CN109152773A - 用于治疗无烟烟草成瘾的含有大麻二酚和尼古丁的药物制剂 - Google Patents

用于治疗无烟烟草成瘾的含有大麻二酚和尼古丁的药物制剂 Download PDF

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Publication number
CN109152773A
CN109152773A CN201780028842.XA CN201780028842A CN109152773A CN 109152773 A CN109152773 A CN 109152773A CN 201780028842 A CN201780028842 A CN 201780028842A CN 109152773 A CN109152773 A CN 109152773A
Authority
CN
China
Prior art keywords
nicotine
cannabidiol
pharmaceutical composition
dosage form
smokeless tobacco
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201780028842.XA
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English (en)
Chinese (zh)
Inventor
琼尼尔·R·威廉斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CV Sciences Inc
Original Assignee
CV Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CV Sciences Inc filed Critical CV Sciences Inc
Publication of CN109152773A publication Critical patent/CN109152773A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201780028842.XA 2016-05-16 2017-05-02 用于治疗无烟烟草成瘾的含有大麻二酚和尼古丁的药物制剂 Pending CN109152773A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662336990P 2016-05-16 2016-05-16
US62/336,990 2016-05-16
US15/426,617 2017-02-07
US15/426,617 US10653639B2 (en) 2016-05-16 2017-02-07 Pharmaceutical formulations containing cannabidiol and nicotine for treating smokeless tobacco addiction
PCT/US2017/030558 WO2017200740A1 (en) 2016-05-16 2017-05-02 Pharmaceutical formulations containing cannabidiol and nicotine for treating smokeless tobacco addiction

Publications (1)

Publication Number Publication Date
CN109152773A true CN109152773A (zh) 2019-01-04

Family

ID=60297254

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780028842.XA Pending CN109152773A (zh) 2016-05-16 2017-05-02 用于治疗无烟烟草成瘾的含有大麻二酚和尼古丁的药物制剂

Country Status (8)

Country Link
US (2) US10653639B2 (enExample)
EP (2) EP3936129A1 (enExample)
JP (2) JP6816167B2 (enExample)
CN (1) CN109152773A (enExample)
AU (2) AU2017267927B2 (enExample)
CA (1) CA3021835C (enExample)
ES (1) ES2898342T3 (enExample)
WO (1) WO2017200740A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110573158A (zh) * 2017-03-13 2019-12-13 制药无限有限责任公司 可供人作为享乐或医疗产品消费的无烟草且无烟的产品以及治疗吸烟成瘾的方法
CN111789881A (zh) * 2019-04-04 2020-10-20 昆明医科大学 一种工业大麻提取物的用途
CN114828825A (zh) * 2019-08-30 2022-07-29 塔克索公司 装载的颗粒、其生产方法及其用途
WO2022241921A1 (zh) * 2021-05-21 2022-11-24 张家港外星人新材料科技有限公司 生物碱与酚反应合成物、雾化液、雾化弹及电子雾化器

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* Cited by examiner, † Cited by third party
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US11166910B2 (en) * 2019-01-25 2021-11-09 Nordiccan A/S Cannabinoid chewing gum with sugar alcohols
US11253473B2 (en) * 2019-03-01 2022-02-22 Nordiccan A/S Method of producing tableted cannabinoid chewing gum

Citations (5)

* Cited by examiner, † Cited by third party
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US20020098264A1 (en) * 1998-11-27 2002-07-25 Cherukuri Subraman R. Medicated chewing gum delivery system for nicotine
WO2010046667A1 (en) * 2008-10-24 2010-04-29 Anna Louise Bullus Composition comprising chewing gum, method for producing the same and use thereof
EP2233134A1 (en) * 2009-03-27 2010-09-29 McNeil AB Multi-portion intra-oral dosage form with organoleptic properties
US20140166208A1 (en) * 2011-06-27 2014-06-19 Iq Tec Switzerland Gmbh Preforming pre-preg
US20140209109A1 (en) * 2013-01-30 2014-07-31 Raymond Louis Larson Smokeless THC and Administration Method Thereof

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US3901248A (en) 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
CA2075517C (en) 1992-04-01 1997-03-11 John Wick Transdermal patch incorporating a polymer film incorporated with an active agent
US5948433A (en) 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
FR2788982B1 (fr) * 1999-02-02 2002-08-02 Synthelabo Compositions pharmaceutiques contenant de la nicotine et leur application dans le sevrage tabagique
US20030159702A1 (en) * 2002-01-21 2003-08-28 Lindell Katarina E.A. Formulation and use manufacture thereof
FI113340B (fi) 2002-02-20 2004-04-15 Tomi Jaervinen Uudet luonnon syklodekstriinin kompleksit
GB0712308D0 (en) 2007-06-25 2007-08-01 Kind Group Ltd An inhalable composition
GB2450753B (en) 2007-07-06 2012-07-18 Gw Pharma Ltd New Pharmaceutical formulation
EP2229158B1 (en) * 2007-12-20 2016-08-10 Fertin Pharma A/S Compressed chewing gum tablet
EP2280687B1 (en) 2008-03-26 2019-02-27 Stichting Sanammad Chewing gum compositions comprising cannabinoids
JP5675650B2 (ja) 2009-01-20 2015-02-25 ロサンゼルス バイオメディカル リサーチ インスティテュート アットハーバー− ユーシーエルエー メディカル センター 向精神薬の働きを向上させるソルビン酸、安息香酸及びその誘導体
CA2751627A1 (en) 2009-02-06 2010-08-12 Egalet Ltd. Pharmaceutical compositions resistant to abuse
US20100247586A1 (en) 2009-03-27 2010-09-30 Andreas Hugerth Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties
US8623332B2 (en) 2011-07-06 2014-01-07 Fertin Pharma A/S Chewing gum having sustained release of nicotine
EP2793849A1 (en) 2011-12-22 2014-10-29 Fertin Pharma A/S Method of releasing nicotine from chewing gum
US20140166028A1 (en) 2012-12-14 2014-06-19 Richard C. Fuisz Enhanced Delivery of Nicotine, THC, Tobacco, Cannabidiol or Base Alkaloid from an Electronic Cigarette or Other Vapor or Smoke Producing Device Through Use of an Absorption Conditioning Unit
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* Cited by examiner, † Cited by third party
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US20020098264A1 (en) * 1998-11-27 2002-07-25 Cherukuri Subraman R. Medicated chewing gum delivery system for nicotine
WO2010046667A1 (en) * 2008-10-24 2010-04-29 Anna Louise Bullus Composition comprising chewing gum, method for producing the same and use thereof
EP2233134A1 (en) * 2009-03-27 2010-09-29 McNeil AB Multi-portion intra-oral dosage form with organoleptic properties
US20140166208A1 (en) * 2011-06-27 2014-06-19 Iq Tec Switzerland Gmbh Preforming pre-preg
US20140209109A1 (en) * 2013-01-30 2014-07-31 Raymond Louis Larson Smokeless THC and Administration Method Thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
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CELIA J.A: "Cannabidiol reduces cigarette consumption in tobacco smokers: Preliminary findings", 《ADDICTIVE BEHAVIORS》 *
ZDENĚK FIŠAR: "Inhibition of monoamine oxidase activity by cannabinoids", 《NAUNYN-SCHMIED ARCH PHARMACOL》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110573158A (zh) * 2017-03-13 2019-12-13 制药无限有限责任公司 可供人作为享乐或医疗产品消费的无烟草且无烟的产品以及治疗吸烟成瘾的方法
CN111789881A (zh) * 2019-04-04 2020-10-20 昆明医科大学 一种工业大麻提取物的用途
CN114828825A (zh) * 2019-08-30 2022-07-29 塔克索公司 装载的颗粒、其生产方法及其用途
WO2022241921A1 (zh) * 2021-05-21 2022-11-24 张家港外星人新材料科技有限公司 生物碱与酚反应合成物、雾化液、雾化弹及电子雾化器

Also Published As

Publication number Publication date
EP3458057A4 (en) 2020-02-05
CA3021835A1 (en) 2017-11-23
CA3021835C (en) 2022-03-22
JP2019514990A (ja) 2019-06-06
US20200230077A1 (en) 2020-07-23
JP2021059575A (ja) 2021-04-15
JP7216697B2 (ja) 2023-02-01
JP6816167B2 (ja) 2021-01-20
ES2898342T3 (es) 2022-03-07
AU2017267927A1 (en) 2018-11-08
AU2020256349B2 (en) 2022-03-31
EP3936129A1 (en) 2022-01-12
EP3458057B1 (en) 2021-09-08
AU2017267927B2 (en) 2020-07-30
AU2020256349A1 (en) 2020-11-12
WO2017200740A1 (en) 2017-11-23
EP3458057A1 (en) 2019-03-27
US11191736B2 (en) 2021-12-07
US10653639B2 (en) 2020-05-19
US20170326126A1 (en) 2017-11-16

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Application publication date: 20190104