CN109430650A - Prepare the formula and production technology of collagen, hyaluronic acid beverage and nourishing liquid - Google Patents

Prepare the formula and production technology of collagen, hyaluronic acid beverage and nourishing liquid Download PDF

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Publication number
CN109430650A
CN109430650A CN201811396726.6A CN201811396726A CN109430650A CN 109430650 A CN109430650 A CN 109430650A CN 201811396726 A CN201811396726 A CN 201811396726A CN 109430650 A CN109430650 A CN 109430650A
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collagen
beverage
tremella
extract
food materials
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王昱蓉
季静
王罡
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Tianjin City Days Tianfu Biological Technology Co Ltd
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Tianjin City Days Tianfu Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38Other non-alcoholic beverages
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/66Proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00Edible extracts or preparations of fungi; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses a kind of formulas and production technology that beverage and nourishing liquid are prepared by collagen, hyaluronic acid, renaturation method, hyaluronan extraction technology including removing amine etc.;Prepare the formula of beverage, the formula of nourishing liquid processed;Prepare the production technology of beverage liquid (object);Prepare the production technology etc. of nourishing liquid.It discloses to be formed using the collagen, the tremella polysaccharides extract that extract and beverage, the formula of nourishing liquid and production technology is prepared for main " food materials essence " material with food materials collagen, tremella extract (object).And its specific practical way: (1) prevent collagenous fibres connection solidification, increase iuntercellular mucopolysaccharide, anti-aging, wrinkle resistant, nti-freckle drink;(2) prevent the beverage and oral tonic liquor of cardiovascular and cerebrovascular disease and part malignant tumour;(3) drink of the aggregation of aluminium in vivo is reduced;(4) beverage and oral tonic liquor for preventing arthralgia, improving immunity;(5) it is damaged or the reparation person of allergy epidermis often uses drink.

Description

Prepare the formula and production technology of collagen, hyaluronic acid beverage and nourishing liquid
Technical field
The present invention relates to the formula, method and the production technologies that prepare collagen and hyaluronic acid beverage and nourishing liquid.
Background technique
Collagen (collagen) has 16 kinds or so, and common type is I type, II type, type III, IV type, V-type and XI type. Collagen is because having biocompatibility, degradability and biological function, therefore in food, medicine, organizational project, cosmetics etc. It is widely applied in field.I-type collagen is distributed mainly on the tissue such as skin, tendon, rich in there is alanine to be combined with sugar type Hydroxylysine, molecular length about 300nm, diameter about 1.5nm are made of, wherein there is two α (I) three peptide chains in rodlike Chain, α (II) chain act on body function most strong;II collagen type is generated by cartilage cell;IV collagen type category base Counterdie collagen is distributed mainly on basilar memebrane, and molecule is very tiny and is linearly distributed in organization internal, is connection epidermis With the main element of corium;Collagen type v egg is pericellular collagen, is distributed in around cell peripheral and type i collagen, It may work between basement membrane and connective tissue, largely exist in connective tissue.Collagen is human body natural's albumen, right The protein molecule of skin surface has biggish affinity, weaker antigenic, good biocompatibility and biodegrade Safety, degradable absorption, adhesion strength are good.Applied to beauty, food, drug, tonic.Early in 12nd century Bingen St.Hilde-gard is just described using the cartilage soup of calf as drug and is treated arthralgia.It is a kind of ideal drop blood Fat foods can reduce blood triglyceride and cholesterol.Collagen is the key that skeleton, locks calcium in cartilaginous tissue.Also It is the main component of sclera, it is also extremely important to the effect of eyes, if the synthesis of collagen reduces and degrades and increase in sclera Add and will lead to myopia.
Tremella (Tremella fuciformis), has promoting production of body fluid and nourishing the lung, tonifying Qi and blood, strong mesh kidney tonifying, and clear and rich benefit stomach is mended The effect of brain is refreshed oneself, and is promoted longevity, and heart tonifying strengthens body and anticancer.It can not only improve liver detoxification, moreover it is possible to it is anti-swollen to enhance body The immunocompetence of tumor, and tumor patient can be enhanced to the tolerance of radiotherapy, chemotherapy.Tremella is kind of the weight-reducing food containing dietary fiber Product, its dietary fiber can help gastrointestinal peristalsis, reduce fat absorption.
Nutritional ingredient contained by tremella is complex, and preliminary analysis shows tremella 6.7%-10% containing protein, carbon hydrate Object 65%-71.2%, fat 0.6%-12.8%, crude fibre 2.4%-2.75%, inorganic salts 4.0%-5.4%, moisture 15.2%-18.76% and a small amount of vitamine B group.Contain leucine, isoleucine, phenylalanine, ammonia in the protein of tremella Acid, serine, glutamic acid, pick propylhomoserin, proline, arginine, lysine, alanine, threonine, asparatate, tyrosine, 17 kinds of amino acid such as cystine, histidine, methionine, it is proline that wherein content is maximum.Main sulfur-bearing in inorganic salts, Iron, magnesium, calcium, potassium plasma.In every hectogram tremella, 643 milligrams of calcic, 30.4 milligrams of iron.Tremella extract is with polysaccharide Conjunction object is main active, and most representative is tremella acidity different polysaccharide (Acidic heteroglucan), and structure is Using α-mannosan as main chain, with β-(1,2) L- xylose, β-(1,2) glucuronic acid for side chain, there is typical second in molecule Acyl group structure.Other several polysaccharide bodies are neutral heteropolysaccharide.s, by xylose, mannose, galactolipin and glucuronic acid and D- pyrans Portugal Grape sugar composition.In addition, also containing the glycogen such as trehalose, pentosan, mannitol, nutritive value rich in vitamin D in tremella It is very high, it is a kind of advanced cosmetic material.
The present invention uses scientific and effective method, forms a kind of collagen, hyaluronic acid beverage and nourishing liquid of preparing Formula and production technology.
Summary of the invention
1, it is an object of the invention to the extracts for doing main material with food materials collagen and tremella to prepare beverage and taste The formula and production technology of fluid infusion.
2, second object of the present invention is that the renaturation method extraction collagen of amine etc. is provided to reach in 1 and requiring Technique.
3, third object of the present invention is that it is more to provide one Hot water extraction of grain wine extraction tremella to reach in 1 and requiring The technique and technology of sugar.
4, fourth object of the present invention is provided based on food materials collagen, tremella extract to reach in 1 and requiring Material is wanted to do a kind of " food materials essence " formula for preparing beverage by collagen, tremella extract (object).
5, the 5th purpose of the invention is provided based on food materials collagen, tremella extract to reach in 1 and requiring Material is wanted to do " food materials essence " one kind by collagen, the formula of tremella extract (object) nourishing liquid processed.
6, the 6th purpose of the invention is provided based on food materials collagen, tremella extract to reach in 1 and requiring Material is wanted to do a kind of production technology for preparing beverage liquid (object) by collagen, tremella extract.
7, the 7th purpose of the invention is provided based on food materials collagen, tremella extract to reach in 1 and requiring Material is wanted to do a kind of " food materials essence " production technology for preparing nourishing liquid by collagen, tremella extract (object).
Technical scheme is as follows:
1, the technique for going the renaturation method of amine etc. to extract collagen:
In order to guarantee the edibility of collagen, the extraction method that chemical molecular denaturation is aided with based on physical method is to prepare Raw material is passed through after removing the pre-treatments such as foreign protein, is directly extracted with thermal denaturation under certain condition by the guarantee of green food Pretreated collagen or collagen hydrolysate.It chooses carefully out first Animal Skin, bone, hyaline cartilage and fish-skin etc. The material of collagen is prepared, equal vinegar does not impregnate 0-2 hours with 10%-100% respectively, removes part ion and amine, during which removes The sundries such as hair, rouge.Then, the water of immersion is outwelled, tap water, distilled water or mineral water is added in weight ratio water 1: 0.5-50 Etc. it is any have or the clear water of non-treated mistake in, boil the small time variation of 0.5-10 under high pressure or non-high-pressure situations, heat preservation until Room temperature, 4000g centrifugation are gone to combine glycolipid, be boiled again.The physical methods such as high pressure auxiliary can also be used, high pressure auxiliary and hot water are taken out Extraction of the needle to gelatin, and low temperature extracting is directed to the extraction of collagen, but its basic principle is all the characteristic according to collagen Change the external environment where protein, collagen is separated, during actual extracting, between Different Extraction Method It often be combined with each other, gives HIGH PRESSURE TREATMENT for a period of time to raw material using ultra high pressure treatment system, make its institutional framework and collagen The triple helix structure of albumen is relaxed, is denaturalized, and is convenient for separation and Extraction, and finally heat preservation nature is cool, goes to combine glycolipid, renaturation is extremely 30-70 degree, is filtered for multiple times.
Form the mixing stoste A liquid containing collagen Types I, II type, type III, IV type, V-type and XI type.
, grain wine-Hot water extraction the technique of extracting tremella polysaccharides:
It is first impregnated tremella 30 seconds with high spirit, later, with yellow tremella tissue is removed, is filtered after elution, the ratio of tremella and water Example is 1: 0.5-500.It after tremella is rinsed with water, is soaked in water, adjusts pH value to a certain range.In view of consumption tremella Polysaccharide, the present invention obtain this plant-derived hyaluronic acid-like substance with physical method, are heated to 90-100 degree, keep macromolecule Reach 100-130 ten thousand, the isothermal reaction time 0.3-10 hours;Coolant water temperature is filtered with 50-300 mesh to pumping later to 20-80 degree Filter 2-3 times, until extract clear.Or 4500rpm is centrifugated 10min, finally takes supernatant stand-by, this method mentions Rate is taken to be up to 95%, product purity is high.Can also be directed to different taste, not filter, tremella is blended, formed little particle beverage or Solution additive is nourished, embodies the effect of surmounting hyaluronic acid more.It forms stoste and is referred to as B liquid, B liquid can be diluted with several levels.
, prepare by collagen, tremella extract the formula of beverage.
Collagen has degradability, stability and absorbability.
Collagen can be by specific proteasome degradation, i.e. biological degradability.Because collagen has the helical structure of close and firm, institute Its side chain can only be cut off with most protease, the only specific protease such as clostridiopetidase A, elastoser is in specific item Could degrade collagen under part, be broken collagen peptide bond.Once be broken, helical structure is destroyed and thorough immediately for the peptide bond of collagen Bottom is hydrolyzed to micromolecule polypeptide or amino acid, and small-molecule substance can enter blood circulation system, by body re-using or generation Thank to discharge.Collagen is human body nature albumen, has biggish affinity, weaker anti-to the protein molecule of skin surface Originality, good biocompatibility and biodegradable safety, degradable absorption, adhesion strength are good.It can be used for beauty, food.
Tremella is sweet in flavor, light, mild-natured, nontoxic, existing nourishing Yin and moistening lung, QI invigorating gut purge effect, and can enhance human immunity, Enhance tumor patient to the tolerance of Radiotherapy chemotherapy.Tremella has the function of enriching yin, is rich in natural plant colloid, additional its The good moisturizing food that can be taken for a long time.Skin elasticity can be enhanced, plentiful subcutaneous tissue, reduce smooth out wrinkles, make skin Seem delicate smooth, and is effectively prevented toxic dust in the evaporation and virus and air of moisture and is invaded from skin pore and made The harm of pairs of human body, the tremella polysaccharides that molecular weight reaches 100-130 ten thousand are a kind of food materials source property hyaluronic acid-like substances.
Collagen, tremella extract and mixture prepare the formula (100 milliliters) of beverage are as follows:
Extract A liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
Extract B liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
(single plus a kind of can also)
Mineral water, distilled water or clean water: 30-98ml (is adjusted) according to taste and suitable sensitivity
Sugar or sweetener: carbohydrate, honey or xylitol (according to whether being diabetes or selection)
Food additives: citric acid, sodium citrate, sodium benzoate and edible essence within the scope of national standard.
Any other active principle, such as a series of substances of fructus lycii, jujube can also be added.
, prepare by collagen, tremella extract the meaning and formula of nourishing liquid.
A in above-mentioned 1,2 is taken, B liquid, preparation prepares nourishing liquid by collagen, tremella extract, in addition to benefit in above-mentioned 3, St.Hilde-gard early in 12nd century Bingen is just described using the cartilage soup of calf as drug and is treated arthritis Bitterly, in the quite a long time, some products containing collagen are by it is believed that be very helpful to joint.It or one The ideal blood fat reducing food of kind, can reduce blood triglyceride and cholesterol.Collagen can assist to exclude intracorporal aluminium, subtract The few aggregation of aluminium in vivo reduces harm of the aluminum to human body, and promotes the growth of nail and hair to a certain extent.Collagen egg White or sclera main component, it is also extremely important to the effect of eyes, if the synthesis of collagen is reduced and is dropped in sclera Solution, which increases, will lead to myopia.
Tremella can enhance tumor patient to the tolerance of radiotherapy, chemotherapy, and because being rich in selenium and other trace elements, machine is can be enhanced in it The antitumor immunity of body.Tremella polysaccharides have the ability of inhibitory activity oxygen activity, play the role of oxidation resistant.It is recommended that adding silver Ear, experimental data shows to isolate horn cell from the skin of rat and fibrocyte is cultivated, and is added in the medium Tremella polysaccharides.After culture 24 hours, the activity of SOD is measured in 37 DEG C, 5% C02.1) horn cell (Keratinocyte) 0.1% or more tremella polysaccharides are added, the activity of SOD improves.2) fibrocyte (Fibroblast) is added 0.05% or more Tremella polysaccharides, the activity of SOD improves.These show that tremella polysaccharides are oxidation resistant with the experiment in vitro that Skin Cell is done Effect.
100ml " food materials essence " is prepared the formula of nourishing liquid by collagen, tremella extract:
Extract A liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
Extract B liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
(single plus a kind of can also)
Mineral water, distilled water or clean water: 30-90ml (is adjusted) according to taste and suitable sensitivity
Sugar or sweetener: carbohydrate, honey or xylitol (according to whether being diabetes or selection)
Food additives: sodium benzoate within the scope of national standard and sorbic acid and sodium sorbate, edible essence.
Any other active principle, such as a series of substances of fructus lycii, jujube can also be added.
, a kind of production technology that beverage is prepared by collagen, tremella " food materials essence " extract:
This technique strict implement sterilization product specification.
Production technology are as follows:
B liquid is extracted, 1-50 parts, temperature is 0-100 degree, and 0-10 parts of A liquid are added, and temperature is unlimited, and food additives: national standard model are added Enclose interior citric acid, sodium citrate, sodium benzoate and edible essence.Any other active principle, such as fructus lycii, jujube can also be added Etc. a series of substances or extract.80-99.9 parts of addition, 4-100 degree distilled water or mineral water or pure water, are sufficiently mixed, go out Bacterium is distributed into bottle.
This production technology can be required according to different production lines, be improved, still, it is desirable that and it is final sterile, or stringent symbol Close country, international standard.
, a kind of production technology that nourishing liquid, oral solution are prepared by collagen, tremella " food materials essence " extract:
This technique strict implement sterilization product specification.
Production technology are as follows:
B liquid is extracted, 1-60 parts, temperature is 0-100 degree, and 0-20 parts of A liquid are added, and temperature is unlimited, and food additives: national standard model are added Enclose interior citric acid, sodium citrate, sodium benzoate and edible essence.Any other active principle, such as fructus lycii, jujube can also be added Etc. a series of substances or extract.70-99.0 parts of addition, 4-100 degree distilled water or mineral water or pure water, are sufficiently mixed, go out Bacterium is distributed into bottle.
This production technology can be required according to different production lines, be improved, still, it is desirable that and it is final sterile, or stringent symbol Close country, international standard.
Embodiment 1
Prevent collagenous fibres connection solidification, increase iuntercellular mucopolysaccharide, anti-aging, wrinkle resistant, nti-freckle drink:
With advancing age, fibroblastic synthesis capability decline, if lacking collagen in skin, collagenous fibres will Connection solidification occurs, reduces iuntercellular mucopolysaccharide, skin will lose soft, elasticity and gloss, and aging occurs, and collagen is more It is that Animal Skin is extracted, containing substances such as hyaluronic acid, chondroitin sulfates in skin, they contain a large amount of polar groups, are to protect The wet factor, and play the role of prevent skin in tyrosine be converted into melanin, while prevent the fibrous fracture of corium, fat withers Contracting, sweat gland and smegma are reduced, and skin is made a series of aging phenomena such as color spot, wrinkle occur.Therefore collagen has pure day The effects of right moisturizing, whitening, wrinkle resistant, nti-freckle, collagen is similar to the structure of human skin collagen, for non-soluble fiber shape Containing glycoprotein, it is rich in a large amount of amino acid and hydrophilic group in molecule, there is certain surface-active and good compatibility, simultaneously Due to containing a large amount of hydroxyl in its molecule, it has fairly good nutrition and moisture-keeping function.Drinking and smearing can expand It is scattered to the deep layer of tissue, human body, skin, the integrality of cuticula moisture and fibre structure is kept, promotes the new of skin histology Old metabolism generates good moist moisturizing to skin, effect wrinkles eliminating vanishing acts on.Early in the early 1970s, the U.S. just takes the lead in pushing away Injection bovine collagen out for nti-freckle wrinkle and repairs scar.
Tremella polysaccharides are considered a kind of plant-derived hyaluronic acid-like substance, and molecular weight reaches 100-130 ten thousand, is So far, in cosmetic material circle unique molecular weight can reach 1,000,000 or more plant origin moisturizer.With it is saturating When bright matter acid is compared, the effect of many surmounts hyaluronic acid has been embodied.Tremella polysaccharides have keratoderma good Good nourishing effect can be enhanced skin elasticity, plentiful subcutaneous tissue, reduce smooth out wrinkles, and skin is made to seem delicate smooth.It is real It tests and shows that the film of tremella polysaccharides is more more flexible than the film of Sodium Hyaluronate, there are crease resistant functions.Tremella, which has, to be surmounted in hyalomitome The moisture-keeping function of acid mainly forms hydrogen bond by numerous terminal hydroxyl and water molecules, to combine close to 500 times Hydrone.
A in above-mentioned 1,2 is taken, B liquid, preparation " food materials essence " is a kind of to be prepared by collagen, tremella extract and mixture The formula of beverage.
(for 100 milliliters, can expand and reduce) are as follows:
Extract A liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
Extract B liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
(single plus a kind of can also)
Mineral water, distilled water or clean water: 30-98ml (is adjusted) according to taste and suitable sensitivity
Sugar or sweetener: carbohydrate, honey or xylitol (according to whether being diabetes or selection)
Food additives: citric acid, sodium citrate, sodium benzoate and edible essence within the scope of 0- national standard.
Any other active principle, such as a series of substances of fructus lycii, jujube can also be added.
The beverage and nourishing liquid prepared by collagen, tremella is formed, it can be in the air pollutions such as smoker and haze People has effect of clearing away lung-heat.
Embodiment 2
The beverage and oral tonic liquor for preventing cardiovascular and cerebrovascular disease and part malignant tumour:
Collagen is a kind of ideal blood fat reducing food, can reduce blood triglyceride and cholesterol, and can be increased in vivo The essential trace element of certain shortages is allowed to maintain within an opposite normal range (NR).II Collagen Type VI is in articular cartilage Major protein, thus be potential autoantigen.It can induce T cell after oral and generate immune tolerance, so that T cell be inhibited to mediate Autoimmune disease.
Tremella has the effect of heart tonifying strengthens body and anticancer.It can not only improve liver detoxification, moreover it is possible to it is anti-swollen to enhance body The immunocompetence of tumor, and tumor patient can be enhanced to the tolerance of radiotherapy, chemotherapy.Tremella is kind of the weight-reducing food containing dietary fiber Product, its dietary fiber can help gastrointestinal peristalsis, reduce fat absorption.
The beverage of 100ml (for 100 milliliters, can expand and reduce) prevention cardiovascular and cerebrovascular disease and part malignant tumour And oral tonic liquor:
Extract A liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
Extract B liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
(single plus a kind of can also)
Mineral water, distilled water or clean water: 30-90ml (is adjusted) according to taste and suitable sensitivity
Sugar or sweetener: carbohydrate, honey or xylitol (according to whether being diabetes or selection)
Food additives: sodium benzoate within the scope of 0- national standard and sorbic acid and sodium sorbate, edible essence.
Any other active principle, such as a series of substances of fructus lycii, jujube can also be added.
The beverage and nourishing liquid prepared by collagen, tremella etc. " food materials essence " is formed, cardiovascular and cerebrovascular disease can be prevented With the beverage and oral tonic liquor of part malignant tumour.
Embodiment 3
Food materials essence --- reduce the beverage and oral tonic liquor of the aggregation of aluminium in vivo:
Some researches show that collagen can assist to exclude intracorporal aluminium, reduce the aggregation of aluminium in vivo, reduce aluminum to human body Harm.
Tremella is promoted longevity with promoting production of body fluid and nourishing the lung, tonifying Qi and blood, strong mesh kidney tonifying, clear and rich benefit stomach, brain refreshing, and heart tonifying is strong The effect of body and anticancer.
Collagen, tremella extract and mixture prepare the formula (100 milliliters) of beverage are as follows:
Extract A liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
Extract B liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
(single plus a kind of can also)
Mineral water, distilled water or clean water: 30-98ml (is adjusted) according to taste and suitable sensitivity
Sugar or sweetener: xylitol
Food additives: citric acid, sodium citrate, sodium benzoate and edible essence within the scope of national standard.
Any other active principle, such as a series of substances of fructus lycii, jujube can also be added.
B liquid is extracted, 1-60 parts, temperature is 0-100 degree, and 0-20 parts of A liquid are added, and temperature is unlimited, and food additives: 0- are added Citric acid, sodium citrate, sodium benzoate and edible essence within the scope of national standard.Any other active principle, such as Chinese holly can also be added A series of substances of Qi, jujube etc. or extract.70-99.0 parts of addition, 4-100 degree distilled water or mineral water or pure water, sufficiently Mixing, that is, form food materials essence --- and moisturizing is wrinkle resistant, pre- anti-aging beverage and oral tonic liquor.
Embodiment 4
The beverage and oral tonic liquor for preventing arthralgia, improving immunity:
Collagen also can be used for preventing the beverage and oral tonic liquor of arthralgia, early in 12nd century Bingen St.Hilde-gard is just described using the cartilage soup of calf as drug and is treated arthralgia, at quite long one section Between in, some products containing collagen are by it is believed that be very helpful to joint.Collagen is skeleton, especially soft Important composition ingredient in bone tissue.As soon as collagen is just as the net full of duck eye in bone, it can firmly be kept here What is be lost is calcareous.It is full of the net of duck eye without this, even supplements excessive calcium, can also be lost in vain.
Tremella is promoted longevity with promoting production of body fluid and nourishing the lung, tonifying Qi and blood, strong mesh kidney tonifying, clear and rich benefit stomach, brain refreshing, and heart tonifying is strong The effect of body and anticancer.It can not only improve liver detoxification, moreover it is possible to enhance the antitumor immunocompetence of body, and can enhance Tolerance of the tumor patient to radiotherapy, chemotherapy.Tremella is kind of the diet food containing dietary fiber, its dietary fiber can help stomach and intestine It wriggles, reduces fat absorption.Both food materials are suitable for all ages, form few person in middle and old age and often use beverage:
It can increase and decrease by a certain percentage, or add other substances:
B liquid is extracted, 1-50 parts, temperature is 0-100 degree, and 0-10 parts of A liquid are added, and temperature is unlimited, and food additives: 0- national standard are added Citric acid, sodium citrate, sodium benzoate and edible essence in range.Any other active principle can also be added, such as fructus lycii, jujube Etc. a series of substances or extract.80-99.9 parts of addition, 4-100 degree distilled water or mineral water or pure water, are sufficiently mixed, Sterilizing, is distributed into bottle.
Embodiment 5
Impaired or allergy epidermis reparation person often uses beverage and nourishing liquid:
Collagen is extracted by Animal Skin, also contains the proteoglycans such as hyaluronic acid, chondroitin sulfate in skin in addition to collagen, They contain a large amount of polar groups, are moisturizing factors, and play the role of that the tyrosine in skin is prevented to be converted into melanin, therefore glue Former albumen has the effects of pure natural moisturizing, whitening, wrinkle resistant, nti-freckle, can be widely applied in cosmetic products.The chemistry of collagen Composition, structure impart it be beauty basis.Collagen is similar to the structure of human skin collagen, is non-soluble fiber Shape contains glycoprotein, is rich in a large amount of amino acid and hydrophilic group in molecule, has certain surface-active and good compatibility, together When due in its molecule contain a large amount of hydroxyl, it has fairly good moisture-keeping function.In relative humidity 70%, still may be used Keep the moisture of its own weight 45%.Test proves: the pure solution of 0.01% collagen can form water conservation layer well, Supply whole moisture required for skin.
With advancing age, fibroblastic synthesis capability decline, if lacking collagen in skin, collagenous fibres will Occur to join solidification, reduce iuntercellular mucopolysaccharide, skin will lose soft, elasticity and gloss, generation aging, while corium Fibrous fracture, lipoatrophia, sweat gland and smegma are reduced, and skin is made a series of aging phenomena such as color spot, wrinkle occur.It will When it is used in cosmetics as active material, the latter can be spread to the deep layer of skin, in the tyrosine and skin contained Tyrosine competition to inhibit the generation of melanin, make the collagen egg in skin and in conjunction with the catalytic center of tyrosinase White increased activity keeps the integrality of cuticula moisture and fibre structure, promotes the metabolism of skin histology, produces to skin Raw good moist moisturizing, effect wrinkles eliminating vanishing effect.Early in the early 1970s, the U.S. just takes the lead in releasing injection bovine collagen, For nti-freckle wrinkle and repair scar.
But in cosmetics, it is used as trophism skin type raw material merely and usually requires that molecular weight in 2KD hereinafter, hydrolyzing glue to allow Proper energy infiltrates through in skin.And hair care category cosmetics except require hydrolytic collagen have moisture retention in addition to, should also have it is certain at Film property, therefore, the molecular weight requirement of hydrolytic collagen can be higher.
Tremella polysaccharides are considered a kind of plant-derived hyaluronic acid-like substance, and it is so far that molecular weight, which reaches 100-130 ten thousand, Until, unique molecular weight can reach the moisturizer of 1,000,000 or more plant origin in cosmetic material circle.With hyalomitome When acid is compared, the effect of many surmounts hyaluronic acid has been embodied.Tremella has (1) moisture retention: its moisture-keeping function Principle is to form hydrogen bond by numerous terminal hydroxyl and water molecules, to form one in space in conjunction with a large amount of water A spongiform structure of molecule.Such moisturizing principle has also been bonded popular one of current state-of-the art water imbibition moisturizer and has become Gesture.(2) anti-oxidant:, tremella polysaccharides are other than with fabulous water retention, additionally it is possible to which the activity of inhibitory activity oxygen plays Oxidation resistant effect.(3) film forming: the aqueous solution of tremella polysaccharides and Sodium Hyaluronate being placed in evaporating dish and is dried, silver The film shrinking percentage of fungus polysaccharides is only 10%, and the film shrinking percentage of Sodium Hyaluronate has nearly reached half, it was demonstrated that tremella polysaccharides film It is not shunk with the variation of humidity, so not having tight feeling.Tremella polysaccharides have good affinity to skin, make skin Skin becomes to moisten, is smooth.
100ml " food materials essence " is impaired or the reparation person of allergy epidermis often uses beverage and nourishing liquid the preparation method is as follows:
Extract A liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
Extract B liquid: 0-40ml (is adjusted) according to taste and suitable sensitivity
(single plus a kind of can also)
Mineral water, distilled water or clean water: 30-90ml (is adjusted) according to taste and suitable sensitivity
Sugar or sweetener: carbohydrate, honey or xylitol (according to whether being diabetes or selection)
Food additives: sodium benzoate within the scope of national standard and sorbic acid and sodium sorbate, edible essence.
Any other active principle, such as a series of substances of fructus lycii, jujube can also be added.

Claims (7)

1. claim purpose of the invention is that the extract (object) of main material is made in protection of food materials collagen and tremella Prepare the formula and production technology of beverage and nourishing liquid.
2. second object of the present invention is to protect the renaturation method for removing amine etc. of offer to extract collagen to reach in 1 and requiring Technique.
3. third object of the present invention is to protect the grain wine of offer-Hot water extraction extraction tremella more to reach in 1 and requiring The technique and technology of sugar.
4. fourth object of the present invention is to reach in 1 and requiring, protect offer is with food materials collagen, tremella extract Main material does a kind of " food materials essence " formula that beverage is prepared by collagen, tremella extract (object).
5. the 5th purpose of the invention is to reach in 1 and requiring, protect offer is with food materials collagen, tremella extract Main material does " food materials essence " one kind by collagen, the formula of tremella extract (object) nourishing liquid processed.
6. the 6th purpose of the invention is to reach in 1 and requiring, protect offer is with food materials collagen, tremella extract Main material does a kind of production technology that beverage liquid (object) is prepared by collagen, tremella extract.
7. the 7th purpose of the invention is to reach in 1 and requiring, protection is provided is to food materials collagen, tremella extract Main material does a kind of " food materials essence " production technology that nourishing liquid is prepared by collagen, tremella extract (object).
And its specific embodiment: (1) preventing collagenous fibres connection solidification, increase iuntercellular mucopolysaccharide, anti-aging, wrinkle resistant, dispels Spot drink;(2) prevent the beverage and oral tonic liquor of cardiovascular and cerebrovascular disease and part malignant tumour;(3) aluminium is reduced in vivo The beverage and oral tonic liquor of aggregation;(4) beverage and oral tonic liquor for preventing arthralgia, improving immunity;(5) be damaged or The reparation person of person's allergy epidermis often uses beverage and nourishing liquid.
CN201811396726.6A 2018-11-22 2018-11-22 Prepare the formula and production technology of collagen, hyaluronic acid beverage and nourishing liquid Pending CN109430650A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020245809A3 (en) * 2019-06-07 2021-01-14 Vivatis Pharma Gmbh Identification and selection of a plant starting material of a plant chondroitin sulfate and hyaluronic acid, and transformation of such plant starting material to obtain ingredients for use in foods, supplements, medical devices or drugs
CN112704235A (en) * 2020-12-28 2021-04-27 陕西医赛尔生物科技有限公司 Silver-medlar active collagen oral liquid and preparation method thereof
CN112998168A (en) * 2021-04-23 2021-06-22 绿优品(福建)健康科技研发中心有限公司 Hyaluronic acid composite polypeptide beverage and preparation method thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102813115A (en) * 2012-09-10 2012-12-12 北京姿美堂生物技术有限公司 Compound active cosmetic collagen powder
CN103549601A (en) * 2013-11-18 2014-02-05 北京姿美堂生物技术有限公司 Women care and nourishing beverage
CN103637186A (en) * 2013-11-21 2014-03-19 宁夏多维药业有限公司 Oral liquid containing fish collagen protein and plant extract, and preparation method thereof
CN107522782A (en) * 2017-09-26 2017-12-29 天津市天大天福生物技术有限公司 A kind of preparation method and applications of gradient collagen and collagen polypeptide molecule
CN107536043A (en) * 2017-09-28 2018-01-05 镇江中广告制品有限公司 A kind of fish glue oral liquid and preparation method thereof
CN107828841A (en) * 2017-11-06 2018-03-23 天津市天大天福生物技术有限公司 The extracting method of a kind of collagen and collagen polypeptide and the application in cosmetics
CN108354096A (en) * 2018-02-06 2018-08-03 北京姿美堂生物技术有限公司 A kind of crease-resistant moisturizing, the collagen compound beverage for improving skin elasticity

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102813115A (en) * 2012-09-10 2012-12-12 北京姿美堂生物技术有限公司 Compound active cosmetic collagen powder
CN103549601A (en) * 2013-11-18 2014-02-05 北京姿美堂生物技术有限公司 Women care and nourishing beverage
CN103637186A (en) * 2013-11-21 2014-03-19 宁夏多维药业有限公司 Oral liquid containing fish collagen protein and plant extract, and preparation method thereof
CN107522782A (en) * 2017-09-26 2017-12-29 天津市天大天福生物技术有限公司 A kind of preparation method and applications of gradient collagen and collagen polypeptide molecule
CN107536043A (en) * 2017-09-28 2018-01-05 镇江中广告制品有限公司 A kind of fish glue oral liquid and preparation method thereof
CN107828841A (en) * 2017-11-06 2018-03-23 天津市天大天福生物技术有限公司 The extracting method of a kind of collagen and collagen polypeptide and the application in cosmetics
CN108354096A (en) * 2018-02-06 2018-08-03 北京姿美堂生物技术有限公司 A kind of crease-resistant moisturizing, the collagen compound beverage for improving skin elasticity

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020245809A3 (en) * 2019-06-07 2021-01-14 Vivatis Pharma Gmbh Identification and selection of a plant starting material of a plant chondroitin sulfate and hyaluronic acid, and transformation of such plant starting material to obtain ingredients for use in foods, supplements, medical devices or drugs
CN114174349A (en) * 2019-06-07 2022-03-11 维瓦蒂斯制药公司 Identification and selection of plant starting materials of the plant chondroitin sulphate and hyaluronic acid, and transformation of the plant starting materials to obtain ingredients for food, supplements, medical devices or drugs
CN112704235A (en) * 2020-12-28 2021-04-27 陕西医赛尔生物科技有限公司 Silver-medlar active collagen oral liquid and preparation method thereof
CN112998168A (en) * 2021-04-23 2021-06-22 绿优品(福建)健康科技研发中心有限公司 Hyaluronic acid composite polypeptide beverage and preparation method thereof
CN112998168B (en) * 2021-04-23 2023-09-15 绿优品(福建)健康科技研发中心有限公司 Hyaluronic acid composite polypeptide beverage and preparation method thereof

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Application publication date: 20190308