CN109528939A - Traditional Chinese medicine compound composition and preparation method thereof for treating chronic kidney disease - Google Patents

Traditional Chinese medicine compound composition and preparation method thereof for treating chronic kidney disease Download PDF

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CN109528939A
CN109528939A CN201811431099.5A CN201811431099A CN109528939A CN 109528939 A CN109528939 A CN 109528939A CN 201811431099 A CN201811431099 A CN 201811431099A CN 109528939 A CN109528939 A CN 109528939A
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chinese medicine
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compound composition
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李松
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Abstract

The invention belongs to Traditional Chinese medicine compound composition technical fields, in particular for treating the Traditional Chinese medicine compound composition and preparation method thereof of chronic kidney disease, including the raw material of following parts by weight: 3-6 parts of rheum officinale, 1-1.5 parts of the dried immature fruit of citron orange, 3-6 parts of radix paeoniae rubra, 3-6 parts of Radix Glycyrrhizae, 5-10 parts of radix ranunculi ternati, 3-6 parts of Rhizoma Chuanxiong, 5-10 parts of Radix Rehmanniae, 5-10 parts of peach kernel, 1-1.5 parts of Verbena officinalis, 10-15 parts of motherwort, 5-10 parts of rhizoma imperatae, fine powder is worn into peach kernel peeling, by safflower, radix achyranthis bidentatae, rheum officinale, the dried immature fruit of citron orange, radix paeoniae rubra, Radix Glycyrrhizae, radix ranunculi ternati, Rhizoma Chuanxiong etc. is cleaned, it adds water to cook three times, it obtains decocting mixed extract, mixed extract will be decocted and stand 10-12 hours, extracting solution Chinese medicine slag is filtered, obtain concentrate, it is in confection that preparation in concentrate, which is added, in peach kernel powder, Obtain Traditional Chinese medicine compound composition.Clearing heat and cooling blood of the present invention, enriching yin, cooling and activating blood, the effect of activating microcirculation and removing stasis medicinal can be realized.

Description

Traditional Chinese medicine compound composition and preparation method thereof for treating chronic kidney disease
Technical field
The present invention relates to Traditional Chinese medicine compound composition technical fields, more particularly, to treat the Chinese medicine compound prescription of chronic kidney disease Composition and preparation method thereof.
Background technique
Chronic kidney disease (Chronic Kidney Disease, CKD) is clinically comprehensive including chronic glomerulonephritis, nephrosis Simulator sickness, membranous nephropathy, diabetic nephropathy, hypertensive nephropathy and various secondary nephrosis etc. have disease incidence height, suffer from blood of making up one's mind The feature that pipe disease illness rate is high, case fatality rate is high, in addition society is not high to the awareness of chronic kidney disease, and control rate is low, and trouble is made up one's mind The awareness of angiosis is low, has become the open health problem in the whole world at present.Chronic kidney disease illness rate rises year by year, serious shadow National life quality is rung, for chronic kidney disease as do not controlled in time, patient will progress into end-stage renal disease, need throughout one's life Row renal replacement therapies, consume a large amount of medical insurance funds, cause serious commercial to bear to individual, family, society, for chronic kidney Disease, doctor trained in Western medicine is mostly to control primary disease (glomerulonephritis, diabetes, hypertension etc.) at present, anticoagulant, platelet aggregation-against treatment Based on, though can delay the progress of part disease, most of patients curative effect is poor, is unable to control disease complications, while long-term Liver caused by oral western medicine preparation, renal damage and hemorrhage of digestive tract are difficult to avoid that raw Radix Astragali, Chinese medicine thinks that Radix Astragali can be mended The gas of the whole body has rising Yang, strengthening exterior and reducing sweat, apocenosis myogenic, inducing diuresis for removing edema, the effect of miscarriage prevention benefit blood concurrently.For anaemia, edema, body Empty hidrosis, threatened abortion, uterine prolapse, qi-blood deficiency, deficiency of Yin deficiency etc. have distinguished curative effect.Singly take Radix Astragali is soaked to drink, It is sleepy that body can be controlled, powerless, shortness of breath.After Mr.'s Hu Shi middle age, feel dog-tired gradually, it is unable to do what one wishes, it is soaked just to commonly use Radix Astragali It uses on behalf of the tea.Especially before teaching, several mouthfuls of Radix Astragali water are always first sipped, so that energy doubles, say that One's voice is like a great bell for words, flood Flood is without cease.It is above-mentioned to solve to design Traditional Chinese medicine compound composition for treating chronic kidney disease and preparation method thereof for we thus Problem.
Summary of the invention
The purpose of the present invention is to solve disadvantages existing in the prior art, and what is proposed is used to treat chronic kidney disease Traditional Chinese medicine compound composition and preparation method thereof.
To achieve the goals above, present invention employs following technical solutions:
For treating the Traditional Chinese medicine compound composition of chronic kidney disease, the raw material including following parts by weight: Radix Astragali 5-20 parts raw, It is 5-10 parts of caulis sinomenii, 10-15 parts of rhizoma dioscoreae nipponicae, white 10-15 parts of the grass in river, 3-6 parts of rheum officinale, 1-1.5 parts of the dried immature fruit of citron orange, 3-6 parts of radix paeoniae rubra, sweet 3-6 parts careless, 5-10 parts of radix ranunculi ternati, 3-6 parts of Rhizoma Chuanxiong, 5-10 parts of Radix Rehmanniae, 5-10 parts of peach kernel, 20-30 parts of safflower, radix achyranthis bidentatae 10-15 Part, 1-1.5 parts of Verbena officinalis, 10-15 parts of motherwort, 5-10 parts of rhizoma imperatae.
Preferably, the raw material of following parts by weight: raw Radix Astragali 6-19 parts, 6-9 parts of caulis sinomenii, 11-14 parts of rhizoma dioscoreae nipponicae, the white grass in river 11-14 parts, 40 parts of rheum officinale, 1-1.5 parts of the dried immature fruit of citron orange, 3-6 parts of radix paeoniae rubra, 3-6 parts of Radix Glycyrrhizae, 5-10 parts of radix ranunculi ternati, 3-6 parts of Rhizoma Chuanxiong, Radix Rehmanniae 5-10 parts, 5-10 parts of peach kernel, 20-30 parts of safflower, 10-15 parts of radix achyranthis bidentatae, 1-1.5 parts of Verbena officinalis, 10-15 parts of motherwort, rhizoma imperatae 5-10 parts.
Preferably, the raw material of following parts by weight: raw 12 parts of Radix Astragali, 7 parts of caulis sinomenii, 12 parts of rhizoma dioscoreae nipponicae, river are careless 12 parts white, big Yellow 4.5 parts, 1.25 parts of the dried immature fruit of citron orange, 4.5 parts of radix paeoniae rubra, 4.5 parts of Radix Glycyrrhizae, 7.5 parts of radix ranunculi ternati, 4.5 parts of Rhizoma Chuanxiong, 7.5 parts of Radix Rehmanniae, peach kernel 7.5 parts, 25 parts of safflower, 12.5 parts of radix achyranthis bidentatae, 1.25 parts of Verbena officinalis, 12.5 parts of motherwort, 7.5 parts of Radix Rehmanniae.
Preferably, the peach kernel is powdery.
Preferably, the weight ratio of the safflower, motherwort, rhizoma imperatae, radix achyranthis bidentatae and peach kernel is 6-10:5:3:5:3.
For treating the preparation method of the Traditional Chinese medicine compound composition of chronic kidney disease, comprising the following steps:
S1 after removing the peel peach kernel, is put into grinding device, is fully ground into fine powder, spare；
S2, by raw Radix Astragali, caulis sinomenii, rhizoma dioscoreae nipponicae, the white grass in river, safflower, radix achyranthis bidentatae, rheum officinale, the dried immature fruit of citron orange, radix paeoniae rubra, Radix Glycyrrhizae, ram's horn It after grass, Rhizoma Chuanxiong, Radix Rehmanniae, Verbena officinalis, motherwort, rhizoma imperatae clean up, adds water to cook three times, first time 3-5 hour, second It 2-4 hours, third time 1-3 hours, obtains decocting mixed extract；
Extracting solution Chinese medicine slag is filtered, is obtained behind decoction mixed extract cooling and standings 10-12 hours in S2 by S3 Concentrate；
S4, it is in confection that preparation in the concentrate in S3, which is added, in the peach kernel powder in S1, obtains Traditional Chinese medicine compound composition.
Preferably, it in the S2, adds water to cook three times, 4 hours for the first time, second 3 hours, third time 2 hours obtains To decoction mixed extract.
Preferably, in the S3, behind the cooling and standings of decoction mixed extract 11 hours in S2, by extracting solution Chinese medicine slag Filtering, obtains concentrate.
Compared with prior art, the beneficial effects of the present invention are: in the present invention, by raw Radix Astragali, caulis sinomenii, rhizoma dioscoreae nipponicae, The white grass in river, rheum officinale, the dried immature fruit of citron orange, radix paeoniae rubra, Radix Glycyrrhizae, radix ranunculi ternati, Rhizoma Chuanxiong, Radix Rehmanniae, peach kernel, safflower, radix achyranthis bidentatae, Verbena officinalis, motherwort, cogongrass Root is to blood urine patient clearing heat and cooling blood, enriching yin, cooling and activating blood, the effect of activating microcirculation and removing stasis medicinal can be realized.
Specific embodiment
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described embodiment Only a part of the embodiment of the present invention, instead of all the embodiments.
Embodiment one
For treating the Traditional Chinese medicine compound composition of chronic kidney disease, the raw material including following parts by weight: raw 5 parts of Radix Astragali, blueness 5 parts of wind rattan, 10 parts of rhizoma dioscoreae nipponicae, river be careless 10 parts white, 3 parts of rheum officinale, 1 part of the dried immature fruit of citron orange, 3 parts of radix paeoniae rubra, 3 parts of Radix Glycyrrhizae, 5 parts of radix ranunculi ternati, Rhizoma Chuanxiong 3 parts, 5 parts of Radix Rehmanniae, 5 parts of peach kernel, 20 parts of safflower, 10 parts of radix achyranthis bidentatae, 1 part of Verbena officinalis, 10 parts of motherwort, 5 parts of rhizoma imperatae.
For treating the preparation method of the Traditional Chinese medicine compound composition of chronic kidney disease, comprising the following steps:
S1 after removing the peel peach kernel, is put into grinding device, is fully ground into fine powder, spare；
S2, by raw Radix Astragali, caulis sinomenii, rhizoma dioscoreae nipponicae, the white grass in river, safflower, radix achyranthis bidentatae, rheum officinale, the dried immature fruit of citron orange, radix paeoniae rubra, Radix Glycyrrhizae, ram's horn It after grass, Rhizoma Chuanxiong, Radix Rehmanniae, Verbena officinalis, motherwort, rhizoma imperatae clean up, adds water to cook three times, 3 hours for the first time, second 2 Hour, third time 1 hour obtains decocting mixed extract；
Extracting solution Chinese medicine slag is filtered, is concentrated behind the cooling and standings of decoction mixed extract 10 hours in S2 by S3 Liquid；
S4, it is in confection that preparation in the concentrate in S3, which is added, in the peach kernel powder in S1, obtains Traditional Chinese medicine compound composition.
Embodiment two
For treating the Traditional Chinese medicine compound composition of chronic kidney disease, the raw material including following parts by weight: raw 12 parts of Radix Astragali, blueness 7 parts of wind rattan, 12 parts of rhizoma dioscoreae nipponicae, river be careless 12 parts white, 4.5 parts of rheum officinale, 1.25 parts of the dried immature fruit of citron orange, 4.5 parts of radix paeoniae rubra, 4.5 parts of Radix Glycyrrhizae, ram's horn Careless 7.5 parts, 4.5 parts of Rhizoma Chuanxiong, 7.5 parts of Radix Rehmanniae, 7.5 parts of peach kernel, 25 parts of safflower, 12.5 parts of radix achyranthis bidentatae, 1.25 parts of Verbena officinalis, motherwort 12.5 parts, 7.5 parts of rhizoma imperatae.
For treating the preparation method of the Traditional Chinese medicine compound composition of chronic kidney disease, comprising the following steps:
S1 after removing the peel peach kernel, is put into grinding device, is fully ground into fine powder, spare；
S2, by raw Radix Astragali, caulis sinomenii, rhizoma dioscoreae nipponicae, the white grass in river, safflower, radix achyranthis bidentatae, rheum officinale, the dried immature fruit of citron orange, radix paeoniae rubra, Radix Glycyrrhizae, ram's horn It after grass, Rhizoma Chuanxiong, Radix Rehmanniae, Verbena officinalis, motherwort, rhizoma imperatae clean up, adds water to cook three times, 4 hours for the first time, second 3 Hour, third time 2 hours obtains decocting mixed extract；
Extracting solution Chinese medicine slag is filtered, is concentrated behind the cooling and standings of decoction mixed extract 11 hours in S2 by S3 Liquid；
S4, it is in confection that preparation in the concentrate in S3, which is added, in the peach kernel powder in S1, obtains Traditional Chinese medicine compound composition.
Embodiment three
For treating the Traditional Chinese medicine compound composition of chronic kidney disease, the raw material including following parts by weight: raw 20 parts of Radix Astragali, blueness 10 parts of wind rattan, 15 parts of rhizoma dioscoreae nipponicae, river be careless 15 parts white, 6 parts of rheum officinale, 1.5 parts of the dried immature fruit of citron orange, 6 parts of radix paeoniae rubra, 6 parts of Radix Glycyrrhizae, 10 parts of radix ranunculi ternati, 6 parts of Rhizoma Chuanxiong, 10 parts of Radix Rehmanniae, 10 parts of peach kernel, 30 parts of safflower, 15 parts of radix achyranthis bidentatae, 1.5 parts of Verbena officinalis, 15 parts of motherwort, rhizoma imperatae 10 Part.
For treating the preparation method of the Traditional Chinese medicine compound composition of chronic kidney disease, comprising the following steps:
S1 after removing the peel peach kernel, is put into grinding device, is fully ground into fine powder, spare；
S2, by raw Radix Astragali, caulis sinomenii, rhizoma dioscoreae nipponicae, the white grass in river, safflower, radix achyranthis bidentatae, rheum officinale, the dried immature fruit of citron orange, radix paeoniae rubra, Radix Glycyrrhizae, ram's horn It after grass, Rhizoma Chuanxiong, Radix Rehmanniae, Verbena officinalis, motherwort, rhizoma imperatae clean up, adds water to cook three times, 5 hours for the first time, second 4 Hour, third time 3 hours obtains decocting mixed extract；
Extracting solution Chinese medicine slag is filtered, is concentrated behind the cooling and standings of decoction mixed extract 12 hours in S2 by S3 Liquid；
S4, it is in confection that preparation in the concentrate in S3, which is added, in the peach kernel powder in S1, obtains Traditional Chinese medicine compound composition.
Blood content in urines is carried out to three groups of embodiment time segments respectively to detect, and compare sell on the market it is of the same race Function medicament, for patient using blood content detection case in five weeks urines of oral agents, experimental result is as in the table below:
Embodiment one
Embodiment two
Embodiment three
Comparative example
By upper table it is found that the oral agents that the present invention makes have preferable matter to Patients with Chronic Renal Disease (blood urine patient) Dose-effect fruit can effectively reduce the blood content of Urine in Patients.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto, Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (8)

1. the Traditional Chinese medicine compound composition for treating chronic kidney disease, which is characterized in that the raw material including following parts by weight: raw yellow 5-20 parts of stilbene, 5-10 parts of caulis sinomenii, 10-15 parts of rhizoma dioscoreae nipponicae, white 10-15 parts of the grass in river, 3-6 parts of rheum officinale, 1-1.5 parts of the dried immature fruit of citron orange, radix paeoniae rubra 3-6 parts, 3-6 parts of Radix Glycyrrhizae, 5-10 parts of radix ranunculi ternati, 3-6 parts of Rhizoma Chuanxiong, 5-10 parts of Radix Rehmanniae, 5-10 parts of peach kernel, 20-30 parts of safflower, radix achyranthis bidentatae 10-15 parts, 1-1.5 parts of Verbena officinalis, 10-15 parts of motherwort, 5-10 parts of rhizoma imperatae.
2. according to claim 1 for treating the Traditional Chinese medicine compound composition of chronic kidney disease, which is characterized in that including with The raw material of lower parts by weight: raw Radix Astragali 6-19 parts, 6-9 parts of caulis sinomenii, 11-14 parts of rhizoma dioscoreae nipponicae, white 11-14 parts of the grass in river, 40 parts of rheum officinale, 1-1.5 parts of the dried immature fruit of citron orange, 3-6 parts of radix paeoniae rubra, 3-6 parts of Radix Glycyrrhizae, 5-10 parts of radix ranunculi ternati, 3-6 parts of Rhizoma Chuanxiong, 5-10 parts of Radix Rehmanniae, 5-10 parts of peach kernel, 20-30 parts of safflower, 10-15 parts of radix achyranthis bidentatae, 1-1.5 parts of Verbena officinalis, 10-15 parts of motherwort, 5-10 parts of rhizoma imperatae.
3. according to claim 1 for treating the Traditional Chinese medicine compound composition of chronic kidney disease, which is characterized in that including with The raw material of lower parts by weight: raw 12 parts of Radix Astragali, 7 parts of caulis sinomenii, 12 parts of rhizoma dioscoreae nipponicae, river be careless 12 parts white, 4.5 parts of rheum officinale, the dried immature fruit of citron orange 1.25 Part, 4.5 parts of radix paeoniae rubra, 4.5 parts of Radix Glycyrrhizae, 7.5 parts of radix ranunculi ternati, 4.5 parts of Rhizoma Chuanxiong, 7.5 parts of Radix Rehmanniae, 7.5 parts of peach kernel, 25 parts of safflower, ox 12.5 parts of knee, 1.25 parts of Verbena officinalis, 12.5 parts of motherwort, 7.5 parts of rhizoma imperatae.
4. according to claim 1 for treating the Traditional Chinese medicine compound composition of chronic kidney disease, which is characterized in that the peach Benevolence is powdery.
5. according to claim 1 for treating the Traditional Chinese medicine compound composition of chronic kidney disease, which is characterized in that described red Flower, motherwort, rhizoma imperatae, radix achyranthis bidentatae and peach kernel weight ratio be 6-10:5:3:5:3.
6. the preparation method for the Traditional Chinese medicine compound composition for treating chronic kidney disease, which comprises the following steps:
S1 after removing the peel peach kernel, is put into grinding device, is fully ground into fine powder, spare；
S2, by raw Radix Astragali, caulis sinomenii, rhizoma dioscoreae nipponicae, the white grass in river, safflower, radix achyranthis bidentatae, rheum officinale, the dried immature fruit of citron orange, radix paeoniae rubra, Radix Glycyrrhizae, radix ranunculi ternati, river It after rhizome of chuanxiong, Radix Rehmanniae, Verbena officinalis, motherwort, rhizoma imperatae clean up, adds water to cook three times, first time 3-5 hour, second of 2-4 is small When, it third time 1-3 hours, obtains decocting mixed extract；
Extracting solution Chinese medicine slag is filtered, is concentrated behind decoction mixed extract cooling and standings 10-12 hours in S2 by S3 Liquid；
S4, it is in confection that preparation in the concentrate in S3, which is added, in the peach kernel powder in S1, obtains Traditional Chinese medicine compound composition.
7. according to claim 6 for treating the preparation method of the Traditional Chinese medicine compound composition of chronic kidney disease, feature It is, in the S2, adds water to cook three times, 4 hours for the first time, second 3 hours, third time 2 hours obtained decoction mixing and mentions Take liquid.
8. according to claim 6 for treating the preparation method of the Traditional Chinese medicine compound composition of chronic kidney disease, feature It is, in the S3, behind the cooling and standings of decoction mixed extract 11 hours in S2, extracting solution Chinese medicine slag is filtered, is obtained Concentrate.
CN201811431099.5A 2018-11-28 2018-11-28 Traditional Chinese medicine compound composition and preparation method thereof for treating chronic kidney disease Pending CN109528939A (en)

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