CN100998853A - Chinese medicine for treating articular disease and its preparation method - Google Patents

Abstract

A Chinese medicine for treating rheumatic and rheumatoid arthritis, hyperosteogeny, spondylitis, and ischemic femur head necrosis is prepared from 26 Chinese-medicinal materials including Sichuam aconite root, donkey-hide gelatin, phellodendron bark, Chuan-xiong rhizome, etc. Its preparing process is also disclosed.

Description

A kind of Chinese medicine for the treatment of joint disease and preparation method thereof

Technical field

The present invention relates to a kind of Chinese medicine preparation, relate in particular to a kind of Chinese medicine that cures mainly diseases such as rheumatic arthritis, hyperosteogeny, also relate to this preparation method of Chinese medicine.

Background technology

The etiology and pathogenesis of rheumatic and rheumatoid arthritis, hyperosteogeny, neck, breast, spondylitis of lumbar vertebra, this type of disease of ischemic necrosis of femoral head is to belong to the nutrient blood deficiency in origin, cold coagulation expectorant stagnates numbness in muscle, joint, blood vessels, mainly show as limbs joint pain, local swelling, color of the leather is constant, not thirsty in mouthful, pale tongue with white fur, deep-thready pulse; Need treat by warming YANG and invigorating blood, the logical method that stagnates of cold expelling, mostly the medicament of this class disease of existing treatment is can alleviate or disease controlling, and the relapse rate height is difficult to radical cure,

Summary of the invention

Technical problem to be solved by this invention provide a kind of have dispel the wind, invigorate blood circulation, the effect of collateral dredging cures mainly the Chinese medicine of the treatment joint disease of rheumatic and rheumatoid arthritis, hyperosteogeny, neck, breast, spondylitis of lumbar vertebra, ischemic necrosis of femoral head.

Another technical problem to be solved by this invention provides above-mentioned preparation method of Chinese medicine

For achieving the above object, technical scheme of the present invention is: prepare described a kind of raw material for the treatment of the Chinese medicine of joint disease and comprise the refined honey of 1500 grams and 20 Six-element medicines of following weight:

The Radix Aconiti 63 gram Radixs Angelicae Dahuricae 63 gram Colla Corii Asini 63 grams

The Cortex Eucommiae 63 gram Agkistrodons 63 gram Rhizoma Atractylodis 63 grams

Cortex Phellodendri 63 gram Radix Gentianae Macrophyllae 63 gram Fructus Chaenomeliss 63 grams

Semen Plantaginis 63 gram Rhizoma Chuanxiongs 63 gram Radix Aconiti Kusnezoffii 63 grams

The Radix Aucklandiae 63 gram Radix Achyranthis Bidentataes 63 gram Radix Clematidis 63 grams

Radix Rehmanniae Preparata 210 gram Radix Angelicae Sinensis 84 gram Cortex Cinnamomis 21 grams

The Rhizoma Zingiberis Preparatum 10.5 gram Semen Sinapis Albaes 42 gram Radixs Linderae 63 grams

Herba Ephedrae 10.5 gram Scolopendras 5 gram Bombyx Batryticatus 84 grams

Fructus Psoraleae 21 gram Radix Glycyrrhizaes 21 grams

As a kind of improvement: sweet degree formed during described refined honey was refined by Mel.

Preparing above-mentioned Chinese medicine is prepared from according to following step:

Step 1,20 Six-element medicated powder as claimed in claim 1 are broken into fine powder, standby;

Step 2, with fine powder and 70 ℃ of-80 ℃ of refined honey uniform mixing, ball is pricked in rubbing;

Step 3, ethane via epoxyethane sterilization were placed 7-10 days;

Step 4, honeyed pill dress box.

Wherein Radix Aconiti, Radix Aconiti Kusnezoffii, function: have the damp eliminating of dispeling the wind, the effect of dispersing cold for relieving pain; The Radix Angelicae Dahuricae, Rhizoma Atractylodis, Fructus Chaenomelis, Radix Clematidis, function: have wind-damp dispelling, analgesic effect; Herba Ephedrae, function: the effect that having has one's ideas straightened out activates yang; Cortex Cinnamomi, Rhizoma Zingiberis Preparatum function: effect with promoting the flow of QI-blood by warming the meridian, dispersing cold for relieving pain; Agkistrodon, Scolopendra, Bombyx Batryticatus, function: the effect that has wind and removing obstruction in channels; Radix Achyranthis Bidentatae, the Cortex Eucommiae, function: effect with Fructus Psoraleae, liver and kidney tonifying, strong muscles and bones; Cortex Phellodendri, Semen Sinapis Albae, function: have dehumidifying expectorant effect; Radix Angelicae Sinensis, thermally, the Colla Corii Asini function: the effect with tonification energy and blood of human body;

A kind of instructions of taking for the treatment of the Chinese medicine of joint disease provided by the invention is: every day 2 times, and each 1-2 ball, 60 days is a course of treatment.

Clinical trial:

1, clinical data:

170 routine rheumatic and patient with rheumatoid arthritis.Treatment group: totally 104 examples, its mild or moderate 24 examples, moderate 62 examples, severe 18 examples; Man's 72 examples, women 32 examples; Minimum 39 years old of age, maximum 79 years old, average 53.3 years old; 2 weeks to 5 of the course of disease year, average 1.17, matched group: totally 66 examples, its mild or moderate 14 examples, moderate 42 examples, severe 10 examples; Man's 32 examples, women 34 examples; Minimum 36 years old of age, maximum 76 years old, average 56.4 years old; 3 weeks to 6 of the course of disease year, average 1.48.Through relative analysis, two groups of ordinary circumstances do not have significant difference, have comparability (P＞0.05).

All cases meet new Chinese medicine treatment of arthritis clinical research guideline standard.

2, Therapeutic Method:

The treatment group adds the Chinese medicine for the treatment of joint disease with a kind of on the basis of conventional Western medicine, each 1-2 ball, and every day 2 times, 60 days is a course of treatment.Matched group is only used conventional western medicine.

Observation item and detection method:

Observe once weekly, observed content comprises clinical symptoms, sign, pulse condition etc., does blood, urine, stool routine examination inspection after taking medicine.

3, result

Curative effect determinate standard is:

Carry out efficacy evaluation according to " new Chinese medicine clinical research guideline " that Ministry of Public Health is formulated.

Produce effects: arthritis, the complete obiteration of neuralgia sings and symptoms.

Effectively: the sings and symptoms major part disappears or alleviates.

Invalid: treat one the course of treatment effect do not have improvement.

Treatment group: produce effects 42 examples, effective 56 examples, invalid 6 examples, total effective rate 94.23%;

Matched group: produce effects 12 examples, effective 40 examples, invalid 14 examples, total effective rate 78.79%;

Two groups of total effective rates relatively have significant difference (P＜0.05), and excellent sub-matched group is organized in treatment.

A kind of treatment by Chinese herbs rheumatic, rheumatoid arthritis for the treatment of joint disease of this clinical trial proof has obvious curative effects.

The specific embodiment

Prepare described a kind of raw material for the treatment of the Chinese medicine of joint disease and comprise the refined honey of 1500 grams and 20 Six-element medicines of following weight:

The Radix Aconiti 63 gram Radixs Angelicae Dahuricae 63 gram Colla Corii Asini 63 grams

The Cortex Eucommiae 63 gram Agkistrodons 63 gram Rhizoma Atractylodis 63 grams

Cortex Phellodendri 63 gram Radix Gentianae Macrophyllae 63 gram Fructus Chaenomeliss 63 grams

Semen Plantaginis 63 gram Rhizoma Chuanxiongs 63 gram Radix Aconiti Kusnezoffii 63 grams

The Radix Aucklandiae 63 gram Radix Achyranthis Bidentataes 63 gram Radix Clematidis 63 grams

Radix Rehmanniae Preparata 210 gram Radix Angelicae Sinensis 84 gram Cortex Cinnamomis 21 grams

The Rhizoma Zingiberis Preparatum 10.5 gram Semen Sinapis Albaes 42 gram Radixs Linderae 63 grams

Herba Ephedrae 10.5 gram Scolopendras 5 gram Bombyx Batryticatus 84 grams

Fructus Psoraleae 21 gram Radix Glycyrrhizaes 21 grams

The raw material of above-mentioned weight can be made 1000 Chinese medicines; Sweet degree formed during described refined honey was refined by Mel.

A kind of Chinese medicine for the treatment of joint disease is prepared from according to following step:

Step 1,20 Six-element medicated powder as claimed in claim 1 are broken into fine powder, standby;

Step 2, with fine powder and 70 ℃ of-80 ℃ of refined honey uniform mixing, ball is pricked in rubbing;

Step 3, ethane via epoxyethane sterilization were placed 7-10 days;

Step 4, honeyed pill dress box.

Claims (3)

1. Chinese medicine for the treatment of joint disease is characterized in that: the raw material for preparing described Chinese medicine comprises the refined honeys of 1500 grams and 20 Six-element medicines of following weight:

The Radix Aconiti 63 gram Radixs Angelicae Dahuricae 63 gram Colla Corii Asini 63 grams

The Cortex Eucommiae 63 gram Agkistrodons 63 gram Rhizoma Atractylodis 63 grams

Cortex Phellodendri 63 gram Radix Gentianae Macrophyllae 63 gram Fructus Chaenomeliss 63 grams

Semen Plantaginis 63 gram Rhizoma Chuanxiongs 63 gram Radix Aconiti Kusnezoffii 63 grams

The Radix Aucklandiae 63 gram Radix Achyranthis Bidentataes 63 gram Radix Clematidis 63 grams

Radix Rehmanniae Preparata 210 gram Radix Angelicae Sinensis 84 gram Cortex Cinnamomis 21 grams

The Rhizoma Zingiberis Preparatum 10.5 gram Semen Sinapis Albaes 42 gram Radixs Linderae 63 grams

Herba Ephedrae 10.5 gram Scolopendras 5 gram Bombyx Batryticatus 84 grams

Fructus Psoraleae 21 gram Radix Glycyrrhizaes 21 grams

2. a kind of Chinese medicine for the treatment of joint disease as claimed in claim 1 is characterized in that: sweet degree formed during described refined honey was refined by Mel.

3. prepare a kind of method for the treatment of the Chinese medicine of joint disease as claimed in claim 1, it is characterized in that: be prepared from according to following step:

Step 1,20 Six-element medicated powder as claimed in claim 1 are broken into fine powder, standby;

Step 2, with fine powder and 70 ℃ of-80 ℃ of refined honey uniform mixing, ball is pricked in rubbing;

Step 3, ethane via epoxyethane sterilization were placed 7-10 days;

Step 4, honeyed pill dress box.