CN109045141A - Chinese medicine composition, preparation and application - Google Patents

Chinese medicine composition, preparation and application Download PDF

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Publication number
CN109045141A
CN109045141A CN201811278776.4A CN201811278776A CN109045141A CN 109045141 A CN109045141 A CN 109045141A CN 201811278776 A CN201811278776 A CN 201811278776A CN 109045141 A CN109045141 A CN 109045141A
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weight
parts
chinese medicine
medicine composition
application
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闫癸江
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Insects & Arthropods (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine composition, by the world blueness of 1.5 parts by weight red, 1 parts by weight Impatientis, the perilla leaf of 1 parts by weight, the carpet bugle of 1.5 parts by weight, the evodia rutaecarpa of 2.5 parts by weight, the achene of Siberian cocklebur of 1.5 parts by weight, the Bailey Myospalax Born of 2 parts by weight, the silky ant of 1.5 parts by weight, 1.5 parts by weight gentianae macrophyllae form.

Description

Chinese medicine composition, preparation and application
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition, preparation and application.
Background technique
Cervical vertebra inflammation is to refer to the clinical symptoms and sign showed after cervical spine lesion.It is a kind of frequently-occurring disease, in 40-60 Year is high incidence age, and disease incidence is 100% after 70 years old.But develop now in gradually rejuvenation.The generation of cervical spondylosis with Acute and chronic injury, occupational characteristic and the constitution of individual of cervical vertebra include that inherited trait has close relationship, furthermore personal life Habit and eating habit have certain influence.The treatment of cervical vertebra inflammation is a comprehensive therapeutic process, and daily protection is pre- Prevent extremely important.
Arthritis (arthritis) refers to generation in human synovial and its surrounding tissue, by inflammation, infection, degeneration, wound Or inflammatory disease caused by other factors, tens of kinds can be divided into.The arthritic in China has 100,000,000 or more, and number is continuous Increase.Clinical manifestation is the red, swollen, hot of joint, pain, dysfunction and joint deformity, and serious person leads to joint deformity, influences to suffer from Person's quality of life.Half suffers from osteoarthritis, 90% women and 80% in over-65s crowd in China 50 years old or more crowd according to statistics Male suffers from osteoarthritis.The illness rate in China is 0.34%~0.36%, and serious person's service life about shortens 10~15 years.
The protrasion of the lumbar intervertebral disci is relatively conventional one of illness, is primarily due to lumber ertebral disc each section (nucleus pulposus, fiber Ring and cartilage plate), especially nucleus pulposus, after having different degrees of degenerative change, under the action of external force factor, the fibre of interverbebral disc Ring breakage is tieed up, nucleus pulposus in rear or intraspinal tube, causes adjacent spinal nerve root to be pierced from rupture place prominent (or abjection) Swash or oppress, to generate flank pain.
Ointment or plaster now on the market mainly uses activating microcirculation and removing stasis medicinal and analgesic treatment means for joint part It is treated, but it due to being only limitted to activating microcirculation and removing stasis medicinal, therapeutic domain is smaller, chronic cervical vertebra inflammation therapeutic effect is very slow Or it is difficult to treat, protrusion of lumber intervertebral disc is difficult to control.
Summary of the invention
It is an object of that present invention to provide Chinese medicine compositions, can control arthritis, cervical vertebra inflammation and protrusion of lumber intervertebral disc It treats.
To achieve the goals above, the technical solution adopted by the present invention is as follows:
Chinese medicine composition, red, 1 parts by weight Impatientis, the perilla leaf of 1 parts by weight, 1.5 weight by the world blueness of 1.5 parts by weight Part carpet bugle, the evodia rutaecarpa of 2.5 parts by weight, the achene of Siberian cocklebur of 1.5 parts by weight, the Bailey Myospalax Born of 2 parts by weight, 1.5 parts by weight it is black Ant, 1.5 parts by weight gentianae macrophyllae composition.
Chinese materia medica preparation, the externally applied ointment being prepared by above-mentioned Chinese medicine composition.
Above-mentioned Chinese medicine composition is applied in the drug for the treatment of of arthritis.
Above-mentioned Chinese medicine composition is applied in the drug for the treatment of cervical vertebra inflammation.
Above-mentioned Chinese medicine composition is applied in the drug for the treatment of protrusion of lumber intervertebral disc.
Above-mentioned Chinese materia medica preparation the preparation method comprises the following steps: above-mentioned a variety of drugs are purified, purify the medical fluid for 98%, then It is mixed according to said ratio.
The use process of above-mentioned Chinese materia medica preparation are as follows: after mixing the mixed liquor of above-mentioned a variety of drugs with ethyl alcohol, drip in gauze On be applied with.In use, ethyl alcohol is added is to generate heat, urging makes the efficacy of a drug be rapidly reached affected part.
In the present invention,
It is reddish blackly red in the present invention, there is the effect of blood circulation, eliminating stasis to subdue swelling;Impatientis has the function of wind-damp dispelling, promoting blood circulation and stopping pain Effect;Perilla leaf plays the role of anti-inflammation and sterilization;Carpet bugle refreshing and detoxicating, cool blood detumescence, being capable of anti-bacteria and anti-virus;Evodia rutaecarpa analgesic, It is antibacterial, antiviral.
In the present invention, for it is arthritic treatment mainly utilize scattered silt stagnant gas blood, while can anti-inflammatory analgesic, to reach To arthritic treatment is directed to well, also have on the market now certainly with for arthritic Chinese medicine ointment, but it is of the invention Compared to ointment now on the market, curative effect is better, and faster, and preparation method of the invention can reduce the loss of drug effect, from And make that curative effect is better faster.
It is mainly the cooperation promotion office of reddish blackly red and Impatientis, gentianae macrophyllae for curing protrusion of lumbar intervertebral disc in the present invention The metabolism that portion's circulating function and recovery are locally obstructed, enables occupy-place tissue to absorb and drain, therefore between treatment lumbar vertebrae Disk protrudes good effect, and perilla leaf, carpet bugle and evodia rutaecarpa are primarily to eliminate lumber ertebral disc pain, while to lumbar vertebrae Inflammation caused by disk is prominent is treated, and carpet bugle is other than analgesic, additionally it is possible to so that Impatientis and reddish black red energy It is enough to eliminate Nucleus pulposus phenomenon faster, so that curative effect is faster.
In the present invention, for cervical vertebra inflammation, reddish blackly red and carpet bugle can have good treatment to cervical vertebra inflammation caused by exogenous disease Effect, reddish blackly red and Impatientis partner treatment can have good curative effect to it;And cervical vertebra inflammation main purpose caused by wound is Blood stasis gas is removed, therefore the present invention also has a good therapeutic effect, and chronic cervical vertebra inflammation is due to being that prolonged strain causes, because This needs above-mentioned composition to promote metabolic cycles, and tough sclerotin removes cervical vertebrae hyperosteogeny, to treat chronic cervical vertebra inflammation And its caused pain.
Certainly, since composition of the invention can remove extravasated blood silt gas, also there is good therapeutic effect to strain.
The medication amount that the present invention uses is few, therefore low in cost, on this basis, also has very well to above-mentioned a variety of diseases Curative effect, while it is quick.
The application method of above-mentioned traditional Chinese medicine plaster are as follows: by plaster in pain affected part, every one patch of 15h replacement.
Specific embodiment
The invention discloses Chinese medicine composition, preparation and application, those skilled in the art can use for reference present disclosure, suitably Improve realization of process parameters.In particular, it should be pointed out that all similar substitutions and modifications are for a person skilled in the art It will be apparent that they are considered as being included in the present invention.Method and application of the invention is carried out by preferred embodiment Description, related personnel obviously can not depart from the content of present invention, in spirit and scope to method described herein and application into Row change or appropriate changes and combinations, carry out implementation and application the technology of the present invention.
Embodiment
Traditional Chinese medicine plaster, by red 15 grams reddish blackly, 10 grams of Impatientis, 10 grams of perilla leaf, 15 grams of carpet bugle, 25 grams of evodia rutaecarpa, 15 grams of the achene of Siberian cocklebur, 20 grams of Bailey Myospalax Born, 15 grams of silky ant, 15 grams of gentianae macrophyllae be prepared.
Experimental example 1
By arthritis, 500 people of clinical trial number, wherein 458 people's pain completely disappear in 5 patches, remaining 42 people are in 15 patches Pain completely disappears, this is because embodiment has good anti-inflammatory and removes the effect of silt gas, and it is mostly scorching that arthritis is prominent Disease and intra-articular qi and blood stasis cause, and therefore, effect is ideal.
Experimental example 2
1. chronic cervical vertebra inflammation, 500 people of clinical trial number, wherein 221 people cure 20 or so, and 152 people control in 35 patch left and right More, 127 people cure more than 45 patches.
Embodiment 3
Protrusion of lumber intervertebral disc, 500 people of clinical trial number, wherein 161 people cure in 20 patch left and right, 232 people control in 35 patch left and right More, 107 people cure in 45 patch left and right.

Claims (5)

1. Chinese medicine composition, which is characterized in that by the world blueness of 1.5 parts by weight red, 1 parts by weight Impatientis, 1 parts by weight purple Perilla leaf, the carpet bugle of 1.5 parts by weight, the evodia rutaecarpa of 2.5 parts by weight, the achene of Siberian cocklebur of 1.5 parts by weight, 2 parts by weight Bailey Myospalax Born, The gentianae macrophyllae composition of the silky ant of 1.5 parts by weight, 1.5 parts by weight.
2. Chinese materia medica preparation, which is characterized in that the plaster being prepared by Chinese medicine composition described in claim 1.
3. application of the Chinese medicine composition as described in claim 1 in the drug for the treatment of of arthritis.
4. application of the Chinese medicine composition as described in claim 1 in the drug for the treatment of cervical vertebra inflammation.
5. application of the Chinese medicine composition as described in claim 1 in the drug for treating inflammation caused by protrusion of lumber intervertebral disc.
CN201811278776.4A 2018-10-30 2018-10-30 Chinese medicine composition, preparation and application Pending CN109045141A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811278776.4A CN109045141A (en) 2018-10-30 2018-10-30 Chinese medicine composition, preparation and application

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Application Number Priority Date Filing Date Title
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1207944A (en) * 1998-08-31 1999-02-17 李方瑞 Rheumatism capsule
CN1342462A (en) * 2000-09-08 2002-04-03 何兴峰 Composite medicine for treating rheumatoid arthritis
CN1923230A (en) * 2005-09-02 2007-03-07 王凯 Medicine for treating rheumatism and rheumatoid disease, and its preparation method
CN103316307A (en) * 2008-04-03 2013-09-25 段云平 Chinese herbal medicine for external use by fumigating and immersing-rheumatism and arthralgia medicine
CN106728347A (en) * 2016-11-17 2017-05-31 魏聆 A kind of FENGSHI YE and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1207944A (en) * 1998-08-31 1999-02-17 李方瑞 Rheumatism capsule
CN1342462A (en) * 2000-09-08 2002-04-03 何兴峰 Composite medicine for treating rheumatoid arthritis
CN1923230A (en) * 2005-09-02 2007-03-07 王凯 Medicine for treating rheumatism and rheumatoid disease, and its preparation method
CN103316307A (en) * 2008-04-03 2013-09-25 段云平 Chinese herbal medicine for external use by fumigating and immersing-rheumatism and arthralgia medicine
CN106728347A (en) * 2016-11-17 2017-05-31 魏聆 A kind of FENGSHI YE and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
国家药典委员会编: "《中华人民共和国药典 临床用药须知 中药成方制剂卷 2010年版》", 30 April 2011, 中国医药科技出版社 *
李艳青等: "《中医学专业知识》", 31 January 2013, 世界图书出版公司北京公司 *
梅全喜: "《现代中药药理与临床应用手册》", 31 October 2008, 中国中医药出版社 *

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Application publication date: 20181221

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