CN109431846A - A kind of bioactive ingredients skin care item - Google Patents
A kind of bioactive ingredients skin care item Download PDFInfo
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- CN109431846A CN109431846A CN201811436494.2A CN201811436494A CN109431846A CN 109431846 A CN109431846 A CN 109431846A CN 201811436494 A CN201811436494 A CN 201811436494A CN 109431846 A CN109431846 A CN 109431846A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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Abstract
The present invention provides a kind of bioactive ingredients skin care item, including following components in percentage by weight: biological active component 0.1-0.3%, water chestnut extract 4-8%, matrix components 20-24%, surplus are water；The biological active component consists of the following components in percentage by weight: wheat peptide 0.04-0.13%, oat peptide 0.02-0.07%, -1 0.02-0.05% of palmityl tripeptides, -10 0.01-0.05% of palmityl tetrapeptide.Bioactive skin protection product good penetrability provided by the invention easily absorbs, and clearly not sticky using rear face, moisturizing, moistening effect are good, effectively calms down microgroove, reduces wrinkle, slowing down skin aging, and long-acting moisturizing, keeps skin water profit smooth, flexible.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of bioactive ingredients skin care item and preparation method.
Background technique
It is puberty, the skin slip of women, gloss, plentiful, high resilience, white touched with red.To after 35 years old, new old generation
Thank and start to slow down, moisture and subcutaneous fat are reduced, and hormone in vivo dysequilibrium, cutis laxa, coarse, wrinkle increase, gradually into
Enter aging period.Skin aging is the outstanding behaviours of entire body aging, and wherein facial skin aging is particularly evident, and wrinkle also starts
Gradually generate.
Skin aging by objective factors such as age, heredity other than being influenced, also by many factors such as daylight, environment, health
It influences；It is lived in seriously polluted environment for a long time or excessive contact is to the harmful chemical substance of skin, can all make skin damage,
Accelerated ageing；Malnutrition, is eaten up with illness at lassitude, and skin is easier to premature aging；Modern life pressure is big, and overtime work is endured
Night, for a long time to computer, smoking, sleep insufficiency, for a long time stay in air-conditioned room, drink, excess eye-using etc. becomes life normality,
So that the trend to become younger is presented in skin ageing phenomenon.
Although skin aging is irreversible physiological phenomenon, its process can delay or slow down.For face wrinkles,
Smoothing wrinkle of performing the operation and injection anti-wrinkle treatment cost height, risk are big, and moisturizing and anti-wrinkle cosmetic are a selections well.
Therefore, it is necessary to research and develop a kind of long-acting moisturizing, keep skin smooth flexible, effectively calm down wrinkle of skin, inhibits wrinkle
Line regeneration, the skin care item of delay skin aging.
Summary of the invention
Of the invention provides a kind of long-acting moisturizing, keeps skin smooth flexible, effectively calms down wrinkle of skin, inhibits wrinkle
Regeneration, the skin care item of delay skin aging.
A kind of bioactive ingredients skin care item, including following components in percentage by weight: biological active component 0.1-0.3%,
Water chestnut extract 4-8%, matrix components 20-24%, surplus are water.
Preferably, a kind of bioactive ingredients skin care item, the biological active component, by the group of following weight percent
It is grouped as: wheat peptide 0.04-0.13%, oat peptide 0.02-0.07%, -1 0.02-0.05% of palmityl tripeptides, palmityl tetrapeptide -
10 0.01-0.05%。
It is further preferred that a kind of bioactive ingredients skin care item, the biological active component, by following weight percent
The group of ratio is grouped as: wheat peptide 0.05-0.10%, oat peptide 0.02-0.045%, -1 0.02-0.038% of palmityl tripeptides, palm fibre
- 10 0.01-0.036% of palmitic acid acyl tetrapeptide.
In some embodiments of the invention, a kind of bioactive ingredients skin care item, the biological active component, by with
The group of lower weight percent is grouped as: wheat peptide 0.084%, oat peptide 0.034%, palmityl tripeptides -1 0.026%, palmityl
Tetrapeptide -10 0.036%.
In other embodiments of the invention, a kind of bioactive ingredients skin care item, the biological active component by
Following components in percentage by weight composition: wheat peptide 0.076%, oat peptide 0.042%, palmityl tripeptides -1 0.031%, palm
Acyl tetrapeptide -10 0.021%.
In the present invention, palmityl tripeptides -1, palmityl tetrapeptide -10 are fat-soluble strong, can preferably be absorbed by the skin, and enhance face
Portion's elasticity, promotes cell activity, has apparent regulation and facilitation to skin cell renewal, reparation, collagen synthesis.
Oat peptide has the function of anti-oxidant, removing free radical；Increase the collagen content in skin；Accelerate cell Proliferation and new old
Metabolism；Reduce skin roughness, the effect of Cucumber Extract.Wheat peptide has the work for improving moisture content of skin, playing moisturizing factor
With can soften skin, lock moisture of skin, assign skin and moisten.
In above-mentioned bioactive ingredients skin care item, the water chestnut extract can be prepared by conventional alcohol extracting method,
It is preferred that prepared by following methods:
(1) preparation of water chestnut extract -1: water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, 12-20 times of its weight is added
Deionized water is boiled 2-3 hours, is collected the gas of evaporation, is condensed, obtains volatilization liquid；It will volatilize liquid be concentrated, be spray-dried, obtaining
To water chestnut extract -1.
(2) water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces by the preparation of water chestnut extract 2, its weight 15-30 is added
Extracting solution concentration, spray drying are obtained water chestnut by 75% ethanol solution again, extract return method 2-3 times, filtering, combined extract
Shepherd's purse extract -2.
Preferably, in above-mentioned bioactive ingredients skin care item, the water chestnut extract is mentioned by water chestnut extract 1 and water chestnut
2 component of object is taken, wherein -1 1.2-2.7% of water chestnut extract, -2 3-5.3% of water chestnut extract；It is preferred that water chestnut extract -1
1.5%, water chestnut extract -2 4.2%.
In above-mentioned bioactive ingredients skin care item, the matrix components are consisted of the following components in percentage by weight: cream
Agent 4-5%；Moisturizer 6 ~ 10%, emollient 7 ~ 9%, thickener 0.5-1%, preservative 0.1 ~ 0.2%, essence 0.1 ~ 0.3%, essence
Propylhomoserin 0.01 ~ 0.5%.
The emulsifier is selected from cetanol palmitate, stearine, tribehenin essence PEG-20 esters, polyglycereol -3
One of diisopstearate, cetostearyl alcohol olive oleate, the smooth palmitate of sorb, the smooth olive oleate of sorb or two
Kind combination of the above, the preferably group of three kinds of the smooth olive oleate of cetostearyl alcohol olive oleate, sorb, smooth palmitate of sorb etc.
Close object.
The thickener is hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers.
The emollient is cyclomethicone, tocopherol acetate, PEG-10 dimethyl silicone polymer/ethylene
The combination of one or more of base Dimethicone Crosspolymer, preferably cyclomethicone, tocopherol
The composition of three kinds of acetic acid esters, PEG-10 Dimethicone/Vinyl Dimethicone cross-linked polymer etc..
The moisturizer is selected from glycerol, butanediol, propylene glycol, glycerol acrylic acid/acrylic copolymer, glycine betaine, transparent
The combination of one or more of matter acid sodium, trehalose；Preferably glycerine, butanediol, propylene glycol, glycerol acrylic acid/acrylic acid
The composition that five kinds of copolymer, Sodium Hyaluronate etc..
The preservative is in methyl hydroxybenzoate, Nipasol, Phenoxyethanol, benzyl alcohol, sodium benzoate, potassium sorbate
One or more combination；It is preferred that two kinds of Phenoxyethanol, Nipasol etc. of composition.
Above-mentioned bioactive ingredients skin care item, preparation method the following steps are included:
(1) emollient, emulsifier are added in oily phase pot, are heated to 80 ~ 85 DEG C, stirring is melted to complete, obtains material A；
(2) moisturizer, thickener, water are added in water phase pot, are heated to 80 ~ 85 DEG C, stirred to being completely dissolved, obtain material B；
(3) material A and material B are pumped into emulsion pot, open homogeneous, 5 ~ 10min of homogeneous controls 70 ~ 80 DEG C of temperature, and heat preservation is stirred
Mix 10 ~ 20min；
(4) 40 ~ 45 DEG C are cooled to, preservative, arginine, essence, biological active component, water chestnut composition is added, stirs evenly,
It can discharge, bioactive ingredients skin care item are made.
Bioactive ingredients skin care item good penetrability provided by the invention easily absorbs, clearly not sticky using rear face, mends
Water, moistening effect are good, effectively calm down microgroove, reduce wrinkle, slowing down skin aging, and long-acting moisturizing, keep skin water profit smooth, have
Elasticity.
Specific embodiment
The invention discloses a kind of bioactive ingredients skin care item and its preparation process, those skilled in the art can be used for reference
The contents of the present invention are suitably modified realization of process parameters.In particular, it should be pointed out that all similar substitutions and modifications are to ability
It is it will be apparent that they are considered as being included in the scope of the present invention for field technique personnel.Application of the invention has been led to
Preferred embodiment is crossed to be described, related personnel obviously can not depart from the content of present invention, in spirit and scope to this paper institute
The methods and applications stated are modified or appropriate changes and combinations, carry out implementation and application the technology of the present invention.
Preparation example 1: the preparation of water chestnut extract -1
Water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, the deionized water of 12 times of its weight is added, is boiled 3 hours, collects and steams
The gas of hair condenses, obtains volatilization liquid；It will volatilize liquid be concentrated, be spray-dried, obtaining water chestnut extract -1.
Preparation example 2: the preparation of water chestnut extract -1
Water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, the deionized water of 20 times of its weight is added, is boiled 2 hours, collects and steams
The gas of hair condenses, obtains volatilization liquid；It will volatilize liquid be concentrated, be spray-dried, obtaining water chestnut extract -1.
Preparation example 3: the preparation of water chestnut extract -1
Water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, the deionized water of 16 times of its weight is added, is boiled 2.5 hours, is collected
The gas of evaporation condenses, obtains volatilization liquid；It will volatilize liquid be concentrated, be spray-dried, obtaining water chestnut extract -2.
Preparation example 4: the preparation of water chestnut extract -2
Water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, 75% ethanol solution of 15 times of its weight, extract return method 3 is added
Secondary, extracting solution concentration, spray drying are obtained water chestnut extract -2 by filtering, combined extract.
Preparation example 5: the preparation of water chestnut extract -2
Water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, 75% ethanol solution of 30 times of its weight, extract return method 2 is added
Secondary, extracting solution concentration, spray drying are obtained water chestnut extract -2 by filtering, combined extract.
Preparation example 6: the preparation of water chestnut extract -2
Water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, 75% ethanol solution of 24 times of its weight, extract return method 3 is added
Secondary, extracting solution concentration, spray drying are obtained water chestnut extract -2 by filtering, combined extract.
Embodiment 1: bioactive ingredients skin care item
Preparation method:
(1) emollient, emulsifier are added in oily phase pot, are heated to 80 ~ 85 DEG C, stirring is melted to complete, obtains material A；
(2) moisturizer, thickener, water are added in water phase pot, are heated to 80 ~ 85 DEG C, stirred to being completely dissolved, obtain material B；
(3) material A and material B are pumped into emulsion pot, open homogeneous, 5 ~ 10min of high speed homogenization controls 70 ~ 80 DEG C of temperature, protects
10 ~ 20min of temperature stirring；
(4) 40 ~ 45 DEG C are cooled to, preservative, arginine, essence, biological active component, water chestnut composition is added, stirs evenly,
Bioactive ingredients skin care item are made.
Embodiment 2: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 3: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 4: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 5: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 6: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 7: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 8: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 9: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 10: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Comparative example 1: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Comparative example 2: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Comparative example 3: bioactive ingredients skin care item
Preparation method:
(1) emollient, emulsifier are added in oily phase pot, are heated to 80 ~ 85 DEG C, stirring is melted to complete, obtains material A；
(2) moisturizer, thickener, water are added in water phase pot, are heated to 80 ~ 85 DEG C, stirred to being completely dissolved, obtain material B；
(3) material A and material B are pumped into emulsion pot, open homogeneous, 5 ~ 10min of high speed homogenization controls 70 ~ 80 DEG C of temperature guarantors
10 ~ 20min of temperature stirring；
(4) 40 ~ 45 DEG C are cooled to, preservative is added, arginine, essence, biological active component, stirs evenly, it is living that biology is made
Property ingredient skin care item.
Comparative example 4: bioactive ingredients skin care item
Preparation method: with embodiment 1.
Embodiment 11: moisture of skin and skin elasticity effect assessment
1, subjects: skin health, the volunteer of no skin disease allergies 150；It is divided into 15 groups, is divided into embodiment 1-10
Group, comparative example 1-4 group, control group, every group 10.
2, test equipment equipment: using the skin bullet of Courage+Khazaka company, Germany (German CK company) manufacture
Property CutometerMPA580 host is (including the Corneomet CM825 for detecting moisture content of skin, skin elasticity tester
MPA580 subsidiary flexibility test probe), the calibration of instrument is carried out before test, apparatus working is normal during test.
3, test zone: right hand inner forearm 3cm × 3cm；It is averaged after each test point duplicate measurements 3 times.
4, test method: 2-3 days before test, recipient site cannot use any product (skin care item, cosmetics and externally applied drug
Product etc.), moisture of skin, the skin elasticity value in tested region are measured, is averaged after each test point duplicate measurements 3 times, as 0
The measured value of its (before use).Volunteer presses (2.0 ± 0.1) mg sample/cm2Dosage, early daily, evening distinguishes in tested region
The skin care item of embodiment 1-10, comparative example 1-4 are smeared, control group smears embodiment 7 and removes bioactive ingredients and water chestnut extraction
The formulation product of object measures the moisture and elasticity number in tested region, as the measurement after 28 days after persistently smearing 28 days again
Value.
5, data processing: data are indicated with mean ± standard deviation (), are analyzed using SPSS11.5 statistical software.Between group
Compare using one way ANOVA, carries out Student-Newman-Keuls inspection
6, result
1, moisture content of skin is as a result, see the table below
Note: examining through One-Way ANOVA,﹟P<0.05、﹟ ﹟P < 0.01, compared with the control group
It is examined through One-Way ANOVA,●P<0.05、●●P < 0.01, compared with (0 day) before this group of use
It is examined through One-Way ANOVA,★P < 0.05, compared with Example 1；
It is examined through One-Way ANOVA,■P < 0.05, compared with Example 2
It is examined through One-Way ANOVA,**P < 0.01, compared with Example 7；
2, skin elasticity is as a result, see the table below
Note: examining through One-Way ANOVA,﹟P<0.05、﹟ ﹟P < 0.01, compared with the control group
It is examined through One-Way ANOVA,●P<0.05、●●P < 0.01, compared with (0 day) before this group of use
It is examined through One-Way ANOVA,★P < 0.05, compared with Example 1；
It is examined through One-Way ANOVA,■P < 0.05, compared with Example 2
It is examined through One-Way ANOVA,**P < 0.01, compared with Example 7；
(1) each group moisture content of skin and skin elasticity are without significant difference (P > 0.05) before testing.
(2) after the bioactive ingredients skin care item for smearing 1-10 of the embodiment of the present invention, moisture content of skin is significantly improved,
Skin elasticity is obviously improved, and compared with the control group, is had significant difference (P < 0.05 or P < 0.01)；With use preceding phase
Than having significant difference (P < 0.05 or P < 0.01).
(3) it after the bioactive ingredients skin care item for smearing embodiment of the present invention 5-6,9-10, significantly improves skin and contains
Water, skin elasticity are obviously improved, compared with the control group, the difference (P < 0.01) with highly significant；Before using
It compares, the difference (P < 0.01) with highly significant；Effect is better than embodiment 1-2 group and 3-4 group.
(4) after the bioactive ingredients skin care item for smearing 7-8 of the embodiment of the present invention, moisture content of skin is significantly improved,
Skin elasticity is obviously improved, compared with the control group, the difference (P < 0.01) with highly significant；Compared with before use,
Difference (P < 0.01) with highly significant；Compared with embodiment 1 and 2 groups of embodiment, have significant difference (P < 0.05), effect
Fruit is better than embodiment 5-6 group, embodiment 9-10 group.
(5) after smearing comparative example 1-2 bioactive ingredients skin care item of the present invention, moisture content of skin and skin elasticity are not obtained
Do not have significant difference (P > 0.05) compared with the control group to apparent improve with promotion；Compared with before use, do not have
Significant difference (P > 0.05)；Comparative example 1-2 is compared with 7 groups of embodiment, and only bioactive ingredients and proportion are different, with embodiment
7 groups are compared, the difference (P < 0.01) with highly significant, it can be seen that the type of biological active component is different from proportion, directly
Influence the moisturizing of bioactive ingredients skin care item of the present invention and the effect of elasticity, thus specifically biological active component, specific
Proportional region in, the skin care item moisturizing and skin elasticity effect being prepared are best.
(6) after smearing comparative example 3-4 bioactive ingredients skin care item of the present invention, moisture content of skin and skin elasticity are not obtained
Do not have significant difference (P > 0.05) compared with the control group to apparent improve with promotion；Compared with before use, do not have
Significant difference (P > 0.05)；Comparative example 3-4 is compared with 7 groups of embodiment, and only water chestnut extract is different, compared with 7 groups of embodiment,
Difference (P < 0.01) with highly significant, it can be seen that do not add water chestnut extract (comparative example 3) and water chestnut extract is different
Extracting method, directly affect the moisturizing of bioactive ingredients skin care item of the present invention and the effect of skin elasticity, therefore specific
The skin care item moisturizing and skin that water chestnut extract that extracting method obtains, additional amount are prepared in specific proportional region
Elastic effect is best.
Biological active component and specific proportion, particular extraction procedure in bioactive ingredients skin care item provided by the invention
The water chestnut extract of preparation has synergistic effect, in specific proportional region, can effectively improve moisture content of skin, promotes skin
Elasticity achievees the effect that moisturizing and skin elasticity.
Embodiment 12: crease-resistant efficacy assessments measurement
1, subjects: at 35~55 years old, there are volunteer 300 of skin health at the age, are divided into 15 groups, are divided into embodiment 1-
10 groups, comparative example 1-4 group, control group, every group 20.
2, test purpose: for the guarantor of the bioactive ingredients skin care item of testing example 1-10, comparative example 1-4 preparation
Wet and anti-wrinkle effect allows trier to test 30 days, and the formula of 7 bioactive ingredients of control group embodiment and water chestnut extract produces
Product.
3, test method: trier's bioactive ingredients skin care item are asked, and are given a mark according to result on trial.
4, standards of grading:
(1) be obviously improved: moistening effect is good, skin smooth is flexible, effectively calms down reduction wrinkle, and 2 points；
(2) improve to a certain degree: moistening effect preferably, skin smooth, elasticity, wrinkle calm down and reduce improvement, 1 point；
(3) without improvement: moistening effect is poor, skin smooth, elasticity, wrinkle calm down and reduce without improvement: 0 point.
It takes the marking result of 20 triers average, specifically see the table below:
Data analysis:
(1) using embodiment 1 ~ 10 prepare bioactive ingredients skin care item, tester evaluation average mark at 1.25 points or more,
Liking and approving by trier, trier indicate bioactive ingredients skin care item good penetrability of the present invention, easily absorb, make
Clearly not sticky with rear face, moisturizing, moistening effect are good, effectively calm down microgroove, reduce wrinkle, slowing down skin aging, and long-acting
Moisturizing keeps skin water profit smooth, flexible.
(2) using embodiment 3 ~ 10 prepare bioactive ingredients skin care item, tester evaluation average mark 1.6 points with
On, it has obtained a degree of improvement or has been obviously improved, achieved the effect that moisturizing and crease-resistant, effect is better than embodiment 1-2
Group.
(3) after the bioactive ingredients skin care item for using embodiment 7-8 to prepare, tester's evaluation is equally divided into 2 points,
Moistening effect is good, skin smooth is flexible, effectively calms down wrinkle, reduces wrinkle, has achieved the effect that moisturizing and crease-resistant, effect
Better than embodiment 1-2 group, embodiment 3-6 group, embodiment 9-10.
(4) using after comparative example 1-4 bioactive ingredients skin care item, the average mark of tester's evaluation is at 1.0 points hereinafter,
A degree of improvement is not obtained；Significant effect is worse than embodiment 7；It can be seen that difference (the comparative example 1- of bioactive ingredients
2), the water chestnut extract (comparative example 3-4) of different extraction process preparations, directly affects bioactive ingredients skin care item of the present invention
Effect, therefore the water chestnut extract that specific bioactive ingredients, specific proportion, special process are prepared, have collaboration
Effect, the skin care item moisturizing and anti-wrinkle effect being prepared are best.
Claims (9)
1. a kind of bioactive ingredients skin care item, which is characterized in that including following components in percentage by weight: biological active component
0.1-0.3%, water chestnut extract 4-8%, matrix components 20-24%, surplus are water；The biological active component, by following weight
The group of percentage is grouped as: wheat peptide 0.04-0.13%, oat peptide 0.02-0.07%, -1 0.02-0.05% of palmityl tripeptides,
- 10 0.01-0.05% of palmityl tetrapeptide.
2. bioactive ingredients skin care item as described in claim 1, which is characterized in that the biological active component, by with
The group of lower weight percent is grouped as: wheat peptide 0.05-0.10%, oat peptide 0.02-0.045%, -1 0.02- of palmityl tripeptides
0.038%, -10 0.01-0.036% of palmityl tetrapeptide.
3. bioactive ingredients skin care item as described in claim 1, which is characterized in that the biological active component, by with
The group of lower weight percent is grouped as: wheat peptide 0.084%, oat peptide 0.034%, palmityl tripeptides -1 0.026%, palmityl
Tetrapeptide -10 0.036%.
4. bioactive ingredients skin care item as described in claim 1, which is characterized in that the biological active component, by with
The group of lower weight percent is grouped as: wheat peptide 0.076%, oat peptide 0.042%, palmityl tripeptides -1 0.031%, palmityl
Tetrapeptide -10 0.021%.
5. bioactive ingredients skin care item as described in claim 1, which is characterized in that the water chestnut extract, preparation side
Method the following steps are included:
(1) preparation of water chestnut extract -1: water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, 12-20 times of its weight is added
Deionized water is boiled 2-3 hours, is collected the gas of evaporation, is condensed, obtains volatilization liquid；It will volatilize liquid be concentrated, be spray-dried, obtaining
To water chestnut extract -1；
(2) water chestnut fresh goods raw material is washed and chopped, smashs juicing to pieces, 15-30 times of its weight is added by the preparation of water chestnut extract 2
Extracting solution concentration, spray drying are obtained water chestnut and mentioned by 75% ethanol solution, extract return method 2-3 times, filtering, combined extract
Take object -2.
6. bioactive ingredients skin care item as claimed in claim 5, which is characterized in that the water chestnut extract is mentioned by water chestnut
2 component of object 1 and water chestnut extract is taken, wherein -1 1.2-2.7% of water chestnut extract, -2 3-7.3% of water chestnut extract.
7. bioactive ingredients skin care item as claimed in claim 5, which is characterized in that the water chestnut extract is mentioned by water chestnut
Take 2 component of object 1 and water chestnut extract, water chestnut extract -1 1.5%, water chestnut extract -2 4.2%.
8. bioactive ingredients skin care item as described in claim 1, the matrix components, by the group of following weight percent
It is grouped as: emulsifier 4-5%；Moisturizer 6 ~ 10%, emollient 7 ~ 9%, thickener 0.5-1%, preservative 0.1 ~ 0.2%, essence
0.1 ~ 0.3%, arginine 0.01 ~ 0.5%.
9. bioactive ingredients skin care item as claimed in claim 8, preparation method the following steps are included:
(1) emollient, emulsifier are added in oily phase pot, are heated to 80 ~ 85 DEG C, stirring is melted to complete, obtains material A；
(2) moisturizer, thickener, water are added in water phase pot, are heated to 80 ~ 85 DEG C, stirred to being completely dissolved, obtain material B；
(3) material A and material B are pumped into emulsion pot, open homogeneous, 5 ~ 10min of homogeneous, control 70 ~ 80 DEG C of heat preservations of temperature are stirred
Mix 10 ~ 20min；
(4) 40 ~ 45 DEG C are cooled to, preservative, arginine, essence, biological active component, water chestnut composition is added, stirs evenly,
It can discharge, bioactive ingredients skin care item are made.
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| CN114983855A (en) * | 2022-06-23 | 2022-09-02 | 北京化工大学 | Composite peptide with tyrosinase activity inhibition function and preparation method and application thereof |
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