CN109315774A - A kind of fructus lycii astragalus health-care food and preparation method thereof - Google Patents
A kind of fructus lycii astragalus health-care food and preparation method thereof Download PDFInfo
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- CN109315774A CN109315774A CN201811322485.0A CN201811322485A CN109315774A CN 109315774 A CN109315774 A CN 109315774A CN 201811322485 A CN201811322485 A CN 201811322485A CN 109315774 A CN109315774 A CN 109315774A
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- fructus lycii
- radix astragali
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- 239000011669 selenium Substances 0.000 description 1
- 208000013223 septicemia Diseases 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 210000004158 stalk cell Anatomy 0.000 description 1
- 229940032147 starch Drugs 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 1
- 235000021286 stilbenes Nutrition 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of fructus lycii astragalus health-care food, each component including following parts by weight: 27-32 parts of Astragalus Root P.E, 42-50 parts of wolfberry fruit extract, 9-13 parts of spirulina freeze-dried powder, 5-9 parts of filler, 3-5 parts of lubricant, 1-2 parts of essence.Fructus lycii astragalus health-care food prepared by the present invention is full of nutrition, is rich in polysaccharides and astragalus polyose, can enhance the immunity of human body well.
Description
Technical field
The invention belongs to health product technology fields, and in particular to a kind of fructus lycii astragalus health-care food and preparation method thereof.
Background technique
With society and economic progress, the improvement of people's living standards, scientific and technical development, the change of disease pattern
And the pursuit to good health and a long life, the functional food of strengthen immunity gradually everybody deep heart, people have started from treating again
Steering prevents again, this will be greatly promoted the development of the functional food of strengthen immunity.21 century will be that functional food is big
The century displayed one's abilities.China possesses the huge treasure-house of this functional food of Chinese herbal medicine and other characteristic resources, we should combine
The impetus of the functional food development trend of strengthen immunity and China's development is made great efforts to excavate these precious resources, be developed
The functional food of strengthen immunity with Chinese characteristics, to obtain due status in fierce international competition.According to generation
The investigation of boundary's health organization, the whole world is there are about 35% or more people is in a state of fatigue, especially middle-aged male crowd fatigue state person
Up to 60%-75%.Medical expert points out that a series of ill symptoms can be led to by continuing over fatigue, generates " burnout syndrome ".
Due to the naturally-aged of operating pressure, family burden and human organ, more and more people feel that physical condition is not equal to before,
It is easy fatigue, therefore which type of product can alleviate human-body fatigue sense with and have been to be concerned by more and more people.
Fructus lycii is a kind of rare Chinese medicine, nutritional ingredient very abundant, and has very high drug value, not only iron content, phosphorus, calcium
Equal substances, but also containing a large amount of sugared, fatty, protein and amino acid, polysaccharide pigment, vitamin, sterol, glucoside etc., there is profit
Lung clearing liver, nourshing kidney, QI invigorating, production of sperm, supporing yang, wind-dispelling, improving eyesight, strengthening the bones and muscles function, also containing there is good medical treatment to protect human body
The polysaccharide of strong effect and the organic germanium for being beneficial to human intelligence exploitation.Polysaccharides molecular weight be 22~25kD, by arabinose,
6 kinds of glucose, galactolipin, mannose, xylose, rhamnose monosaccharide components compositions, polysaccharides have enhancing body immunity, resist
The effects of tumour, anti-aging and antifatigue effect, in addition there are also apparent reducing blood lipid, hypoglycemic, resist oxygen lack.Chinese wolfberry fruit in addition to
Other than basic nutrition ingredient with fruit, also containing bioactive substances such as Flavonoids, polysaccharide.Total flavonoids of lycium barbarum L
With removing, free radical, anti-oxidant, anti-mutation, antitumor, antibacterial, antiviral and adjusting is immune, treatment of vascular is hardened, hypoglycemic
Etc. functions, improve the purpose of flavones.But there are content of reducing sugar height, nutritional ingredient human body utilization rates for existing fructus lycii product
Low problem.
Tonifying Qi and lifting yang, strengthening exterior and reducing sweat, inducing diuresis to remove edema, apocenosis, sore are had by the Radix Astragali that pharmaceutical industry is known as " ten medicines, eight stilbene "
The effect of myogenic, has the function of anti-oxidant, antiviral, mitigation immunologic mjury and immune bidirectional modulation, is conventionally used to improve people
Body immunity and other effects.Astragalus polyose is that water solubility made of the extracted dry root of Radix Astragali or Astragalus membranacus, concentration, purifying is miscellaneous
Polysaccharide is one of main active of Radix Astragali.In faint yellow, powder exquisiteness, uniform free from admixture, with hygroscopicity.Radix Astragali is more
Sugar is made of hexuronic acid, glucose, fructose, rhamnose, arabinose, galacturonic acid and glucuronic acid etc., can be used as
Immunopotentiating agent or regulator, can increase the non-specific resistivity of body, and clinic is commonly used for immunopotentiator while having
Antiviral and antitumor, anti-aging, anti-radiation, resisting stress, it is anti-oxidant the effects of, be widely used in medicine and functional food field,
It has a vast market foreground.But that there are recovery rates is lower for existing astragalus polyose extracting method, purity is low, polysaccharide properties not
Stablize, the shortcomings such as loss of effective components is more.
Protein is equivalent to 6 times of wheat containing up to 60~70% in spirulina, and 4 times of pork, 3 times of the flesh of fish, chicken
5 times of egg, 2.4 times of cheese, and digestibility is up to 95% or more.Its distinctive phycocyanin, it is thin to can be improved lymph
Cytoactive enhances human immunity, therefore acquires a special sense to gastrointestinal disease and hepatopath's rehabilitation.In spirulina vitamin and
The extremely rich reality of content of mineral substances, including VB1, VB2, VB6, VB12, VE, VK etc., and containing zinc, iron, potassium, calcium, magnesium, phosphorus, selenium, iodine etc.
Microelement, biological zinc, iron ratio need unanimously, to be easiest to be absorbed by the body, can quickly improve small substantially with Human Physiology
Child's apositia improves appetite.Its carotene carotene content is 1.5 times of carrot, and VB12 content is 4 times of pork liver, and iron content is spinach
23 times of dish are the most abundant food of iron content, and therefore, spirulina has positive effect to prevention and treatment anaemia.One gram of spirulina is equal to 1
The summation of vitamin and mineral in kilogram all kinds of veterinary antibiotics.Spirulina contains a large amount of gamma-Linolenic acid, this is a kind of people
The desirable material that unsaturated fatty acid necessary to body is brain tonic and intelligence development, removes blood lipid, adjusts blood pressure, reducing cholesterol.Spirulina
In spirulina polysaccharide have Antiradiation injury and improve Radiotherapy chemotherapy caused by side reaction effect, therefore to tumor patient be eat
Treat good merchantable brand.Spirulina Determination of Chlorophyll content is extremely abundant, is 10 times of common vegetable content or more, to promoting human consumption, in
With septicemia element and improvement allergic constitution, eliminating internal organ inflammation etc. has positive effect.Fat content only has in spirulina
5%, and it is cholesterol-free, human body can be made to avoid taking in excessive heat when supplementing necessary albumen.
The present invention is opened using the mutual enhancing and complementarity, extraction of polysaccharides, the compatibility advantage of astragalus polyose and function
The fructus lycii of sending, Huangqi Compound extract, can be used as Organism immunoregulation agent, improve animal body immunity and control animal
There is significant effect in terms of immunosuppressant disease.
Summary of the invention
It is in view of the drawbacks of the prior art and insufficient, the present invention provides a kind of fructus lycii Radix Astragali strengthen immunity health food,
The product has effects that increase body immunity.
To achieve the above object, the technical solution of the present invention is as follows:
A kind of fructus lycii Radix Astragali strengthen immunity health food, each component including following parts by weight:
27-32 parts of Astragalus Root P.E, 42-50 parts of wolfberry fruit extract, 9-13 parts of spirulina freeze-dried powder, 5-9 parts of filler, profit
3-5 parts of lubrication prescription, 1-2 parts of essence.
Preferably, the filler is that can be selected from starch, dextrin, Icing Sugar, honey element, mannitol, xylitol, microcrystalline cellulose
One or more of element.
Preferably, the lubricant is one or more of magnesium stearate, talcum powder, sodium benzoate.
Further, the preparation method of the Astragalus Root P.E, specifically includes the following steps:
(1) it pre-processes: will be crushed after fresh Radix Astragali rhizome washing, removal impurity through low temperature liquid nitrogen, be rapidly added 5-8 times
The water of quality impregnates 2-3h under 55-60 DEG C of water bath condition；
(2) ferment: into Radix Astragali, inoculating compound bacterium agent ferments；
(3) ultrasonic extraction: being added 3-5 times of volume of water in the fermentation liquid obtained to step (2) and stir and evenly mix, and is then added poly-
Sorb ester -80 simultaneously makes its final concentration of 0.3-0.5%, is then ultrasonically treated 1.5-2h under 45-55 DEG C of water bath condition, filters
To filtrate and filter residue, the water of 3-5 times of weight of filter residue is added, repeats to extract 2-3 times, and merge obtained filtrate is filtered；
(4) separate: the filtrate that step (3) are merged separates by macroreticular resin, takes unadsorbed position, film filtering retention
The isolate of 150kD molecular size range, concentration, spray drying obtain Astragalus Root P.E.
Further, in step (2), concentration of the composite bacteria agent in astragalus root fermentation liquor is 0.1-0.2%, described compound
Microbial inoculum is mixed by Bifidobacterium and saccharomyces cerevisiae according to 2:1 weight ratio；Anaerobism hair is carried out under the conditions of 35-40 DEG C, 5 pH
Ferment 2-3 days.
Further, the preparation method of the wolfberry fruit extract, specifically includes the following steps:
(1) it ferments: being inoculated with fermentation Chinese wolfberry fruit liquid after fructus lycii is pre-processed, ferment at a temperature of 28-32 DEG C after mixing
3-5 days；
(2) it sterilizes: the fructus lycii after fermentation is sterilized；
(3) extract: to after sterilizing fructus lycii be added 6-8 times of quality water, impregnate 5-8h after under 45-55 DEG C of water bath condition
It is ultrasonically treated 1.5-2h, suction filtration obtains filtrate and filter residue, repeats to extract 2-3 times, and merge obtained filtrate is filtered；
(4) separate: the filtrate that step (3) is obtained separates by macroreticular resin, takes unadsorbed position, film filtering retention
The isolate of 25kD molecular size range, concentration, spray drying obtain wolfberry fruit extract.
Preferably, in step (1), the fructus lycii is new fresh fructus lycii；The preprocess method of the fructus lycii be include will be fresh
Fructus lycii impregnates 5-10h, multiple gentle agitation in soaking process in the water that joined 1% starch；The water containing starch is removed, is used
Clear water rinses new fresh fructus lycii 2-3 times；For several times with the blanching of boiling water interval, each 3-5s.
Preferably, in step (1), the fructus lycii is inoculated with fermentation Chinese wolfberry fruit liquid according to mass ratio 1:15-20.
Preferably, in step (1), the fermentation Chinese wolfberry fruit liquid contain 2% saccharomyces cerevisiae, 1.2% lactobacillus plantarum with
And 0.9% Lactobacillus rhamnosus.
Further, the present invention also provides a kind of preparation methods of fructus lycii Radix Astragali strengthen immunity health food, including with
Lower specific steps:
(1) Astragalus Root P.E, wolfberry fruit extract, spirulina freeze-dried powder, filler, lubricant and essence are sufficiently stirred
Mix to obtain mixture；
(2) the mixture 2min for using intensity to obtain for the electron beam irradiating step (1) of 10kGy, continues to irradiate after stirring
2min, 2-3 times repeatedly；
(3) then by step (2) sterilizing after mixture using conventional preparation method be prepared into tablet, pulvis, granule,
One of capsule or effervescent tablet.
Compared with prior art, the present invention has the advantage that
(1) present invention is fermented before extracting to fructus lycii, can be effectively reduced reduced sugar and total sugar content, is made total
Flavones and polysaccharides are purified and are improved, and macro-nutrients original in fructus lycii are resolved into small point easily absorbed
Sub- substance, and the nutritive value of fructus lycii is increased in the case where original nutriment does not lose, and well solve
The low problem of Chinese-wolfberry nutritive ingredient human body utilization rate.
(2) present invention selects to be fermented, extracted as raw material using new fresh fructus lycii, compared to solarization fructus lycii, fresh Chinese holly
Nutritional ingredient more horn of plenty in Qi, active ingredient loss is less, is more suitable as extraction material.
(3) during astragalus extraction, the present invention is destroyed in fresh astragalus root stalk cell using low temperature liquid nitrogen crushing technology
Crystal structure, and make cell membrane and cell wall damage, and heating swelling is combined to promote the release of Radix Astragali cell Dissolve things inside, have
The intracellular organic matter macromolecular of Radix Astragali is adequately decomposed conducive to bacterial strain in fermentation process, is also beneficial to subsequent ultrasonic process
Extraction efficiency is higher.
(4) present invention ferments to fresh Radix Astragali using the mixed bacteria that Bifidobacterium and saccharomyces cerevisiae form, not only
Astragalus polyose can be made sufficiently to dissociate, improve the yield of astragalus polyose, additionally it is possible to improved by the degradation of other organic impurities yellow
The purity of astragalus polysaccharides, and extract mouthfeel can be improved, additionally it is possible to make Astragalus Root P.E be easier to be absorbed by the body.
(5) present invention uses Tween-80 as nonionic surfactant during astragalus extraction, can be on surface
Interfacial Adsorption polysaccharide or in the solution formed molecular aggregate and change the dissolubility of astragalus polyose in aqueous solution, improve it is more
The extraction efficiency of sugar.
(6) present invention is also added with spirulina freeze-dried powder, rich in spirulina freeze-dried powder and easily by human consumption
The protein of absorption contains, and also contains a large amount of ferro element, gamma-Linolenic acid and spirulina polysaccharide, and spirulina polysaccharide has anti-spoke
It penetrates damage and improves side reaction caused by Radiotherapy chemotherapy and act on, and it is complementary with wolfberry fruit extract, Astragalus Root P.E to carry out compounding, it is logical
Cross the synergistic effect of three, can nourishing Yin and keeping spirit, activating microcirculation and removing stasis medicinal, improve the immunity of human body significantly.
In conclusion fructus lycii astragalus health-care food prepared by the present invention is full of nutrition, it is rich in polysaccharides and astragalus polyose,
The immunity of human body can be enhanced well.
Specific embodiment
The present invention will be further described in detail with reference to the specific embodiments.
Embodiment 1
A kind of preparation method of Astragalus Root P.E, specifically includes the following steps:
(1) it pre-processes: will be crushed after fresh Radix Astragali rhizome washing, removal impurity through low temperature liquid nitrogen, be rapidly added 5-8 times
The water of quality impregnates 2-3h under 55-60 DEG C of water bath condition.
(2) ferment: into Radix Astragali, inoculating compound bacterium agent ferments.Concentration of the composite bacteria agent in astragalus root fermentation liquor
For 0.1-0.2%, the composite bacteria agent is mixed by Bifidobacterium and saccharomyces cerevisiae according to 2:1 weight ratio；35-40 DEG C,
It is carried out anaerobic fermentation 2-3 days under the conditions of pH 5.
(3) ultrasonic extraction: being added 3-5 times of volume of water in the fermentation liquid obtained to step (2) and stir and evenly mix, and is then added poly-
Sorb ester -80 simultaneously makes its (referring to Tween-80) final concentration of 0.3-0.5%, then under 45-55 DEG C of water bath condition at ultrasound
1.5-2h is managed, suction filtration obtains filtrate and filter residue, and the water of 3-5 times of weight of filter residue is added, and repeats to extract 2-3 times, and suction filtration is obtained
Filtrate merge.
(4) separate: the filtrate that step (3) are merged separates by macroreticular resin, takes unadsorbed position, film filtering retention
The isolate of 150kD molecular size range, concentration, spray drying obtain Astragalus Root P.E.
Comparative example 1
A kind of preparation method of Astragalus Root P.E, specifically includes the following steps:
(1) ferment: into Radix Astragali, inoculating compound bacterium agent ferments.Concentration of the composite bacteria agent in astragalus root fermentation liquor
For 0.1-0.2%, the composite bacteria agent is mixed by Bifidobacterium and saccharomyces cerevisiae according to 1:1 weight ratio；35-40 DEG C,
It is carried out anaerobic fermentation 2-3 days under the conditions of pH 5.
(2) ultrasonic extraction: being added 3-5 times of volume of water in the fermentation liquid obtained to step (1) and stir and evenly mix, and is then added poly-
Sorb ester -80 simultaneously makes its final concentration of 0.3-0.5%, is then ultrasonically treated 1.5-2h under 45-55 DEG C of water bath condition, filters
To filtrate and filter residue, the water of 3-5 times of weight of filter residue is added, repeats to extract 2-3 times, and merge obtained filtrate is filtered.
(3) separate: the filtrate that step (2) are merged separates by macroreticular resin, takes unadsorbed position, film filtering retention
The isolate of 150kD molecular size range, concentration, spray drying obtain Astragalus Root P.E.
Comparative example 2
A kind of preparation method of Astragalus Root P.E, specifically includes the following steps:
(1) it pre-processes: will be crushed after fresh Radix Astragali rhizome washing, removal impurity through low temperature liquid nitrogen, be rapidly added 5-8 times
The water of quality impregnates 2-3h under 55-60 DEG C of water bath condition.
(2) ultrasonic extraction: being added 3-5 times of volume of water in the fermentation liquid obtained to step (1) and stir and evenly mix, and is then added poly-
Sorb ester -80 simultaneously makes its final concentration of 0.3-0.5%, is then ultrasonically treated 1.5-2h under 45-55 DEG C of water bath condition, filters
To filtrate and filter residue, the water of 3-5 times of weight of filter residue is added, repeats to extract 2-3 times, and merge obtained filtrate is filtered.
(3) separate: the filtrate that step (4) are merged separates by macroreticular resin, takes unadsorbed position, film filtering retention
The isolate of 150kD molecular size range, concentration, spray drying obtain Astragalus Root P.E.
Comparative example 3
A kind of preparation method of Astragalus Root P.E, specifically includes the following steps:
(1) it pre-processes: will be crushed after fresh Radix Astragali rhizome washing, removal impurity through low temperature liquid nitrogen, be rapidly added 5-8 times
The water of quality impregnates 2-3h under 55-60 DEG C of water bath condition.
(2) ferment: into Radix Astragali, inoculating compound bacterium agent ferments.Concentration of the composite bacteria agent in astragalus root fermentation liquor
For 0.1-0.2%, the composite bacteria agent is mixed by Bifidobacterium and saccharomyces cerevisiae according to 1:1 weight ratio；35-40 DEG C,
It is carried out anaerobic fermentation 2-3 days under the conditions of pH 5.
(3) ultrasonic extraction: 3-5 times of volume of water is added in the fermentation liquid obtained to step (2) and stirs and evenly mixs, in 45-55 DEG C
1.5-2h is ultrasonically treated under water bath condition, suction filtration obtains filtrate and filter residue, and the water of 3-5 times of weight of filter residue is added, and repeats to extract 2-3
It is secondary, and merged obtained filtrate is filtered.
(4) separate: the filtrate that step (3) are merged separates by macroreticular resin, takes unadsorbed position, film filtering retention
The isolate of 150kD molecular size range, concentration, spray drying obtain Astragalus Root P.E.
Measure astragalus polyose recovery rate and astragalus polyose containing in Astragalus Root P.E of embodiment 1, comparative example 1,2,3
Amount, the results are shown in Table 1.
The astragalus polyose recovery rate and astragalus polyose content that 1 Different Extraction Method of table obtains
| Embodiment 1 | Comparative example 1 | Comparative example 2 | Comparative example 3 | |
| Astragalus polyose recovery rate (%) | 25.17±2.36 | 19.78±1.96 | 16.44±1.68 | 20.22±3.01 |
| Astragalus polyose content (%) | 51.39±5.21 | 45.67±4.39 | 29.75±3.97 | 39.47±5.21 |
As shown in Table 1, the recovery rate of astragalus polyose is greater than 25%, and the Astragalus Root P.E obtained by means of the present invention
In astragalus polyose content be greater than 50%.Astragalus polyose is extracted using fermentation method of the present invention, can not only increase Radix Astragali in product
The content of polysaccharide, and because of fermentation process, the macromolecular in Radix Astragali is decomposed, moreover it is possible to improve extract mouthfeel.
Embodiment 2
A kind of preparation method of wolfberry fruit extract, specifically includes the following steps:
(1) it ferments: new fresh fructus lycii being impregnated into 5-10h in the water that joined 1% starch, is repeatedly slightly stirred in soaking process
It mixes；The water containing starch is removed, is rinsed new fresh fructus lycii 2-3 times with clear water；For several times with the blanching of boiling water interval, each 3-5s.Then
Inoculation fermentation Chinese wolfberry fruit liquid is carried out according to mass ratio 1:15-20, is fermented 3-5 days at a temperature of 28-32 DEG C after mixing.It is described
Fermentation Chinese wolfberry fruit liquid contain 2% saccharomyces cerevisiae, 1.2% lactobacillus plantarum and 0.9% Lactobacillus rhamnosus.
(2) it sterilizes: the fructus lycii after fermentation is sterilized.
(3) extract: to after sterilizing fructus lycii be added 6-8 times of quality water, impregnate 5-8h after under 45-55 DEG C of water bath condition
It is ultrasonically treated 1.5-2h, suction filtration obtains filtrate and filter residue, repeats to extract 2-3 times, and merge obtained filtrate is filtered.
(4) separate: the filtrate that step (3) is obtained separates by macroreticular resin, takes unadsorbed position, film filtering retention
The isolate of 25kD molecular size range, concentration, spray drying obtain wolfberry fruit extract.
In the wolfberry fruit extract for extracting preparation after the method for new fresh fructus lycii through this embodiment is fermented, content of reducing sugar
Compared with from new fresh fructus lycii, the not fermented wolfberry fruit extract for directly extracting preparation, content of reducing sugar reduce by 65% or more, and fructus lycii is total
Sugared content reduces by 50% or more, and content remains unchanged in polysaccharides fermentation process, and flavones content significantly increases.By the present embodiment
Method fermentation preparation wolfberry fruit extract in, content of reducing sugar reduce, general flavone and polysaccharides are purified and are improved.
Embodiment 3
A kind of fructus lycii Radix Astragali strengthen immunity health food, each component including following parts by weight:
42 parts of wolfberry fruit extract, the spirulina freeze-dried powder 9 of 27 parts of Astragalus Root P.E, the preparation of embodiment 2 prepared by embodiment 1
Part, 1 part of essence, 3 parts of starch, 1 part of microcrystalline cellulose, 1 part of xylitol, 1 part of magnesium stearate, 2 parts of talcum powder.
The present invention also provides a kind of preparation methods of fructus lycii Radix Astragali strengthen immunity health food, including walk in detail below
It is rapid:
(1) by load weighted Astragalus Root P.E, wolfberry fruit extract, spirulina freeze-dried powder, essence, starch, microcrystalline cellulose,
Xylitol, magnesium stearate, talcum powder carry out that mixture is sufficiently stirred to obtain；
(2) the mixture 2min for using intensity to obtain for the electron beam irradiating step (1) of 10kGy, continues to irradiate after stirring
2min, 3 times repeatedly；
(3) then by step (2) sterilizing after mixture using conventional preparation method be prepared into tablet, pulvis, granule,
One of capsule or effervescent tablet.
Embodiment 4
A kind of fructus lycii Radix Astragali strengthen immunity health food, each component including following parts by weight:
50 parts of wolfberry fruit extract, the spirulina freeze-dried powder of 32 parts of Astragalus Root P.E, the preparation of embodiment 2 prepared by embodiment 1
13 parts, 5 parts of starch, 3 parts of dextrin, 1 part of honey element, 1 part of magnesium stearate, 3 parts of talcum powder, 1 part of sodium benzoate, 2 parts of essence.
The present invention also provides a kind of preparation methods of fructus lycii Radix Astragali strengthen immunity health food, including walk in detail below
It is rapid:
It (1) will be by load weighted Astragalus Root P.E, wolfberry fruit extract, spirulina freeze-dried powder, starch, dextrin, honey element, hard
Mixture is sufficiently stirred to obtain in fatty acid magnesium, talcum powder, sodium benzoate；
(2) the mixture 2min for using intensity to obtain for the electron beam irradiating step (1) of 10kGy, continues to irradiate after stirring
2min, 2 times repeatedly；
(3) then by step (2) sterilizing after mixture using conventional preparation method be prepared into tablet, pulvis, granule,
One of capsule or effervescent tablet.
The foregoing is merely the preferred embodiments of invention, are not intended to limit the invention, all in spirit of the invention
Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of fructus lycii Radix Astragali strengthen immunity health food, which is characterized in that each component including following parts by weight:
27-32 parts of Astragalus Root P.E, 42-50 parts of wolfberry fruit extract, 9-13 parts of spirulina freeze-dried powder, 5-9 parts of filler, lubricant
3-5 parts, 1-2 parts of essence.
2. fructus lycii Radix Astragali strengthen immunity health food according to claim 1, it is characterised in that: the filler is that can be selected from
One or more of starch, dextrin, Icing Sugar, honey element, mannitol, xylitol, microcrystalline cellulose.
3. fructus lycii Radix Astragali strengthen immunity health food according to claim 1, it is characterised in that: the lubricant is stearic acid
One or more of magnesium, talcum powder, sodium benzoate.
4. fructus lycii Radix Astragali strengthen immunity health food according to claim 1, it is characterised in that: the system of the Astragalus Root P.E
Preparation Method, specifically includes the following steps:
(1) it pre-processes: will be crushed after fresh Radix Astragali rhizome washing, removal impurity through low temperature liquid nitrogen, be rapidly added 5-8 times of quality
Water impregnate 2-3h under 55-60 DEG C of water bath condition；
(2) ferment: into Radix Astragali, inoculating compound bacterium agent ferments；
(3) ultrasonic extraction: 3-5 times of volume of water is added in the fermentation liquid obtained to step (2) and stirs and evenly mixs, poly- sorb is then added
Ester -80 simultaneously makes its final concentration of 0.3-0.5%, and 1.5-2h is then ultrasonically treated under 45-55 DEG C of water bath condition, is filtered
The water of 3-5 times of weight of filter residue is added in liquid and filter residue, repeats to extract 2-3 times, and merge obtained filtrate is filtered；
(4) separate: the filtrate that step (3) are merged separates by macroreticular resin, takes unadsorbed position, film filtering retention
The isolate of 150kD molecular size range, concentration, spray drying obtain Astragalus Root P.E.
5. fructus lycii Radix Astragali strengthen immunity health food according to claim 4, it is characterised in that: described compound in step (2)
Concentration of the microbial inoculum in astragalus root fermentation liquor is 0.1-0.2%, and the composite bacteria agent is by Bifidobacterium and saccharomyces cerevisiae according to 2:1 weight
Amount ratio mixes；It is carried out anaerobic fermentation 2-3 days under the conditions of 35-40 DEG C, 5 pH.
6. fructus lycii Radix Astragali strengthen immunity health food according to claim 1, it is characterised in that: the system of the wolfberry fruit extract
Preparation Method, specifically includes the following steps:
(1) it ferments: being inoculated with fermentation Chinese wolfberry fruit liquid after fructus lycii is pre-processed, ferment at a temperature of 28-32 DEG C 3-5 after mixing
It；
(2) it sterilizes: the fructus lycii after fermentation is sterilized；
(3) it extracts: ultrasonic under 45-55 DEG C of water bath condition after immersion 5-8h to the water of the fructus lycii 6-8 times of quality of addition after sterilizing
1.5-2h is handled, suction filtration obtains filtrate and filter residue, repeats to extract 2-3 times, and merge obtained filtrate is filtered；
(4) separate: the filtrate that step (3) is obtained separates by macroreticular resin, takes unadsorbed position, film filtering retention 25kD
The isolate of molecular size range, concentration, spray drying obtain wolfberry fruit extract.
7. fructus lycii Radix Astragali strengthen immunity health food according to claim 6, it is characterised in that: in step (1), the fructus lycii
For new fresh fructus lycii；The preprocess method of the fructus lycii be include that new fresh fructus lycii is impregnated into 5- in the water that joined 1% starch
10h, multiple gentle agitation in soaking process；The water containing starch is removed, is rinsed new fresh fructus lycii 2-3 times with clear water；With between boiling water
Blanching have a rest for several times, each 3-5s.
8. fructus lycii Radix Astragali strengthen immunity health food according to claim 6, it is characterised in that: in step (1), the fructus lycii
It is inoculated with fermentation Chinese wolfberry fruit liquid according to mass ratio 1:15-20.
9. fructus lycii Radix Astragali strengthen immunity health food according to claim 8, it is characterised in that: in step (1), the fructus lycii
Fermentation liquid contain 2% saccharomyces cerevisiae, 1.2% lactobacillus plantarum and 0.9% Lactobacillus rhamnosus.
10. the preparation method of any one of -9 fructus lycii Radix Astragali strengthen immunity health food, feature exist according to claim 1
In, comprising the following specific steps
(1) Astragalus Root P.E, wolfberry fruit extract, spirulina freeze-dried powder, filler, lubricant and essence be sufficiently stirred
Mixture；
(2) the mixture 2min for using intensity to obtain for the electron beam irradiating step (1) of 10kGy continues to irradiate 2min after stirring,
2-3 times repeatedly；
(3) mixture after step (2) sterilizing is then prepared into tablet, pulvis, granule, capsule using conventional preparation method
One of agent or effervescent tablet.
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| CN115644447A (en) * | 2022-11-10 | 2023-01-31 | 贵州省分析测试研究院 | Non-total nutrient special medical food thickening component and preparation method thereof |
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