CN109153675B - 细胞周期蛋白依赖性激酶9通过cdk9抑制剂与e3连接酶配体的缀合的降解及使用方法 - Google Patents

细胞周期蛋白依赖性激酶9通过cdk9抑制剂与e3连接酶配体的缀合的降解及使用方法 Download PDF

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CN109153675B
CN109153675B CN201780024826.3A CN201780024826A CN109153675B CN 109153675 B CN109153675 B CN 109153675B CN 201780024826 A CN201780024826 A CN 201780024826A CN 109153675 B CN109153675 B CN 109153675B
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cancer
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disease
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cdk9
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CN109153675A (zh
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N.格雷
T.张
C.M.奥尔森
Y.梁
N.奎亚特科夫斯基
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Dana Farber Cancer Institute Inc
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CN201780024826.3A 2016-04-22 2017-04-21 细胞周期蛋白依赖性激酶9通过cdk9抑制剂与e3连接酶配体的缀合的降解及使用方法 Active CN109153675B (zh)

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PCT/US2017/028924 WO2017185023A1 (en) 2016-04-22 2017-04-21 Degradation of cyclin-dependent kinase 9 (cdk9) by conjugation of cdk9 inhibitors with e3 ligase ligand and methods of use

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