CN109364113A - A kind of composition and purposes of resveratrol and Chinese medical extract - Google Patents
A kind of composition and purposes of resveratrol and Chinese medical extract Download PDFInfo
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- CN109364113A CN109364113A CN201811341546.8A CN201811341546A CN109364113A CN 109364113 A CN109364113 A CN 109364113A CN 201811341546 A CN201811341546 A CN 201811341546A CN 109364113 A CN109364113 A CN 109364113A
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- resveratrol
- chinese medical
- medical extract
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Abstract
The invention belongs to health care product manufacture fields, a kind of specifically disclosed resveratrol traditional Chinese medicine extract composition, it is resveratrol 0.75-2.5% that it is by resveratrol and Chinese medical extract by weight percentage, Chinese medical extract 97.5-99.25% is made, preparation method is to take successively gradually to be progressively increased Chinese medical extract is added by equivalent method of progressively increasing with the lesser resveratrol of weight/power ratio, it is fully ground to uniform, is sieved to obtain the final product.There is beneficial effect that is anti-oxidant, removing free radical and antiviral, antiallergic action and enhancing immune function using resveratrol, with with benefiting qi and removing blood stasis, menstruation-regulating and speckle-dispelling, nourish the Chinese traditional medicine composition of skin effect, damage to prevention and treatment free radical to skin, it promotes blood circulation, promoting skin cell development has preferable assisting in preventing and treating effect.Routinely tablet, capsule, granule, oral solution or wine product are made as the purposes for preparing health care product or as the purposes of the additive prepared in cosmetics in technique to the composition.
Description
Technical field
The present invention relates to pharmaceutical preparation and/or health food manufacture fields, and in particular to one kind is by resveratrol and Chinese medicine
The pharmaceutical composition and purposes of extract composition.
Background technique
Resveratrol (Resveratrol) is also known as white black false hellebore phenol, and resvertrol is a kind of chemopreventive agent of tumour,
It is to prevent and treat the chemopreventive agent of atherosclerosis, cardiovascular and cerebrovascular disease to platelet aggregation is reduced.Resveratrol mesh
Preceding embody a concentrated expression of on clinical medicine inhibits monoamine oxidase, anti-oxidant, removing free radical, and platelet aggregation-against is antitumor
Effect and purposes.Resveratrol is the natural being present in plant, plays the oxidation resistant mechanism of action and is mainly
It removes or free radical is inhibited to generate, inhibit lipid peroxide, adjust anti-oxidant related enzyme activity etc..Harvard University professor in 2003
DavidSinciair and its team increase the service life of saccharomycete, this hair the study found that resveratrol can activate acetylase
People are now excited to the upsurge of resveratrol research on anti-senescence.Up to the present, there is research it has been confirmed that resveratrol has
The effect of extending yeast, nematode, drosophila and low fish service life further demonstrates its resveratrol with anti-aging effects.
To the adjustment effect of immune system, the resveratrol of various dose is observed to machine by establishing immunosuppression model mouse in high road etc.
The influence of body immunity function.As a result, it has been found that the macrophage that the resveratrol of various dose can significantly improve immunosuppression model mouse is thin
Born of the same parents' phagocytic rate, half hemolytic dose, body antibody forming cell number, lymphocyte transformation rate and inhibition mouse auricle swelling
(i.e. the IV type hypersensitivity of normal mouse).To normal mouse, resveratrol has no significant effect immune function, but can inhibit IV
Type hypersensitivity.
As that studies resveratrol deepens continuously, it has been found that resveratrol also has adjusting immune, antiviral, anti-
The effects of allergy, liver protection.It is added in drug, drinks or cosmetics in addition, resveratrol is used as additive, as
A kind of new type of cosmetic health care product keeps skin moisture, dispels sore class, chloasma etc. to delay the aging of people.
Since modern people's rhythm of life is accelerated, life stress is big, the variation of life pattern, and environmental pollution is to the modern times in addition
Increasing trend is also presented in some distinctive diseases accordingly in life.Such as because of insufficiency of vital energy and blood, the institutes such as qi and blood retardance or qi deficiency to blood stasis
The endocrine disturbance of cause, chloasma (blackish facial patch), freckle, butterfly macules, the yellow cases such as coarse of skin surface obviously increase, until current
There is not the therapeutic agent of definite curative effect, cause psychological pressure and mental burden to many Mies yet, even therefore generate psychology
Disease.Have effects that adjust immune, antiviral, anti-aging, anti-oxidant and effect of scavenging radical using resveratrol, in conjunction with
The traditional middle medical drugs theory in China, with benefiting qi and removing blood stasis, menstruation-regulating and speckle-dispelling, nourish skin effect Chinese traditional medicine composition, by white Chenopodiaceae
This bioactive substance of reed alcohol and traditional medicine and modern pharmaceutical technology organically combine, and form a kind of new pharmaceutical composition
Object enables the pharmaceutical composition to play the preventive and therapeutic effect of auxiliary in the treatment of above-mentioned disease.
Summary of the invention
The purpose of the present invention is to provide a kind of by resveratrol and a kind of pharmaceutical composition that Chinese medical extract forms and
Purposes.
The object of the invention is also to provide a kind of pharmaceutical composition preparation auxiliary adjustment benefiting qi and removing blood stasis, menstruation-regulating and speckle-dispelling,
It nourishes in skin drug as the purposes for preparing health care product.
The object of the invention is also to provide a kind of pharmaceutical compositions in the purposes for preparing the additive in cosmetics.
A kind of pharmaceutical composition provided by the invention, which is characterized in that it is the weight by resveratrol and Chinese medical extract
Amount percentage be resveratrol 0.75-2.5%, Chinese medical extract 97.5-99.25% composition, the Chinese medical extract press with
The preparation of lower section method: concentration is added as the ethyl alcohol of 75%(v/v) in ginseng 150g, Radix Angelicae Sinensis 450g, rhizome of chuanxiong 100g, Radix Astragali 550g
12500g impregnates 168 hours at 38-42 DEG C, leaching soaked extracting solution, and recycling ethyl alcohol obtains leaching liquor and saves backup, separately by the dregs of a decoction
It being added water to cook 3 times by 8 times, 5 times, 3 times of medicinal material weight respectively, decocting time is the 1st time 2 hours, 1 hour for the second time, third time
0.5 hour, merge 3 decoction liquors, through filtering, it is concentrated to specific gravity be 1.0 concentrate when, then with after above-mentioned recycling ethyl alcohol
Leaching liquor merges, and is further condensed into thick paste, the dry medicinal extract for being less than 5%w/w to water content.
The Chinese medical concrete is hereinafter referred to as " Chinese medical extract described in herein (or above) ".
The preparation method of the present composition, it is desirable with the lesser resveratrol of weight/power ratio by equivalent progressively increase method successively by
Step progressively increases Chinese medical extract is added, and is fully ground to uniform, is sieved to obtain the final product.
The dry drying means using under the conditions of dry technology well known in the art described above, is such as dried in vacuo, is cold
Dry or hot wind low temperature drying etc. is lyophilized, in the condition in view of avoiding or reducing the loss of effective component in Chinese medical extract, choosing
Select the drying process for avoiding the drying means of high temperature suitable for the present invention.
Routinely tablet, capsule, granule, oral solution is made as preparing health care product in technique to the pharmaceutical composition
Purposes.
The pharmaceutical composition is as the purposes for preparing wine product.
Purposes of the pharmaceutical composition as the additive prepared in cosmetics.
Ginseng, sweet, slight bitter, tepor.Returns spleen, lung, heart kidney channel.It with replenish vital energy, restore pulse, and strengthen and remove vital energy, reinforces the spleen to benefit the lung, promotes the production of body fluid
Blood-nourishing, tranquilize the mind and promote the intelligence function.Ginseng reinforces vital energy, and vigour is filled, and the motive must support, and the mind obtains rather, intelligence obtain it is clever, and have calm the nerves benefit
The effect of intelligence, for treating deficiency of heart-QI or heart kidney qi deficiency, the insomnia of the insufficiency of heart and spleen, amnesia etc..Ginseng sweet temperature, reinforces vital energy,
QI invigorating has the benefits of qi-blood tonifying with green blood, therefore can be used and control deficiency of spleen-QI and stomach-QI, changes source deficiency, the card of blood deficiency chlorosis.
Radix Angelicae Sinensis, sweet, acrid, warm.Return liver, the heart, the spleen channel.With replenishing and activating blood, regulating menstruation and relieving pain, moistening intestines and relaxing bowels function is used for blood
Empty sallow, dizziness palpitaition, irregular menstruation, amenorrhea and algomenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, intestinal dryness is just
It is secret.The sweet temperature of Radix Angelicae Sinensis, blood-nourishing qi-restoratives, for good medicine of enriching blood, thus it is available control heart-liver blood deficiency, color is sallow, dizziness palpitaition.
Rhizome of chuanxiong, it is acrid in flavour and warm in nature.Return liver, gallbladder, pericardium channel.With blood-activating and qi-promoting, wind-expelling pain-stopping function.The pungent scattered temperature of rhizome of chuanxiong is logical, function
Blood-activating and qi-promoting has the title of " gas medicine in blood " (" collected statements on the herbal foundation ").Both promoting blood circulation was promoted blood circulation, kind to control heart arteries and veins stasis blocking, chest impediment and cardialgia；Again
Promote breath and open depression analgesic, the sternal rib shouting pain by stagnation of QI due to depression of the liver are multi-purpose.Rhizome of chuanxiong is good at " lower menstruation regulating water " (" collected statements on the herbal foundation "), promoting blood circulation is adjusted
Through the excellent key medicine for cards such as irregular menstruation, dysmenorrhea, menostasis；Yi Zhi abdominal mass and abdominal pain, the function with promoting blood circulation, disease eliminating powder junction.
Radix Astragali, sweet, tepor.Return lung, the spleen channel.With tonifying Qi and lifting yang, strengthening exterior and reducing sweat, inducing diuresis for removing edema, shengjin nourishing, row is stagnant to be led to
Numbness, pus draining and toxin expelling, expelling pus and promoting granulation effect is out of strength for qi and blood, anorexia and loose stool, the sinking of qi of middle-jiao, diarrhea rectal prolapse, uterine bleeding of having blood in stool, table
Empty spontaneous perspiration, deficiency of vital energy and edema, Heat Diabetes, the sallow card of the deficiency of vital energy.The sweet tepor of Radix Astragali, benefiting qi and raising yang, lid Yin grows while yang is generating, the prosperous blood of gas
It is raw, therefore have the function of qi-supplementing, blood-engendering, long to be used for overstrain internal injury, gas loses the deficiency of blood, and deficiency of blood sun is floating, the hot flushing of flesh, the deficiency of blood of the big inability of arteries and veins
Fever card.And worry beyond measure, internal lesion caused by overexertion heart spleen, deficiency of qi and blood, sallow complexion, palpitation and insomnia person.
Above 4 kinds of Chinese medicinal compositions prepare extract, prove there is benefiting qi and removing blood stasis according to traditional Chinese medical theory, menstruation-regulating and speckle-dispelling is grown
Skin effect is supported, by modern Chinese herbal medicine theoretical research, if Radix Angelicae Sinensis is one of main ingredient in component, effective component ferulic acid be can be reduced
H2O2Content, and inhibit oxidation reaction and radical reaction in conjunction with phosphatidyl-ethanolamine, damage of the antagonism free radical to tissue,
It promotes blood circulation, promotes the effect of skin cell development.Free radical can not only be quenched in ferulic acid.But also it is raw to be adjustable human body
Reason mechanism inhibits the enzyme generated free radicals, promotes the generation for removing the enzyme of free radical.
Heterogeneity can be generated using resveratrol activity ingredient and Chinese traditional medicine composition extract, different role mechanism cooperates with
Therapeutic effect can strengthen the anti-oxidant of its drug and understand Free Radical and anti-allergy action, while promoting to adjust and exempt from
Epidemic disease function etc., these can enhance immunity function.The present invention using resveratrol have it is anti-oxidant, remove free radical and disease-resistant
Poison, antiallergic action and the beneficial effect for enhancing immune function, with benefiting qi and removing blood stasis, menstruation-regulating and speckle-dispelling nourishes skin effect
Chinese traditional medicine composition, the damage to prevention and treatment free radical to skin, promotes blood circulation, and promoting skin cell development has preferable auxiliary
Control efficiency.Using the tablet of pharmaceutical composition of the present invention preparation, capsule, once to because of the patient with chloasma caused by qi deficiency to blood stasis
10 people carry out medication clinical observation, and patient is women, and the age between 22-24 years old, takes dose and implements respectively by the present invention
Capsule made from tablet made from example 14 and embodiment 13, wherein 5 people take tablet, 5 people take capsule, take tablet
Person often takes daily 3 times each taking 3, and the person that takes capsule often takes daily 3 times, each taking 5 wherein taking 5 people of tablet at medication 90 days
3 people of chloasma disappearance, 2 people are clearly better afterwards, take 5 people of capsule after medication 90 days, chloasma 4 people of disappearance, and 1 people is obviously good
Turn.Effective percentage is 100%, wherein observation, which is taken between tablets and capsules, does not have biggish notable difference.Clinical Practice card
It is bright, pharmaceutical composition of the present invention to adjuvant treatment chloasma have good application effect, this to expand Chinese medicine clinical application,
Curative effect is improved to be of practical significance very much.
A kind of pharmaceutical composition of the invention, can according to need and be configured to different peroral dosage forms.It can be by medicine group
It closes object and pharmaceutically acceptable auxiliary material is hybridly prepared into tablet, capsule, granule, wine product etc., wherein capsule can be made
For at soft capsule and hard capsule；The wherein preferred effervescent tablet of tablet, chewable tablets, buccal tablet, because of effervescent tablet, chewable tablets, mouth
Lozenge has following advantage compared with conventional tablet: (1) convenient to take, chewable clothes, buccal, Ke Huashui, due to preparing these
A certain amount of sugared part will be added as excipient in tablet, thus in good taste, and people gladly take, and effervescent tablet adds after water self-dissolving still
Such as one glass of beverage, people is made to be happy to drink；(2) it absorbs fastly, because direct oral cavity or bubble drink ionize drug ingedient, is allowed to absorb
Fastly, bioavilability is high；(3) easy to carry, convenient transportation；Wherein the wine product can be made into white wine, yellow rice wine and beer product.
A kind of pharmaceutical composition of the present invention, can also be configured to cosmetics as needed.
Specific embodiment
It is that the present invention is further illustrated, but does not constitute any limit to the scope of the present invention by following embodiment
System.
Embodiment 1
The preparation of Chinese medical extract
Net medicinal material ginseng 150g, Radix Angelicae Sinensis 450g, rhizome of chuanxiong 100g are weighed respectively, and Radix Astragali 550g is placed in extractor, and concentration is added and is
75% ethyl alcohol 12.5kg, it is closed under the conditions of 40 DEG C to impregnate 168 hours, it was stirred 1 time, soaks every 6 hours during immersion
After bubble, soaked extracting solution recycling ethyl alcohol is obtained the another device of leaching liquor and saved backup by leaching soaked extracting solution；After alcohol is extracted
The dregs of a decoction are added 10 kilograms of pure water, and heating decocts 2 hours, leaching decoction liquor, and the dregs of a decoction add 6.25 kilograms of pure water, and heating is decocted
It boils 1 hour, leaching decoction liquor, then the dregs of a decoction is added 3.75 kilograms of pure water, heating decocts 0.5 hour, leaching decoction liquor, by 3 times
Decoction liquor merges, filtering, when concentrating the filtrate to the concentrate that specific gravity is 1.0, then merges with above-mentioned leaching liquor, further dense
After shortening thick paste into, being placed in vacuum drier and be dried under vacuum to water content is 4.5% to get Chinese medical extract.
Embodiment 2
The preparation of Chinese medical extract
Net medicinal material ginseng 150g, Radix Angelicae Sinensis 450g, rhizome of chuanxiong 100g are weighed respectively, and Radix Astragali 550g is placed in extractor, and concentration is added and is
75% ethyl alcohol 12.5kg, it is closed under the conditions of 38 DEG C to impregnate 168 hours, it was stirred 1 time, soaks every 6 hours during immersion
After bubble, soaked extracting solution recycling ethyl alcohol is obtained the another device of leaching liquor and saved backup by leaching soaked extracting solution；After alcohol is extracted
The dregs of a decoction are added 10 kilograms of pure water, and heating decocts 2 hours, leaching decoction liquor, and the dregs of a decoction add 6.25 kilograms of pure water, and heating is decocted
It boils 1 hour, leaching decoction liquor, then the dregs of a decoction is added 3.75 kilograms of pure water, heating decocts 0.5 hour, leaching decoction liquor, by 3 times
Decoction liquor merges, filtering, when concentrating the filtrate to the concentrate that specific gravity is 1.0, then merges with above-mentioned leaching liquor, further dense
After shortening thick paste into, being placed in vacuum drier and be dried under vacuum to water content is 4.8% to get Chinese medical extract.
Embodiment 3
The preparation of Chinese medical extract
Net medicinal material ginseng 150g, Radix Angelicae Sinensis 450g, rhizome of chuanxiong 100g are weighed respectively, and Radix Astragali 550g is placed in extractor, and concentration is added and is
75% ethyl alcohol 12.5kg, it is closed under the conditions of 42 DEG C to impregnate 168 hours, it was stirred 1 time, soaks every 6 hours during immersion
After bubble, soaked extracting solution recycling ethyl alcohol is obtained the another device of leaching liquor and saved backup by leaching soaked extracting solution；After alcohol is extracted
The dregs of a decoction are added 10 kilograms of pure water, and heating decocts 2 hours, leaching decoction liquor, and the dregs of a decoction add 6.25 kilograms of pure water, and heating is decocted
It boils 1 hour, leaching decoction liquor, then the dregs of a decoction is added 3.75 kilograms of pure water, heating decocts 0.5 hour, leaching decoction liquor, by 3 times
Decoction liquor merges, filtering, when concentrating the filtrate to the concentrate that specific gravity is 1.0, then merges with above-mentioned leaching liquor, further dense
After shortening thick paste into, being placed in vacuum drier and be dried under vacuum to water content is 4.0% to get Chinese medical extract.
Embodiment 4
The preparation of pharmaceutical composition
Weigh resveratrol 7.5g, set in mortar, by equivalent progressively increase method be added embodiment 1 made from Chinese medical extract 7.5g,
Be ground to uniformly, then equivalent is progressively increased middle extract 15g, grinding uniformly, by successively equivalent progressively increase Chinese medical extract based on 992.5g extremely
Full dose is 1000g, be fully ground uniformly, sieving to get.
Embodiment 5
The preparation of pharmaceutical composition
Weigh resveratrol 25g, set in mortar, by equivalent progressively increase method be added embodiment 1 made from Chinese medical extract 25g, grind
Be milled to uniformly, then equivalent is progressively increased middle extract 50g, grinding uniformly, by successively equivalent progressively increase Chinese medical extract based on 975g to full dose
For 1000g, be fully ground uniformly, sieving to get.
Embodiment 6
The preparation of pharmaceutical composition
Weigh resveratrol 20g, set in mortar, by equivalent progressively increase method be added embodiment 1 made from Chinese medical extract 20g, grind
Be milled to uniformly, then equivalent is progressively increased middle extract 40g, grinding uniformly, by successively equivalent progressively increase Chinese medical extract based on 980g to full dose
For 1000g, be fully ground uniformly, sieving to get.
Embodiment 7
The preparation of pharmaceutical composition
Weigh resveratrol 15g, set in mortar, by equivalent progressively increase method be added embodiment 2 made from Chinese medical extract 15g, grind
Be milled to uniformly, then equivalent is progressively increased middle extract 30g, grinding uniformly, by successively equivalent progressively increase Chinese medical extract based on 985g to full dose
For 1000g, be fully ground uniformly, sieving to get.
Embodiment 8
The preparation of pharmaceutical composition
Weigh resveratrol 10g, set in mortar, by equivalent progressively increase method be added embodiment 2 made from Chinese medical extract 10g, grind
Be milled to uniformly, then equivalent is progressively increased middle extract 20g, grinding uniformly, by successively equivalent progressively increase Chinese medical extract based on 990g to full dose
For 1000g, be fully ground uniformly, sieving to get.
Embodiment 9
The preparation of pharmaceutical composition
Weigh resveratrol 18g, set in mortar, by equivalent progressively increase method be added embodiment 3 made from Chinese medical extract 18g, grind
Be milled to uniformly, then equivalent is progressively increased middle extract 36g, grinding uniformly, by successively equivalent progressively increase Chinese medical extract based on 982g to full dose
For 1000g, be fully ground uniformly, sieving to get.
Embodiment 10
The preparation of pharmaceutical composition
Weigh resveratrol 17.5g, set in mortar, by equivalent progressively increase method be added embodiment 3 made from Chinese medical extract
17.5g is ground to uniformly, then equivalent is progressively increased middle extract 35g, based on grinding uniformly, by successively equivalent progressively increases Chinese medical extract
982.5g to full dose be 1000g, be fully ground uniformly, sieving to get.
Embodiment 11
The preparation of pharmaceutical composition
Weigh resveratrol 23.5g, set in mortar, by equivalent progressively increase method be added embodiment 3 made from Chinese medical extract
23.5g is ground to uniformly, then equivalent is progressively increased middle extract 47g, based on grinding uniformly, by successively equivalent progressively increases Chinese medical extract
976.5g to full dose be 1000g, be fully ground uniformly, sieving to get.
Embodiment 12
The preparation of pharmaceutical composition
Weigh resveratrol 21g, set in mortar, by equivalent progressively increase method be added embodiment 3 made from Chinese medical extract 21g, grind
Be milled to uniformly, then equivalent is progressively increased middle extract 42g, grinding uniformly, by successively equivalent progressively increase Chinese medical extract based on 979g to full dose
For 1000g, be fully ground uniformly, sieving to get.
Embodiment 13
The capsule containing following component can be produced in the usual way:
Component:
Weigh 5 pharmaceutical composition 100g of embodiment
Dextrin 50g
Starch 150g
After now starch is dried, 120 meshes are crossed, is uniformly mixed with pharmaceutical composition, using 120 mesh three times, is allowed to
It mixes well, is respectively charged into capsule, 1000 capsules are made, every weight is 0.3g.
Embodiment 14
The tablet containing following component can be produced in the usual way:
Component:
Weigh 5 pharmaceutical composition 100g of embodiment
Talcum powder 10g
Starch 390g
1000, tablet are made according to a conventional method, every sheet weight is 0.5g.
Embodiment 15
The effervescent tablet containing following component can be produced in the usual way:
Component:
Weigh 7 pharmaceutical composition 200g of embodiment
Citric acid 600g
Sodium bicarbonate 1100g
Lactose 1200g
Pharmaceutical composition and other auxiliary materials are crossed into 100 nylon meshes respectively, after then mixing in the method that equivalent is progressively increased again
100 nylon mesh are crossed, and are mixed well, with weight 5%-10% povidone ethanol solution (the dosage model that interior plus proper amount of medication allows
The polyoxyethylene sorbitan monoleate and sweetener enclosed) softwood processed, with the granulation of 20 mesh nylon mesh, 40 DEG C of drying, appropriate polyethylene glycol is added in whole grain
6000 make lubricant, and 2000 effervescent tablets are made in tabletting, and every weight is 1.55g.
Embodiment 16
The wine containing following component can be produced in the usual way:
Component:
Weigh 11 pharmaceutical composition 50g of embodiment
50 degree of white wine 950g
It takes pharmaceutical composition to be added in 50 degree of white wine, is sufficiently stirred, then place at room temperature, after closed storage 21 days, filtering, i.e.,
?.
Embodiment 17
The wine containing following component can be produced in the usual way:
Component:
Weigh 8 pharmaceutical composition 100g of embodiment
Honey 120g
Citric acid 11g
22 degree of white wine add to 1000g
Taking pharmaceutical composition, citric acid and honey to be sequentially added into suitable 22 degree of white wine makes molten, and surplus is then added
White wine stirs evenly, and is placed in room temperature dark place, after standing 1 week, is filtered, and dispenses, seals to obtain the final product.
Embodiment 18
The wine containing following component can be produced in the usual way:
Component:
Weigh 4 pharmaceutical composition 25g of embodiment
Yellow rice wine adds to 1000g
Taking pharmaceutical composition to be added in appropriate yellow rice wine makes molten, and the yellow rice wine of surplus is then added, stirs evenly, is placed in 3-5 DEG C of environment
Under, it stands 24 hours, filters, bottling is sealed to obtain the final product.
Claims (5)
1. a kind of resveratrol traditional Chinese medicine extract composition, which is characterized in that it is by resveratrol and Chinese medical extract by weight
Amount percentage is resveratrol 0.75-2.5%, and Chinese medical extract 97.5-99.25% is made,
Preparation method: it takes and is successively gradually progressively increased traditional Chinese medicine extraction is added by equivalent method of progressively increasing with the lesser resveratrol of weight/power ratio
Object is fully ground to uniform, is sieved to obtain the final product；Wherein the Chinese medical extract is prepared as follows: by ginseng 150g, Radix Angelicae Sinensis
450g, rhizome of chuanxiong 100g, Radix Astragali 550g are added the ethyl alcohol 12500g that concentration is 75%v/v and impregnate 168 hours at 38-42 DEG C, filter
Soaked extracting solution is taken, recycling ethyl alcohol obtains leaching liquor and saves backup, and the dregs of a decoction are separately pressed to 8 times of medicinal material weight, 5 times, 3 extraordinarily decoctings respectively
It boils 3 times, decocting time is the 1st time 2 hours, and second 1 hour, third time 0.5 hour merged 3 decoction liquors, filtered, and is passed through
When being concentrated into the concentrate that specific gravity is 1.0, then merge with the leaching liquor after above-mentioned recycling ethyl alcohol, be further condensed into thick paste,
The dry medicinal extract for being less than 5%w/w to water content.
2. routinely tablet, capsule, particle is made in technique to resveratrol traditional Chinese medicine extract composition as described in claim 1
Agent, oral solution or wine product are as the purposes for preparing health care product.
3. use of the resveratrol traditional Chinese medicine extract composition as described in claim 1 as the additive prepared in cosmetics
On the way.
4. the purposes of composition according to claim 2, for preparing effervescent tablet, chewable tablets, buccal tablet.
5. the purposes of composition according to claim 2, for preparing white wine, yellow rice wine and beer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811341546.8A CN109364113A (en) | 2018-11-12 | 2018-11-12 | A kind of composition and purposes of resveratrol and Chinese medical extract |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110484416A (en) * | 2019-09-17 | 2019-11-22 | 陈夕成 | A kind of Menopause health liquor and its preparation method and application |
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| CN1413619A (en) * | 2002-07-22 | 2003-04-30 | 中国人民解放军第四军医大学药物研究所 | Sheqi facial appearance capsule and its preparation technology |
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Application publication date: 20190222 |