CN109223898A - A kind for the treatment of of rhinitis ointment and preparation method thereof - Google Patents
A kind for the treatment of of rhinitis ointment and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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Abstract
A kind for the treatment of of rhinitis ointment and preparation method thereof, belong to the field of Chinese medicines, the ointment includes henbane seed, the coptis, mountain Cape jasmine, kuh-seng, borneol, garden burnet, pure water, caustic soda, paraffin oil, all stone forests, wherein, henbane seed: the coptis: mountain Cape jasmine: kuh-seng: borneol: garden burnet: pure water: caustic soda: paraffin oil: the weight fraction ratio of all stone forests is 100:30~40:30~40:30~40:6~8:30~40:30~40:12~15:12~15:6~8, utilize the present invention, operative treatment can be removed from, remove patients surgery pain from, medical expense is greatly lowered, the various discomforts of patient's rhinitis bring can be reduced, eliminate the inferiority complex of patient, promote the self-confidence of patient.
Description
Technical field
The present invention relates to a kind of ointment and preparation method thereof, in particular to a kind for the treatment of of rhinitis ointment and preparation method thereof,
Belong to the field of Chinese medicines.
Background technique
Rhinitis, that is, nasal cavity inflammatory disease is virus, bacterium, allergen, various physical and chemical factors and certain systemic diseases
The inflammation of caused bronchia mucosal.The main pathological change of rhinitis will lead to occur bronchia mucosal hyperemia, swelling, exudation, hyperplasia,
The state of an illness such as atrophy or necrosis occur.
Cause the type of rhinitis about there are several types of may, 1, virus infection, 2, inherent cause, 3, schneiderian membrance it is susceptible
Property, schneiderian membrance neurological susceptibility includes (1) inhalant allergen (2) eating property allergenicity allergen.
Wherein, virus infection is not its primary cause of disease, or secondary bacterial infection on the basis of virus infection.It has been known that there is
More than 100 kinds of viruses can cause this disease, most commonly rhinovirus, followed by influenza and parainfluenza virus, adenovirus, coronal disease
Poison, Coxsackie virus and mucus and paramyxovirus etc..Viral transmission mode mainly passes through respiratory tract sucking, followed by passes through
Contaminated body or food enter body.
Inherent cause has allergy family history person to be susceptible to suffer from this disease.Patient home personnel have asthma, nettle rash or drug more
Allergies.This patient was referred to as atopic individuals in the past, and the ability for generating IgE antibody in vivo is higher than normal person.But someone in recent years
It was found that the twin disease incidence with general population is without significant difference.
The generation of schneiderian membrance neurological susceptibility is derived from the frequent stimulation of antigenic substance, but its susceptible degree then regards in nasal mucosa
The ability of mast cell, the quantity of basophilic granulocyte and release chemical mediator.Now it has proven convenient that allergic rhinitis patients schneiderian membrance
In above-mentioned cell quantity be not only above normal person, and have it is stronger release chemical mediator ability.
Schneiderian membrance neurological susceptibility, which refers to, inhalant allergen in rhinitis, and is specifically divided into 1. pollen 2. fungi 3. room dirt
Mite 4. animal scurf 5. factors such as indoor dust, eating property allergen refers to be entered human body and is caused the change of sniffle by alimentary canal
Answer original matter.
There is rebound phenomenons in the treatment for rhinitis, when in particular with western medicine, be usually present it is quick, repeatedly
Also fast problem, makes patient suffer untold misery, and how could eradicate rhinitis, is patient or even medical institutions ear-nose-throat department medical worker
Extremely concern problem, in recent years, therefore will treat rhinitis to place on the research of Chinese medicine is phase using Chinese medicine treatment rhinitis
One Chinese medicine project of pass personnel research.
Summary of the invention
For rhinitis, doctor trained in Western medicine has the case where being easy recurrence over the course for the treatment of, and the present invention provides a kind for the treatment of of rhinitis ointment
And preparation method thereof, the purpose is to utilize Chinese medicine, rhinitis is treated, virus infection is prevented, improves anti-inflammatory effect, reduction than in is filled
Blood phenomenon improves patient's nasal cavity body Abwehrkraft des Koepers, cures rhinitis.
The technical scheme is that a kind for the treatment of of rhinitis ointment, the ointment include henbane seed, the coptis, mountain Cape jasmine, kuh-seng,
Borneol, garden burnet, pure water, caustic soda, paraffin oil, all stone forests, wherein henbane seed: the coptis: mountain Cape jasmine: kuh-seng: borneol: garden burnet: pure
Water: caustic soda: paraffin oil: the weight fraction ratio of all stone forests is 100:30~40:30~40:30~40:6~8:30~40:30
~40:12~15:12~15:6~8.
A kind of preparation method for the treatment of of rhinitis ointment, the preparation method of the treatment of rhinitis ointment are made according to the following steps
It is standby:
1) according to henbane seed: the coptis: mountain Cape jasmine: kuh-seng: borneol: garden burnet: pure water: caustic soda: paraffin oil: the parts by weight of all stone forests
Than distinguishing for 100:30~40:30~40:30~40:6~8:30~40:30~40:12~15:12~15:6~8 ratio
Weigh drug；
2) weighed henbane seed, the coptis, mountain Cape jasmine, kuh-seng, borneol, garden burnet are mixed first, is pulverized into powder, utilizes 100 mesh
Sieve；
3) filter residue after sieving is repeated the above steps and is pulverized and sieved, until all sievings；
4) powder obtained after being sieved in step 2 and step 3) is uniformly mixed；
4) with weighed pure water, caustic soda, paraffin oil, all stone forest modulation steps 4) obtained powder bottles sealing after paste
It is spare.
The good effect that the present invention has is: by the way that this ointment to be applied in nasal cavity, being able to solve patient's nasal obstruction, smell
The symptoms such as decline, grasp too much, and can not only play antiinflammation, and can prevent the appearance of nasal cavity hyperemia phenomenon, especially
It is that can be improved nasal cavity body Abwehrkraft des Koepers, thus prevents virus, reduces mast cell in nasal mucosa, solve patient
The phenomenon of asthma, nettle rash or drug allergy etc. can remove operative treatment from using the present invention, remove patients surgery pain from, substantially
Degree reduces medical expense, reduces the various discomforts of patient's rhinitis bring, eliminates the inferiority complex of patient, improves patient oneself
Confidence.
Summary of the invention
Technical solution of the present invention is illustrated using specifically embodiment below.
Just efficacy of drugs used in the present invention is illustrated respectively first.
Henbane seed: relieving spasm and pain feels at ease to determine epilepsy, cures mainly epigastric pain, rheumatism numbness, gout carious pain, injuries from falls as well, and asthma is coughed
Incessantly, dysentery rectal prolapse, demented, frightened epilepsy, carbuncle sore tumefacting virus.
The coptis: heat-clearing and damp-drying drug, purging fire for removing toxin.For damp and hot feeling of fullness, acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, internal heat are vomitted
High Sheng, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, toothache are quenched one's thirst, carbuncle swells furunculosis；Eczema, wet sore, purulent ear canal are controlled outside.Prepared RHIZOMA COPTIDIS with vino
It is burning hot to be apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For hot eyes, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach anti-vomiting.It is mutually tied for fever and chills, damp and hot middle resistance, feeling of fullness vomiting.
Cornel coptis is relaxed liver anti-vomiting.For liver-stomach disharmony, acid regurgitation is vomitted.
Mountain Cape jasmine: leaf, flower, fruit and the root of mountain Cape jasmine can be used as medicine, and have effects that heat-clearing, purging intense heat, removing toxic substances, cool blood；Mountain mast
Cotyledon: it is used for traumatic injury.Mashed with fresh leaf and spread on affected part, can activating microcirculation and removing stasis medicinal, swelling and pain relieving.Its juice washes the treatment of infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid, dissipates
Carbuncle；Fructus gardeniae: clearing lung-heat, cool blood.With three and honey same decoction a little are spent, cough with lung heat is controlled, yellow phlegm is spat.With flower several pieces,
Drying last nasal insufflation, to control nosebleed more than；Fruit, the root of mountain Cape jasmine: control febrile disease dysphoria be insomnia, yellow croaker, stranguria syndrome, hot eyes, pharyngalgia, bloody flux,
Bleeding from five sense organs or subcutaneous tissue, hematuria, pathopyretic ulcer, strain swelling and pain etc..Mountain Cape jasmine can control pyreticosis restlessness of asrhenia type and insomnia, jaundice, and stranguria syndrome is quenched one's thirst, hot eyes, pharyngalgia,
It spits blood, bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, pathopyretic ulcer, strain swelling and pain.
Kuh-seng: it is cold in nature, there is the effect of heat-clearing and damp-drying drug, desinsection, kuh-seng bath can remove damp-heat in lower-JIAO, and desinsection is antipruritic,
Have a good relaxation effect to pruitus, vegetable Chinese herbal medicine can Bergamot Mint Extract, dredge and restrain pore, remove skin
Endotoxin contamination, book on Chinese herbal medicine nutrition abundant, promotes the growth and reparation of damaged blood vessels nerve cell, it is thin to restore subcutaneous capillary
Born of the same parents' vigor, skin reproduction is compact fine and smooth, plays the role of beauty and skin care.Matrine to auricle edema caused by mouse knoting oil,
The exudation of mouse peritoneal caused by acetic acid increase, Rat Carrageenan colloidality footpad swelling, there is inhibiting effect.
Borneol: borneol point is natural and synthesizes.And experiments have shown that no matter natural or synthesize, in borneol concentration higher than 0.5%
When, there is identical powerful bacteriostasis.Wherein effect of the isoborneol to croton oil simultaneously, can exclude liquid oedema, play
The effect of anti-inflammatory.
Garden burnet: it is cold in nature, there is Qinghuo Jiedu effect, be used for abscess of throat, aphthae, hot eyes；Leukorrhea with reddish discharge can be treated,
Sore, carbuncle and painful swelling, scald, snakebite and bugbite；It can also be used in for malignant sore, disappear wine, and except quenching one's thirst, mending wound, postpartum internal plug absolutely can make
Metal-inflicted wound cream.Leakage is more than in main, and blood is insufficient, has the effect of hemostasis.
Pure water: dilution, reconciliation effect are played in the present invention.
Caustic soda: a kind of highly basic, generally sheet or block-shape morphology, (heat release when being dissolved in water) soluble easily in water simultaneously form alkalinity
Solution, separately there is a hygroscopy, the vapor and a kind of alkaline cleaner in easy draw air and in drug, is dissolved in ethyl alcohol and sweet
Oil.
Paraffin oil: being suitble to a kind of lubricant used in human body, from when human body insertion conduit or cavity inspection
Lubricating action, when oral or bowel lavage, can be used for the relax bowel and defecation of human body, play the role of lubrication enteron aisle, soften stool.
Vaseline: being applied to face, hand, foot or body skin, moistens moisturizing；Nasal cavity inner membrance is coated in avoid because of too dry
And bleed or the people of nosebleed can be coated in nostril prevent Continuous hemorrhage；It is applied on lip as lip-stick, grease composition
It can keep lip moisture；It is coated in when flu on the skin of nose and reddens in order to avoid blowing one's nose and excessively rubbing；It can avoid because of wet urine
Cloth Long Term Contact skin and cause eczema；The patient of even canker sore first can also dry affected part with paper handkerchief, be then coated with one
Layer vaseline.It can prevent ulcer from contacting intraoral acidic materials in this way, accelerate the healing of ulcer.
Embodiment
It is using the present invention below in clinical treatment embodiment.
1) according to henbane seed, the coptis, mountain Cape jasmine, kuh-seng, borneol, garden burnet, pure water, caustic soda, the stone of embodiment 1-6 in table 1
Wax oil, all stone forests weight fraction ratio weigh drug respectively；
2) henbane seed weighed in each embodiment, the coptis, mountain Cape jasmine, kuh-seng, borneol, garden burnet are mixed respectively, is ground into powder
Shape utilizes the sieve of 100 mesh；
3) filter residue after sieving is repeated the above steps respectively and is pulverized and sieved, until all sievings；
4) powder obtained after being sieved in step 2 and step 3) respectively is uniformly mixed；
4) respectively with weighed pure water, caustic soda, paraffin oil, all stone forest modulation steps 4) obtained powder bottles after paste
Sealing, enclosing capacity in the present embodiment is in the low bottleneck medicine bottle of 50g.
Weight ratio in each embodiment is referring to table 1.
Table 1:
In table 1,2 treatments are carried out using the present invention, the healing that most of patient obtains, only pole few patients increase the 3rd
Secondary treatment.
The use method method of this ointment is:
1, it is smeared in topical intranasal using more cacaine swab sticks, anaesthetizes nasal cavity；
2, it is put in using the cotton balls that end is coated with ointment of the present invention on the inside of the corresponding nasal cavity in the loose outside of concha, is gently pressed
Under, delay is taken out after 15 minutes；
3, when needing to carry out second or treat for the third time, above-mentioned 1,2 program is repeated.
General rhinitis, can cure for 1-2 times, seriousness rhinitis, can cure for 3 times, and without being hospitalized, longest is observed half
Hour.Even patient's treatment number of times very serious are not more than 5 times.
The present invention carries out clinical treatment by the way that this ointment to be applied in nasal cavity, for 6 batches of total 221 human patient, and office obtains
Arriving recovery from illness, the symptoms such as this ointment is able to solve patient's nasal obstruction, hyposphresia, grasps too much can not only play antiinflammation, and
The appearance of nasal cavity hyperemia phenomenon can be prevented, nasal cavity body Abwehrkraft des Koepers is especially can be improved, thus prevents disease
Poison reduces mast cell in nasal mucosa, solves the phenomenon of patient's asthma, nettle rash or drug allergy etc., utilizes the present invention
Operative treatment can be removed from, remove patients surgery pain from, medical expense is greatly lowered, it is various not to reduce patient's rhinitis bring
It is suitable, the inferiority complex of patient is eliminated, the self-confidence of patient is improved.
Claims (2)
1. a kind for the treatment of of rhinitis ointment, it is characterised in that: the ointment include henbane seed, the coptis, mountain Cape jasmine, kuh-seng, borneol,
Elm, pure water, caustic soda, paraffin oil, all stone forests, wherein henbane seed: the coptis: mountain Cape jasmine: kuh-seng: borneol: garden burnet: Java brucea: pure
Water: caustic soda: paraffin oil: the weight fraction ratio of all stone forests is 100:30~40:30~40:30~40:6~8:30~40:30
~40:12~15:12~15:6~8.
2. a kind of preparation method for the treatment of of rhinitis ointment, it is characterised in that: the preparation method of the treatment of rhinitis ointment according to
Lower step preparation:
1) according to henbane seed: the coptis: mountain Cape jasmine: kuh-seng: borneol: garden burnet: pure water: caustic soda: paraffin oil: the parts by weight of all stone forests
Than dividing for 100:30~40:30~40:30~40:6~8:30~40:30~40:12~15:12~15:6~8 ratio
Also known as take drug；
2) weighed henbane seed, the coptis, mountain Cape jasmine, kuh-seng, borneol, garden burnet are mixed first, is pulverized into powder, utilizes 100 mesh
Sieve；
3) filter residue after sieving is repeated the above steps and is pulverized and sieved, until all sievings；
4) powder obtained after being sieved in step 2 and step 3) is uniformly mixed；
4) with weighed pure water, caustic soda, paraffin oil, all stone forest modulation steps 4) obtained powder bottles sealing after paste
It is spare.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811522096.2A CN109223898A (en) | 2018-12-13 | 2018-12-13 | A kind for the treatment of of rhinitis ointment and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811522096.2A CN109223898A (en) | 2018-12-13 | 2018-12-13 | A kind for the treatment of of rhinitis ointment and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110742930A (en) * | 2019-11-08 | 2020-02-04 | 叶草堂鼻炎医疗用品(深圳)有限公司 | Rhinitis ointment |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1120447A (en) * | 1994-10-11 | 1996-04-17 | 童鹰 | Rhinitis liniment and its prepn. |
| CN107334991A (en) * | 2017-08-18 | 2017-11-10 | 刘大林 | A kind of Chinese medicine for treating rhinitis and preparation method |
-
2018
- 2018-12-13 CN CN201811522096.2A patent/CN109223898A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1120447A (en) * | 1994-10-11 | 1996-04-17 | 童鹰 | Rhinitis liniment and its prepn. |
| CN107334991A (en) * | 2017-08-18 | 2017-11-10 | 刘大林 | A kind of Chinese medicine for treating rhinitis and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 蒲昭和: "验方选登", 《家庭医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110742930A (en) * | 2019-11-08 | 2020-02-04 | 叶草堂鼻炎医疗用品(深圳)有限公司 | Rhinitis ointment |
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Application publication date: 20190118 |