CN109224065A - A kind of bee peptide disinfection of Chinese drug bactericidal wet tissue - Google Patents

A kind of bee peptide disinfection of Chinese drug bactericidal wet tissue Download PDF

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Publication number
CN109224065A
CN109224065A CN201810232751.4A CN201810232751A CN109224065A CN 109224065 A CN109224065 A CN 109224065A CN 201810232751 A CN201810232751 A CN 201810232751A CN 109224065 A CN109224065 A CN 109224065A
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parts
disinfection
wet tissue
bee
bee venom
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刘静
赵巍然
赵骏腾
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention provides a kind of bee peptide disinfection of Chinese drug bactericidal wet tissue, it is prepared by following bulk drugs, it is 1-5 parts of parts by weight honeybee bee venom, 1-5 parts of wasp bee venom, 20-30 parts of honeysuckle, 10-20 parts of lemon juice, 10-30 parts of wormwood, 10-30 parts of Chinese prickly ash, 1-5 parts of glycerol, 20-30 parts of asparagus juice, 20-30 parts of lilac, the wet tissue fragrant taste of inventive formulation preparation, it is small to the irritation of skin, sterilizing can promote the metabolism of skin simultaneously, it delays senescence, be conducive to dispel the wrinkle of skin surface, traditional non-woven fabrics is replaced using bamboo charcoal fiber cloth, bacteriostasis antibiosis, with strong adsorptivity, it can the impurity such as grease in deep clean pore, it is good to clean effect spy, and process of preparing is simple, it is high-efficient.

Description

A kind of bee peptide disinfection of Chinese drug bactericidal wet tissue
Technical field
The invention belongs to Chinese medicine nursing technical field more particularly to a kind of bee peptide disinfection of Chinese drug bactericidal wet tissues.
Background technique
With the raising of people 's material life level, wet tissue, which has become, commonly cleans necessity in people's daily life. It cleans halfway drawback instead of original paper handkerchief, adds watersoluble cleaning ingredient in ingredient, can not only remove dust Spot more effectively eliminates grease, is the product of people's travelling, the indispensability gone on business.
The wet tissue type sold currently on the market is varied, can be roughly divided into two types: one kind is that itself is disappeared Poison, but other articles cannot be sterilized, ingredient of the inside containing skin care can only do skin wet maintenance.It is another kind of be not only this Body is sterilized, and the pasteurization towelette of disinfection can also be played to other article, can be used as disappearing for skin abrasion, scuffing etc. Poison or sterilization.As it can be seen that outgoing be preferably selected the pasteurization towelette with sterilizing function.
But wet tissue pasteurization towelette currently on the market, penetrating odor is big, using common non-woven fabrics facial mask and skin Affinity is bad, and pore grease, impurity foreign matter residual fabric also will cause pruitus allergy on the skin, and to skin nursing Effect.
Therefore, a kind of bee peptide disinfection of Chinese drug bactericidal wet tissue is invented to be very necessary.
Summary of the invention
Existing defect in view of the above technical problems, the present invention provide a kind of bee peptide disinfection of Chinese drug bactericidal wet tissue.
A kind of bee peptide disinfection of Chinese drug bactericidal wet tissue, is prepared by following bulk drugs, is parts by weight:
1-5 part of honeybee bee venom, 1-5 part of wasp bee venom
10-20 parts of lemon juice of 20-30 portions of honeysuckle
10-30 parts of Chinese prickly ash of 10-30 portions of wormwood
20-30 parts of asparagus juice of 1-5 portions of glycerol
20-30 parts of lilac.
Preferably, a kind of bee peptide disinfection of Chinese drug bactericidal wet tissue, it is configured to by the raw material of following weight parts:
5-10 parts of honeybee bee venom, 5-10 parts of wasp bee venom,
30-50 parts of honeysuckle, 5-10 parts of lemon juice,
5-10 parts of wormwood, 5-10 parts of Chinese prickly ash,
1-5 parts of glycerol, 10-20 parts of asparagus juice
30-60 parts of lilac.
A method of bee peptide disinfection of Chinese drug bactericidal wet tissue being prepared, preparation step is as follows:
Step 1: wormwood, Chinese prickly ash, lilac being cleaned and cleaned, and are added in pottery according to aforementioned proportion and clear water is added to not having Whole medicinal raw materials are crossed, amount of water is 12-15 times of raw material gross weight, is impregnated 30-50 minutes, then heating is cooked by slow fire 50- 80min filters through 200-240 mesh stainless steel filter screen, obtains filtrate；
Step 2: being placed on honeysuckle, lilac in pulverizer and crush, and resulting pulverized particles are added in pure water, It is purified using ultrasonic wave equipment for purifying, purification temperature is 30-50C °, time 50-80min, the ethyl alcohol for being 70% with concentration Obtained mixed liquor is filtered through 200-240 mesh stainless steel filter screen, and filtrate is placed in distillation ware and is distilled by elution, is obtained Aqueous solution containing honeysuckle, cloves flower extract；
Step 3: it after lemon peeling cleaning and sterilizing sterilization, through grinding treatment, is added with 5-10 times of lemon weight of pure water In lemon grinding bodies, after impregnating 30-50min, liquid is obtained using 200-300 mesh filter screen filtration；
Step 4: resulting liquid mixing is prepared by above-mentioned, and honeybee bee venom, wasp bee venom, glycerol is added and is uniformly mixed Afterwards, base fluid is obtained, it is spare；
Step 5: the fiber after disinfection is arranged in mixed liquor obtained by step 4, is impregnated 30-40min, is sealed after sterilizing Dress packet.
Preferably, the fiber cloth specifically uses bamboo charcoal fiber cloth.
Preferably, the frequency of the ultrasonic wave equipment for purifying purification is 20-30KHz.
Melittin have it is anti-inflammatory, adjust immunization, can directly inhibit inflammation, swelling, one adrenal system of Stimulation of Pituitary Gland, Promote the release of cortin, anti-inflammatory adjustment immune function can also directly increase blood plasma cortisol；Inhibit leukocytoplania, limit The local reaction of inflammation processed.Melittin is capable of the development of Gram-negative and Gram-positive pathogens microorganism always, and can be right The anti-staphylococcus aureus that drug resistance is known as to mould.Melittin can increase capillary permeability, improve microcirculation, promote Epidermal cell metabolism accelerates the old and new's Skin Cell to substitute, makes turgor, high resilience.It can also nutrition reparation flesh battalion Undesirable cell is supported, Skin Cell is made to rejuvenate again.Melittin also has the effects that apparent anti-oxidant, anti-ultraviolet radiation, Scytitis can be eliminated, inhibit swelling, delaying skin aging.
Cloves one can neutralize wormwood, pepper water penetrating odor, and another aspect lilac aromatic stomachic can be relieved abdomen Portion's inflatable increases gastric secretion, enhances digestion power, mitigates nausea and vomiting, liquid is to staphylococcus, streptococcus, large intestine bar Bacterium, typhoid bacillus, Pseudomonas aeruginosa etc. have inhibiting effect；
Honeysuckle, nature and flavor: it is sweet, it trembles with fear.Channel tropism: return lung, the heart, stomach meridian.Effect: clearing heat and detoxicating, wind-heat dissipating.The major functions: being used for carbuncle swells Furunculosis, sore throat, erysipelas, toxic-heat and blood stasis, wind-heat cold, warm disease and fever；
Lemon is rich in vitamin C, and the effect played to human body has antibacterial anti-inflammatory, enhancing human immunity like natural antibiotics The multiple efficacies such as power have very strong antioxidation, the metabolism, anti-aging and inhibition pigmentation to skin is promoted Etc. largely effective；
Chinese prickly ash has the effect of fragrant stomach invigorating, warming spleen and stomach for dispelling cold, damp dispelling and pain relieving, desinsection removing toxic substances, antipruritic solution raw meat；
Folium artemisiae argyi has antibacterial and antivirus action；It relievings asthma, antibechic and phlegm-dispelling functions, hemostasis and blood coagulation resisting function, calm and anti-mistake Quick effect can control wet sore scabies, removing dampness to stop itchin；
Bamboo charcoal fiber bacteriostasis antibiosis, superpower adsorption capacity: bamboo Charcoal Adsorption ability is 5 times of charcoal or more, and enough removal pores are dirty Dirt boosts metabolism, and to reach Peppermint Extract, it is good to clean effect spy for deep layer purification for export.
Compared with prior art, the invention has the following beneficial effects:
1, the wet tissue fragrant taste of inventive formulation preparation, small to the irritation of skin, sterilizing can promote skin simultaneously Metabolism delays senescence, and is conducive to the wrinkle that can dispel skin surface.
2, the present invention using bamboo charcoal fiber cloth replace traditional non-woven fabrics, bacteriostasis antibiosis, have strong adsorptivity, can depth it is clear It is good to clean effect spy for the impurity such as the grease in clean pore.
3, the melittin that the present invention uses can increase capillary permeability, improve microcirculation, promote epidermal cell newly old Metabolism accelerates the old and new's Skin Cell to substitute, and makes turgor, and there is apparent anti-oxidant, anti-ultraviolet radiation etc. to make for high resilience With, can eliminate scytitis, inhibit swelling, delaying skin aging.
4, honeysuckle of the present invention, lilac pulverized particles carry out ultrasonic extraction using ultrasonic wave extraction equipment, utilize ultrasound The mechanical effect that wave has, cavitation effect and fuel factor, by increasing the movement velocity of medium molecule, increasing the penetration power of medium To extract biological effective components, extraction medical fluid impurity is few, and effective component is easily isolated, purifies, and extraction process operating cost is low.
Specific embodiment
The present invention is described further below:
Embodiment:
A kind of bee peptide disinfection of Chinese drug bactericidal wet tissue, is prepared by following bulk drugs, is parts by weight:
1-5 part of honeybee bee venom, 1-5 part of wasp bee venom
10-20 parts of lemon juice of 20-30 portions of honeysuckle
10-30 parts of Chinese prickly ash of 10-30 portions of wormwood
20-30 parts of asparagus juice of 1-5 portions of glycerol
20-30 parts of lilac.
Preferably, a kind of bee peptide disinfection of Chinese drug bactericidal wet tissue, it is configured to by the raw material of following weight parts:
5-10 parts of honeybee bee venom, 5-10 parts of wasp bee venom,
30-50 parts of honeysuckle, 5-10 parts of lemon juice,
5-10 parts of wormwood, 5-10 parts of Chinese prickly ash,
1-5 parts of glycerol, 10-20 parts of asparagus juice
30-60 parts of lilac.
A method of bee peptide disinfection of Chinese drug bactericidal wet tissue being prepared, preparation step is as follows:
Step 1: wormwood, Chinese prickly ash, lilac being cleaned and cleaned, and are added in pottery according to aforementioned proportion and clear water is added to not having Whole medicinal raw materials are crossed, amount of water is 12-15 times of raw material gross weight, is impregnated 30-50 minutes, then heating is cooked by slow fire 50- 80min filters through 200-240 mesh stainless steel filter screen, obtains filtrate；
Step 2: being placed on honeysuckle, lilac in pulverizer and crush, and resulting pulverized particles are added in pure water, It is purified using ultrasonic wave equipment for purifying, purification temperature is 30-50C °, time 50-80min, the ethyl alcohol for being 70% with concentration Obtained mixed liquor is filtered through 200-240 mesh stainless steel filter screen, and filtrate is placed in distillation ware and is distilled by elution, is obtained Aqueous solution containing honeysuckle, cloves flower extract；
Step 3: it after lemon peeling cleaning and sterilizing sterilization, through grinding treatment, is added with 5-10 times of lemon weight of pure water In lemon grinding bodies, after impregnating 30-50min, liquid is obtained using 200-300 mesh filter screen filtration；
Step 4: resulting liquid mixing is prepared by above-mentioned, and honeybee bee venom, wasp bee venom, glycerol is added and is uniformly mixed Afterwards, base fluid is obtained, it is spare；
Step 5: the fiber after disinfection is arranged in mixed liquor obtained by step 4, is impregnated 30-40min, is sealed after sterilizing Dress packet.
The fiber cloth specifically uses bamboo charcoal fiber cloth.
The frequency of the ultrasonic wave equipment for purifying purification is 20-30KHz.
Using technical solutions according to the invention or those skilled in the art under the inspiration of technical solution of the present invention, Similar technical solution is designed, and reaches above-mentioned technical effect, is to fall into protection scope of the present invention.

Claims (5)

1. a kind of bee peptide disinfection of Chinese drug bactericidal wet tissue, which is characterized in that be prepared by following bulk drugs, be parts by weight:
1-5 part of honeybee bee venom, 1-5 part of wasp bee venom
10-20 parts of lemon juice of 20-30 portions of honeysuckle
10-30 parts of Chinese prickly ash of 10-30 portions of wormwood
20-30 parts of asparagus juice of 1-5 portions of glycerol
20-30 parts of lilac.
2. bee peptide disinfection of Chinese drug bactericidal wet tissue as described in claim 1, which is characterized in that it is the raw material by following weight parts It is configured to:
5-10 parts of honeybee bee venom, 5-10 parts of wasp bee venom,
30-50 parts of honeysuckle, 5-10 parts of lemon juice,
5-10 parts of wormwood, 5-10 parts of Chinese prickly ash,
1-5 parts of glycerol, 10-20 parts of asparagus juice
30-60 parts of lilac.
3. a kind of method for preparing any bee peptide disinfection of Chinese drug bactericidal wet tissue of claim 1-2, which is characterized in that preparation Steps are as follows:
Step 1: wormwood, Chinese prickly ash, lilac being cleaned and cleaned, and are added in pottery according to aforementioned proportion and clear water is added to not having Whole medicinal raw materials are crossed, amount of water is 12-15 times of raw material gross weight, is impregnated 30-50 minutes, then heating is cooked by slow fire 50- 80min filters through 200-240 mesh stainless steel filter screen, obtains filtrate；
Step 2: being placed on honeysuckle, lilac in pulverizer and crush, and resulting pulverized particles are added in pure water, It is purified using ultrasonic wave equipment for purifying, purification temperature is 30-50C °, time 50-80min, the ethyl alcohol for being 70% with concentration Obtained mixed liquor is filtered through 200-240 mesh stainless steel filter screen, and filtrate is placed in distillation ware and is distilled by elution, is obtained Aqueous solution containing honeysuckle, cloves flower extract；
Step 3: it after lemon peeling cleaning and sterilizing sterilization, through grinding treatment, is added with 5-10 times of lemon weight of pure water In lemon grinding bodies, after impregnating 30-50min, liquid is obtained using 200-300 mesh filter screen filtration；
Step 4: resulting liquid mixing is prepared by above-mentioned, and honeybee bee venom, wasp bee venom, glycerol is added and is uniformly mixed Afterwards, base fluid is obtained, it is spare；
Step 5: the fiber after disinfection is arranged in mixed liquor obtained by step 4, is impregnated 30-40min, is sealed after sterilizing Dress packet.
4. bee peptide disinfection of Chinese drug bactericidal wet tissue as claimed in claim 3, which is characterized in that the fiber cloth specifically uses bamboo charcoal Fiber cloth.
5. bee peptide disinfection of Chinese drug bactericidal wet tissue as claimed in claim 3, which is characterized in that the ultrasonic wave equipment for purifying purification Frequency be 20-30KHz.
CN201810232751.4A 2018-03-21 2018-03-21 A kind of bee peptide disinfection of Chinese drug bactericidal wet tissue Pending CN109224065A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110279846A (en) * 2019-08-08 2019-09-27 武汉易瑞生物医药有限公司 Immune activation peptide adjusts antibacterial gynecological gel
CN110548131A (en) * 2019-08-08 2019-12-10 武汉易瑞生物医药有限公司 Bacteriostatic liquid

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CN107028858A (en) * 2016-12-19 2017-08-11 哈尔滨灵草舒生物科技有限公司 A kind of lilac anti-aging shower cream and preparation method thereof
CN108042466A (en) * 2017-12-12 2018-05-18 刘宝刚 A kind of anti-inflammatory sterilization, the oral care composition of prevention and treatment dental caries

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110279846A (en) * 2019-08-08 2019-09-27 武汉易瑞生物医药有限公司 Immune activation peptide adjusts antibacterial gynecological gel
CN110548131A (en) * 2019-08-08 2019-12-10 武汉易瑞生物医药有限公司 Bacteriostatic liquid

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Application publication date: 20190118

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