CN109528893A - A kind of drug and preparation method thereof for treating fracture - Google Patents

A kind of drug and preparation method thereof for treating fracture Download PDF

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CN109528893A
CN109528893A CN201710859006.8A CN201710859006A CN109528893A CN 109528893 A CN109528893 A CN 109528893A CN 201710859006 A CN201710859006 A CN 201710859006A CN 109528893 A CN109528893 A CN 109528893A
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parts
fracture
drug
treatment
blood
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李绍华
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Shanghai Suhu Biotechnology Co Ltd
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A61K36/126—Drynaria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/32—Burseraceae (Frankincense family)
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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Abstract

The invention discloses a kind of drugs and preparation method thereof for treating fracture, are grouped as by following group of parts by weight: 6 ~ 35 parts of the rhizome of davallia, 6 ~ 35 parts of teasel root, 1 ~ 18 part of native copper, 1 ~ 18 part of ground bettle, 0.1 ~ 10 part of dragon's blood, 5 ~ 18 parts of bush, 3 ~ 18 parts of olibanum, 3 ~ 18 parts of myrrh, 1 ~ 25 part of catechu, 6 ~ 25 parts of Radix Salviae Miltiorrhizae, 1 ~ 18 part of Radix Notoginseng, 1 ~ 18 part of safflower, 3 ~ 20 parts of leech, 0.1 ~ 9 part of Moschus；The present invention treats the drug of fracture for treating fracture, and planter cast, does not have to steel nail, and fracture site is without reset processing, and external application of medicinal liquor is for oral administration, and 24 hours fracture sites of resting reset naturally, is further continued for treatment 15 days, reaches recovery from illness；The drug therapy period that the present invention treats fracture is short, thorough treatment.

Description

A kind of drug and preparation method thereof for treating fracture
Technical field
The present invention relates to treatment fracture, the field of Chinese medicines of bone split more particularly to a kind of drug for treating fracture and its preparations Method.
Background technique
Human body is led to bone split, fracture or even the comminuted fracture of itself by external force, causes periosteum, sclerotin and marrow etc. Tissue damage or fracture, while the blood vessel of surrounding bone has also been damaged, cause angiorrhoxis bleeding, forms the hemotoncus in traumatic part. Ideal therapeutic scheme: pass through medication, first removing hemostasis；The hyperplasia teasel root for carrying out bone fracture position again, reaches healing；Most Promote the periosteum for repairing of fracture location afterwards.
But the treatment of general hospital, only do the reparation of bone, the reparation of its hetero-organization such as periosteum, blood vessel because wanting dressing, And treatment cycle is long, costly, and time-consuming, does not treat mostly, only by the natural reparation in later period itself, causes treatment not thorough Bottom, or even future trouble is left, some become larger in appearance in fracture hyperplasia, are thicker, in Changes in weather, sour swollen, pain occur Phenomenon；There is secondary fracture in bone fracture position in some older people.
In addition, the period of traditional treatment fracture is long, normal work and life is drastically influenced.
Summary of the invention
In order to solve the problems, such as that fracture site treatment is not thorough in the prior art or treatment cycle is long, the purpose of the present invention is A kind of drug for treating fracture is provided.For this purpose, the present invention also provides the method for preparing the drug.
To achieve the goals above, the present invention adopts the following technical scheme:
The first aspect of the present invention provides a kind of drug for treating fracture, by the rhizome of davallia, teasel root, native copper, ground bettle, dragon's blood, Bush, olibanum, myrrh, catechu, Radix Salviae Miltiorrhizae, Radix Notoginseng, safflower, leech, Moschus composition.
Preferably, it is grouped as by following group of parts by weight: 6 ~ 35 parts of the rhizome of davallia, 6 ~ 35 parts of teasel root, native copper 1 ~ 18 Part, 1 ~ 18 part of ground bettle, 0.1 ~ 10 part of dragon's blood, 5 ~ 18 parts of bush, 3 ~ 18 parts of olibanum, 3 ~ 18 parts of myrrh, 1 ~ 25 part of catechu, Radix Salviae Miltiorrhizae 6 ~ 25 parts, 1 ~ 18 part of Radix Notoginseng, 1 ~ 18 part of safflower, 3 ~ 20 parts of leech, 0.1 ~ 9 part of Moschus.
The second aspect of the present invention provides the preparation method of the drug of above-mentioned treatment fracture, includes the following steps:
S1 weighs the following component of parts by weight: 6 ~ 35 parts of the rhizome of davallia, 6 ~ 35 parts of teasel root, 1 ~ 18 part of native copper, ground bettle 1 ~ 18 Part, 0.1 ~ 10 part of dragon's blood, 5 ~ 18 parts of bush, 3 ~ 18 parts of olibanum, 3 ~ 18 parts of myrrh, 1 ~ 25 part of catechu, 6 ~ 25 parts of Radix Salviae Miltiorrhizae, Radix Notoginseng 1 ~ 18 parts, 1 ~ 18 part of safflower, 3 ~ 20 parts of leech, 0.1 ~ 9 part of Moschus；
Each component in S1 is calcined respectively, is processed, is dried, is crushed by S2, disinfection treatment；
S3, by S2, treated that each component mixes, and water is added in mixed system, is inoculated with probiotics, cultivates 1-28 days；
S4, the system after S3 is cultivated are sent into distiller, are heated to reflux, and the drug for the treatment of fracture is obtained.
Preferably, content of water in system when being inoculated with probiotics in the S3 is 60-80%.
Preferably, the temperature being heated to reflux in the S4 is 85 DEG C -96 DEG C.
To the mixed Inoculation probiotics of each component, be conducive to the drug effect for increasing each component.The present invention treats bone The drug of folding acts on fracture or bone split position using for oral administration, external application double route, by the efficacy of a drug, and traumatic part is removed in short-term and is become silted up Blood, borrow in vivo, around traumatic part the reticular fibre of extravasated blood usually promote the capillary of fracture site, at cellulose cell again It is raw, so that the bone tomography both ends of fracture, while growing in opposite directions, bone fault development poroma, the newborn bone trabecula in poroma is fast Speed increases, so that the bridge poroma of fracture gap is ossify completely, reaches bone healing；During bone growth, newborn hair Blood clot, necrotic tissue caused by thin blood vessel, fibroblast have swallowed because of fracture, and newborn capillary, at fiber Cell carries out self-dsivision breeding with faster speed, achievees the effect that treatment fracture, and promotes healing, rehabilitation comprehensively.
Compared with prior art, the present invention realize the utility model has the advantages that the present invention treat fracture drug for treat fracture, Not planter cast does not have to steel nail, and fracture site is without reset processing, and external application of medicinal liquor is for oral administration, 24 hours fracture site natures of resting It resets, is further continued for treatment 15 days, reaches recovery from illness；The drug therapy period that the present invention treats fracture is short, treats more thorough.
Specific embodiment
Embodiment 1
The preparation method for treating the drug of fracture, includes the following steps:
S1 weighs 60 g of the rhizome of davallia, 60 g of teasel root, 10 g of native copper, 10 g of ground bettle, 1 g of dragon's blood, 50 g of bush, olibanum 30 G, 30 g of myrrh, 10 g of catechu, 60 g of Radix Salviae Miltiorrhizae, 10 g of Radix Notoginseng, 10 g of safflower, 30 g of leech, 1 g of Moschus；
S2, by the rhizome of davallia, teasel root, native copper, ground bettle, dragon's blood, bush, olibanum, myrrh, catechu, Radix Salviae Miltiorrhizae, Radix Notoginseng, safflower, water Leech and Moschus are handled with conventional Chinese medicine calcining, processing, drying, crushing, sterilization process respectively；
S3, by S2, treated that each component is uniformly mixed, and water is added, so that the water content of system is 60%, in aseptic condition Lower inoculation probiotics, sealing fills oxygen culture 25 days, so that bacterium is covered with drug in fact；
The drug for being covered with bacterium reality in S3 is sent into distiller, is heated to 85 DEG C, flows back 24 hours by S4, obtains treatment fracture Drug.
Embodiment 2
The preparation method for treating the drug of fracture, includes the following steps:
S1 weighs 80 g of the rhizome of davallia, 100 g of teasel root, 100 g of native copper, 150 g of ground bettle, 50 g of dragon's blood, 100 g of bush, cream 120 g of perfume, 120 g of myrrh, 100 g of catechu, 100 g of Radix Salviae Miltiorrhizae, 50 g of Radix Notoginseng, 50 g of safflower, 60 g of leech, 20 g of Moschus；
S2, by the rhizome of davallia, teasel root, native copper, ground bettle, dragon's blood, bush, olibanum, myrrh, catechu, Radix Salviae Miltiorrhizae, Radix Notoginseng, safflower, water Leech and Moschus are handled with conventional Chinese medicine calcining, processing, drying, crushing, sterilization process respectively；
S3, by S2, treated that each component is uniformly mixed, and water is added, so that the water content of system is 60%, in aseptic condition Lower inoculation probiotics, sealing fills oxygen culture 25 days, so that bacterium is covered with drug in fact；
The drug for being covered with bacterium reality in S3 is sent into distiller, is heated to 85 DEG C, flows back 24 hours by S4, obtains treatment fracture Drug.
Embodiment 3
The preparation method for treating the drug of fracture, includes the following steps:
S1, weigh 350 g of the rhizome of davallia, 350 g of teasel root, 180 g of native copper, 180 g of ground bettle, 100 g of dragon's blood, 180 g of bush, 180 g of olibanum, 180 g of myrrh, 250 g of catechu, 250 g of Radix Salviae Miltiorrhizae, 180 g of Radix Notoginseng, 180 g of safflower, 200 g of leech, Moschus 90 g；
S2, by the rhizome of davallia, teasel root, native copper, ground bettle, dragon's blood, bush, olibanum, myrrh, catechu, Radix Salviae Miltiorrhizae, Radix Notoginseng, safflower, water Leech and Moschus are handled with conventional Chinese medicine calcining, processing, drying, crushing, sterilization process respectively；
S3, by S2, treated that each component is uniformly mixed, and water is added, so that the water content of system is 60%, in without sterile item Probiotics is inoculated under part, sealing fills oxygen culture 25 days, so that bacterium is covered with drug in fact；
The drug for being covered with bacterium reality in S3 is sent into distiller, is heated to 85 DEG C, flows back 24 hours by S4, obtains treatment fracture Drug.
Treatment method:
For oral administration: three times per day, one after each meal is 30-40 milliliters each.
It is applied with: smearing medical fluid at the vitro skin of fracture site, uniformly smear, be fastened and fractured with absorbent gauze Position is smeared primary for 6 hours.
Through animal experiment, the effect of drug, is as follows:
(1) artificial to cause chicken after comminuted fracture that stand two chicken legs, it can only lie prone motionless, be sprayed at this time with medical fluid Fracture site is simultaneously wrapped up, then feeds 3-4 milliliters of (1/10th of people's taking dose) medical fluids to chicken feed, three times per day, observation.24 is small Shi Hou, chicken leg fracture site nature resetting and setting fracture, while voluntarily normal activity of walking.
(2) identical result is obtained to the experimental result of dog.
The above specific embodiments are only exemplary, is to preferably make skilled artisans appreciate that originally Patent, be not to be construed as include to this patent range limitation；As long as appointing made by the spirit according to disclosed in this patent How with change or modification, the range that this patent includes is each fallen within.

Claims (5)

1. a kind of drug for treating fracture, which is characterized in that by the rhizome of davallia, teasel root, native copper, ground bettle, dragon's blood, bush, cream Perfume, myrrh, catechu, Radix Salviae Miltiorrhizae, Radix Notoginseng, safflower, leech, Moschus composition.
2. the drug for the treatment of fracture as described in claim 1, which is characterized in that be grouped as by following group of parts by weight: bone is broken 6 ~ 35 parts of benefit, 6 ~ 35 parts of teasel root, 1 ~ 18 part of native copper, 1 ~ 18 part of ground bettle, 0.1 ~ 10 part of dragon's blood, 5 ~ 18 parts of bush, olibanum 3 ~ 18 parts, 3 ~ 18 parts of myrrh, 1 ~ 25 part of catechu, 6 ~ 25 parts of Radix Salviae Miltiorrhizae, 1 ~ 18 part of Radix Notoginseng, 1 ~ 18 part of safflower, 3 ~ 20 parts of leech, Moschus 0.1 ~ 9 part.
3. a kind of preparation method of the drug for the treatment of fracture as claimed in claim 1 or 2, which comprises the steps of:
S1 weighs the following component of parts by weight: 6 ~ 35 parts of the rhizome of davallia, 6 ~ 35 parts of teasel root, 1 ~ 18 part of native copper, ground bettle 1 ~ 18 Part, 0.1 ~ 10 part of dragon's blood, 5 ~ 18 parts of bush, 3 ~ 18 parts of olibanum, 3 ~ 18 parts of myrrh, 1 ~ 25 part of catechu, 6 ~ 25 parts of Radix Salviae Miltiorrhizae, Radix Notoginseng 1 ~ 18 parts, 1 ~ 18 part of safflower, 3 ~ 20 parts of leech, 0.1 ~ 9 part of Moschus；
Each component in S1 is calcined respectively, is processed, is dried, is crushed by S2, disinfection treatment；
S3, by S2, treated that each component mixes, and water is added in mixed system, is inoculated with probiotics, cultivates 1-28 days；
S4, the system after S3 is cultivated are sent into distiller, are heated to reflux, and the drug for the treatment of fracture is obtained.
4. the preparation method of the drug for the treatment of fracture as claimed in claim 3, which is characterized in that when being inoculated with probiotics in the S3 Content of water in system be 60-80%.
5. the preparation method of the drug for the treatment of fracture as claimed in claim 3, which is characterized in that the temperature being heated to reflux in the S4 Degree is 85 DEG C -96 DEG C.
CN201710859006.8A 2017-09-21 2017-09-21 A kind of drug and preparation method thereof for treating fracture Pending CN109528893A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111346175A (en) * 2020-04-15 2020-06-30 曾令甲 Oral medicine for treating comminuted fracture
CN113041323A (en) * 2021-03-25 2021-06-29 苏建成 Medicine for treating bone fracture

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Publication number Priority date Publication date Assignee Title
CN1109363A (en) * 1994-12-27 1995-10-04 苑庆祝 Drug for traumatic injury
CN1322565A (en) * 2001-04-18 2001-11-21 魏吉村 Fracture setting pellet
CN1435191A (en) * 2002-01-29 2003-08-13 罗福田 Chinese medicine for bone-knitting and method for preparing same
CN101637549A (en) * 2009-08-13 2010-02-03 王少云 Medicine for treating fracture
CN104524073A (en) * 2014-11-15 2015-04-22 阎贵坤 Coaptation medicine used for treating bone fracture and bone cracking, and preparation method thereof
CN105477237A (en) * 2014-10-08 2016-04-13 刘海燕 Bone reunion pill with improved Bali powder and effects of eliminating stagnant blood and relieving pain for traumatic injury

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1109363A (en) * 1994-12-27 1995-10-04 苑庆祝 Drug for traumatic injury
CN1322565A (en) * 2001-04-18 2001-11-21 魏吉村 Fracture setting pellet
CN1435191A (en) * 2002-01-29 2003-08-13 罗福田 Chinese medicine for bone-knitting and method for preparing same
CN101637549A (en) * 2009-08-13 2010-02-03 王少云 Medicine for treating fracture
CN105477237A (en) * 2014-10-08 2016-04-13 刘海燕 Bone reunion pill with improved Bali powder and effects of eliminating stagnant blood and relieving pain for traumatic injury
CN104524073A (en) * 2014-11-15 2015-04-22 阎贵坤 Coaptation medicine used for treating bone fracture and bone cracking, and preparation method thereof

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Title
刘有亮: "手法治疗四肢闭合性骨折43例", 《中国民间疗法》 *
吴院学等: "接骨Ⅰ号与红药膏治疗骨折168例临床观察 ", 《中医正骨》 *
袁嘉丽: "《微生物学与免疫学》", 31 July 2017 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111346175A (en) * 2020-04-15 2020-06-30 曾令甲 Oral medicine for treating comminuted fracture
CN113041323A (en) * 2021-03-25 2021-06-29 苏建成 Medicine for treating bone fracture

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Application publication date: 20190329