CN109549984A

CN109549984A - It is a kind of for treating infertile Chinese medicine composition

Info

Publication number: CN109549984A
Application number: CN201910041775.6A
Authority: CN
Inventors: 田景永
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-01-16
Filing date: 2019-01-16
Publication date: 2019-04-02
Anticipated expiration: 2039-01-16
Also published as: CN109549984B

Abstract

A kind of to belong to technical field of Chinese medicine for treating infertile Chinese medicine composition, with Radix Codonopsis, Herba Cistanches, sargentodoxa cuneata, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba, radix rehmanniae preparata, the root bark of tree peony, ramulus cinnamomi, Medicated Leaven are raw material compatible use；The beneficial effect is that Radix Codonopsis, Herba Cistanches, three medicine of sargentodoxa cuneata are shared as monarch drug in a prescription, it can be with replenishing qi and blood, warm kidney sun, qualcomm meridian；Using Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba, radix rehmanniae preparata as ministerial drug, as square foundation of enriching blood；Using ramulus cinnamomi and the root bark of tree peony as adjutant, ramulus cinnamomi principal drug assistance promoting menstruation is warded off the cold, and the root bark of tree peony mitigates the damp and hot of the dry property of all medicine warms and the lower coke of clear benefit；Using Medicated Leaven as medicine is made, to strengthening the spleen and stomach, promote drug absorption；All medicines share, the effect of playing nourishing qi and blood, clearing and activating the channels and collaterals, warming kidney for dispelling cold, clearing away the damp-heat from the lower-jiao altogether；And drug relevant to prominent disease is prepared, it is particularly suitable for infertility caused by the reasons such as insufficiency of vital energy and blood, kidney qi virtual loss, damp-heat in lower-JIAO, is suitble to mass production and popularization and application.

Description

It is a kind of for treating infertile Chinese medicine composition

Technical field

The invention belongs to technical field of Chinese medicine, and in particular to a kind of for treating infertile Chinese medicine composition.

Background technique

Medically, generally by the Mr. and Mrs of childbearing age 1 year or more the person that do not become pregnant, referred to as infertility after marriage.It is clinical Upper there are three types of situations: 1. having normal sexuality without contraception 1 year, gestation person is not known as infertility；2. do not practise contraception within 1 year after marriage and from Gestation person is not known as primary sterility；3. once there is the pregnant continuous 1 year infertile person that do not practise contraception then to be known as secondary infertility.

It is many that infertile method is treated at present, mainly divides western medical treatment and Chinese traditional treatment.Western medical treatment is controlled with drug Based on treatment and operative treatment, drug therapy mainly improves hormonal readiness, is easy to cause endocrine disorder, leads to other diseases, make With antibiotic treatment genital disease, long-time, large dosage are easy to cause flora imbalance, damage liver kidney function using antibiotic Can, and many antibiosis are known as and cause fetal anomaly drawback.And many patients not can effectively solve problem through western modern medicine treatment.Hand Art treatment mainly artificial impregnation, test-tube baby, but only carry out at present in large hospital few in number, and expense is high, Inconvenience and heavy burden economically are brought to patient home.

In terms of traditional Chinese medicine, according to the viewpoint of motherland's medicine: it is infertile belong to " kidney deficiency " scope, kidney be it is congenital it This, store essential substances.Main reproductive development, native endowment is insufficient, the factors such as daily life day after tomorrow imbalance, overworked, emotional discomfort, excess of sexual intercourse,indulgence in sexual activities Kidney qi is damaged, leads to male's deficiency of kidney-essence, it is infertile basic pathogenesis that deficiency is appointed in women punching, a uterus dystrophy, kidney and the heart, The dirty relationship of liver two is the closest, and Clinical pathology is often the diseases such as kidney deficiency and liver, breakdown of the normal physiological coordination between the heart and the kidney, therefore infertile treatment Using the yang blood and qi for improving the heart, liver, kidney as principle, QI invigorating, blood-nourishing, enriching yin, establishing-Yang are given according to the inclined Sheng of negative and positive of qi and blood respectively Deng, and prescription is carried out with this.As patent document CN 103272162A disclose it is a kind of treat infertile Chinese medicine composition and Preparation method, by motherwort, Radix Codonopsis, Herba Epimedii, Radix Angelicae Sinensis, Rehmannia glutinosa, dried orange peel, the root of three-nerved spicebush, Radix Astragali, Rhizoma Chuanxiong, stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran, Rhizoma Cyperi (vinegar processed), Poria cocos, radix aucklandiae, perilla leaf, donkey-hide gelatin, fructus amomi, radix scutellariae, amber, Radix Glycyrrhizae, agalloch eaglewood, radix cyathulae, fructus lycii promoting the circulation of qi, Effect of invigorating blood circulation carries out beneficial to spirit and marrow, diuresis, kidney-replenishing, nourshing kidney to male, passes through Infertile couples to women progress qi and blood reconciliation Both sides take infertile to treat jointly.Patent document CN 108619441A, which is disclosed, a kind of treats infertile drug Composition and its preparation method and application, by fructus lycii, Semen Cuscutae, ginseng, cortex cinnamomi, fructus alpiniae oxyphyllae, longan, raspberry, excessive The sheep leaves of pulse plants, thizoma curculiginis, Hangzhoupro Morinda offcinalis How are rushed down to carry out bowl spares benefit, and tonifying yin helps sun to carry out tonifying kidney and benefiting sperm, fill up vital essence, are improved kidney essense inadequate natural endowment and are controlled Treatment is controlled infertile.Patent document CN 103989803A discloses a kind of Chinese medicine for treating infertility, using Cortex Eucommiae, meat Osmanthus, raw Radix Astragali, Semen Cuscutae, ginseng, Cortex Magnoliae Officinalis, asarum, Rehmannia glutinosa, licorice consolidate strong member, strengthening vital QI to eliminate pathogenic factors, benefiting qi and raising yang, Nourishing yin and supplementing blood, beneficial to spirit and marrow reinforce the spleen to benefit the lung, Gu tire stopping leak, blood circulation promote to become pregnant.

These drugs are prepared from the angle of kidney tonifying or blood-activating and qi-promoting, are not accounted for systemic reason, are worked as trouble When person only has kidney deficiency or insufficiency of vital energy and blood to cause infertile, these drugs are just effective.But be easy to ignore in this way to waist (kidney it Mansion) disease and genital disease (damp-heat in lower-JIAO) synthesis treatment, therefore many curative effects are not good enough.In fact, most of suffer from Person not only only has part illness, but many reasons synthesis is formed.The kidney being a water ZANG-organ, occupies lower coke, and main water, department open entire, maintenance people Body fluid metabolism, if the gasification of kidney is not normal, fluid metabolism is unbalance, easily initiation damp-heat in lower-JIAO；Waist is house of kidney, modern because Working principle usually sitting, stay up late, lack motion exercise usually, therefore waist tendon and vessel skeletal diseases are generally existing, thus treat When other than it need to consider aforementioned kidney deficiency and qi and blood problem, it must also be noted that recuperate under medical treatment waist disease, tonneau waist channels and collaterals simultaneously, under clear benefit Burnt damp and hot, ability comprehensive treatment in this way obtains good effect.Based on this, the present invention is specifically proposed.

Summary of the invention

Object of the present invention is to the defects of the traditional Chinese medicine for above-mentioned existing treatment infertility, provide a kind of while simultaneous Nourishing qi and blood, clearing and activating the channels and collaterals, warming kidney for dispelling cold, clearing away the damp-heat from the lower-jiao effect are cared for, is lost especially suitable for treatment insufficiency of vital energy and blood, kidney qi Empty, cold-evil illegally occupies, the Chinese medicine composition product of infertility caused by damp-heat in lower-JIAO many reasons are comprehensive, with adapt to it is various not The treatment of pregnant sterility improves infertile success rate.

To achieve the above object, the technical scheme adopted by the invention is that it is a kind of for treating the Chinese medicine group of infertility Close object, it is characterised in that with Radix Codonopsis, Herba Cistanches, sargentodoxa cuneata, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba, radix rehmanniae preparata, the root bark of tree peony, ramulus cinnamomi, Medicated Leaven are original Material compatible use.

Radix Codonopsis strengthening QI of middle-JIAO in side, Herba Cistanches warming and invigorating kidney Yang, benefiting essence-blood, sargentodoxa cuneata is promoting blood circulation and removing obstruction in channels, three medicines share replenishing qi and blood, Warm kidney sun, qualcomm meridian are monarch drug in a prescription altogether；Radix Angelicae Sinensis, Rhizoma Chuanxiong replenishing and activating blood, Radix Paeoniae Alba Yangyin Rougan liver, relieving spasm to stop pain, radix rehmanniae preparata kidney tonifying, essence replenishing, this Four medicines are to enrich blood square foundation Siwu Tang, and all medicines of compatibility are all ministerial drug to augment the function of blood；Ramulus cinnamomi warming meridians and promoting circulation of qi, helps yang transforming qi, both Sargentodoxa cuneata clearing and activating the channels and collaterals can be helped, and cold-evil can be expelled；The root bark of tree peony enters conscience kidney channel, and clearing heat and cooling blood, activating microcirculation and removing stasis medicinal can mitigate all medicines The dry property of warm, but the lower coke of the clear benefit of energy is damp and hot, therefore ramulus cinnamomi and the root bark of tree peony are all adjutant；Medicated Leaven is by polygonum flaccidum, sweet wormwood, Siberian cocklebur Grass, rde bean, semen armeniacae amarae, Chinese patent drug made of wheat bran；Effect with strengthening the spleen and stomach, in the tune that helps digestion；For weakness of the spleen and the stomach, drink Food is stagnated, feeling of stuffiness in chest abdominal distension, infantile indigestion with food retention；Drug induced injury taste can be prevented, and promote drug absorption, to make medicine；All medicines share, The effect of playing nourishing qi and blood, clearing and activating the channels and collaterals, warming kidney for dispelling cold, clearing away the damp-heat from the lower-jiao altogether, to insufficiency of vital energy and blood, kidney qi virtual loss, Han Xiepan It crouches, the treatment of infertility caused by damp-heat in lower-JIAO many reasons has good therapeutic effect.

Concrete scheme is a kind of for treating the Chinese medicine composition of infertility, in terms of mass parts, by following raw material medicaments It is formulated: 30-70 parts of Radix Codonopsis, 15-50 parts of Herba Cistanches, 30-70 parts of sargentodoxa cuneata, 20-50 parts of Radix Angelicae Sinensis, 5-20 parts of Rhizoma Chuanxiong, Radix Paeoniae Alba 10-30 parts, 15-45 parts of radix rehmanniae preparata, 30-80 parts of the root bark of tree peony, 5-20 parts of ramulus cinnamomi, 5-15 parts of Medicated Leaven；It is for general type progestogenic medicine.

Infertility person is generally suffered from, mostly there is comprehensive disease, and mainly show insufficiency of vital energy and blood, damp-heat in lower-JIAO, kidney It is in terms of mass parts, to be formulated by following raw material medicaments that gas virtual loss, cold-evil, which such as illegally occupy at symptoms, the preferred embodiment: 50 parts of Radix Codonopsis, 30 parts of Herba Cistanches, 50 parts of sargentodoxa cuneata, 30 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Paeoniae Alba, 30 parts of radix rehmanniae preparata, 50 parts of the root bark of tree peony, 10 parts of ramulus cinnamomi, 10 parts of Medicated Leaven, be for comprehensive progestogenic medicine.

When insufficiency of vital energy and blood symptom is relatively prominent, Radix Angelicae Sinensis can be added to 5 parts；I.e. bulk pharmaceutical chemicals form are as follows: and 50 parts of Radix Codonopsis, meat 30 parts of desert cistanche, 50 parts of sargentodoxa cuneata, 35 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Paeoniae Alba, 30 parts of radix rehmanniae preparata, 50 parts of the root bark of tree peony, 10 parts of ramulus cinnamomi, six 10 parts of Divine Comedy, be for qi and blood deficiency progestogenic medicine.

Instantly when burnt damp and hot symptom is relatively prominent, the root bark of tree peony can be added to 8 parts；I.e. bulk pharmaceutical chemicals form are as follows: and 50 parts of Radix Codonopsis, meat 30 parts of desert cistanche, 50 parts of sargentodoxa cuneata, 30 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Paeoniae Alba, 30 parts of radix rehmanniae preparata, 58 parts of the root bark of tree peony, 10 parts of ramulus cinnamomi, six 10 parts of Divine Comedy, be for damp-heat type progestogenic medicine.

When kidney qi virtual loss, cold-evil, which illegally occupy symptom, relatively to be protruded, Herba Cistanches can be added to 5 parts, i.e. bulk pharmaceutical chemicals form are as follows: 50 parts of Radix Codonopsis, 35 parts of Herba Cistanches, 50 parts of sargentodoxa cuneata, 30 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Paeoniae Alba, 30 parts of radix rehmanniae preparata, 50 parts of the root bark of tree peony, 10 parts of ramulus cinnamomi, 10 parts of Medicated Leaven, be for asthenic cold type progestogenic medicine.

The product form of Chinese medicine composition can use oral solution, electuary, tablet, capsule, granule, the water-bindered pill, honeyed bolus Etc. dosage forms.

Wherein oral solution is made with the following method.

Raw materials of traditional Chinese medicinal materials is weighed according to the proportion, and 6-10 times of water water of Chinese medicine total weight is then added and decocts 2-4 times, decocts every time It boils time 1-3 hour, collecting decoction, filters, concentration contains filtrate to get oral solution of the present invention is arrived according to every bottle 100ml Product.

Wherein electuary is made with the following method.

Raw materials of traditional Chinese medicinal materials is weighed according to the proportion, and 6-10 times of water water of Chinese medicine total weight is then added and decocts 1-3 times, decocts every time It boils time 1-3 hour, collecting decoction, filters, concentration dry, pulverize, and is sieved, the following powder of 100 mesh is obtained, according to every parcel 6 It gram is dispensed to get electuary product of the present invention.

Wherein honeyed bolus is made with the following method.

Traditional Chinese medicinal material raw materials are weighed according to the proportion, are then milled respectively, is sieved, obtains the following powder of 100 mesh, are remixed It is even, then by etc. quality honey mixed and stirred with mixed-powder, rubbing, pill are made into honeyed bolus, are dispensed for 12 grams according to every parcel, i.e., Obtain honeyed bolus product of the present invention.

Or powder and medically acceptable carrier and/or excipient are made into capsule, tablet, granule or pill etc..

The various dosage forms of above-mentioned Chinese medicine composition of the invention are oral preparations, for treating caused by many reasons not Pregnant sterility needs couple while taking.

By taking oral solution as an example, oral dose is 100ml/ times, i.e. a bottle every time, 4 times/day, one course for the treatment of of two weeks；With punching For agent: oral granule dosage is 6 grams/times, i.e. a parcel every time, and 4 times/day, boiled water rushes soup, warm water drink-service, two weeks i.e. 15 Its course for the treatment of.Oral honeyed bolus metering is 12 grams/times, i.e. a parcel every time, and 4 times/day, warm water takes, one course for the treatment of of two weeks.Medication Period forbids having sexual intercourse, and avoids fatigue.Because of individual difference, medication time is different in size, can become pregnant after usually taking medicine 2-8 months.

In actual therapeutic, generally first according to the different symptoms of couple with corresponding drug is taken, such as side's qi and blood Deficiency when another party's damp-heat in lower-JIAO, first matches convinced blood deficiency type progestogenic medicine and lower warmer wetness-heat type progestogenic medicine, when improving one section respectively Between after again with taking comprehensive progestogenic medicine；Or one side's damp-heat in lower-JIAO first match respectively when another party's kidney qi virtual loss, cold-evil illegally occupy Damp-heat type progestogenic medicine and asthenic cold type progestogenic medicine are taken, takes comprehensive progestogenic medicine again after improving a period of time；Or side's qi and blood When deficiency, another party's kidney qi virtual loss, cold-evil illegally occupy, qi and blood deficiency progestogenic medicine and asthenic cold type progestogenic medicine are first taken respectively, are improved Comprehensive progestogenic medicine is taken after a period of time again；Drug can also be made into Chinese patent drug component as a result, the Chinese patent drug component by Qi and blood deficiency progestogenic medicine 1-3 course for the treatment of dose, damp-heat type progestogenic medicine 1-3 course for the treatment of dose, asthenic cold type progestogenic medicine 1-3 course for the treatment of dose and Comprehensive progestogenic medicine 1-5 course for the treatment of dose is composed.

Among the above, the course for the treatment of dose is metering and time allocation unit.When taking oral solution progestogenic medicine, a course for the treatment of Dose refers to: 4 times a day, each 100ml, the dose of two weeks；That is 60 bottle oral solutions.When taking honeyed bolus progestogenic medicine, one Course for the treatment of dose refers to: 4 times a day, 12 grams every time, the dose of two weeks；That is 720 grams of honeyed bolus.When taking electuary progestogenic medicine, one Course for the treatment of dose refers to: 4 times a day, 6 grams every time, the dose of two weeks；That is 360 grams of electuaries.The course for the treatment of dose of other dosage forms can refer to It executes.

It, can be with replenishing qi and blood, warm kidney the beneficial effects of the invention are as follows sharing Radix Codonopsis, Herba Cistanches, three medicine of sargentodoxa cuneata for monarch drug in a prescription Sun, qualcomm meridian；Using Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba, radix rehmanniae preparata as ministerial drug, as square foundation of enriching blood；Using ramulus cinnamomi and the root bark of tree peony as adjutant, Coke is damp and hot under ramulus cinnamomi principal drug assistance promoting menstruation cold extermination, the dry property of all medicine warms of root bark of tree peony mitigation and clear benefit；Using Medicated Leaven as medicine is made, use With strengthening the spleen and stomach, promote drug absorption；All medicines share plays nourishing qi and blood, clearing and activating the channels and collaterals, warming kidney for dispelling cold, clearing away the damp-heat from the lower-jiao altogether The effect of, the Chinese medicine composition reasonable recipe, treating both manifestation and root cause of disease is significant in efficacy, cheap, to caused by multiclass reason it is infertile not Good therapeutic effect is given birth to, is particularly suitable for infertile caused by the reasons such as insufficiency of vital energy and blood, kidney qi virtual loss, damp-heat in lower-JIAO Disease, and drug relevant to prominent disease is prepared, this product is convenient to take, is suitble to mass production and popularization and application.

Specific embodiment

Below with reference to embodiment, the invention will be further described, and following embodiment is intended to illustrate invention rather than to this Further limiting for invention, should not be limited the scope of the invention with this.

Embodiment 1.

It makes a kind of for treating the Chinese medicine powder electuary of infertility, takes Radix Codonopsis 30kg, Herba Cistanches 15kg, Sargentodoxa cuneata 30kg, Radix Angelicae Sinensis 20kg, Rhizoma Chuanxiong 5kg, Radix Paeoniae Alba 10kg, radix rehmanniae preparata 15kg, root bark of tree peony 30kg, ramulus cinnamomi 5kg, Medicated Leaven 5kg；It is added 10 times of amounts are 1650kg clear water, are impregnated 30 minutes first, then high fire boils, then small fire mulling 90-100 minutes, filters to take liquid； The dregs of a decoction are put into 8 times of amounts i.e. 1320kg clear water again, high fire is used small fire mulling 55-65 minutes after boiling, and filters to take liquid；Again will The dregs of a decoction are put into 6 times of amounts i.e. 990kg clear water, and high fire is used small fire mulling 30-35 minutes after boiling, and filter to take liquid；Merge three times Decoction liquor is concentrated, dry, then crushes, and sieves with 100 mesh sieve, obtains powder, powder is dispensed according to 6 grams of every parcel to get arriving Pulvis electuary product general type progestogenic medicine.

[usage and dosage]: 4 times a day, 6 grams every time, boiled water brews, and warm water takes, and front and back half an hour of having a meal takes, 30 days as one therapeutic course.

[adaptation range]: various infertilities.

[points for attention]: hypertension, hyperglycemic patients are used with caution, heart disease or severe hypertension, diabetic's disabling.

[taboo]: duration of medication forbids having sexual intercourse, and avoids fatigue.

Because of individual difference, medication time is different in size, can become pregnant after usually taking medicine 2-8 months.

Embodiment 2.

Make it is a kind of suitable for insufficiency of vital energy and blood, damp-heat in lower-JIAO, kidney qi virtual loss, cold-evil illegally occupy etc. symptom complexs for treating The Chinese medicine composition oral solution of infertility takes Radix Codonopsis 10kg, Herba Cistanches 6kg, sargentodoxa cuneata 10kg after being exposed to the sun drying, Radix Angelicae Sinensis 6kg, Rhizoma Chuanxiong 2kg, Radix Paeoniae Alba 4kg, radix rehmanniae preparata 6kg, root bark of tree peony 10kg, ramulus cinnamomi 2kg, Medicated Leaven 2kg；Fine powder is broken into pulverizer respectively, It sieves with 100 mesh sieve, is then uniformly mixed, obtain mixed powder, it is spare.The honey of 1.3-1.5 times of mixed powder total weight is taken, this takes Then 80kg honey carries out refined honey, i.e., honey is endured boiling with high fire, then endured slowly with small fire 25-30 minutes, and be heated to 116 DEG C ~118 DEG C, be in light red gloss to foam, hand twists toughness, but cannot pull into long Bai Sishi, while dripping honey cool Refined honey is become when can drop into a bead in water；At this moment refined honey 65.5kg is obtained, boiled refined honey is poured into medicinal powder, and with stirring Device is mixed quickly to stir, while the while of falling honey tune mix medicinal powder, continue when being substantially not visible dry medicinal powder stirring 10-20 minutes；Then It is twisted into fine strip shape, is cut into thin segment, a ball is made, every 0.25-0.35 grams of thin ball is made in this place, by thin ball according to every parcel 12 It gram is dispensed to get comprehensive to the honeyed bolus product for being suitble to insufficiency of vital energy and blood, damp-heat in lower-JIAO, kidney qi virtual loss, cold-evil the symptoms such as to illegally occupy Type progestogenic medicine.

[usage and dosage]: 4 times a day, each 10g, front and back half an hour of having a meal takes, and two weeks is as a treatment course.

[adaptation range]: various infertilities.

Embodiment 3.

A kind of Chinese medicine composition oral solution for being used to treat infertility for biasing toward insufficiency of vital energy and blood symptom is made, in reality It applies and Radix Angelicae Sinensis is increased into 5kg on the basis of example 2.Take Radix Codonopsis 50kg, Herba Cistanches 30kg, sargentodoxa cuneata 50kg, Radix Angelicae Sinensis 35kg, Rhizoma Chuanxiong 10kg, Radix Paeoniae Alba 20kg, radix rehmanniae preparata 30kg, root bark of tree peony 50kg, ramulus cinnamomi 10kg, Medicated Leaven 10kg；10 times of bulk pharmaceutical chemicals total weight amounts are added Clear water, i.e. addition 2950kg clear water, impregnate 40 minutes, then high fire boils, then small fire mulling 90-100 minutes, filters to take first Liquid；The dregs of a decoction are put into 8 times of amounts i.e. 2360kg clear water again, high fire is used small fire mulling 55-65 minutes after boiling, and filters to take liquid； The dregs of a decoction are put into 6 times of amounts i.e. 1770kg clear water again, high fire is used small fire mulling 30-35 minutes after boiling, and filters to take liquid；Merge Medical fluid is concentrated into the weight equal with raw material medicine total weight, i.e. 295kg after leaching liquid by decoction liquor three times, then will be dense Contracting liquid contains to arrive oral solution product qi and blood deficiency progestogenic medicine of the present invention according to every bottle 100ml.

[usage and dosage]: 4 times a day, each 100ml, front and back half an hour of having a meal takes, and two weeks is as a treatment course.

[adaptation range]: various infertilities.

Embodiment 4.

A kind of Chinese medicine composition oral solution for being used to treat infertility for biasing toward damp-heat in lower-JIAO symptom is made, in reality It applies and the root bark of tree peony is increased into 8kg on the basis of example 2.Take Radix Codonopsis 50kg, Herba Cistanches 30kg, sargentodoxa cuneata 50kg, Radix Angelicae Sinensis 30kg, Rhizoma Chuanxiong 10kg, Radix Paeoniae Alba 20kg, radix rehmanniae preparata 30kg, root bark of tree peony 58kg, ramulus cinnamomi 10kg, Medicated Leaven 10kg；10 times of bulk pharmaceutical chemicals total weight amounts are added Clear water, i.e. addition 2980kg clear water, impregnate 40 minutes, then high fire boils, then small fire mulling 90-100 minutes, filters to take first Liquid；The dregs of a decoction are put into 8 times of amounts i.e. 2384kg clear water again, high fire is used small fire mulling 55-65 minutes after boiling, and filters to take liquid； The dregs of a decoction are put into 6 times of amounts i.e. 1788kg clear water again, high fire is used small fire mulling 30-35 minutes after boiling, and filters to take liquid；Merge Medical fluid is concentrated into the weight equal with raw material medicine total weight, i.e. 298kg after leaching liquid by decoction liquor three times, then will be dense Contracting liquid contains according to every bottle 100ml and takes orally liquid product damp-heat type progestogenic medicine to get to the present invention.

[adaptation range]: various infertilities.

Embodiment 5.

Make it is a kind of bias toward kidney qi virtual loss, cold-evil illegally occupy symptom for treating the Chinese medicine composition mouth of infertility Liquid is taken, Herba Cistanches are increased into 5kg on the basis of embodiment 2.Take Radix Codonopsis 50kg, Herba Cistanches 35kg, sargentodoxa cuneata 50kg, Radix Angelicae Sinensis 30kg, Rhizoma Chuanxiong 10kg, Radix Paeoniae Alba 20kg, radix rehmanniae preparata 30kg, root bark of tree peony 50kg, ramulus cinnamomi 10kg, Medicated Leaven 10kg；Bulk pharmaceutical chemicals total weight is added The clear water of 10 times of amounts, i.e. addition 2950kg clear water, impregnate 40 minutes first, and then high fire boils, then small fire mulling 90-100 points Clock filters to take liquid；The dregs of a decoction to be put into 8 times of amounts i.e. 2360kg clear water again, high fire is used small fire mulling 55-65 minutes after boiling, Filter to take liquid；The dregs of a decoction are put into 6 times of amounts i.e. 1770kg clear water again, high fire is used small fire mulling 30-35 minutes after boiling, filtering Take liquid；Merge decoction liquor three times, refilters, be concentrated into the quality such as crude drug, i.e. 295kg, then by concentrate according to every bottle 100ml, which contains, takes orally liquid product asthenic cold type progestogenic medicine to get to the present invention.

[adaptation range]: various infertilities.

Embodiment 6.

It makes a kind of for treating the Chinese medicine powder electuary of infertility, takes Radix Codonopsis 70kg, Herba Cistanches 50kg, Sargentodoxa cuneata 70kg, Radix Angelicae Sinensis 50kg, Rhizoma Chuanxiong 20kg, Radix Paeoniae Alba 30kg, radix rehmanniae preparata 45kg, root bark of tree peony 80kg, ramulus cinnamomi 20kg, Medicated Leaven 15kg； 10 times of amounts i.e. 4500kg clear water is added, impregnates 50 minutes first, then high fire boils, then small fire mulling 90-100 minutes, filtering Take liquid；The dregs of a decoction are put into 8 times of amounts i.e. 3600kg clear water again, high fire is used small fire mulling 55-65 minutes after boiling, and is filtered to take Liquid；The dregs of a decoction are put into 6 times of amounts i.e. 2700kg clear water again, high fire is used small fire mulling 30-35 minutes after boiling, and filters to take liquid； Merge decoction liquor three times, is concentrated, it is dry, then crush, it sieves with 100 mesh sieve, obtains powder, by powder according to 6 grams points of every parcel It fills to get pulvis electuary product general type progestogenic medicine is arrived.

[usage and dosage]: 4 times a day, 6 grams every time, boiled water brews, and warm water takes, and front and back half an hour of having a meal takes, Half a month is as a treatment course.

[adaptation range]: various infertilities.

Clinical observation on the therapeutic effect.

One, case selection.

In January, 2015 ~ 2018 year January is chosen in the infertility patient man and wife of Qianjiang District of Chongqing people's health clinic 122 pairs of examples, the age, male 26-45 years old, women 24-40 years old.

Two, the diagnosis basis of barrenness.

It is diagnosed according to " gynaecology " (national higher medical education teaching material).

(1) have normal sexuality without contraception 1 year not gestation person be known as infertility.

(2) do not practise contraception within 1 year after marriage and never pregnant person is known as primary sterility.

(3) once there is the pregnant continuous 1 year infertile person that do not practise contraception then to be known as secondary infertility.

Three, efficacy assessment standard.

(1) clinical cure: protopathy, normal pregnancy to term birth are corrected.

(2) it is not cured: pregnant not yet by the above drug therapy.

Four, application method: using taking orally, couple take simultaneously, 4 times/day, warmly take, one course for the treatment of of half a month.Monthly first half Moon medication, rear half a month are discontinued, and all patients treat the 2-8 course for the treatment of.In 122 couples of Mr. and Mrs, some are that couple are suffering from not Pregnant disease, some are bridegroom's or husband's side illness, some are wife's side illness, even if being the bridegroom's or husband's side or the state of an illness is individually showed on the wife's side, also need another party Cooperation, therefore in diagnosis and treatment, it is desirable that men and women carry out diagnosis and treatment medication simultaneously；There is taking medicine according to corresponding illness for infertility, does not have There is one side of man and wife for showing infertility to take medicine according to comprehensive illness；Have take relative medicine the early period of corresponding protrusion disease, Comprehensive progestogenic medicine is taken after a period of time.

122 couples of Mr. and Mrs are in totally 244 people, at the same show insufficiency of vital energy and blood, that damp-heat in lower-JIAO, kidney qi virtual loss, cold-evil illegally occupy etc. is comprehensive Mould assembly symptom and a small amount of (8 people) infertility does not have 152 people, takes the honeyed bolus comprehensive progestogenic medicine of the production of embodiment 2. In these patients, insufficiency of vital energy and blood symptom show it is more outstanding have 18 people, take embodiment 3 production oral solution insufficiency of vital energy and blood Type progestogenic medicine.In these patients, damp-heat in lower-JIAO symptom show it is more outstanding have 30 people, take the oral of the production of embodiment 4 Liquid damp-heat type progestogenic medicine.In these patients, kidney qi virtual loss, cold-evil illegally occupy symptom show it is more outstanding have 44 people, take reality Apply the oral solution asthenic cold type progestogenic medicine of the production of example 5.The comprehensive progestogenic medicine of honeyed bolus is taken after the 2-3 course for the treatment of.

Five, points for attention.

Preceding half a month duration of medication forbids having sexual intercourse, and avoids fatigue.Duration of medication, which is avoided, eats raw and cold, greasy, maror, after pregnancy It can deactivate.

Six, treatment results.

By 2-8 months medication treatments, in 122 couples of Mr. and Mrs, there are 149 people to obtain in 152 people with comprehensive symptom It cures, there are 16 people to be cured in 18 people based on insufficiency of vital energy and blood symptom, have 27 in 30 people based on burnt damp and hot symptom below People is cured, and being illegally occupied in 44 people based on symptom with kidney qi virtual loss, cold-evil has 39 people to be cured；Have 112 in these patients To Mr. and Mrs, the successful pregnancies in 8 months, wherein 107 pairs of Mr. and Mrs' term births, success cure rate is up to 87.7%.It see the table below.

Seven, conclusion.

The present invention has apparent therapeutic effect for infertility, and when treatment has no toxic side effect, and medication is convenient, effectively For rate up to 91.8%, cure rate is the choice drug of barrenness patient up to 87.70%.

Eight, typical case.

Patient Zeng Mr. and Mrs, Zeng Mounan, 31 years old, wife Chen, female, 28 years old, both sides were enterprise, factory worker, were often added Class, daily life owe rule, get married more than 5 years, do not take contraceptives after marriage, do not become pregnant always, and once many places medical treatment diagnosis and treatment have no resolution, It is medical to come here through friend's introduction: Zeng tells pain in the loins often, easily tired, especially with obvious, dampness of scrotum when tired and rainy weather, Urine is yellow, and pale tongue, whitish tongue is greasy, deeptensepulse, and the past hospital, which checks, to be prompted: Zeng's lumbar muscle strain, prostatitis, low sperm activity, Diagnosis: kidney-yang deficiency, damp-heat in lower-JIAO；Chen tells easy giddy, and cold limbs, it is poor to sleep, and mood is emotional or low, and menstruation is delayed, Amount is few, and color is light, menstrual period waist abdominal pain, and sleepiness is withered soft, previously checks: pelvic hydrops, adnexitis, anemia.Deep thready pulse, pale tongue tongue fur It is white.Diagnosis: insufficiency of vital energy and blood.Damp-heat type progestogenic medicine is taken to Zeng and takes orally liquid product, while being taken qi and blood deficiency to Chen and being promoted Pregnant medicine takes orally liquid product, and after taking 2 course for the treatment of, Zeng's pain in the loins symptom disappears substantially, suddenly feels tired, and urine color is clear, and Chen is dizzy It disappears, four limbs are warm, are in a cheerful frame of mind, and menstruation returns to normal, and menstrual period waist colic symptoms disappear.Then man and wife takes this simultaneously Successful pregnancies after invention Chinese medicine composition honeyed bolus product 5 courses for the treatment of of comprehensive progestogenic medicine are discontinued, 1 boy baby of term birth.

Patient thanks to certain Mr. and Mrs, thanks certain, and male, 28 years old, wife Zhang, 26 years old, couple were employee, gets married 2 years It is remaining, do not take contraceptives, always unpregnancy, here go to a doctor it is preceding many places diagnosis and treatment have no resolution in the time more than 1 year, it is light to thank to certain private prosecution work Pine, but normal sitting lack movement, and frequent urine is deep yellow, and with burning heat sensation when defecation, hospital checks and shows no obvious abnormalities, slippery Number, red tongue with yellowish and greasy fur, diagnosis: damp-heat in lower-JIAO.Zhang tells that constitution is poor since the childhood, especially cold, timid, and love is had horrible nightmares, nearly 2 years Gastrointestinal function is poor, diet do not pay attention to slightly will diarrhea, once unexpected pregnant history, selects manual termination pregnant because of various reasons before marriage It is pregnent, does not become pregnant again thereafter, hospital checks prompt before: pelvic hydrops 3.6cm, left side tubal occlusion, hormonal readiness are low.Arteries and veins It is weak, pale tongue with white fur.Diagnosis: insufficiency of vital energy and blood, heart-kidney yang deficiency.Damp-heat type progestogenic medicine oral solution is taken to certain is thanked, while being taken to Zhang With qi and blood deficiency progestogenic medicine oral solution, after taking 1 course for the treatment of, thanks to certain urine and restore normal, symptom that Zhang is cold, love is had horrible nightmares It disappears, appetite enhancing does not occur symptom of diarrhea again after medication；Then man and wife takes the traditional chinese medicine composition of the invention honeyed bolus product simultaneously 2 courses for the treatment of of comprehensive progestogenic medicine, successful pregnancies, a son under term birth, after the birth, mother and child were doing well.

Patient Lee Mr. and Mrs, Lee, male, 42 years old, wife Sun, 38 years old, Lee was self-employed worker, wife in working unit, A female has been given birth to, 11 years old, now because of family planning policy adjustment, has given birth to a tire again intentionally, but do not achieve one's goal.Lee operates a business from the cause, It is usually more tired, feel that energy is not good often, waist and knee crymodynia, dizzy tinnitus of suddenly feeling, deep thready pulse, tongue fur is thin white, and diagnosis: liver kidney is not Foot.Sun's cause work sitting often, lacks motion exercise, the frequent stiff pain of neck waist, and often violate urinary tract infections, menstruation Rule is owed, color is black, amount is few, and leukorrhagia Huang is thick peculiar smell, deep thready pulse, red tongue and white coating on the tongue, diagnosis: kidney-yin deficiency, damp-heat in lower-JIAO.Give Lee's clothes Liquid product is taken orally with the traditional chinese medicine composition of the invention asthenic cold type progestogenic medicine, while Sun takes damp-heat type progestogenic medicine and takes orally liquid product, After taking 3 course for the treatment of, Lee feels full of vitality, and waist and knee crymodynia, dizzy tinnitus symptom disappear.The stiff pain of Sun's neck waist is bright Aobvious to improve, menstruation rule, color, matter, amount are normal, and leukorrhea is normal.It then proceedes to take the comprehensive progestogenic of the traditional chinese medicine composition of the invention Medicine honeyed bolus product, man and wife continue 3 courses for the treatment of i.e. successful pregnancies of taking medicine, term birth, after the birth, mother and child were doing well with taking.

Patient poplar Mr. and Mrs, poplar male, 29 years old, wife Zhang, 26 years old, both sides were peasant, in the country by cultivating and selling Non-staple foodstuff job, gets married more than 4 years, and unpregnancy, has no resolution through multi-treatment always, and poplar private prosecution is careless because lifting weight in building site at its 20 years old Waist is damaged, pain in the loins disease is hereafter fallen, causes lower limb distending pain numb when serious, whenever fatigue, Changes in weather, which is easy to induce, to be added Weight, again because failing to give birth to, mood is constrained within nearly 2 years, and gradually problematic in terms of sexual intercourse, hyposexuality, premature ejaculation is obvious, and hospital checks and mentions Show: L5-S1 disc herniation (central type), remaining to show no obvious abnormalities, deep thready pulse, pale tongue with white fur, diagnosis: kidney deficiency and liver, train of thought It is impaired.Zhang limits from cause sanitary conditions, and shortcoming in terms of sex hygiene, frequent frequent micturition, urgent urination, urodynia buy A Moxi by oneself The treatment of woods capsule oral, it is other substantially without discomfort.Diagnosis: damp-heat in lower-JIAO.It gives poplar and takes the traditional chinese medicine composition of the invention asthenic cold type Progestogenic medicine takes orally liquid product, while Zhang takes damp-heat type progestogenic medicine and takes orally liquid product, after taking 3 course for the treatment of, poplar Lumbago Shape disappears, and does not recur again, and compared with being remarkably reinforced before medication, premature ejaculation symptom improves sexual desire；The disappearance of Zhang's urinary tract infections symptom is not recurred. It then proceeding to take the comprehensive progestogenic medicine honeyed bolus product of the traditional chinese medicine composition of the invention, man and wife continues 3 courses for the treatment of of taking medicine with taking, at Function is become pregnant, and a son under term birth, after the birth, mother and child were doing well.

Certain Mr. and Mrs more than patient, it is remaining certain, male, 35 years old, wife thanked certain, and 32 years old, both sides had no regular occupation, get married nearly 10 years, It was once pregnant in the first two years 2 times after marriage, and miscarried in second trimester, do not become pregnant, failed to respond to any medical treatment everywhere again later, debt-ridden, body and mind It is all tired, it suffers untold misery, by the agency of has the phychology having a try in arms and comes to seek advice from.It is remaining certain from the cause without fixed work, life is not advised very much Rule, stays up late often in addition and plays, and often feels the swollen discomfort of lumbosacral region acid, urine jaundice, eyes are dry and astringent, and perineum is moist, and brothers' heart easily goes out Cold sweat, previous check show no obvious abnormalities, and deeptensepulse is powerless, red tongue with yellowish fur, diagnosis: the deficiency of liver-yin and kidney-yin.Certain is thanked to tell, usually constitution compared with Difference is pregnant before to then abortion in 4, May, and in addition not rich, small postpartum fails rehabilitation of sufficiently accomplishing, and often sense is dizzy recently, and four Limb is ice-cold, and tired powerless, loss of appetite, mental state is low, and menstruation is delayed, and the few color of amount is light, and touching more than 10 Japanese side stops, and pulse condition is thin and delicate, Whitish tongue is greasy, diagnosis: insufficiency of vital energy and blood, heart-kidney yang deficiency.Certain takes the production of the traditional chinese medicine composition of the invention asthenic cold type progestogenic medicine oral solution more than giving Product, at the same thank certain take qi and blood deficiency progestogenic medicine take orally liquid product, after taking 5 course for the treatment of, it is remaining certain tell that lumbosacral region acid is swollen, eyes Dry and astringent, perineum is moist, and brothers' heart easily be in a cold sweat symptom disappearance, thank certain tell take medicine after the state of mind it is good, diet increases, dizzy disease Shape disappears, four limbs warm, and menstruation recovery is normal.It then proceedes to take the comprehensive progestogenic medicine honeyed bolus production of the traditional chinese medicine composition of the invention Product, man and wife continue 3 courses for the treatment of of taking medicine, successful pregnancies, term birth, mother and daughter's safety with taking.

Claims

1. a kind of for treating infertile Chinese medicine composition, it is characterised in that be formulated by following raw material medicaments: Radix Codonopsis, meat Desert cistanche, sargentodoxa cuneata, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba, radix rehmanniae preparata, the root bark of tree peony, ramulus cinnamomi, Medicated Leaven；The weight proportion of the bulk pharmaceutical chemicals are as follows: Radix Codonopsis 30-70 parts, 15-50 parts of Herba Cistanches, 30-70 parts of sargentodoxa cuneata, 20-50 parts of Radix Angelicae Sinensis, 5-20 parts of Rhizoma Chuanxiong, 10-30 parts of Radix Paeoniae Alba, radix rehmanniae preparata 15-45 parts, 30-80 parts of the root bark of tree peony, 5-20 parts of ramulus cinnamomi, 5-15 parts of Medicated Leaven.

2. according to claim 2 for treating infertile Chinese medicine composition, it is characterised in that the bulk pharmaceutical chemicals Weight proportion are as follows: 50 parts of Radix Codonopsis, 30 parts of Herba Cistanches, 50 parts of sargentodoxa cuneata, 30 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Paeoniae Alba, radix rehmanniae preparata 30 Part, 50 parts of the root bark of tree peony, 10 parts of ramulus cinnamomi, 10 parts of Medicated Leaven, it is defined as comprehensive progestogenic medicine.

3. according to claim 2 for treating infertile Chinese medicine composition, it is characterised in that the bulk pharmaceutical chemicals Weight proportion are as follows: 50 parts of Radix Codonopsis, 30 parts of Herba Cistanches, 50 parts of sargentodoxa cuneata, 35 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Paeoniae Alba, radix rehmanniae preparata 30 Part, 50 parts of the root bark of tree peony, 10 parts of ramulus cinnamomi, 10 parts of Medicated Leaven, it is defined as qi and blood deficiency progestogenic medicine.

4. according to claim 2 for treating the Chinese medicine composition of infertility, it is characterised in that the bulk pharmaceutical chemicals Weight proportion are as follows: 50 parts of Radix Codonopsis, 30 parts of Herba Cistanches, 50 parts of sargentodoxa cuneata, 30 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Paeoniae Alba, radix rehmanniae preparata 30 Part, 58 parts of the root bark of tree peony, 10 parts of ramulus cinnamomi, 10 parts of Medicated Leaven, it is defined as damp-heat type progestogenic medicine.

5. according to claim 2 for treating the Chinese medicine composition of infertility, it is characterised in that the bulk pharmaceutical chemicals Weight proportion are as follows: 50 parts of Radix Codonopsis, 35 parts of Herba Cistanches, 50 parts of sargentodoxa cuneata, 30 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Paeoniae Alba, radix rehmanniae preparata 30 Part, 5,0 part of the root bark of tree peony, 10 parts of ramulus cinnamomi, 10 parts of Medicated Leaven, it is defined as asthenic cold type progestogenic medicine.

6. according to claim 1 for treating the Chinese medicine composition of infertility described in -5, it is characterised in that the Chinese medicine Composition is Chinese patent drug component, and the Chinese patent drug component is by qi and blood deficiency progestogenic medicine 1-3 course for the treatment of dose, damp-heat type progestogenic medicine 1- 3 course for the treatment of doses, asthenic cold type progestogenic medicine 1-3 course for the treatment of dose and comprehensive progestogenic medicine 1-5 course for the treatment of dose are composed.

7. according to claim 1 for treating the Chinese medicine composition of infertility described in -5, it is characterised in that the Chinese medicine The product form of composition is one of following dosage form: oral solution, electuary, tablet, capsule, granule, pill.

8. according to claim 7 for treating the Chinese medicine composition of infertility, it is characterised in that the oral solution The preparation method is as follows: meter takes each raw material medicine according to the proportion, the clear water of 10 times of raw material medicine total weight amounts are added, impregnate first 30-50 minutes, then high fire boiled, then small fire is micro- boils 90-100 minutes, then filtered to take liquid；The dregs of a decoction are put into bulk pharmaceutical chemicals again In the clear water of 8 times of total weight amounts, high fire is boiled 55-65 minutes after boiling with small fire is micro-, and liquid is then filtered to take；The dregs of a decoction are put into again In the clear water of 6 times of bulk pharmaceutical chemicals total weight amounts, high fire is boiled 30-35 minutes after boiling with small fire is micro-, and liquid is then filtered to take；Merge three times Medical fluid is concentrated into the equal weight of crude drug total weight, then by the medical fluid after concentration according to every after leaching liquid by decoction liquor Bottle 100ml contain to get.