CN109528952A - A kind of compound Chinese medicinal preparation and preparation method thereof with white-skinned face function - Google Patents
A kind of compound Chinese medicinal preparation and preparation method thereof with white-skinned face function Download PDFInfo
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The technical program discloses a kind of compound Chinese medicinal preparation and preparation method thereof with white-skinned face function, and the compound Chinese medicinal preparation includes the following component for having parts by weight meter: including 20~40 parts of pearl powder, 10~30 parts of adlay, 25~60 parts of tremella, 5~20 parts of centella, 10~20 parts of purple perilla, 20~25 parts of Rhizoma Atractylodis Macrocephalae, 20~25 parts of jujube.The compound Chinese medicinal preparation that the technical program provides has inhibits melanin production, desalination pigementation well；And the compound Chinese medicinal preparation in the technical program contains plurality of Chinese active constituent, can be effectively facilitated the metabolism, small to skin irritatin of skin.
Description
Technical field
The technical program belongs to technical field of traditional Chinese medicine preparation, in particular to a kind of compound Chinese medicinal preparation with white-skinned face function
And preparation method thereof.
Background technique
The mechanism that the black pigment of skin is formed is main are as follows: the forming process of melanocyte exists and the tyrosine in melanocyte tissue
It is gradually converted under the action of the enzymes such as tyrosinase through intermediates such as DOPA, DOPA quinone, dopachrome, dihydroxy indoles very black
Element, and then melanocyte is transferred in Epidermal basal layer cells by melanocyte tissue, is brought to angle with the metabolism of cell
In matter layer, finally fall off with keratinocyte.But due to by ultraviolet light, heredity, endocrine, inflammatory mediator, improper diet etc.
The influence of factor, Melanin Metabolism are abnormal, the black pigment of skin excessively rapid growth and are unevenly distributed, and will result in that local skin is excessively black and pigment
Calmness shows as pigmentation etc. after chloasma, freckle and inflammation.
Current existing whitening product is addition mostly using the cutin-softenings such as salicylic acid promotion stratum corneum, then again
The fluorescence skin lightening factor directly brightened is added to be prepared, although these products can make skin whitening occur in a short time
Effect, but it is this be easy by way of accelerating stratum corneum so that keratoderma is thinning, skin sensitivity；And the beauty that hydrogen is female
White effect is fine, but the female side effect of hydrogen is excessive and disabled；Kojic acid and its derivative whitening function are strong, but meet easy point of light, heat
Solution, the whitening preparation containing chemical component or heavy metal are easy to cause Skin pigmentation after, and side effect is larger.
Summary of the invention
The technical program provides a kind of compound Chinese medicinal preparation and preparation method thereof with white-skinned face function, the Chinese medicine compound prescription
Preparation has white-skinned face function, and small to skin irritatin.
To achieve the above object, the technical program uses following technological means.
A kind of compound Chinese medicinal preparation with white-skinned face function, the compound Chinese medicinal preparation include the following group for having parts by weight meter
Part: including 20~40 parts of pearl powder, 10~30 parts of adlay, 25~60 parts of tremella, 5~20 parts of centella, 10~20 parts of purple perilla, white
20~25 parts of art, 20~25 parts of jujube.
Further, the compound Chinese medicinal preparation includes the following component for having parts by weight meter: including 20~30 parts of pearl powder,
20~25 parts of adlay, 30~45 parts of tremella, 10~15 parts of centella, 10~15 parts of purple perilla, 20~25 parts of Rhizoma Atractylodis Macrocephalae, jujube 20~25
Part.
Further, the partial size of the pearl powder is 200~300nm.
Further, the acceptable carriers of the extract of each raw material are prepared into ointment, emulsifiable paste or gel.
A kind of preparation method of the compound Chinese medicinal preparation with white-skinned face function, comprising the following steps:
(1) it is matched according to component described above, tremella, adlay, purple perilla, centella, Rhizoma Atractylodis Macrocephalae, jujube is taken to be ground into carefully
Then plus Extraction solvent refluxing extraction 2 to 4 times powder, spare, reflux 1 to 3 hours every time, combined extract filters, goes filtrate,
Concentrated medicament adds ethanol precipitation, Chinese medical extract A is made；
(2) Chinese medical extract A made from step (1) is mixed with pearl powder to get the compound Chinese medicinal preparation is arrived.
Further, the Extraction solvent is water.
Further, the concentration of alcohol is 85%~90%.
Further, tremella, adlay, purple perilla, centella, Rhizoma Atractylodis Macrocephalae, jujube is taken to be ground into fine powder, wherein the average grain of fine powder
Diameter is 200~300 mesh.
The technical program the utility model has the advantages that the technical program provides a kind of compound Chinese medicinal preparation with white-skinned face function, institute
Stating compound Chinese medicinal preparation includes pearl powder, adlay, tremella, centella, purple perilla, Rhizoma Atractylodis Macrocephalae, jujube；The wherein main component of pearl powder
Mainly there are protein, calcium carbonate, 20 various trace elements and vitamin B；Pearl powder can promote the intracorporal collagenocyte of people raw
It is long, the metabolism of skin cell can be accelerated, accelerate mediating, aging, falling off for pigment；In pearl powder exclusive bioactivity at
Divide the activity that can effectively inhibit tyrosine, reduces melanin production, achieve the effect that desalination and eliminate color spot；Micro member in pearl
Element can promote the quantity of SOD to increase, increased activity, selenium be manufacture glutathione peroxidase main matter, this enzyme with
SOD is the same to be removed free radical, improve the colour of skin；
Adlay is cool in nature, sweet in flavor, light, has effects that invigorating the spleen excreting dampness, remove numbness antidiarrheal, and adlay is rich in vitamin B1, vitamin
B2, niacin, vitamin E, multi mineral prime element；Wherein vitamin B1, vitamin B2, vitamin E can effectively keep human body
Skin gloss is fine and smooth, is eliminating acne, freckle, senile plaque etc.；
In tremella contain a large amount of protein, fat, carbohydrate, vitamin A, B, C, D, E and mineral calcium, magnesium,
Phosphorus, iron etc., tremella are rich in natural plant colloid, and long-term use can be with moisturizing, and has the function for taking out face's chloasma, freckle
Effect, if external application, can also be absorbed by the skin, and generate same effect；
Centella is cold in nature, bitter, pungent, and there is affectionate dampness removing, the efficacy of removing toxicity for detumescence to imitate；Contain Asiaticoside in centella,
This ingredient can not only influence fibroblastic ultra microstructure, and can inhibit the conjunction of fibroblast proliferation and collagen
At；Centella contains asiatic acid and brahmic acid, these ingredients can effectively have Propiobacterium, staphylococcus aureus
Definitely inhibiting effect；
Active constituent rich in purple perilla, has inhibiting effect to multiple-microorganism, the Rosmarinic acid energy in purple perilla
Inhibit hyaluronidase activity, can keep hyaluronic acid epidermal cell for a long time exist, can play it is anti-infective, go color spot,
It is anti-oxidant, increase elasticity the effects of；
It is Rhizoma Atractylodis Macrocephalae bitter, sweet, it is warm-natured；There is the effect of strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect；And Rhizoma Atractylodis Macrocephalae also have it is anti-oxidant, prolong
The effect of slow aging；Rhizoma Atractylodis Macrocephalae can effectively anti-lipid peroxidation act on, and reduce the content of tissue lipid peroxide, avoid nocuousness
Destruction of the substance to tissue cellularity and function；
Jujube is rich in protein, fat, carbohydrate, carrotene, B family vitamin, vitamin C, citrin and phosphorus, calcium, iron
Equal ingredients；Jujube has effects that promote hyperplasia, delaying cell aging；
The compound Chinese medicinal preparation that the technical program provides has inhibits melanin production, desalination pigementation well；And
And the compound Chinese medicinal preparation in the technical program contains plurality of Chinese active constituent, can be effectively facilitated skin metabolism,
It is small to skin irritatin.
Specific embodiment
Below with reference to technical effect of the embodiment to the design of the technical program, specific structure and generation carry out it is clear,
It is fully described by, to be completely understood by the purpose, feature and effect of the technical program.
Embodiment 1
A kind of compound Chinese medicinal preparation with white-skinned face function, the compound Chinese medicinal preparation include the following group for having parts by weight meter
Part: including 20 parts of pearl powder, 10 parts of adlay, 25 parts of tremella, 5 parts of centella, 10~20 parts of purple perilla, 20 parts of Rhizoma Atractylodis Macrocephalae, 20 parts of jujube,
The partial size of the pearl powder is 200~300nm.
A kind of preparation method of the compound Chinese medicinal preparation with white-skinned face function, comprising the following steps:
(1) it is matched according to component described in claim 1 or claim 2, takes tremella, adlay, purple perilla, centella, white
Then plus Extraction solvent refluxing extraction 2 to 4 times art, jujube are ground into fine powder, spare, and, reflux 1 to 3 hours, merge and extract every time
Liquid filters, goes filtrate, and concentrated medicament adds ethanol precipitation, Chinese medical extract A is made；
(2) Chinese medical extract A made from step (1) is mixed with pearl powder to get the compound Chinese medicinal preparation is arrived.
Further, the Extraction solvent is water.
Further, the concentration of alcohol is 85%.
Further, tremella, adlay, purple perilla, centella, Rhizoma Atractylodis Macrocephalae, jujube is taken to be ground into fine powder, wherein the average grain of fine powder
Diameter is 200~300 mesh.
Carbomer will be added in compound Chinese medicinal preparation obtained, the Traditional Chinese medicine gel containing the compound Chinese medicinal preparation is made
Agent.
Embodiment 2
A kind of compound Chinese medicinal preparation with white-skinned face function, the compound Chinese medicinal preparation include the following group for having parts by weight meter
Part: including 30 parts of pearl powder, 25 parts of adlay, 45 parts of tremella, 15 parts of centella, 15 parts of purple perilla, 25 parts of Rhizoma Atractylodis Macrocephalae, 25 parts of jujube, institute
The partial size for stating pearl powder is 200~300nm.
The preparation method of compound Chinese medicinal preparation described in embodiment 2 is identical as preparation method described in embodiment 1.
Select 90 ages at 26~40 years old, women of the average age at 35 years old, patient shows as that face skin is obscure, hair
Huang has color spot；2 groups will be randomly divided into: example 1 group and 2 groups of embodiment, example 1 group, which uses, is made medicament in embodiment 1,
2 groups of embodiment are smeared full face using medicament obtained in embodiment 2, every night, are used continuously 28 days.
Criterion of therapeutical effect: effective: facial color area recession 60%, color spot has desalination；Improve: facial color area subsides
30%~60%, color spot has desalination；It is invalid: color area subside 30% hereinafter, color spot without desalination.
Treatment results are shown in table 1.
1 example 1 group of table and 2 groups of embodiment for the treatment of results
| Group | It is effective | It improves | In vain |
| Embodiment 1 | 30 | 11 | 4 |
| Embodiment 2 | 32 | 10 | 3 |
The whitening spot-removing of compound Chinese medicinal preparation described in the technical program works well as can be seen from Table 1.
Allergic conditions are used in 2 example 1 group of table and 2 groups of embodiment
| Group | Allergy | Without allergy |
| Embodiment 1 | 3 | 42 |
| Embodiment 2 | 4 | 41 |
As can be seen from Table 2 example 1 group with 2 groups of embodiment in only only a few using in described in the technical program
Medicine compound preparation allergy, it can be said that the compound Chinese medicinal preparation in bright the technical program is small to skin irritatin.
The better embodiment of the technical program is illustrated above, but the technical program be not limited to it is described
Embodiment, those skilled in the art can also make various equivalent changes under the premise of without prejudice to the technical program spirit
Type or replacement, these equivalent variation or replacement are all included in the scope defined by the claims of the present application.
Claims (8)
1. a kind of compound Chinese medicinal preparation with white-skinned face function, which is characterized in that the compound Chinese medicinal preparation include it is following have weight
Measure the component of part meter: including 20~40 parts of pearl powder, 10~30 parts of adlay, 25~60 parts of tremella, 5~20 parts of centella, purple perilla
10~20 parts, 20~25 parts of Rhizoma Atractylodis Macrocephalae, 20~25 parts of jujube.
2. a kind of compound Chinese medicinal preparation with white-skinned face function according to claim 1, which is characterized in that the Chinese medicine is multiple
Square preparation includes the following component for having parts by weight meter: including 20~30 parts of pearl powder, 20~25 parts of adlay, 30~45 parts of tremella,
10~15 parts of centella, 10~15 parts of purple perilla, 20~25 parts of Rhizoma Atractylodis Macrocephalae, 20~25 parts of jujube.
3. according to claim 1 or a kind of compound Chinese medicinal preparation with white-skinned face function as claimed in claim 2, feature exist
In the partial size of the pearl powder is 200~300nm.
4. according to claim 1 or a kind of compound Chinese medicinal preparation with white-skinned face function as claimed in claim 2, feature exist
In the acceptable carriers of the extract of each raw material are prepared into ointment, emulsifiable paste or gel.
5. a kind of preparation method of the compound Chinese medicinal preparation with white-skinned face function, which comprises the following steps:
(1) according to compound Chinese medicinal preparation described in claim 1 or claim 2 component match, take tremella, adlay, purple perilla,
Then plus Extraction solvent refluxing extraction 2 to 4 times centella, Rhizoma Atractylodis Macrocephalae, jujube are ground into fine powder, spare, and, reflux 1 to 3 is small every time
When, combined extract filters, goes filtrate, and concentrated medicament adds ethanol precipitation, Chinese medical extract A is made；
(2) Chinese medical extract A made from step (1) is mixed with pearl powder to get the compound Chinese medicinal preparation is arrived.
6. a kind of preparation method of compound Chinese medicinal preparation with white-skinned face function according to claim 5, which is characterized in that
The Extraction solvent is water.
7. a kind of preparation method of compound Chinese medicinal preparation with white-skinned face function according to claim 5, which is characterized in that
The concentration of alcohol is 85%~90%.
8. a kind of preparation method of compound Chinese medicinal preparation with white-skinned face function according to claim 5, which is characterized in that
Tremella, adlay, purple perilla, centella, Rhizoma Atractylodis Macrocephalae, jujube is taken to be ground into fine powder, wherein the average grain diameter of fine powder is 200~300 mesh.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811616836.9A CN109528952A (en) | 2018-12-27 | 2018-12-27 | A kind of compound Chinese medicinal preparation and preparation method thereof with white-skinned face function |
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| CN201811616836.9A CN109528952A (en) | 2018-12-27 | 2018-12-27 | A kind of compound Chinese medicinal preparation and preparation method thereof with white-skinned face function |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| CN102836110A (en) * | 2012-08-21 | 2012-12-26 | 青岛文创科技有限公司 | Whitening mask |
| CN103099767A (en) * | 2013-02-26 | 2013-05-15 | 苏州市洋海电子有限公司 | Traditional Chinese medicine whitening mask |
| CN106913483A (en) * | 2017-03-15 | 2017-07-04 | 肖志远 | Face mask of traditional Chinese medicine |
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2018
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|---|---|---|---|---|
| CN102613625A (en) * | 2012-03-20 | 2012-08-01 | 杨军 | Method for preparing coix seed beauty drink |
| CN102836110A (en) * | 2012-08-21 | 2012-12-26 | 青岛文创科技有限公司 | Whitening mask |
| CN103099767A (en) * | 2013-02-26 | 2013-05-15 | 苏州市洋海电子有限公司 | Traditional Chinese medicine whitening mask |
| CN106913483A (en) * | 2017-03-15 | 2017-07-04 | 肖志远 | Face mask of traditional Chinese medicine |
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| 吴河娜: "《种出来的香气》", 30 September 2014, 吉林科学技术出版社 * |
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