CN109364209A - A kind of cataplasm thermal sensation drug paste and preparation method thereof - Google Patents

A kind of cataplasm thermal sensation drug paste and preparation method thereof Download PDF

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CN109364209A
CN109364209A CN201811140008.2A CN201811140008A CN109364209A CN 109364209 A CN109364209 A CN 109364209A CN 201811140008 A CN201811140008 A CN 201811140008A CN 109364209 A CN109364209 A CN 109364209A
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parts
drug
cataplasm
thermal sensation
paste
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程艳青
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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    • A61K36/906Zingiberaceae (Ginger family)
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
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    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0625Warming the body, e.g. hyperthermia treatment
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659Radiation therapy using light characterised by the wavelength of light used infrared
    • A61N2005/066Radiation therapy using light characterised by the wavelength of light used infrared far infrared

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Abstract

The invention discloses a kind of cataplasm thermal sensation drug pastes, the drug paste includes primary backing, and paste layer is arranged on primary backing, drug ingedient is arranged on paste layer, it in mass ratio include consisting of: 1 ~ 3 part of raw rhubarb, 6 ~ 10 parts of Cortex Magnoliae Officinalis, 6 ~ 10 parts of fructus piperis longi, 5 ~ 8 parts of evodia rutaecarpa, 3 ~ 6 parts of radix aucklandiae, 3 ~ 5 parts of Schisandra sphnanthera, 3 ~ 6 parts of Radix picrorrhizae, 6 ~ 10 parts of the tuber of pinellia, 3 ~ 6 parts of the dried immature fruit of citron orange, 6 ~ 10 parts of galanga, 6 ~ 10 parts of myrobalan, 3 ~ 6 parts of nutmeg, 1 ~ 3 part of kuh-seng, 100 ~ 150 parts of deionized water, unique formula of the invention, preparation method is reasonable;Suitable for eliminating dampness to stop diarrhea and fortune spleen, for infantile diarrhea caused by wet tired spleen soil, symptoms include: diarrhea, loose watery stool or water sample, abdominal distension, abdominal pain, receive it is poor, vomit or see that greasy fever, pale tongue with white fur and rotaviral enteritis and noninfectious diarrhea are shown in above-mentioned patient.

Description

A kind of cataplasm thermal sensation drug paste and preparation method thereof
Technical field:
The present invention relates to field of medicaments, in particular to a kind of cataplasm thermal sensation drug paste and preparation method thereof.
Background technique:
Baby diarrhea is China's infant's common disease, seriously affects the health and growth and development of children, particularly infant, in the past It is mainly treated with western medicine antibiotics, but Western medicine toxic side effect is big, and current Traditional Chinese medicine antidiarrheal is only for weakness of the spleen and the stomach caused Digestive tract function disorder is treated: extensively plain antidiarrhea oral liquid just makes up the deficiency of front antidiarrheal agent to children, has no toxic side effect, The effects of capable of inhibiting and kill Escherichia coli and rotavirus, having spleen benefiting and stimulating the appetite concurrently, bring down a fever, help digestion and improve immunity of organisms. Meanwhile this product has adjustment effect to dehydration, electrolyte imbalance caused by diarrhea rich in body trace elements such as potassium, sodium, magnesium, zinc.
Raw rhubarb purges heat logical intestines, dispelling stasis of blood and stimulating the menstrual flow, removing pattogenic heat from the blood and toxic material from the body.For blood stasis closed, traumatic injury, jaundice with damp-heat pathogen, blood-head Hematemesis, real heat constipation, stagnate abdominal pain, and abdominalgia with intestinal abscess, dysentery is not well, hot eyes, pharynx swelling, and carbuncle swells furunculosis controls scald outside;On disappear Change gastrointestinal hemorrhage.
Cortex Magnoliae Officinalis is the major functions: stagnation of QI due to dyspepsia;Abdominal distention constipation;Damp retention in middle-jiao, abdominal swelling and diarrhea;Phlegm stops up the circulation of vital energy in the wrong direction;Chest full of cough.
Fructus piperis longi is the major functions: for coldness and pain in the epigastrium, vomiting, diarrhea, vomit acid regurgitation, increased borborygmus and diarrhea, cold dysentery.
Evodia rutaecarpa: major function eliminating cold to stop pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For jueyin headache, cold hernia stomachache, cold-dampness Tinea pedis, dysmenorrhea, abdominal distention vomit acid regurgitation, and Diarrhoea controls aphtha outside;Hypertension.
Radix aucklandiae, [curing mainly]: born of the same parents coerce turgor foot;Abdominal distention;Vomiting and having loose bowel;Weight after dysentery.
Schisandra sphnanthera: fruit controls indigestion, enteritis, diarrhea, vomits hiccup, gas pain, faintness dizziness,
Radix picrorrhizae is the major functions: deficiency of Yin hectic fever due to yin;Hectic fever night sweat;Infant malnutrition;Damp-heat dysentery;Jaundice;It spits blood;Bleeding from five sense organs or subcutaneous tissue;Red eye, swell pain;Carbuncle Swollen sore;Hemorrhoid pyogenic infections
The tuber of pinellia [major function] is eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Wet phlegm and cold drink is controlled, is vomitted, gastric disorder causing nausea, cough and phlegm, chest Diaphragm turgor, phlegm and headache, dizziness and sleepless.Outer subduing inflammation.
Dried immature fruit of citron orange effect internal stagnation;Feeling of fullness distending pain;Constipation;Weight after rush down dysentery;Accumulation of pathogens in chest;Gastroptosis;Rectal prolapse.
The effect of myrobalan has relieving diarrhea with astringents, astringes the lung to stop cough, fall fire relieving sore-throat.It is usually used in protracted dysentery and diarrhea, hematochezia rectal prolapse, the deficiency syndrome of the lung It breathes with cough, coughs long more than, pharyngalgia hoarse voice.
Galanga can pungent scattered temperature it is logical, eliminating cold to stop pain, for the common medicine for the treatment of stomach cold coldness and pain in the epigastrium, gastrofrigid vomiting: meridian distribution of property and flavor: Pungent, hot, returns spleen, stomach meridian.Major function: eliminating cold to stop pain, warming middle energizer to arrest vomiting.
The puckery intestines of nutmeg major function middle benefit gas;Promoting the circulation of qi helps digestion.Main void is rushed down;Cold dysentery;Abdominal distention;Deficiency of food vomiting;It eats not place Disappear.
[the effect of kuh-seng and effect]:
Heat-clearing and damp-drying drug;Wind dispelling insecticide.Main damp-heat dysentery;Hematochezia;Jaundice;Difficult urination;Oedema;Leukorrhagia;Pruritus vulvae;Scabies; Leprosy;Pruitus;Wet poison sore.Control toxic-heat and blood stasis, discharging fresh blood stool, jaundice, leukorrhea with reddish discharge, infantile pneumonia, infantile malnutrition due to digestive disturbances or intestinalparasites is acute flat Peach body is scorching, and anal fistula, rectal prolapse, pruitus, scabies leprosy malignant sore, the erosion of vulva is wet to itch, scrofula, scald.Trichomonas vaginitis is controlled outside.
Tourmaline health care effect
1, releasing negative oxygen ion: the negative oxygen ion that tourmaline is discharged can quickly improve air quality, promote the new old generation of cell It thanks, enhances cell viability, neutralize free radical, purification blood, pacify nerve, recover from fatigue, improve a poor appetite.In addition, anion Also being identified has the function of killing germ, purification air;
2, far infrared: the far infrared that tourmaline is discharged is discharged, human body cell and body fluid molecule can be made to generate resonance effects, Telangiectasis, Hemodynamic environment is enabled to accelerate, to improve the oxygen content of body, the macromoleculars living matter such as activation of protein increases Add the reparation and power of regeneration of tissue, improves body immunity;
3, discharge the micro-current of 0.06mA: tourmaline flows the 0.06mA substantially identical with human biological electricity because of its surface always Micro-current can supplement and adjust at any time the bioelectricity of human body, allow pathology current potential to restore normal, to play the work of sports health care With;
4, natural energy field activating cell: tourmaline crystal is known as natural solar battery.It can absorb, store the sun Luminous energy, and be allowed to be converted to electric energy (bioelectricity) and the form of thermal energy (far infrared) releases, form eternal Tourmaline Energy field supplies human body cell continuously with energy;
5, effectively block harmful radiation: tourmaline product can effectively block the harmful radiations such as unwanted electromagnetic wave, water vein waves to human body Infringement;
6, it is rich in several kinds of mineral elements: containing several kinds of mineral elements (Mg, Fe, B, Si, Ca etc.), effectively adjusting human nutrition element Balance.
Summary of the invention:
Technical solution:
To solve the above-mentioned problems, the present invention provides with treating both manifestation and root cause of disease, it can inhibit, kill germ, and can keep fit and healthy, The growth and development of infant is not influenced, rich in various trace elements, there is the treatment baby diarrhea of synergistic effect with " oral rehydration " And the cataplasm thermal sensation drug paste and preparation method of child infectious diarrhea.
The technical solution that the present invention takes to achieve the above object are as follows:
A kind of cataplasm thermal sensation drug paste, the drug paste include primary backing, and paste layer, the paste layer are arranged on the primary backing Upper setting drug ingedient includes consisting of in mass ratio: 1 ~ 3 part of raw rhubarb, 6 ~ 10 parts of Cortex Magnoliae Officinalis, and 6 ~ 10 parts of fructus piperis longi, Wu Zhu 5 ~ 8 parts of cornel, 3 ~ 6 parts of radix aucklandiae, 3 ~ 5 parts of Schisandra sphnanthera, 3 ~ 6 parts of Radix picrorrhizae, 6 ~ 10 parts of the tuber of pinellia, 3 ~ 6 parts of the dried immature fruit of citron orange, galanga 6 ~ 10 parts, 6 ~ 10 parts of myrobalan, 3 ~ 6 parts of nutmeg, 1 ~ 3 part of kuh-seng, 100 ~ 150 parts of deionized water.
As a further improvement, the drug ingedient further includes solidifying paste, the solidifying paste include in mass ratio with Lower composition: 2 ~ 5 parts of citric acid, 3 ~ 10 parts of sodium alginate, 3 ~ 10 parts of Sodium Polyacrylate, 2 ~ 5 parts of sodium carboxymethylcellulose;
As a further improvement, the drug ingedient further includes moisturizer, it in mass ratio include consisting of: glycerol 5 ~ 10 Part, 1 ~ 3 part of polyethylene glycol;
As a further improvement, the drug ingedient further includes inorganic filler, it in mass ratio include consisting of: nanometer day Right 5 ~ 10 parts of tourmaline powder, 5 ~ 10 parts of nano montmorillonite powder, 20 ~ 30 parts of fumed silica;
As a further improvement, the drug ingedient further includes transdermal penetration enhancer, in mass ratio include consisting of: azone 2 ~ 5 parts, 2 ~ 5 parts of eucalyptus oil;
As a further improvement, the drug ingedient further includes exothermic mixture, it in mass ratio include consisting of: vanillyl butyl ether 1 ~ 3 part;
As a further improvement, protective film is arranged on the paste layer, the protective film is polyethylene film, the primary backing For non-woven fabrics;
A kind of production method of cataplasm thermal sensation drug paste, method includes the following steps:
1) sodium alginate, Sodium Polyacrylate are dissolved under 60 DEG C of aqueous solutions, are added sodium carboxymethylcellulose, 60 DEG C of constant temperature with 100 ~ 200r/min stirs 30 ~ 40min;
2), fumed silica and drug solution described in claim 1 are mixed, be added citric acid, with temperature 50 ~ 60 degree, 2000 ~ 3000r/min high-speed stirred, 40 ~ 60min;
3), the liquid of above two step is mixed, tourmaline powder, montmorillonite powder is added, stirs 20 ~ 30 minutes, is then added sweet Oil, polyethylene glycol, azone, eucalyptus oil, vanillyl butyl ether were kept for 50 ~ 60 degree, with 300 ~ 500r/min stirring 30 ~ 50 minutes;
4), mixing liquid is put into ultrasonic emulsification instrument, is kept for 50 ~ 60 degree of temperature, with 40 ~ 50KHz, ultrasonic emulsification 30 ~ 50 minutes, 2 ~ 5 hours then were stood under ultraviolet disinfection lamp;
5), the medical fluid that will have been emulsified is laid on non-woven fabrics, and 1 ~ 1.5mm of thickness, 50 DEG C are dried 50 ~ 70 minutes, and polyethylene is then covered Film antiadhesion barrier, is cut into 5 × 8 square centimeters of cataplasm, and sealed package gets product cataplasm.
Beneficial effects of the present invention: unique formula of the invention, preparation method are reasonable;Belong to field of medicaments, be suitable for eliminating dampness to stop diarrhea, With middle fortune spleen.For infantile diarrhea caused by wet tired spleen soil.Symptoms include: diarrhea, loose watery stool or water sample, abdominal distension, abdominal pain, receive it is poor, Vomiting is shown in that greasy fever, pale tongue with white fur and rotaviral enteritis and noninfectious diarrhea are shown in above-mentioned patient.
Specific embodiment:
A kind of cataplasm thermal sensation drug paste, the drug paste include primary backing, and paste layer, the paste layer are arranged on the primary backing Upper setting drug ingedient includes consisting of in mass ratio: 2 parts of raw rhubarb, 8 parts of Cortex Magnoliae Officinalis, and 8 parts of fructus piperis longi, 7 parts of evodia rutaecarpa, wood It is 5 parts fragrant, 4 parts of Schisandra sphnanthera, 4 parts of Radix picrorrhizae, 8 parts of the tuber of pinellia, 5 parts of the dried immature fruit of citron orange, 7 parts of galanga, 7 parts of myrobalan, 7 parts of nutmeg, kuh-seng 7 parts, 100 parts of deionized water;
The drug ingedient further includes solidifying paste, and the solidifying paste includes consisting of in mass ratio: 4 parts of citric acid, sea 5 parts of mosanom, 6 parts of Sodium Polyacrylate, 3 parts of sodium carboxymethylcellulose;
The drug ingedient further includes moisturizer, in mass ratio includes consisting of: 7 parts of glycerol, 2 parts of polyethylene glycol;
The drug ingedient further includes inorganic filler, in mass ratio includes consisting of: 8 parts of nanometer crude tourmaline powder, 8 parts of nano montmorillonite powder, 25 parts of fumed silica;
The drug ingedient further includes transdermal penetration enhancer, in mass ratio includes consisting of: 3 parts of azone, 3 parts of eucalyptus oil;
The drug ingedient further includes exothermic mixture, in mass ratio includes consisting of: 2 parts of vanillyl butyl ether;
Protective film is set on the paste layer, and the protective film is polyethylene film, and the primary backing is non-woven fabrics;
A kind of production method of cataplasm thermal sensation drug paste, method includes the following steps:
1) sodium alginate, Sodium Polyacrylate are dissolved under 60 DEG C of aqueous solutions, are added sodium carboxymethylcellulose, 60 DEG C of constant temperature with 100 ~ 200r/min stirs 30 ~ 40min;
2), fumed silica and drug solution described in claim 1 are mixed, be added citric acid, with temperature 50 ~ 60 degree, 2000 ~ 3000r/min high-speed stirred, 40 ~ 60min;
3), the liquid of above two step is mixed, tourmaline powder, montmorillonite powder is added, stirs 20 ~ 30 minutes, is then added sweet Oil, polyethylene glycol, azone, eucalyptus oil, vanillyl butyl ether were kept for 50 ~ 60 degree, with 300 ~ 500r/min stirring 30 ~ 50 minutes;
4), mixing liquid is put into ultrasonic emulsification instrument, is kept for 50 ~ 60 degree of temperature, with 40 ~ 50KHz, ultrasonic emulsification 30 ~ 50 minutes, 2 ~ 5 hours then were stood under ultraviolet disinfection lamp;
5), the medical fluid that will have been emulsified is laid on non-woven fabrics, and 1 ~ 1.5mm of thickness, 50 DEG C are dried 50 ~ 70 minutes, and polyethylene is then covered Film antiadhesion barrier, is cut into 5 × 8 square centimeters of cataplasm, and sealed package gets product cataplasm.
Typical case:
Example one: Lee's ××, female, 2 years old, because diarrhea is gone to a doctor more than January, infant ferritic was weakness of the spleen and the stomach, every improper because catching a cold or feeding And induce diarrhea.It can be relieved every time through 5 days or more infusion treatment rears, this diarrhea caused after cold, fever before January, In certain higher level hospital through enzyme-linked immunosorbent assay, the rotavirus positive is found, rotavirus enteritis is diagnosed as.In successive intravenous infusion Potassium dehydroandrographolide succinate needle, virazole needle etc., the Chinese and Western medicines such as intramuscular injection interferon and oral dioctahedral smectite now still rush down loose stools, 5-7 times daily.Existing disease Shape: face Huang shape is thin, and tired, deficiency of food is indigestion and loss of appetite, and more than diarrhea after food, loose watery stool, indigestion is 5-7 times daily.Physical examination: 36.8 DEG C of armpit temperature, anus color is light, not red pneumonedema, and gauffer tide is viscous, and pale tongue with white fur is greasy, soft and moderate pulse.Auscultation: cardiopulmonary are without exception, borborygmus Sound is active, microscopy of defecating: fat globule ++, the visual field leucocyte 1-2/, red blood cell (-).Diagnosis: cold-dampness type diarrhea, syndrome of spleen deficiency are obvious. Cataplasm thermal sensation drug paste outer patch umbilical region of the present invention is applied alone.Very night times of defecation is reduced.It checks within second day, times of defecation obviously subtracts Few, stool gradually shapes, and infant appetite is enhanced, and 3 patches are used in conjunction and went to a doctor later, and stool forming, chromaticness is normal, and 1-2 times/day, Microscopy of defecating is normal, all disease recoveries from illness.Follow-up after 3 months, infant diarrhea do not recur again.
Example two: Zhao's ××, male, 9 months, because infant diarrhea is gone to a doctor over 2 days with nasal mucus clear nasal discharge.Existing symptom: paroxysm is cry and screamed, intestines It is loose stool after ring, thin, 8-9 times daily, the light folder foam of color of defecating, indigestion and loss of appetite, deficiency of food, nasal congestion, cough.Physical examination: armpit temperature 36.9 DEG C, anus color is light, and gauffer tide is viscous, and abdomen is soft, pale tongue, and tongue fur is thin white.Auscultation: cardiopulmonary are without exception, bowel sounds active, stool routine examination (-).Diagnosis: wind-cold type diarrhea.It is applied alone cataplasm thermal sensation drug paste of the present invention to be applied with ZHONGWAN acupoint, very night number is reduced, and second day multiple It looks into, has lined up shape stool once, nasal congestion mitigates, and with after 1 patch, all diseases are fully recovered.Follow-up after half a month, infant diarrhea is without multiple Hair.
Example three: left ××, male, 5 years old, infant ferritic was weakness of the spleen and the stomach, and last night is modern because eating watermelon again after excess of being satiated with food in feast Morning vomits 2 times, diarrhea 3 times.Loose watery stool accompanies indigestion swill.Existing symptom: sallow complexion, body is thin, and mind is tired Power, do not feel like eating.Physical examination: 36.9 DEG C of armpit temperature, abdominal fullness and distention pain, anus color is light, and lip pale tongue, whitish tongue is greasy, and arteries and veins is thin and slides.It listens Examine: cardiopulmonary are without exception, and gurgling sound is hyperfunction.Stool microscopy has fat drop.Diagnosis: cold diarrhea, spleen deficiency is stagnant to be proved to show.It is applied alone The outer emplastrum of the present invention is applied with TIANSHU acupoint (bilateral), and very night times of defecation is reduced, and vomiting, abdominal pain disappears.It checks within second day, has lined up Shape stool is primary, and appetite increases, and abdominal distension disappears.Again with after 2 patches, all diseases are fully recovered, and stool microscopy is normal.Follow-up after 2 months is suffered from Youngster's diarrhea is without recurrence.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (8)

1. a kind of cataplasm thermal sensation drug paste, it is characterised in that: the drug paste includes primary backing, and lotion is arranged on the primary backing Layer, drug ingedient is set on the paste layer, in mass ratio includes consisting of: 1 ~ 3 part of raw rhubarb, 6 ~ 10 parts of Cortex Magnoliae Officinalis, Bi 6 ~ 10 parts of the roots of grass, 5 ~ 8 parts of evodia rutaecarpa, 3 ~ 6 parts of radix aucklandiae, 3 ~ 5 parts of Schisandra sphnanthera, 3 ~ 6 parts of Radix picrorrhizae, 6 ~ 10 parts of the tuber of pinellia, the dried immature fruit of citron orange 3 ~ 6 parts, 6 ~ 10 parts of galanga, 6 ~ 10 parts of myrobalan, 3 ~ 6 parts of nutmeg, 1 ~ 3 part of kuh-seng, 100 ~ 150 parts of deionized water.
2. a kind of cataplasm thermal sensation drug paste according to claim 1, it is characterised in that: the drug ingedient further includes coagulating Paste, the solidifying paste includes consisting of in mass ratio: 2 ~ 5 parts of citric acid, 3 ~ 10 parts of sodium alginate, Sodium Polyacrylate 3 ~ 10 parts, 2 ~ 5 parts of sodium carboxymethylcellulose.
3. a kind of cataplasm thermal sensation drug paste according to claim 1, it is characterised in that: the drug ingedient further includes protecting Humectant includes consisting of: 5 ~ 10 parts of glycerol, 1 ~ 3 part of polyethylene glycol in mass ratio.
4. a kind of cataplasm thermal sensation drug paste according to claim 1, it is characterised in that: the drug ingedient further includes nothing Machine filler includes consisting of: 5 ~ 10 parts of nanometer crude tourmaline powder, 5 ~ 10 parts of nano montmorillonite powder, gas phase in mass ratio 20 ~ 30 parts of silica.
5. a kind of cataplasm thermal sensation drug paste according to claim 1, it is characterised in that: the drug ingedient further includes Skin penetrating agent includes consisting of: 2 ~ 5 parts of azone, 2 ~ 5 parts of eucalyptus oil in mass ratio.
6. a kind of cataplasm thermal sensation drug paste according to claim 1, it is characterised in that: the drug ingedient further includes hair Thermit powder includes consisting of: 1 ~ 3 part of vanillyl butyl ether in mass ratio.
7. a kind of cataplasm thermal sensation drug paste according to claim 1, it is characterised in that: protection is arranged on the paste layer Film, the protective film are polyethylene film, and the primary backing is non-woven fabrics.
8. a kind of cataplasm thermal sensation drug paste and preparation method thereof, it is characterised in that: method includes the following steps:
1) sodium alginate, Sodium Polyacrylate are dissolved under 60 DEG C of aqueous solutions, are added sodium carboxymethylcellulose, 60 DEG C of constant temperature with 100 ~ 200r/min stirs 30 ~ 40min;
2), fumed silica and drug solution described in claim 1 are mixed, be added citric acid, with temperature 50 ~ 60 degree, 2000 ~ 3000r/min high-speed stirred, 40 ~ 60min;
3), the liquid of above two step is mixed, tourmaline powder, montmorillonite powder is added, stirs 20 ~ 30 minutes, is then added sweet Oil, polyethylene glycol, azone, eucalyptus oil, vanillyl butyl ether were kept for 50 ~ 60 degree, with 300 ~ 500r/min stirring 30 ~ 50 minutes;
4), mixing liquid is put into ultrasonic emulsification instrument, is kept for 50 ~ 60 degree of temperature, with 40 ~ 50KHz, ultrasonic emulsification 30 ~ 50 minutes, 2 ~ 5 hours then were stood under ultraviolet disinfection lamp;
5), the medical fluid that will have been emulsified is laid on non-woven fabrics, and 1 ~ 1.5mm of thickness, 50 DEG C are dried 50 ~ 70 minutes, and polyethylene is then covered Film antiadhesion barrier, is cut into 5 × 8 square centimeters of cataplasm, and sealed package gets product cataplasm.
CN201811140008.2A 2018-09-28 2018-09-28 A kind of cataplasm thermal sensation drug paste and preparation method thereof Pending CN109364209A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559276A (en) * 2019-09-09 2019-12-13 左耀武 intelligent system plaster for conditioning physique and preventing and treating various types of diarrhea and preparation method
CN111568884A (en) * 2020-06-05 2020-08-25 安徽省昊祥药业有限公司 Method for preparing Chinese medicinal patch for external use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110559276A (en) * 2019-09-09 2019-12-13 左耀武 intelligent system plaster for conditioning physique and preventing and treating various types of diarrhea and preparation method
CN111568884A (en) * 2020-06-05 2020-08-25 安徽省昊祥药业有限公司 Method for preparing Chinese medicinal patch for external use

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Application publication date: 20190222