CN109498780A - 一种具有抗肿瘤作用的中药组合物及其制备方法 - Google Patents

一种具有抗肿瘤作用的中药组合物及其制备方法 Download PDF

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CN109498780A
CN109498780A CN201910090868.8A CN201910090868A CN109498780A CN 109498780 A CN109498780 A CN 109498780A CN 201910090868 A CN201910090868 A CN 201910090868A CN 109498780 A CN109498780 A CN 109498780A
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钱兴媄
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Abstract

本发明公开了一种具有抗肿瘤作用的中药组合物及其制备方法,所述中药组合物由以下重量份的药物组成:莪术3‑12份,甘草2‑12份,益母草5‑12份,茯苓5‑15份,垂盆草3‑10份,黄芪5‑10份,半枝莲8‑15份,蛇莓6‑12份,冬凌草5‑10份,蛇床子2‑6份,土大黄4‑10份。有益效果在于:采用纯中药制成,具有益气化瘀、清热解毒、滋阴润肺、止咳化痰的功效,可抑制肿瘤细胞生长的同时提高机体免疫抵抗力,对肿瘤有良好的治愈作用。

Description

一种具有抗肿瘤作用的中药组合物及其制备方法
技术领域
本发明涉及药物制备技术领域,特别是涉及一种具有抗肿瘤作用的中药组合物及其制备方法。
背景技术
随着对肿瘤生物学及肿瘤免疫学研究的不断深入,人类认识到恶性肿瘤的发生发展不仅仅取决于肿瘤细胞本身,还与肿瘤细胞所在的微环境密切相关。肿瘤细胞发生相互作用的基质细胞(包括成纤维细胞、免疫和炎性细胞、血管内皮细胞、脂肪细胞、胶质细胞以及平滑肌细胞等)和细胞外基质形成一个适合肿瘤细胞生长而免疫细胞活性受到抑制的微环境,此微环境在肿瘤发生、浸润、转移过程中扮演着十分重要的角色。传统医学在肿瘤防治中占有重要地位,中药对肿瘤微环境的调节作用相关研究也日益增多,中药对肿瘤微环境各组分的调节可能成为肿瘤防治的新靶点。目前中医治疗癌前病变多以临床辨证为主,很少采取微观辩证,宏观与微观辨证相结合对中医诊断学的发展及指导临床治疗具有重要意义,希望能得到普遍重视。中医药治疗癌症具有方法多样、疗效显著、毒副作用小等特点,在防治癌症 的有效措施方面显示出广阔的前景。
现有技术中,在治疗肿瘤时常采用放疗与化疗等,这些治疗方式会对患者身体造成严重伤害。
发明内容
本发明的目的就在于为了解决上述问题而提供一种具有抗肿瘤作用的中药组合物及其制备方法。
本发明通过以下技术方案来实现上述目的:
一种具有抗肿瘤作用的中药组合物,所述中药组合物由以下重量份的药物组成:莪术3-12份,甘草2-12份,益母草5-12份,茯苓5-15份,垂盆草3-10份,黄芪5-10份,半枝莲8-15份,蛇莓6-12份,冬凌草5-10份,蛇床子2-6份,土大黄4-10份;
进一步的,所述中药组合物由以下重量份的原料制得:莪术8份,甘草10份,益母草6份,茯苓12份,垂盆草7份,黄芪8份,半枝莲12份,蛇莓6份,冬凌草5份,蛇床子2份,土大黄4份。
进一步的,所述药物中土大黄的制作方法为:除去杂质,大小分开,洗净,浸泡4~8小时,取出,闷润12~24小时,至内外湿度一致,切厚片,干燥,筛去碎屑。
本发明还提供所述中药组合物的制备方法,包括如下步骤:取上述重量份的中药,去除杂物,将药物分别放入超微粉碎机中进行粉碎,粉碎成200目的细粉,将药粉混合均匀,包装即成。
本发明的药材功效解析如下:
莪术:味辛、苦,性温;归肝、脾经;行气破血,消积止痛;用于血气心痛,饮食积滞,脘腹胀痛,血滞经闭,痛经,症瘕瘤痞块,跌打损伤;
甘草:味甘,性平;归心、肺、脾、胃经;补脾益气,清热解毒,祛痰止咳,缓急止痛,调和诸药;用于脾胃虚弱,倦怠乏力,心悸气短,咳嗽痰多,脘腹、四肢挛急疼痛,痈肿疮毒,缓解药物毒性、烈性;
益母草:味苦、辛,微寒;归肝、心包、膀胱经;活血调经,利尿消肿,清热解毒;用于月经不调,痛经经闭,恶露不尽,水肿尿少,疮疡肿毒;
茯苓:味甘、淡,性平,归心、肺、脾、肾经,利水渗湿,健脾,宁心,用于水肿尿少,痰饮眩悸,脾虚食少,便溏泄泻,心神不安,惊悸失眠;
垂盆草:味甘、淡,性凉;归肝、胆、小肠经;利湿退黄,清热解毒;用于湿热黄疸,小便不利,痈肿疮疡;
黄芪:性温,味甘;归肺、脾、肝、肾经;补气固表,托毒排脓,利尿,生肌。用于气虚乏力、久泻脱肛、自汗、水肿、子官脱垂、慢性肾炎蛋白尿、糖尿病、疮口久不愈合;
半枝莲:味辛、苦,性寒;归肺、肝、肾经;清热解毒,化瘀利尿;用于疔疮肿毒,咽喉肿痛,跌扑伤痛,水肿,黄疸,蛇虫咬伤;
蛇莓:味甘、苦,性寒;入肺、肝、大肠经;清热解毒,散瘀消肿,凉血止血;热病,惊痫,感冒,痢疾,黄疸,目赤,口疮,咽痛,痄腮,疖肿,毒蛇咬伤,吐血,崩漏,月经不调,烫火伤,跌打肿痛;
冬凌草:味苦、甘,性微寒;归肺、胃、肝经;清热解毒,活血止痛;用于咽喉肿痛,瘕瘕痞块,蛇虫咬伤;
蛇床子:味辛、苦,性温;归肾经;燥湿祛风,杀虫止痒,温肾壮阳;用于阴痒带下,湿疹瘙痒,湿痹腰痛,肾虚阳痿,宫冷不孕;
土大黄;味苦、辛,性凉;入肺、大肠经;清热解毒,凉血止血,祛瘀消肿,通便,杀虫之功效;肺痨咳血,肺痈,吐血,瘀滞腹痛,跌打损伤,大便秘结,痄腮,痈疮肿毒,烫伤,疥癣,湿疹。
本发明的有益效果在于:采用纯中药制成,具有益气化瘀、清热解毒、滋阴润肺、止咳化痰的功效,可抑制肿瘤细胞生长的同时提高机体免疫抵抗力,对肿瘤有良好的治愈作用。
具体实施方式
实施例一:
一种具有抗肿瘤作用的中药组合物,所述中药组合物由以下重量份的原料制得:莪术8份,甘草10份,益母草6份,茯苓6份,垂盆草4份,黄芪8份,半枝莲8份,蛇莓6份,冬凌草8份,蛇床子6份,土大黄10份。
实施例二:
一种具有抗肿瘤作用的中药组合物,所述中药组合物由以下重量份的原料制得:莪术12份,甘草6份,益母草10份,茯苓6份,垂盆草10份,黄芪5份,半枝莲14份,蛇莓6份,冬凌草5份,蛇床子2份,土大黄4份。
典型病例举例:
案例一
王某,男,患淋巴瘤化疗治疗,第一次化疗后恶心呕吐、食欲低下、嗜睡、精神不振,使用本发明实施例1所制中药组合物,将中药组合直接用水冲服,饭后服用,一日三次,15天为一疗程,12个疗程后恶心症状减轻,呕吐、嗜睡状况消失,精神状态好转,无其他不适症状。
案例二
李某,男,30岁,经常感到胸部不适,后逐渐加重并伴有咳嗽,咯血,胸背痛,喘鸣和原因不明的发热等,入院检查确诊为中心型肺癌,且形成大量胸水导致左肩臂疼痛不可忍,医院建议手术及化疗治疗,由于该患者经济条件不好,难以承受,使用本发明实施例1所制中药组合物,将中药组合直接用水冲服,饭后服用,一日三次,15天为一疗程,8个疗程后,疼痛减轻,呼吸顺畅,而且右肺疼痛,呼吸困难的症状已好转。
案例三
秦某,女,58岁,患直肠癌2年,精神身体受到巨大的摧残,长期服用止痛药物,使用本发明实施例1所制中药组合物,将中药组合直接用水冲服,饭后服用,一日三次,15天为一疗程,8个疗程后复查结肠镜,肿块消失。
以上显示和描述了本发明的基本原理、主要特征和优点。本行业的技术人员应该了解,本发明不受上述实施例的限制,上述实施例和说明书中描述的只是说明本发明的原理,在不脱离本发明精神和范围的前提下,本发明还会有各种变化和改进,这些变化和改进都落入要求保护的本发明范围内。

Claims (4)

1.一种具有抗肿瘤作用的中药组合物及其制备方法,其特征在于:所述中药组合物由以下重量份的药物组成:莪术3-12份,甘草2-12份,益母草5-12份,茯苓5-15份,垂盆草3-10份,黄芪5-10份,半枝莲8-15份,蛇莓6-12份,冬凌草5-10份,蛇床子2-6份,土大黄4-10份。
2.根据权利要求1所述的一种具有抗肿瘤作用的中药组合物,其特征在于:所述中药组合物由以下重量份的原料制得:莪术8份,甘草10份,益母草6份,茯苓12份,垂盆草7份,黄芪8份,半枝莲12份,蛇莓6份,冬凌草5份,蛇床子2份,土大黄4份。
3.根据权利要求1所述的一种具有抗肿瘤作用的中药组合物,其特征在于:所述药物中土大黄的制作方法为:除去杂质,大小分开,洗净,浸泡4~8小时,取出,闷润12~24小时,至内外湿度一致,切厚片,干燥,筛去碎屑。
4.一种制备权利要求1所述的一种具有抗肿瘤作用的中药组合物的方法,其特征在于:包括如下步骤:取上述重量份的中药,去除杂物,将药物分别放入超微粉碎机中进行粉碎,粉碎成200目的细粉,将药粉混合均匀,包装即成。
CN201910090868.8A 2019-01-30 2019-01-30 一种具有抗肿瘤作用的中药组合物及其制备方法 Pending CN109498780A (zh)

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CN101590209A (zh) * 2009-06-08 2009-12-02 郭凯 一种治疗肿瘤的药物及其制备方法
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CN103041312A (zh) * 2013-01-10 2013-04-17 南京海昌中药集团有限公司 具有抗肿瘤作用的中药组合物及其制备方法和应用

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CN101590209A (zh) * 2009-06-08 2009-12-02 郭凯 一种治疗肿瘤的药物及其制备方法
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