CN109452646A - A kind of Radix Astragali water and preparation method thereof - Google Patents
A kind of Radix Astragali water and preparation method thereof Download PDFInfo
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- CN109452646A CN109452646A CN201811258511.8A CN201811258511A CN109452646A CN 109452646 A CN109452646 A CN 109452646A CN 201811258511 A CN201811258511 A CN 201811258511A CN 109452646 A CN109452646 A CN 109452646A
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- water
- radix astragali
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- astragalus root
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to technical field of health care food, and in particular to a kind of Radix Astragali water and preparation method thereof.Radix Astragali water of the present invention includes the following raw material: Astragalus Root P.E, resistant dextrin, corn silk water boil liquid and water.Radix Astragali water component of the present invention is simple, safe to the human body harmless, has the function of blood pressure lowering outstanding, hypoglycemic.
Description
Technical field
The present invention relates to technical field of health care food, and in particular to a kind of Radix Astragali water and preparation method thereof.
Background technique
Hypertension is one of most important risk factor in the most common chronic disease and cardiovascular and cerebrovascular disease, can be caused
A variety of diseases such as coronary heart disease, cerebral apoplexy, congestive heart failure and renal dysfunction, morbidity and mortality have been more than tumprigenicity
Disease simultaneously leaps to the first.
Doctor trained in Western medicine thinks that the cause of disease of hypertension mainly includes inherent cause, spirit and environmental factor, age factor, life habit
Used factor, the influence of drug and other diseases influence, be now widely used for the drug such as captopril of blood pressure lowering, be depressured
Principle is exactly to inhibit the activity of ACE.It such as coughs however, taking artificial synthesized blood-pressure drug for a long time and often generating, is white thin
The toxic side effects such as born of the same parents' reduction, itch, fash, dizziness.There is no this names of disease of hypertension in Chinese medicine, according to the sick position of this disease of symptom
In clear key, cause brains hollow by deficiency of qi and blood, kidney essence deficiency, YANG-orifices failing to be nourished or liver-yang hyperactivity, convulsive seizure due to phlegm-fire superinverse, obstruction of the orifices by blood stasis and
It disturbs clear key and dizziness occurs, it is dirty in close relations with liver,spleen,kidney three.The characteristic of disease of dizziness is in the majority with empty person, therefore Zhang Jingyue calls " empty person
Occupy its eight or nine ", such as the deficiency of liver-yin and kidney-yin, liver wind agitation, deficiency of qi and blood, YANG-orifices failing to be nourished, deficiency of kidney-essence, brains mistake are filled.Dizziness real example is more
It is checked by phlegm is turbid, disturbance in ascending and descending, the convulsive seizure due to phlegm-fire circulation of vital energy in the wrong direction, upper to violate clear key, hemostasis is at a stop, and numbness hinders clear key and forms.
Prior art CN106923109A discloses one kind and disappears lipoid and reducing blood pressure beverage, is prepared from the following raw materials: Chinese medicinal decoction, fruit
Juice, vegetable juice, happy agent composition.The Chinese medicinal decoction is made of hawthorn, Radix Salviae Miltiorrhizae, corn stigma, lotus leaf mixing；The fruit syrup by
Apple, pawpaw, Chinese grooseberry, grape mixing composition；The vegetable juice is made of celery, balsam pear, garlic mixing.Above-mentioned offer
The lipoid and reducing blood pressure beverage that disappears has effects that reducing blood lipid, blood pressure, blood glucose, clearing heat and detoxicating, diuresis.However above-mentioned beverage, component is extremely complex,
Not only influence mouthfeel, the stability of product is also difficult to ensure, the interaction that generates between each ingredient is difficult to understand fully, and drops blood
Pressure, blood sugar decreasing effect be not significant.
Summary of the invention
It is an object of the invention to overcome in the prior art beverage ingredient complexity, blood pressure lowering, blood sugar decreasing effect it is poor, Jin Erti
It is simple for a kind of component, it is safe to the human body harmless, there is blood pressure lowering outstanding, the Radix Astragali water of hypoglycemic effect and its preparation side
Method.
In order to achieve the above objectives, the present invention adopts the following technical scheme:
A kind of Radix Astragali water, the raw material including following parts by weight: 5-30 parts of Astragalus Root P.E, 10-30 parts of resistant dextrin, corn
It must be 3-8 parts of water cooking liquid, 80-90 parts of water.
Preferably, the raw material including following parts by weight: 10-20 parts of Astragalus Root P.E, 15-20 parts of resistant dextrin, corn stigma
5-7 parts of water cooking liquid, 84-86 parts of water.
Preferably, the raw material including following parts by weight: 12 parts of Astragalus Root P.E, 18 parts of resistant dextrin, corn silk water boil liquid
6 parts, 85 parts of water.
It preferably, based on parts by weight further include 2-5 parts of extract of hypericum perforatum.
Preferably, the raw material including following parts by weight: 14 parts of Astragalus Root P.E, 19 parts of resistant dextrin, corn silk water boil liquid
5 parts, 3 parts of extract of hypericum perforatum, 86 parts of water.
Preferably, the Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8-10 times of parts by weight is added,
It decocts 2-4 times, obtains extracting solution, be concentrated after extracting solution filtering, it is dry, obtain Astragalus Root P.E.
Preferably, the Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts
3 times, extracting solution is obtained, is concentrated after extracting solution filtering, it is dry, obtain Astragalus Root P.E.
Preferably, the corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 8-12 times of parts by weight is added,
It impregnates 4-6 hours, decocts 1-3 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
Preferably, the corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 10 times of parts by weight is added, soaks
Bubble 5 hours decocts 2 hours, and decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
Preferably, the extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, 8-10 is added
The water of times parts by weight decocts 2-4 time, obtains extracting solution, is concentrated after extracting solution filtering, dries, obtain extract of hypericum perforatum.
Preferably, the extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, be added 9 times
The water of parts by weight decocts 3 times, obtains extracting solution, is concentrated after extracting solution filtering, dry, obtains extract of hypericum perforatum.
Preferably, the extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, be added 9 times
The water of parts by weight decocts 3 times, obtains extracting solution, is concentrated after extracting solution filtering, obtains concentrate, resistance malt is added into concentrate
Dextrin is uniformly mixed, and is ultrasonically treated in the aqueous citric acid solution that mass fraction is 3% after mixing, is filtered after ultrasonic treatment, is filtered
It is dry after liquid concentration, obtain extract of hypericum perforatum.
Preferably, the mass ratio of the Herba Hyperici Monogyni, resistant maltodextrin and citric acid is 1:0.2:0.3.
Preferably, the ultrasonic power is 500w, and ultrasonic temperature is 30 DEG C.
Preferably, the resistant dextrin is resistant maltodextrin.
Preferably, the water is underground water.
The present invention also provides a kind of preparation methods of Radix Astragali water described above, comprising the following steps:
1) Astragalus Root P.E and resistant dextrin are taken, is dissolved in water, the stirring of corn silk water boil liquid is added, filtering obtains filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Preferably, the preparation method of the Radix Astragali water, comprising the following steps:
1) Astragalus Root P.E, extract of hypericum perforatum and resistant dextrin are taken, is dissolved in water, corn silk water boil liquid is added and stirs
It mixes, filters, obtain filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Radix Astragali water of the present invention can the forms such as bottled, canned, Lile packaging, plastics package packed.
Radix Astragali water of the present invention can be used for it is daily drinking, hot plate food, be suitable for crowd used.
Astragalus Root P.E of the present invention can be prepared into powder or particle.
The effect of Radix Astragali: Radix Astragali is sweet in flavor, warm-natured；Return lung, the spleen channel, tonifying Qi and lifting yang, strengthening exterior and reducing sweat, detumescence and promoting granulation are Chinese medicines
Common tonifying Qi drug in prescription, can be with the gas of completion body.Chemical component mainly has flavonoids, polysaccharide, saponins and more
Kind amino acid and microelement.Modern pharmacological research is concentrated mainly on following several respects: protection myocardial damage adjusts blood pressure, increases
Heart tonifying myotility improves hemorheological property, adjusts the effects of immunity of organism, hypoglycemic, antitumor, antibacterial.
The effect of corn stigma: corn stigma contains kryptoxanthin (cryptoxan-thin), pantothenic acid (pantothenic acid),
Inositol (inositol), sitosterol (sitosterol), stigmasterol (stigmasterol), vitamin C, K, malic acid
(malic acid), citric acid (citric acid), oxalic acid (oxalic acid), tartaric acid (tartaric acid).Also contain
Fat oil, volatile oil, natural gum, resin, bitter taste glucosides, saponin(e, alkaloid and a large amount of potassium nitrate, Ipotensil (α-toco-
Pheryl quinone) etc..Chinese medicine corn stigma has the function of decompression, hypoglycemic, reducing blood lipid, diuresis, cholagogue, while studying table
Bright low dose corn stigma decoction has excitation to toad isolated heart, is in inhibiting effect when large dosage of.There are also certain for corn stigma
Anastalsis, it is effective to blood coagulation disorders caused by vitamin K deficiency.
The effect of resistant dextrin: resistant dextrin is a kind of white or pale yellow powder, soluble easily in water, heat-resisting, acidproof, cold-resistant
Freeze.The total dietary fiber of resistant dextrin is up to 82%, is a kind of soluble food raw material low in calories.Resistant dextrin has
Anti- digestive ferment action characteristic can be directly entered large intestine due to that will not be digested absorption in alimentary canal, and therefore, it is played
The various physiological actions of dietary fiber, because its height digestion tolerance, low-glycemic, low insulin index, low in calories, readily soluble
The characteristics such as solution, the effects of hypoglycemic, reducing blood lipid can be played and conserve enteron aisle.Resistant dextrin is not absorbed, instead by human body intestinal canal
In beneficial microbe utilize, stimulation growth of probiotics, breeding, inhibit harmful intestinal tract microorganism, for human body be provided with benefit tune
Substance is saved, immune system and function of intestinal canal are improved.
The effect of Herba Hyperici Monogyni: Herba Hyperici Monogyni is a kind of five perennial herbaceous plant of valve chrysanthemum, main product in North America,
Europe and Asia, are traditional one of the Chinese medicines in China.Contain naphthalene a pair of horses going side by side dianthrone compound, flavonoids in Herba Hyperici Monogyni
Close object and gamboge phenol derivatives.Its naphthalene a pair of horses going side by side dianthrone compound mainly includes hypericin, pseudohypericin, there are also former gold
Silk peach element and former pseudohypericin.Flavone compound mainly includes Hyperoside, quercitin, rutin, Quercetin and former flower
Green element etc..Gamboge phenol derivatives mainly have hyperforine and add hypericin when passing through.Traditional chinese medicine thinks, property
Flat, acrid flavour is bitter, has the effect of improving eyesight that clears away heart-fire, relax through promoting blood circulation, hemostasia and promoting granulation, detoxicating, relieving inflammation, dampness removing.
The invention has the advantages that:
1, Radix Astragali water of the present invention is using Astragalus Root P.E, corn silk water boil liquid, resistant dextrin as main composition,
Component is simple, safe to the human body harmless, has the function of blood pressure lowering outstanding, hypoglycemic.Astragalus Root P.E of the present invention is
Complete decocting preparation, meets traditional application method, remains the principle active component in Radix Astragali.Corn silk water is added in the present invention
Boil liquid, resistant dextrin not only make the sense of the Radix Astragali mouth of a river more preferable, while also effectively enhancing that Radix Astragali water is hypoglycemic, effect of blood pressure lowering.
Radix Astragali water dose of the present invention is controllable, main component is clear, on the basis that the original effect of Radix Astragali is completely secured
On, so that dose is reduced effect increase.
2, Astragalus Root P.E during the preparation process, by multiple boiling, smart filtering technique, reaches extract energy in the present invention
Dissolution rapidly in water, no precipitating and residual miscellaneous is transparent faint yellow, slightly sweet, especially eliminates the intrinsic beans raw meats soil of Radix Astragali
Taste can make consumer be easy to receive in the case where not adding any flavoring agent.
3, wet concentration of the present invention is located at the Northeast, Inner Mongol Huhehaote City from groundwater quality, is in alkalescent, contains
There are 20 various trace elements and minerals, without harmful substances such as arsenic, mercury, cadmium, silver and fluorine.
4, Astragalus Root P.E, corn silk water boil liquid, resistant dextrin, extract of hypericum perforatum, four kinds of components in the present invention
It cooperates, there is significant synergistic function, outstanding behaviours goes out blood pressure lowering, hypoglycemic effect.
5, extract of hypericum perforatum of the present invention is obtained using the method that water mentions, and safety and environmental protection will preferably pass through leaf
The water extracting liquid of Hypericum Chinense is mixed with resistant maltodextrin, and is ultrasonically treated in aqueous citric acid solution, and inventor's discovery can
To further increase blood pressure lowering, the hypoglycemic effect of Radix Astragali water.
Specific embodiment
There is provided following embodiments is to preferably further understand the present invention, it is not limited to the best embodiment party
Formula is not construed as limiting the contents of the present invention and protection scope, anyone under the inspiration of the present invention or by the present invention and its
The feature of his prior art is combined and any and identical or similar product of the present invention for obtaining, all falls within of the invention
Within protection scope.
Specific experiment step or condition person are not specified in embodiment, according to the literature in the art described routine experiment
The operation of step or condition can carry out.Reagents or instruments used without specified manufacturer, being can be by commercially available acquisition
Conventional reagent product.
Embodiment 1
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 5g, resistant maltodextrin 30g, corn silk water boil liquid 3g,
Water 90g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 2 times, often
Secondary is 1 hour, combined extract, and filtering is dry to be concentrated after removing water-insoluble materials, obtains Astragalus Root P.E.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 8 times of parts by weight is added, impregnates 4 hours,
It decocts 3 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E and resistant maltodextrin are taken, is dissolved in water, the stirring of corn silk water boil liquid is added, filtering must filter
Liquid；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Embodiment 2
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 30g, resistant maltodextrin 10g, corn silk water boil liquid
8g, water 80g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 10 times of parts by weight is added, decocts 4 times, often
Secondary is 3 hours, combined extract, and filtering is dry to be concentrated after removing water-insoluble materials, obtains Astragalus Root P.E.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 12 times of parts by weight is added, impregnates 6 hours,
It decocts 1 hour, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E and resistant maltodextrin are taken, is dissolved in water, the stirring of corn silk water boil liquid is added, filtering must filter
Liquid；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Embodiment 3
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 12g, resistant maltodextrin 18g, corn silk water boil liquid
6g, water 85g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 3 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 10 times of parts by weight is added, impregnates 5 hours,
It decocts 2 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E and resistant maltodextrin are taken, is dissolved in water, the stirring of corn silk water boil liquid is added, filtering must filter
Liquid；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Embodiment 4
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 10g, resistant maltodextrin 15g, corn silk water boil liquid
7g, water 86g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 9 times of parts by weight is added, decocts 3 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take 10g corn stigma, the water of 110g is added, impregnates 5 hours, decocts
It boils 2 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E and resistant maltodextrin are taken, is dissolved in water, the stirring of corn silk water boil liquid is added, filtering must filter
Liquid；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Embodiment 5
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 20g, resistant maltodextrin 20g, corn silk water boil liquid
5g, water 84g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 2 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take 5g corn stigma, the water of 60g is added, impregnates 4 hours, decocts 2
Hour, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E and resistant maltodextrin are taken, is dissolved in water, the stirring of corn silk water boil liquid is added, filtering must filter
Liquid；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Embodiment 6
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 10g, resistant maltodextrin 20g, corn silk water boil liquid
5g, extract of hypericum perforatum 2g, water 86g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 2 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 8 times of parts by weight is added, impregnates 4 hours,
It decocts 2 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, 8 times of parts by weight are added
Water decocts 2 times, is every time 2 hours, combined extract, extracting solution initial filter, and refined filtration is done with being concentrated after removing water-insoluble materials
It is dry, obtain extract of hypericum perforatum.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E, extract of hypericum perforatum and resistant maltodextrin are taken, is dissolved in water, corn stigma boiling is added
Liquid stirring, filtering obtain filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Embodiment 7
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 20g, resistant maltodextrin 15g, corn silk water boil liquid
7g, extract of hypericum perforatum 5g, water 84g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 10 times of parts by weight is added, decocts 4 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 12 times of parts by weight is added, impregnates 6 hours,
It decocts 3 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, 10 times of parts by weight are added
Water, decoct 4 times, be every time 3 hours, combined extract, extracting solution initial filter, refined filtration to be concentrated after removing water-insoluble materials,
It is dry, obtain extract of hypericum perforatum.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E, extract of hypericum perforatum and resistant maltodextrin are taken, is dissolved in water, corn stigma boiling is added
Liquid stirring, filtering obtain filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Embodiment 8
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 14g, resistant maltodextrin 19g, corn silk water boil liquid
5g, extract of hypericum perforatum 3g, water 86g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 3 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 10 times of parts by weight is added, impregnates 5 hours,
It decocts 2 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, 9 times of parts by weight are added
Water decocts 3 times, is every time 2 hours, combined extract, extracting solution initial filter, and refined filtration is done with being concentrated after removing water-insoluble materials
It is dry, obtain extract of hypericum perforatum.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E, extract of hypericum perforatum and resistant maltodextrin are taken, is dissolved in water, corn stigma boiling is added
Liquid stirring, filtering obtain filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Embodiment 9
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 14g, resistant maltodextrin 19g, corn silk water boil liquid
5g, extract of hypericum perforatum 3g, water 86g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 3 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 10 times of parts by weight is added, impregnates 5 hours,
It decocts 2 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, 9 times of parts by weight are added
Water decocts 3 times, is every time 2 hours, combined extract, extracting solution initial filter, and refined filtration is obtained with being concentrated after removing water-insoluble materials
Resistant maltodextrin is added into concentrate for concentrate, is uniformly mixed, water-soluble for 3% citric acid in mass fraction after mixing
It is ultrasonically treated in liquid, is filtered after ultrasonic treatment, it is dry after filtrate concentration, obtain extract of hypericum perforatum.It is described to pass through leaf spun gold
The mass ratio of peach, resistant maltodextrin and citric acid is 1:0.2:0.3；The ultrasonic power is 500w, ultrasonic temperature 30
℃。
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E, extract of hypericum perforatum and resistant maltodextrin are taken, is dissolved in water, corn stigma boiling is added
Liquid stirring, filtering obtain filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Comparative example 1
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 14g, resistant maltodextrin 19g, Radix Salviae Miltiorrhizae water cooking liquid 5g are passed through
Leaf perforatum extract 3g, water 86g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 3 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The Radix Salviae Miltiorrhizae water cooking liquid the preparation method is as follows: take Radix Salviae Miltiorrhizae, the water of 10 times of parts by weight is added after crushing, it is small to impregnate 5
When, it decocts 2 hours, decoction liquor filtering, obtaining filtrate is Radix Salviae Miltiorrhizae water cooking liquid.
The extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, 9 times of parts by weight are added
Water decocts 3 times, is every time 2 hours, combined extract, extracting solution initial filter, and refined filtration is done with being concentrated after removing water-insoluble materials
It is dry, obtain extract of hypericum perforatum.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E, extract of hypericum perforatum and resistant maltodextrin are taken, is dissolved in water, Radix Salviae Miltiorrhizae water cooking liquid is added
Stirring, filtering, obtains filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Comparative example 2
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 14g, resistant maltodextrin 19g, corn silk water boil liquid
5g, Prunella vulgaris extract 3g, water 86g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 3 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 10 times of parts by weight is added, impregnates 5 hours,
It decocts 2 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The Prunella vulgaris extract the preparation method is as follows: take the Prunella vulgaris of drying, the water of 9 times of parts by weight is added, decocts
3 times, be 2 hours every time, and combined extract, extracting solution initial filter, refined filtration is dry to be concentrated after removing water-insoluble materials, obtains
Prunella vulgaris extract.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E, Prunella vulgaris extract and resistant maltodextrin are taken, is dissolved in water, corn silk water boil liquid is added and stirs
It mixes, filters, obtain filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Comparative example 3
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 14g, resistant maltodextrin 19g, corn silk water boil liquid
5g, extract of hypericum perforatum 3g, water 86g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 3 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 10 times of parts by weight is added, impregnates 5 hours,
It decocts 2 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, 9 times of parts by weight are added
Water decocts 3 times, is every time 2 hours, combined extract, extracting solution initial filter, and refined filtration is obtained with being concentrated after removing water-insoluble materials
Concentrate, concentrate are ultrasonically treated in the aqueous citric acid solution that mass fraction is 3%, filter after ultrasonic treatment, filtrate concentration
After dry, obtain extract of hypericum perforatum.The mass ratio of the Herba Hyperici Monogyni and citric acid is 1.2:0.3；The ultrasound
Power is 500w, and ultrasonic temperature is 30 DEG C.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E, extract of hypericum perforatum and resistant maltodextrin are taken, is dissolved in water, corn stigma boiling is added
Liquid stirring, filtering obtain filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Comparative example 4
A kind of Radix Astragali water, including the following raw material: Astragalus Root P.E 14g, resistant maltodextrin 19g, corn silk water boil liquid
5g, extract of hypericum perforatum 3g, water 86g.
The Astragalus Root P.E the preparation method is as follows: take Radix Astragali medicine materical crude slice, the water of 8 times of parts by weight is added, decocts 3 times, often
Secondary is 2 hours, combined extract, extracting solution initial filter, and refined filtration is dry to be concentrated after removing water-insoluble materials, obtains Radix Astragali and mentions
Take object.
The corn silk water boil liquid the preparation method is as follows: take corn stigma, the water of 10 times of parts by weight is added, impregnates 5 hours,
It decocts 2 hours, decoction liquor filtering, obtaining filtrate is corn silk water boil liquid.
The extract of hypericum perforatum the preparation method is as follows: take the Herba Hyperici Monogyni of drying, 9 times of parts by weight are added
Water decocts 3 times, is every time 2 hours, combined extract, extracting solution initial filter, and refined filtration is obtained with being concentrated after removing water-insoluble materials
Resistant maltodextrin is added into concentrate for concentrate, is uniformly mixed, the aqueous acetic acid for being 3% in mass fraction after mixing
Middle ultrasonic treatment filters after ultrasonic treatment, dry after filtrate concentration, obtains extract of hypericum perforatum.The Herba Hyperici Monogyni,
The mass ratio of resistant maltodextrin and acetic acid is 1:0.2:0.3；The ultrasonic power is 500w, and ultrasonic temperature is 30 DEG C.
The preparation method of the Radix Astragali water, steps are as follows:
1) Astragalus Root P.E, extract of hypericum perforatum and resistant maltodextrin are taken, is dissolved in water, corn stigma boiling is added
Liquid stirring, filtering obtain filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
Comparative example 5
Astragalus Root P.E group: it is mixed that 86g water is added in the Astragalus Root P.E 41g being prepared by the method in embodiment 8
It is even.Corn silk water boil liquid group: the corn silk water boil liquid 41g being prepared by the method in embodiment 8 is added 86g water and mixes.
Resistant maltodextrin group: resistant maltodextrin 41g is added 86g water and mixes.
Extract of hypericum perforatum group: the extract of hypericum perforatum 41g being prepared by the method in embodiment 8,
86g water is added to mix.
Application test example
The influence of pair spontaneous hypertensive rat 1. (SHR) blood pressure
SHR rat 130 are taken, half male and half female surveys basic blood pressure, experiment using arteria caudalis indirect method after conventinal breeding 1 week
There was no significant difference between preceding each group rat, and each group basic blood pressure value is uniform.Test rat is randomly divided into 12 groups, every group 10,
Be divided into model control group and test group, test group include Astragalus Root P.E group, corn silk water boil liquid group, resistant maltodextrin group,
Extract of hypericum perforatum group and 3 groups of embodiment, 8 groups of embodiment, 9 groups of embodiment, comparative example 1-4 group.Get 10 wky
Rat is as Normal group.Each test group feeds corresponding tested material, 1ml/100g, and 1 times/day, continuous 30 days, normal control
Group and model control group under equal conditions give distilled water.Respectively 15 days after gavaging, the record big rat-tail of each group of measurement in 30 days it is dynamic
Arteries and veins systolic pressure.As a result it is examined using comparison among groups t and carries out statistical procedures.
Table 1 is as the result is shown: wky control group blood pressure held stationary state during test；Model control group blood pressure, which is presented, to be continued
Ascendant trend has significant difference (P < 0.01) compared with Normal group；After tested material, the blood pressure of embodiment group occurs
Apparent decline.The antihypertensive effect of the embodiment of the present invention is substantially better than the Astragalus Root P.E group being administered alone, corn silk water boil liquid
Group, resistant maltodextrin group, extract of hypericum perforatum group.Illustrate Astragalus Root P.E group, corn silk water boil liquid group, resistance malt
Four kinds of dextrin group, extract of hypericum perforatum group components have significant synergistic function.It can be with by comparative example 3 and 4
Find out, the present invention cleverly utilizes resistant maltodextrin when preparing extract of hypericum perforatum, and surpasses in citric acid solution
Sonication effectively enhances the antihypertensive effect of Radix Astragali water.
Influence unit of the table 1 to SHR rat systolic pressure: mmHg
Compared with wky control group:#P<0.05##P<0.01；Compared with model control group:*P<0.05**P<0.01
2. the influence pair Renovascular hypertension rat blood pressure
Healthy Wister rat, half male and half female are taken, operation consent arteria caudalis surveys basic blood pressure, heart rate, determines in normal range (NR)
Afterwards, yellow Jackets press 4mg/100g dosage intraperitoneal injection of anesthesia, face upward position and fix, sterile working lower abdomen median incision, separation
Left renal artery causes renal artery stenosis, right side kidney through clamping the arteria renalis for the self-control artery clamp of 0.2mm with interior at nearly hilus renalis end
It is dirty not touch.It is then shut off abdominal cavity.It takes 10 rats only to open abdomen simultaneously but does not do arteria renalis operation as Sham-operated control group.
Start to survey arteria caudalis blood pressure after postoperative 2nd week, once a week, continuous 2 weeks, blood pressure is selected to rise 40mmHg or more compared with basic blood pressure
Rat be considered as modeling and be used successfully to test.Modeling success rats are divided into 6 groups by mean value of blood pressure, make every group of rat blood pressure
Average almost the same, every group 10, respectively model control group and test group, test group include Astragalus Root P.E group, corn stigma
Water cooking liquid group, resistant maltodextrin group, extract of hypericum perforatum group and 9 groups of embodiment.Separately take 10 it is without any processing
Rat is as Normal group.
Test group stomach-filling tested material, each 1ml/100g, 1 time a day, and continuous 20 days, Normal group, sham-operation control
Group and model control group under equal conditions give distilled water.Rat tail artery systolic pressure is measured after 20 days, carries out abdomen after measurement
Aorta takes blood, for measuring vaso-active substance, relevant ions.
Table 2 is as the result is shown: Normal group and sham-operation group blood pressure are steadily in normal condition during test；It is respectively tried after modeling
It tests group blood pressure to increase, have compared with sham-operation group significant difference (P < 0.05, P < 0.01), but indifference between each group, explanation
Modeling success；9 groups of blood pressures of embodiment are substantially reduced after administration 20 days.Illustrating 9 groups of embodiment has significant antihypertensive effect, and drops
Pressure effect is far superior to Astragalus Root P.E group, the corn silk water boil liquid group, resistant maltodextrin group, Herba Hyperici Monogyni being administered alone
Extract group.
Table 3 is as the result is shown: 9 groups of embodiment to Na+, K+, Ca++ in Renovascular hypertension rat blood serum without obvious
It influences.
Influence unit of the table 2 to renal artery stenosis rat blood pressure: mmHg
Compared with sham-operation group#P<0.05##P<0.01
P < 0.05**P < 0.01 * compared with model control group
Table 3 is to the influence unit in Stenosis of Renal Artery Caused Hypertension in Mice serum in relation to ion concentration: mmol/L
3. on streptozotocin (STZ)) cause rat diabetes model to influence
3.1 groupings and modeling
SD rat 150 are taken, adaptive feeding 1 week, 8 is left and taken at random and is only used as Normal group, remaining animal is made
Mould.After animal fasting 12h, by 60mg/kg weight, the disposable injection concentration in abdominal cavity is the STZ of 10mg/ml, Normal group note
Penetrate isometric citrate buffer.After Normal group and test group are injected 7 days, the equal eye socket of animal takes blood, with grape glycosyloxy
Chemical-enzyme method survey fasting 12h blood glucose, using blood sugar concentration 9.0-13.0mmol/L be modeling successfully animal.
The successful animal of modeling is randomly divided into 10 groups, i.e. model control group and test group, test group includes that Radix Astragali mentions
Take object group, corn silk water boil liquid group, resistant maltodextrin group, extract of hypericum perforatum group, embodiment 1-3 group, embodiment 8
9 groups of group, embodiment, every group 8.It is primary to tested material to test the daily stomach-filling of each group, 1ml/100g, successive administration 14 days, normally
Control group and model control group give same volume distilled water, and Normal group and rats in test groups feed normal diet during administration,
Normal water, feed and drinking-water are unrestricted.
3.2 Testing index
After administration 7 days, 14 days, femoral artery takes blood, surveys blood glucose in serum.Test the data obtained uses X ± SD table
Show, comparison among groups t is examined.
3.3 test result
Influence (unit: mmol/L) of the table 4 to Diabetic Model of Rats Induced by Streptozotocin blood glucose
Note: compared with Normal group##P<0.01；Compared with model control group, P < 0.01 * *；*P<0.05
Table 4 is as the result is shown: Normal group during entire test blood glucose value steadily in normal range (NR)；Model control group examination
Blood glucose, with significant difference (P < 0.01) compared with Normal group, shows modeling success steadily in required range during testing.
Astragalus Root P.E group, corn silk water boil liquid the group 2 weeks blood glucose after stomach-filling are remarkably decreased, and have significant difference compared with model group
(P<0.05).Embodiment group blood glucose since stomach-filling the 1st week is remarkably decreased, have compared with model group significant difference (P <
0.01).Illustrate embodiment group hypoglycemic effect better than independent stomach-filling group.Astragalus Root P.E, corn silk water boil liquid, resistance malt paste
Four kinds of essence, extract of hypericum perforatum components mutual cooperations have significant synergistic function, and outstanding behaviours goes out to reduce blood
The effect of sugar.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or
It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or
It changes still within the protection scope of the invention.
Claims (10)
1. a kind of Radix Astragali water, which is characterized in that the raw material including following parts by weight: 5-30 parts of Astragalus Root P.E, resistant dextrin 10-
30 parts, 3-8 parts of corn silk water boil liquid, 80-90 parts of water.
2. Radix Astragali water according to claim 1, which is characterized in that the raw material including following parts by weight: Astragalus Root P.E 10-
20 parts, 15-20 parts of resistant dextrin, 5-7 parts of corn silk water boil liquid, 84-86 parts of water.
3. Radix Astragali water according to claim 1 or 2, which is characterized in that the raw material including following parts by weight: Astragalus Root P.E
12 parts, 18 parts of resistant dextrin, 6 parts of corn silk water boil liquid, 85 parts of water.
4. Radix Astragali water according to claim 1 to 3, which is characterized in that the preparation method of the Astragalus Root P.E
It is as follows: to take Radix Astragali medicine materical crude slice, the water of 8-10 times of parts by weight is added, decoct 2-4 times, obtain extracting solution, be concentrated, do after extracting solution filtering
It is dry, obtain Astragalus Root P.E.
5. Radix Astragali water according to any one of claims 1-4, which is characterized in that the preparation method of the Astragalus Root P.E
It is as follows: Radix Astragali medicine materical crude slice is taken, the water of 8 times of parts by weight is added, is decocted 3 times, extracting solution is obtained, is concentrated after extracting solution filtering, it is dry, it obtains
Astragalus Root P.E.
6. Radix Astragali water described in -5 any one according to claim 1, which is characterized in that the preparation side of the corn silk water boil liquid
Method is as follows: taking corn stigma, the water of 8-12 times of parts by weight is added, impregnate 4-6 hours, decoct 1-3 hours, decoction liquor filtering must filter
Liquid is corn silk water boil liquid.
7. Radix Astragali water described in -6 any one according to claim 1, which is characterized in that the preparation side of the corn silk water boil liquid
Method is as follows: taking corn stigma, the water of 10 times of parts by weight is added, impregnate 5 hours, decoct 2 hours, decoction liquor filtering, obtaining filtrate is
Corn silk water boil liquid.
8. Radix Astragali water described in -7 any one according to claim 1, which is characterized in that the resistant dextrin is resistance malt paste
Essence.
9. Radix Astragali water according to any one of claims 1 to 8, which is characterized in that the water is underground water.
10. a kind of preparation method of Radix Astragali water described in any one of claim 1-9, which comprises the following steps:
1) Astragalus Root P.E and resistant dextrin are taken, is dissolved in water, the stirring of corn silk water boil liquid is added, filtering obtains filtrate；
2) remaining water is added into filtrate, obtains the Radix Astragali water.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1237433A (en) * | 1998-06-03 | 1999-12-08 | 杨学忠 | Chinese medicine prescription and its preparation method |
| CN101264122A (en) * | 2007-03-16 | 2008-09-17 | 中国医学科学院药物研究所 | Hypericum extract, its making method and medicinal composition and use for treating diabetes |
| CN105902857A (en) * | 2016-05-25 | 2016-08-31 | 中国科学院寒区旱区环境与工程研究所 | Astragalus membranaceus, corn stigma and wolfberry fruit hypoglycemic oral liquid and preparation method thereof |
| CN106666312A (en) * | 2017-01-11 | 2017-05-17 | 大连雅威特生物技术股份有限公司 | Health-care food for assisting blood glucose decreasing and preparation method of granule and capsule thereof |
-
2018
- 2018-10-26 CN CN201811258511.8A patent/CN109452646A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1237433A (en) * | 1998-06-03 | 1999-12-08 | 杨学忠 | Chinese medicine prescription and its preparation method |
| CN101264122A (en) * | 2007-03-16 | 2008-09-17 | 中国医学科学院药物研究所 | Hypericum extract, its making method and medicinal composition and use for treating diabetes |
| CN105902857A (en) * | 2016-05-25 | 2016-08-31 | 中国科学院寒区旱区环境与工程研究所 | Astragalus membranaceus, corn stigma and wolfberry fruit hypoglycemic oral liquid and preparation method thereof |
| CN106666312A (en) * | 2017-01-11 | 2017-05-17 | 大连雅威特生物技术股份有限公司 | Health-care food for assisting blood glucose decreasing and preparation method of granule and capsule thereof |
Non-Patent Citations (2)
| Title |
|---|
| 张泽生等: "抗性糊精对小鼠血糖及糖耐量的影响", 《食品科技》 * |
| 杨庆辉等: "抗焦虑抑郁药物对高血压治疗作用的临床研究", 《心血管康复医学杂志》 * |
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