CN109106892A - A kind of rheumatic arthritis externally applied ointment and preparation method thereof - Google Patents
A kind of rheumatic arthritis externally applied ointment and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to rheumatic arthritis treatment technology fields, a kind of rheumatic arthritis externally applied ointment is disclosed, including below according to the raw material of parts by weight: 20-40 parts of vaseline, 2-5 parts of salicylic acid, 2-5 parts of Diclofenac, 2-4 parts of Allopurinol, 1-3 parts of borneol, 6-12 parts of polyethylene glycol, 1-2 parts of tramadol, 20-30 parts of safflower, 10-20 parts of Radix Angelicae Sinensis, 5-10 parts of Rhizoma Chuanxiong, 4-8 parts of Chinese ephedra, 5-10 parts of chinaroot greenbrier, 2-6 parts of Rabdosia rubescens, 5-10 parts of polygonum cuspidate, 10-20 parts of Radix Glycyrrhizae.The invention also discloses the preparation methods of the rheumatic arthritis externally applied ointment.Plaster prepared by the present invention can effectively treat rheumatic arthritis, relieve pain under the common mating reaction of various raw materials, and symptom improves obviously, and plaster treatment effect prepared by the present invention is good, uneasy to recur.
Description
Technical field
The present invention relates to rheumatic arthritis treatment technology field, specifically a kind of rheumatic arthritis externally applied ointment and its
Preparation method.
Background technique
Rheumatic arthritis is a kind of common acute or chronic connective tissue inflammation.Usually said rheumatic arthritis
It is one of the main performance of rheumatic fever, clinic is characterized by migrans miserable, the red and swollen, pain in joint and muscle.It is B-mode molten with A group
Hemorrhagic streptococcal infection is related, and the factors such as cold, humidity can induce this disease.Lower limb large joint such as knee joint, ankle-joint most often by
It is tired.Although the disease incidence of rheumatic fever has been remarkably decreased in recent decades, atypia rheumatic fever and chronic rheumatic arthritis are simultaneously
It is non-rare.
Arthralgia is the primary symptom of rheumatic arthritis, and general joint is likely to that pain occurs, but with high point
Section involvement is more common, such as knee joint, ankle-joint, shoulder joint, wrist joint.Symmetry, migrans pain typically are shown as,
And it is showed with red, swollen, hot inflammation.A usual joint symptoms subside, and the symptom in another joint may occur in which also have several again
What a joint was fallen ill simultaneously.
The existing treatment method for rheumatic arthritis is mainly oral drug therapy and operative treatment；Oral drugs
Treatment is not only difficult to eradicate, is easy recurrence, can also cause larger burden to body, and the another fixed risk of operative treatment, expense
It is higher, it is also more painful；Although some external preparations, using relatively easy, therapeutic effect is general, it is used for a long time and is still difficult to
Reach good effect.
Summary of the invention
The purpose of the present invention is to provide a kind of rheumatic arthritis externally applied ointments, to solve to propose in above-mentioned background technique
The problem of.
To achieve the above object, the invention provides the following technical scheme:
A kind of rheumatic arthritis externally applied ointment, including below according to the raw material of parts by weight: 20-40 parts of vaseline, bigcatkin willow
2-5 parts sour, 2-5 parts of Diclofenac, 2-4 parts of Allopurinol, 1-3 parts of borneol, 6-12 parts of polyethylene glycol, 1-2 parts of tramadol, safflower
20-30 parts, it is 10-20 parts of Radix Angelicae Sinensis, 5-10 parts of Rhizoma Chuanxiong, 4-8 parts of Chinese ephedra, 5-10 parts of chinaroot greenbrier, 2-6 parts of Rabdosia rubescens, 5-10 parts of polygonum cuspidate, sweet
It is 10-20 parts careless.
As a further solution of the present invention: including below according to the raw material of parts by weight: 25-35 parts of vaseline, salicylic acid
3-4 parts, 3-4 parts of Diclofenac, 2.5-3.5 parts of Allopurinol, 1.5-2.5 parts of borneol, 8-10 parts of polyethylene glycol, tramadol 1.2-
1.8 parts, 22-28 parts of safflower, 12-18 parts of Radix Angelicae Sinensis, 6-8 parts of Rhizoma Chuanxiong, 5-7 parts of Chinese ephedra, 6-9 parts of chinaroot greenbrier, 3-5 parts of Rabdosia rubescens, polygonum cuspidate
7-9 parts, 12-18 parts of Radix Glycyrrhizae.
As further scheme of the invention: including below according to the raw material of parts by weight: 30 parts of vaseline, salicylic acid
3.5 parts, 3.5 parts of Diclofenac, 3 parts of Allopurinol, 2 parts of borneol, 9 parts of polyethylene glycol, 1.5 parts of tramadol, 25 parts of safflower, Radix Angelicae Sinensis 15
Part, 7 parts of Rhizoma Chuanxiong, 6 parts of Chinese ephedra, 8 parts of chinaroot greenbrier, 4 parts of Rabdosia rubescens, 8 parts of polygonum cuspidate, 15 parts of Radix Glycyrrhizae.
The preparation method of the rheumatic arthritis externally applied ointment, steps are as follows:
1) it is put into container after cleaning safflower, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Chinese ephedra, chinaroot greenbrier, Rabdosia rubescens, polygonum cuspidate, Radix Glycyrrhizae, smashs to pieces, add
Enter the ethanol solution of 3-5 times of parts by weight, impregnates 12-24h, then pass through the ultrasonic wave assisted extraction 10-20min of 20-30KHz, obtain
Obtain mixture；
2) distilled water of 8-10 times of parts by weight of traditional Chinese medicinal material raw materials is added in the mixture obtained to step 1), is used again after boiling
It is cooked by slow fire 1-2h, is filtered while hot, obtains filtered fluid after cooling；
3) add Diclofenac, Allopurinol, borneol, polyethylene glycol, tramadol in the filtered fluid obtained to step 2), with 800-
1000r/min revolving speed stirs 5-10min, obtains admixing medical solutions；
4) admixing medical solutions obtained to step 3) are concentrated, and vaseline, bigcatkin willow are added into the admixing medical solutions after concentration
Acid stirs 3-5min with 100-200r/min revolving speed, and discharging obtains paste；
5) by step 4) obtain paste with irradiation dose be 6.0-8.0KG isotope Co 60 generate radiated by gamma-ray
Sterilizing.
As further scheme of the invention: ethanol solution concentration described in step 1) is 60-80%.
As further scheme of the invention: the time of the sterilizing of radiated by gamma-ray described in step 5) is 5-
10min。
Application of the above-mentioned plaster in preparation treatment bone and joint diseases drug.
Compared with prior art, the beneficial effects of the present invention are:
Plaster prepared by the present invention can effectively treat rheumatic arthritis under the common mating reaction of various raw materials,
It relieves pain, symptom improves obviously, and plaster treatment effect prepared by the present invention is good, uneasy to recur；The present invention is by using all
For intellectual circle as intermediate medium, plaster is easy to use, and drug effect is easily absorbed by the body, not easily runs off, and will not cause to human body
Burden.
Specific embodiment
Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described,
Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention
Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all
Belong to the scope of protection of the invention.
Embodiment 1
A kind of rheumatic arthritis externally applied ointment, including below according to the raw material of parts by weight: 20 parts of vaseline, salicylic acid 2
Part, 2 parts of Diclofenac, 2 parts of Allopurinol, 1 part of borneol, 6 parts of polyethylene glycol, 1 part of tramadol, 20 parts of safflower, 10 parts of Radix Angelicae Sinensis, Rhizoma Chuanxiong
5 parts, 4 parts of Chinese ephedra, 5 parts of chinaroot greenbrier, 2 parts of Rabdosia rubescens, 5 parts of polygonum cuspidate, 10 parts of Radix Glycyrrhizae.
In the present embodiment, the preparation method of the rheumatic arthritis externally applied ointment, steps are as follows:
1) it is put into container after cleaning safflower, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Chinese ephedra, chinaroot greenbrier, Rabdosia rubescens, polygonum cuspidate, Radix Glycyrrhizae, smashs to pieces, add
Enter the ethanol solution of 3 times of parts by weight, impregnates 12h, then pass through the ultrasonic wave assisted extraction 10min of 20KHz, obtain mixture；
2) distilled water of 8 times of parts by weight of traditional Chinese medicinal material raw materials is added in the mixture obtained to step 1), again with text after boiling
Fire decocts 1h, filters while hot, obtains filtered fluid after cooling；
3) add Diclofenac, Allopurinol, borneol, polyethylene glycol, tramadol in the filtered fluid obtained to step 2), with
800r/min revolving speed stirs 5min, obtains admixing medical solutions；
4) admixing medical solutions obtained to step 3) are concentrated, and vaseline, bigcatkin willow are added into the admixing medical solutions after concentration
Acid stirs 3min with 100r/min revolving speed, and discharging obtains paste；
5) paste that step 4) obtains is gone out with the radiated by gamma-ray that irradiation dose is the generation of 6.0KG isotope Co 60
Bacterium.
Wherein, ethanol solution concentration described in step 1) is 60%.
Wherein, the time of the sterilizing of radiated by gamma-ray described in step 5) is 5min.
Embodiment 2
A kind of rheumatic arthritis externally applied ointment, including below according to the raw material of parts by weight: 25 parts of vaseline, salicylic acid 3
Part, 3 parts of Diclofenac, 2.5 parts of Allopurinol, 1.5 parts of borneol, 8 parts of polyethylene glycol, 1.2 parts of tramadol, 28 parts of safflower, Radix Angelicae Sinensis 18
Part, 8 parts of Rhizoma Chuanxiong, 7 parts of Chinese ephedra, 9 parts of chinaroot greenbrier, 5 parts of Rabdosia rubescens, 9 parts of polygonum cuspidate, 18 parts of Radix Glycyrrhizae.
In the present embodiment, the preparation method of the rheumatic arthritis externally applied ointment, steps are as follows:
1) it is put into container after cleaning safflower, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Chinese ephedra, chinaroot greenbrier, Rabdosia rubescens, polygonum cuspidate, Radix Glycyrrhizae, smashs to pieces, add
Enter the ethanol solution of 4 times of parts by weight, impregnates 18h, then pass through the ultrasonic wave assisted extraction 15min of 25KHz, obtain mixture；
2) distilled water of 9 times of parts by weight of traditional Chinese medicinal material raw materials is added in the mixture obtained to step 1), again with text after boiling
Fire decocts 1.5h, filters while hot, obtains filtered fluid after cooling；
3) add Diclofenac, Allopurinol, borneol, polyethylene glycol, tramadol in the filtered fluid obtained to step 2), with
900r/min revolving speed stirs 7min, obtains admixing medical solutions；
4) admixing medical solutions obtained to step 3) are concentrated, and vaseline, bigcatkin willow are added into the admixing medical solutions after concentration
Acid stirs 4min with 150r/min revolving speed, and discharging obtains paste；
5) paste that step 4) obtains is gone out with the radiated by gamma-ray that irradiation dose is the generation of 7.0KG isotope Co 60
Bacterium.
Wherein, ethanol solution concentration described in step 1) is 70%.
Wherein, the time of the sterilizing of radiated by gamma-ray described in step 5) is 8min.
Embodiment 3
A kind of rheumatic arthritis externally applied ointment, including below according to the raw material of parts by weight: 30 parts of vaseline, salicylic acid
3.5 parts, 3.5 parts of Diclofenac, 3 parts of Allopurinol, 2 parts of borneol, 9 parts of polyethylene glycol, 1.5 parts of tramadol, 25 parts of safflower, Radix Angelicae Sinensis 15
Part, 7 parts of Rhizoma Chuanxiong, 6 parts of Chinese ephedra, 8 parts of chinaroot greenbrier, 4 parts of Rabdosia rubescens, 8 parts of polygonum cuspidate, 15 parts of Radix Glycyrrhizae
In the present embodiment, the preparation method of the rheumatic arthritis externally applied ointment, steps are as follows:
1) it is put into container after cleaning safflower, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Chinese ephedra, chinaroot greenbrier, Rabdosia rubescens, polygonum cuspidate, Radix Glycyrrhizae, smashs to pieces, add
Enter the ethanol solution of 4 times of parts by weight, impregnates 18h, then pass through the ultrasonic wave assisted extraction 15min of 25KHz, obtain mixture；
2) distilled water of 9 times of parts by weight of traditional Chinese medicinal material raw materials is added in the mixture obtained to step 1), again with text after boiling
Fire decocts 1.5h, filters while hot, obtains filtered fluid after cooling；
3) add Diclofenac, Allopurinol, borneol, polyethylene glycol, tramadol in the filtered fluid obtained to step 2), with
900r/min revolving speed stirs 7min, obtains admixing medical solutions；
4) admixing medical solutions obtained to step 3) are concentrated, and vaseline, bigcatkin willow are added into the admixing medical solutions after concentration
Acid stirs 4min with 150r/min revolving speed, and discharging obtains paste；
5) paste that step 4) obtains is gone out with the radiated by gamma-ray that irradiation dose is the generation of 7.0KG isotope Co 60
Bacterium.
Wherein, ethanol solution concentration described in step 1) is 70%.
Wherein, the time of the sterilizing of radiated by gamma-ray described in step 5) is 8min.
Embodiment 4
A kind of rheumatic arthritis externally applied ointment, including below according to the raw material of parts by weight: 35 parts of vaseline, salicylic acid 4
Part, 4 parts of Diclofenac, 3.5 parts of Allopurinol, 2.5 parts of borneol, 10 parts of polyethylene glycol, 1.8 parts of tramadol, 22 parts of safflower, Radix Angelicae Sinensis 12
Part, 6 parts of Rhizoma Chuanxiong, 5 parts of Chinese ephedra, 6 parts of chinaroot greenbrier, 3 parts of Rabdosia rubescens, 7 parts of polygonum cuspidate, 12 parts of Radix Glycyrrhizae.
In the present embodiment, the preparation method of the rheumatic arthritis externally applied ointment, steps are as follows:
1) it is put into container after cleaning safflower, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Chinese ephedra, chinaroot greenbrier, Rabdosia rubescens, polygonum cuspidate, Radix Glycyrrhizae, smashs to pieces, add
Enter the ethanol solution of 4 times of parts by weight, impregnates 18h, then pass through the ultrasonic wave assisted extraction 15min of 25KHz, obtain mixture；
2) distilled water of 9 times of parts by weight of traditional Chinese medicinal material raw materials is added in the mixture obtained to step 1), again with text after boiling
Fire decocts 1.5h, filters while hot, obtains filtered fluid after cooling；
3) add Diclofenac, Allopurinol, borneol, polyethylene glycol, tramadol in the filtered fluid obtained to step 2), with
900r/min revolving speed stirs 7min, obtains admixing medical solutions；
4) admixing medical solutions obtained to step 3) are concentrated, and vaseline, bigcatkin willow are added into the admixing medical solutions after concentration
Acid stirs 4min with 150r/min revolving speed, and discharging obtains paste；
5) paste that step 4) obtains is gone out with the radiated by gamma-ray that irradiation dose is the generation of 7.0KG isotope Co 60
Bacterium.
Wherein, ethanol solution concentration described in step 1) is 70%.
Wherein, the time of the sterilizing of radiated by gamma-ray described in step 5) is 8min.
Embodiment 5
A kind of rheumatic arthritis externally applied ointment, including below according to the raw material of parts by weight: 40 parts of vaseline, salicylic acid 5
Part, 5 parts of Diclofenac, 4 parts of Allopurinol, 3 parts of borneol, 12 parts of polyethylene glycol, 2 parts of tramadol, 30 parts of safflower, 20 parts of Radix Angelicae Sinensis, river
10 parts of rhizome of chuanxiong, 8 parts of Chinese ephedra, 10 parts of chinaroot greenbrier, 6 parts of Rabdosia rubescens, 10 parts of polygonum cuspidate, 20 parts of Radix Glycyrrhizae.
In the present embodiment, the preparation method of the rheumatic arthritis externally applied ointment, steps are as follows:
1) it is put into container after cleaning safflower, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Chinese ephedra, chinaroot greenbrier, Rabdosia rubescens, polygonum cuspidate, Radix Glycyrrhizae, smashs to pieces, add
Enter the ethanol solution of 5 times of parts by weight, impregnate for 24 hours, then pass through the ultrasonic wave assisted extraction 20min of 30KHz, obtains mixture；
2) distilled water of 10 times of parts by weight of traditional Chinese medicinal material raw materials is added in the mixture obtained to step 1), again with text after boiling
Fire decocts 2h, filters while hot, obtains filtered fluid after cooling；
3) add Diclofenac, Allopurinol, borneol, polyethylene glycol, tramadol in the filtered fluid obtained to step 2), with
1000r/min revolving speed stirs 10min, obtains admixing medical solutions；
4) admixing medical solutions obtained to step 3) are concentrated, and vaseline, bigcatkin willow are added into the admixing medical solutions after concentration
Acid stirs 5min with 200r/min revolving speed, and discharging obtains paste；
5) paste that step 4) obtains is gone out with the radiated by gamma-ray that irradiation dose is the generation of 8.0KG isotope Co 60
Bacterium.
Wherein, ethanol solution concentration described in step 1) is 80%.
Wherein, the time of the sterilizing of radiated by gamma-ray described in step 5) is 10min.
Comparative example 1
Compared with Example 3, Allopurinol is free of, other are same as Example 3.
Comparative example 2
Compared with Example 3, chinaroot greenbrier is free of, other are same as Example 3.
Comparative example 3
Compared with Example 3, Allopurinol and chinaroot greenbrier are free of, other are same as Example 3.
Plaster prepared by embodiment 1-5 and comparative example 1-3 is tested for the property, test result is as shown in table 1.
Test basis: choosing 80 rheumatoid arthritis patients, and age, gender are random, one group of every 10 people, uses this respectively
Invention ointment 3 months uses 1 time, application method daily: ointment being applied to joint after cleaning before sleeping, uses gauze bondage, 8-
Gauze is removed after 10h, wiping cleans up.
Efficacy assessment standard:
Effective: feeling of pain subsides substantially, and symptom disappears substantially.
Effective: feeling of pain is alleviated, and symptom improves unobvious.
Invalid: feeling of pain is not alleviated, and symptom is without improvement.
Table 1
It, can from can be seen that plaster prepared by the present invention in result above under the common mating reaction of various raw materials
Effectively treatment rheumatic arthritis, relieves pain, and symptom improves obviously, and plaster treatment effect prepared by the present invention is good, is not easy
Recurrence.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims
Variation is included within the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiments being understood that.
Claims (7)
1. a kind of rheumatic arthritis externally applied ointment, which is characterized in that including below according to the raw material of parts by weight: vaseline 20-
40 parts, 2-5 parts of salicylic acid, 2-5 parts of Diclofenac, 2-4 parts of Allopurinol, 1-3 parts of borneol, 6-12 parts of polyethylene glycol, tramadol 1-2
Part, 20-30 parts of safflower, 10-20 parts of Radix Angelicae Sinensis, 5-10 parts of Rhizoma Chuanxiong, 4-8 parts of Chinese ephedra, 5-10 parts of chinaroot greenbrier, 2-6 parts of Rabdosia rubescens, polygonum cuspidate 5-
10 parts, 10-20 parts of Radix Glycyrrhizae.
2. rheumatic arthritis externally applied ointment according to claim 1, which is characterized in that including below according to parts by weight
Raw material: 25-35 parts of vaseline, 3-4 parts of Diclofenac, 2.5-3.5 parts of Allopurinol, 1.5-2.5 parts of borneol, gathers 3-4 parts of salicylic acid
8-10 parts of ethylene glycol, 1.2-1.8 parts of tramadol, 22-28 parts of safflower, 12-18 parts of Radix Angelicae Sinensis, 6-8 parts of Rhizoma Chuanxiong, 5-7 parts of Chinese ephedra, chinaroot greenbrier
6-9 parts, 3-5 parts of Rabdosia rubescens, 7-9 parts of polygonum cuspidate, 12-18 parts of Radix Glycyrrhizae.
3. rheumatic arthritis externally applied ointment according to claim 2, which is characterized in that including below according to parts by weight
Raw material: 30 parts of vaseline, 3.5 parts of salicylic acid, 3.5 parts of Diclofenac, 3 parts of Allopurinol, 2 parts of borneol, 9 parts of polyethylene glycol, bent horse
Piece 1.5 parts, 25 parts of safflower, 15 parts of Radix Angelicae Sinensis, 7 parts of Rhizoma Chuanxiong, 6 parts of Chinese ephedra, 8 parts of chinaroot greenbrier, 4 parts of Rabdosia rubescens, 8 parts of polygonum cuspidate, 15 parts of Radix Glycyrrhizae.
4. a kind of preparation method of rheumatic arthritis externally applied ointment a method according to any one of claims 1-3, which is characterized in that packet
Include following steps:
1) it is put into container, smashs to pieces after cleaning safflower, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Chinese ephedra, chinaroot greenbrier, Rabdosia rubescens, polygonum cuspidate, Radix Glycyrrhizae, 3- is added
The ethanol solution of 5 times of parts by weight impregnates 12-24h, then passes through the ultrasonic wave assisted extraction 10-20min of 20-30KHz, is mixed
Close object；
2) distilled water of 8-10 times of parts by weight of traditional Chinese medicinal material raw materials is added in the mixture obtained to step 1), uses mild fire after boiling again
1-2h is decocted, is filtered while hot, obtains filtered fluid after cooling；
3) add Diclofenac, Allopurinol, borneol, polyethylene glycol, tramadol in the filtered fluid obtained to step 2), with 800-
1000r/min revolving speed stirs 5-10min, obtains admixing medical solutions；
4) admixing medical solutions obtained to step 3) are concentrated, and vaseline, salicylic acid are added into the admixing medical solutions after concentration, with
100-200r/min revolving speed stirs 3-5min, and discharging obtains paste；
5) paste that step 4) obtains is gone out with the radiated by gamma-ray that irradiation dose is the generation of 6.0-8.0KG isotope Co 60
Bacterium.
5. the preparation method of rheumatic arthritis externally applied ointment according to claim 4, which is characterized in that institute in step 1)
The ethanol solution concentration stated is 60-80%.
6. the preparation method of rheumatic arthritis externally applied ointment according to claim 4, which is characterized in that institute in step 5)
The time for the radiated by gamma-ray sterilizing stated is 5-10min.
7. a kind of application of plaster a method according to any one of claims 1-3 in preparation treatment bone and joint diseases drug.
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| CN1232672A (en) * | 1998-03-17 | 1999-10-27 | 刘泽华 | Compound arthritis curing capsule |
| CN102144989A (en) * | 2011-04-28 | 2011-08-10 | 天津瑞德药业有限公司 | Preparation method of hydrogel cataplasm and prepared cataplasm with effect of relieving swelling and pains |
| CN103251716A (en) * | 2013-05-21 | 2013-08-21 | 四川厚生天佐药业有限公司 | Swelling-diminishing pain-erasing ointment and preparation method thereof |
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2018
- 2018-10-26 CN CN201811258435.0A patent/CN109106892A/en not_active Withdrawn
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|---|---|---|---|---|
| CN1232672A (en) * | 1998-03-17 | 1999-10-27 | 刘泽华 | Compound arthritis curing capsule |
| CN102144989A (en) * | 2011-04-28 | 2011-08-10 | 天津瑞德药业有限公司 | Preparation method of hydrogel cataplasm and prepared cataplasm with effect of relieving swelling and pains |
| CN103251716A (en) * | 2013-05-21 | 2013-08-21 | 四川厚生天佐药业有限公司 | Swelling-diminishing pain-erasing ointment and preparation method thereof |
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| 包文胜: "活血化瘀法在治疗疑难病中的应用", 《中医药临床杂志》 * |
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