CN102670655B - Externally applied regenerative repair medicinal composition for treating burns and scalds - Google Patents

Externally applied regenerative repair medicinal composition for treating burns and scalds Download PDF

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CN102670655B
CN102670655B CN2012101424327A CN201210142432A CN102670655B CN 102670655 B CN102670655 B CN 102670655B CN 2012101424327 A CN2012101424327 A CN 2012101424327A CN 201210142432 A CN201210142432 A CN 201210142432A CN 102670655 B CN102670655 B CN 102670655B
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externally applied
medicinal composition
pharmaceutical composition
repair
burn
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CN102670655A (en
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卢汉雄
卢雪玲
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何华德
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Abstract

The invention discloses an externally applied medicinal composition for treating burns and scalds, which is characterized by being prepared from the following active ingredients in part by weight: 45 to 95 parts of egg white, 5 to 45 parts of glycerin and 0.5 to 5 parts of bovidae animal horn. The externally applied medicinal composition can fully achieve a compound collaborative treatment effectthrough the synergistic effects of egg white, glycerin and bovidae animal horn; the externally applied medicinal composition has the effects of antibiosis and anti-inflammation; and moreover, the externally applied medicinal composition directly supplies sufficient protein serving as energy required by regenerative repair to deep connective tissue for regenerative repair, so that an ideal therapeutic effect is achieved. The externally applied medicinal composition can rapidly reduce temperature and relieve pain, and does not stimulate wounded parts.

Description

The external Regeneration and Repair pharmaceutical composition for the treatment of burn and scald
Technical field
The present invention relates to a kind of external Regeneration and Repair pharmaceutical composition for the treatment of skin burn.
Background technology
At present, with skin burn with to scald be first degree of signs: the epidermis burn, rodonalgia generally can spontaneous recovery after a few days, preventing from scar.If area is excessive, surpass 20%, can feel sick, symptoms such as vomiting, headache and malaise.Second degree: epidermis holostrome and a corium part are undermined, and blister appears in skin, local edema, and abrasion sometimes, pain is acute.Because corium does not destroy as yet fully, therefore also can there be cicatrix after the healing.The 3rd degree: holostrome skin or subcutaneous tissue, muscle even skeleton are all burnt, and the part is yellow-gray, drying even forms eschar.This type of wound, must treat local necrosis organize come off voluntarily or perform the operation remove after, wound by granulation tissue fill and lead up, edge skin to central authorities' growth, form cicatrix and could heal.Bigger as area, then often need skin-grafting.For above-mentioned skin burn and scald, still there is not comparatively ideal therapeutic scheme at present.
The external used medicine of existing treatment skin burn and scald can not play effects such as antiinflammatory, sterilization and granulation promoting at the main cause that influences damaged cell regeneration and restoration function fully and effectively.
Summary of the invention
Technical problem to be solved by this invention provides a kind of external Regeneration and Repair pharmaceutical composition that can effectively treat skin burn.
The present invention addresses the above problem the technical scheme that adopts to realize: a kind of external Regeneration and Repair pharmaceutical composition for the treatment of burn and scald is characterized in that the effective ingredient proportioning of this pharmaceutical composition is: Ovum Gallus domesticus album 45-95 weight portion, glycerol 5-45 weight portion, angle, hole section beastly angle 0.5-5 weight portion.
Can be preferably, the effective ingredient proportioning of this pharmaceutical composition is: Ovum Gallus domesticus album 79 weight portions, glycerol 20 weight portions, angle, hole section beastly angle 1 weight portion.
Wherein, the beastly angle of described hole angle section is that wherein one or more mixing replaces.Can be preferably, the beastly angle of described hole angle section is Cornu Saigae Tataricae.
Described pharmaceutical composition adds acceptable pharmaceutical necessities according to technology conventional on the pharmaceutics, makes liquid dosage form or semisolid dosage form.
Contain mineral multiple nutritional components such as protein, methionine and silicon, potassium, ferrum, phosphorus, sodium, magnesium, vitamin in the Ovum Gallus domesticus album.Composition and the human body of the gal4 amino acid in the Ovum Gallus domesticus album are the most approaching, are absorbed by skin easily.Ovum Gallus domesticus album also has heat-clearing and toxic substances removing, antiinflammatory, strengthens the effect of skin immune function controlling and protection skin.
Glycerol has another name called glycerol, be a kind of colourless, do not have smell, the thick liquid of sweet in the mouth, can make skin keep moistening softness, high resilience is not subjected to infringements such as dust, weather.
Cornu Saigae Tataricae is the beastly angle of a kind of hole angle section, clinical conventional Chinese medicine, and main effect has blood circulation promoting and blood stasis dispelling, removing toxic substances and promoting subsidence of swelling.
The inventor studied for four more than ten years to the human skin illness, each confluent monolayer cells arrangement form during to skin burn and scald, and the pathological cells metamorphosis in the Regeneration and Repair process of infringement back, reach " fluorescence microscope " combination " H.E " with " light microscopic " and show the basal layer cell arrangement with multiple dyeing such as " antiacid ", connective tissue, blood vessel, nerve and the vasculolymphatic extent of damage etc. are furtherd investigate under the skin corium, thereby determine therapeutic scheme and medicine.When skin burn, when scalding, protein is destroyed under the skin corium, the colloidality osmotic pressure changes, tissue fluid is oozed out and is formed the skin surface blister, this fashion has top layer squamous epithelial cancer parcel, extracts out or pierces through extrusion liquid with syringe, keeps epidermis complete (but bacteriological protection infection) as far as possible, grow new squamous epithelial cancer through the Regeneration and Repair treatment, can reach no scar effect.Analyze its clinical manifestation according to Skin Cell growth and the pathomechanism of top layer squamous cell " bridging ", clinical trial shows, the treatment overall process wants to use in round-the-clock 24 hours the present invention's " burn, scald Regeneration and Repair liquid " to keep the affected part moistening, competent buying not, and this is the basic for the treatment of., come off after the complete bridging of top layer squamous cell through Regeneration and Repair until top layer (the former skin that blister occurs), present the original more glossy ruddy skin of skin and be recovery from illness.This pharmaceutical composition plays the effect of anti-inflammation on the one hand, provides the protein of abundance as the Regeneration and Repair energy needed on the other hand, and the deep layer connective tissue of directly supplying with undermined skin carries out Regeneration and Repair, thereby reaches desirable therapeutic effect.During the treatment, have enough food energies to replenish simultaneously, meat, sugar, the contour energy food of egg can promote the skin regeneration reparation.
The beneficial effect that adopts the present invention to bring: the present invention can give full play to compound recipe Synergistic treatment effect with Ovum Gallus domesticus album, glycerol, the collaborative medication in beastly angle of angle, hole section, plays the effect of anti-inflammation on the one hand; On the other hand the protein of abundance as the Regeneration and Repair energy needed, the deep layer connective tissue that directly offers undermined skin carries out Regeneration and Repair, thereby reaches desirable therapeutic effect.Use the present invention's pain relieving of can lowering the temperature rapidly, do not stimulate the position, affected part.
The specific embodiment
Embodiment 1
A kind of external Regeneration and Repair pharmaceutical composition for the treatment of burn and scald, the effective ingredient proportioning of this pharmaceutical composition is: Ovum Gallus domesticus album 45 weight portions, glycerol 5 weight portions, Cornu Saigae Tataricae 0.5 weight portion.Compositions according to technology conventional on the pharmaceutics, is added acceptable pharmaceutical necessities, make liquid dosage form or semisolid dosage form.
Embodiment 2
A kind of external Regeneration and Repair pharmaceutical composition for the treatment of burn and scald, the effective ingredient proportioning of this pharmaceutical composition is: Ovum Gallus domesticus album 95 weight portions, glycerol 45 weight portions, Cornu Saigae Tataricae 5 weight portions.Compositions according to technology conventional on the pharmaceutics, is added acceptable pharmaceutical necessities, make liquid dosage form or semisolid dosage form.
Embodiment 3
A kind of external Regeneration and Repair pharmaceutical composition for the treatment of burn and scald, the effective ingredient proportioning of this pharmaceutical composition is: Ovum Gallus domesticus album 79 weight portions, glycerol 20 weight portions, Cornu Saigae Tataricae 1 weight portion.Compositions according to technology conventional on the pharmaceutics, is added acceptable pharmaceutical necessities, make liquid dosage form or semisolid dosage form.
Clinical case
One, patient: middle school, Yangshan, Guangdong Province, Lee X qin teacher's son, man, 3 years old.
The main suit: winter in 1979, the whole family ate when sitting around a fire fiery nest, and fiery nest then on the table that strikes lightly, scald by child's both hands and belly.
Diagnosis: be second degree burn.
Analyze: be to be scalded by high hot liquid, blister red and swollen and that differ in size occurs.
Clinical measure: thrust blister with needle tubing every day, takes out most liquid and compress with the sterilization Cotton Gossypii afterwards, makes the top layer be close to the bubble of not leaving a blank, and not infected by alien bacteria as the dark cortex of protection.Spread on the surface, affected part after using cotton cloth to soak into medicine of the present invention in round-the-clock 24 hours during treatment, and constantly keep the affected part moistening, dried buying not, the recovery from illness of two weeks, no cicatrix.
Two, patient: San Shui south, Guangdong Province village, beam X holds, woman, 82 years old.
The main suit: one day in winter in 1976, the household has burnt a basin boiled water, is her foot bath after preparing to add cold water, but she has unexpectedly put both feet in the boiled water basin into the both feet scald.
Diagnosis: be second degree burn.
Analyze: be to be scalded by high hot liquid, blister red and swollen and that differ in size occurs.
Clinical measure: thrust blister with needle tubing every day, takes out most liquid and compress with the sterilization Cotton Gossypii afterwards, makes the top layer be close to the bubble of not leaving a blank, and not infected by alien bacteria as the dark cortex of protection.Spread on the surface, affected part after round-the-clock 24 hours use cotton cloths soak into medicine of the present invention during treatment, and constantly keep the affected part moistening, dried buying fully recovered no cicatrix in 30 days.
Three, patient: this product inventor, Lu Hanxiong, man.
The main suit: nineteen sixty-eight is taken off the end because mentioning a watt nest that fills with rice tamale when holding five joints, and boiling water scalds to both legs and instep portion from hypogastric region, gets blister more than 100.
Diagnosis: be second degree burn.
Analyze: be to be scalded by high hot liquid, blister red and swollen and that differ in size occurs.
Clinical measure: thrust blister with needle tubing every day, takes out most liquid and compress with the sterilization Cotton Gossypii afterwards, makes the top layer be close to the bubble of not leaving a blank, and not infected by alien bacteria as the dark cortex of protection.Spread on the surface, affected part after round-the-clock 24 hours use cotton cloths soak into medicine of the present invention during treatment, and constantly keep the affected part moistening, dried buying fully recovered no cicatrix in 26 days.
Four, patient: old X is gloomy, man, 38 years old; The X of Soviet Union virtue, man, 25 years old.
The main suit: one day in 1958, during whole people's mass movement to make iron and steel, Guangzhou hospital establishes a steel-making pincers pot, and when molten steel was come out of the stove by pincers, spark was shallow at two staff backs, and rubescent and pain is unbearably at once for skin.
Diagnosis: be one to second degree burn.
Analyze: be to be scalded by high hot object, occur red and swollen.
Clinical measure: spread on the surface, affected part after soaking into this medicine with cotton cloth, keep moistening not dried the buying in affected part, pain relieving at once, recovery from illness in three days, no cicatrix.
Five, patient: Liu X, man, 39 years old.
The main suit: in April, 1978 day, when patient (kettleman of Guangzhou hospital) opened fire door and prepares coal, the naked light that is blown out by aerator and hot gas burn hindered hand and face, and part hair ﹑ eyebrow is burnt.
Diagnosis: be one to second degree burn.
Analyze: be to be burnt by the hot naked light of height and gas, occur red and swollen.
Clinical measure: spread on the surface, affected part after soaking into this medicine with cotton cloth, keep moistening not dried the buying in affected part, pain relieving at once, recovery from illness in seven days, no cicatrix.
Liu ﹑ patient: king X group, woman, 31 years old.
The main suit: one day in 1961, both hands were burnt when the cleaning mixture that is made into potassium dichromate and concentrated sulphuric acid in Guangzhou hospital cleaned vessel, and rubescent and pain is unbearably at once for skin.
Diagnosis: be one to second degree burn.
Analyze: be by the chemicals burn, occur red and swollen.
Clinical measure: spread on the surface, affected part after soaking into this medicine with cotton cloth, keep moistening not dried the buying in affected part, pain relieving at once, recovery from illness in three days, no cicatrix.
Seven, patient: what XX, man, 46 years old.
The main suit: because boiled water is poured in the vial, cause explosion one day in November, 2010, in the big foot of a boiling water burn left side then.
Diagnosis: be first degree burn.
Analyze: be to be scalded by high hot liquid, occur red and swollen.
Clinical measure: for testing the effect duration of this medicine, use the medicine of the present invention of preparation before 2 years, spread on the surface, affected part after soaking into this medicine with cotton cloth, again with preservative film parcel (can keep moistening not dried the buying in affected part), pain relieving at once, a drug, recovery from illness in ten hours, no cicatrix.

Claims (3)

1. an external Regeneration and Repair pharmaceutical composition for the treatment of burn and scald is characterized in that the effective ingredient proportioning of this pharmaceutical composition is: Ovum Gallus domesticus album 45-95 weight portion, glycerol 5-45 weight portion, Cornu Saigae Tataricae 0.5-5 weight portion.
2. the external Regeneration and Repair pharmaceutical composition for the treatment of burn and scald according to claim 1 is characterized in that the effective ingredient proportioning of this pharmaceutical composition is: Ovum Gallus domesticus album 79 weight portions, glycerol 20 weight portions, Cornu Saigae Tataricae 1 weight portion.
3. the external Regeneration and Repair pharmaceutical composition for the treatment of burn and scald according to claim 2 is characterized in that: described pharmaceutical composition adds acceptable pharmaceutical necessities according to technology conventional on the pharmaceutics, makes liquid dosage form or semisolid dosage form.
CN2012101424327A 2012-05-09 2012-05-09 Externally applied regenerative repair medicinal composition for treating burns and scalds Expired - Fee Related CN102670655B (en)

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CN2012101424327A CN102670655B (en) 2012-05-09 2012-05-09 Externally applied regenerative repair medicinal composition for treating burns and scalds

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Application Number Priority Date Filing Date Title
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Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1097314A (en) * 1993-07-15 1995-01-18 于艳平 Anti-inflammatory analgetic and detoxicating ointment
CN1053577C (en) * 1994-08-31 2000-06-21 王志友 Medicinal powder for burn and scald
CN1281230C (en) * 2003-04-11 2006-10-25 肖卫 Medicine composition for curing burn, scald and mucocutaneous ulcer

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