CN110292626A - A kind of emulsifiable paste and preparation method thereof for treating tinea pedis - Google Patents

A kind of emulsifiable paste and preparation method thereof for treating tinea pedis Download PDF

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Publication number
CN110292626A
CN110292626A CN201910706287.2A CN201910706287A CN110292626A CN 110292626 A CN110292626 A CN 110292626A CN 201910706287 A CN201910706287 A CN 201910706287A CN 110292626 A CN110292626 A CN 110292626A
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China
Prior art keywords
parts
emulsifiable paste
preparation
tinea pedis
treating tinea
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CN201910706287.2A
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Chinese (zh)
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景进省
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Zhengzhou Ren An Tang Medicine Technology Co Ltd
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Zhengzhou Ren An Tang Medicine Technology Co Ltd
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Priority to CN201910706287.2A priority Critical patent/CN110292626A/en
Publication of CN110292626A publication Critical patent/CN110292626A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Abstract

The present invention relates to a kind of traditional Chinese medicine emulsifiable pastes and preparation method thereof, are specifically related to a kind of emulsifiable paste and preparation method thereof for treating tinea pedis.Chinese medicine used by emulsifiable paste of the present invention is through being selected meticulously with saltcake, kuh-seng, rhizoma atractylodis, Cortex Phellodendri, the fruit of summer cypress, more than 10 medicinal material such as frutus cnidii is traditional Chinese medicine emulsifiable paste made of primary raw material, will said medicine carry out scientific combination after make each efficacy of drugs generate synergistic effect, have effects that eliminating dampness wind-dispelling, desinsection be antipruritic, Inflammation Zhijing.To treat pruitus, sore swollen toxin, eczema wet sore, all diseases of warts occur.By a kind of emulsifiable paste provided by the embodiments of the present application, tinea pedis can be quickly treated, and safely and effectively, prevents from recurring, the drug which uses is common to be easy to get, low in cost significant in efficacy, the deep approval by many patients.

Description

A kind of emulsifiable paste and preparation method thereof for treating tinea pedis
Technical field
The present invention relates to a kind of traditional Chinese medicine emulsifiable paste and preparation method thereof, it is specifically related to a kind of emulsifiable paste for treating tinea pedis and its system Preparation Method.
Background technique
Tinea pedis be that fungal infection causes, skin lesion is often that first unilateral (i.e. single foot) occurs, after several weeks or several months Just opposite side is arrived in infection.Blister mainly appears on toe abdomen and toe side, is most commonly between three or four toes, and vola also may occur in which, to be deep in property Phlysis can gradually be fused into bleb.The skin lesion of tinea pedis has a feature, i.e. clear border, can gradually extend to the outside.Because of disease Feelings development or scratching may occur in which that rotten to the corn, sepage has seriously affected people's lives quality even warts etc., occurs in bacterium infection And health.
And mainly there are partial smearing antifungal, oral medication and Chinese herbal medicine pedicure three to the processing method of tinea pedis at present Kind.But antifungal currently sold on the market injures greatly human skin mostly based on chemical raw material, and high recurrence rate; Although oral medication effect is good, many side reactions can be brought, easily body is damaged;Using some civil methods or in Herbal medicine bubble foot to boil water, the period is long, and curative effect is not good enough, and inconvenient to use.And the compound preparation for using pure natural Chinese herbal medicine to prepare is Generally acknowledged the most safely and effectively treats one of tinea pedis method, is also praised highly by dermatologist.
Therefore it provides a kind of emulsifiable paste of safe and efficient treatment tinea pedis, can not only make up existing treatment tinea pedis method Shortcoming can be simultaneously reached better anti-bacterial, anti-itching effect, perplex people no longer by tinea pedis.
Summary of the invention
Based on the above issues, the purpose of the present invention is to provide a kind of emulsifiable pastes for treating tinea pedis, extract containing natural component Object has better anti-bacterial, anti-itching effect.Another object of the present invention is to provide a kind of preparation sides of emulsifiable paste for treating tinea pedis Method.Drug of the present invention is the plaster (parts by weight) being boiled into following raw material medicaments by ad hoc approach: 10~15 parts of saltcake, kuh-seng 10~ 30 parts, 10~30 parts of rhizoma atractylodis, Cortex Phellodendri 10~15 parts of g, 10~30 parts of the fruit of summer cypress, 10~15 parts of Chinese prickly ash, 10~30 parts of frutus cnidii, Wu 10~15 parts of the fruit of medicinal cornel, 10~30 parts of ginger, 10~15 parts of aluminite, 10~30 parts of smilax.
Manufacture craft
Medicine-feeding is added to blend in grinder and be ground, and grinding temperature is 80-100 DEG C, is stirred after ground Processing is mixed, speed of agitator is 100-300 revs/min, and milling time is 1-1.2 hours;Mixture was carried out by filter screen Mixed liquor is carried out high-temperature heating treatment by filter processing, and temperature control is at 100-120 degrees Celsius, and heating time, control was at 30-40 points Clock, and be stirred during heating, mixed liquor is made thick.The finished product made is subjected to cooling treatment simultaneously It is sealed in Bottle & Can.Function: eliminating dampness wind-dispelling, desinsection be antipruritic, Inflammation Zhijing, to be suitable for pruitus, sore swollen toxin, eczema wet There are all diseases of warts in sore.
In various medicinal materials of the invention, saltcake: taste is salty, bitter, cold in nature.Return stomach, large intestine channel.Relieving constipation by purgation, moistening for dryness and softening hard mass, clearly Fire detumescence.Stagnant for real heat, abdomen expires distending pain, dry feces, acute appendicitis swelling and pain;Acute mastitis, hemorrhoid gall are controlled outside.Kuh-seng: bitter, property It is cold.Return heart, liver, stomach, large intestine, bladder meridian.Heat-clearing and damp-drying drug, desinsection, diuresis.For hot dysentery, hematochezia, jaundice urodialysis, leukorrhea with reddish discharge, Swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, castor control trichomonas vaginitis outside.Rhizoma atractylodis: acrid flavour, hardship, it is warm-natured.Returns spleen, Stomach, Liver Channel.It is drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight.For damp retention in middle-jiao, abdominal fullness and distention, diarrhea, oedema, tinea pedis impotence is preesed, rheumatism Numbness pain, anemofrigid cold, yctalopia, eyes dusk are puckery.Cortex Phellodendri: bitter, it is cold in nature.Kidney, bladder meridian.There are heat-clearing and damp-drying drug, purging intense heat, except steaming, removing toxic substances The effect for the treatment of sore.For damp-heat dysentery, jaundice and reddish urine, leukorrhagia pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis impotence is preesed, and hectic fever due to yin labor heat, night sweat is lost Essence, sore swollen toxin, eczema wet sore.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing yin and lessening fire.For fire excess from yin deficiency, night sweat hectic fever due to yin.The fruit of summer cypress: acrid flavour, hardship, property It is cold.Return kidney, bladder meridian.Clearing heat and promoting diuresis, dispelling wind and arresting itching.For difficulty and pain in micturition, pruritus vulvae leukorrhagia, rubeola, eczema, pruitus.Snake Machine tool: acrid flavour, hardship, it is warm-natured.Return kidney channel.Eliminating dampness wind-dispelling, desinsection is antipruritic, warming kidney and enhancing body.For pruritus vulvae leukorrhagia, eczema itch are wet Numbness pain in the loins, impotence due to deficiency of the kidney, uterus cold infertile.Chinese prickly ash: acrid flavour, it is warm-natured.Returns spleen, stomach, kidney channel.Warm in pain, desinsection are antipruritic.For gastral cavity Abdomen crymodynia, vomiting and diarrhea, abdominal pain due to enterositosis;External application: eczema, pruritus vulvae.Evodia rutaecarpa: acrid flavour, hardship, property heat.Return liver, spleen, stomach, kidney channel. There is the effect of eliminating cold to stop pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For jueyin headache, cold hernia stomachache, the disturbance of lower legs due to pathogenic cold and dampness, dysmenorrhea, gastral cavity Abdominal distention and pain vomits acid regurgitation, Diarrhoea.Ginger: acrid flavour, slightly warm in nature.Return lung, spleen, stomach meridian.Relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, warm lung Cough-relieving, removing toxic substances.Anemofrigid cold, taste sympotoms caused by cold factors, gastrofrigid vomiting, lung cold cough, solving toxin of fish and crab.Aluminite: external application can detoxify desinsection, dry It is wet antipruritic;Interior hemostasis, antidiarrheal, resolving sputum.The major functions: apoplexy;Epilepsy;Sore throat;Scabies wet sore;Swollen ulcer drug;Scald;Dispute Raw sore;Belepharitis ciliaris eye;Ting discharging ear;Polyp in nose;Sore hemorrhoid pain;Metrorrhagia and metrostaxis;Bleeding from five sense organs or subcutaneous tissue;Bleeding due to trauma;Nine dysentery of chronic diarrhea;Leukorrhagia yin Itch;Rectal prolapse;Metroptosis etc..Smilax: it is sweet, light, it puts down.Return liver, stomach meridian.Removing toxic substances, dehumidifying is easing joint movement.Syphilis and mercury poisoning Caused limbs muscular constricture, arthralgia and myalgia;Damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle swells, scrofula, scabies.
Fructus Cnidii powder: warming yang for dispelling cold, eliminating dampness is antipruritic, controls running sore, is born in brothers, all over, and root is made swollen firmly, itches pain very.
Xiaoshifanshi powder: clearing heat and expelling damp adds kuh-seng heat-clearing and damp-drying drug, rhizoma atractylodis dispelling dampness with bitter and warm-natured drugs, fruit of summer cypress clearing heat and expelling damp, Chinese prickly ash temperature Positive eliminating dampness.
Kuh-seng aluminite soup: heat-clearing and damp-drying drug is antipruritic.
Tinea pedis can be treated using the emulsifiable paste, removes pathogenic bacteria, alleviate symptom and prevents from recurring, is also answered with toenail tinea person It treats simultaneously.Under normal circumstances based on external medication, follows the doctor's advice, adheres to course of therapy.

Claims (4)

1. a kind of emulsifiable paste and preparation method thereof for treating tinea pedis, it is characterised in that be following material compositions and weight proportion: saltcake 10~15 parts, 10~30 parts of kuh-seng, 10~30 parts of rhizoma atractylodis, Cortex Phellodendri 10~15 parts of g, 10~30 parts of the fruit of summer cypress, 10~15 parts of Chinese prickly ash, 10~30 parts of frutus cnidii, 10~15 parts of evodia rutaecarpa, 10~30 parts of ginger, 10~15 parts of aluminite, 10~30 parts of smilax.
2. a kind of emulsifiable paste and preparation method thereof for treating tinea pedis as described in claim 1, it is characterised in that the side A and the side's B raw material Ingredient and weight are: saltcake 10g, kuh-seng 24g, rhizoma atractylodis 24g, Cortex Phellodendri 10g, fruit of summer cypress 30g, Chinese prickly ash 10g, frutus cnidii 30g, Wu Zhu Cornel 12g, ginger 24g, aluminite 10g, smilax 30g.
3. a kind of emulsifiable paste and preparation method thereof for treating tinea pedis as described in claim 1, it is characterised in that preparation method: medicine-feeding Addition is blended in grinder and is ground, and grinding temperature is 80-100 DEG C, is stirred after ground, and stirring turns Speed is 100-300 revs/min, and milling time is 1-1.2 hours, crosses 100~120 meshes, it is spare to obtain medicinal powder;Mixture is passed through Filter screen is filtered processing, and mixed liquor is carried out high-temperature heating treatment, and temperature control is at 100-120 degrees Celsius, heating time Control is stirred at 30-40 minutes, and during heating, mixed liquor is made thick.The finished product that will be made It carries out cooling treatment and is sealed in Bottle & Can.
4. a kind of emulsifiable paste for treating tinea pedis as described in claim 1 and preparation method thereof is in pruitus, sore swollen toxin, eczema Application in all diseases of wet sore, warts.
CN201910706287.2A 2019-08-01 2019-08-01 A kind of emulsifiable paste and preparation method thereof for treating tinea pedis Pending CN110292626A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730505A (en) * 2021-09-23 2021-12-03 重庆市雪英服装有限公司 Deodorant beriberi treating traditional Chinese medicine composition and deodorant socks

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985975A (en) * 2005-12-23 2007-06-27 汪婷 Chinese medicine for treating tinea pedis by soaking feet
CN103028107A (en) * 2012-12-27 2013-04-10 金根苗 Externally applied medicine for treating beriberi and preparation method of externally applied medicine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985975A (en) * 2005-12-23 2007-06-27 汪婷 Chinese medicine for treating tinea pedis by soaking feet
CN103028107A (en) * 2012-12-27 2013-04-10 金根苗 Externally applied medicine for treating beriberi and preparation method of externally applied medicine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王付: "《方剂学临床应用要旨》", 31 August 2013, 人民军医出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730505A (en) * 2021-09-23 2021-12-03 重庆市雪英服装有限公司 Deodorant beriberi treating traditional Chinese medicine composition and deodorant socks

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