CN109224004A - A kind of external use plaster and preparation method thereof for treating the proliferation of mammary gland - Google Patents
A kind of external use plaster and preparation method thereof for treating the proliferation of mammary gland Download PDFInfo
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- 210000005075 mammary gland Anatomy 0.000 title claims abstract description 19
- 230000035755 proliferation Effects 0.000 title claims abstract description 17
- 239000011505 plaster Substances 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 23
- 239000000843 powder Substances 0.000 claims abstract description 14
- 239000000919 ceramic Substances 0.000 claims abstract description 13
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 10
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 10
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 9
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 9
- 244000179560 Prunella vulgaris Species 0.000 claims abstract description 9
- 235000010674 Prunella vulgaris Nutrition 0.000 claims abstract description 9
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 9
- 239000011159 matrix material Substances 0.000 claims abstract description 6
- 241000031023 Amana edulis Species 0.000 claims abstract description 5
- 241000244987 Daiswa polyphylla Species 0.000 claims abstract description 5
- 238000004821 distillation Methods 0.000 claims abstract description 5
- 239000004745 nonwoven fabric Substances 0.000 claims abstract description 5
- 239000000758 substrate Substances 0.000 claims abstract description 5
- 241000432824 Asparagus densiflorus Species 0.000 claims abstract description 4
- 244000178320 Vaccaria pyramidata Species 0.000 claims abstract description 4
- 235000010587 Vaccaria pyramidata Nutrition 0.000 claims abstract description 4
- 240000001949 Taraxacum officinale Species 0.000 claims abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- 239000000284 extract Substances 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 239000000341 volatile oil Substances 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 108010010803 Gelatin Proteins 0.000 claims description 4
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 229920000159 gelatin Polymers 0.000 claims description 4
- 239000008273 gelatin Substances 0.000 claims description 4
- 235000019322 gelatine Nutrition 0.000 claims description 4
- 235000011852 gelatine desserts Nutrition 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 4
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 4
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 4
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 4
- 239000002893 slag Substances 0.000 claims description 4
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims description 2
- 239000008367 deionised water Substances 0.000 claims description 2
- 229910021641 deionized water Inorganic materials 0.000 claims description 2
- 239000000835 fiber Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 235000006793 Artemisia stelleriana Nutrition 0.000 claims 1
- 244000252230 Artemisia stelleriana Species 0.000 claims 1
- 244000241257 Cucumis melo Species 0.000 claims 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 claims 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 claims 1
- 235000006413 coastal sagewort Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 19
- 239000000463 material Substances 0.000 abstract description 7
- 230000008961 swelling Effects 0.000 abstract description 6
- 235000008326 Trichosanthes anguina Nutrition 0.000 abstract description 4
- 244000078912 Trichosanthes cucumerina Species 0.000 abstract description 4
- 206010020751 Hypersensitivity Diseases 0.000 abstract description 3
- 230000003213 activating effect Effects 0.000 abstract description 3
- 208000026935 allergic disease Diseases 0.000 abstract description 3
- 230000007815 allergy Effects 0.000 abstract description 3
- 235000013399 edible fruits Nutrition 0.000 abstract description 3
- 230000004089 microcirculation Effects 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 description 7
- 241000245665 Taraxacum Species 0.000 description 6
- 206010042674 Swelling Diseases 0.000 description 4
- 210000000481 breast Anatomy 0.000 description 4
- 239000006071 cream Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 238000002242 deionisation method Methods 0.000 description 2
- 206010020718 hyperplasia Diseases 0.000 description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 2
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000009514 concussion Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 210000004907 gland Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Classifications
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
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- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
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- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
- A61N2005/066—Radiation therapy using light characterised by the wavelength of light used infrared far infrared
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- General Health & Medical Sciences (AREA)
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- Pregnancy & Childbirth (AREA)
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Abstract
The present invention relates to a kind of external use plasters for treating the proliferation of mammary gland to be prepared according to a certain percentage by Snakegourd Fruit, the seed of cowherb, edible tulip, caulis bambusae in taenian, peach kernel, Paris polyphylla, dandelion, safflower, peach kernel, Prunella vulgaris, asparagus fern, rhizoma cyperi, far-infared ceramic powder, preparation method is extracted using the way of distillation, hydrophilic matrix raw material does patch substrate, is applied on non-woven fabrics and patch is made.The present invention cooperates far-infrared ray material using dispersing stagnated hepatoqi, activating microcirculation and removing stasis medicinal, clearing heat and detoxicating, swelling and pain relieving Chinese medicine as primary raw material, and allergy, viscosity is not moderate for manufactured external use plaster, is affixed on proliferation of mammary gland position, can rapid swelling and pain relieving.
Description
Technical field
The present invention relates to pharmaceutical technology more particularly to a kind of external use plasters for treating the proliferation of mammary gland.
Background technique
Hyperplasia of mammary glands stimulates body of gland to generate hypertrophy and then presses mainly due to the unbalance medication of female incretion
Compel nerve and generates distending pain.How ineffective chemistry general for cyclomastopathy or endocrine adjustment drug be at present, and cannot be straight
Up to lesion, and side effect is big.
Some galactophore pastes used at present treat the proliferation of mammary gland, but most of drug constitutes or DNA purity is inadequate,
Traditional Chinese medicine powder directly crushes cream processed, causes the drug concentration of Transdermal absorption low, while the reason of because of preparation technique, drug or medicine
Cream mount material stimulation skin, easily cause skin allergy etc., affect patient use or adhere to using.
Summary of the invention
The present invention is a kind of external application bar cloth patch and preparation method thereof for treating the proliferation of mammary gland.
In view of the deficiencies of the prior art, according to theory of traditional Chinese medical science, select have dispersing stagnated hepatoqi, activating microcirculation and removing stasis medicinal, it is clearing heat and detoxicating, disappear
Swell the Chinese medicine material reasonable formula relieved pain, and Chinese medicine mentions through essence and be added far-infrared ray material in lotion, utilizes the depth of far infrared
Layer concussion principle, collaboration effective components of Chinese medicinal can play resolving hard lump, the purpose of swelling and pain relieving；Meanwhile it being mentioned using new Chinese medicine
Taking technique and water-soluble patch host material；The compatibility of manufactured patch and skin is good, and it is big to take dose, and drug release property is good, transdermal
It absorbs well, hydrophilic matrix is non-stimulated to skin, can notice repeatedly.It is mainly used for the proliferation of mammary gland, lump in breast, pain etc.
Women population.
In order to achieve the above-mentioned object of the invention, the present invention the following technical schemes are provided:
A kind of external use plaster for treating the proliferation of mammary gland is prepared by following raw material in parts by weight: 2-3 parts of Snakegourd Fruit, Wang Buliu
3-4 parts of row, 1-2 parts of edible tulip, 1-2 parts of caulis bambusae in taenian, 3-4 parts of peach kernel, 1-3 parts of Paris polyphylla, 2-5 parts of dandelion, 1-3 parts of safflower, peach kernel
2-4 parts, 2-5 parts of Prunella vulgaris, 1-3 parts of asparagus fern, 1-3 parts of rhizoma cyperi, 0.1-10 parts of far-infared ceramic powder.
A kind of external use plaster for treating the proliferation of mammary gland of the present invention the preparation method is as follows:
Step 1: 0.1-10 parts of far-infared ceramic powders are ground it is spare, take the dandelion of above-mentioned components by weight percent, safflower, Prunella vulgaris,
8 times of amounts of fragrant additional water are impregnated 2-4 hour, are extracted with the way of distillation, and 2 times of amounts for slightly slipping that liquid is raw material are collected, to it is thick slip liquid into
Volatile oil is collected in row redistillation, spare；
Step 2: by step 1 extraction slag and distillate mix with remaining raw material, extracted 2 times with decocting method, 8 times for the first time
Amount is extracted 2 hours, and extracting solution is collected, and second of 6 times of amount is extracted 1.5 hours, is collected and is merged extracting solution twice, and filtering is concentrated into
Relative density is 0.8-1.4 medicinal extract (60 DEG C of survey)；
Step 3 does patch substrate, specially polyvinylpyrrolidone 3-6 parts, natrium adetate using hydrophilic matrix raw material
0.01-2 parts, 3--9 parts of Sodium Polyacrylate, 15--45 parts of glycerol, 2-8 parts of gelatin, 0.01-7 parts of propylene glycol (v/v), carboxymethyl fibre
Tie up plain 6-30 parts of sodium, 20~80 parts of deionized water；
Step 4, medicinal extract, far-infared ceramic powder and step 3 mesostroma that will be produced in volatile oil that step 1 extracts, step 2
Raw material mixes, and is applied on non-woven fabrics and patch is made.
It is exemplified below several typical using external use plaster of the present invention healing case:
1, Zhu, female 33 years old, suffer from the proliferation of mammary gland more than 3 years.Once it took Western medicine, Chinese medicine but effect to be good or bad, centre is more adopted
It is all no to obtain good effect with the methods of Chinese medicinal plaster, acupuncture, physical therapy.Because Zhu family reason is often angry, while skin
Skin is more sensitive, and when using traditional patch, every patch can only be pasted 2 hours or so, otherwise just will appear itch, the symptoms such as fash.It uses
After product of the present invention, every patch can be pasted 24-48 hours, adhere to that hyperplasia lump disappeared using 2 months.
2, Sichuan Mrs Du, because of the left cream of mammary gland carcinectomy before 43 years old, 2 years, after 2 years, and it was hidden to find that right cream starts
Bitterly, and on breast there are many lumps, after the present invention, after 2 days, pain weakens, and adheres to having used always checking after two months
Lump disappears.
3, Miss Guo 27 years old, before half a year, feels that two mammary swellings pain is pierced like needle, two arms are also taken out bitterly, and raising one's arm has suddenly
Difficulty, hand, which touches painful area picture, lump.Many Western medicine, Chinese medicine have been taken, have all been to relieve pain at that time, have been returnd to the past later.Because of me
Skin allergy is itched, red and swollen, the big influence work and life of flavour of a drug using conventional patch skin.After invention product, the 2nd day
Swollen breasts mitigate, and arm takes out that pain is basic to disappear, and feeling of pain is without going to hospital to check, discovery lump, which softens, to be reduced after 13 days
, and Ge Yuezaiqu hospital check has been crossed, the lump in the breast of two sides disappears.
The invention has the benefit that the present invention is with dispersing stagnated hepatoqi, activating microcirculation and removing stasis medicinal, clearing heat and detoxicating, swelling and pain relieving Chinese medicine
Material is primary raw material, cooperates far-infrared ray material, and allergy, viscosity is not moderate for manufactured external use plaster, is affixed on proliferation of mammary gland position,
Can rapid swelling and pain relieving, the external use plaster trial employment period of the present invention, effective percentage 98% or more, 72% or more cure rate, patient is anti-
Reflect analgesic is fast, dissipating bind thoroughly, it is light without allergy, Chinese medicine odor.
Specific embodiment
The present invention is described further with reference to embodiments, but the invention is not limited to embodiments.
Embodiment 1.
A kind of external use plaster for treating the proliferation of mammary gland is prepared by following raw material in parts by weight: 3 parts of Snakegourd Fruit, the seed of cowherb
4 parts, 2 parts of edible tulip, 2 parts of caulis bambusae in taenian, 3 parts of peach kernel, 2 parts of Paris polyphylla, 4 parts of dandelion, 2 parts of safflower, 3 parts of peach kernel, Prunella vulgaris 4 part, day
2 parts of winter, 2 parts of rhizoma cyperi, 5 parts of far-infared ceramic powder.
The preparation method is as follows:
Step 1: 5 parts of far-infared ceramic powders being ground spare, dandelion, safflower, Prunella vulgaris, the rhizoma cyperi of above-mentioned components by weight percent is taken to add
8 times of amounts of water are impregnated 4 hours, are extracted with the way of distillation, are collected 2 times of amounts for slightly slipping that liquid is raw material, are carried out redistillation to liquid is slightly slipped,
Volatile oil is collected, it is spare；
Step 2: by step 1 extraction slag and distillate mix with remaining raw material, extracted 2 times with decocting method, 8 times for the first time
Amount is extracted 2 hours, and extracting solution is collected, and second of 6 times of amount is extracted 1.5 hours, is collected and is merged extracting solution twice, and filtering is concentrated into
Relative density is 0.8-1.4 medicinal extract (60 DEG C of survey)；
Step 3 does patch substrate, specially 5 parts of polyvinylpyrrolidone, natrium adetate 0.1 using hydrophilic matrix raw material
Part, 6 parts of Sodium Polyacrylate, 30 parts of glycerol, 2-8 parts of gelatin, 1 part of propylene glycol (v/v), 20 parts of sodium carboxymethylcellulose, deionization
60 parts of water；
Step 4, medicinal extract, far-infared ceramic powder and step 3 mesostroma that will be produced in volatile oil that step 1 extracts, step 2
Raw material mixes, and is applied on non-woven fabrics and patch is made.
Embodiment 2
A kind of external use plaster for treating the proliferation of mammary gland is prepared by following raw material in parts by weight: 2 parts of Snakegourd Fruit, the seed of cowherb
3 parts, 1 part of edible tulip, 1 part of caulis bambusae in taenian, 3 parts of peach kernel, 1.5 parts of Paris polyphylla, 3 parts of dandelion, 1 part of safflower, 2 parts of peach kernel, 3 parts of Prunella vulgaris,
2 parts of asparagus fern, 1 part of rhizoma cyperi, 3 parts of far-infared ceramic powder.
A kind of external use plaster for treating the proliferation of mammary gland of the present invention the preparation method is as follows:
Step 1: 3 parts of far-infared ceramic powders being ground spare, dandelion, safflower, Prunella vulgaris, the rhizoma cyperi of above-mentioned components by weight percent is taken to add
Water impregnates 8 times and measures 3 hours, is extracted with the way of distillation, collects 2 times of amounts for slightly slipping that liquid is raw material, carries out redistillation to liquid is slightly slipped,
Volatile oil is collected, it is spare；
Step 2: by step 1 extraction slag and distillate mix with remaining raw material, extracted 2 times with decocting method, 8 times for the first time
Amount is extracted 2 hours, and extracting solution is collected, and second of 6 times of amount is extracted 1.5 hours, is collected and is merged extracting solution twice, and filtering is concentrated into
Relative density is 0.8-1.4 medicinal extract (60 DEG C of survey)；
Step 3 does patch substrate, specially 3 parts of polyvinylpyrrolidone, natrium adetate 0.5 using hydrophilic matrix raw material
Part, 4 parts of Sodium Polyacrylate, 20 parts of glycerol, 3 parts of gelatin, 0.5 part of propylene glycol (v/v), 10 parts of sodium carboxymethylcellulose, deionization
35 parts of water；
Step 4, medicinal extract, far-infared ceramic powder and step 3 mesostroma that will be produced in volatile oil that step 1 extracts, step 2
Raw material mixes, and is applied on non-woven fabrics and patch is made.
Above-described embodiment, only presently preferred embodiments of the present invention, is not intended to limit the invention practical range, therefore all with this
The equivalence changes that content described in invention claim is done should all be included within scope of the invention as claimed.
Claims (2)
1. a kind of external use plaster for treating the proliferation of mammary gland, it is characterised in that: in parts by weight, prepared by following raw material: melon
2-3 parts of beach wormwood, 3-4 parts of the seed of cowherb, 1-2 parts of edible tulip, 1-2 parts of caulis bambusae in taenian, 3-4 parts of peach kernel, 1-3 parts of Paris polyphylla, 2-5 parts of dandelion,
1-3 parts of safflower, 2-4 parts of peach kernel, 2-5 parts of Prunella vulgaris, 1-3 parts of asparagus fern, 1-3 parts of rhizoma cyperi, 0.1-10 parts of far-infared ceramic powder.
2. a kind of preparation method for the external use plaster for treating the proliferation of mammary gland as described in claim 1, which is characterized in that including such as
Lower step:
Step 1: 0.1-10 parts of far-infared ceramic powders are ground it is spare, take the dandelion of above-mentioned components by weight percent, safflower, Prunella vulgaris,
8 times of amounts of fragrant additional water are impregnated 2-4 hour, are extracted with the way of distillation, and 2 times of amounts for slightly slipping that liquid is raw material are collected, to it is thick slip liquid into
Volatile oil is collected in row redistillation, spare；
Step 2: by step 1 extraction slag and distillate mix with remaining raw material, extracted 2 times with decocting method, 8 times for the first time
Amount is extracted 2 hours, and extracting solution is collected, and second of 6 times of amount is extracted 1.5 hours, is collected and is merged extracting solution twice, and filtering is concentrated into
Relative density is 0.8-1.4 medicinal extract (60 DEG C of survey)；
Step 3 does patch substrate, specially polyvinylpyrrolidone 3-6 parts, natrium adetate using hydrophilic matrix raw material
0.01-2 parts, 3--9 parts of Sodium Polyacrylate, 15--45 parts of glycerol, 2-8 parts of gelatin, 0.01-7 parts of propylene glycol (v/v), carboxymethyl fibre
Tie up plain 6-30 parts of sodium, 20~80 parts of deionized water；
Step 4, medicinal extract, far-infared ceramic powder and step 3 mesostroma that will be produced in volatile oil that step 1 extracts, step 2
Raw material mixes, and is applied on non-woven fabrics and patch is made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201811502628.6A CN109224004A (en) | 2018-12-10 | 2018-12-10 | A kind of external use plaster and preparation method thereof for treating the proliferation of mammary gland |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811502628.6A CN109224004A (en) | 2018-12-10 | 2018-12-10 | A kind of external use plaster and preparation method thereof for treating the proliferation of mammary gland |
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| CN109224004A true CN109224004A (en) | 2019-01-18 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111905082A (en) * | 2020-08-26 | 2020-11-10 | 广东汝伦舒生物科技有限公司 | External ointment for treating hyperplasia of mammary glands and preparation method thereof |
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| CN101417013A (en) * | 2008-11-10 | 2009-04-29 | 北京天科仁祥医药科技有限公司 | Traditional Chinese medicine cataplasm for treating rheumatism and ostalgia and preparation method thereof |
| CN105688217A (en) * | 2016-01-22 | 2016-06-22 | 贵州佰诺康生物医药开发有限公司 | Matrix for external patch and external patch as well as mammary gland hyperplasia treating patch prepared from matrix |
| CN106606630A (en) * | 2015-10-21 | 2017-05-03 | 杨曼生 | Moringa oleifera plant essence for mammary gland maintenance |
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| CN101417013A (en) * | 2008-11-10 | 2009-04-29 | 北京天科仁祥医药科技有限公司 | Traditional Chinese medicine cataplasm for treating rheumatism and ostalgia and preparation method thereof |
| CN106606630A (en) * | 2015-10-21 | 2017-05-03 | 杨曼生 | Moringa oleifera plant essence for mammary gland maintenance |
| CN105688217A (en) * | 2016-01-22 | 2016-06-22 | 贵州佰诺康生物医药开发有限公司 | Matrix for external patch and external patch as well as mammary gland hyperplasia treating patch prepared from matrix |
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| CN111905082A (en) * | 2020-08-26 | 2020-11-10 | 广东汝伦舒生物科技有限公司 | External ointment for treating hyperplasia of mammary glands and preparation method thereof |
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Application publication date: 20190118 |