CN109188007A - A kind of automatic clinical chemistry analyzer reaction tray and its application method - Google Patents
A kind of automatic clinical chemistry analyzer reaction tray and its application method Download PDFInfo
- Publication number
- CN109188007A CN109188007A CN201811035109.3A CN201811035109A CN109188007A CN 109188007 A CN109188007 A CN 109188007A CN 201811035109 A CN201811035109 A CN 201811035109A CN 109188007 A CN109188007 A CN 109188007A
- Authority
- CN
- China
- Prior art keywords
- reaction
- cup
- disk cover
- shaft
- slot
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
- G01N2035/0401—Sample carriers, cuvettes or reaction vessels
Abstract
The present invention is a kind of automatic clinical chemistry analyzer reaction tray and its application method, and reaction disk cover is furnished with fixed and movable cup bowl assembly, and be centrosymmetric distribution.Fixed cup bowl assembly is fixed on reaction disk cover outer rim.The movable bracket of movable cup bowl assembly is flexibly connected through shaft and shaft seat with disk cover outer rim is reacted.When reaction tray cap assemblies high-speed rotation, movable bracket with its glass of trench bottom dig by the top to outside reaction tray, and the angle of cut with horizontal plane is up to 120 °.Its application method is fluid sample to be centrifuged first to be added in the cup slot of movable bracket, sample-adding amount guarantees that movable bracket cup groove center is symmetrical；Reaction tray cap assemblies high-speed rotation, sample liquid centrifugation in reaction cup；Clear liquid is distributed in the reaction cup of fixed cup slot；Routinely test.Reaction tray cap assemblies of the invention and centrifuge are combined into one, and are not necessarily to otherwise processed sample liquid, improve testing efficiency, realize real full-automatic biochemical analysis.
Description
Technical field
The present invention relates to automatic clinical chemistry analyzer technologies, and in particular to a kind of automatic clinical chemistry analyzer reaction tray and its
Application method.
Background technique
Biochemical detection methods common at present have: colorimetric method, electrophoresis, immunoelectrophoresis, immunoturbidimetry transmitting are immune
Method, enzyme linked immunosorbent assay etc., most popular method are immunoturbidimetries.Immunoturbidimetry is divided into Immunity transmission turbidity again and exempts from
Epidemic disease dissipates color turbidimetry.Most of Biochemical Analyzers are all made of immunoturbidimetry currently on the market, according to the absorption spectrum of substance come
Carry out qualitative and quantitative analysis.
Reaction tray component is one of Biochemical Analyzer core component, is used to carry reaction cup, and reaction cup is transmitted to light
Electric data collecting position reacts sample in thermostat with reagent, measures the absorbance of reaction solution.
There are two types of the Biochemical Analyzers for measuring biochemical project using immunoturbidimetry currently on the market, first is that external centrifugation
Testing liquid is placed in centrifuge tube by mode, is then put on centrifuge and is centrifuged, by the sample after centrifugation after the completion of centrifugation
Clear liquid is placed on routine biochemistry analyzer and is detected.Another way is filtered liquid sample using ultrafiltration membrane, then
Sample clear liquid after the completion of filtering is put on routine biochemistry analyzer and is detected.
Processing to the external centrifugation of primary liquid sample needs that manually the sample clear liquid shifting after centrifugation is put into biochemical instruments,
This process is very careful, if container collision or shake when movement, placement, will lead to the good sample clear liquid of centrifugation again
Become muddy, influences test result.Liquid sample is filtered using ultrafiltration membrane, increases filtration step, and is whether artificial
Filtering or instrument filtering, are required to introduce new consumptive material, increase testing cost；Especially filter process has pollution risk,
It easily causes visible component to be mixed into sample liquid, influences test result.
In short, existing liquid sample processing method increases operating procedure, the workload of inspector is increased, is made complete
The degree of automation of automatic biochemistry analyzer declines, and also makes the reduction of its detection efficiency.
Summary of the invention
In view of the deficiencies of the prior art, it is an object of the present invention to provide a kind of automatic clinical chemistry analyzer reaction tray, reactions
Disk cover component is equipped with n movable cup bowl assembly and m fixed cup bowl assembly.N≤m, n, m are even number.Reaction tray cap assemblies have N number of
Cup slot is divided into X cup slot of mounting bracket and Y cup slot of movable bracket.Each fixed cup bowl assembly includes mounting bracket and its
On the cup slots that are matched with reaction cup of X/m.Each activity cup bowl assembly include movable bracket and Y/n thereon it is a with react
The cup slot that cup matches.The fixed shaft in movable bracket inside top edge is inserted in the shaft hole for being fixed on the shaft seat of reaction tray
It is interior.When reaction tray cap assemblies high-speed rotation, movable bracket is acted on by centrifugal force, is rotated along shaft, and movable bracket bottom is to anti-
Outer top should be coiled to dig, the sample liquid in the reaction cup of movable bracket cup slot is centrifuged.
It is a further object of the present invention to provide a kind of application methods of automatic clinical chemistry analyzer reaction tray, first will be wait be centrifuged
Sample liquid be added in the reaction cup of movable bracket cup slot, the sample-adding amount of each reaction cup is equal, make Y movable bracket cup slot still with
Reaction disk center is centrosymmetric, and guarantees the dynamic balancing of reaction tray cap assemblies when rotation.The present invention solve fluid sample from
The heart handles problem；Sample liquid is handled without using other centrifugal apparatuses, reduces needed for test manually, improves testing efficiency, is realized true
Positive full-automatic biochemical analysis.
A kind of automatic clinical chemistry analyzer reaction tray provided by the invention, including reaction tray cap assemblies, main shaft and motor, electricity
Machine is fixedly installed on the Biochemical Analyzer chassis below reaction tray cap assemblies, and main shaft is rotationally vertically arranged to biochemical analysis
Instrument rack.Motor output shaft is connected through shaft coupling with main shaft, and the reaction disk cover center of reaction tray cap assemblies is installed on main shaft top
Portion, reaction tray cap surface are level.The reaction tray cap assemblies include the N for reacting disk cover, being distributed in reaction disk cover circumferential outer edge
A identical rectangular cup slot of shapes and sizes and N number of same reaction cup with the cooperation of cup slot, 16≤N≤512.
It reacts disk cover and is furnished with m fixed cup bowl assembly, m is even number, 2≤m≤20.Disk cover is reacted equipped with n movable cup slot
Component, n are even number, n≤m.N number of glass of slot of the reaction tray cap assemblies is divided into the X cup slot and movable cup of fixed cup bowl assembly
Y cup slot of bowl assembly, X are the multiple of m, and Y is the multiple of n, and Y is less than or equal to X.N movable cup bowl assembly is by m fixed cup
Bowl assembly separates, and is centrosymmetric distribution with reacting disk cover center.
The fixed cup bowl assembly is to fix relative to reaction disk cover, and each fixed cup bowl assembly includes mounting bracket and its
On the cup slots that are matched with reaction cup of X/m.Mounting bracket is and the arc-shaped bracket that reacts disk cover and match, mounting bracket top
Reaction disk cover outer rim is fixed on the inside of portion.Reaction cup is inserted in mounting bracket cup slot, the center line of reaction cup with react disk cover
Disk is vertical.
The activity cup bowl assembly includes movable bracket and a cup slots matched with reaction cup of Y/n thereon.The work
Dynamic bracket be with the arc-shaped bracket for reacting disk cover and matching, 1~3 shaft is fixed at movable bracket inside top edge.
On the same movable bracket midpoint of 1 shaft or the midpoint of multiple shaft lines with react disk cover center
Line perpendicular to the shaft or multiple shafts；The installation site of shaft is vertically put down with the center at movable bracket inside top edge
Facet is symmetrical.
The shaft seat matched with shaft is fixed at the reaction disk cover edge, has shaft hole on shaft seat, shaft is rotatable
Ground is inserted in the shaft hole of shaft seat, and movable bracket is flexibly connected through shaft and shaft seat with disk cover outer rim is reacted.Work as reaction tray
When cap assemblies are static or slowly run, the reaction cup center line being inserted in movable bracket cup slot is vertical with reaction tray disk, activity
The reaction cup in reaction cup and mounting bracket cup slot in bracket cup slot is in identical level height.When reaction tray cap assemblies are high
When speed rotation, the movable bracket along shaft high-speed rotation is acted on by centrifugal force, and movable bracket bottom is turned over to the reaction outside upper side of disk cover
It rises, the angle of cut of glass slot and reaction cup center line and horizontal plane is 120 °~140 °.
The speed of the reaction tray cap assemblies to slowly run is equal to or less than 20r/min, the reaction tray cap assemblies
The speed of high-speed rotation is greater than or equal to 1200r/min.
There are the groove of 1~3 with shaft seat cooperation in the reaction disk cover edge, and shaft seat is fixedly installed in groove.
The motor is servo motor.
The cup slot of the movable bracket and the cup slot of mounting bracket are identical, and cup slot radical length is bigger than reaction cup length by 1~
2mm, installation pre-tightens elastic slice on cup slot lateral wall, and the top for pre-tightening elastic slice is fixing piece, connects fork-shaped elastic slice under fixing piece.Elastic slice connects
It is continuous bending twice, side view in Jiong shape as fixing piece, on cup slot lateral wall top, the fork-shaped elastic slice of lower section protrudes into fixing piece jam
Cup slot inner cavity.Reaction cup is inserted into the fork-shaped elastic slice that compressing after cup slot pre-tightens elastic slice lower part, and it is inner that elastic force pushes reaction cup to glass slot
The cell wall of side positions.
The movable bracket and mounting bracket outside top, cup slot lateral wall form step lower than edge on cup slot, arc
Briquetting is fixed on the step, and briquetting is pushed down at the top of the preload elastic slice fixing piece Jiong shape in cup cell wall top, to prevent taking out reaction
Elastic slice is pre-tightened when cup and is carried over falls off.
Arc-shaped clump weight is fixedly installed in the movable bracket bottom inside, with the weight of adjusting activity cup bowl assembly
The heart, thus the angle that movable bracket is dug when adjusting reaction tray cap assemblies high-speed rotation.
The convex edge that the oriented movable bracket in the reaction disk cover edge stretches out, the oriented reaction disk cover in the top inner edge of movable bracket
Upper eaves outstanding, when reaction tray cap assemblies are static or slowly run, the upper eaves of movable bracket is ridden on the convex edge of reaction disk cover, on
The lower surface of eaves is bonded with the upper surface of convex edge, so that the reaction cup in movable bracket is static or slowly run in reaction tray component
When with mounting bracket in reaction cup be in same level height, in order to carry out biochemical test.
The automatic clinical chemistry analyzer reaction tray further include heating coil assembly, the heating coil assembly include heating mantles,
Ring and temperature sensor, heating mantles coating reaction disk cover component are heated, heating mantles are the cylinder that internal diameter is greater than reaction disk cover, cylinder
Bottom is connected to a fixed by support column and reaction tray base plate, and heating mantles are coaxial with main shaft.Barrel top is higher than the reaction
3~5mm of maximum height after activity reaction cup assembly is dug when disk cover component high speed rotation.In the heating ring of cylinder inner wall installation
There is uniformly distributed heater strip, the electromagnetic switch of heater strip and control centre's connection of Biochemical Analyzer are controlled by it and are switched on or switched off,
Temperature sensor is installed in heating mantles, and signal wire accesses the input terminal of Biochemical Analyzer.Biochemical Analyzer control centre root
Heating wire switch connection or disconnection are controlled according to the temperature signal of temperature sensor, controls the temperature inside heating mantles, so that reaction
Proper temperature is in when each reaction cup test of disk cover component.
A kind of application method of automatic clinical chemistry analyzer reaction tray of the invention includes following key step:
I, fluid sample to be centrifuged is added
Sample liquid to be centrifuged is added to the reaction cup of y cup slot of movable bracket by biochemical instruments control centre control sample arm
Interior, y≤Y, y are the multiple of n, and the sample-adding amount of y reaction cup is equal, make Y cup slot of movable bracket to react during disk cover center is in
The heart is symmetrical, guarantees the dynamic balancing of reaction tray cap assemblies when rotation.
II, it is centrifuged
Control centre control motor driven main axis, drive reaction tray cap assemblies high-speed rotation, movable bracket by from
Mental and physical efforts, bottom are dug to the reaction outside upper side of disk cover, and the angle of cut of interior reaction cup center line and horizontal plane is 120 °~140 °.
Suffered centrifugal force F depends on the amount m of radius of turn r, rotational speed omega and fluid sample
F=m ω2r
To reach good centrifugal effect, reaction tray cap assemblies revolving speed is 1200r/min~1800r/min, duration
It is 3~8 minutes.
III, divide sample
After motor power-off, static 0.5~3 minute, biochemical instruments control centre control motor made reaction tray cap assemblies low speed rotation
It is dynamic, control sample arm the upper layer sample clear liquid after centrifugation in y reaction cup is distributed to according to test request be ready for it is each
In the reaction cup of the fixed cup bowl assembly of test item；
IV, it tests
The control centre of biochemical instruments routinely controls reaction tray cap assemblies and sample arm according to test request, successively addition examination
Agent, stirring and reaction are successively sent to detection hole location after reaction needed for completing and are detected.
Compared with prior art, a kind of automatic clinical chemistry analyzer reaction tray of the present invention and its advantages of application method
In: 1, movable bracket reaction tray cap assemblies on can in motor high-speed rotation upwards dig, and make reaction tray cap assemblies and centrifugation
Machine is combined into one, and solves the problems, such as the centrifugal treating of fluid sample；2, sample liquid is handled without using other centrifugal apparatuses, reduces and surveys
It is artificial needed for examination, testing efficiency is improved, realizes real full-automatic biochemical analysis；3, reaction tray spindle motor directly drives its height
Speed rotation, maximum speed fully meet centrifugal force needed for sample liquid up to 6000r/min, and structure is simple, easy for installation；And it moves
Steadily, without obvious noise.
Detailed description of the invention
Fig. 1 is the overall structure front section view of this automatic clinical chemistry analyzer reaction tray embodiment；
Overall structure front cross-sectional when Fig. 2 is this automatic clinical chemistry analyzer reaction tray embodiment main shaft high speed rotation
Figure；
Fig. 3 is reaction tray cap assemblies schematic diagram in Fig. 1；
Fig. 4 is movable cup bowl assembly schematic diagram in Fig. 1；
Fig. 5 is the top view of reaction tray cap assemblies in Fig. 1；
Fig. 6 is the enlarged diagram of part A in Fig. 5；
Fig. 7 is that the movable cup bowl assembly of this automatic clinical chemistry analyzer reaction tray embodiment is illustrated with disk cover relationship is reacted
Figure；
Fig. 8 is the enlarged diagram of part B in Fig. 7；
Fig. 9 is that the reaction cup of automatic clinical chemistry analyzer reaction tray embodiment pre-tightens elastic slice schematic diagram.
Figure label are as follows:
1, reaction tray cap assemblies, 11, reaction disk cover, 111, shaft seat, 12, fixed cup bowl assembly, 13, movable cup slot group
Part, 131, movable bracket, 132, shaft, 133, briquetting, 134, clump weight, 2, main shaft, 3, heating coil assembly, 4, heating coil support
Column, 5, reaction tray bottom plate, 6, motor, 7, cup slot, 71, preload elastic slice, 8, reaction cup
Specific embodiment
To further illustrate specific design and structure of the invention, with reference to embodiments and attached drawing is described in detail.
Automatic clinical chemistry analyzer reaction tray embodiment
The overall structure of this automatic clinical chemistry analyzer reaction tray embodiment is as depicted in figs. 1 and 2, including reaction disk cover group
Part 1, main shaft 2, heating coil assembly 3 and motor 6, this example motor 6 are servo motor.Motor 6 is fixedly installed in reaction tray cap assemblies 1
On the Biochemical Analyzer chassis of lower section, main shaft 2 is rotationally vertically arranged to Biochemical Analyzer rack.6 output shaft of motor is through joining
Axis device is connected with main shaft 2, and 11 center of reaction disk cover of reaction tray cap assemblies 1 is installed on 2 top of main shaft, reacts 11 surface of disk cover
For level.This example reaction tray cap assemblies 1 include reaction disk cover 11, be distributed in reaction 11 circumferential outer edge of disk cover 120 shapes and
The identical reaction cup 8 that the identical rectangular cup slot 7 and 120 of size cooperates with cup slot.
As shown in figure 3, this example reaction disk cover 11 is furnished with 4 fixed cup bowl assemblies 12, it is solid relative to reaction disk cover 11
Fixed, this example reacts disk cover 11 equipped with 2 movable cup bowl assemblies 13.2 movable cup bowl assemblies 13 by 2 fixed cup bowl assemblies 12 every
It opens, the distribution sequence on reaction 11 circumference of disk cover is " movable cup bowl assembly 13 ", 2 " fixed cup bowl assembly 12 ", " movable cups
Bowl assembly 13 ", 2 " fixed cup bowl assembly 12 ", each cup bowl assembly are centrosymmetric distribution with reacting 11 center of disk cover.
The 20 cup slots 7 that with reaction cup 8 match of each fixed cup bowl assembly 112 including mounting bracket and thereon.Gu
Determine the arc-shaped bracket that bracket is with react disk cover 11 and match, the located pin of mounting bracket inside top, which is fixed on, reacts disk cover 11
Outer rim.Reaction cup 8 is inserted in the cup slot of mounting bracket, and the center line of reaction cup 8 is vertical with the disk for reacting disk cover 11.
The 20 cup slots 7 matched with reaction cup 8 of each activity cup bowl assembly 13 including movable bracket 131 and thereon.
As shown in Figs. 4-6, the movable bracket 131 of each movable cup bowl assembly 13 is and the arc-shaped bracket that react disk cover 11 and match, work
2 shafts 132 are fixed at dynamic 131 inside top edge of bracket.
On the same movable bracket 131 midpoint of 2 shaft lines with react the line at disk cover center perpendicular to turning
Axis；It is symmetrical that the installation site of 2 shafts 132, which vertically divides face equally with the center at 131 inside top edge of movable bracket,；
The fixed shaft seat 111 matched with the shaft 132 on movable bracket 131 in edge of this example reaction disk cover 11, turns
There is shaft hole on axle bed 111, shaft 132 is rotationally inserted in the shaft hole of shaft seat 111, and movable bracket 131 is through shaft 132
It is flexibly connected with shaft seat 111 with 11 outer rim of disk cover is reacted.When reaction tray cap assemblies 1 are static or slowly run, movable bracket
Cup slot and its interior reaction cup center line with react that 11 disk of disk cover is vertical, the reaction cup in 131 glasss of slots of movable bracket and solid
The reaction cup determined in bracket cup slot is in identical level height.When reaction tray 1 high-speed rotation of cap assemblies, movable bracket 131
Also high-speed rotation, under the action of the centrifugal force, movable bracket rotate up and out along shaft 132, and 131 bottom of movable bracket is to anti-
Answer the outer top of disk cover 11 to dig, in cup slot and reaction cup center line and horizontal interfacial angle be 120 °~140 °.
The speed of the reaction tray cap assemblies 1 to slowly run is equal to or less than 20r/min, the reaction tray cap assemblies 1
High-speed rotation speed be greater than or equal to 1200r/min.
There are 2 grooves cooperated with shaft seat 111 at this example reaction 11 edge of disk cover, and shaft seat 111 is fixedly installed in groove
It is interior.
This example movable bracket is identical with the cup slot of mounting bracket, as shown in figure 9, the radical length of cup slot 7 is longer than reaction cup 8
Big 1~2mm is spent, installation pre-tightens elastic slice 71 on 7 lateral wall of cup slot, and the top for pre-tightening elastic slice 71 is fixing piece 711, fixing piece 711
Lower even fork-shaped elastic slice 712.Elastic slice continuously bend twice, side view in Jiong shape as fixing piece 711,711 jam of fixing piece is in cup slot 7
On lateral wall top, the fork-shaped elastic slice 712 of lower section protrudes into 7 inner cavity of glass slot.Compressing pre-tightens under elastic slice 71 after reaction cup 8 is inserted into cup slot 7
The fork-shaped elastic slice in portion, elastic force are pushed reaction cup 8 cell wall of glass slot 7 in the inner part to and are positioned.
The movable bracket 131 and mounting bracket outside top, 7 lateral wall of cup slot form step lower than edge on cup slot 71,
The briquetting 133 of arc is fixed on the step, and briquetting 133 pushes down 71 fixing piece of preload elastic slice, the 711 Jiong shape in 7 wall top of cup slot
Top, preload elastic slice 71, which will not be carried over, when taking out reaction cup 8 falls off.
Arc-shaped clump weight 134 is fixedly installed in 131 bottom inside of movable bracket, with adjusting activity cup bowl assembly
13 center of gravity, thus the angle that movable bracket 131 is dug when adjusting reaction tray 1 high-speed rotation of cap assemblies.
The convex edge that the oriented movable bracket 131 in reaction 11 edge of disk cover stretches out, the top inner edge of movable bracket 131 are oriented
The upper eaves outstanding of disk cover 11 is reacted, when reaction tray cap assemblies 1 are static or slowly run, the upper eaves of movable bracket 131 rides over reaction
On the convex edge of disk cover 1, the lower surface of upper eaves is bonded with the upper surface of convex edge, so that the reaction cup 8 in movable bracket is in reaction tray
It is in same level height with the reaction cup 8 in mounting bracket when cap assemblies 1 are static or slowly run, is convenient for biochemical survey
Examination.
The heating coil assembly of this example automatic clinical chemistry analyzer reaction tray includes heating mantles, heats ring and temperature sensor,
Heating mantles coating reaction disk cover component 1, heating mantles are the cylinder that internal diameter is greater than reaction disk cover, and bottom of cylinder is supported by heating coil
Column 4 is connected to a fixed with reaction tray base plate 5, and heating mantles and main shaft 2 are coaxial.Barrel top is higher than the reaction tray cap assemblies 1
3~5mm of maximum height after activity cup bowl assembly 13 is dug when high speed rotation.Have in the heating ring of heating mantles cylinder inner wall installation
Uniformly distributed heater strip, the electromagnetic switch of heater strip and control centre's connection of Biochemical Analyzer are controlled by it and are switched on or switched off, temperature
Degree sensor is installed in heating mantles, and signal wire accesses the input terminal of Biochemical Analyzer.Biochemical Analyzer control centre according to
The temperature signal control heating wire switch connection of temperature sensor or disconnection, control the temperature inside heating mantles, so that reaction tray
Proper temperature is in when each reaction cup 8 of cap assemblies 1 is tested.
The application method embodiment of this automatic clinical chemistry analyzer reaction tray, it is anti-using above-mentioned automatic clinical chemistry analyzer
Embodiment 1 or 2, including following key step should be coiled:
I, fluid sample to be centrifuged is added
Biochemical instruments control centre control sample arm by sample liquid to be centrifuged be added to movable bracket 131 y cup slot it is anti-
It answers in cup 8, y≤Y, y is the multiple of n, and the sample-adding amount of y reaction cup 8 is equal, makes movable bracket 131 to react 11 center of disk cover
It is centrosymmetric, guarantees the dynamic balancing of reaction tray cap assemblies 1 when rotation.
II, it is centrifuged
Control centre controls the rotation of 6 driving spindle 2 of motor, drives 1 high-speed rotation of reaction tray cap assemblies, movable bracket 131
By centrifugal force, bottom is dug top to outside reaction disk cover 11, and the angle of cut of interior 8 center line of reaction cup and horizontal plane is 120 °~
140°。
Suffered centrifugal force F depends on the amount m of radius of turn r, rotational speed omega and fluid sample
F=m ω2r
To reach good centrifugal effect, 1 revolving speed of reaction tray cap assemblies is 1200r/min~1800r/min, duration
It is 3~8 minutes.
III, divide sample
After motor 6 powers off, static 0.5~3 minute, biochemical instruments control centre control motor 6 made 1 low speed of reaction tray cap assemblies
Upper layer sample clear liquid after being centrifuged in y reaction cup 8 is distributed to according to test request and is ready for respectively by rotation, control sample arm
In the reaction cup 8 of the fixed cup bowl assembly 12 of a test item；
IV, it tests
The control centre of biochemical instruments routinely controls reaction tray cap assemblies 1 and sample arm according to test request, successively adds
Reagent, stirring and reaction are successively sent to detection hole location after reaction needed for completing and are detected.
Above-described embodiment is only further described the purpose of the present invention, technical scheme and beneficial effects specific
A example, present invention is not limited to this.All any modifications made within the scope of disclosure of the invention, change equivalent replacement
Into etc., it is all included in the scope of protection of the present invention.
Claims (10)
1. a kind of automatic clinical chemistry analyzer reaction tray, including reaction tray cap assemblies (1), main shaft (2) and motor (6), motor (6)
It is fixedly installed on the Biochemical Analyzer chassis below reaction tray cap assemblies (1), main shaft (2) is rotationally vertically arranged to biochemistry
Analyzer rack；Motor (6) output shaft is connected through shaft coupling with main shaft (2), the reaction disk cover (11) of reaction tray cap assemblies (1)
Center is installed at the top of main shaft (2), and reaction disk cover (11) surface is level；The reaction tray cap assemblies (1) include reaction disk cover
(11), the identical rectangular cup slot (7) of N number of shapes and sizes for reacting disk cover (11) circumferential outer edge and N number of and cup slot (7) are distributed in
The same reaction cup (8) of cooperation, 16≤N≤512；It is characterized by:
The reaction disk cover (11) is furnished with m fixed cup bowl assembly (12), and m is even number, 2≤m≤20；Reaction disk cover (11) is furnished with
N movable cup bowl assembly (13), n is even number, n≤m；N number of glass of slot (7) of the reaction tray cap assemblies (1) is divided into fixed cup slot
Y cup slot of X cup slot of component (12) and movable cup bowl assembly (13), X are the multiple of m, and Y is the multiple of n, and Y is less than or waits
In X；N movable cup bowl assembly (13) is separated by m fixed cup bowl assembly (12), and to react disk cover (11) center in center pair
Claim distribution；
The fixed cup bowl assembly (12) is to fix relative to reaction disk cover (11), and each fixed cup bowl assembly (12) includes fixing
Bracket and the X/m thereon cup slots (7) matched with reaction cup (8)；Mounting bracket is matched with disk cover (11) is reacted
Arc-shaped bracket, mounting bracket inside top are fixed on reaction disk cover (11) outer rim；Reaction cup (8) is inserted in the cup slot of mounting bracket
Interior, the center line of reaction cup (8) is vertical with the disk for reacting disk cover (11)；
The activity cup bowl assembly (13) includes movable bracket (131) and a cup slots matched with reaction cup (8) of Y/n thereon
(7)；
The movable bracket (131) of each activity cup bowl assembly (13) be with the arc-shaped bracket that react disk cover (11) and match, it is movable
1~3 shaft (132) is fixed at bracket (131) inside top edge, each shaft (132) centerline in react disk cover (11)
On the parallel same straight line in surface, the fixed shaft seat (111) matched with shaft (132) in reaction disk cover (11) edge, shaft
There is shaft hole on seat (111), shaft (132) is rotationally inserted in the shaft hole of shaft seat (111), movable bracket (131) warp
Shaft (132) and shaft seat (111) are flexibly connected with disk cover (11) outer rim is reacted；When reaction tray cap assemblies (1) are static or low speed
When rotation, reaction cup (8) center line being inserted in the cup slot (7) of movable bracket (131) is vertical with reaction tray disk (11), activity
Reaction cup (8) in the cup slot (7) of bracket (131) and the reaction cup (8) in the cup slot of mounting bracket are in identical horizontal high
Degree；When reaction tray cap assemblies (1) high-speed rotation, movable bracket (131) is acted on by centrifugal force, is rotated along shaft (132), activity
To reaction disk cover (11), top is dug outside for bracket (131) bottom, in reaction cup (8) center line and the angle of cut of horizontal plane be
120 °~140 °；
The speed of the reaction tray cap assemblies (1) to slowly run is equal to or less than 20r/min, the reaction tray cap assemblies (1)
High-speed rotation speed be more than or equal to 1200r/min.
2. automatic clinical chemistry analyzer reaction tray according to claim 1, it is characterised in that:
The midpoint of the midpoint of upper 1 shaft (132) of same movable bracket (131) or multiple shafts (132) line and anti-
Answer the line at disk cover (11) center perpendicular to the shaft (132) or multiple shafts (132)；The installation site of shaft (132) is with work
It is symmetrical that face is vertically divided at the center at dynamic bracket (131) inside top edge, which equally,.
3. automatic clinical chemistry analyzer reaction tray according to claim 1, it is characterised in that:
The motor (6) is servo motor.
4. automatic clinical chemistry analyzer reaction tray according to claim 1, it is characterised in that:
There are the groove of 1~3 with shaft seat (111) cooperation in described reaction disk cover (11) edge, and shaft seat (111) is fixedly installed in
In groove.
5. automatic clinical chemistry analyzer reaction tray according to any one of claim 1 to 4, it is characterised in that:
The radical length of the cup slot (7) of the cup slot (7) and mounting bracket of the movable bracket (131) is bigger by 1 than reaction cup (8) length
~2mm, installation pre-tightens elastic slice (71) on cup slot (7) lateral wall, and the top for pre-tightening elastic slice (71) is fixing piece, connects fork under fixing piece
Shape elastic slice；Elastic slice continuously bend twice, side view in Jiong shape as fixing piece, fixing piece jam on cup slot (7) lateral wall top, under
The fork-shaped elastic slice of side protrudes into a glass slot (7) inner cavity；Reaction cup (8) is inserted into cup slot (7) and oppresses the fork-shaped for pre-tightening elastic slice (71) lower part afterwards
Elastic slice, elastic force are pushed reaction cup (8) cell wall of a glass slot (7) in the inner part to and are positioned.
6. automatic clinical chemistry analyzer reaction tray according to claim 5, it is characterised in that:
The movable bracket (131) and mounting bracket outside top, i.e. cup slot (7) lateral wall form platform lower than edge on cup slot (7)
The briquetting (133) of rank, arc is fixed on the step, and it is solid that briquetting (133) pushes down the preload elastic slice (71) in cup slot (7) wall top
Determine at the top of part Jiong shape.
7. automatic clinical chemistry analyzer reaction tray according to any one of claim 1 to 4, it is characterised in that:
Arc-shaped clump weight (134) is fixedly installed in the movable bracket (131) bottom inside.
8. automatic clinical chemistry analyzer reaction tray according to any one of claim 1 to 4, it is characterised in that:
The convex edge that the reaction oriented movable bracket in disk cover (11) edge (131) is stretched out, the top inner edge of movable bracket (131) has
To reaction disk cover (11) upper eaves outstanding, when reaction disk cover (11) is static or slowly runs, the upper eaves of movable bracket (131) is ridden over
On the convex edge for reacting disk cover (11), the lower surface of upper eaves is bonded with the upper surface of convex edge, makes the reaction cup in movable bracket (131)
(8) static or be in same level height with the reaction cup (8) in mounting bracket when slowly running in reaction tray component (1).
9. automatic clinical chemistry analyzer reaction tray according to any one of claim 1 to 4, it is characterised in that:
The automatic clinical chemistry analyzer reaction tray further includes heating coil assembly (3), and the heating coil assembly (3) includes heating
Cover, heating ring and temperature sensor, heating mantles coating reaction disk component (1), heating mantles are that internal diameter is greater than reaction disk cover (11)
Cylinder, bottom of cylinder are connected to a fixed by heating coil support column (4) with the bottom plate for reacting disk cover (11), heating mantles and main shaft
(2) coaxial；After the reaction cup (8) of movable bracket (131) is dug when barrel top is higher than described reaction disk cover (11) high speed rotation
3~5mm of maximum height；There are uniformly distributed heater strip, the electromagnetic switch and biochemistry of heater strip in the heating ring of cylinder inner wall installation
Control centre's connection of analyzer, which is controlled by it, to be switched on or switched off, and temperature sensor is installed in heating mantles, signal wire access
The input terminal of Biochemical Analyzer.
10. the application method of automatic clinical chemistry analyzer reaction tray according to any one of claim 1 to 4, feature
It is to include following key step:
I, fluid sample to be centrifuged is added
Sample liquid to be centrifuged is added to the reaction of y cup slot of movable bracket (131) by biochemical instruments control centre control sample arm
In cup (8), y≤Y, y are the multiple of n, and the sample-adding amount of y reaction cup (8) is equal, makes Y cup slot of movable bracket (131) with anti-
It answers disk cover (11) center to be centrosymmetric, guarantees the dynamic balancing of reaction tray cap assemblies (1) when rotation；
II, it is centrifuged
Control centre controls motor (6) driving spindle (2) rotation, drives reaction tray cap assemblies (1) high-speed rotation, movable bracket
(131) by centrifugal force, bottom is dug to the reaction outside upper side of disk cover, and the angle of cut of interior reaction cup (8) center line and horizontal plane is
120 °~140 °；
Reaction disk cover (11) revolving speed is 1200r/min~1800r/min, and the duration is 3~8 minutes；
III, divide sample
After motor (6) power-off, static 0.5~3 minute, biochemical instruments control centre control motor (6) made to react disk cover (11) low speed
Upper layer sample clear liquid after centrifugation in y reaction cup (8) is distributed to according to test request and is ready for by rotation, control sample arm
In the reaction cup (8) of the fixed cup bowl assembly (13) of each test item；
IV, it tests
The control centre of biochemical instruments routinely controls reaction tray cap assemblies (1) and sample arm according to test request, successively addition examination
Agent, stirring and reaction are successively sent to detection hole location after reaction needed for completing and are detected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811035109.3A CN109188007B (en) | 2018-09-06 | 2018-09-06 | Reaction disc of full-automatic biochemical analyzer and use method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811035109.3A CN109188007B (en) | 2018-09-06 | 2018-09-06 | Reaction disc of full-automatic biochemical analyzer and use method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109188007A true CN109188007A (en) | 2019-01-11 |
| CN109188007B CN109188007B (en) | 2022-04-12 |
Family
ID=64914881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811035109.3A Active CN109188007B (en) | 2018-09-06 | 2018-09-06 | Reaction disc of full-automatic biochemical analyzer and use method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109188007B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112221724A (en) * | 2020-09-01 | 2021-01-15 | 刘勇 | Automatic blood separation system and method |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3865274A (en) * | 1970-04-29 | 1975-02-11 | Becton Dickinson Co | Liquid dispensing apparatus |
| US20050026765A1 (en) * | 2003-07-29 | 2005-02-03 | Diagyr | Process to balance a rotatable plate of a centrifuge and centrifuge using the process |
| CN1890569A (en) * | 2003-12-08 | 2007-01-03 | 和光纯药工业株式会社 | Automatic analyzer-use reaction disc and separating cell |
| CN107621444A (en) * | 2017-08-30 | 2018-01-23 | 桂林优利特医疗电子有限公司 | A kind of free-standing reaction cup fixed structure of Biochemical Analyzer |
| CN108061809A (en) * | 2017-11-27 | 2018-05-22 | 桂林优利特医疗电子有限公司 | Biochemical instruments react cup holding rack and reaction tray movement accuracy-control system |
-
2018
- 2018-09-06 CN CN201811035109.3A patent/CN109188007B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3865274A (en) * | 1970-04-29 | 1975-02-11 | Becton Dickinson Co | Liquid dispensing apparatus |
| US20050026765A1 (en) * | 2003-07-29 | 2005-02-03 | Diagyr | Process to balance a rotatable plate of a centrifuge and centrifuge using the process |
| CN1890569A (en) * | 2003-12-08 | 2007-01-03 | 和光纯药工业株式会社 | Automatic analyzer-use reaction disc and separating cell |
| CN107621444A (en) * | 2017-08-30 | 2018-01-23 | 桂林优利特医疗电子有限公司 | A kind of free-standing reaction cup fixed structure of Biochemical Analyzer |
| CN108061809A (en) * | 2017-11-27 | 2018-05-22 | 桂林优利特医疗电子有限公司 | Biochemical instruments react cup holding rack and reaction tray movement accuracy-control system |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112221724A (en) * | 2020-09-01 | 2021-01-15 | 刘勇 | Automatic blood separation system and method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109188007B (en) | 2022-04-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4360360A (en) | Centrifugal analyzer | |
| JP5290432B2 (en) | Apparatus and analysis system for agglutination inspection | |
| CN102147405B (en) | Fully automatic biochemical immune analyzer | |
| JP3390001B2 (en) | Multi-analyte test vehicle | |
| CN109633188B (en) | Full-automatic multifunctional biochemical analyzer and application method thereof | |
| CN108120840A (en) | Full-automatic immunoblotting assay instrument | |
| JPH07505473A (en) | Automatic continuous random access analysis system and its components | |
| CN103969459A (en) | Full-automatic biochemical analysis method | |
| CN104034908A (en) | Novel full-automatic biochemical analyzer | |
| JP7361492B2 (en) | Laboratory systems and methods for separating interfering substances contained in test samples | |
| CN109188007A (en) | A kind of automatic clinical chemistry analyzer reaction tray and its application method | |
| CN112156747A (en) | Reaction cup and reaction cup mixing device | |
| CN105880041A (en) | Mechanism for simultaneously realizing functions of blending and centrifuging reagent | |
| CN109765391B (en) | Multi-index detection centrifugal test strip chip | |
| CN209784380U (en) | Full-automatic multifunctional biochemical analyzer | |
| EP2372366B1 (en) | Analysis station with incubation system | |
| CN213824849U (en) | Reaction cup mixing device | |
| EP0749572B1 (en) | Test tube and apparatus for carrying out immunohaematological analysis of blood and other biological liquids | |
| EP3877088A1 (en) | Apparatus and method for mixing fluid or media by vibrating a pipette using nonconcentric masses | |
| CN220386835U (en) | Test tube centrifuge | |
| CN214225193U (en) | Shake even device and protein analyzer | |
| CN217725326U (en) | Even mechanism is shaken in kit storage storehouse | |
| US11951469B2 (en) | Device for storing reagent containers on several planes | |
| CN220047883U (en) | Integrated reaction cup mixing device | |
| CN210294269U (en) | Vibration-proof structure of biochemical analyzer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |