CN109010113A - A kind of composition that repairing sensitive skin and its application - Google Patents

Abstract

It by weight percent include the deacetylated carboxymethyl chitosan solution of the ultimate attainment reparation peptide of 0.5-10.0%, -8 solution of palmityl tripeptides of 0.5-10.0% and 0.5-10.0% the present invention provides a kind of composition for repairing sensitive skin and its application, the composition；The present invention, which passes through, has effects that the active constituent repaired has obtained the formula of this composition after multiple composite test by screening layer by layer, each component is synergistic, skin physiology function is adjusted, the metabolism of skin histology is improved, skin is repaired and reaches best physiological status；Present invention process is simple, it can be achieved that industrialization large-scale production, can bring good economic benefit for enterprise, have wide prospect.

Description

A kind of composition that repairing sensitive skin and its application

Technical field

The present invention relates to cosmetic field, a kind of composition for repairing sensitive skin and its application are related generally to.

Background technique

In recent years, with the increase of people's life and work pressure, the external environments such as atmosphere pollution, PM2.5 are severe to be added Acute and incorrect skin care mode, causes skin hypersensitivity crowd to sharply increase, and it is strong that skin sensitivity has become the influence mankind The social concern of health.Adult more than 50% lives through the process of sensitive, and the common feature of sensitive is Existing shouting pain, tight feeling, scorching hot, itch and adjoint inflammation redness symptom.Sensory nerve fibre rich in human skin, These nerve fibres can be aware of the situation of skin by central nervous system at any time, and pierce to various chemical reactions, heat, physiology Swash and makes a response.Sensitive skin is generally considered in body and interacts with extraneous factor, cause skin barrier function by Damage, transepidermal water, which scatters and disappears, to be increased, and penetrates into environmental stimuli object easily, leads to the incoming enhancing of dermal sensation nerve signal, tolerance threshold It reduces, excessive to the stimulate the reaction that the external world is faint, activation cutaneous immunisation reaction, vascular reactivity enhancing leads to blood vessel extension, inflammation There is red and swollen, telangiectasis, consciously there is all kinds of skin uncomfortable diseases of tight feeling, scorching hot, itch etc. in disease cellular infiltration, skin Shape.For these problems, also occur many declare with the various cosmetics for repairing sensitive skin immediately on the market.This kind of In product, what is be commonly used is to declare the plant extract with effect of releiving.

106176274A discloses a kind of peptide composition with antiallergic effect, and all kinds of polypeptides are as follows: (1), selecting One or more following polypeptides of skin tolerance threshold, including but not limited to acetyl group four are improved from the cutaneous nerve source reaction of reduction Peptide -15；(2), including but not limited to brown selected from the one or more following polypeptides for reducing inflammatory mediator generation reduction inflammatory reaction Palmitic acid acyl tripeptides -8, acetyl group tetrapeptide -33, acetyl group tetrapeptide -40, -1 cetyl of acetyl group dipeptides, acetyl group hexapeptide -49；Wherein Above each polypeptide moiety mass concentration is 0.0001%-5%.106890122A disclose a kind of skin releive Itch Stopping Gel and its Preparation method, the invention with dendrobium candidum extracting solution and carboxymethylchitosan for main effectiveness substance, and with thickener, Moisturizer, solubilizer etc. carry out reasonable compatibility, prepare and releive antipruritic and moisturizing effect gel with skin.106726668A Disclose a kind of polypeptide liposome raw material used in cosmetics, comprising by carnosine, palmityl tripeptides 1, palmityl tetrapeptide 7, Matrixyl 4, acetyl group hexapeptide 8, lecithin (and) propylene glycol and two C1213 alcohol malates, be used for sensibility skin, tightly It causes skin and repairs wrinkle functional cosmetics, reach and releive and improve skin sensitivity.107823092A discloses a kind of anti-ageing Old peptide composition, preparation method and application, with the mass fraction of peptide composition for 100, peptide composition is by following heavy The group of amount part is grouped as: 1-10 parts of palmityl tetrapeptides -7,1-10 parts of palmityl tripeptides -5,1-10 parts of acetyl group tetrapeptides -5,5-15 Part palmitoyl oligopeptide, 5-20 parts of oat peptides, 5-20 parts of Wild soybean peptides, 2-15 parts of dried tremella extracts, 0.05-0.5 parts of stem cells point Secrete the water of the factor and surplus.105147534A discloses a kind of peptide composition for skin repair, includes: (1), having There is the polypeptide for promoting skin collagen nucleus formation, selected from one or more of following polypeptides, including but not limited to: palmityl three Peptide 1, tripeptides 1, Matrixyl 3, tetrapeptide 21, palmityl hexapeptide 6, palmityl tripeptides 5, acetyl group tetrapeptide 11, myristoyl pentapeptide 11, myristoyl hexapeptide 4, myristoyl octapeptide 1, hexapeptide 3, pentapeptide 31, copper peptide；(2) have and promote the generation of skin Laminin lens Polypeptide, with the polypeptide for promoting dermal elastin and with make up proteoglycan missing one of polypeptide, two kinds or It is three kinds, described that there is the polypeptide for promoting skin Laminin lens to generate to be selected from one or more of following polypeptides, including but not limited to: Hexapeptide 8, hexapeptide 9, hexapeptide 10, hexanoyl tetrapeptide 3, heptapeptide, palmityl dipeptides 5, diaminobutyryl hydroxyl threonine, palmityl dipeptides 6 diamino hydroxybutyric acids；The polypeptide that there is promotion dermal elastin, including but not limited to: palmitoyl oligopeptide Pal VGVAPG；It is described have make up the one or more of following polypeptides of proteoglycan, including but not limited to: 10 citrulling of tripeptides, acetyl Base tetrapeptide 9, acetyl tetrapeptide 11；Wherein, the concentration of each component is 0.01ppm -50000ppm (w/w), and solvent is preferably Water.105232352B provides a kind of for the anti-wrinkle polypeptide complex of eye, percentage, by following components group At: the acetyl hexapeptide -3 of 0.02%-0.035%, the Matrixyl -3 of 0.001%-0.01%, 0.025%-0.035% Palmityl tetrapeptide -7, the palmitoyl tripeptide 3 of 0.025%-0.035%, the dipeptides -2 of 0.08%-0.12%, 0.1%-0.2% acetyl Tetrapeptide -5,4%-6% glycerol, 0.2%-0.4% Sodium Hyaluronate, 0.3%-0.5%1,2- hexylene glycol, surplus are pure water. But above-mentioned prior art formula is complicated, and preparation process is cumbersome, with high costs, and it is not satisfactory to repair skin effect.

In conclusion researching and developing a kind of polypeptide active compound, sensitive skin of releiving is repaired, skin function is improved, is changing Cosmetic field has broad application prospects and huge market value.

Summary of the invention

In view of the deficiencies of the prior art with the demand in market, the present invention provides a kind of composition for repairing sensitive skin and It is applied, and by multiplex screening active component, reasonably combined polypeptide ratio mentions so that composition has comprehensive reparation skin The effect of rising skin quality, has broad application prospects and huge market value.

To achieve the above object, in a first aspect, the present invention provides a kind of composition for repairing sensitive skin, the composition - 8 solution of palmityl tripeptides and 0.5- of ultimate attainment reparation peptide including 0.5-10.0%, 0.5-10.0% by weight percent 10.0% deacetylated carboxymethyl chitosan solution；The ultimate attainment reparation peptide include palmityl tetrapeptide -7, tripeptides -1, hexapeptide -9, Matrixyl -4, palmityl tripeptides -1 and palmityl tripeptides -5.

In the present invention, inventor has effects that the active component of reparation by screening layer by layer, after multiple composite test, The excellent ratio of this composition is grasped, each component is mutually promoted in the ultimate attainment reparation peptide, cooperates with palmityl tripeptides -8 With deacetylated carboxymethyl chitosan, there is comprehensive reparation skin, promote skin quality, promote regeneration compact, smooth static line, Long-acting anti-ageing effect.

Preferably, the composition by mass fraction includes the ultimate attainment reparation peptide of 0.5-10.0%, such as can be 0.5%, 1.0%, 2.0%, 3.0%, 4.0%, 5.0%, 6.0%, 7.0%, 8.0%, 9.0% or 10.0%.

Preferably, the composition further includes -8 solution of palmityl tripeptides of 0.5-10.0% by weight percent, such as It can be 0.5%, 1.0%, 2.0%, 3.0%, 4.0%, 5.0%, 6.0%, 7.0%, 8.0%, 9.0% or 10.0%.

In the present invention, the palmityl tripeptides -8 are a kind of for alleviating the tripeptides of sensitive skin Neurogenic inflammatory, effectively Prevent and mitigate the inflammation and symptom caused by chemical stimulation.

Preferably, the composition further includes that the deacetylated carboxymethyl chitosan of 0.5-10.0% is molten by weight percent Liquid, for example, can be 0.5%, 1.0%, 2.0%, 3.0%, 4.0%, 5.0%, 6.0%, 7.0%, 8.0%, 9.0% or 10.0%.

Preferably, it is described it is ultimate attainment repair peptide in each component mass percent be 0.01-0.03% palmityl tetrapeptide -7, The tripeptides -1 of 0.03-0.06%, the hexapeptide -9 of 0.03-0.05%, 0.03-0.06% Matrixyl -4,0.02-0.04% Palmityl tripeptides -1 and 0.01-0.03% palmityl tripeptides -5.

Preferably, it is described it is ultimate attainment repair peptide weight percent further include 19.8-49.8% water and 50-80% it is sweet Oil.

Preferably, -8 solution weight percent of palmityl tripeptides include 0.03-0.04% palmityl tripeptides -8, The butanediol of 50-80% and the water of 20-50%, the sum of percentage are no more than 100%.

Preferably, the carboxymethylchitosan solution weight percent includes that the deacetylated shell of 88% carboxymethyl is more The sugared water with 12%.

In the present invention, the deacetylated carboxymethyl chitosan, which has to have itch caused by histamine, tingling sensation, significantly to disappear It removes, therapeutic effect；There are apparent alleviation, repair to red and swollen, bleb.

In the present invention, three kinds of active materials: ultimate attainment reparation peptide, palmityl tripeptides -8 and deacetylated carboxymethyl chitosan are mutual Collocation, it is synergistic, by being added in cosmetics, have effects that obviously to repair and releive to sensibility skin, specially Door is directed to sensitive skin Important source material improves the metabolism of skin histology, repairs skin and reach best physiology shape by adjusting skin physiology function State.

Second aspect, the present invention provide the application that a kind of composition as described in relation to the first aspect is used to prepare cosmetics.

The present invention uses polypeptide composition, more coincide the psychological need of skin and skin itself has and more increases Xiang Rongdu, the effect of capable of preferably playing active matter, have good repairing effect for the sensibility skin of easy allergy, can relax Caused radical response, enhances the defensive barrier ability of skin when slow skin is by environmental stimuli.

The third aspect, the present invention provide a kind of cosmetics, include composition described in first aspect in the cosmetics.

Preferably, the cosmetics include in skin cream, lotion, face cream, toner, facial mask or essence any one or At least two combination, preferably essence.

Preferably, the essence further includes moisturizer and pH condition agent.

Fourth aspect, the present invention provide a kind of preparation method of essence, include the following steps:

(1) Sodium Hyaluronate and glycerol are added to the water, heating stirring makes to be uniformly mixed；

(2) product of step (1) is cooled down, is proportionally added into ultimate attainment reparation peptide, -8 solution of palmityl tripeptides, deacetylated carboxylic Methyl chitin solution, stirs evenly；

(3) pH value of the product of step (2) is adjusted to by 5-6 using pH adjusting agent, obtains the essence.

Preferably, the temperature of step (1) described heating be 60-75 DEG C, such as can be 60 DEG C, 63 DEG C, 65 DEG C, 67 DEG C, 69 DEG C, 70 DEG C, 73 DEG C or 75 DEG C.

Preferably, the mass percent of step (1) described Sodium Hyaluronate is 0.1-0.5%, such as can be 0.1%, 0.2%, 0.3%, 0.4% or 0.5%, the mass percent of glycerol is 6-10%, for example, can be 6%, 7%, 8%, 9% or 10%.

Preferably, the temperature range of step (2) described cooling is 20-30 DEG C, such as can be 20 DEG C, 23 DEG C, 25 DEG C, 27 DEG C, 29 DEG C or 30 DEG C.

Preferably, step (2) ratio are as follows: the palmityl tripeptides-of the ultimate attainment reparation peptide of 0.5-8.0%, 0.5-8.0% The deacetylated carboxymethyl chitosan solution of 8 solution, 0.5-8.0%.

As optimal technical scheme, a method of essence is prepared, is specifically comprised the following steps:

(1) glycerol of the Sodium Hyaluronate of 0.1-0.5% and 6-10% is added to the water, is heated to 60-75 DEG C of stirring Make to be uniformly mixed；

(2) product of step (1) is cooled to 20-30 DEG C, weight percent be added 0.5-8% ultimate attainment reparation peptide, The deacetylated carboxymethyl chitosan solution of -8 solution of palmityl tripeptides of 0.5-8%, 0.5-8%, stirs evenly；

(3) pH value of the product of step (2) is adjusted to by 5-6 using pH adjusting agent, obtains the essence.

Compared with prior art, the present invention has the advantage that

Composition provided by the invention is based on polypeptide active component and is meeting skin histology specifically for sensitive skin On the basis of compatibility and cutaneous safety, by adjusting skin physiology function, improves the metabolism of skin histology, repair flesh Skin reaches best physiological status, has effects that obviously to repair and releive for sensibility skin, and lactic acid stimulates change rate Up to 31.5%；The psychological need of more identical skin has the mutually degree of melting more increased with skin itself, can preferably play work Property object the effect of, for easy allergy sensibility skin have good repairing effect, when can soothe the skin by environmental stimuli Caused radical response enhances the defensive barrier ability of skin.

Specific embodiment

Further to illustrate technological means and its effect adopted by the present invention, below in conjunction with preferred implementation of the invention Example to further illustrate the technical scheme of the present invention, but the present invention is not limited in scope of embodiments.

The preparation of 1 essence I of embodiment

(1) glycerol of 0.3% Sodium Hyaluronate and 8% is added to the water, being heated to 70 DEG C of stirrings makes to be uniformly mixed；

(2) product of step (1) is cooled to 25 DEG C, 2% ultimate attainment reparation peptide, 2% palm fibre is added in weight percent - 8 solution of palmitic acid acyl tripeptides, 2% deacetylated carboxymethyl chitosan solution, stir evenly；

(3) pH value of the product of step (2) is adjusted to 5.5 using pH adjusting agent, obtains the essence.

The preparation of 2 essence II of embodiment

(1) glycerol of 0.1% Sodium Hyaluronate and 6% is added to the water, being heated to 60 DEG C of stirrings makes to be uniformly mixed；

(2) product of step (1) is cooled to 20 DEG C, the ultimate attainment reparation peptide of weight percent addition 0.5%, 0.5% - 8 solution of palmityl tripeptides, 0.5% deacetylated carboxymethyl chitosan solution, stir evenly；

(3) pH value of the product of step (2) is adjusted to 5 using pH adjusting agent, obtains the essence.

The preparation of 3 essence III of embodiment

(1) glycerol of 0.5% Sodium Hyaluronate and 10% is added to the water, being heated to 75 DEG C of stirrings keeps mixing equal It is even；

(2) product of step (1) is cooled to 30 DEG C, weight percent be added 10% ultimate attainment reparation peptide, 10% - 8 solution of palmityl tripeptides, 10% deacetylated carboxymethyl chitosan solution, stir evenly；

(3) pH value of the product of step (2) is adjusted to 6 using pH adjusting agent, obtains the essence.

The preparation of 4 essence IV of embodiment

(1) glycerol of 0.2% Sodium Hyaluronate and 9% is added to the water, being heated to 65 DEG C of stirrings makes to be uniformly mixed；

(2) product of step (1) is cooled to 28 DEG C, 8% ultimate attainment reparation peptide, 8% -8 solution of palmityl tripeptides, 8% deacetylated carboxymethyl chitosan solution, stirs evenly；

(3) pH value of the product of step (2) is adjusted to 5.8 using pH adjusting agent, obtains the essence.

The preparation of 5 essence V of embodiment

(1) glycerol of 0.4% Sodium Hyaluronate and 7% is added to the water, being heated to 72 DEG C of stirrings makes to be uniformly mixed；

(2) product of step (1) is cooled to 22 DEG C, 5% ultimate attainment reparation peptide, 5% -8 solution of palmityl tripeptides, 5% deacetylated carboxymethyl chitosan solution, stirs evenly；

(3) pH value of the product of step (2) is adjusted to 5.2 using pH adjusting agent, obtains the essence.

The preparation of 6 lotion of embodiment

Lotion comprising repairing the composition of sensitive skin, formula such as the following table 1:

Table 1

Preparation process is as follows:

1, by A group material Hybrid Heating to 80 DEG C, dissolution completely, keeps the temperature 5-8min；

2, by B group material Hybrid Heating to 80 DEG C, dissolution completely, keeps the temperature 5-8min；

3, room temperature mixing C group material, stirring and dissolving is complete, spare；

4, A, B group material of good heat insulation are mixed, then homogeneous 4-5min is added C group material and adjusts PH, drops after mixing evenly Temperature；

5, it is separately added into D group material after cooling to 38-40 DEG C, after mixing evenly, is cooled to room temperature discharging.

Comparative example 1

Compared with Example 1, in addition to not adding ultimate attainment reparation peptide, with outside water polishing, other conditions are same as Example 1.

Comparative example 2

Compared with Example 1, in addition to not adding -8 solution of palmityl tripeptides, with outside water polishing, other conditions and embodiment 1 It is identical.

Comparative example 3

Compared with Example 1, in addition to not adding deacetylated carboxymethyl chitosan solution, with outside water polishing, other conditions with Embodiment 1 is identical.

Comparative example 4

Compared with Example 1, other than the ultimate attainment additive amount for repairing peptide is changed to 12%, other conditions are same as Example 1.

Comparative example 5

Compared with Example 1, other than the additive amount of -8 solution of palmityl tripeptides is changed to 12%, other conditions and embodiment 1 is identical.

Comparative example 6

Compared with Example 1, other than the additive amount of deacetylated carboxymethyl chitosan solution is changed to 12%, other conditions with Embodiment 1 is identical.

Experiment detection

Anti-irritant test

Sensitive skin crowd (tingling sensation adds up >=3 points of persons) 120 is chosen, the age, men and women was fifty-fifty at 20-45 years old.At random It is divided into 12 groups, every group of 5 males, 5 women；The recipient site of subject before testing 15 days cannot use any cosmetics, Topical drug or health care product for oral administration, before test, it is desirable that it is 22 that subject, which cleans facial area and enters temperature in 2 hours after cleaning, ± 1 DEG C, sit quietly 30min in the constant temperature and humidity room that humidity is 50 ± 5%, and keep relaxation state；

Experiment carries out half of face test by random table, and the essence of embodiment 1, another side face are smeared by the side face of subject One of essence, the essence of comparative example 1-6 and the lotion of embodiment 6 of embodiment 2-5 is smeared in portion, selects subject's nasolabial groove Position is tested, by 10% lactic acid solution of 50 μ L drop on the single layer filter paper that diameter is 0.8cm, respectively 3min, 4min and 5min inquire subject's tingling sensation, scored by 4 point-scores (0 point is no tingling sensation, and 1 point is slight shouting pain, 2 points For moderate shouting pain, 3 points are severe shouting pain), the scoring for recording subject stimulates scoring initial value (D0), experiment as the side lactic acid It carries out 15 days altogether, subject needs to use product each 1 time sooner or later daily as requested, and avoids cross contamination, and subject need to be the (D15) is paid a return visit within 15 days；Consistent lighting condition, the tilt angle of bed and placement position should be kept a kind of when test, it is same The test of subject is completed by the same survey crew, calculates lactic acid stimulus result change rate %, the results are shown in Table 2；

Table 2

Sample	Lactic acid stimulation scoring change rate
		Embodiment 1	-31.5
Embodiment 2	-28.3
		Embodiment 3	-28.9
Embodiment 4	-28.5
		Embodiment 5	-30.0
Embodiment 6	-28.8
		Comparative example 1	-10.2
Comparative example 2	-11.3
		Comparative example 3	-12.8
Comparative example 4	-18.3
		Comparative example 5	-19.5
Comparative example 6	-19.7

As shown in Table 2, the essence and embodiment 6 that embodiment 1-5 is prepared according to technical solution provided by the invention are made The lotion obtained is brilliant to the repairing effect of sensitive skin, and lactic acid stimulates change rate to be greater than 28%, wherein the effect of embodiment 1 is most It is good, reach 31.5%, and comparative example 1-3 lacks any component of composition, component additive amount over range in comparative example 4-6, The effect for repairing skin of releiving is had a greatly reduced quality, it was demonstrated that and composition of the invention is indispensable, cooperates, and improves skin function, Skin of releiving is repaired comprehensively.

Sensitive skin cures test

Volunteer's survey is carried out to lotion made from essence obtained by embodiment 1-5 and comparative example 1-6 and embodiment 6 Examination, to evaluate its validity.Each experimental group arranges volunteer 120, is randomly divided into 12 groups, the age 20-60 years old, be sensitive flesh Skin；Application method: taking appropriate cosmetics to apply uniformly in face, then gently massages 3-5 minutes, twice a day, continuously tries out 12 Week, evaluation method: weekly observe 1 time, when every group 60% or more of people's sensitivity skin phenomenon cured be then recorded as effectively, And recording is which week is i.e. effective, specific test result such as table 3；

Table 3

As shown in Table 3, the essence and embodiment 6 that embodiment 1-5 is prepared according to technical solution provided by the invention are made The lotion obtained has effects that significantly to repair to sensitive skin crowd cures, and wherein the essence reparation of embodiment 1 cures speed most Fastly, skin sensitivity phenomenon is cured in third week, and comparative example 1-3 lacks any component, three kinds of component additions in comparative example 4-6 Over range is measured, the reparation curative effect of essence is all substantially reduced, and the time extends, and shows composition each component association provided by the invention Same synergy, it is indispensable, it mutually promotes, it is common to repair sensitive skin of releiving.

Meeting in conclusion composition provided by the invention is based on polypeptide active component specifically for sensitive skin On the basis of skin histology compatibility and cutaneous safety, by adjusting skin physiology function, improve the new old generation of skin histology It thanks, repairs skin and reach best physiological status, have effects that obviously to repair and releive for sensibility skin, have wide Wealthy application prospect and huge market value.

The Applicant declares that the present invention is explained by the above embodiments method detailed of the invention, but the present invention not office Be limited to above-mentioned method detailed, that is, do not mean that the invention must rely on the above detailed methods to implement.Technical field Technical staff it will be clearly understood that any improvement in the present invention, equivalence replacement and auxiliary element to each raw material of product of the present invention Addition, selection of concrete mode etc., all of which fall within the scope of protection and disclosure of the present invention.

Claims (10)

1. a kind of composition for repairing sensitive skin, which is characterized in that the composition includes 0.5- by weight percent The deacetylated carboxymethyl shell of 10.0% ultimate attainment reparation peptide, -8 solution of palmityl tripeptides of 0.5-10.0% and 0.5-10.0% is more Sugar juice；

Wherein, the ultimate attainment reparation peptide includes palmityl tetrapeptide -7, tripeptides -1, hexapeptide -9, Matrixyl -4, palmityl three Peptide -1 and palmityl tripeptides -5.

2. composition according to claim 1, which is characterized in that the composition includes 0.5- by weight percent 8.0% ultimate attainment reparation peptide, -8 solution of palmityl tripeptides of 0.5-8.0% and the deacetylated carboxymethyl chitosan of 0.5-8.0% Solution.

3. composition according to claim 1 or 2, which is characterized in that the composition includes 0.5- by weight percent 5.0% ultimate attainment reparation peptide, -8 solution of palmityl tripeptides of 0.5-5.0% and the deacetylated carboxymethyl chitosan of 0.5-5.0% Solution；

Preferably, it is described it is ultimate attainment repair peptide in each component mass percent be 0.01-0.03% palmityl tetrapeptide -7, The tripeptides -1 of 0.03-0.06%, the hexapeptide -9 of 0.03-0.05%, 0.03-0.06% Matrixyl -4,0.02-0.04% Palmityl tripeptides -1 and 0.01-0.03% palmityl tripeptides -5；

Preferably, the ultimate attainment reparation peptide weight percent further includes the water of 19.8-49.8% and the glycerol of 50-80%；

Preferably, -8 solution weight percent of palmityl tripeptides includes the palmityl tripeptides -8 of 0.03-0.04%, 50- 80% butanediol and the water of 20-50%, the sum of percentage are no more than 100%；

Preferably, the carboxymethylchitosan solution weight percent include 88% carboxymethylchitosan and 12% water.

4. the application that a kind of composition as described in any one of claim 1-3 is used to prepare cosmetics.

5. a kind of cosmetics, which is characterized in that include composition of any of claims 1-3 in the cosmetics.

6. cosmetics according to claim 5, which is characterized in that the cosmetics include skin cream, face cream, lotion, feel well In skin water, facial mask or essence any one or at least two combination, preferably essence.

7. cosmetics according to claim 6, which is characterized in that the essence further includes moisturizer and pH condition agent.

8. a kind of preparation method of essence, which comprises the steps of:

(1) Sodium Hyaluronate and glycerol are added to the water, heating stirring makes to be uniformly mixed；

(2) product of step (1) is cooled down, is proportionally added into ultimate attainment reparation peptide, -8 solution of palmityl tripeptides, deacetylated carboxymethyl Chitin solution, stirs evenly；

(3) pH value of the product of step (2) is adjusted to by 5-6 using pH adjusting agent, obtains the essence.

9. according to the method described in claim 8, it is characterized in that, the temperature of step (1) described heating is 60-75 DEG C；

Preferably, the mass percent of step (1) described Sodium Hyaluronate is 0.1-0.5%, and the mass percent of glycerol is 6- 10%；

Preferably, the temperature range of step (2) described cooling is 20-30 DEG C；

Preferably, step (2) ratio are as follows: the ultimate attainment reparation peptide of 0.5-8.0%, the palmityl tripeptides -8 of 0.5-8.0% are molten The deacetylated carboxymethyl chitosan solution of liquid, 0.5-8.0%.

10. method according to claim 8 or claim 9, which is characterized in that specifically comprise the following steps:

(1) glycerol of the Sodium Hyaluronate of 0.1-0.5% and 6-10% is added to the water, being heated to 60-75 DEG C of stirring makes to mix It closes uniform；

(2) product of step (1) is cooled to 20-30 DEG C, the palmityl tripeptides -8 of the ultimate attainment reparation peptide of 0.5-8%, 0.5-8% The deacetylated carboxymethyl chitosan solution of solution, 0.5-8%, stirs evenly；

(3) pH value of the product of step (2) is adjusted to by 5-6 using pH adjusting agent, obtains the essence.