institute Co Ltd
Original Assignee
Zhuhai Zhongke Advanced Technology Research Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhuhai Zhongke Advanced Technology Research Institute Co Ltd filed Critical Zhuhai Zhongke Advanced Technology Research Institute Co Ltd
Priority to CN201811592507.5A priority Critical patent/CN109602626A/en
Publication of CN109602626A publication Critical patent/CN109602626A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of skin care item and preparation method thereof containing choline salicylate, the raw material for preparing of the skin care item includes choline salicylate, solvent, moisturizer, thickener and skin conditioning agent.The raw material for preparing is divided into A phase and B phase, A phase raw material includes water, transparent xanthan gum, AVC, Sodium Hyaluronate, glycerol, dipotassium glycyrrhizinate, 1,3-BDO and NMF-50;B phase raw material includes niacinamide, glycerol caprylate, decoyl hydroximic acid, 1,2- pentanediol, hexylene glycol and choline salicylate;As follows prepared by step: A phase raw material S1, being added to the emulsion pot sterilized: being warming up to 80~90 DEG C, middling speed homogeneous 3-5min;20~40min of insulated and stirred;S2,40 DEG C of addition B phase raw materials are cooled to, stir evenly to obtain the skin care item.

Description

A kind of skin care item and preparation method thereof containing choline salicylate
Technical field
The present invention relates to daily chemicals fields, and in particular to a kind of skin care item and preparation method thereof containing choline salicylate.
Background technique
Facial mask is an important class in skin care item, and its most basic and most important purpose is to make up makeup removing and wash one's face Still insufficient cleaning cooperates other essential ingredients to realize other maintenance functions, such as replenishing water and preserving moisture, beauty on this basis White, anti-aging, Sage Extract etc..The principle of facial mask is temporarily isolating extraneous sky exactly using the of short duration time for being covered on face Gas and pollution, improve skin temperature, and the pore expansion of skin promotes sweat gland secretion and metabolism, makes in the oxygen content of skin It rises, is conducive to skin and excludes the product of epidermal cell metabolism and the oil substances of accumulation, the moisture in facial mask penetrates into table The cuticula of skin, skin become soft, and skin is naturally bright flexible.
Facial mask can be divided into eight major class according to function: 1) cleaning pack and one of the most common type facial mask can remove hair Dirt and extra grease in hole, and aging cutin is removed, keep skin salubrious, clean;2) moisture saver mask, primary efficacy at It is divided into moisturizer, by moisture lock in film, cutin-softening layer, and percutaneous absorption nutrition is helped, it is suitble to all kinds of skin;3) it releives face Film, skin of releiving rapidly, banishes the feeling of languor, and restores the gloss and elasticity of skin, is suitable for sensibility skin;4) extra firming facial mask, It is mainly used for pore refining, aufhellung wrinkle, being particularly suitable for no time goes to beauty parlor to be the women nursed;5) regenerating mask, This kind of facial mask includes plant essence, softens epidermal tissue, promotes skin metabolism, is suitable for stemness or water deficient skin;6) Whitening mask thoroughly removes dead skin cells, has both cleaning, whitening double effects, reappears skin young tender smooth, pale transparent; 7) the effect of moment whitening MASQUE APAISANT HYDRATANT, alternatively referred to as 5 minutes skin-care facial masks, moment reaches whitening and moisturizing;8) pore contraction front Film is mainly used for that dirt is sucked out while restraining pore, enables skin soft and moist full of gloss, be suitble to all skin types.
Choline is a kind of biostearin, while being also nutrient needed by human.It is the important component for constituting cell membrane, It is also one of the raw material of human body synthesis glycine.It is separated first from pig's bile by Andreas Strecker within 1864, It is synthesized chemically within 1866.The intracorporal choline of people, which has, greatly to be derived from food, and trimethylamine is broken down into large intestine. Choline is a kind of strong organic base, is the constituent of lecithin, exists among sphingomyelin, is that body can be changed methyl One source and the product for acting on synthesizing methyl, while being the precursor of acetylcholine again, it is also regarded as helping to mankind's brain Development and memory.Human body can also synthesize choline, therefore, not easily cause deficiency disease.Choline is heat-resisting, in processing and gastronomical process Loss seldom, under dry environment, has almost no change content of choline in some time storage food.Choline is lecithin Sphingomyelins important component, lecithin is phosphatidyl choline, is widely present in animals and plants.The mankind and rat milk A large amount of choline can be provided for newborn, it is ensured that the mechanism and multiple of fetus an d neonate acquisition choline.A small amount of phosphatide in film Composition, including phosphatidyl 01 derivatives, Cholinphospholipide, especially phosphatidyl choline and sphingomyelin, are that can amplify External signal or the bioactive molecule by generating inhibition second messenger abort signal process.Choline is also to regulating cell Apoptosis has the irreplaceable important specific function of other methyl donors.Choline has affinity to fat, can promote rouge Fat is transferred out by liver by blood with phospholipid form or is improved utilization of the fatty acid in liver itself, and prevents fat in liver Abnormal accumulation in dirty.If fat, which accumulates in, fatty liver occurs without choline in liver, in morbid state.Clinically, using choline Cirrhosis, hepatitis and other liver diseases are treated, are worked well.Choline and inositol (another vitamin B) are cooperated together to carry out Utilization to fat and cholesterol;Choline is a small number of one of substances that can pass through " blood brain barrier ".This " barrier " protects brain Portion is not influenced by the change of diet.But choline can enter brain cell by this " barrier ", manufacture the chemistry being memonic Substance.Currently, the skin care effect research for choline is relatively fewer, choline is added in the cosmetics of part, but due to choline Stability is bad, causes effect still not ideal enough.
Salicylic acid is a kind of fat-soluble organic acid, and salicylic acid (ingredient in aspirin and many anodyne) is facing It is used to reduce the long-term concurrent cardiopathic risk of diabetic in bed test.Salicylic acid has fat-soluble feature, can be light Pine disintegrates the extra sebum of skin surface, is cleaned by being merged with lipid to the pore of skin, can help skin Skin exfoliating.Meanwhile salicylic acid also has the function of oil-control anti-acne, can disintegrate extra sebum, while skin being inhibited excessively to divide It secretes, plays the role of oil-control, for also having stronger dissolution because sebum blocks the keratotic plug to be formed, small pox etc., improve hair follicle The unclean state of wall helps sebum smoothly to exclude from pore, corrects abnormal cell detachment, can to slight whelk Prevent pore from blocking, it is most effective to blackhead;Salicylic acid plays the role of reducing pore, can be along the sebaceous glands of secretion grease The deep layer for going deep into pore is conducive to the cuticula for dissolving old accumulation in pore, improves the situation of pore obstruction, therefore can block The pore that the formation and diminution of acne are stretched;Salicylic acid has the function of deceleration aging, and the cuticula of skin can automatically update It regenerates, if old cutin does not fall off normally, skin will be made to seem coarse obscure, make skin metabolism rate slack-off, And salicylic acid can remove old useless cutin, promote epidermal cell quickly to update, when epidermal cell is all fresh and full of vitality Young tender cell when, the natural aging that can slow down skin allows skin to restore smooth careful;Salicylic acid has the work of Whitening, spot With in unsound keratinocyte layer, it will usually there is the case where skin surface pigment deposition, and salicylic acid can help to remove this One layer of aging cutin cell, prevents pigment deposition, in addition, salicylic acid can assist the infiltration of other acids whitening compositions, so through It is often added in the form of compound in the essence of Whitening, spot, helps the potential spot for fighting skin bottom.
Has the multiple function such as moisturizing, moisturizing, whitening, crease-resistant in conclusion still lacking can integrate simultaneously in the prior art The skin-protection product of effect is expected to be developed based on natural ion salt if can be added to choline and salicylic acid in skin care item simultaneously The skin-protection products such as youth facial mask, there are the multiple effects such as permanent moisturizing and anti-oxidant anti-inflammatory antiallergy.
Summary of the invention
The technical problems to be solved by the present invention are: providing a kind of more with permanent moisturizing and anti-oxidant anti-inflammatory antiallergy etc. The skin care item and preparation method thereof containing choline salicylate of weight effect.
In order to solve the above-mentioned technical problem, a kind of the technical solution adopted by the present invention are as follows: shield containing choline salicylate The raw material for preparing of skin product, the skin care item includes choline salicylate, solvent, moisturizer, thickener and skin conditioning agent.
Further, the solvent is deionized water.
Further, the moisturizer includes transparent xanthan gum, Sodium Hyaluronate, glycerol, 1,3-BDO, natural methyl group Sweet amino proline -50 (Natural Ami Methylglycine proline-50, NMF-50), hexylene glycol.
Further, the thickener includes ammonium acryloyl taurate/VP copolymer (ammonium Acryloyldimethyltaurate/VP copolymer, AVC), glycerol caprylate, decoyl hydroximic acid and 1,2- pentanediol.
Further, the skin conditioning agent includes niacinamide and dipotassium glycyrrhizinate.
Further, the weight accounting for preparing choline salicylate described in raw material is 0.01~1%.
Further, the raw material for preparing is made of choline salicylate, solvent, moisturizer and skin conditioning agent, wherein The weight accounting of the moisturizer is 8~15%, and the weight accounting of the thickener is 0.1~1%;The skin conditioning agent Weight accounting is 0.5~3%, and the solvent is surplus.
Further, the skin care item are youth facial mask.
The beneficial effects of the present invention are: the present invention program provides a kind of skin care item formula added with natural ion salt And preparation method, it can effectively solve in background technique skin refreshing existing for the skin care item such as facial mask is poor, effect is insufficient etc. Problem;The skin care item such as facial mask in the prior art, because of ingredient and during preparing, functional component type compatibility is unreasonable, easily The problems such as causing skin allergy.Not only ingredient is scientific and reasonable for the mildy wash of biological ion salt, but also safe ready, the present invention program " natural ion salt " choline salicylate (preparing with green chemical synthesis technology) is added, dissolubility is than mono-acid bigcatkin willow acid dissolution Property about 3 orders of magnitude of enhancing, can be good at locking moisture of skin, avoid skin water loss and the dry skin that causes.It should The thermal stability of natural ion salt reaches 150 degrees Celsius, i.e. inoxidizability and anti-inflammatory bactericidal properties, enhances the wetting to skin and guarantor Shield.Since this natural ion salt is based on choline cation and anionic salicylate, from extracted form natural plant, therefore, energy Enough as the important functional component in cosmetic formulations.
The invention also includes the preparation method of the above-mentioned skin care item containing choline salicylate, the solvent is water, described Moisturizer includes transparent xanthan gum, Sodium Hyaluronate, glycerol, 1,3-BDO, NMF-50, hexylene glycol;The thickener includes AVC, glycerol caprylate, decoyl hydroximic acid and 1,2- pentanediol;The skin conditioning agent includes niacinamide and dipotassium glycyrrhizinate;
The raw material for preparing is divided into A phase and B phase, A phase raw material includes water, transparent xanthan gum, AVC, Sodium Hyaluronate, sweet Oil, dipotassium glycyrrhizinate, 1,3-BDO and NMF-50;B phase raw material includes niacinamide, glycerol caprylate, decoyl hydroximic acid, 1,2- Pentanediol, hexylene glycol and choline salicylate;
As follows prepared by step:
S1, A phase raw material is added to the emulsion pot sterilized: first the water as solvent is added in the emulsion pot, It adds and accounts for the consumption water for preparing raw material weight 2~4%, then transparent xanthan gum, AVC and Sodium Hyaluronate are immersed in water completely In, the emulsion pot to be opened into homogeneous and is stirred to after being completely dispersed, the remaining ingredient put into A phase raw material is warming up to 80~90 DEG C, Middling speed homogeneous 3-5min;20~40min of insulated and stirred;
S2,40 DEG C of addition B phase raw materials are cooled to, stir evenly to obtain the skin care item.
Further, in the step S1, the middling speed is 400-500rpm/min.
Detailed description of the invention
Fig. 1 is the operational flowchart of the embodiment of the present invention.
Specific embodiment
To explain the technical content, the achieved purpose and the effect of the present invention in detail, below in conjunction with embodiment and cooperate attached Figure is explained.
The embodiment of the present invention are as follows: a kind of youth facial mask containing choline salicylate, the youth facial mask is by following preparation Raw material is prepared: solvent: deionized water;Moisturizer: transparent xanthan gum, Sodium Hyaluronate (small molecule), glycerol, 1,3- fourth two Alcohol, NMF-50, hexylene glycol;Thickener: AVC, A631 (glycerol caprylate, decoyl hydroximic acid and 1,2- pentanediol);Skin condition Agent: niacinamide and dipotassium glycyrrhizinate.
It prepares raw material by above-mentioned and is divided into A, B and C phase raw material by such as the following table 1 rule:
The separate classification chart of 1 raw material of table
The above-mentioned preparation method containing choline salicylate youth facial mask, as shown in Figure 1, comprising the following steps:
Step 1): with pure hot water washing and sterilizing emulsion pot;
Step 2): deionized water (adding 3% consumption water) is added in emulsion pot, transparent xanthan gum, AVC and transparent is added Matter acid sodium (small molecule) is immersed in water completely, and emulsion pot is opened homogeneous and stirred to after being completely dispersed, after putting into A phase surplus material, It is warming up to 85 DEG C, middling speed (450rpm) homogeneous 3-5 minutes, insulated and stirred 30 minutes;
Step 3): 40 DEG C of addition B phase materials are cooled to, stirs evenly, takes the dish out of the pot after the assay was approved, then inspection waits discharging;
Step 4): sealing storage vat after discharging, and moves between standing for use.
Step 5): semi-finished product dispense after quality inspection is qualified;
Step 6): packaging coding obtains finished product, is put in storage.
Wherein, the testing result in step 5) is as shown in table 2 below:
2 testing result table of table
As can be seen from Table 2, youth facial mask made from the present invention program is safe and reliable.
The effect assessment of youth facial mask made from aforesaid operations is tested:
Effect identification is carried out to youth facial mask whitening anti-wrinkling effect, investigates the using effect of youth facial mask of the invention.Choosing 30 volunteers are selected, every three days using once, is compared, is obtained such as the following table 3 before not using after 2 months and the youth facial mask Shown in result.
The using effect statistical form of 3 youth of table facial mask
As can be seen from Table 3, facial mask made from the present invention program not only has the effect of whitening and moisturizing, but also can dispel Acne is applicable to solve a variety of skin problems.Youth facial mask of the invention can be with the regulation of qi and blood, dredging the channel, nourishes rough skin, shining Pastiness spring skin can effectively solve the problems, such as the skin that the pigmentations such as chloasma, whelk cause.
Niacinamide has good whitening effect in the present invention program, can speed up metabolism, promotes to contain melanin Horn cell fall off, moreover it is possible to act on the melanin generated, reduce it and shifted to cells of superficial layer, and epidermis can be promoted The synthesis of layer protein, improves skin quality, simultaneously as causing skin containing a small amount of niacin in its raw material of Chang Yiyin in niacinamide Skin stimulation, and there is good anti-inflammatory antiallergy effect added with choline gallate and dipotassium glycyrrhizinate in the present invention program Fruit avoids niacinamide from side effect occur, in addition, choline gallate, Sodium Hyaluronate etc., which also have, cooperates with oxidation resistant work With therefore, the present invention program toner has safely and effectively white-skinned face function, in conjunction with P10 extract, choline gallate sheet Good moisturizing water lock effect possessed by body, so that the present invention program has good skin effect.
Youth facial mask in the prior art is dazzling, and some youth facial masks only have moisturizing, moistening effect, as beauty Other effect the effect of property such as white, crease-resistant are very weak;Some youth facial masks have skin sliminess, not enough moisten and salubrious;Have Youth facial mask has whitening, anti-senescence function, but being irritating to the skin property, destruction keratoderma cause sensitive skin;Also Some facial mask moistening effects are not permanent, frequently will cause excessive moisturizing using the facial mask, and Skin Cell gap is made to become larger, bacterium, Impurity etc. is easier to enter skin, is easier to long acne, and if things go on like this, can destroy the protective capability of skin itself, become very It is fragile.For this purpose, the present invention program proposes the exploitation of the youth mask product based on natural ion salt, there is permanent moisturizing to have both anti- Aoxidize anti-inflammatory antianaphylactic effect.
Above-described embodiment illustrates for for youth facial mask, but the present invention program can also be used for other similar having moisturizing simultaneous In the skin care item for having anti-oxidant anti-inflammatory antiallergy effect.
The above description is only an embodiment of the present invention, is not intended to limit the scope of the invention, all to utilize this hair Equivalents made by bright specification and accompanying drawing content are applied directly or indirectly in relevant technical field, similarly include In scope of patent protection of the invention.

Claims (9)

1. a kind of skin care item containing choline salicylate, it is characterised in that: the raw material for preparing of the skin care item includes choline water Poplar hydrochlorate, solvent, moisturizer, thickener and skin conditioning agent.
2. the skin care item according to claim 1 containing choline salicylate, it is characterised in that: the moisturizer includes saturating Framingham raw rubber, Sodium Hyaluronate, glycerol, 1,3-BDO, NMF-50 and hexylene glycol.
3. the skin care item according to claim 1 containing choline salicylate, it is characterised in that: the thickener includes AVC, glycerol caprylate, decoyl hydroximic acid and 1,2- pentanediol.
4. the skin care item according to claim 1 containing choline salicylate, it is characterised in that: the skin conditioning agent packet Include niacinamide and dipotassium glycyrrhizinate.
5. the skin care item according to claim 1-4 containing choline salicylate, it is characterised in that: the preparation The weight accounting of choline salicylate described in raw material is 0.01~1%.
6. the skin care item according to claim 5 containing choline salicylate, it is characterised in that: the raw material for preparing is by gallbladder Alkali salicylate, solvent, moisturizer and skin conditioning agent composition, wherein the weight accounting of the moisturizer is 8~15%, institute The weight accounting for stating thickener is 0.1~1%;The weight accounting of the skin conditioning agent is 0.5~3%, and the solvent is remaining Amount.
7. the skin care item according to claim 1-4 containing choline salicylate, it is characterised in that: the skin care Product are youth facial mask.
8. a kind of preparation method of the skin care item containing choline salicylate as described in claim 1, it is characterised in that: described Solvent is water, and the moisturizer includes transparent xanthan gum, Sodium Hyaluronate, glycerol, 1,3-BDO, NMF-50, hexylene glycol;Institute Stating thickener includes AVC, glycerol caprylate, decoyl hydroximic acid and 1,2- pentanediol;The skin conditioning agent include niacinamide and Dipotassium glycyrrhizinate;
The raw material for preparing is divided into A phase and B phase, A phase raw material include water, transparent xanthan gum, AVC, Sodium Hyaluronate, glycerol, Dipotassium glycyrrhizinate, 1,3-BDO and NMF-50;B phase raw material includes niacinamide, glycerol caprylate, decoyl hydroximic acid, 1,2- penta Glycol, hexylene glycol and choline salicylate;
As follows prepared by step:
S1, A phase raw material is added to the emulsion pot sterilized: first the water as solvent is added in the emulsion pot, is added The consumption water for preparing raw material weight 2~4% is accounted for, then transparent xanthan gum, AVC and Sodium Hyaluronate are immersed in water completely, it will The emulsion pot is opened homogeneous and is stirred to after being completely dispersed, and the remaining ingredient put into A phase raw material is warming up to 80~90 DEG C, and middling speed is equal Matter 3-5min;20~40min of insulated and stirred;
S2,40 DEG C of addition B phase raw materials are cooled to, stir evenly to obtain the skin care item.
9. the preparation method of the skin care item according to claim 8 containing choline salicylate, it is characterised in that: the step In rapid S1, the middling speed is 400-500rpm.
CN201811592507.5A 2018-12-25 2018-12-25 A kind of skin care item and preparation method thereof containing choline salicylate Pending CN109602626A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811592507.5A CN109602626A (en) 2018-12-25 2018-12-25 A kind of skin care item and preparation method thereof containing choline salicylate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811592507.5A CN109602626A (en) 2018-12-25 2018-12-25 A kind of skin care item and preparation method thereof containing choline salicylate

Publications (1)

Publication Number Publication Date
CN109602626A true CN109602626A (en) 2019-04-12

Family

ID=66012245

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811592507.5A Pending CN109602626A (en) 2018-12-25 2018-12-25 A kind of skin care item and preparation method thereof containing choline salicylate

Country Status (1)

Country Link
CN (1) CN109602626A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110272353A (en) * 2019-06-14 2019-09-24 珠海萱嘉君行健康产业发展有限公司 A kind of azalaic acid capsaicine ion salt and the preparation method and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101543546A (en) * 2008-03-28 2009-09-30 上海安普生物科技有限公司 Antioxidative substance and composition and use thereof
CN102871863A (en) * 2012-10-24 2013-01-16 成都瑞商通银日用品有限公司 Whitening and water replenishing complex
CN106473935A (en) * 2016-11-08 2017-03-08 宁夏艾伊生物工程研发有限公司 A kind of moisturizer and preparation method thereof
CN107184486A (en) * 2017-07-06 2017-09-22 曾万祥 A kind of facial mask liquid and the facial mask containing the facial mask liquid
CN107753379A (en) * 2017-12-05 2018-03-06 佛山微赢电子商务有限公司 It is a kind of effectively anti-acne to desalinate Whelk-eliminating paste of pockmark and preparation method thereof simultaneously

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101543546A (en) * 2008-03-28 2009-09-30 上海安普生物科技有限公司 Antioxidative substance and composition and use thereof
CN102871863A (en) * 2012-10-24 2013-01-16 成都瑞商通银日用品有限公司 Whitening and water replenishing complex
CN106473935A (en) * 2016-11-08 2017-03-08 宁夏艾伊生物工程研发有限公司 A kind of moisturizer and preparation method thereof
CN107184486A (en) * 2017-07-06 2017-09-22 曾万祥 A kind of facial mask liquid and the facial mask containing the facial mask liquid
CN107753379A (en) * 2017-12-05 2018-03-06 佛山微赢电子商务有限公司 It is a kind of effectively anti-acne to desalinate Whelk-eliminating paste of pockmark and preparation method thereof simultaneously

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
唐倩等: "《药物分析》", 31 January 2017, 中国医药科技出版 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110272353A (en) * 2019-06-14 2019-09-24 珠海萱嘉君行健康产业发展有限公司 A kind of azalaic acid capsaicine ion salt and the preparation method and application thereof

Similar Documents

Publication Publication Date Title
CN110327261A (en) A kind of compact skin skin care compositions and preparation method thereof
JP6089152B2 (en) Exfoliating hair retention promoting formulation
KR102227355B1 (en) Complex cosmetic composition for non-irritating weak acid exfoliation and epithelial cell nutrition
KR101932839B1 (en) A cosmetic composition having excellent skin exfoliation and wrinkle improvement
CN109260116A (en) It is a kind of containing plant extracts to peptide skin base solution and its production technology
JP2001163754A (en) Anti-aging agent and cosmetic formulated therewith
JP2006137744A (en) Prevention or improvement of wrinkles by adam activity-inhibiting substance
JP2001288032A (en) Active oxygen-eliminating agent and skin cosmetic for preventing aging
CN101547939A (en) Propylene glycol hyaluronate ester and external preparation for skin using the same
JPH10298136A (en) New salicylic acid derivative, its use in cosmetic and/or skin composition
KR101797043B1 (en) Manufacturing method of the Natural cosmetics with excellent cleansing and moisturizing effect
JP2004284988A (en) Hair cosmetic and method for inhibiting carbonylation of hair protein
CN110623949A (en) A composition containing azelaic acid monometal salt and Monoxazone for whitening and refining skin, and its preparation method
JP2009256223A (en) Extract liquid from egg of sturgeon
CN109602626A (en) A kind of skin care item and preparation method thereof containing choline salicylate
CN106413681A (en) Ceramide-formulated external agent composition
JP2000229835A (en) Cosmetic material for improving dullness
JPH1029927A (en) Antiaging agent
JP2011195539A (en) Elastase activity inhibitor
CN105997609B (en) A kind of moisture-keeping composition and preparation method thereof
JP2694756B2 (en) Cosmetics containing divalent and trivalent iron salts
CA2643784A1 (en) Personal care compositions comprising ionic liquids
KR20190072013A (en) A cosmetic composition having excellent skin cooling with skin moisturizing effect
CN116546966A (en) Method for producing a cosmetic composition comprising sucrose esters and a solvent
JP2021004237A (en) Topical compositions containing n-acyl dipeptide derivatives and glycolic acid

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190412