CN109260291A - A kind of washout anaesthetic for treating psoriasis - Google Patents
A kind of washout anaesthetic for treating psoriasis Download PDFInfo
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- CN109260291A CN109260291A CN201811408130.3A CN201811408130A CN109260291A CN 109260291 A CN109260291 A CN 109260291A CN 201811408130 A CN201811408130 A CN 201811408130A CN 109260291 A CN109260291 A CN 109260291A
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- anaesthetic
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- washout
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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Abstract
The invention discloses a kind of washout anaesthetic for treating psoriasis, the external use liquid made of the anaesthetic raw material of following weight parts: 20~40 parts of Fructus Aurantii, 20~40 parts of sophora flower, 20~40 parts of schizonepeta, 20~40 parts of folium artemisiae argyi.Formula of the invention is to form on the basis of anaesthetic folk remedy by a large amount of experiment screening compatibility, significant for the therapeutic effect of psoriasis, and high degree reduces the generation rate and drug resistance of drug resistance, and uneasy to recur.
Description
Technical field
The present invention relates to field of medicaments, and in particular to a kind of washout anaesthetic for treating psoriasis, the invention further relates to the illiteracies
The preparation method of medicine.
Background technique
Psoriasis is commonly called as psoriasis, is a kind of chronic inflammatory skin, and the course of disease is longer, easy recurrent exerbation, persistent ailment, with me
State's northern area person between twenty and fifty's frequently-occurring disease, have certain heredity, without infectiousness the features such as.Traditional Mongolian medicine is recognized, and extravesated blood and yellow water are these
The internal cause of disease.Diet is irregular, drink beyond one's capacity, hang up one's hat it is moist filthily, direct stimulation, catch cold, have a sleepless night, overwork,
Contact allergy source, hypoimmunity, inferior health, the diseases effect such as upper sense and influenza cause blood and Huang under the effect of the outer rims such as wound
Water is contained caused by skin partially.Any area skin is betided, four limbs outside, head, back and chest are common, and the state of an illness aggravates in winter,
Summer has set in and alleviate.
At present doctor trained in Western medicine frequently with vitamins, antibiotics, immunomodulator or agonist, act on the medicine of nervous system
The externally applied drugs such as the medicines for oral administration such as object or hormone, cutin forming agent, cellulotoxic preparation, and the often irradiation of cooperation ultraviolet light, photochemical method
Equal this disease of complex treatments.But clinical practice proves, said medicine and therapy can often generate toxic side effect, and there are many contraindications.
And Mongolian medicine's anaesthetic has more than 2700 years long history, traditional Mongolian medicine's anaesthetic but has the treatment of psoriasis
Original method and magical effect.The productions activities such as the Mongols is national and its ancestors' long campaigns are nomadic, hunts, living condition
It is arduouser, thus have accumulated Couple herbs abundant, form treatment a variety of methods of psoriasis it is simple, it is quickly effective, at low cost,
The Prescription of Mongolian Medicine that treatment time is short, patient suffering is few, and with toxic side effect, few, resource environment destroys less anaesthetic, medication facilitates
Etc. excellent feature.
Summary of the invention
A kind of washout for treatment psoriasis few, easy to use and curative for effect that the object of the present invention is to provide toxic side effects
Anaesthetic.
In order to solve the above technical problems, the technical solution adopted in the present invention is as follows:
A kind of washout anaesthetic for treating psoriasis, anaesthetic external use liquid made of the anaesthetic raw material of following weight parts:
20~40 parts of Fructus Aurantii
20~40 parts of sophora flower
20~40 parts of schizonepeta
20~40 parts of folium artemisiae argyi.
Preferably, above-mentioned anaesthetic external use liquid made of the anaesthetic raw material of following weight parts:
30 parts of Fructus Aurantii
30 parts of sophora flower
30 parts of schizonepeta
30 parts of folium artemisiae argyi.
A kind of preparation method for the washout anaesthetic for treating psoriasis of the present invention, comprising the following steps:
(1) raw material mixes
It weighs the fine powder facing-up of Fructus Aurantii, sophora flower, schizonepeta, folium artemisiae argyi respectively by formula ratio, is sieved, mix；
(2) it decocts
The water that 40 times of weight of raw material are added is decocted, and boiling water decocts 20 minutes.
External use liquid of the invention when in use, twice daily, 30 minutes foam washing diseased region skin every time.
The present invention is with Mongolian medicine's Overall View, fever and chills are theoretical, Mongolian medicine's disease invade six theories (dissipate in skin, be distributed in flesh, row in
Arteries and veins, sink into bone, volt in it is dirty, fall within internal organs) etc. basic theories be guiding theory, with anaesthetic nature and flavor, the efficacy of a drug, effect, efficiency, drug
Based on the basic theories of taste, follow strictly Prescription of Mongolian Medicine rule of compound concrete, principle composition side, obtain at low cost, treatment time is short,
The few Prescription of Mongolian Medicine of patient suffering.
Formula of the invention is to form on the basis of anaesthetic folk remedy by a large amount of experiment screening compatibility, for
The therapeutic effect of psoriasis is significant, and high degree reduces the generation rate and drug resistance of drug resistance, and uneasy to recur；Without hormone, nothing
Side effect.
Specific embodiment
Of the invention for ease of understanding, it is as follows that the present invention enumerates embodiment.Those skilled in the art are it will be clearly understood that the implementation
Example is used only for helping to understand the present invention, should not be regarded as a specific limitation of the invention.
Unless specific instructions, various raw materials of the invention can be by being commercially available；Or the routine side according to this field
Method is prepared.Unless otherwise defined or described herein, all professional and scientific terms and art technology used herein are ripe
It is identical to practice meaning known to personnel.Furthermore any method similar to or equal to what is recorded and material all can be applied to this
In inventive method.Unless otherwise stated, all professional and scientific terms and those skilled in the art used herein
Known meaning is identical.
Embodiment 1
The washout anaesthetic of the treatment psoriasis of the present embodiment, the external use liquid made of the anaesthetic raw material of following weight parts:
30 grams of Fructus Aurantii, 30 grams of sophora flower, 30 grams of schizonepeta, 30 grams of folium artemisiae argyi.
Preparation method the following steps are included:
(1) raw material mixes
It weighs the fine powder facing-up of Fructus Aurantii, sophora flower, schizonepeta, folium artemisiae argyi respectively by formula ratio, is sieved, mix；
(2) it decocts
Raw material 5000ml water is added to be decocted, boiling water decocts after twenty minutes, obtains the 3000ml present invention and treats psoriasis
Washout anaesthetic.
The washout anaesthetic of the present embodiment when in use, twice daily, 30 minutes foam washing diseased region skin every time, two
Week is as a treatment course.In addition, the washout anaesthetic of the present embodiment is when in use, pungent, irritable food is avoided；To skin allergy, person is careful
With.Direct stimulation is avoided, catches cold, have a sleepless night, overwork.
Clinical research situation is as follows:
1, diagnostic criteria is according to " Surgery of Chinese Medicine ".Clinical manifestation is fash emergence, is quickly grown, mostly presentation drop
Shape, color is scarlet, and the scales of skin that peel off increases, acute pruritus, and that grabs has sieve-like blutpunkte；With mouth parched and tongue scorched, have sore throat, dysphoria,
It is hard and dry, dark urine；Red tongue body moss thin yellow, wiry and rolling pulse or number screen 200 altogether.
2, treatment group: 100, male 44, female 56；
Control group: 100, male 49, female 51.
The comparing differences such as two groups of ages, gender, the course of disease, state of an illness are not statistically significant (P > 0.05), are comparable.
3, treatment group: using the washout anaesthetic of embodiment 1, twice daily, 30 minutes foam washing diseased region skin every time, two
Week is as a treatment course.
Control group: Xiaoyin capsule 5~7 are used, 3 times a day, two weeks as a treatment course.
4, clinical therapeutic efficacy:
Criterion of therapeutical effect: it is evaluated and is treated according to international psoriatic lesion area severity index (PASI) standards of grading
Effect.
Recovery from illness: PASI integral decline >=90%, skin lesion all subside or only remain a small number of drop damages, and itch disappears；
Effective: decline 60%~89%, 60% or more skin lesion recession occasionally have itch；
Effective: decline 25%~9%, 30% or more skin lesion recession still have itch；
Invalid: integral decline < 25%, skin lesion subside 30% or less or without improvement, hence it is evident that itch, it is difficult to endure；
Recovery from illness, effective, effectively total calculating is efficient.
5, the treatment results after two courses for the treatment of are as follows:
The pretherapy and post-treatment PASI of table 1 scoring is compared
2 two groups of patients of table treat therapeutic effect and compare
| Group | Recovery from illness | It is effective | Effectively | In vain | Efficient % |
| Treatment group | 70 | 28 | 98 | 2 | 98% |
| Control group | 22 | 35 | 57 | 43 | 57% |
It can be seen that from the data of above-mentioned Tables 1 and 2 using the patient using washout anaesthetic of the invention, after treatment
PASI scoring is substantially less than before treatment (P < 0.05)；Meanwhile using washout anaesthetic of the invention, efficient (recovery from illness adds effective add
Effectively) also it is significantly better than control group (P < 0.05).
Embodiment 2
The washout anaesthetic of the treatment psoriasis of the present embodiment, the external use liquid made of the anaesthetic raw material of following weight parts:
20 grams of Fructus Aurantii, 20 grams of sophora flower, 20 grams of schizonepeta, 20 grams of folium artemisiae argyi.
Preparation method is same as embodiment 1.
Embodiment 3
The washout anaesthetic of the treatment psoriasis of the present embodiment, the external use liquid made of the anaesthetic raw material of following weight parts:
40 grams of Fructus Aurantii, 40 grams of sophora flower, 40 grams of schizonepeta, 40 grams of folium artemisiae argyi.
Preparation method is same as embodiment 1.
Although the detailed description and description of the specific embodiments of the present invention are given above, it should be noted that
We can carry out various equivalent changes and modification to above embodiment according to the concept of the present invention, and generated function is made
It, should all be within protection scope of the present invention when with the spirit still covered without departing from specification.
Claims (3)
1. a kind of washout anaesthetic for treating psoriasis, which is characterized in that the anaesthetic is made of the anaesthetic raw material of following weight parts
External use liquid:
20~40 parts of Fructus Aurantii
20~40 parts of sophora flower
20~40 parts of schizonepeta
20~40 parts of folium artemisiae argyi.
2. a kind of washout anaesthetic for treating psoriasis described in accordance with the claim 1, which is characterized in that the anaesthetic is by following heavy
Measure external use liquid made of the anaesthetic raw material of part:
30 parts of Fructus Aurantii
30 parts of sophora flower
30 parts of schizonepeta
30 parts of folium artemisiae argyi.
3. a kind of preparation method of washout anaesthetic for treating psoriasis described in accordance with the claim 1, which is characterized in that including with
Lower step:
(1) raw material mixes
It weighs the fine powder facing-up of Fructus Aurantii, sophora flower, schizonepeta, folium artemisiae argyi respectively by formula ratio, is sieved, mix；
(2) it decocts
The water that 40 times of weight of raw material are added is decocted, and boiling water decocts 20 minutes.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811408130.3A CN109260291A (en) | 2018-11-23 | 2018-11-23 | A kind of washout anaesthetic for treating psoriasis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811408130.3A CN109260291A (en) | 2018-11-23 | 2018-11-23 | A kind of washout anaesthetic for treating psoriasis |
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| Publication Number | Publication Date |
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| CN109260291A true CN109260291A (en) | 2019-01-25 |
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| CN201811408130.3A Pending CN109260291A (en) | 2018-11-23 | 2018-11-23 | A kind of washout anaesthetic for treating psoriasis |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108175838A (en) * | 2018-03-26 | 2018-06-19 | 王吉坤 | A kind of fumigation-washing medicine for treating blood-head psoriasis pustulosa |
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2018
- 2018-11-23 CN CN201811408130.3A patent/CN109260291A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108175838A (en) * | 2018-03-26 | 2018-06-19 | 王吉坤 | A kind of fumigation-washing medicine for treating blood-head psoriasis pustulosa |
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| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190125 |
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| RJ01 | Rejection of invention patent application after publication |