CN109170900A - A kind of food compositions with liver-protecting and alcoholism-relieving health-care effect - Google Patents
A kind of food compositions with liver-protecting and alcoholism-relieving health-care effect Download PDFInfo
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- CN109170900A CN109170900A CN201811253293.9A CN201811253293A CN109170900A CN 109170900 A CN109170900 A CN 109170900A CN 201811253293 A CN201811253293 A CN 201811253293A CN 109170900 A CN109170900 A CN 109170900A
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/09—Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
- A23L21/20—Products from apiculture, e.g. royal jelly or pollen; Substitutes therefor
- A23L21/25—Honey; Honey substitutes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
- A23L25/30—Mashed or comminuted products, e.g. pulp, pastes, meal, powders; Products made therefrom, e.g. blocks, flakes, snacks; Liquid or semi-liquid products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention belongs to food or field of health care products more particularly to a kind of food compositions with liver-protecting and alcoholism-relieving health-care effect.Its constituent includes the substances such as silybum marianum seed, eucommia Bark male flower, dandelion, hoveniae semoveniae semen, roselle, swan-mussel polysaccharide.Paste is made after the extraction of effective component, mixing, drying, and it can be served, the advantage of each ingredient is utilized in food made of liver-protecting and alcoholism-relieving health-care food composition provided by the invention, on the one hand have the function of relieving the effect of alcohol after mutually acting synergistically, detoxify, protect liver, on the other hand it can enhance body immunity, and each component of the present invention is raw-food material, health has no toxic side effect, and is suitble to take for a long time.
Description
Technical field
The invention belongs to food or field of health care products more particularly to a kind of Combined foods with liver-protecting and alcoholism-relieving health-care effect
Object.
Background technique
Spirits culture is one of Chinese traditional culture treasure, of long standing and well established, about drink with caused by heavy drinking
Disease is just described in " The Yellow Emperor's Canon of Internal Medicine Ling Shu Miraculous Pivot or Divine Axis ": wine person, foodstuff essence enter in stomach, then gasteremphraxis, gas superinverse, Man Yu
In the heart, it is horizontal to float gallbladder for liver.It can be seen that heavy drinking has serious harm to internal organs such as human stomach, liver and gallbladder.Modern medicine shows heavy drinking
There is different degrees of harm to the digestive system of human body, nervous system, skeletal system, hemopoietic system.
With the continuous improvement of China's national life level, China liquor consumption person crowd and liquor consumption amount are all very
Surprising therefore anti-intoxication, gentle solution of quickly the relieving the effect of alcohol target for becoming everybody and pursuing jointly uncomfortable after drinking.Alcohol after drinking
Respectively can be in alimentary canal, duodenum, ileum, big intestinal absorption, duodenal absorption is most fast most, finally carries out generation in liver
It thanks, there are three types of approach in liver metabolism for alcohol: the two kinds of enzymes (alcohol dehydrogenase, acetaldehyde dehydrogenase) generated by liver are come generation
It thanks, alcohol first passes through alcohol dehydrogenase and generates acetic acid, and the acetaldehyde of generation is again by generating harmless acid with acetaldehyde-dehydrogenase enzyme reaction
Class, while acetaldehyde can also stimulate adrenaline secretion to cause the diseases such as flushing body heat in the metabolic process.Ethyl alcohol into cross cytochromes
It is metabolized into acetic acid, then is metabolized by acetic acid dehydrogenase.Urethra, skin can be passed through in the ethyl alcohol that above two method has not been metabolized also
It is metabolized out external.Drunk drunk mechanism is exactly largely to drink, and the speed of internal alcohol metabolism is slower than the suction of ethyl alcohol in vivo
Speed is received, a large amount of alcohol passes through blood circulation in vivo and enters brain, acts on brain stem reticular formation first, cause brain emerging
Put forth energy, after reaching a certain concentration, cerebral cortex start generate sleep consciousness, finally generate anesthetic stupor, caused by acute wine
The phenomenon that essence poisoning.When ethanol in blood concentration when, people starts to generate dim sense, reaches in concentration, and people paces are unstable, language without
Coherence, if haemoconcentration is more than, people will be in peril of one's life.The oxidative metabolism for accelerating ethyl alcohol in vivo is drunk into intracorporal alcohol
It is to be decomposed by liver metabolism above, it is possible to which exploitation improves relieving the effect of alcohol for ethyl alcohol deoxygenase and aldehyde dehydrogenase activity in liver
Functional product is improved by the activity of the above two key enzyme that relieves the effect of alcohol, achievees the effect that alcohol in rapid decomposer.Alcohol is in people
In body metabolic process, a large amount of various free radicals can be generated, there are also intermediate products etc., they can be to internal superoxide dismutase
Activated centre metal ligand field and cell differentiation play destruction, and superoxide dismutase is human body alcohol metabolism key enzyme,
Therefore it can mitigate superoxide dismutase burden by Scavenging ability in intensive aspect, while protection can be played to it and made
With.
Domestic alcohol user's radix is huge, and alcoholism is customary, and does not see a doctor mostly.Cirrhosis is generated due to caused by alcohol
Person accounts for 5% or so.Driver, which drivings a car under the influence of alcohol, to have a car accident, and causes heavy losses and pain to society and family.
Therefore the medicament and health food inquired into and sobered up, relieve the effect of alcohol are the big projects paid close attention to jointly both at home and abroad.With each national literature
Person recognizes the further research of acute alcoholic mechanism of poisoning, and more and more relieving alcoholism and preventing drunkenness drugs, health care product come out, but solve
Yeast for brewing rice wine effect is quick not as good as Western medicine, and because Western medicine has therefore how toxic side effect measures the drug effect of relieving the effect of alcohol of product, increasingly
By public concern, research has no toxic side effect, and quick, effective antialcoholic drug becomes trend.
Summary of the invention
It is a kind of with liver-protecting and alcoholism-relieving health-care effect present invention aims to provide for the presence for solving the problems, such as the prior art
Food compositions, dispelling effects of alcohol is significant, quick and have no toxic side effect.
To achieve the above object, the present invention the following technical schemes are provided:
A kind of food compositions with liver-protecting and alcoholism-relieving health-care effect, in parts by weight, including following components: powder-refining with water
1-5 parts of Ji seed, 0.1-1 parts of eucommia Bark male flower, 1-5 parts of dandelion, 1-5 parts of hoveniae semoveniae semen, 0.1-1 parts of roselle, swan-mussel polysaccharide 1-5
Part.
Further, the food compositions with liver-protecting and alcoholism-relieving health-care effect, in parts by weight, also comprising with
Lower component: 0.5-2 parts of Poria cocos, 0.1-0.5 parts of leucine, 0.1-1.5 parts of maize oligopeptide, 1-5 parts of pueraria lobata, turmeric 0.01-0.1
Part.
Further, the food compositions with liver-protecting and alcoholism-relieving health-care effect, in parts by weight, also comprising with
Lower component: 1-3 parts of Radix Glycyrrhizae, 1-2 parts of lily, 0.1-2 parts of hydrolyzing lactoalbumin powder, 0.1-2 parts of powdered soybean phospholipid.
Further, the food compositions with liver-protecting and alcoholism-relieving health-care effect, in parts by weight, also comprising with
Lower component: 0.1-3 parts of banana, 0.1-1 parts of dried orange peel, 1-3 parts of sesame, 0.5-3 parts of fructus lycii.
Further, the food compositions with liver-protecting and alcoholism-relieving health-care effect, in parts by weight, also comprising with
Lower component: 0.1-1 parts of jujube, 0.1-1 parts of brown sugar, 1-4 parts of lotus root starch, 0.1-5 parts of honey.
Another object of the present invention, which also resides in, provides a kind of system of food compositions with liver-protecting and alcoholism-relieving health-care effect
Preparation Method, comprising the following steps:
(1) silybum marianum seed, dandelion, hoveniae semoveniae semen are weighed and is ground into particle, degreasing, product is stand-by;
(2) component roselle, eucommia Bark male flower are weighed, places in ethyl alcohol and extracts together with product in (1), obtain leaching liquor;
(3) it is evaporated under reduced pressure after leaching liquor in (2) being carried out ultrasound, recycles the dehydrated alcohol in leaching liquor, concentration must be concentrated
Liquid;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide, obtain extracting solution, adjusts pH, heated at constant temperature, deproteinized,
Centrifugation, takes supernatant, is concentrated under reduced pressure, and product adds ethanol precipitation after concentration, stands, and centrifuging and taking precipitating weighs swan-mussel polysaccharide product
It is spare;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtain dispersion liquid, it is dry
To paste;
Further, component also includes Poria cocos, pueraria lobata, turmeric, the pulverized particles of Radix Glycyrrhizae and lily, dried orange peel in step (2);
Preferably, above-mentioned Poria cocos, Radix Glycyrrhizae, pueraria lobata, turmeric pulverized particles cross the sieve of 10-40 mesh;
It further, further include that leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin is added in dispersion liquid in step (5)
Powder, powdered soybean phospholipid;
Further, further include in dispersion liquid in step (5) be added banana, sesame, fructus lycii and jujube, brown sugar, lotus root starch,
Honey.
Preferably, particle described in (1) crosses the sieve of 10-40 mesh;
Preferably, the concentration of ethyl alcohol is 85-95% in (2), and weight is 3-6 times of component weight, extraction time 20-
60h;
It is highly preferred that condition ultrasonic in (3) is 200-250W, 60-100kHz, the ultrasonic time is 1-2h;
It is highly preferred that condition ultrasonic in (4) is 200-250W, 60-100kHz;PH value is 6-8;The temperature of heating is
70-90 DEG C, the time of heating is 20-60min;The revolving speed of centrifugation is 1500-3000r/min, and the time of centrifugation is 7-15min;
Concentration of alcohol is 70-95%, and dosage is 2-3 times of products weight after concentration;
It is highly preferred that temperature dry in (5) is 20-40 DEG C, the dry time is 6-8h.
Another object of the present invention, which also resides in provide, has the food compositions of liver-protecting and alcoholism-relieving health-care effect in relieving alcoholism and protecting liver
Application in health care product.
The present invention compared with the prior art, it has the advantage that:
(1) it can cooperate with and play a role between liver-protecting and alcoholism-relieving health-care food composition each component provided by the invention, with water
Fly based on the food with antialcoholism function such as Ji seed, eucommia Bark male flower, hoveniae semoveniae semen, roselle, addition dandelion, swan-mussel polysaccharide etc. are more
The ingredient of kind liver protection effect, auxiliary pueraria lobata, Poria cocos, sesame etc. have effects that the ingredient of beneficial stomach invigorating the spleen.In addition, banana, Radix Glycyrrhizae, old
The components such as skin peomote silybum marianum seed and eucommia Bark male flower plays one's part to the full;Maize oligopeptide, the hydrolyzed whey egg of addition
White powder, powdered soybean phospholipid etc. facilitate strengthen immunity, enhance liver detoxification function, body can be promoted effective to each component
The problem of absorption of ingredient, enhances human immunity comprehensively, further improves the drunk impariment of the liver.
(2) present invention is to further increase the effect of composition, by roselle, lily, eucommia Bark male flower, silybum marianum seed,
Dandelion, hoveniae semoveniae semen, freshwater mussel meat, turmeric, pueraria lobata, Poria cocos, Radix Glycyrrhizae, dried orange peel are extracted, and effective component is extracted and is enriched with, is mentioned
Each effective component interaction, can more play drug effect during taking, and be conducive to achieve the purpose that relieve the effect of alcohol, protect liver.
(3) present invention gradually mixes the effective component after extraction, makes each component mixing completely, uniformly, can better phase
Interaction, and there is good pharmacodynamic stability, be conducive to the performance to act synergistically between component;And add during mixing
Add honey, brown sugar etc., promotes to generate stronger cooperative effect.
(4) on the one hand liver-protecting and alcoholism-relieving health-care food composition provided by the invention has the function of relieving the effect of alcohol, detoxify, protect liver,
On the other hand it can enhance body immunity, and each component of the present invention is raw-food material, health has no toxic side effect, and is suitble to long-term
It takes.
Specific embodiment
Embodiment 1
Composite formula: 1 part of silybum marianum seed, 1 part of eucommia Bark male flower, 5 parts of dandelion, 1 part of hoveniae semoveniae semen, 0.1 part of roselle, freshwater mussel
5 parts of meat polysaccharide.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen are weighed and is ground into particle, the sieve of 10 mesh, degreasing, product excessively is stand-by;
(2) component roselle, eucommia Bark male flower are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtained
Leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtains dispersion liquid, 40 DEG C
The dry 6h of vacuum oven to paste.
Embodiment 2
Composite formula: 5 parts of silybum marianum seed, 0.1 part of eucommia Bark male flower, 1 part of dandelion, 5 parts of hoveniae semoveniae semen, 1 part of roselle, freshwater mussel
1 part of meat polysaccharide.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen are weighed and is ground into particle, the sieve of 10 mesh, degreasing, product excessively is stand-by;
(2) component roselle, eucommia Bark male flower are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtained
Leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtains dispersion liquid, 40 DEG C
The dry 6h of vacuum oven to paste.
Embodiment 3
Composite formula: 1 part of silybum marianum seed, 1 part of eucommia Bark male flower, 5 parts of dandelion, 1 part of hoveniae semoveniae semen, 0.1 part of roselle, freshwater mussel
5 parts of meat polysaccharide, 0.5 part of Poria cocos, 0.5 part of leucine, 0.1 part of maize oligopeptide, 5 parts of pueraria lobata, 0.01 part of turmeric.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric are weighed and is ground into particle, crosses 10 purposes
Sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtained
Leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by product, the leucine, Semen Maydis oligosaccharide in concentrate in above-mentioned (3), (4), it is added to the water together, stirs
It mixes, obtains dispersion liquid, the dry 6h of 40 DEG C of vacuum oven to paste.
Embodiment 4
Composite formula: 5 parts of silybum marianum seed, 0.1 part of eucommia Bark male flower, 1 part of dandelion, 5 parts of hoveniae semoveniae semen, 1 part of roselle, freshwater mussel
1 part of meat polysaccharide, 2 parts of Poria cocos, 0.1 part of leucine, 1.5 parts of maize oligopeptide, 1 part of pueraria lobata, 0.1 part of turmeric.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric are weighed and is ground into particle, crosses 10 purposes
Sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtained
Leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by product, the leucine, Semen Maydis oligosaccharide in concentrate in above-mentioned (3), (4), it is added to the water together, stirs
It mixes, obtains dispersion liquid, the dry 6h of 40 DEG C of vacuum oven to paste.
Embodiment 5
Composite formula: 1 part of silybum marianum seed, 1 part of eucommia Bark male flower, 5 parts of dandelion, 1 part of hoveniae semoveniae semen, 0.1 part of roselle, freshwater mussel
5 parts of meat polysaccharide, 0.5 part of Poria cocos, 0.5 part of leucine, 0.1 part of maize oligopeptide, 5 parts of pueraria lobata, 0.01 part of turmeric, 3 parts of Radix Glycyrrhizae, hundred
Close 1 part, 2 parts of hydrolyzing lactoalbumin powder, 0.1 part of powdered soybean phospholipid.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric, Radix Glycyrrhizae are weighed and is ground into particle, crosses 10
Purpose sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower, lily are weighed, places with product in (1) and is extracted in 85% ethyl alcohol together
60h obtains leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product, leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, big in concentrate in above-mentioned (3), (4)
Beans powder phospholipid, is added to the water together, stirs and evenly mixs, and obtains dispersion liquid, the dry 6h of 40 DEG C of vacuum oven to paste.
Embodiment 6
Composite formula: 5 parts of silybum marianum seed, 0.1 part of eucommia Bark male flower, 1 part of dandelion, 5 parts of hoveniae semoveniae semen, 1 part of roselle, freshwater mussel
1 part of meat polysaccharide, 2 parts of Poria cocos, 0.1 part of leucine, 1.5 parts of maize oligopeptide, 1 part of pueraria lobata, 0.1 part of turmeric, 1 part of Radix Glycyrrhizae, lily 2
Part, 0.1 part of hydrolyzing lactoalbumin powder, 2 parts of powdered soybean phospholipid.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric, Radix Glycyrrhizae are weighed and is ground into particle, crosses 10
Purpose sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower, lily are weighed, places with product in (1) and is extracted in 85% ethyl alcohol together
60h obtains leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product, leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, big in concentrate in above-mentioned (3), (4)
Beans powder phospholipid, is added to the water together, stirs and evenly mixs, and obtains dispersion liquid, the dry 6h of 40 DEG C of vacuum oven to paste.
Embodiment 7
Composite formula: 1 part of silybum marianum seed, 1 part of eucommia Bark male flower, 5 parts of dandelion, 1 part of hoveniae semoveniae semen, 0.1 part of roselle, freshwater mussel
5 parts of meat polysaccharide, 0.5 part of Poria cocos, 0.5 part of leucine, 0.1 part of maize oligopeptide, 5 parts of pueraria lobata, 0.01 part of turmeric, 3 parts of Radix Glycyrrhizae, hundred
Close 1 part, 2 parts of hydrolyzing lactoalbumin powder, 0.1 part of powdered soybean phospholipid, 0.1 part of banana, 1 part of dried orange peel, 1 part of sesame, fructus lycii 0.5
Part.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric, Radix Glycyrrhizae are weighed and is ground into particle, crosses 10
Purpose sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower, lily, dried orange peel are weighed, is placed together with product in (1) in 85% ethyl alcohol
60h is extracted, leaching liquor is obtained;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product, leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, big in concentrate in above-mentioned (3), (4)
Beans powder phospholipid, banana, sesame, fructus lycii, are added to the water together, stir and evenly mix, and obtain dispersion liquid, and 40 DEG C of vacuum oven is dry
6h is to paste.
Embodiment 8
Composite formula: 5 parts of silybum marianum seed, 0.1 part of eucommia Bark male flower, 1 part of dandelion, 5 parts of hoveniae semoveniae semen, 1 part of roselle, freshwater mussel
1 part of meat polysaccharide, 2 parts of Poria cocos, 0.1 part of leucine, 1.5 parts of maize oligopeptide, 1 part of pueraria lobata, 0.1 part of turmeric, 1 part of Radix Glycyrrhizae, lily 2
Part, 0.1 part of hydrolyzing lactoalbumin powder, 2 parts of powdered soybean phospholipid, 3 parts of banana, 0.1 part of dried orange peel, 3 parts of sesame, 3 parts of fructus lycii.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric, Radix Glycyrrhizae are weighed and is ground into particle, crosses 10
Purpose sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower, lily, dried orange peel are weighed, is placed together with product in (1) in 85% ethyl alcohol
60h is extracted, leaching liquor is obtained;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product, leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, big in concentrate in above-mentioned (3), (4)
Beans powder phospholipid, banana, sesame, fructus lycii, are added to the water together, stir and evenly mix, and obtain dispersion liquid, and 40 DEG C of vacuum oven is dry
6h is to paste.
Embodiment 9
Composite formula: 1 part of silybum marianum seed, 1 part of eucommia Bark male flower, 5 parts of dandelion, 1 part of hoveniae semoveniae semen, 0.1 part of roselle, freshwater mussel
5 parts of meat polysaccharide, 0.5 part of Poria cocos, 0.5 part of leucine, 0.1 part of maize oligopeptide, 5 parts of pueraria lobata, 0.01 part of turmeric, 3 parts of Radix Glycyrrhizae, hundred
Close 1 part, 2 parts of hydrolyzing lactoalbumin powder, 0.1 part of powdered soybean phospholipid, 0.1 part of banana, 1 part of dried orange peel, 1 part of sesame, fructus lycii 0.5
Part, 0.1 part of jujube, 1 part of brown sugar, 4 parts of lotus root starch, 5 parts of honey.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric, Radix Glycyrrhizae are weighed and is ground into particle, crosses 10
Purpose sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower, lily, dried orange peel are weighed, is placed together with product in (1) in 85% ethyl alcohol
60h is extracted, leaching liquor is obtained;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product, leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, big in concentrate in above-mentioned (3), (4)
Beans powder phospholipid, banana, sesame, fructus lycii, jujube, brown sugar, lotus root starch, honey, are added to the water together, stir and evenly mix, and obtain dispersion liquid,
40 DEG C of vacuum oven dries 6h to paste.
Embodiment 10
Composite formula: 5 parts of silybum marianum seed, 0.1 part of eucommia Bark male flower, 1 part of dandelion, 5 parts of hoveniae semoveniae semen, 1 part of roselle, freshwater mussel
1 part of meat polysaccharide, 2 parts of Poria cocos, 0.1 part of leucine, 1.5 parts of maize oligopeptide, 1 part of pueraria lobata, 0.1 part of turmeric, 1 part of Radix Glycyrrhizae, lily 2
Part, 0.1 part of hydrolyzing lactoalbumin powder, 2 parts of powdered soybean phospholipid, 3 parts of banana, 0.1 part of dried orange peel, 3 parts of sesame, 3 parts of fructus lycii, jujube
1 part, 0.1 part of brown sugar, 1 part of lotus root starch, 0.1 part of honey.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric, Radix Glycyrrhizae are weighed and is ground into particle, crosses 10
Purpose sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower, lily, dried orange peel are weighed, is placed together with product in (1) in 85% ethyl alcohol
60h is extracted, leaching liquor is obtained;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 6,90 DEG C, heated at constant temperature 60min, deproteinized, to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant, subtracts revolving speed
Pressure concentration, product adds 3 times 70% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product, leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, big in concentrate in above-mentioned (3), (4)
Beans powder phospholipid, banana, sesame, fructus lycii, jujube, brown sugar, lotus root starch, honey, are added to the water together, stir and evenly mix, and obtain dispersion liquid,
40 DEG C of vacuum oven dries 6h to paste.
Embodiment 11
Composite formula: 5 parts of silybum marianum seed, 0.1 part of eucommia Bark male flower, 1 part of dandelion, 5 parts of hoveniae semoveniae semen, 1 part of roselle, freshwater mussel
1 part of meat polysaccharide, 2 parts of Poria cocos, 0.1 part of leucine, 1.5 parts of maize oligopeptide, 1 part of pueraria lobata, 0.1 part of turmeric, 1 part of Radix Glycyrrhizae, lily 2
Part, 0.1 part of hydrolyzing lactoalbumin powder, 2 parts of powdered soybean phospholipid, 3 parts of banana, 0.1 part of dried orange peel, 3 parts of sesame, 3 parts of fructus lycii, jujube
1 part, 0.1 part of brown sugar, 1 part of lotus root starch, 0.1 part of honey.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric, Radix Glycyrrhizae are weighed and is ground into particle, crosses 40
Purpose sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower, lily, dried orange peel are weighed, is placed together with product in (1) in 95% ethyl alcohol
20h is extracted, leaching liquor is obtained;Wherein, ethyl alcohol weight is (1), 6 times of each component total weight in (2);
(3) by leaching liquor 200W in (2), ultrasound 1h being carried out under the conditions of 100kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, is added water ultrasonic extraction swan-mussel polysaccharide under the conditions of 200W, 100kHz, obtain extracting solution, is adjusted
PH to 8, at 70 DEG C, heated at constant temperature 20min, deproteinized, revolving speed is centrifuged 7min under the conditions of being 3000r/min, is centrifuged, takes supernatant,
It is concentrated under reduced pressure, product adds 2 times 95% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
By product, the leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, soybean in concentrate in above-mentioned (3), (4)
Powder phospholipid, banana, sesame, fructus lycii, jujube, brown sugar, lotus root starch, honey, are added to the water together, stir and evenly mix,
Obtain dispersion liquid, the dry 8h of 20 DEG C of vacuum oven to paste.
Comparative example 1 is free of the liver-protecting and alcoholism-relieving health-care food composition of silybum marianum seed
Composite formula: in addition to without silybum marianum seed, remaining is the same as embodiment 1.
Preparation method:
(1) weigh component dandelion, hoveniae semoveniae semen is ground into particle, cross the sieve of 10 mesh, degreasing, product is stand-by;
(2) component roselle, eucommia Bark male flower are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtained
Leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) with embodiment 1;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtains dispersion liquid, 40 DEG C
The dry 6h of vacuum oven to paste.
Comparative example 2 is free of the liver-protecting and alcoholism-relieving health-care food composition of dandelion
Composite formula: in addition to without dandelion, remaining is the same as embodiment 1.
Preparation method:
(1) weigh component silybum marianum seed, hoveniae semoveniae semen is ground into particle, cross the sieve of 10 mesh, degreasing, product is stand-by;
(2) component roselle, eucommia Bark male flower are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtained
Leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) with embodiment 1;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtains dispersion liquid, 40 DEG C
The dry 6h of vacuum oven to paste.
Comparative example 3 is free of the liver-protecting and alcoholism-relieving health-care food composition of hoveniae semoveniae semen
Composite formula: in addition to without hoveniae semoveniae semen, remaining is the same as embodiment 1.
Preparation method:
(1) weigh component silybum marianum seed, dandelion is ground into particle, cross the sieve of 10 mesh, degreasing, product is stand-by;
(2) component roselle, eucommia Bark male flower are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtained
Leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) with embodiment 1;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtains dispersion liquid, 40 DEG C
The dry 6h of vacuum oven to paste.
Comparative example 4 is free of the liver-protecting and alcoholism-relieving health-care food composition of roselle
Composite formula: in addition to without roselle, remaining is the same as embodiment 1.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen are weighed and is ground into particle, the sieve of 10 mesh, degreasing, product excessively is stand-by;
(2) component eucommia Bark male flower is weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtain leaching liquor;
Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) with embodiment 1;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtains dispersion liquid, 40 DEG C
The dry 6h of vacuum oven to paste.
Comparative example 5 is free of the liver-protecting and alcoholism-relieving health-care food composition of eucommia Bark male flower
Composite formula: in addition to without eucommia Bark male flower, remaining is the same as embodiment 1.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen are weighed and is ground into particle, the sieve of 10 mesh, degreasing, product excessively is stand-by;
(2) component roselle is weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtain leaching liquor;Its
In, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) with embodiment 1;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtains dispersion liquid, 40 DEG C
The dry 6h of vacuum oven to paste.
Comparative example 6 is free of the liver-protecting and alcoholism-relieving health-care food composition of swan-mussel polysaccharide
Composite formula: in addition to without swan-mussel polysaccharide, remaining is the same as embodiment 1.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen are weighed and is ground into particle, the sieve of 10 mesh, degreasing, product excessively is stand-by;
(2) component roselle, eucommia Bark male flower are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h, obtained
Leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) by concentrate in above-mentioned (3), the dry 6h of 40 DEG C of vacuum oven to paste.
The liver-protecting and alcoholism-relieving health-care food composition of 7 distinct methods of comparative example preparation
Composite formula: with embodiment 9.
Preparation method:
(1) component silybum marianum seed, dandelion, hoveniae semoveniae semen, Poria cocos, pueraria lobata, turmeric, Radix Glycyrrhizae are weighed and is ground into particle, crosses 50
Purpose sieve, degreasing, product are stand-by;
(2) component roselle, eucommia Bark male flower, lily, dried orange peel are weighed, is placed together with product in (1) in 60% ethyl alcohol
60h is extracted, leaching liquor is obtained;Wherein, ethyl alcohol weight is (1), 7 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide under the conditions of 250W, 60kHz, obtains extracting solution, adjusts pH
To at 9,60 DEG C, heated at constant temperature 100min, deproteinized, for revolving speed to be centrifuged 15min under the conditions of 1500r/min, centrifugation takes supernatant,
It is concentrated under reduced pressure, product adds 3 times 60% of ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product, leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, big in concentrate in above-mentioned (3), (4)
Beans powder phospholipid, banana, sesame, fructus lycii, jujube, brown sugar, lotus root starch, honey, are added to the water together, stir and evenly mix, and obtain dispersion liquid,
50 DEG C of vacuum oven dries 5h to paste.
The liver-protecting and alcoholism-relieving health-care food composition of 8 distinct methods of comparative example preparation
Composite formula: with embodiment 9.
Preparation method: in addition to swan-mussel polysaccharide preparation method is different, remaining is the same as embodiment 9.
(1)-(3) are the same as embodiment 9
(4) freshwater mussel meat is weighed, is homogenized, adds water tune pH to 6, at 90 DEG C, heated at constant temperature 4h extraction, 1500r/min centrifugation point
From, filter, to be concentrated to give swan-mussel polysaccharide product spare;
(5) with embodiment 9.
The liver-protecting and alcoholism-relieving health-care food composition of 9 distinct methods of comparative example preparation
Composite formula: with embodiment 9.
Preparation method: in addition to roselle preparation method is different, remaining is the same as embodiment 9.
(1) with embodiment 9.
(2) component eucommia Bark male flower, lily, dried orange peel are weighed, is placed together with product in (1) in 85% ethyl alcohol and extracts 60h,
Obtain leaching liquor;Wherein, ethyl alcohol weight is (1), 3 times of each component total weight in (2);
(3) by leaching liquor 250W in (2), ultrasound 2h being carried out under the conditions of 60kHz, is evaporated under reduced pressure later, recycling extracts
Dehydrated alcohol in liquid, concentration, obtains concentrate;
(4) with embodiment 9;
(5) roselle is weighed, 3 times of water is added, decocting 4h, after concentration, product is spare;
(6) by product, the leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin in concentrate in above-mentioned (3), (4), (5)
Powder, powdered soybean phospholipid, banana, sesame, fructus lycii, jujube, brown sugar, lotus root starch, honey, are added to the water together, stir and evenly mix, score
Dispersion liquid, the dry 6h of 40 DEG C of vacuum oven to paste.
Effect example
Group technology: KM mouse 180, half male and half female, weight 20g or so is randomly divided into:
Blank control group, positive drug group, 1 high and low dose group of the embodiment of the present invention, 3,5,7,9,11 low dosage of embodiment
Group, comparative example 1-9 low dose group, every group 10.
Low dose group: 4.0g/kg;
High dose group: 8.0g/kg;.
Positive drug selects sea Wang Jin cup: 4.0g/kg;
Blank group: feeding physiological saline 4.0g/kg;
First " medicine " the anti-intoxication pharmacodynamic test of " wine " mouse afterwards of experimental method
After mouse is set according to above-mentioned group technology, before testing after fasting 12h, the amount set according to every group is given
Drug, after stomach-filling, every group fills 56 ° of strong, colourless liquor distilled from sorghum after 30min with 30ml/kg dosage, gets started timing, records each group
Drunk (righting reflex loss) and sober up (righting reflex recovery) time, while calculating the sleep latency of mouse and small
The sleeping time of mouse.Experimental result is the following table 1.
1 pharmacodynamic test effect table of table
A is indicated and blank group ratio P < 0.05, b are indicated and positive controls ratio P < 0.05.
By upper table experimental data it is found that the formula such as the low, high dose being formulated according to embodiment 1 and embodiment 3,5,7,9,11
After mouse medicine feed, sleep latency is elongated relative to blank group, and the time of sobering up shortens, and the death rate reduces, this illustrates this
The composite formula of application has preferable liver-protecting and alcoholism-relieving effect;In addition, the formula such as embodiment 1,3,5,7 of low dosage and the positive
Control group is compared, and mice sleep latent time is roughly the same, meanwhile, the reality of the formulas and high dose such as embodiment 9,11 of low dosage
It applies 1 group of sleep latency of example and is longer than positive controls, this illustrates the more conventional antialcoholic drug of the formula of the application on an equal basis or more
Good dispelling effects of alcohol.
First " wine " " medicine " mouse is sobered up pharmacodynamic test afterwards
Mouse is set according to above-mentioned group technology, before testing after fasting, every group with the filling of dosage 30ml/kg dosage
56 ° of strong, colourless liquor distilled from sorghum after 30min, according to the group technology grouping set and feeding relative medicine, after stomach-filling, are got started
Timing, record are sobered up (righting reflex recovery) time, the results are shown in Table 2.
2 pharmacodynamic test effect table of table
A is indicated and blank group ratio P < 0.05, b are indicated and positive controls ratio P < 0.05.
By upper table experimental data it is found that compared to blank group and positive controls, according to low, the high agent of the formula of embodiment 1
After the formula such as amount and embodiment 3,5,7,9,11 is to mouse medicine feed, the time of sobering up of mouse shortens, drunk number, sleep number and death
Rate reduces, this illustrates that the composite formula of the application has the effect of preferable relieving alcoholism and protecting liver.
Above-mentioned detailed description is illustrating for one of them possible embodiments of the present invention, the embodiment not to
The scope of the patents of the invention is limited, all equivalence enforcements or change without departing from carried out by the present invention are intended to be limited solely by the technology of the present invention
In the range of scheme.
Claims (10)
1. a kind of food compositions with liver-protecting and alcoholism-relieving health-care effect, which is characterized in that in parts by weight, including it is following
Component: 1-5 parts of silybum marianum seed, 0.1-1 parts of eucommia Bark male flower, 1-5 parts of dandelion, 1-5 parts of hoveniae semoveniae semen, 0.1-1 parts of roselle, freshwater mussel meat
1-5 parts of polysaccharide.
2. as described in claim 1 with the food compositions of liver-protecting and alcoholism-relieving health-care effect, which is characterized in that according to parts by weight
Number meter also includes following components: 0.5-2 parts of Poria cocos, 0.1-0.5 parts of leucine, 0.1-1.5 parts of maize oligopeptide, pueraria lobata 1-5
Part, 0.01-0.1 parts of turmeric.
3. as claimed in claim 2 with the food compositions of liver-protecting and alcoholism-relieving health-care effect, which is characterized in that according to parts by weight
Number meter also includes following components: 1-3 parts of Radix Glycyrrhizae, 1-2 parts of lily, 0.1-2 parts of hydrolyzing lactoalbumin powder, powdered soybean phospholipid
0.1-2 parts.
4. as claimed in claim 3 with the food compositions of liver-protecting and alcoholism-relieving health-care effect, which is characterized in that according to parts by weight
Number meter also includes following components: 0.1-3 parts of banana, 0.1-1 parts of dried orange peel, 1-3 parts of sesame, 0.5-3 parts of fructus lycii.
5. as claimed in claim 4 with the food compositions of liver-protecting and alcoholism-relieving health-care effect, which is characterized in that according to parts by weight
Number meter also includes following components: 0.1-1 parts of jujube, 0.1-1 parts of brown sugar, 1-4 parts of lotus root starch, 0.1-5 parts of honey.
6. a kind of preparation method of the food compositions with liver-protecting and alcoholism-relieving health-care effect as described in claim 1, including with
Lower step:
(1) silybum marianum seed, dandelion, hoveniae semoveniae semen are weighed and is ground into particle, degreasing, product is stand-by;
(2) component roselle, eucommia Bark male flower are weighed, places in ethyl alcohol and extracts together with product in (1), obtain leaching liquor;
(3) it is evaporated under reduced pressure after leaching liquor in (2) being carried out ultrasound, recycles the dehydrated alcohol in leaching liquor, concentration obtains concentrate;
(4) freshwater mussel meat is weighed, is homogenized, adds water ultrasonic extraction swan-mussel polysaccharide, obtains extracting solution, adjusts pH, heated at constant temperature, deproteinized is centrifuged,
Supernatant is taken, is concentrated under reduced pressure, product adds ethanol precipitation after concentration, stands, and it is spare to weigh swan-mussel polysaccharide product for centrifuging and taking precipitating;
(5) by the product in concentrate in above-mentioned (3), (4), it is added to the water together, stirs and evenly mixs, obtains dispersion liquid, it is dry to cream
Shape.
7. the preparation method of the food compositions with liver-protecting and alcoholism-relieving health-care effect as claimed in claim 6, which is characterized in that
Component also includes Poria cocos, pueraria lobata, turmeric, the pulverized particles of Radix Glycyrrhizae and lily, dried orange peel in step (2).
8. the preparation method of the food compositions with liver-protecting and alcoholism-relieving health-care effect as claimed in claim 7, which is characterized in that
It further include that leucine, Semen Maydis oligosaccharide, hydrolyzing lactoalbumin powder, powdered soybean phospholipid is added in dispersion liquid in step (5).
9. the preparation method of the food compositions with liver-protecting and alcoholism-relieving health-care effect as claimed in claim 8, which is characterized in that
It further include that banana, sesame, fructus lycii and jujube, brown sugar, lotus root starch, honey is added in dispersion liquid in step (5).
10. the food compositions as described in claim 1-9 is any with liver-protecting and alcoholism-relieving health-care effect are in relieving alcoholism and protecting liver health care product
In application.
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CN110663960A (en) * | 2019-08-23 | 2020-01-10 | 北京康爱营养医学研究院 | Nutritional composition and preparation method and application thereof |
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