CN109541792B - Slide reading system - Google Patents
Slide reading system Download PDFInfo
- Publication number
- CN109541792B CN109541792B CN201811614906.7A CN201811614906A CN109541792B CN 109541792 B CN109541792 B CN 109541792B CN 201811614906 A CN201811614906 A CN 201811614906A CN 109541792 B CN109541792 B CN 109541792B
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- slide
- glass
- microscope
- shaped
- bottom plate
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- 239000011521 glass Substances 0.000 claims abstract description 93
- 238000011084 recovery Methods 0.000 claims abstract description 40
- 230000007246 mechanism Effects 0.000 claims abstract description 18
- 230000006870 function Effects 0.000 claims abstract description 7
- 238000004064 recycling Methods 0.000 claims description 10
- 230000008093 supporting effect Effects 0.000 claims description 6
- 230000009471 action Effects 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 2
- 230000003321 amplification Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/26—Stages; Adjusting means therefor
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
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- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Microscoopes, Condenser (AREA)
Abstract
The invention discloses a glass slide reading system, which comprises a bottom plate, wherein a microscope for reading glass slide information is arranged on the bottom plate, a mechanical gripper for gripping and conveying glass slides is arranged on the bottom plate positioned on one side of the microscope, a glass slide recovery mechanism with translation and jacking functions is arranged on the bottom plate positioned on the other side of the microscope, and the mechanical gripper horizontally reciprocates between the microscope and the glass slide recovery mechanism. The automatic slide glass sorting device is simple in structure and convenient to use, realizes full-automatic slide glass reading and sorting recovery, improves slide glass reading efficiency, greatly reduces manual work load, realizes standardized and normalized cover sheets of the slide glass, and is convenient to repeatedly review in the later stage.
Description
Technical Field
The invention relates to a slide glass reading technology, in particular to a slide glass reading system.
Background
In the detection field based on pathology, cytology or histology, the information of pathogens, cells or tissues and the like is read mainly by means of the amplification effect of a microscope, so that scientific research data are provided for people. At present, the slide glass is manually read, namely, the slide glass with a specimen is manually placed on an objective table of a microscope, then the sample information is manually read, and the slide glass is manually collected after the slide glass is read. The above-mentioned film reading process has the following problems: firstly, the whole film reading process is low in automation degree, large in manual intervention, pollution risk and problems of manual film reading variability and low film reading efficiency exist, so that the whole film reading process lacks a unified film reading standard; and secondly, the glass slides are directly discarded at the designated positions or manually stacked after being read, so that the workload of stacking the glass slides is large, memory confusion is easy to occur in the stacking process, the difficulty of repeatedly reading the glass slides is large, and the interpretation, teaching and scientific research of results are not facilitated.
Disclosure of Invention
The invention aims to provide a slide glass reading system with high automation degree, which completely avoids manual intervention, realizes standardized and standardized slide glass reading, improves the slide glass reading efficiency, can automatically sort and recycle the slide glass and is convenient for repeated later reference.
In order to achieve the above purpose, the invention adopts the following technical scheme:
The glass slide reading system comprises a bottom plate, wherein a microscope for reading glass slide information is arranged on the bottom plate, a mechanical gripper for gripping and conveying glass slides is arranged on the bottom plate positioned on one side of the microscope, a glass slide recovery mechanism with translation and jacking functions is arranged on the bottom plate positioned on the other side of the microscope, and the mechanical gripper horizontally reciprocates between the microscope and the glass slide recovery mechanism.
The mechanical gripper comprises a transverse guide rail arranged on the bottom plate, a rotating assembly driven by a power source is arranged on the transverse guide rail in a sliding mode, a lifting assembly is arranged on a vertical guide rail of the rotating assembly in a sliding mode, and a pair of clamping arms used for clamping the glass slide are arranged on the lifting assembly.
The rotating assembly comprises a mounting seat which is arranged on the transverse guide rail in a sliding mode, a rotating support driven by a rotating cylinder is arranged on the mounting seat, and the vertical guide rail is arranged on a vertical plate of the rotating support.
The lifting assembly comprises an L-shaped lifting plate which is arranged on the vertical guide rail in a sliding manner, a screw rod stepping motor arranged on the rotating assembly drives the L-shaped lifting plate to lift, a clamping cylinder is arranged on the horizontal portion of the L-shaped lifting plate, two clamping arms are respectively fixedly connected to clamping heads of the clamping cylinder, each clamping arm is of an L-shaped structure, and a limiting clamping groove matched with the glass slide is formed in the horizontal section of each clamping arm along the length direction of each clamping arm.
Slide glass recovery mechanism is including setting up the door font frame on the bottom plate, the roof of door font frame is put up and is equipped with the open-ended recovery box in the end, the symmetry is provided with a pair of support spacing subassembly that prevents that the slide glass from dropping on retrieving the lateral wall of box, and the below of door font frame is equipped with the pushing hands subassembly that has translation and jacking effect through the stand frame, the jacking piece of pushing hands subassembly comes and goes from top to bottom between door font frame and recovery box.
The pushing handle assembly comprises a horizontal plate erected below the door-shaped frame, a pair of recovery guide rails extending transversely are arranged on the horizontal plate, a base driven by a linear air cylinder is arranged on the recovery guide rails in a sliding mode, a lifting air cylinder piston rod below the base extends upwards out of the base, and the jacking block is fixedly connected to the piston rod.
The supporting and limiting assembly comprises a wedge-shaped block hinged to the side wall of the recovery box, and a torsion spring is sleeved on a hinge shaft of the wedge-shaped block.
The recovery box is fixedly connected with the door-shaped frame through a mounting frame sleeved at the bottom of the recovery box.
At least two groups of wedge-shaped limiting blocks are symmetrically arranged on the left edge and the right edge of the jacking block, and inclined planes on the inner sides of the wedge-shaped limiting blocks are matched with the glass slide.
The microscope is a full-automatic microscope.
The slide glass sorting machine has the advantages of simple structure, convenience in use, realization of full-automatic slide glass reading and sorting recovery, improvement of slide glass reading efficiency, great reduction of manual work load, realization of standardized and normalized slide glass, and convenience in later repeated reference. Specifically, the mechanical gripper not only can automatically grip and place the glass slide on the objective table of the microscope, but also can grip and place the glass slide after the glass slide is read on the jacking block, and the full-automatic microscope can automatically read, store and compare sample information, so that later-stage reference is facilitated; the slide glass recovery mechanism is used for orderly stacking the slide glass after the slide glass is read in the recovery box according to the slide glass reading sequence, so that the slide glass recovery mechanism is convenient to find, reduces the repeated slide glass reading difficulty, and provides convenience for fields such as teaching, scientific research and in-vitro detection.
Drawings
Fig. 1 is a schematic structural view of the present invention.
Fig. 2 is a schematic structural view of the mechanical gripper according to the present invention.
FIG. 3 is a schematic view of the slide recovery mechanism of the present invention (omitting a side plate of the portal frame).
Fig. 4 is a schematic structural view of the supporting and limiting assembly according to the present invention.
Fig. 5 is a schematic structural view of the jacking block according to the present invention.
Detailed Description
As shown in fig. 1, the slide glass reading system of the invention comprises a bottom plate 1, wherein a microscope 2 (the microscope 2 is a full-automatic microscope) for reading information of a slide glass 3 is arranged on the bottom plate 1, cell information on the slide glass 3 can be automatically identified, a mechanical gripper for gripping the slide glass 3 is arranged on the bottom plate 1 positioned on one side of the microscope 2, a slide glass recovery mechanism with translation and jacking functions is arranged on the bottom plate 1 positioned on the other side of the microscope 2, and the mechanical gripper horizontally reciprocates between the microscope 2 and the slide glass recovery mechanism and is used for connecting the microscope 2 and the slide glass recovery mechanism, and the slide glass on a stage of the microscope 2 is gripped on the slide glass recovery mechanism.
As shown in fig. 2, the mechanical gripper includes a transverse guide rail 4.1 disposed on the bottom plate 1, a rotating assembly driven by a power source is slidably disposed on the transverse guide rail 4.1, the rotating assembly includes a mounting seat 4.4 slidably disposed on the transverse guide rail 4.1, a rotating bracket 4.5 driven by a rotating cylinder is disposed on the mounting seat 4.4, a lifting assembly is slidably disposed on a vertical guide rail 4.2 on a vertical plate of the rotating bracket 4.5, the lifting assembly includes an L-shaped lifting plate 4.6 slidably disposed on the vertical guide rail 4.2, a screw stepper motor disposed on the lower portion of the rotating bracket 4.5 drives the L-shaped lifting plate 4.6 to lift, a clamping cylinder 4.7 is disposed on a horizontal portion of the L-shaped lifting plate 4.6, a pair of clamping arms 4.3 for clamping the slide glass 3 are disposed on a clamping head of the clamping cylinder 4.7, and the horizontal section of the clamping arm 4.3 is provided with a L-shaped structure along a length direction thereof, and is convenient to be clamped with the slide glass 3 (the slide 3 is clamped on a limit groove). The mechanical gripper has the functions of transverse translation, longitudinal translation, lifting and rotation, the dyed glass slide 3 is gripped and conveyed to the objective table of the microscope 2, the abandoned glass slide 3 is gripped and placed on the jacking block 5.3 of the glass slide recovery mechanism after the reading is completed, the automatic transfer of the glass slide is realized, and the manual glass slide taking and placing is completely avoided.
As shown in fig. 1 and 3-5, the slide glass recycling mechanism comprises a door-shaped frame 5.1 arranged on a bottom plate 1, a mounting frame 5.9 is arranged on a top plate of the door-shaped frame 5.1, a recycling box 5.2 extending upwards is fixedly connected in the mounting frame 5.9, an opening at the bottom of the recycling box 5.2 is arranged, and a notch matched with the recycling box 5.2 is formed in the top plate of the door-shaped frame 5.1, so that a slide glass 3 can pass smoothly; a pair of supporting and limiting components for preventing the glass slide 3 from falling are symmetrically arranged on the side wall of the recovery box 5.2, a pushing handle component with translation and jacking functions is arranged below the portal frame 5.1 through a vertical column, a jacking block 5.3 of the pushing handle component vertically reciprocates between the portal frame 5.1 and the recovery box 5.2, the pushing handle component comprises a horizontal plate 5.4 erected below the portal frame 5.1, a pair of horizontally arranged recovery guide rails 5.5 are arranged on the horizontal plate 5.4, a base 5.6 driven by a linear cylinder is slidably arranged on the recovery guide rails 5.5, a lifting cylinder piston rod below the base 5.6 extends upwards out of the base 5.6 and is fixedly connected with a jacking block 5.3, at least two groups of wedge-shaped limiting blocks 5.10 are symmetrically arranged on the left edge and the right edge of the jacking block 5.3, and inclined planes inside the wedge-shaped limiting blocks 5.10 are matched with the glass slide 3; the support limiting component comprises a wedge-shaped block 5.7 hinged to the side wall of the recovery box 5.2, a torsion spring 5.8 is sleeved on a hinge shaft of the wedge-shaped block 5.7, and the wedge-shaped block 5.7 not only can ensure smooth passing of a glass slide, but also has a limiting supporting effect and prevents the glass slide from falling. The slide glass recycling mechanism not only realizes automatic recycling of the slide glass 3, but also can store the slide glass 3 after the slide glass is read according to the slide reading sequence, is convenient for later searching and re-reading, completely avoids manual intervention, improves the detection efficiency, realizes standardization and standardization of the slide glass, and provides convenience for detection, scientific research and teaching.
When the slide glass is read, a mechanical gripper firstly grabs a slide glass 3 to be read and moves to a position aligned with an objective table of the microscope 2 along a transverse guide rail 4.1, a rotary cylinder drives a clamping arm 4.3 to rotate to a position right above the objective table through a rotary support 4.5, a screw rod stepping motor adjusts the height of the clamping arm 4.3 through an L-shaped lifting plate 4.6 to enable the slide glass to be positioned right on the objective table, the slide glass is loosened through the clamping cylinder 4.7, the transfer action of the slide glass 3 is completed, the microscope 2 automatically scans and reads sample information on the slide glass 3, and an upper computer of the microscope 2 automatically stores and analyzes the sample information; while reading the film, the jacking block 5.3 moves leftwards to the maximum stroke of the linear cylinder along the recovery guide rail 5.5 through the base 5.6, and the jacking block 5.3 is positioned between the recovery box 5.2 and the microscope 2; after the reading is completed, the mechanical gripper grabs the slide glass 3 after the reading and moves to the right above the jacking block 5.3 along the transverse guide rail 4.1, and the mechanical gripper places the slide glass 3 on the jacking block 5.3; the jacking block 5.3 is retracted below the recovery box 5.2 under the action of the linear air cylinder, the lifting air cylinder drives the jacking block 5.3 to upwards squeeze the wedge block 5.7, the wedge block 5.7 upwards rotates to enable the glass slide 3 to smoothly enter the recovery box 5.2, the glass slide is restored to an original state under the action of the torsion spring 5.8 through the rear wedge block 5.7, and the glass slide 3 is limited and supported; then the jacking block 5.3 descends under the action of the lifting cylinder and moves leftwards to the right side of the microscope 2 along the recovery guide rail 5.5, so that the next glass slide can be recovered conveniently.
Claims (6)
1. A slide reading system, characterized by: the device comprises a bottom plate (1), wherein a microscope (2) for reading information of a glass slide (3) is arranged on the bottom plate (1), a mechanical gripper for gripping and conveying the glass slide (3) is arranged on the bottom plate (1) positioned at one side of the microscope (2), a glass slide recovery mechanism with translation and jacking functions is arranged on the bottom plate (1) positioned at the other side of the microscope (2), and the mechanical gripper horizontally reciprocates between the microscope (2) and the glass slide recovery mechanism;
The slide glass recycling mechanism comprises a door-shaped frame (5.1) arranged on a bottom plate (1), a recycling box (5.2) with a bottom opening is arranged on a top plate of the door-shaped frame (5.1), a pair of supporting and limiting components for preventing slide glass from falling off are symmetrically arranged on the side wall of the recycling box (5.2), a pushing handle component with translation and jacking functions is arranged below the door-shaped frame (5.1) through a stand column, and a jacking block (5.3) of the pushing handle component vertically reciprocates between the door-shaped frame (5.1) and the recycling box (5.2);
the pushing handle assembly comprises a horizontal plate (5.4) erected below a portal frame (5.1), a pair of transversely extending recovery guide rails (5.5) are arranged on the horizontal plate (5.4), a base (5.6) driven by a linear air cylinder is slidably arranged on the recovery guide rails (5.5), a lifting air cylinder piston rod below the base (5.6) extends upwards out of the base (5.6), and the jacking block (5.3) is fixedly connected to the piston rod;
The supporting and limiting assembly comprises a wedge-shaped block (5.7) hinged to the side wall of the recovery box (5.2), and a torsion spring (5.8) is sleeved on a hinge shaft of the wedge-shaped block (5.7);
the recovery box (5.2) is fixedly connected with the door-shaped frame (5.1) through a mounting frame (5.9) sleeved at the bottom of the recovery box.
2. The slide reading system of claim 1, wherein: the mechanical gripper comprises a transverse guide rail (4.1) arranged on the bottom plate (1), a rotating assembly driven by a power source is arranged on the transverse guide rail (4.1) in a sliding mode, a lifting assembly is arranged on a vertical guide rail (4.2) of the rotating assembly in a sliding mode, and a pair of clamping arms (4.3) used for clamping the glass slide (3) are arranged on the lifting assembly.
3. The slide reading system of claim 2, wherein: the rotary assembly comprises a mounting seat (4.4) arranged on the transverse guide rail (4.1) in a sliding mode, a rotary support (4.5) driven by a rotary air cylinder is arranged on the mounting seat (4.4), and the vertical guide rail (4.2) is arranged on a vertical plate of the rotary support (4.5).
4. The slide reading system of claim 2, wherein: the lifting assembly comprises an L-shaped lifting plate (4.6) which is arranged on a vertical guide rail (4.2) in a sliding manner, a screw rod stepping motor arranged on the rotating assembly drives the L-shaped lifting plate (4.6) to lift, a clamping cylinder (4.7) is arranged on the horizontal part of the L-shaped lifting plate (4.6), two clamping arms (4.3) are respectively and fixedly connected to the clamping heads of the clamping cylinder (4.7), the clamping arms (4.3) are of an L-shaped structure, and limit clamping grooves matched with the glass slide (3) are formed in the horizontal section along the length direction of the clamping arms.
5. The slide reading system of claim 1, wherein: at least two groups of wedge-shaped limiting blocks (5.10) are symmetrically arranged at the left edge and the right edge of the jacking block (5.3), and inclined planes at the inner sides of the wedge-shaped limiting blocks (5.10) are matched with the glass slide (3).
6. The slide reading system of claim 1, wherein: the microscope (2) is a full-automatic microscope.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811614906.7A CN109541792B (en) | 2018-12-27 | 2018-12-27 | Slide reading system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201811614906.7A CN109541792B (en) | 2018-12-27 | 2018-12-27 | Slide reading system |
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CN109541792A CN109541792A (en) | 2019-03-29 |
CN109541792B true CN109541792B (en) | 2024-05-03 |
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CN201811614906.7A Active CN109541792B (en) | 2018-12-27 | 2018-12-27 | Slide reading system |
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CN110208939B (en) * | 2019-05-27 | 2024-05-28 | 平湖莱顿光学仪器制造有限公司 | Slide clamping device and microscope system |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107688232A (en) * | 2017-10-19 | 2018-02-13 | 江苏硕世生物科技股份有限公司 | A kind of microscope carrier, microscope and the method for capturing slide |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107688232A (en) * | 2017-10-19 | 2018-02-13 | 江苏硕世生物科技股份有限公司 | A kind of microscope carrier, microscope and the method for capturing slide |
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