CN109588568B - Method for improving reproductive performance of sows by adding procyanidine into daily ration - Google Patents
Method for improving reproductive performance of sows by adding procyanidine into daily ration Download PDFInfo
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- 230000001850 reproductive effect Effects 0.000 title claims abstract description 16
- 238000000034 method Methods 0.000 title claims abstract description 13
- 230000012173 estrus Effects 0.000 claims abstract description 14
- 230000006651 lactation Effects 0.000 claims abstract description 13
- CWEZAWNPTYBADX-UHFFFAOYSA-N Procyanidin Natural products OC1C(OC2C(O)C(Oc3c2c(O)cc(O)c3C4C(O)C(Oc5cc(O)cc(O)c45)c6ccc(O)c(O)c6)c7ccc(O)c(O)c7)c8c(O)cc(O)cc8OC1c9ccc(O)c(O)c9 CWEZAWNPTYBADX-UHFFFAOYSA-N 0.000 claims description 24
- 229920002414 procyanidin Polymers 0.000 claims description 24
- XFZJEEAOWLFHDH-UHFFFAOYSA-N (2R,2'R,3R,3'R,4R)-3,3',4',5,7-Pentahydroxyflavan(48)-3,3',4',5,7-pentahydroxyflavan Natural products C=12OC(C=3C=C(O)C(O)=CC=3)C(O)CC2=C(O)C=C(O)C=1C(C1=C(O)C=C(O)C=C1O1)C(O)C1C1=CC=C(O)C(O)=C1 XFZJEEAOWLFHDH-UHFFFAOYSA-N 0.000 claims description 15
- MOJZMWJRUKIQGL-FWCKPOPSSA-N Procyanidin C2 Natural products O[C@@H]1[C@@H](c2cc(O)c(O)cc2)Oc2c([C@H]3[C@H](O)[C@@H](c4cc(O)c(O)cc4)Oc4c3c(O)cc(O)c4)c(O)cc(O)c2[C@@H]1c1c(O)cc(O)c2c1O[C@@H]([C@H](O)C2)c1cc(O)c(O)cc1 MOJZMWJRUKIQGL-FWCKPOPSSA-N 0.000 claims description 15
- HGVVOUNEGQIPMS-UHFFFAOYSA-N procyanidin Chemical compound O1C2=CC(O)=CC(O)=C2C(O)C(O)C1(C=1C=C(O)C(O)=CC=1)OC1CC2=C(O)C=C(O)C=C2OC1C1=CC=C(O)C(O)=C1 HGVVOUNEGQIPMS-UHFFFAOYSA-N 0.000 claims description 15
- 235000014590 basal diet Nutrition 0.000 claims description 10
- 238000007796 conventional method Methods 0.000 claims description 8
- 238000004140 cleaning Methods 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 2
- 210000003608 fece Anatomy 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 230000002354 daily effect Effects 0.000 claims 2
- 230000003203 everyday effect Effects 0.000 claims 2
- JPFCOVZKLAXXOE-XBNSMERZSA-N (3r)-2-(3,5-dihydroxy-4-methoxyphenyl)-8-[(2r,3r,4r)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2h-chromen-4-yl]-3,4-dihydro-2h-chromene-3,5,7-triol Chemical compound C1=C(O)C(OC)=C(O)C=C1C1[C@H](O)CC(C(O)=CC(O)=C2[C@H]3C4=C(O)C=C(O)C=C4O[C@@H]([C@@H]3O)C=3C=CC(O)=CC=3)=C2O1 JPFCOVZKLAXXOE-XBNSMERZSA-N 0.000 claims 1
- 229920001991 Proanthocyanidin Polymers 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 238000012360 testing method Methods 0.000 abstract description 25
- 238000005516 engineering process Methods 0.000 abstract description 5
- 230000002411 adverse Effects 0.000 abstract description 3
- 230000006353 environmental stress Effects 0.000 abstract description 3
- 239000003674 animal food additive Substances 0.000 abstract description 2
- 230000000694 effects Effects 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 229930014626 natural product Natural products 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 238000012827 research and development Methods 0.000 description 5
- 238000009423 ventilation Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 206010000210 abortion Diseases 0.000 description 1
- 231100000176 abortion Toxicity 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229920002770 condensed tannin Polymers 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 235000012055 fruits and vegetables Nutrition 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 208000002254 stillbirth Diseases 0.000 description 1
- 231100000537 stillbirth Toxicity 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
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- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Birds (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Abstract
The invention belongs to the field of feed additives, and discloses a method for improving the reproductive performance of sows by adding procyanidine into daily ration. 150-300 mg/day of procyanidine is additionally added into the basic daily ration from the middle and later stages of lactation (2 weeks before weaning) to postweaning estrus (2 weeks after weaning), so that the litter size of sows and the birth weight of piglets can be obviously improved. For a pig farm with low litter size and more adverse environmental stress, the farrowing performance of the sows is remarkably improved by adding procyanidine into the daily ration; for a pig farm with higher farrowing performance, the litter size can still be effectively increased by adding procyanidine into the daily ration. The test cost of the technology is less than 1000 yuan per 100 litters, and the litter size is increased between 35 and 145, so the technology has great popularization and application values in pig farms with excellent and poor litter size.
Description
Technical Field
The invention belongs to the field of feed additives, and particularly relates to a method for improving reproductive performance of sows by adding procyanidine into daily ration.
Background
In pig production, the most important factor determining the production level and economic benefit of a pig farm is the reproductive performance of sows. Due to the change of factors such as environment, feed and management, the sows are subjected to larger environmental stress and are easy to suffer from phenomena such as abortion, stillbirth and mummy in production, so that the litter size of the sows is reduced, and the production efficiency of the pig industry is greatly influenced. Therefore, how to improve the reproductive performance of sows becomes an urgent problem to be solved in pig raising production. Researches show that the reproductive performance of sows can be improved by adding certain functional substances into the feed. However, in the prior art, when functional substances are added, the added substances are too many in types and the effect is not obvious. Procyanidine is a kind of plant polyphenol widely existing in fruits and vegetables, and has the advantages of quick absorption, long half-life, high bioavailability, low toxicity, safety, no residue, low cost, etc. Researchers find that the lactation performance of sows can be improved by adding procyanidine into the feed. However, the prior art has no report on the aspect of improving the reproductive performance of sows by procyanidine.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides a method for improving the reproductive performance of sows by adding procyanidine into daily ration.
The purpose of the invention can be realized by the following technical scheme:
application of procyanidine in improving reproductive performance of sow is provided. The application is that 150-300 mg/day of procyanidine is additionally added into the basic ration of each sow from the middle and later lactation period (2 weeks before weaning) to postweaning estrus (2 weeks after weaning), and preferably 200 mg/day of procyanidine is additionally added into the basic ration of each sow. The proanthocyanidins and the conventional basic ration are uniformly mixed, the feed is fed at 7:00 in the morning, the conventional basic ration is continuously added at 3:00 in the afternoon, the diet is free, and a good air environment in a house is maintained.
Application of procyanidine in preparing feed for improving reproductive performance of sow. The feed is prepared by adding procyanidine to basal ration of sows according to the proportion of 75-150 mg/kg, and preferably 100 mg/kg.
The feed for improving the reproductive performance of sows is prepared by adding procyanidine into basic daily ration, wherein the ratio of the procyanidine to the basic daily ration is 75-150 mg/kg, and preferably 100 mg/kg.
A method for improving reproductive performance of sows comprises the step of adding 150-300 mg/day of procyanidine into basic ration of each sow from the middle and late lactation period (2 weeks before weaning) to the postweaning estrus period (2 weeks after weaning), and preferably additionally adding 200 mg/day of procyanidine into the basic ration of each sow. The method can significantly increase litter size of sow and birth weight of piglet.
The method specifically comprises the following technical parameters:
(1) and (3) during the feeding period of the sow: feeding sow according to conventional method, and continuously feeding from middle and late stage of lactation (2 weeks before weaning) to postweaning estrus (2 weeks after weaning);
(2) feeding amount of procyanidine: continuously adding procyanidine according to the proportion of basal daily ration of sows and the dosage of 150-300 mg (preferably 200mg) of each sow per day; procyanidine is purchased from Tianjin peak natural product research and development limited center (but not limited to, other procyanidine products can also achieve the purpose of the invention), and the appearance traits are as follows when the feed is fed: reddish brown powder with purity more than or equal to 95 percent;
(3) the feeding method comprises the following steps: feeding basal diet to sow by conventional method, wherein each pig is fed 2kg per time. On the basis, procyanidine is added according to the proportion of 150-300 mg/2kg (preferably 200mg/2kg), and the mixture is stirred uniformly. Feeding daily ration containing procyanidin at 7:00 a day in the morning, and continuously adding basic daily ration at 3:00 a afternoon;
(4) site management: manual dung cleaning is carried out in time, air circulation and drying in the house are guaranteed, and a water curtain fan system is adopted to guarantee the proper temperature in the house;
(5) feeding period: starting with procyanidins, feeding was continued for 4 weeks.
The invention has the advantages and beneficial effects that:
for a pig farm with low litter size and more adverse environmental stress, the farrowing performance of the sows is remarkably improved by adding procyanidine into the daily ration; for a pig farm with higher farrowing performance, the litter size can still be effectively increased by adding procyanidine into the daily ration. The test cost of the technology is less than 1000 yuan per 100 litters, and the litter size is increased between 35 and 145, so the technology has great popularization and application values in pig farms with excellent and poor litter size.
Detailed Description
The following examples further describe embodiments of the present invention in detail. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
Example 1
Feeding basal diet to sow by conventional method, wherein each pig is fed 2kg per time. Adding procyanidin into conventional basal ration of sow at a ratio of 100mg/2kg (low dose group), mixing well, and feeding. Feeding at 7:00 in the morning and adding conventional basal diet at 3:00 in the afternoon. Continuously feeding from the middle and late lactation period (2 weeks before weaning) to postweaning estrus period (2 weeks after weaning), and continuously feeding for 4 weeks. The temperature in the house is kept appropriate, ventilation and air exchange are carried out, and cleaning is carried out in time.
Procyanidine is purchased from the limited center of research and development of Tianjin peak natural products, and the appearance characters during feeding are as follows: reddish brown powder with purity not less than 95%.
Example 2
Feeding basal diet to sow by conventional method, wherein each pig is fed 2kg per time. Adding procyanidin into conventional basal ration of sow at a ratio of 200mg/2kg (high dose group), mixing well, and feeding. Feeding at 7:00 in the morning and adding conventional basal diet at 3:00 in the afternoon. Continuously feeding from the middle and late lactation period (2 weeks before weaning) to postweaning estrus period (2 weeks after weaning), and continuously feeding for 4 weeks. The temperature in the house is kept appropriate, ventilation and air exchange are carried out, and cleaning is carried out in time.
Procyanidine is purchased from the limited center of research and development of Tianjin peak natural products, and the appearance characters during feeding are as follows: reddish brown powder with purity not less than 95%.
Example 3
Feeding basal diet to sow by conventional method, wherein each pig is fed 2kg per time. Adding procyanidin 150mg/2kg into conventional basal ration of sow, mixing well, and feeding. Feeding at 7:00 in the morning and adding conventional basal diet at 3:00 in the afternoon. Continuously feeding from the middle and late lactation period (2 weeks before weaning) to postweaning estrus period (2 weeks after weaning), and continuously feeding for 4 weeks. The temperature in the house is kept appropriate, ventilation and air exchange are carried out, and cleaning is carried out in time.
Procyanidine is purchased from the limited center of research and development of Tianjin peak natural products, and the appearance characters during feeding are as follows: reddish brown powder with purity not less than 95%.
Example 4
Feeding basal diet to sow by conventional method, wherein each pig is fed 2kg per time. Adding procyanidine into conventional basal ration of sow at a ratio of 300mg/2kg, mixing well, and feeding. Feeding at 7:00 in the morning and adding conventional basal diet at 3:00 in the afternoon. Continuously feeding from the middle and late lactation period (2 weeks before weaning) to postweaning estrus period (2 weeks after weaning), and continuously feeding for 4 weeks. The temperature in the house is kept appropriate, ventilation and air exchange are carried out, and cleaning is carried out in time.
Procyanidine is purchased from the limited center of research and development of Tianjin peak natural products, and the appearance characters during feeding are as follows: reddish brown powder with purity not less than 95%.
Test examples
The effective effect is further clarified below by referring to the test examples.
Test example 1
The test selects the grown-up hybrid sow which is most widely used in production as a test animal, and a daily feed procyanidin adding test is carried out in a large-scale breeding farm. A3 rd sow with 278 th growth is selected, and the influence of 2 kinds of sow daily rations containing procyanidine with different doses prepared in the above embodiments 1-2 of the invention and the daily ration of a control group on the litter size of the sow and the birth weight of piglets is compared and tested. Procyanidin feeding is carried out for 4 weeks from 2 weeks before weaning to the end of oestrus after weaning. The control group contained 93 sows, and used conventional sow feed without procyanidins. The low dose group contained 89 sows, to which procyanidins was added at a rate of 100mg/2kg to the basal ration of sows. The high dose group contained 96 sows, to which procyanidins was added at a rate of 200mg/2kg to the basal ration of sows.
Table 1 effect of procyanidin addition on litter size of sows (test one)
| Group of | Type of sow | Number of births | Nest number | Litter size (head) |
| Low dose group | Grown hybrid | 3 | 89 | 10.65±3.25B |
| High dose group | Grown hybrid | 3 | 96 | 12.10±2.24A |
| Control group | Grown hybrid | 3 | 93 | 10.64±3.24B |
Table 2 effect of procyanidin addition on birth weight of sows and piglets (test one)
| Group of | Type of sow | Number of births | Nest number | Average initial weight (Kg) |
| Low dose group | Grown hybrid | 3 | 89 | 1.52±0.19B |
| High dose group | Grown hybrid | 3 | 96 | 1.65±0.20A |
| Control group | Grown hybrid | 3 | 93 | 1.50±0.19B |
The test results in tables 1 and 2 show that the litter size of the sows in the group with high dosage of daily ration added with procyanidin is obviously improved, the total litter size is improved by 1.45 compared with the control group, and the birth weight is also obviously higher than that of the control group.
Test example 2
The test selects the grown-up hybrid sow as a test animal, and a daily feed procyanidin adding test is carried out in another large-scale breeding farm. The 4 th sow and 303 th sow are selected, and the influence of the daily ration of the sow containing procyanidine prepared in the embodiment 2 of the invention and the daily ration of the control group on the litter size of the sow and the birth weight of the piglet is compared and tested. Procyanidin feeding is carried out for 4 weeks from 2 weeks before weaning to the end of oestrus after weaning. The control group contained 148 sows, with conventional sow feed, without procyanidins. The test group contained 155 sows, to which procyanidins was added at a rate of 200mg/2kg to the basal ration of the sows.
Table 3 effect of procyanidin addition on litter size of sows (trial two)
| Group of | Type of sow | Number of births | Nest number | Gross litter size (head) | Living boy number (head) |
| Test group | Grown hybrid | 4 | 155 | 14.36±3.39 | 13.53±3.12 |
| Control group | Grown hybrid | 4 | 148 | 14.01±3.00 | 13.21±2.86 |
Table 4 effect of procyanidin addition on birth weight of sows and piglets (test two)
| Group of | Type of sow | Number of births | Nest number | Average initial weight (Kg) |
| Test group | Grown hybrid | 4 | 155 | 1.28±0.19 |
| Control group | Grown hybrid | 4 | 148 | 1.30±0.23 |
The experimental results in tables 3 and 4 show that the total litter size of the added group is improved by 0.35 per litter on average, and the birth weight test group has no significant difference from the control group.
Both the test example 1 and the test example 2 find that the number born of the sow is improved by adding the procyanidine, but the improvement range is greatly different, and deep analysis finds that the average number born of the control group sow in the test example 1 is less than 11 and lower than the number born of the 3 rd farrowing sow, and the procyanidine has very remarkable improvement on the farrowing performance of the sow in a pig farm with lower number born and possibly more environmental adverse stress; the average litter size of control group sows in test example 2 was as high as 14, and for this high performance pig farm procyanidins still increased litter size by 0.35/litter. The test cost is less than 1000 yuan per 100 litters, and the litter size is increased between 35 and 145, so the technology has popularization and application values in pig farms with excellent and poor litter size.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.
Claims (8)
1. Application of procyanidine in improving reproductive performance of sow is provided.
2. The use as claimed in claim 1, wherein proanthocyanidin is additionally added in an amount of 150-300 mg/day to the basal diet of each sow from the middle and late lactation period to the postweaning estrus.
3. The use as claimed in claim 2, wherein an additional 200 mg/day of procyanidins is added to the basal ration of each sow from the mid-late lactation period to the post weaning estrus.
4. Application of procyanidine in preparing feed for improving reproductive performance of sow.
5. The use as claimed in claim 4, wherein the feed is prepared by adding procyanidin 75-150 mg/kg into basal ration of sow.
6. The use as claimed in claim 5, wherein the feed is prepared by adding procyanidin at a ratio of 100mg/kg to basal ration of sows.
7. A method for improving the reproductive performance of sows is characterized in that: and adding 150-300 mg/day of procyanidine into the basal ration of each sow from the middle and late lactation period to the postweaning estrus period.
8. The method of claim 7, wherein: the method specifically comprises the following steps:
(1) and (3) during the feeding period of the sow: feeding sows according to a conventional method, and then continuously feeding the sows from the middle and late lactation period to postweaning estrus;
(2) feeding amount of procyanidine: continuously adding procyanidine according to the proportion of basal daily ration of sows and the dosage of 150-300 mg of each sow every day;
(3) the feeding method comprises the following steps: feeding basal ration to sows by a conventional method, feeding 2kg of basal ration to each pig, adding procyanidine according to the proportion of 150-300 mg/2kg on the basis, uniformly stirring, feeding the daily ration containing procyanidine 7:00 in the morning every day, and continuously adding the basal ration 3:00 in the afternoon;
(4) site management: manual dung cleaning is carried out in time, air circulation and drying in the house are guaranteed, and a water curtain fan system is adopted to guarantee the proper temperature in the house;
(5) feeding period: starting with procyanidins, feeding was continued for 4 weeks.
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| WO2000047002A1 (en) * | 1999-02-05 | 2000-08-10 | Siemens Aktiengesellschaft | Method for improving a load distribution in a signalling network |
| DK200201749A (en) * | 2002-11-13 | 2004-05-14 | Nor Feed As | Natural intestinal functional additive for feed or drinking water |
| RU2247577C2 (en) * | 2002-12-20 | 2005-03-10 | Всероссийский научно-исследовательский ветеринарный институт | Vaccine for specific prophylaxis of porcine chlamydiosis |
| DE102009027696A1 (en) * | 2009-07-14 | 2011-02-10 | Westfälische-Wilhelms Universität Münster | Use of proanthocyanidins for the preparation of an anti-adhesive preparation |
| CN101914524B (en) * | 2010-07-23 | 2011-12-21 | 南京农业大学 | Method for extracting microRNA precursor cDNA from cDNA library synthesized from small RNA |
| CN102093748B (en) * | 2011-01-17 | 2013-10-23 | 重庆海巨农业发展有限公司 | Method for preparing radish red pigment homopolymer and radish proanthocyanidin from red-core radishes |
| EP2756765B1 (en) * | 2013-01-17 | 2019-03-27 | Symrise AG | Pharmaceutical compositions |
| AT516221A1 (en) * | 2014-09-04 | 2016-03-15 | Alvetra & Werfft Animal Nutrition Gmbh | Alvecard |
| CN104543404A (en) * | 2015-01-17 | 2015-04-29 | 东北农业大学 | Natural compound feed additive for removing veterinary drug residues |
| CN104705532A (en) * | 2015-04-12 | 2015-06-17 | 中国海洋大学 | Feed additive for improving anti-stress capability of large yellow croakers |
| CN104982723B (en) * | 2015-06-29 | 2018-09-07 | 漳州傲农牧业科技有限公司 | It is a kind of remove sow interior free yl pre-mixing agent and application |
| CN105146089A (en) * | 2015-09-15 | 2015-12-16 | 安徽赛澳生物工程有限公司 | Compound premix for piglet synthetic milk |
| CN105199425A (en) * | 2015-10-12 | 2015-12-30 | 南京农业大学 | Extraction method of cyanidin |
| CN105853406B (en) * | 2016-03-18 | 2020-01-21 | 华南农业大学 | Application of procyanidine in preparation of medicine for preventing and treating porcine reproductive and respiratory syndrome |
| CN105851628A (en) * | 2016-04-18 | 2016-08-17 | 安徽旺旺禽业科技有限公司 | Summer summer-heat clearing and cooling feed for laying hens and preparation method thereof |
| CN107173599A (en) * | 2017-06-15 | 2017-09-19 | 漳州傲农牧业科技有限公司 | A kind of feed addictive for mitigating weaned piglet syndrome and preparation method and application |
| CN107267627B (en) * | 2017-07-12 | 2021-04-20 | 南京农业大学 | Preparation and application of Six1 gene molecular marker related to pig production traits |
| CN107348168A (en) * | 2017-08-25 | 2017-11-17 | 南昌傲农生物科技有限公司 | A kind of feed addictive for improving sow colostrum quality and preparation method and application |
| MX2020013484A (en) * | 2018-06-11 | 2021-05-27 | Ceva Sante Animale | Vaccination against porcine circoviruses. |
| CN113317270B (en) * | 2020-12-25 | 2022-10-25 | 福建傲芯种业科技集团有限公司 | Feeding management method for improving production performance of ternary sows |
| CN113729122B (en) * | 2021-09-03 | 2023-07-25 | 邦基（山东）农业科技有限公司 | Feed capable of improving reproductive performance of sow production and preparation method thereof |
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