CN109222106A - A kind of probiotic composition and the preparation method and application thereof helping children's appetite-stimulating and indigestion-relieving - Google Patents
A kind of probiotic composition and the preparation method and application thereof helping children's appetite-stimulating and indigestion-relieving Download PDFInfo
- Publication number
- CN109222106A CN109222106A CN201811180850.9A CN201811180850A CN109222106A CN 109222106 A CN109222106 A CN 109222106A CN 201811180850 A CN201811180850 A CN 201811180850A CN 109222106 A CN109222106 A CN 109222106A
- Authority
- CN
- China
- Prior art keywords
- parts
- appetite
- indigestion
- stimulating
- relieving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 49
- 201000006549 dyspepsia Diseases 0.000 title claims abstract description 46
- 239000006041 probiotic Substances 0.000 title claims abstract description 41
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 41
- 230000000529 probiotic effect Effects 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 16
- 239000000843 powder Substances 0.000 claims abstract description 51
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 31
- 239000000052 vinegar Substances 0.000 claims abstract description 26
- 235000021419 vinegar Nutrition 0.000 claims abstract description 26
- 235000011230 Prunus domestica subsp. italica Nutrition 0.000 claims abstract description 25
- 244000249693 Reneklode Species 0.000 claims abstract description 25
- 241000193749 Bacillus coagulans Species 0.000 claims abstract description 21
- 244000242564 Osmanthus fragrans Species 0.000 claims abstract description 21
- 235000019083 Osmanthus fragrans Nutrition 0.000 claims abstract description 21
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 21
- 229940054340 bacillus coagulans Drugs 0.000 claims abstract description 21
- 239000011701 zinc Substances 0.000 claims abstract description 21
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 21
- UQZIYBXSHAGNOE-USOSMYMVSA-N Stachyose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](CO[C@@H]2[C@@H](O)[C@@H](O)[C@@H](O)[C@H](CO)O2)O1 UQZIYBXSHAGNOE-USOSMYMVSA-N 0.000 claims abstract description 19
- UQZIYBXSHAGNOE-XNSRJBNMSA-N stachyose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO[C@@H]3[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O3)O)O2)O)O1 UQZIYBXSHAGNOE-XNSRJBNMSA-N 0.000 claims abstract description 19
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims abstract description 14
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims abstract description 14
- 235000009685 Crataegus X maligna Nutrition 0.000 claims abstract description 14
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims abstract description 14
- 235000009486 Crataegus bullatus Nutrition 0.000 claims abstract description 14
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims abstract description 14
- 235000009682 Crataegus limnophila Nutrition 0.000 claims abstract description 14
- 235000004423 Crataegus monogyna Nutrition 0.000 claims abstract description 14
- 235000002313 Crataegus paludosa Nutrition 0.000 claims abstract description 14
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims abstract description 14
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 claims abstract description 13
- 244000197580 Poria cocos Species 0.000 claims abstract description 12
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 12
- 239000004615 ingredient Substances 0.000 claims abstract description 11
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 6
- 235000019789 appetite Nutrition 0.000 claims abstract description 5
- 230000036528 appetite Effects 0.000 claims abstract description 5
- 230000029087 digestion Effects 0.000 claims abstract description 5
- 235000013325 dietary fiber Nutrition 0.000 claims abstract description 4
- 235000013311 vegetables Nutrition 0.000 claims abstract description 4
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims description 30
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 15
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- 241001092040 Crataegus Species 0.000 claims description 13
- 230000007071 enzymatic hydrolysis Effects 0.000 claims description 13
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 claims description 13
- 238000000855 fermentation Methods 0.000 claims description 13
- 230000004151 fermentation Effects 0.000 claims description 13
- 239000002002 slurry Substances 0.000 claims description 13
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 10
- 241000894006 Bacteria Species 0.000 claims description 7
- 102000004190 Enzymes Human genes 0.000 claims description 5
- 108090000790 Enzymes Proteins 0.000 claims description 5
- 229960005070 ascorbic acid Drugs 0.000 claims description 5
- 235000010323 ascorbic acid Nutrition 0.000 claims description 5
- 239000011668 ascorbic acid Substances 0.000 claims description 5
- 239000003381 stabilizer Substances 0.000 claims description 4
- 240000007126 Citrus medica var. sarcodactylis Species 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 238000004140 cleaning Methods 0.000 claims description 3
- 230000005684 electric field Effects 0.000 claims description 3
- 238000005360 mashing Methods 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 239000005720 sucrose Substances 0.000 claims description 3
- 230000032683 aging Effects 0.000 claims description 2
- HEBKCHPVOIAQTA-NGQZWQHPSA-N d-xylitol Chemical compound OC[C@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-NGQZWQHPSA-N 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 235000013372 meat Nutrition 0.000 claims description 2
- 238000012545 processing Methods 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 125000000185 sucrose group Chemical group 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 238000003825 pressing Methods 0.000 claims 3
- 238000002156 mixing Methods 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 230000000968 intestinal effect Effects 0.000 abstract description 4
- 235000019640 taste Nutrition 0.000 abstract description 2
- 240000000171 Crataegus monogyna Species 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 16
- 238000012360 testing method Methods 0.000 description 16
- 235000005686 eating Nutrition 0.000 description 7
- 230000037406 food intake Effects 0.000 description 7
- 235000012631 food intake Nutrition 0.000 description 7
- 102000004169 proteins and genes Human genes 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 230000013872 defecation Effects 0.000 description 6
- 235000018102 proteins Nutrition 0.000 description 6
- 239000003814 drug Substances 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 235000019621 digestibility Nutrition 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 241000193830 Bacillus <bacterium> Species 0.000 description 3
- 230000004596 appetite loss Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000004108 freeze drying Methods 0.000 description 3
- 230000002496 gastric effect Effects 0.000 description 3
- 208000019017 loss of appetite Diseases 0.000 description 3
- 235000021266 loss of appetite Nutrition 0.000 description 3
- 235000012054 meals Nutrition 0.000 description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000002550 fecal effect Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000002054 inoculum Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 235000021590 normal diet Nutrition 0.000 description 2
- 230000008855 peristalsis Effects 0.000 description 2
- 235000013406 prebiotics Nutrition 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- YTBSYETUWUMLBZ-QWWZWVQMSA-N D-threose Chemical compound OC[C@@H](O)[C@H](O)C=O YTBSYETUWUMLBZ-QWWZWVQMSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010059186 Early satiety Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 206010039921 Selenium deficiency Diseases 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 235000021245 dietary protein Nutrition 0.000 description 1
- 235000020930 dietary requirements Nutrition 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- FGXWKSZFVQUSTL-UHFFFAOYSA-N domperidone Chemical compound C12=CC=CC=C2NC(=O)N1CCCN(CC1)CCC1N1C2=CC=C(Cl)C=C2NC1=O FGXWKSZFVQUSTL-UHFFFAOYSA-N 0.000 description 1
- 229960001253 domperidone Drugs 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 235000014103 egg white Nutrition 0.000 description 1
- 210000000969 egg white Anatomy 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 235000019614 sour taste Nutrition 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of probiotic compositions and the preparation method and application thereof for helping children's appetite-stimulating and indigestion-relieving.The composition includes following ingredient according to the mass fraction: 0.3~1 part of bacillus coagulans, 15~35 parts of Greengage vinegar freeze-dried powder, sweet osmanthus freeze-dried powder 10~30,12~20 parts of Fructus Citri Sarcodactylis extract, 0.1~3 part of yeast zinc, 10~30 parts of stachyose, 0~12 part of hawthorn, 0~6 part of malt, 0~1.5 part of dark plum, 0~1.5 part of Poria cocos, 0~4 part of dried orange peel, 0~12 part of oligofructose, 0~6 part of water-soluble dietary fiber and 0~6 part of vegetables and fruits ferment powder.Aforesaid components are mixed to get the probiotic composition for helping children's appetite-stimulating and indigestion-relieving.The combination can quickly adjust intestinal flora balance and function of intestinal canal, improve appetite, and the stagnant solution that disappears is swollen, improves children's digestion and absorption function, and without side-effects to children, in good taste.
Description
Technical field
The present invention relates to a kind of composition, in particular to a kind of probiotic composition for helping children's appetite-stimulating and indigestion-relieving and its preparation
Method and application.
Background technique
The symptoms such as the common loss of appetite of children, abdominal fullness and distention, vomiting, this belongs to disorders of digestion scope, and the cause of disease is more
Kind of multiplicity: the foods such as excessive edible high protein, high-fat, high sugar；Trace element zinc, iron, selenium deficiency；Disease or drug shadow
It rings；Climatic effect；Exercise lack；Improper feeding etc..
Western medicine is treated frequently with Domperidone, enhances WeiDongLi Capsule, gastrointestinal peristalsis speed can be quickly promote after medication, is generated
Hunger increases appetite, but there are many infants to generate abdominal pain, the symptom of diarrhea, does not have simultaneously for gastrointestinal retention state
Improve.Chinese medicine is then often treated by spleen benefiting and stimulating the appetite, by promoting digestion and removing indigestions such as hawthorn, malt, endothelium corneum gigeriae gallis, improves internal taste
Transportation capabilities, but it does not help gastrointestinal peristalsis, and Chinese medical extract is partially bitter, children, which do not like, to be eaten, and to battalion
Element absorption function is supported without too big help.
Summary of the invention
The primary purpose of the present invention is that the shortcomings that overcoming the prior art and insufficient, a kind of children's appetite-stimulating and indigestion-relieving that helps is provided
Probiotic composition.
Another object of the present invention is to provide the preparation methods of the above-mentioned probiotic composition for helping children's appetite-stimulating and indigestion-relieving.
A further object of the present invention is to provide the applications of the above-mentioned probiotic composition for helping children's appetite-stimulating and indigestion-relieving.
The purpose of the invention is achieved by the following technical solution: a kind of probiotic composition helping children's appetite-stimulating and indigestion-relieving, packet
Containing following ingredient according to the mass fraction: 0.3~1 part of bacillus coagulans, 15~35 parts of Greengage vinegar freeze-dried powder, sweet osmanthus freeze-drying
Powder 10~30,12~20 parts of Fructus Citri Sarcodactylis extract, 0.1~3 part of yeast zinc, 10~30 parts of stachyose, 0~12 part of hawthorn, malt 0~
6 parts, 0~1.5 part of dark plum, 0~1.5 part of Poria cocos, 0~4 part of dried orange peel, 0~12 part of oligofructose, 0~6 part of water-soluble dietary fiber
With 0~6 part of vegetables and fruits ferment powder.
The probiotic composition for helping children's appetite-stimulating and indigestion-relieving preferably comprises following ingredient according to the mass fraction: solidifying
Tie 1 part of bacillus, 20~30 parts of Greengage vinegar freeze-dried powder, 10 parts of sweet osmanthus freeze-dried powder, 12 parts of Fructus Citri Sarcodactylis extract, yeast zinc 0.5
Part, 15 parts of stachyose.
The probiotic composition for helping children's appetite-stimulating and indigestion-relieving preferably includes following ingredient according to the mass fraction: solidifying
Tie 0.3~1 part of bacillus, 15~35 parts of Greengage vinegar freeze-dried powder, sweet osmanthus freeze-dried powder 10~30, Fructus Citri Sarcodactylis extract 12~20
Part, 0.1~3 part of yeast zinc, 10~30 parts of stachyose, 8~12 parts of hawthorn, 4~6 parts of malt, 0.5~1.5 part of dark plum, Poria cocos
0.5~1.5 part, 2~4 parts of dried orange peel, 8~12 parts of oligofructose；It more preferably include following ingredient according to the mass fraction: condensation bud
1 part of spore bacillus, 20~30 parts of Greengage vinegar freeze-dried powder, 10 parts of sweet osmanthus freeze-dried powder, 12 parts of Fructus Citri Sarcodactylis extract, 0.5 part of yeast zinc, water
15 parts of threose, 10 parts of hawthorn, 5 parts of malt, 1 part of dark plum, 1 part of Poria cocos, 3 parts of dried orange peel, 10 parts of oligofructose.
The bacillus coagulans are preferably bacillus coagulans BC30.
The Greengage vinegar freeze-dried powder is that green plum is mentioned by the green plum that low temperature vinegar fermentation and freeze drying process obtain
Object is taken, its fresh fragrant fruity and beneficiating ingredient are kept.
The Greengage vinegar freeze-dried powder is preferably made by the steps to obtain:
(1) medium well green plum is selected, cleaning, stoning obtain Green plum flesh；
(2) enzyme and color stabilizer are added in Green plum flesh, obtains enzymatic hydrolysis system, is digested；By the blueness after enzymolysis processing
The mashing juicing of plum pulp, is adjusted to 80~120g/L for pol with sugar, and adjusts pH value to 3~4, obtains Green plum flesh slurry；
(3) it is inoculated with saccharomyces cerevisiae in Green plum flesh slurry, in 15~25 DEG C of fermentations to production wine；
(4) it is then inoculated with acetic acid bacteria, and oligoxylans are added, is fermented in 13~23 DEG C sour to producing；
(5) it sterilizes, be aged；
(6) it is freeze-dried, obtains Greengage vinegar freeze-dried powder.
In step (2):
The enzyme is preferably pectase.
The dosage of the pectase is preferably 1000U/mL.
The color stabilizer is preferably one or both of citric acid and ascorbic acid.
The dosage of the citric acid is preferably that the concentration in the enzymatic hydrolysis system is mass volume ratio 0.1%.
The dosage of the ascorbic acid is preferably that the concentration in the enzymatic hydrolysis system is mass volume ratio 0.1%.
The enzymatic hydrolysis condition is preferably in 20~45 DEG C of 0.5~3h of enzymatic hydrolysis；More preferably in 40 DEG C of enzymatic hydrolysis 1h.
The sugar is preferably sucrose.
The pol is preferably 100g/L.
The pH value is preferably 3.5.
In step (3):
The saccharomyces cerevisiae is preferably highly active dry yeast.
The dosage of the saccharomyces cerevisiae is preferably the 0.1-1.0 ‰ for being equivalent to the Green plum flesh slurry quality.
The condition of the fermentation is preferably in 20 DEG C of fermentation 48h.
In step (4):
The dosage of the acetic acid bacteria is preferably the 0.1-1.0 ‰ for being equivalent to the Green plum flesh slurry quality.
The dosage of the xylo-oligosaccharide is preferably be equivalent to the Green plum flesh slurry quality 0.01~0.05%；More
Preferably 0.03%.
The condition of the fermentation is preferably in 18 DEG C of fermentation 48h.
In step (5):
The sterilizing and the ageing are handled preferably by impulse electric field to be realized.
The treatment conditions of the impulse electric field preferably handle 1~3h in 20~40kV/cm；More preferably in 30kV/
Cm handles 2h.
Mass volume ratio herein refers to g:mL.
The sweet osmanthus freeze-dried powder is that sweet osmanthus is lyophilized by Freeze Drying Technique, obtained sweet osmanthus freeze-dried powder.
The preparation method of the probiotic composition for helping children's appetite-stimulating and indigestion-relieving is to mix each ingredient according to formula ratio
It closes, obtains the probiotic composition for helping children's appetite-stimulating and indigestion-relieving.
The application for helping the probiotic composition of children's appetite-stimulating and indigestion-relieving to be helped in virgin appetite-stimulating and indigestion-relieving preparation in preparation.
One kind helping virgin appetite-stimulating and indigestion-relieving preparation, is by the probiotic composition for helping children's appetite-stimulating and indigestion-relieving and pharmaceutically may be used
It is mixed with the auxiliary material of receiving, powder, tablet, granule, capsule, liquid preparation is made.
The present invention has the following advantages and effects with respect to the prior art: the present invention can quickly adjust intestinal flora balance
And function of intestinal canal, improve appetite, the stagnant solution that disappears is swollen, improves children's digestion and absorption function, and without side-effects to children, and mouthfeel
It is good, it is deep to be liked by children, specific as follows:
1, the probiotic composition provided by the invention for helping children's appetite-stimulating and indigestion-relieving can be obviously shortened children's eating time, improve
Food-intake improves children's loss of appetite and indigestion symptom.
2, the probiotic composition provided by the invention for helping children's appetite-stimulating and indigestion-relieving may advantageously facilitate protein adsorption utilization, egg
White matter absorption rate improves 30% or so.
3, the probiotic composition provided by the invention for helping children's appetite-stimulating and indigestion-relieving, sweet and sour taste, the smell of fruits is very sweet, very by youngster
Child likes.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail, and embodiments of the present invention are not limited thereto.
Embodiment 1
(1) preparation of Greengage vinegar freeze-dried powder:
1) medium well green plum is selected, cleaning, stoning obtain Green plum flesh；
2) pectase (1000U/mL), citric acid 0.1% and ascorbic acid 0.1% are added in Green plum flesh, obtains enzyme
Enzymatic hydrolysis system, in 40 DEG C of enzymatic hydrolysis 1h；Mashing juicing, adding sucrose to pol is 100g/L, and adjusts pH value to 3.5, obtains green plum
Meat slurry；
3) inoculation yeast (Angel highly active dry yeast), the inoculum concentration of yeast is the 0.1% of Green plum flesh slurry, in 20
DEG C fermentation 48h.
4) it is inoculated with acetic acid bacteria (Jining Yu Yuan Biotechnology Co., Ltd, inoculum concentration are the 0.1% of Green plum flesh slurry), and is added
Enter oligoxylans (input amount is 0.03% that Green plum flesh is starched), in 18 DEG C of fermentation 48h；
5) 30kV/cm high-pressure pulse electric handles 2h.
6) it is freeze-dried, obtains Greengage vinegar freeze-dried powder.
(2) by bacillus coagulans BC30 (Ke Naiou trade (Shanghai) Co., Ltd.) 1 mass parts, Greengage vinegar freeze-dried powder
30 mass parts, 10 mass parts of sweet osmanthus freeze-dried powder (Huangshan Greenxtracts Co., Ltd.), Fructus Citri Sarcodactylis extract (found Hua Zhi in Ningbo
Object extractive technique Co., Ltd) 20 mass parts, 0.5 mass parts of yeast zinc (Angel Yeast Co., Ltd) and 15 matter of stachyose
It measures part to mix, crosses 60 meshes, obtain the probiotic composition for helping children's appetite-stimulating and indigestion-relieving.
Embodiment 2
By 0.3 mass parts of bacillus coagulans BC30,35 mass parts of Greengage vinegar freeze-dried powder, 20 mass of sweet osmanthus freeze-dried powder
Part, 12 mass parts of Fructus Citri Sarcodactylis extract, 3 mass parts of yeast zinc and 30 mass parts of stachyose mix, and crush, and cross 60 meshes, are helped
The probiotic composition of children's appetite-stimulating and indigestion-relieving.
Embodiment 3
By 0.6 mass parts of bacillus coagulans BC30,15 mass parts of Greengage vinegar freeze-dried powder, 30 mass of sweet osmanthus freeze-dried powder
Part, 15 mass parts of Fructus Citri Sarcodactylis extract, 0.1 mass parts of yeast zinc and 10 mass parts of stachyose mix, and crush, and cross 60 meshes, obtain
Help the probiotic composition of children's appetite-stimulating and indigestion-relieving.
Embodiment 4
By 1 mass parts of bacillus coagulans BC30,20 mass parts of Greengage vinegar freeze-dried powder, 10 mass parts of sweet osmanthus freeze-dried powder,
20 mass parts of Fructus Citri Sarcodactylis extract, 0.5 mass parts of yeast zinc, 15 mass parts of stachyose, 10 mass parts of hawthorn, 5 mass parts of malt, crow
1 mass parts of plum, 1 mass parts of Poria cocos, 3 mass parts of dried orange peel and 10 mass parts of oligofructose mix, and crush, and cross 60 meshes, are helped
The probiotic composition of children's appetite-stimulating and indigestion-relieving.
Embodiment 5
By 0.3 mass parts of bacillus coagulans BC30,35 mass parts of Greengage vinegar freeze-dried powder, 20 mass of sweet osmanthus freeze-dried powder
Part, 12 mass parts of Fructus Citri Sarcodactylis extract, 3 mass parts of yeast zinc, 30 mass parts of stachyose, 8 mass parts of hawthorn, 6 mass parts of malt, crow
0.5 mass parts of plum, 1.5 mass parts of Poria cocos, 2 mass parts of dried orange peel and 8 mass parts of oligofructose mix, and crush, and cross 60 meshes, obtain
Help the probiotic composition of children's appetite-stimulating and indigestion-relieving.
Embodiment 6
By 0.6 mass parts of bacillus coagulans BC30,15 mass parts of Greengage vinegar freeze-dried powder, 30 mass of sweet osmanthus freeze-dried powder
Part, 15 mass parts of Fructus Citri Sarcodactylis extract, 0.1 mass parts of yeast zinc, 10 mass parts of stachyose, 12 mass parts of hawthorn, 4 mass of malt
Part, 1.5 mass parts of dark plum, 0.5 mass parts of Poria cocos, 4 mass parts of dried orange peel and 12 mass parts of oligofructose mix, and crush, and cross 60 mesh
Sieve, obtains the probiotic composition for helping children's appetite-stimulating and indigestion-relieving.
Comparative example 1
By 1 mass parts of bacillus coagulans BC30,30 mass parts of dark plum, 10 mass parts of dried orange peel, 20 mass of Fructus Citri Sarcodactylis extract
Part, 0.5 mass parts of yeast zinc and 15 mass parts of stachyose mix, and crush, and cross 60 meshes, obtain helping the prebiotic of children's appetite-stimulating and indigestion-relieving
Bacteria composition.
Comparative example 2
By 1 mass parts of bacillus coagulans BC30,30 mass parts of hawthorn, 10 mass parts of dried orange peel, 20 mass of Fructus Citri Sarcodactylis extract
Part, 0.5 mass parts of yeast zinc and 15 mass parts of stachyose mix, and crush, and cross 60 meshes, obtain helping the prebiotic of children's appetite-stimulating and indigestion-relieving
Bacteria composition.
Comparative example 3
30 mass parts of Greengage vinegar freeze-dried powder, 10 mass parts of sweet osmanthus freeze-dried powder, 20 mass parts of Fructus Citri Sarcodactylis extract, yeast zinc
0.5 mass parts and 15 mass parts of stachyose mix, and cross 60 meshes, obtain the probiotic composition for helping children's appetite-stimulating and indigestion-relieving.
Comparative example 4
30 mass parts of hawthorn, 10 mass parts of dried orange peel, 20 mass parts of dark plum, 10 mass parts of Poria cocos, 12 mass parts of coloured malt, chicken
Interior golden 5 mass parts are extracted, and spray drying obtains the Chinese medicine composition for helping children's appetite-stimulating and indigestion-relieving.
Evaluation experimental:
1, children's eating time, food-intake and protein apparent digestibility, defecation frequency experiment.
Test crowd: 6-8 years old of selection indigestion (loss of appetite, stomach and intestine turgor, early satiety, gas are more etc.) it is voluntary tested
Person, every group of 10 people.
Test method: subject the eats unified canteen for 1-7 days (by " Dietary Reference Intakes of Chinese Residents
Handbook " dietary requirements are prepared within 6-8 years old, food materials containing protein will demand perfection and eat up, other appropriate), at 5-7 days, record every meal
Eating time and food-intake, are counted, and 3 days excrement of subject is in addition collected, and weighing measures fecal nitrogen amount, calculate protein
Apparent digestibility (before test), and record defecation frequency.It tests the 8-35 days, by original eating habit normal diet, respectively
Test group daily intakes given the test agent as required, and the intake of everyone daily given the test agent is 10g.It tests the 36-42 days, it is tested
Person eats unified canteen, and the eating time and food-intake of every meal is recorded at 40-42 days, and count, and in addition collects tested
3 days excrement of person, weighing measure fecal nitrogen amount, calculate protein apparent digestibility (after test), and record defecation frequency.
Blank control group, i.e. only normal diet are set, do not take any given the test agent；Probiotics control group is set, often
It takes probiotics bacillus coagulans BC30 0.13g.
2, test result is as shown in table 1~4:
The every meal eating time of table 1
| Before test average eating time (minute) | After test average eating time (minute) | Improvement rate (%) | |
| Blank control group | 27.3±6.3 | 26.8±5.5 | 1.8 |
| Probiotics control group | 26.9±5.5 | 24.6±5.2 | 8.6 |
| Embodiment 1 | 26.4±5.0 | 15.4±3.8 | 41.7 |
| Embodiment 2 | 27.5±6.0 | 16.6±4.5 | 39.6 |
| Embodiment 3 | 27.0±5.4 | 18.0±4.0 | 33.3 |
| Embodiment 4 | 26.6±5.8 | 15.0±5.1 | 43.6 |
| Embodiment 5 | 26.8±5.5 | 13.7±4.1 | 48.9 |
| Embodiment 6 | 26.2±6.1 | 14.5±4.8 | 44.6 |
| Comparative example 1 | 27.1±5.0 | 20.8±6.0 | 23.7 |
| Comparative example 2 | 27.0±6.4 | 20.2±5.7 | 25.2 |
| Comparative example 3 | 27.4±6.8 | 19.9±4.4 | 27.4 |
| Comparative example 4 | 26.6±6.5 | 20.8±4.8 | 21.8 |
2 food-intake of table
| Before test average food-intake (g/ days) | After test average food-intake (g/ days) | Improvement rate (%) | |
| Control group | 155±20 | 161±18 | 3.9 |
| Probiotics control group | 154±21 | 169±22 | 9.7 |
| Embodiment 1 | 158±25 | 214±15 | 35.4 |
| Embodiment 2 | 150±32 | 200±22 | 33.3 |
| Embodiment 3 | 155±20 | 201±20 | 29.7 |
| Embodiment 4 | 149±30 | 202±18 | 35.6 |
| Embodiment 5 | 162±17 | 225±12 | 38.9 |
| Embodiment 6 | 160±23 | 216±21 | 35.0 |
| Comparative example 1 | 161±24 | 188±19 | 16.8 |
| Comparative example 2 | 153±26 | 186±25 | 21.6 |
| Comparative example 3 | 158±27 | 197±20 | 24.7 |
| Comparative example 4 | 165±22 | 196±23 | 18.8 |
3 protein apparent digestibility of table
4 defecation frequency of table
| Average defecation frequency/day before test | Average defecation frequency/day after test | |
| Control group | 0.64 | 0.60 |
| Probiotics control group | 0.63 | 0.78 |
| Embodiment 1 | 0.61 | 1.03 |
| Embodiment 2 | 0.58 | 1.03 |
| Embodiment 3 | 0.60 | 0.87 |
| Embodiment 4 | 0.60 | 1.05 |
| Embodiment 5 | 0.65 | 1.05 |
| Embodiment 6 | 0.58 | 1.09 |
| Comparative example 1 | 0.67 | 0.86 |
| Comparative example 2 | 0.62 | 0.80 |
| Comparative example 3 | 0.59 | 0.84 |
| Comparative example 4 | 0.62 | 0.83 |
From the result of table 1~4, it can be seen that bacillus coagulans, Greengage vinegar freeze-dried powder, sweet osmanthus freeze-dried powder, fingered citron are extracted
The organic assembling of object, yeast zinc and stachyose can effectively improve the dyspeptic symptom of children, the work with appetite-stimulating and indigestion-relieving
With.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention,
It should be equivalent substitute mode, be included within the scope of the present invention.
Claims (10)
1. a kind of probiotic composition for helping children's appetite-stimulating and indigestion-relieving, it is characterised in that include following ingredient according to the mass fraction:
0.3~1 part of bacillus coagulans, 15~35 parts of Greengage vinegar freeze-dried powder, sweet osmanthus freeze-dried powder 10~30, Fructus Citri Sarcodactylis extract 12~20
Part, 0.1~3 part of yeast zinc, 10~30 parts of stachyose, 0~12 part of hawthorn, 0~6 part of malt, 0~1.5 part of dark plum, Poria cocos 0~
1.5 parts, 0~4 part of dried orange peel, 0~12 part of oligofructose, 0~6 part of water-soluble dietary fiber and 0~6 part of vegetables and fruits ferment powder.
2. the probiotic composition according to claim 1 for helping children's appetite-stimulating and indigestion-relieving, it is characterised in that comprising pressing matter below
Measure the ingredient of number meter: 1 part of bacillus coagulans, 20~30 parts of Greengage vinegar freeze-dried powder, 10 parts of sweet osmanthus freeze-dried powder, fingered citron are extracted
12 parts of object, 0.5 part of yeast zinc, 15 parts of stachyose.
3. the probiotic composition according to claim 1 for helping children's appetite-stimulating and indigestion-relieving, it is characterised in that including pressing matter below
Measure number meter ingredient: 0.3~1 part of bacillus coagulans, 15~35 parts of Greengage vinegar freeze-dried powder, sweet osmanthus freeze-dried powder 10~30,
12~20 parts of Fructus Citri Sarcodactylis extract, 0.1~3 part of yeast zinc, 10~30 parts of stachyose, 8~12 parts of hawthorn, 4~6 parts of malt, dark plum
0.5~1.5 part, 0.5~1.5 part of Poria cocos, 2~4 parts of dried orange peel, 8~12 parts of oligofructose.
4. the probiotic composition according to claim 3 for helping children's appetite-stimulating and indigestion-relieving, it is characterised in that including pressing matter below
Measure the ingredient of number meter: 1 part of bacillus coagulans, 20~30 parts of Greengage vinegar freeze-dried powder, 10 parts of sweet osmanthus freeze-dried powder, fingered citron are extracted
12 parts of object, 0.5 part of yeast zinc, 15 parts of stachyose, 10 parts of hawthorn, 5 parts of malt, 1 part of dark plum, 1 part of Poria cocos, 3 parts of dried orange peel, oligomeric fruit
10 parts of sugar.
5. the probiotic composition according to any one of claims 1 to 4 for helping children's appetite-stimulating and indigestion-relieving, it is characterised in that: institute
The bacillus coagulans stated are bacillus coagulans BC30.
6. the probiotic composition according to any one of claims 1 to 4 for helping children's appetite-stimulating and indigestion-relieving, it is characterised in that: institute
The Greengage vinegar freeze-dried powder stated is made by the steps to obtain:
(1) medium well green plum is selected, cleaning, stoning obtain Green plum flesh；
(2) enzyme and color stabilizer are added in Green plum flesh, obtains enzymatic hydrolysis system, is digested；By the green plum after enzymolysis processing
Meat mashing juicing, is adjusted to 80~120g/L for pol with sugar, and adjusts pH value to 3~4, obtains Green plum flesh slurry；
(3) it is inoculated with saccharomyces cerevisiae in Green plum flesh slurry, in 15~25 DEG C of fermentations to production wine；
(4) it is then inoculated with acetic acid bacteria, and oligoxylans are added, is fermented in 13~23 DEG C sour to producing；
(5) it sterilizes, be aged；
(6) it is freeze-dried, obtains Greengage vinegar freeze-dried powder.
7. the probiotic composition according to claim 6 for helping children's appetite-stimulating and indigestion-relieving, it is characterised in that:
In step (2):
The enzyme is pectase；
The dosage of the pectase is 1000U/mL；
The color stabilizer is one or both of citric acid and ascorbic acid；
The dosage of the citric acid is the calculating of mass volume ratio 0.1% by the concentration in the enzymatic hydrolysis system；
The dosage of the ascorbic acid is the calculating of mass volume ratio 0.1% by the concentration in the enzymatic hydrolysis system；
The enzymatic hydrolysis condition is in 20~45 DEG C of 0.5~3h of enzymatic hydrolysis；
The sugar is sucrose；
The pol is 100g/L；
The pH value is 3.5；
In step (3):
The saccharomyces cerevisiae is highly active dry yeast；
The dosage of the saccharomyces cerevisiae is calculated by the 0.1-1.0 ‰ for being equivalent to the Green plum flesh slurry quality；
The condition of the fermentation is in 20 DEG C of fermentation 48h；
In step (4):
The dosage of the acetic acid bacteria is calculated by the 0.1-1.0 ‰ for being equivalent to the Green plum flesh slurry quality；
The dosage of the xylo-oligosaccharide is calculated by be equivalent to the Green plum flesh slurry quality 0.01~0.05%；
The condition of the fermentation is in 18 DEG C of fermentation 48h；
In step (5):
The sterilizing and the ageing are to handle to realize by impulse electric field.
8. the preparation method of the described in any item probiotic compositions for helping children's appetite-stimulating and indigestion-relieving of claim 1~7, feature exist
In include the following steps: be by bacillus coagulans, Greengage vinegar freeze-dried powder, sweet osmanthus freeze-dried powder, Fructus Citri Sarcodactylis extract, yeast zinc,
Stachyose, hawthorn, malt, dark plum, Poria cocos, dried orange peel, oligofructose, water-soluble dietary fiber and vegetables and fruits ferment powder are according to formula ratio
Mixing, obtains the probiotic composition for helping children's appetite-stimulating and indigestion-relieving.
9. the described in any item probiotic compositions for helping children's appetite-stimulating and indigestion-relieving of claim 1~7 help virgin appetite-stimulating and indigestion-relieving in preparation
Application in preparation.
10. one kind helps virgin appetite-stimulating and indigestion-relieving preparation, it is characterised in that: be to help children to whet the appetite for claim 1~7 is described in any item
The probiotic composition to help digestion is mixed with pharmaceutically acceptable auxiliary material, and powder, tablet, granule, capsule or liquid is made
Body preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811180850.9A CN109222106A (en) | 2018-10-09 | 2018-10-09 | A kind of probiotic composition and the preparation method and application thereof helping children's appetite-stimulating and indigestion-relieving |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811180850.9A CN109222106A (en) | 2018-10-09 | 2018-10-09 | A kind of probiotic composition and the preparation method and application thereof helping children's appetite-stimulating and indigestion-relieving |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109222106A true CN109222106A (en) | 2019-01-18 |
Family
ID=65052544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811180850.9A Pending CN109222106A (en) | 2018-10-09 | 2018-10-09 | A kind of probiotic composition and the preparation method and application thereof helping children's appetite-stimulating and indigestion-relieving |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109222106A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110846294A (en) * | 2019-11-29 | 2020-02-28 | 怀化学院 | Recombinant pectinase, gene thereof, recombinant vector, preparation method and application |
| WO2023237683A1 (en) * | 2022-06-10 | 2023-12-14 | Dsm Ip Assets B.V. | Combinations comprising vitamin c and bacillus coagulans |
| WO2023237685A1 (en) * | 2022-06-10 | 2023-12-14 | Dsm Ip Assets B.V. | Combinations comprising vitamin and bacillus coagulans |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101041023A (en) * | 2007-04-24 | 2007-09-26 | 西安一枝刘制药有限公司 | Chinese traditional compound good for spleen and for improving appetite and food-digesting and the preparing method |
| CN101597583A (en) * | 2009-06-18 | 2009-12-09 | 浙江省农业科学院 | Its preparation of a kind of Greengage vinegar and application method |
| CN104491606A (en) * | 2015-01-15 | 2015-04-08 | 广东德鑫制药有限公司 | Traditional Chinese medicine composition and preparation and application thereof |
| CN107373228A (en) * | 2017-08-04 | 2017-11-24 | 南京江宁台湾农民创业园发展有限公司 | One kind improvement syrup of plum and its jelly |
| CN107616985A (en) * | 2017-10-01 | 2018-01-23 | 青岛东海药业有限公司 | Bacillus coagulans preparation and its application |
| CN108514121A (en) * | 2018-02-02 | 2018-09-11 | 云南中京国建投资有限公司 | A kind of defaecation, the symphysis unit composition of toxin expelling and its preparation and application |
| CN108634151A (en) * | 2018-05-14 | 2018-10-12 | 四川伟康生物科技有限公司 | A kind of probiotics egg nutrient powder and preparation method thereof |
-
2018
- 2018-10-09 CN CN201811180850.9A patent/CN109222106A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101041023A (en) * | 2007-04-24 | 2007-09-26 | 西安一枝刘制药有限公司 | Chinese traditional compound good for spleen and for improving appetite and food-digesting and the preparing method |
| CN101597583A (en) * | 2009-06-18 | 2009-12-09 | 浙江省农业科学院 | Its preparation of a kind of Greengage vinegar and application method |
| CN104491606A (en) * | 2015-01-15 | 2015-04-08 | 广东德鑫制药有限公司 | Traditional Chinese medicine composition and preparation and application thereof |
| CN107373228A (en) * | 2017-08-04 | 2017-11-24 | 南京江宁台湾农民创业园发展有限公司 | One kind improvement syrup of plum and its jelly |
| CN107616985A (en) * | 2017-10-01 | 2018-01-23 | 青岛东海药业有限公司 | Bacillus coagulans preparation and its application |
| CN108514121A (en) * | 2018-02-02 | 2018-09-11 | 云南中京国建投资有限公司 | A kind of defaecation, the symphysis unit composition of toxin expelling and its preparation and application |
| CN108634151A (en) * | 2018-05-14 | 2018-10-12 | 四川伟康生物科技有限公司 | A kind of probiotics egg nutrient powder and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 吴凌: "《舌尖上的中药：吃对了，补养全家》", 31 August 2016, 陕西科学技术出版社 * |
| 杨颖等: "青梅果醋的发酵工艺研究", 《中国食品学报》 * |
| 汤灿: "《破译绿色食品营养密码》", 31 January 2007, 广东经济出版社 * |
| 胡维勤: "《调养肠胃吃对才有效》", 30 June 2017, 黑龙江科学技术出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110846294A (en) * | 2019-11-29 | 2020-02-28 | 怀化学院 | Recombinant pectinase, gene thereof, recombinant vector, preparation method and application |
| CN110846294B (en) * | 2019-11-29 | 2022-05-17 | 怀化学院 | Recombinant pectinase, gene thereof, recombinant vector, preparation method and application |
| WO2023237683A1 (en) * | 2022-06-10 | 2023-12-14 | Dsm Ip Assets B.V. | Combinations comprising vitamin c and bacillus coagulans |
| WO2023237685A1 (en) * | 2022-06-10 | 2023-12-14 | Dsm Ip Assets B.V. | Combinations comprising vitamin and bacillus coagulans |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103704557A (en) | Preparation method and application of lycium barbarum fermented and concentrated juice | |
| CN103583991B (en) | Rice crust comprising radix polygonati officinalis and red date | |
| CN106954856A (en) | A kind of ferment dietary fiber and its preparation technology | |
| CN109222106A (en) | A kind of probiotic composition and the preparation method and application thereof helping children's appetite-stimulating and indigestion-relieving | |
| CN103431484A (en) | Asparagus fermented beverage and preparation method thereof | |
| CN108041201A (en) | A kind of Fu tea plants powder and preparation method thereof | |
| CN107080210A (en) | The formula of one seedling man's red acid soup, seedling man red acid soup and preparation method thereof | |
| KR20200076157A (en) | Composition for improving, treating or preventing intestinal function or inflammarory bowel disease comprising fermented rice as an active ingredient | |
| CN107223710A (en) | A kind of purple sweet potato yoghourt and preparation method thereof | |
| US20100285176A1 (en) | Fermentation product of aloe, method of manufacturing the same and functional foods using the same | |
| CN104472612A (en) | Natural yeast bread premixed flour for bread capable of coordinating intestines and stomach | |
| CN103876141A (en) | Composition with effects of clearing away lung-heat and detoxifying and preparation method and application thereof | |
| CN106360683A (en) | Dendrobium officinale and banana compound probiotic fermentation products and method thereof | |
| CN106173777A (en) | A kind of digestion promoting vegetable solid beverage and preparation method thereof | |
| CN101496568A (en) | Mung bean or pea dietary fiber and method for producing the same | |
| CN110214902A (en) | A kind of children's correction partial eclipse type selenium-rich complete nourishing powder | |
| CN101396056B (en) | Pine-needle tuckahoe teat and preparation method thereof | |
| CN105410924B (en) | Natto haw food and preparation method thereof | |
| CN103340391B (en) | Preparation method of flavored fruit and vegetable nutrient sauce, and flavored fruit and vegetable nutrient sauce prepared by same | |
| CN105613680A (en) | Liquorice cake for enhancing immunity of human body and making method thereof | |
| KR101443287B1 (en) | A making method of cookie bar containing probiotics composition | |
| CN108347978A (en) | The full garlic preparation method of lactobacillus-fermented | |
| JP2006006156A (en) | Liver function-enhancing health food | |
| CN102342513B (en) | Polygonatum odoratum nutritious powder | |
| CN110495521A (en) | A kind of mixed feed and preparation method thereof of rosy clouds cigarette hen egg anti-heat stress |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190118 |