CN108967666A - A kind of antiseptic feed additive and application thereof - Google Patents
A kind of antiseptic feed additive and application thereof Download PDFInfo
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Abstract
The present invention discloses a kind of antiseptic feed additive and application thereof, the antiseptic feed additive includes lauric monoglyceride, the antiseptic feed additive is used to substitute the antibiotics additive in animal feed, application method are as follows: the antiseptic feed additive is directly added into feed and feeds livestock and poultry or aquatic livestock；Or, the antiseptic feed additive is prepared into pre-mixing agent, premix or concentrate feed, then the pre-mixing agent, premix or concentrate feed are added in feed and feed livestock and poultry or aquatic livestock.Antiseptic feed additive provided by the invention includes lauric monoglyceride, with high security, the advantages of having no drug resistance, feeding antibiotic can effectively be substituted, meet healthy aquaculture developing direction, it can be used for preventing and treating the disease as caused by Escherichia coli, Sharpe door bacterium, staphylococcus aureus and streptococcus pneumonia, by inhibiting the breeding of animal intestinal tract harmful microbe, and then promote the incidence of growth of animal, disease of improving food conversion ratio, reduce.
Description
Technical field
The present invention relates to livestock and poultry cultivation technical field, in particular to a kind of antiseptic feed additive and application thereof.
Background technique
Antibiotic has more than 60 years history for pig production, and in livestock and poultry cultivation production, antibiotic is mainly used for pre-
Anti- disease and promotion growth.The whole world be about more than 50% antibiotic total amount be used for edible animal production, wherein 90% use
In growth promoting function and improve food conversion ratio.In neoteric and modern livestock and poultry breeding industry, antibiosis rope unquestionably plays important
Effect, brings significant economic benefit to livestock and poultry breeding industry.But since antibiotic is producing unreasonable in practice and abuse etc.
Phenomenon is used for a long time in addition and causes the drug resistance of bacterial antibiotic, has scholar's scream, the mankind will be available into no medicine
" rear antibiotic epoch " or " drug resistance epoch ".
In recent years, the step of China's feeding antibiotic disabling is gradually accelerated, and available antibiotic is fewer and fewer in feed, grinds
It is extremely urgent to send out Substitutes For Antibiotic.Ideal Substitutes For Antibiotic should have the following characteristics that 1. substance itself or its metabolism produce
Object has no toxic side effect to animal；2. small without acting on or acting on to environment；3. being not easy or not inducing drug-fast bacteria generation, also it is not easy to induce
The generation of crossing drug resistant bacterium；4. killing or inhibiting the growth and breeding of pathogenic microorganism；5. not influencing feed palatability.It is current feeding
Substitutes For Antibiotic is constantly weeded out the old and bring forth the new, and existing Related product includes antibacterial peptide, plants essential oil, acidulant etc., and there are all
Such as production technology is not perfect, product quality is difficult to ensure, asks nutriment in feed processing conditional instability, destruction feed
Topic.
Summary of the invention
The main object of the present invention is to propose a kind of antiseptic feed additive and application thereof, it is desirable to provide a kind of antibacterial effect
Good antiseptic feed additive.
To achieve the above object, the present invention proposes that a kind of antiseptic feed additive, the antiseptic feed additive include the moon
Cinnamic acid monoglyceride.
The present invention also proposes purposes of the antiseptic feed additive as described above in animal feed, and the antiseptic feed adds
Add agent for substituting the antibiotics additive in animal feed, the application method of the antiseptic feed additive are as follows:
The antiseptic feed additive is directly added into perfect compound feed and feeds livestock and poultry or aquatic livestock；Or,
The antiseptic feed additive is directly added into premix or concentrate feed, then by the premix or described dense
Contracting material feeds livestock and poultry or aquatic livestock after perfect compound feed is made with other feedstuffs；Or,
The antiseptic feed additive and carrier are prepared by mixing into pre-mixing agent, then by the pre-mixing agent and other feeds
Raw material feeds livestock and poultry or aquatic livestock after perfect compound feed is made；Or,
After the antiseptic feed additive and carrier are mixed and made into pre-mixing agent, premix or dense is added in the pre-mixing agent
In contracting material, then the premix or the concentrate feed and other feedstuffs are made after perfect compound feed feed livestock and poultry or
Aquatic livestock.
Preferably, the additive amount of the antiseptic feed additive is the 0.01~1.0% of the animal feed gross mass.
Antiseptic feed additive provided by the invention includes lauric monoglyceride, with high security, is had no drug resistance
Advantage can effectively substitute feeding antibiotic, meet healthy aquaculture developing direction, can be used for preventing and treating by Escherichia coli, Sharpe door
Disease caused by bacterium, staphylococcus aureus and streptococcus pneumonia, by inhibiting the breeding of animal intestinal tract harmful microbe, into
And promote the incidence of growth of animal, disease of improving food conversion ratio, reduce.
Specific embodiment
It in order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below will be in the embodiment of the present invention
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, according to normal conditions or manufacturer builds
The condition of view carries out.Reagents or instruments used without specified manufacturer is the conventional production that can be obtained by commercially available purchase
Product.
The present invention proposes that a kind of antiseptic feed additive, the antiseptic feed additive include lauric monoglyceride.With
Lauric monoglyceride is as antiseptic feed additive, after having the advantage that (1) lauric monoglyceride is taken in by animal,
It is decomposed into lauric acid and glycerol under the action of lipase in vivo, both for metabolite normal in animal body, to the mankind
It is without any side effects with animal body；(2) compared with antibiotics feed addictive, lauric monoglyceride has noresidue, no
The advantage of drug resistance can be generated；(3) the non-corrosive effect of lauric monoglyceride, chemical property are stablized, can to avoid to feed,
The destruction of the nutriments such as vitamin, minerals especially in premix avoids the acid corrosion to feed-processing equipment from damaging；
(4) lauric monoglyceride is added in feed, will not influence compared with antibiotic (bitter taste) without bad aroma and flavor
The palatability of feed.Therefore using lauric monoglyceride as ideal feeding antibiotic substitute, with high security, stablize
Property it is good, have no drug resistance, the advantages that palatability is strong, by inhibiting the breeding of animal intestinal tract harmful microbe, and then promote animal raw
Incidence that is long, improving feed efficiency, reduce disease, can effective substitute antibiotics, meet the development side of healthy aquaculture
To.
The antiseptic feed additive can be only made of the lauric monoglyceride, can also be by the lauric acid list
Glyceride forms the antiseptic feed additive after compounding with carrier appropriate, the carrier can select defatted rice bran, dioxy
The carrier of the field of fodder routine such as SiClx or zeolite powder will include below lauric monoglyceride with the antiseptic feed additive
It is illustrated with for defatted rice bran.The antiseptic feed additive further includes defatted rice bran, the lauric monoglyceride with
The mass ratio of the defatted rice bran is 1:(0.5~3), preferably 1:1, in this way, the lauric monoglyceride is taken off with described
The antiseptic feed additive is made after the mixing of rouge rice bran, it can be to avoid the lauric monoglyceride due to being directly exposed to ring
It contacts in border or with the other compositions in feed when in use and causes to inactivate or be denaturalized.
Purposes of the antiseptic feed additive in animal feed is that the antiseptic feed additive is dynamic for substituting
Antibiotics additive in object feed, the application method of the antiseptic feed additive are as follows: by the antiseptic feed additive
It is directly added into perfect compound feed and feeds livestock and poultry or aquatic livestock；Or, the antiseptic feed additive is directly added into premix
In material or concentrate feed, fed after perfect compound feed then is made with other feedstuffs in the premix or the concentrate feed
Livestock and poultry or aquatic livestock；Or, the antiseptic feed additive and carrier are prepared by mixing into pre-mixing agent, then by the pre-mixing agent
Livestock and poultry or aquatic livestock are fed after perfect compound feed is made with other feedstuffs；Or, by the antiseptic feed additive with
After carrier is mixed and made into pre-mixing agent, the pre-mixing agent is added in premix or concentrate feed, then by the premix or described
Concentrate feed and other feedstuffs feed livestock and poultry or aquatic livestock after perfect compound feed is made.The livestock and poultry or aquatic livestock packet
Weanling pig, broiler chicken, laying hen or crucian etc. are included but are not limited to, the difference of the animal species fed when according to practical application,
Different perfect compound feed or other feedstuffs for preparing perfect compound feed can be accordingly selected, for example, working as institute
When the animal of feeding is piglet, then the perfect compound feed or other feedstuffs suitable for piglet should be selected, when what is fed
When animal is freshwater fish, then the perfect compound feed or other feedstuffs suitable for freshwater fish should be selected, needs to illustrate
, the perfect compound feed or the feedstuff for preparing perfect compound feed are the state of the art, herein
It does not repeat them here.
The application method of the antiseptic feed additive other than being prepared into pre-mixing agent, premix or the form of concentrate feed,
Feeding animals in animal feed can also be added directly into, such as the antiseptic feed additive and animal feed is basic
The effect of daily ration is used for feeding animals after evenly mixing, can realize antibacterial and internal by animal intake.
It is understood that the antiseptic feed additive to be whether made to the shape of pre-mixing agent, premix or concentrate feed
Formula, or the antiseptic feed additive is added directly into the basal diet of animal feed, the antiseptic feed additive
Administration mode be to be administered by feed, therefore, the antiseptic feed additive in actual use, with the antiseptic feed
The additive amount of additive accounts for subject to the 0.01~1.0% of animal feed gross mass, and in this dosage range, the antiseptic feed adds
Add agent to can be used for preventing and treating the disease as caused by Escherichia coli, Sharpe door bacterium, staphylococcus aureus and streptococcus pneumonia, passes through
Inhibit the breeding of animal intestinal tract harmful microbe, and then promotes growth of animal, improve food conversion ratio, reduce disease incident
Effect.
In conclusion antiseptic feed additive provided by the invention includes lauric monoglyceride, with high security, nothing
The advantages of drug resistance, can effectively substitute feeding antibiotic, meet healthy aquaculture developing direction, can be used for preventing and treating by large intestine bar
Disease caused by bacterium, Sharpe door bacterium, staphylococcus aureus and streptococcus pneumonia, by inhibiting animal intestinal tract harmful microorganism
Breeding, and then promote growth of animal, disease of improving food conversion ratio, reduce incidence.
Technical solution of the present invention is described in further detail below in conjunction with specific embodiment, it should be understood that following real
It applies example to be only used to explain the present invention, be not intended to limit the present invention.
Minimal inhibitory concentration of 1 lauric monoglyceride of Application Example to gram- bacteria
Using enzyme mark turbidimetry for Determination lauric monoglyceride to Escherichia coli, salmonella, staphylococcus aureus and
The minimal inhibitory concentration of streptococcus pneumonia is diluted lauric monoglyceride with 2 times of ratios in sterile 96 porocyte plates step by step
It is mixed at various concentration and sterile meat soup, the bacteria suspension of same volume is then added in each hole solution, each processing repeats 2
It is secondary.OD is measured using microplate reader600After being worth (absorbance value at 600nm), 37 DEG C of constant temperature, constant humidity culture for 24 hours, measure this again
Each hole OD of cell plates600Value, calculates each hole OD600Difference.It can make to cultivate forward and backward OD600Difference △ OD600≤ 0.05 antibacterial agent is minimum
Concentration can be determined as minimum inhibitory concentration (MIC) in conjunction with defecator is visually observed, as a result as shown in table 1 below.
1 lauric monoglyceride of table is to Escherichia coli, salmonella, staphylococcus aureus and streptococcus pneumonia
Minimal inhibitory concentration (μ g/ml)
By the result in table 1 it is found that lauric monoglyceride to Escherichia coli, salmonella, staphylococcus aureus and
Streptococcus pneumonia is by significant fungistatic effect, and lauric monoglyceride is blue better than leather to the inhibitory effect of gram-positive bacteria
Family name's negative bacterium, it is best to the inhibitory effect of streptococcus pneumonia.
2 antiseptic feed additive of Application Example is for feeding weanling pig
(1) lauric monoglyceride and defatted rice bran are sufficiently mixed according to the mass ratio of 1:1, are prepared into antiseptic feed and add
Add agent.
(2) weight and the consistent weanling pig of gender that 96 21 ages in days disposably wean are chosen, is randomly divided into 4 groups, packet
Include control group, test I group, test II group and test III group, 3 repetitions (column) of every component, 8, every column.The basis of each group feeding
Daily ration is consistent, the difference is that, the feed in I, II, III group of test is added with respectively accounts for total feed quality 0.1%, 0.5%
With 1.0% antiseptic feed additive (step (1) be made, in practical feed respectively containing lauric monoglyceride 0.05%,
0.25% and 0.5%), the quinocetone of 50mg/kg is added in the feed in control group.Feeding 21 days, statistics weanling pig are raw
Micro organism quantity in long performance and excrement.
The growth performance of weanling pig includes average daily gain, average daily gain, feed-weight ratio and diarrhea rate, statistical result
(in table 2, colleague's shoulder mark difference lowercase letter indication difference is significant (P < 0.05)) as shown in table 2 below.
The growth performance of weanling pig in 2 Application Example 2 of table
Quinocetone (Quinocetone) is the newly developed livestock and poultry of Lanzhou Livestock and Animal Drug Inst., Chinese Academy of Agricultural Science
Antibacterial, antidiarrheal, growth promotion new drug are a kind of novel chiral synthons that China initiates in the world.Faint yellow or yellow greenish powder, does not dissolve in
Water is slightly soluble in part organic solvent, light sensitive, is easier to that photochemical reaction occurs.Quinocetone category quinoxaline class drug, can promote
It grows and improves food conversion ratio, have inhibiting effect to a variety of pathogenic entero becterias (especially Gram-negative bacteria), can obviously drop
Low livestock and poultry diarrhea incidence.
By the result in table 2 it is found that using provided by the present invention anti-using lauric monoglyceride as active constituent
Bacterium feed addictive, compared with the control group of addition quinocetone, weanling pig average daily gain is respectively increased in I, II, III group of test
6.70%, 8.51% (P < 0.05) and 6.44% is reduced feed-weight ratio 5.03%, 5.03% and 5.66% (P < 0.05), significantly
It reduces Incidence of Diarrhea 29.83%, 35.83% and 40.52% (P < 0.05), illustrates antiseptic feed addition provided by the invention
Agent is more significant to the application effect of weanling pig.
In weanling pig excrement the statistical result of micro organism quantity it is as shown in table 3 below (in table 3, shoulder mark difference small letter of going together
Letter indicates significant difference (P < 0.05)).
In 3 Application Example 2 of table in weanling pig excrement microorganism quantity (1g (CFU/g))
| Project | Control group | Test I group | Test II group | Test III group |
| Total plate count | 9.44±0.06a | 9.04±0.05ab | 8.92±0.06ab | 8.84±0.07b |
| Escherichia coli | 8.75±0.04 | 8.25±0.06 | 8.17±0.04 | 8.02±0.03 |
By the result in table 3 it is found that compared with the control group, test total plate count in I, II, III group of excrement reduces respectively
4.23%, 5.51% and 6.36% (P < 0.05), Escherichia coli quantity reduce 5.71%, 6.63% and 8.34% (P respectively
< 0.05), illustrate, feeds weanling pig using antiseptic feed additive provided by the invention, piglet can be promoted to grow, reduce
The quantity of enteron aisle Escherichia coli, reduces intestines problem, has the function of substitute antibiotics.
3 antiseptic feed additive of Application Example is used for feeding dorking
(1) lauric monoglyceride and defatted rice bran are sufficiently mixed according to the mass ratio of 1:1, are prepared into antiseptic feed and add
Add agent.
(2) the almost the same Cobb Broiler chicks (half male and half female) of 160 1 age in days weight are chosen, are randomly divided into 2 groups, including
Control group and test group, 8 repetitions (cage) of every component, 10, every cage.Test group is consistent with the basal diet of control group fed, no
It is with place, added with antiseptic feed additive (step (1) system for accounting for total feed quality 0.04% in the feed of test group
, lauric monoglyceride 0.02% is contained in practical feed), 4mg/kg flavomycoin is added in the feed of control group.Feeding
42 days, count the quantity of microorganism in meat chicken growth performance and excrement, statistical result (4 He of table as shown in the following table 4 and table 5 respectively
In table 5, colleague's shoulder mark difference lowercase letter indication difference is significant (P < 0.05)).
The growth performance of broiler chicken in 4 Application Example 3 of table
| Project | Control group | Test group |
| Average daily gain (g/ is only) | 51.3±7.12b | 58.7±5.33a |
| Average daily gain (g/ is only) | 92.83±11.23b | 99.83±10.69a |
| Feed-weight ratio | 1.81±0.08a | 1.70±0.07b |
The quantity (1g (CFU/g)) of broiler chicken fecal microorganism in 5 Application Example 3 of table
| Project | Control group | Test I group |
| Escherichia coli | 7.84±0.08 | 7.36±0.05 |
| Lactic acid bacteria | 7.21±0.04 | 7.78±0.06 |
Flavomycoin is phosphorylated polysaccharide class antibiotic, and Antibacterial mechanism is the structural material peptide by interfering cell wall
The biosynthesis of glycan is to inhibit the breeding of bacterium.The growth promotion principle of flavomycoin may is that it can improve Dietary Energy
With the digestion of protein；Intestinal wall can be made thinning to improve the absorption of nutriment；The balance of intestinal flora can effectively be maintained
With the stabilization of ruminal pH value.Bacterium is not likely to produce drug resistance to flavomycoin, and flavomycoin, which is also not easy to generate with other antibiotic, to intersect
Drug resistance, flavomycoin antimicrobial spectrum is relatively narrow, mainly effective to gram-positive bacteria, and to the Gram-positive of other antibiotics resistances
Bacterium is also effective, but acts on Gram-negative bacteria very weak.
By the result in table 4 and table 5 it is found that using antiseptic feed additive feeding dorking of the present invention, with addition
The control group of flavomycoin is compared, and test group significantly improves broiler chicken average daily gain 14.42% (P < 0.05), significantly reduces material
Again than 6.07% (P < 0.05)；Compared with the control group of addition flavomycoin, adding antiseptic feed additive provided by the invention can
To reduce Escherichia coli quantity in broiler chicken excrement, increase lactic acid bacterium number.The above results explanation, using antibacterial provided by the invention
Feed addictive feeding dorking can promote growth of meat chicken, reduce the quantity of enteron aisle Escherichia coli, increase lactic acid bacterium number, tool
There are substitute antibiotics.
4 antiseptic feed additive of Application Example is for feeding laying hen
(1) lauric monoglyceride and defatted rice bran are sufficiently mixed according to the mass ratio of 1:1, are prepared into antiseptic feed and add
Add agent.
(2) 1600 blue brown laying hens in 270 ages in days sea are chosen, 2 groups, including control group and test group, every group of 4 weights are divided into
It is multiple, each repetition 200.Test group is consistent with the basal diet of control group fed, the difference is that, in the feed of test group
Added with account for total feed quality 0.04% antiseptic feed additive (step (1) be made, in practical feed containing lauric acid list it is sweet
Grease 0.02%), control group only feeds basal diet.Feeding 28 days, counts the egg laying performance of laying hen, statistical result such as the following table 6
Shown (in table 6, colleague's shoulder mark difference lowercase letter indication difference is significant (P < 0.05)).
The egg laying performance of laying hen in 6 Application Example 4 of table
| Project | Control group | Test group |
| Laying rate (%) | 93.21±5.24 | 94.65±4.87 |
| Average egg weight (g/ pieces) | 60.14±3.25 | 61.43±4.13 |
| Feedstuff-egg ratio | 2.17±0.08a | 2.05±0.05b |
| Dirty egg rate (%) | 2.51±0.10a | 1.92±0.05b |
By the result in table 6 it is found that compared with the control group, the laying rate of test group improves 1.54%, and average egg weight increases
Add 2.14%, feedstuff-egg ratio significantly reduces 5.53% (P < 0.05), and dirty egg rate significantly reduces 23.50%, illustrates, this hair
The antiseptic feed additive of bright offer feeds laying hen, and Layer Production Performance can be improved, and reduces dirty egg incidence, improves in enteron aisle
Environment.
5 antiseptic feed additive of Application Example is for feeding aquatic cultivated animals
(1) lauric monoglyceride and defatted rice bran are sufficiently mixed according to the mass ratio of 1:1, are prepared into antiseptic feed and add
Add agent.
(2) 600 tail of hybridized prussian carp that weight is 17.15 ± 0.06g is chosen, 2 groups, including control group and test are randomly divided into
Group, 6 repetitions (case) of every component, every 50 tail of case.The basal diet of each group feeding is consistent, the difference is that, the feeding of test group
In material added with account for total feed quality 0.4% antiseptic feed additive (step (1) be made, contain lauric acid in practical feed
Monoglyceride 0.2%), the flavomycoin of 2mg/kg is added in the feed of control group.By 8 weeks growth tests, counts different and educate
The growth performance and enteron aisle Escherichia coli quantity of pond crucian carp, statistical result it is as shown in table 7 below (in table 7, shoulder mark difference small letter of going together
Matrix shows significant difference (P < 0.05)).Wherein, enteron aisle coliform count is detected with quantitative real-time PCR, as a result with 2-ΔΔCtMethod is for statistical analysis, and control group is set as 1.
The growth performance and enteron aisle coliform count of hybridized prussian carp in 7 Application Example 5 of table
| Project | Control group | Test group |
| Body weight increase rate | 86.75±4.35b | 93.45±3.69a |
| Specific growth rate (%) | 1.13±0.08 | 1.19±0.09 |
| Feed coefficient (%) | 2.46±0.20 | 2.41±0.19 |
| Coliform count | 0.98±0.21a | 0.66±0.06b |
It is yellow with addition by the result in table 7 it is found that feeding hybridized prussian carp using antiseptic feed additive provided by the invention
The control group of mycin is compared, and test group significantly improves the body weight increase rate 7.72% of hybridized prussian carp；Compared with the control group, significantly
Enteron aisle coliform count 32% (P < 0.05) is reduced, illustrates to educate using antiseptic feed additive provided by the invention feeding is different
Pond crucian carp can promote allogynogenetic crucian carp, reduce the quantity of enteron aisle Escherichia coli, have the function of substitute antibiotics.
The above is only a preferred embodiment of the present invention, is not intended to limit the scope of the invention, for this field
For technical staff, the invention may be variously modified and varied.All within the spirits and principles of the present invention, made any
Modification, equivalent replacement, improvement etc. should all be included within the scope of the present invention.
Claims (3)
1. a kind of antiseptic feed additive, which is characterized in that the antiseptic feed additive includes lauric monoglyceride.
2. purposes of the antiseptic feed additive as described in claim 1 in animal feed, which is characterized in that the antibacterial is raised
Feed additives are used to substitute the antibiotics additive in animal feed, the application method of the antiseptic feed additive are as follows:
The antiseptic feed additive is directly added into perfect compound feed and feeds livestock and poultry or aquatic livestock；Or,
The antiseptic feed additive is directly added into premix or concentrate feed, then by the premix or the concentrate feed
Livestock and poultry or aquatic livestock are fed after perfect compound feed is made with other feedstuffs；Or,
The antiseptic feed additive and carrier are prepared by mixing into pre-mixing agent, then by the pre-mixing agent and other feedstuffs
Livestock and poultry or aquatic livestock are fed after perfect compound feed is made；Or,
After the antiseptic feed additive and carrier are mixed and made into pre-mixing agent, premix or concentrate feed is added in the pre-mixing agent
In, livestock and poultry or aquatic products are fed after perfect compound feed then is made in the premix or the concentrate feed and other feedstuffs
Animal.
3. purposes of the antiseptic feed additive as claimed in claim 2 in animal feed, which is characterized in that the antibacterial is raised
The additive amount of feed additives is the 0.01~1.0% of the animal feed gross mass.
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| CN109363002A (en) * | 2018-12-13 | 2019-02-22 | 浙江农林大学 | A kind of freshwater crayfish feed stuff additive and its application |
| CN111011624A (en) * | 2019-12-11 | 2020-04-17 | 南昌大学 | Special coconut oil-lauric acid monoglyceride microcapsule for weaned piglets |
| CN113243454A (en) * | 2020-02-11 | 2021-08-13 | 杭州龙宇生物科技有限公司 | Feed additive and application thereof |
| CN114376122A (en) * | 2022-02-14 | 2022-04-22 | 中国海洋大学 | Feed additive for improving intestinal structure of large yellow croaker, feed and application |
| CN117461735A (en) * | 2023-11-02 | 2024-01-30 | 广东超聚和生物科技有限公司 | Feed composition with synergistic fermentation of bacterial enzymes and method for improving intestinal tracts of livestock and poultry by using feed composition |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109363002A (en) * | 2018-12-13 | 2019-02-22 | 浙江农林大学 | A kind of freshwater crayfish feed stuff additive and its application |
| CN111011624A (en) * | 2019-12-11 | 2020-04-17 | 南昌大学 | Special coconut oil-lauric acid monoglyceride microcapsule for weaned piglets |
| CN113243454A (en) * | 2020-02-11 | 2021-08-13 | 杭州龙宇生物科技有限公司 | Feed additive and application thereof |
| CN114376122A (en) * | 2022-02-14 | 2022-04-22 | 中国海洋大学 | Feed additive for improving intestinal structure of large yellow croaker, feed and application |
| CN117461735A (en) * | 2023-11-02 | 2024-01-30 | 广东超聚和生物科技有限公司 | Feed composition with synergistic fermentation of bacterial enzymes and method for improving intestinal tracts of livestock and poultry by using feed composition |
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Application publication date: 20181211 |