CN109171661A - Fluoroscopic visualization checks system excitation light source - Google Patents

Fluoroscopic visualization checks system excitation light source Download PDF

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Publication number
CN109171661A
CN109171661A CN201811182748.2A CN201811182748A CN109171661A CN 109171661 A CN109171661 A CN 109171661A CN 201811182748 A CN201811182748 A CN 201811182748A CN 109171661 A CN109171661 A CN 109171661A
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CN
China
Prior art keywords
light source
system excitation
excitation light
visible light
fluoroscopic visualization
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CN201811182748.2A
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Chinese (zh)
Inventor
蔡惠明
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Nanjing Lifenergy Pharmaceutival Industry Co ltd
Nanjing Connaught Medical Instrument Co Ltd
Original Assignee
Nanjing Lifenergy Pharmaceutival Industry Co ltd
Nanjing Connaught Medical Instrument Co Ltd
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Priority to CN201811182748.2A priority Critical patent/CN109171661A/en
Publication of CN109171661A publication Critical patent/CN109171661A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The present invention relates to Imaging-PAM fields, are related to fluoroscopic visualization and check system excitation light source.Fluoroscopic visualization checks that system excitation light source includes shell, light source bracket, laser source, visible light source and observation channel;Observation is provided with light collector in channel.When in use, shell is directly contacted with body tissue surface, the exciting light of body tissue surface reflection can be blocked by device itself in this way, and the exciting light for penetrating body tissue is irradiated to fluorescence caused by ICG, but it can be penetrated in channel from device center, and received by light collector, influence of a large amount of reflected excitation lights to picture is avoided, image effect is enhanced.Light collector can receive the visible light of visible light source sending, in post-processing, can by after fluorescence image processing with the color image of specific color addition to visible light on, allow surgical staff to see the entirety of field of operation simultaneously and the case where lymph body therein, surgical staff is facilitated to use.

Description

Fluoroscopic visualization checks system excitation light source
Technical field
The present invention relates to Imaging-PAM fields, check system excitation light source in particular to fluoroscopic visualization.
Background technique
Sentinel lymph node is the special lymph node in primary tumo(u)r drainage regional lymph nodes, is that lymph node occurs for primary tumo(u)r Shift first necessary lymph node.The clinical application of sentinel lymph node biopsy makes the mammary gland that axillary gland does not shift Carninomatosis people avoids axillary lymph node dissection, so as to avoid corresponding postoperative complication such as upper limb lymphedema etc., greatly mentions The high quality of life of patient, therefore be concerned by people.
There are three types of methods at present to detect sentinel lymph node: blue dyes method, the method is more traditional, uses the indigo plants such as methylene blue Color stain, effect is bad, and doctor is needed to have very long learning curve.(2) nucleic probe method, because being related to radioactive element, There is certain radiation effects to human body, can cause environmental pollution simultaneously, use is also more troublesome, does not promote in clinic It opens, and device systems are more expensive.(3) fluorescent penetrant method, this is a kind of newest detection method quickly, safe, uses fluorescence Detection device watches indocyanine green (ICG) fluorescence, can be quickly found out sentinel lymph node, and be imaged over the display.
ICG vein or be subcutaneously injected into vivo after, rapidly and protein combine, ICG by 700-800nm exciting light photograph Penetrate the fluorescence for generating 800-900nm.Because ICG fluorescence belongs near infrared light, human eye can not be observed directly, so needing fluorescence Detection device is observed.Therefore fluorescent penetrant method image quality directly affects the judgement and operation effect of sentinel lymph node position Fruit.
In sentinel lymph node biopsy operation, the lymph node position of most of patients is relatively deep, in noninvasive situation, uses Conventional fluorescent detection device is difficult to observe the specific location of lymph node.It causes repeatedly to observe, and estimates lymph node position, make At the cumbersome of operation and increase the fault possibility estimated.
Therefore it provides a kind of fluoroscopic visualization easy to use checks that system excitation light source becomes those skilled in the art and wanted The important technological problems of solution.
Summary of the invention
The purpose of the present invention is to provide a kind of fluoroscopic visualizations to check system excitation light source, is used in the prior art with alleviating Inconvenient technical problem.
The embodiment of the invention provides a kind of fluoroscopic visualizations to check system excitation light source, including shell, light source bracket, laser Source, visible light source and observation channel;
The light source bracket, the laser source, the visible light source and the observation channel are arranged in the shell;
The light source bracket is set in the observation channel outer wall, and the laser source and the visible light source are arranged at institute It states on light source bracket;
Light collector is provided in the observation channel.
The first possible embodiment provided in an embodiment of the present invention, wherein the optical maser wavelength that above-mentioned laser source issues Between 781-789nm.
Second of possible embodiment provided in an embodiment of the present invention, wherein the optical maser wavelength that above-mentioned laser source issues For 785nm.
The third possible embodiment provided in an embodiment of the present invention, wherein be provided in above-mentioned observation channel multiple For detecting the detector of different wave length fluorescence.
4th kind of possible embodiment provided in an embodiment of the present invention, wherein above-mentioned detector includes for detecting wave Grow the first detector of 820-830nm, for Detection wavelength in the second detector of 830-840nm and for Detection wavelength In the third detector of 840-850nm.
5th kind of possible embodiment provided in an embodiment of the present invention, wherein be provided with and be used in above-mentioned observation channel Filter the optical filter of laser.
6th kind of possible embodiment provided in an embodiment of the present invention, wherein be provided with connection in above-mentioned observation channel Seat, the filter are detachably connected with the attachment base.
7th kind of possible embodiment provided in an embodiment of the present invention, wherein above-mentioned laser source and the visible light source It is fixedly connected with the light source bracket.
8th kind of possible embodiment provided in an embodiment of the present invention, wherein above-mentioned laser source and the visible light source It is disposed alternately on the light source bracket.
9th kind of possible embodiment provided in an embodiment of the present invention, wherein be provided on above-mentioned shell for controlling The switch of the laser source opening and closing.
The utility model has the advantages that
The embodiment of the invention provides a kind of fluoroscopic visualizations to check system excitation light source, including shell, light source bracket, laser Source, visible light source and observation channel;Light source bracket, laser source, visible light source and observation channel are arranged in shell;Light source branch Frame is set in observation channel outer wall, and laser source and visible light source are arranged on light source bracket;Light receipts are provided in observation channel Storage.When in use, shell is directly contacted with body tissue surface, and the exciting light of such body tissue surface reflection can be by device The exciting light for itself being blocked, and penetrating body tissue is irradiated to fluorescence caused by ICG, can but lead to from device center Road is penetrated, and is received by light collector, has been blocked skin or body tissue surface reflection to return the useless of fluorescence detection device and has been swashed It shines, avoids influence of a large amount of reflected excitation lights to picture, improve the signal-to-noise ratio of image, enhance image effect.Meanwhile Light collector can receive visible light source sending visible light, in post-processing, can by after fluorescence image processing with specific Color addition to the color image of visible light on, allow surgical staff to see the entirety of field of operation and therein simultaneously The case where lymph body, adapts to viewing and the thinking habit of surgical staff to the greatest extent, promotes procedure efficiency and correctness, convenient Surgical staff uses.
Other features and advantages of the present invention will illustrate in the following description, also, partly become from specification It obtains it is clear that understand through the implementation of the invention.The objectives and other advantages of the invention are in specification, claims And specifically noted structure is achieved and obtained in attached drawing.
To enable the above objects, features and advantages of the present invention to be clearer and more comprehensible, preferred embodiment is cited below particularly, and cooperate Appended attached drawing, is described in detail below.
Detailed description of the invention
It, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution in the prior art Embodiment or attached drawing needed to be used in the description of the prior art be briefly described, it should be apparent that, it is described below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is the structural schematic diagram that fluoroscopic visualization provided in an embodiment of the present invention checks system excitation light source;
Fig. 2 is the bottom view that fluoroscopic visualization provided in an embodiment of the present invention checks system excitation light source.
Icon: 100- shell;200- light source bracket;300- laser source;400- visible light source;500- observes channel; 510- detector;520- optical filter;530- attachment base;600- light collector;700- body tissue.
Specific embodiment
Technical solution of the present invention is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation Example is a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill Personnel's every other embodiment obtained without making creative work, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that, term " center ", " longitudinal direction ", " transverse direction ", " length ", " width ", " thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside", " up time The orientation or positional relationship of the instructions such as needle ", " counterclockwise ", " axial direction ", " radial direction ", " circumferential direction " be orientation based on the figure or Positional relationship is merely for convenience of description of the present invention and simplification of the description, rather than the device or element of indication or suggestion meaning must There must be specific orientation, be constructed and operated in a specific orientation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or Implicitly include one or more of the features.In the description of the present invention, the meaning of " plurality " is two or more, Unless otherwise specifically defined.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " fixation " etc. Term shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or integral;It can be mechanical connect It connects, is also possible to be electrically connected;It can be directly connected, can also can be in two elements indirectly connected through an intermediary The interaction relationship of the connection in portion or two elements.It for the ordinary skill in the art, can be according to specific feelings Condition understands the concrete meaning of above-mentioned term in the present invention.
The present invention is described in further detail below through specific implementation examples and in conjunction with the accompanying drawings.
With reference to shown in Fig. 1-Fig. 2:
The embodiment of the invention provides a kind of fluoroscopic visualizations to check system excitation light source, including shell 100, light source bracket 200, laser source 300, visible light source 400 and observation channel 500;Light source bracket 200, laser source 300, visible light source 400 and sight Channel 500 is examined to be arranged in shell 100;Light source bracket 200 is set in observation 500 outer wall of channel, laser source 300 and visible light Source 400 is arranged on light source bracket 200;Observation is provided with light collector 600 in channel 500.
The embodiment of the invention provides a kind of fluoroscopic visualizations to check system excitation light source, including shell 100, light source bracket 200, laser source 300, visible light source 400 and observation channel 500;Light source bracket 200, laser source 300, visible light source 400 and sight Channel 500 is examined to be arranged in shell 100;Light source bracket 200 is set in observation 500 outer wall of channel, laser source 300 and visible light Source 400 is arranged on light source bracket 200;Observation is provided with light collector 600 in channel 500.When in use, shell 100 with 700 surface of body tissue directly contacts, and the exciting light of such 700 surface reflection of body tissue can be blocked by device itself, and The exciting light for penetrating body tissue 700 is irradiated to fluorescence caused by ICG, but can the institute of channel 500 is thoroughly from device center It crosses, and is received by light collector 600, blocked skin or 700 surface reflection of body tissue to return the useless of fluorescence detection device and swashed It shines, avoids influence of a large amount of reflected excitation lights to picture, improve the signal-to-noise ratio of image, enhance image effect.Meanwhile Light collector 600 can receive the visible light of the sending of visible light source 400, can will be after fluorescence image processing in post-processing On the color image of specific color addition to visible light, allow surgical staff see simultaneously field of operation entirety and The case where lymph body therein, adapts to viewing and the thinking habit of surgical staff to the greatest extent, promotes procedure efficiency and correct Property, facilitate surgical staff to use.
By setting laser source 300 and visible light source 400, the laser that laser source 300 issues can excite on being irradiated to IGG Fluorescence, at this time fluorescence and visible light all can times light collector 600 collect, in subsequent imaging, medical worker can be from end The body tissue 700 containing fluorescent material and other body tissues without containing fluorescent material are clearly seen that in end display equipment 700, facilitate medical worker to operate and judge.
In the optinal plan of the present embodiment, the optical maser wavelength that laser source 300 issues is between 781-789nm.
In the optinal plan of the present embodiment, the optical maser wavelength that laser source 300 issues is 785nm.
Specifically, being irradiated by laser of the optical maser wavelength between 781-789nm to IGG, fluorescence can be improved Illumination effect further increases image effect.
Specifically, the optical maser wavelength that laser source 300 issues is 785nm.
In the optinal plan of the present embodiment, observes and be provided with multiple inspections for being used to detect different wave length fluorescence in channel 500 Survey device 510.
In the optinal plan of the present embodiment, detector 510 includes the first detection for Detection wavelength in 820-830nm Device 510, for Detection wavelength the second detector 510 of 830-840nm and for Detection wavelength 840-850nm third Detector 510.
Specifically, being provided with multiple detectors 510 in observation channel 500, multiple detectors 510 are different for receiving detection The fluorescence of wavelength, is then synthesized by processor, and the display effect of fluorescence imaging is improved.
In the optinal plan of the present embodiment, the optical filter 520 being provided in channel 500 for filtering laser is observed.
It is 781-789nm's to wavelength by optical filter 520 specifically, being provided with optical filter 520 in observation channel 500 Laser is filtered, and further increases fluorescence imaging effect.
In the optinal plan of the present embodiment, observes and be provided with attachment base 530 in channel 500, filter and attachment base 530 can Dismantling connection.
Specifically, being provided with attachment base 530 in observation channel 500, filter is removably arranged on attachment base 530, Filter can be replaced as needed.
In the optinal plan of the present embodiment, laser source 300 and visible light source 400 are fixedly connected with light source bracket 200.
In the optinal plan of the present embodiment, laser source 300 and visible light source 400 are disposed alternately on light source bracket 200.
Wherein, laser source 300 and visible light source 400 are fixed on light source bracket 200, and laser source 300 and can Light-exposed source 400 is arranged alternately.
In the optinal plan of the present embodiment, the switch for controlling the opening and closing of laser source 300 is provided on shell 100.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example Point is included at least one embodiment or example of the invention.In the present specification, schematic expression of the above terms are not It must be directed to identical embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be in office It can be combined in any suitable manner in one or more embodiment or examples.In addition, without conflicting with each other, the skill of this field Art personnel can tie the feature of different embodiments or examples described in this specification and different embodiments or examples It closes and combines.
Although the embodiments of the present invention has been shown and described above, it is to be understood that above-described embodiment is example Property, it is not considered as limiting the invention, those skilled in the art within the scope of the invention can be to above-mentioned Embodiment is changed, modifies, replacement and variant.

Claims (10)

1. a kind of fluoroscopic visualization checks system excitation light source characterized by comprising shell, light source bracket, laser source, visible Light source and observation channel;
The light source bracket, the laser source, the visible light source and the observation channel are arranged in the shell;
The light source bracket is set in the observation channel outer wall, and the laser source and the visible light source are arranged at the light On the bracket of source;
Light collector is provided in the observation channel.
2. fluoroscopic visualization according to claim 1 checks system excitation light source, which is characterized in that the laser source issued Optical maser wavelength is between 781-789nm.
3. fluoroscopic visualization according to claim 2 checks system excitation light source, which is characterized in that the laser source issued Optical maser wavelength is 785nm.
4. fluoroscopic visualization according to claim 1 checks system excitation light source, which is characterized in that set in the observation channel It is equipped with multiple for detecting the detector of different wave length fluorescence.
5. fluoroscopic visualization according to claim 4 checks system excitation light source, which is characterized in that the detector includes using It in the second detector of 830-840nm and is used in Detection wavelength in the first detector of 820-830nm, for Detection wavelength Third detector of the Detection wavelength in 840-850nm.
6. fluoroscopic visualization according to claim 1 checks system excitation light source, which is characterized in that set in the observation channel It is equipped with the optical filter for filtering laser.
7. fluoroscopic visualization according to claim 6 checks system excitation light source, which is characterized in that set in the observation channel It is equipped with attachment base, the filter is detachably connected with the attachment base.
8. fluoroscopic visualization according to claim 1 checks system excitation light source, which is characterized in that the laser source and described Visible light source is fixedly connected with the light source bracket.
9. fluoroscopic visualization according to claim 8 checks system excitation light source, which is characterized in that the laser source and described Visible light source is disposed alternately on the light source bracket.
10. -9 described in any item fluoroscopic visualizations check system excitation light source according to claim 1, which is characterized in that the shell The switch for controlling the laser source opening and closing is provided on body.
CN201811182748.2A 2018-10-10 2018-10-10 Fluoroscopic visualization checks system excitation light source Pending CN109171661A (en)

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Cited By (3)

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CN111458321A (en) * 2020-05-22 2020-07-28 南京诺源医疗器械有限公司 Diagnostic system based on lesion site fluorescence feedback
CN111493827A (en) * 2020-04-23 2020-08-07 南京诺源医疗器械有限公司 Fluorescence radiography inspection system based on 785nm wavelength light source
CN111803035A (en) * 2020-07-20 2020-10-23 重庆市中医院 Near-infrared lymph development detection system

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CN111803035A (en) * 2020-07-20 2020-10-23 重庆市中医院 Near-infrared lymph development detection system

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Application publication date: 20190111