CN109464294A - A kind of hydrolysis of keratin hair conditioner and preparation method thereof - Google Patents
A kind of hydrolysis of keratin hair conditioner and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/002—Preparations for repairing the hair, e.g. hair cure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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Abstract
The present invention relates to a kind of hydrolysis of keratin hair conditioner, it is made of the raw material of following percentage: hydrolysis of keratin 2-5%, hydrolyzed vegetable protein PG- propyl silane triol 1-3%, hydrolytic collagen 1-3%, collagenous amino acids 0.5-2%, glycerol 5-10%, western song ammonium methyl sulphate 1-3%, cetostearyl alcohol 1-3%, panthenol 1-3%, behenyl base trimethylammoniumethyl sulfate 1-2%, quaternary ammonium salt -330.1-0.3%, guar hydroxypropyltrimonium chloride 0.1-0.3%, allantoin 0.1-0.3%, DMDM hydantoin 0.2-0.4%, EDETATE SODIUM 0.1-0.3%, essence 0.05-0.2%, surplus is deionized water.Hydrolysis of keratin hair conditioner of the invention is suitable for different types of hair quality, from inside to outside fundamentally maintenance damaged hair, and the water of hair is kept to moisten gloss.
Description
Technical field
The invention belongs to daily chemical product technical fields, and in particular to a kind of hydrolysis of keratin hair conditioner and preparation method thereof.
Background technique
Pursuit with people to quality of life and hair aesthetics, hair nursing also receive more attention.Possess one
The healthy hair of submissive health, there is important promotion to the external image of itself.In real daily life, the variation of life style with
And the various extraneous factors such as environmental pollution, hair dyeing, hair-waving, bleaching, ultraviolet light, blowing, temperature will cause the moisture in hair
Be largely lost, hair caused phenomena such as low and deep, withered, bifurcated occur so as to become hair dry and withered and yellow for healthy hair, follow the string and
The hair damage degree of flexibility, people go fromes bad to worse.
Summary of the invention
To overcome the shortcomings of existing technologies, the present invention provides a kind of depth to nourish hair quality, effectively solves hair nutrition and asks
Topic improves the hydrolysis of keratin hair conditioner of hair texture.
A kind of hydrolysis of keratin hair conditioner, is made of the raw material of following percentage: hydrolysis of keratin 2-5%, hydrolyzing plant
Albumen PG- propyl silane triol 1-3%, hydrolytic collagen 1-3%, collagenous amino acids 0.5-2%, glycerol 5-10%, the bent ammonium in west
Methylsulfate 1-3%, cetostearyl alcohol 1-3%, panthenol 1-3%, behenyl base trimethylammoniumethyl sulfate 1-2%, quaternary ammonium
- 33 0.1-0.3% of salt, guar hydroxypropyltrimonium chloride 0.1-0.3%, acyl in allantoin 0.1-0.3%, DMDM second
Urea 0.2-0.4%, EDETATE SODIUM 0.1-0.3%, essence 0.05-0.2%, surplus are deionized water.
Preferably, it is made of the raw material of following percentage: hydrolysis of keratin 4%, hydrolyzed vegetable protein PG- propyl silane three
Alcohol 3%, hydrolytic collagen 2%, collagenous amino acids 1.5%, glycerol 8%, west bent ammonium methyl sulphate 2%, cetostearyl alcohol
2%, panthenol 2%, behenyl base trimethylammoniumethyl sulfate 2%, quaternary ammonium salt -33 0.2%, melon rubber Hydroxyproyl Trimethyl chlorine
Change ammonium 0.1%, allantoin 0.2%, DMDM hydantoin 0.4%, EDETATE SODIUM 0.3%, essence 0.1%, surplus is deionization
Water.
A method of preparing hydrolysis of keratin hair conditioner, it is characterised in that include the following steps:
(1) first deionized water is added in emulsion pot, glycerol, panthenol, EDETATE SODIUM, urine is successively added into emulsion pot
Bursin, guar hydroxypropyltrimonium chloride, quaternary ammonium salt -33 are stirred and heated to 75-80 DEG C, and constant temperature is made to being completely dissolved
Obtain the first mixture;
(2) cetostearyl alcohol, the bent ammonium methyl sulphate in west, behenyl base trimethylammoniumethyl sulfate are added sequentially to again
In oily phase pot, oily phase pot is heated to 75-80 DEG C, the second mixture is made to being completely dissolved in constant temperature;
(3) the second mixture obtained in step (2) is pumped into the emulsion pot of step (1) again, emulsion pot constant temperature 75-
It 80 DEG C, mixes slowly after homogeneous 5min and is cooled to 45 DEG C, third mixture is made;
(4) protein hydrolysate, hydrolyzed vegetable protein PG- propyl silane three are added into third mixture made from step (3)
Alcohol, hydrolytic collagen, collagenous amino acids are stirred to uniformly mixed;DMDM hydantoin, essence are added, is stirred to completely mixed
It closes uniform.
Beneficial effects of the present invention:
(1) a kind of hydrolysis of keratin hair conditioner of the invention is combined using the quaternary ammonium salt and more effect albumen of self-emulsifying,
Wherein: west song ammonium methyl sulphate can improve dry and wet cardability, with excellent moist and film forming characteristics, Conservative restoration hair scale
Piece;Behenyl base trimethylammoniumethyl sulfate is anti-to be wound, is antistatic, and dry and wet cardability, hair scale caused by prevention combing can be improved
Piece damage restores the natural hydrophobicity of hair;Quaternary ammonium salt -33 can make hair healthy be easy to arrange, and repair to chemical damage hair
It is multiple particularly evident;Panthenol can keep the wet of hair, reduce hair bifurcated, be used for a long time and increase hair gloss, prevent from being broken;Melon
Youngster's glue hydroxypropyl-trimethyl ammonium chloride has excellent antistatic property, is suitble to the hair quality of not agnate type, on damaged hair
Performance is especially outstanding, can increase hair plasticity, and prevention fractures and bifurcated, and can be fully dispersed in formula, and increasing is had both after neutralization
Thick effect;Hydrolysis of keratin can enhance hair plasticity, and the anti-anti- bifurcated that breaks, anti-hair aging can form protective keratin membrane
Reduce the injury of environment, chemical action to hair;Hydrolyzed vegetable protein PG- propyl silane triol can infiltrate through hair hair cortex,
Strengthen hair, repairs and protect hair scale piece, enhance hair toughness and Resisting fractre;Hydrolytic collagen has excellent moist and film forming
Characteristic can enhance hair plasticity, and prevention fractures and bifurcated;Collagenous amino acids has natural compatibility to hair, increases hair and grows
Humidity can penetrate into hair core dimension hair and provide moistening effect.
(2) a kind of hydrolysis of keratin hair conditioner use of the present invention is suitble to different types of hair quality, be truly realized take care of hair regardless of
Boundary, regardless of hair quality, fundamentally maintenance damaged hair from inside to outside.Vegetable protein is penetrated into from the interior tough power for establishing hair
It sends out core and repairs damaged hair.A variety of cations are synergistic to form film in hair surface, promotes the deposition of lipophilic active ingredient,
To hair reinforcement protection, the damage that lubricates and prevent hair phase mutual friction from leading to hair scale piece.The present invention complies fully with national promulgation
" cosmetics health specification " (2015 editions) in indices, be free of any potential hazard;And the present invention cannot be only used for head
Returning can be used directly in head scalp.
Specific embodiment
Technical solution of the present invention is illustrated With reference to embodiment.
Embodiment 1
A kind of hydrolysis of keratin hair conditioner of the invention, is made: hydrolysis of keratin 2%, water of the raw material of following percentage
Solve vegetable protein PG- propyl silane triol 1.5%, hydrolytic collagen 1.5%, collagenous amino acids 1%, glycerol 6%, the bent ammonium first in west
Base sulfate 1%, cetostearyl alcohol 1%, panthenol 3%, behenyl base trimethylammoniumethyl sulfate 2%, quaternary ammonium salt -33
0.1%, guar hydroxypropyltrimonium chloride 0.3%, allantoin 0.1%, DMDM hydantoin 0.4%, EDETATE SODIUM
0.1%, essence 0.1%, surplus are deionized water.
A kind of preparation method of hydrolysis of keratin hair conditioner, comprising the following steps:
(1) first deionized water is added in emulsion pot, glycerol, panthenol, EDETATE SODIUM, urine is successively added into emulsion pot
Bursin, guar hydroxypropyltrimonium chloride, quaternary ammonium salt -33 are stirred and heated to 75-80 DEG C, and constant temperature is made to being completely dissolved
Obtain the first mixture.
(2) cetostearyl alcohol, the bent ammonium methyl sulphate in west, behenyl base trimethylammoniumethyl sulfate are added sequentially to again
In oily phase pot, oily phase pot is heated to 75-80 DEG C, the second mixture is made to being completely dissolved in constant temperature.
(3) the second mixture is pumped into the emulsion pot of step (1) again, 75-80 DEG C of emulsion pot constant temperature, after homogeneous 5min
It mixes slowly and is cooled to 45 DEG C, third mixture is made,
(4) protein hydrolysate, hydrolyzed vegetable protein PG- propyl silane three are added into third mixture made from step (3)
Alcohol, hydrolytic collagen, collagenous amino acids are stirred to uniformly mixed;DMDM hydantoin, essence are added, is stirred to completely mixed
It closes uniform.
Embodiment 2
A kind of hydrolysis of keratin hair conditioner of the invention, is made: hydrolysis of keratin 3%, water of the raw material of following percentage
Solve vegetable protein PG- propyl silane triol 1%, hydrolytic collagen 1%, collagenous amino acids 0.5%, glycerol 5%, the bent ammonium methyl in west
Sulfate 1.5%, cetostearyl alcohol 3%, panthenol 1.5%, behenyl base trimethylammoniumethyl sulfate 1%, quaternary ammonium salt -33
0.2%, guar hydroxypropyltrimonium chloride 0.2%, allantoin 0.2%, DMDM hydantoin 0.2%, EDETATE SODIUM
0.15%, essence 0.05%, surplus are deionized water.
The preparation method is the same as that of Example 1, and therefore not to repeat here.
Embodiment 3
A kind of hydrolysis of keratin hair conditioner of the invention, is made: hydrolysis of keratin 3%, water of the raw material of following percentage
Solve vegetable protein PG- propyl silane triol 2%, hydrolytic collagen 1.5%, collagenous amino acids 1%, glycerol 10%, the bent ammonium first in west
Base sulfate 3%, cetostearyl alcohol 2%, panthenol 1%, behenyl base trimethylammoniumethyl sulfate 1.5%, quaternary ammonium salt -33
0.3%, guar hydroxypropyltrimonium chloride 0.1%, allantoin 0.3%, DMDM hydantoin 0.3%, EDETATE SODIUM
0.3%, essence 0.2%, surplus are deionized water.
The preparation method is the same as that of Example 1, and therefore not to repeat here.
Embodiment 4
A kind of hydrolysis of keratin hair conditioner of the invention, is made: hydrolysis of keratin 4%, water of the raw material of following percentage
Solve vegetable protein PG- propyl silane triol 3%, hydrolytic collagen 2%, collagenous amino acids 1.5%, glycerol 8%, the bent ammonium methyl in west
Sulfate 2%, cetostearyl alcohol 2%, panthenol 2%, behenyl base trimethylammoniumethyl sulfate 2%, quaternary ammonium salt -33 0.2%,
Guar hydroxypropyltrimonium chloride 0.1%, allantoin 0.2%, DMDM hydantoin 0.4%, EDETATE SODIUM 0.3%, perfume
Essence 0.1%, surplus is deionized water.
The preparation method is the same as that of Example 1, and therefore not to repeat here.
Embodiment 5
A kind of hydrolysis of keratin hair conditioner of the invention, is made: hydrolysis of keratin 5%, water of the raw material of following percentage
Solve vegetable protein PG- propyl silane triol 3%, hydrolytic collagen 2%, collagenous amino acids 0.5%, glycerol 9%, the bent ammonium methyl in west
Sulfate 3%, cetostearyl alcohol 1%, panthenol 3%, behenyl base trimethylammoniumethyl sulfate 1%, quaternary ammonium salt -33 0.3%,
Guar hydroxypropyltrimonium chloride 0.1%, allantoin 0.3%, DMDM hydantoin 0.2%, EDETATE SODIUM 0.3%, perfume
Essence 0.15%, surplus is deionized water.
The preparation method is the same as that of Example 1, and therefore not to repeat here.
The hair care effect of the hair conditioner of the present invention of embodiment 6 is evaluated
Volunteer of 183 ages for selecting different regions, different hair qualitys, the hair quality extent of damage different in 18-45 one full year of life
Carry out clinical trial.It is randomly divided into experimental group and control group for volunteer by 95, wherein experimental group 1 is 32 people, uses the present invention
The hair conditioner product of embodiment 4;Control group 1 is 31 people, and using commercially available hair conditioner product, control group 2 is 32 people, does not use and appoints
What hair products;Experimental group uses corresponding hair conditioner product with control group respectively, is used continuously daily in the first week, second
It uses once within every two days after week, continues 28 days.Application method is as follows: after wet hair, suitable shampoo cleaning topknot is poured out,
Poured out after rinsing well the rubbing of appropriate hair conditioner it is several under be applied on scalp and hair again, gently rub a moment, then washed down with water.
After experimental period, collects 95 volunteers and use the toughness of hair quality, pliability, combing after corresponding hair conditioner
The evaluation of property, moisturizing degree.Evaluation index is divided into five grades, very satisfied 5 points, is satisfied with 4 points, general 3 points, is unsatisfied with 2 points, non-
It is often 1 point dissatisfied.The use scoring of volunteer is as follows, and average mark is higher, and to represent satisfaction higher.
The tough effect comparison table of the hair conditioner of the present invention of table 1.
The soft effect table of comparisons of the hair conditioner of the present invention of table 2.
The carding effect table of comparisons of the hair conditioner of the present invention of table 3.
The moistening effect table of comparisons of the hair conditioner of the present invention of table 4.
As seen from the above table, the hydrolysis of keratin hair conditioner of the embodiment of the present invention 4 is in the toughness of hair quality, pliability, combing
The satisfaction of property, moisturizing degree etc. is above commercial product and is not suitable for the effect of any hair products.And volunteer makes
With not occurring the phenomena of cutaneous irritation such as rubescent, dermexanthesis, blistering in the process.
The foregoing is merely better embodiments of the invention, and the invention is not limited to above embodiment, are implementing
The structural modification small there may be part in the process, if various changes or modifications of the invention are not departed from essence of the invention
Mind and range, and belong within the scope of claim and equivalent technologies of the invention, then the present invention is also intended to encompass these changes
And modification.
Claims (3)
1. a kind of hydrolysis of keratin hair conditioner, which is characterized in that be made of the raw material of following percentage: hydrolysis of keratin 2-5%,
Hydrolyzed vegetable protein PG- propyl silane triol 1-3%, hydrolytic collagen 1-3%, collagenous amino acids 0.5-2%, glycerol 5-
10%, the bent ammonium methyl sulphate 1-3% in west, cetostearyl alcohol 1-3%, panthenol 1-3%, behenyl base trimethylammoniumethyl sulfate
1-2%, quaternary ammonium salt -330.1-0.3%, guar hydroxypropyltrimonium chloride 0.1-0.3%, allantoin 0.1-0.3%,
DMDM hydantoin 0.2-0.4%, EDETATE SODIUM 0.1-0.3%, essence 0.05-0.2%, surplus are deionized water.
2. a kind of hydrolysis of keratin hair conditioner according to claim 1, which is characterized in that by the raw material system of following percentage
At: hydrolysis of keratin 4%, hydrolyzed vegetable protein PG- propyl silane triol 3%, hydrolytic collagen 2%, collagenous amino acids
1.5%, glycerol 8%, west bent ammonium methyl sulphate 2%, cetostearyl alcohol 2%, panthenol 2%, behenyl base trimethylammoniumethyl sulphur
Hydrochlorate 2%, quaternary ammonium salt -330.2%, guar hydroxypropyltrimonium chloride 0.1%, allantoin 0.2%, DMDM hydantoin
0.4%, EDETATE SODIUM 0.3%, essence 0.1%, surplus are deionized water.
3. a kind of method for preparing the described in any item hydrolysis of keratin hair conditioner of claim 1 to 2, it is characterised in that including such as
Lower step:
(1) first deionized water is added in emulsion pot, glycerol, panthenol, EDETATE SODIUM, allantois is successively added into emulsion pot
Element, guar hydroxypropyltrimonium chloride, quaternary ammonium salt -33 are stirred and heated to 75-80 DEG C, and constant temperature is made to being completely dissolved
First mixture;
(2) cetostearyl alcohol, the bent ammonium methyl sulphate in west, behenyl base trimethylammoniumethyl sulfate are added sequentially to oily phase again
In pot, oily phase pot is heated to 75-80 DEG C, the second mixture is made to being completely dissolved in constant temperature;
(3) the second mixture obtained in step (2) is pumped into the emulsion pot of step (1) again, emulsion pot constant temperature 75-80
DEG C, it is mixed slowly after homogeneous 5min and is cooled to 45 DEG C, obtained third mixture;
(4) protein hydrolysate, hydrolyzed vegetable protein PG- propyl silane triol, water are added into third mixture made from step (3)
Collagen, collagenous amino acids are solved, is stirred to uniformly mixed;Add DMDM hydantoin, essence, stirring is to being mixed thoroughly
?.
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CN110327248A (en) * | 2019-08-05 | 2019-10-15 | 广州优敏泉生物科技有限公司 | A kind of composition and manufacture craft of no silicone oil conditioning hair |
CN110638717A (en) * | 2019-10-09 | 2020-01-03 | 株洲千金药业股份有限公司 | Softening composition and shampoo thereof |
CN111467253A (en) * | 2020-04-14 | 2020-07-31 | 广东优博日化用品有限公司 | Hair care cosmetic and preparation method thereof |
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CN112587424A (en) * | 2020-12-18 | 2021-04-02 | 珠海伊斯佳科技股份有限公司 | A hair composition with effects of protecting color and hair, and its preparation method |
CN112618408A (en) * | 2021-01-14 | 2021-04-09 | 洋妆源(上海)网络科技有限公司 | Composite protein hair repair composition and application thereof |
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CN115252495B (en) * | 2022-08-11 | 2023-08-11 | 河南迷迭香生物科技有限公司 | Rosemary amino acid hair conditioner and preparation method thereof |
CN115531242A (en) * | 2022-10-24 | 2022-12-30 | 广州市圣莎拉化妆品有限公司 | Hair straightening and repairing composition |
CN116115514A (en) * | 2023-04-04 | 2023-05-16 | 广州美思生物技术有限公司 | Hair-care plant protein composition and preparation method and application thereof |
CN117426997A (en) * | 2023-12-20 | 2024-01-23 | 拉芳家化股份有限公司 | Hair restoration composition and application thereof |
CN117426997B (en) * | 2023-12-20 | 2024-04-02 | 拉芳家化股份有限公司 | Hair restoration composition and application thereof |
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