CN108938679A - A kind of transparent capsule and pill of Antrodia camphorata extract - Google Patents
A kind of transparent capsule and pill of Antrodia camphorata extract Download PDFInfo
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- CN108938679A CN108938679A CN201810853683.3A CN201810853683A CN108938679A CN 108938679 A CN108938679 A CN 108938679A CN 201810853683 A CN201810853683 A CN 201810853683A CN 108938679 A CN108938679 A CN 108938679A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A61K9/5057—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
Abstract
The invention discloses a kind of transparent capsule and pill of Antrodia camphorata extract, by following weight percent at being grouped as: honey 8-20%, Antrodia camphorata effective component 30-55%, superelevation Gel baits albumen powder 2-4% and gelatin surplus.The transparent capsule and pill of Antrodia camphorata extract is made of honey, Antrodia camphorata effective component, superelevation Gel baits albumen powder and gelatin by the present invention, wherein honey and gelatin are natural animal raw material, the primary raw material of superelevation Gel baits albumen powder is egg, it is harmless, and it is also beneficial to human body that honey is added, superelevation Gel baits albumen powder, which is added, not only can be improved the holding time of transparent capsule and pill at normal temperature, but also the solution rate of Antrodia camphorata extract can be improved, to improve the assimilation effect of Antrodia camphorata extract.
Description
Technical field
The present invention relates to technical field of plant extraction more particularly to a kind of transparent capsule and pills of Antrodia camphorata extract.
Background technique
Antrodia camphorata also known as cinnamomum kanahirai hay mushroom, belong to Aphyllophorales, Polyporaceae, antrodia karst, perennial gill fungus mushroom, and Latin is entitled
Antrodia camphorata is the novel species just delivered by biochemical boundary nineteen ninety.Its growth district is TaiWan, China mountain area height above sea level
Between 450-2000 meters of mountain forests, it is only grown in the rotten heartwood inner wall of the cinnamomum kanehirai trunk of peculiar a century of TaiWan, China or more.
Antrodia camphorata was the distinctive fungi of TaiWan, China in the past, was only grow in the distinctive cinnamomum kanehirai of TaiWan, China.Wild ox
Antrodia is the insular child care class tree species of TaiWan, China, and the snow mountain in big Anxi upstream cheats Cinnamomum kanahirai hay protection zone, gives birth to more than 100 strain oxen
Camphor tree forest.Antrodia camphorata is the unique weeping fungus found in cinnamomum kanehirai, but the parasitic pathogenic of Antrodia camphorata is not strong, therefore Cinnamomum kanahirai hay
Tree is seldom dead, can grow centuries.Wild Cinnamomum kanahirai hay ganoderma lucidum is uniquely rely, and the host to make a living ----TaiWan, China cinnamomum kanehirai is taken a broad view
The whole world, is only grown on the mountain area of 450 to 2000 meters of TaiWan, China height above sea level, and Cinnamomum kanahirai hay ganoderma lucidum is only grow on the rotten inner wall of cinnamomum kanehirai
Middle vacancy or the dark moist surface of the cinnamomum kanehirai fallen of withered volt, quantity is very rare, and the speed of growth is very slow, often
Only several centimeters of growth thickness of year.
Antrodia camphorata is grown on the moist surface of the rotten hollow inside of cinnamomum kanehirai dry rot or the trunk that lodges.Wild Antrodia camphorata is grown
Aged cinnamomum kanehirai, sporophore shape changeableization have plate, clock shape, horse-hof shape or tower-like；Nascent cerise, gradually length becomes
It is white, reddish tan, filbert or khaki.Antrodia camphorata gas fragranced is arduous, flat.There is wind-dispelling promoting the circulation of qi, change become silted up promoting blood circulation, middle benefit gas
Disappear knot, removing toxicity for detumescence, sedation-analgesia, antibacterial, antiviral and antitumor, promoted immunity of organisms the benefits of；For treatment stomach and intestine pain
Bitterly, diarrhea and vomiting, food poisoning, mushroom poisoning, diabetes, alcoholic liver, fatty liver, cirrhosis, liver cancer etc. are even more to have unique function
Energy.Antrodia camphorata be there are many physiologically active ingredient, such as polysaccharide body, triterpene compound, Sudismase, adenosine, protein
(containing immune protein), vitamin, microelement, nucleic acid, agglutinin, amino acid, solid liquor-saturated tired, cellulose, blood pressure stabilization substance etc..
With triterpene compound for most especially, up to 200 kinds or more, be that other mushrooms can not be compared in the effective component of Antrodia camphorata,
More than 200 kinds of triterpene compounds make Antrodia camphorata have anticancer, liver protection and other effects.Due to antrodia TaiWan, China be considered as it is unique and
Precious medicinal fungi, therefore there is high research and commercial value, and the wild fungi of TaiWan, China most expensive at present.
Under normal circumstances, when water soluble drug is absorbed by internal alimentary canal, absorptivity is directly proportional with its solution rate, mesh
Preceding absorption of the Antrodia camphorata product in alimentary canal in the market is very poor, and in order to improve the assimilation effect of Antrodia camphorata, the present invention is provided
A kind of transparent capsule and pill of the Antrodia camphorata extract of solution-type.
Summary of the invention
Technical problems based on background technology, the invention proposes a kind of transparent capsule and pills of Antrodia camphorata extract.
Technical scheme is as follows:
A kind of transparent capsule and pill of Antrodia camphorata extract, including following main component: honey, Antrodia camphorata effective component, superelevation
Gel baits albumen powder and gelatin.
Preferably, the transparent capsule and pill of the Antrodia camphorata extract, by following weight percent at being grouped as: honey 8-
20%, Antrodia camphorata effective component 30-55%, superelevation Gel baits albumen powder 2-4% and gelatin surplus.
Preferably, the Antrodia camphorata effective component is the ethanol solution containing Antrodia camphorata extract.
Preferably, in the ethanol solution containing Antrodia camphorata extract, the content of Antrodia camphorata effective component is 0.2-
1%.
Preferably, the Gel baits of the superelevation Gel baits albumen powder are 1200-1450g*cm-2。
Preferably, the preparation method of the Antrodia camphorata effective component, comprising the following steps:
A, it after Antrodia camphorata fructification appearance being cleaned up and dried, is crushed by high speed Universal pulverizer, and mistake
Sieve, obtains bacterium powder；
B, bacterium powder is weighed, is put into sodium chloride treatment fluid and impregnates 4-8h, is taken out after drying, then impregnated in Chinese medicine treatment fluid
15-24h；
C, the bacterium powder after immersion is poured into ethanol solution, carries out microwave oscillation, takes ethanol solution part, obtain containing ox
The ethanol solution of antrodia extract.
The Chinese medicine treatment fluid, including following component: glycerol, pollen pini and water；
In the step C, the volume content of ethyl alcohol is 85-98% in ethanol solution；
In the step C, the power of microwave oscillation is 8-15kHz, time 20-30min.
The invention has the beneficial effects that: the present invention using honey, Antrodia camphorata effective component, superelevation Gel baits albumen powder and
The transparent capsule and pill of Antrodia camphorata extract is made in gelatin, and wherein honey and gelatin are natural animal raw material, superelevation Gel baits albumen
The primary raw material of powder is egg, harmless, and it is also beneficial to human body to be added honey, and superelevation Gel baits albumen powder is added not
But the holding time of transparent capsule and pill at normal temperature can be improved, but also the solution rate of Antrodia camphorata extract can be improved, from
And improve the assimilation effect of Antrodia camphorata extract.
Specific embodiment
Embodiment 1:
A kind of transparent capsule and pill of Antrodia camphorata extract, by following weight percent at being grouped as: honey 16%, Antrodia camphorata
Effective component 48%, superelevation Gel baits albumen powder 3% and gelatin surplus.
The Antrodia camphorata effective component is the ethanol solution containing Antrodia camphorata extract.
In the ethanol solution containing Antrodia camphorata extract, the content of Antrodia camphorata effective component is 0.5%.
The Gel baits of the superelevation Gel baits albumen powder are 1350g*cm-2。
The preparation method of the Antrodia camphorata effective component, comprising the following steps:
A, it after Antrodia camphorata fructification appearance being cleaned up and dried, is crushed by high speed Universal pulverizer, and mistake
Sieve, obtains bacterium powder；
B, bacterium powder is weighed, is put into sodium chloride treatment fluid and impregnates 5h, is taken out after drying, then impregnated in Chinese medicine treatment fluid
18h；
C, the bacterium powder after immersion is poured into ethanol solution, carries out microwave oscillation, takes ethanol solution part, obtain containing ox
The ethanol solution of antrodia extract.
The Chinese medicine treatment fluid, including following component: glycerol, pollen pini and water；
In the step C, the volume content of ethyl alcohol is 92% in ethanol solution；
In the step C, the power of microwave oscillation is 12kHz, time 25min.
Embodiment 2:
A kind of transparent capsule and pill of Antrodia camphorata extract, by following weight percent at being grouped as: honey 20%, Antrodia camphorata
Effective component 30%, superelevation Gel baits albumen powder 4% and gelatin surplus.
The Antrodia camphorata effective component is the ethanol solution containing Antrodia camphorata extract.
In the ethanol solution containing Antrodia camphorata extract, the content of Antrodia camphorata effective component is 0.2%.
The Gel baits of the superelevation Gel baits albumen powder are 1450g*cm-2。
The preparation method of the Antrodia camphorata effective component, comprising the following steps:
A, it after Antrodia camphorata fructification appearance being cleaned up and dried, is crushed by high speed Universal pulverizer, and mistake
Sieve, obtains bacterium powder；
B, bacterium powder is weighed, is put into sodium chloride treatment fluid and impregnates 4h, is taken out after drying, then impregnated in Chinese medicine treatment fluid
24h；
C, the bacterium powder after immersion is poured into ethanol solution, carries out microwave oscillation, takes ethanol solution part, obtain containing ox
The ethanol solution of antrodia extract.
The Chinese medicine treatment fluid, including following component: glycerol, pollen pini and water；
In the step C, the volume content of ethyl alcohol is 85% in ethanol solution；
In the step C, the power of microwave oscillation is 15kHz, time 20min.
Embodiment 3:
A kind of transparent capsule and pill of Antrodia camphorata extract, by following weight percent at being grouped as: honey 8%, Antrodia camphorata
Effective component 55%, superelevation Gel baits albumen powder 2% and gelatin surplus.
The Antrodia camphorata effective component is the ethanol solution containing Antrodia camphorata extract.
In the ethanol solution containing Antrodia camphorata extract, the content of Antrodia camphorata effective component is 1%.
The Gel baits of the superelevation Gel baits albumen powder are 1200g*cm-2。
The preparation method of the Antrodia camphorata effective component, comprising the following steps:
A, it after Antrodia camphorata fructification appearance being cleaned up and dried, is crushed by high speed Universal pulverizer, and mistake
Sieve, obtains bacterium powder；
B, bacterium powder is weighed, is put into sodium chloride treatment fluid and impregnates 8h, is taken out after drying, then impregnated in Chinese medicine treatment fluid
15h；
C, the bacterium powder after immersion is poured into ethanol solution, carries out microwave oscillation, takes ethanol solution part, obtain containing ox
The ethanol solution of antrodia extract.
The Chinese medicine treatment fluid, including following component: glycerol, pollen pini and water；
In the step C, the volume content of ethyl alcohol is 98% in ethanol solution；
In the step C, the power of microwave oscillation is 8kHz, time 30min.
Comparative example 1
By the superelevation Gel baits albumen powder removal in embodiment 1, remaining proportion and preparation method are constant.
Comparative example 2
By the superelevation Gel baits albumen powder in embodiment 1 replace with Gel baits be 650 routine protein powder, remaining proportion and
Preparation method is constant.
Test 1
Tested the dissolution rate of embodiment 1-3 and comparative example 1-2 that (5 data of each sample test, are averaged below
Value), obtain following test result.
Table 1: 30 minutes dissolution rate test results of sample
By the above test data it is recognised that the result of extraction of the print of 1-3 of the present invention is very good.
Test 2
In the case where listing terms of packing, 40 DEG C, burn-in test 90 days and 24 are stored under room temperature under the conditions of 75%R.H.
Month, the sample of 1-3 of the embodiment of the present invention is basicly stable, without obvious rotten.And the sample of comparative example 1-2 in burn-in test 30 days and
It just will appear muddy, dissolution iso-metamorphism in 3 months under room temperature.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (6)
1. a kind of transparent capsule and pill of Antrodia camphorata extract, which is characterized in that including following main component: honey, Antrodia camphorata are effective
Ingredient, superelevation Gel baits albumen powder and gelatin.
2. the transparent capsule and pill of Antrodia camphorata extract as described in claim 1, which is characterized in that by following weight percent at
It is grouped as: honey 8-20%, Antrodia camphorata effective component 30-55%, superelevation Gel baits albumen powder 2-4% and gelatin surplus.
3. the transparent capsule and pill of Antrodia camphorata extract as claimed in claim 1 or 2, which is characterized in that the Antrodia camphorata is effective
Ingredient is the ethanol solution containing Antrodia camphorata extract.
4. the transparent capsule and pill of Antrodia camphorata extract as claimed in claim 3, which is characterized in that described extracts containing Antrodia camphorata
In the ethanol solution of object, the content of Antrodia camphorata effective component is 0.2-1%.
5. the transparent capsule and pill of Antrodia camphorata extract as claimed in claim 1 or 2, which is characterized in that the superelevation Gel baits
The Gel baits of albumen powder are 1200-1450g*cm-2。
6. the transparent capsule and pill of Antrodia camphorata extract as described in claim 1, which is characterized in that the Antrodia camphorata effective component
Preparation method, comprising the following steps:
A, it after Antrodia camphorata fructification appearance being cleaned up and dried, is crushed, and is sieved by high speed Universal pulverizer, obtained
To bacterium powder；
B, bacterium powder is weighed, is put into sodium chloride treatment fluid and impregnates 4-8h, is taken out after drying, then impregnate 15- in Chinese medicine treatment fluid
24h；
C, the bacterium powder after immersion is poured into ethanol solution, carries out microwave oscillation, takes ethanol solution part, obtain containing Antrodia camphorata
The ethanol solution of extract.
The Chinese medicine treatment fluid, including following component: glycerol, pollen pini and water；
In the step C, the volume content of ethyl alcohol is 85-98% in ethanol solution；
In the step C, the power of microwave oscillation is 8-15kHz, time 20-30min.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810853683.3A CN108938679A (en) | 2018-07-30 | 2018-07-30 | A kind of transparent capsule and pill of Antrodia camphorata extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810853683.3A CN108938679A (en) | 2018-07-30 | 2018-07-30 | A kind of transparent capsule and pill of Antrodia camphorata extract |
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| CN108938679A true CN108938679A (en) | 2018-12-07 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102357212A (en) * | 2011-10-12 | 2012-02-22 | 福建华尔康生物科技有限公司 | Compound product obtained through supercritical CO2 extraction, and preparation method thereof |
| CN103340397A (en) * | 2013-05-31 | 2013-10-09 | 南京年吉冷冻食品有限公司 | Nutrient gelatin pill and preparation method thereof |
| CN107279241A (en) * | 2017-06-29 | 2017-10-24 | 杨仲英 | A kind of Sugarless type fast food pumpkin pie and preparation method thereof |
-
2018
- 2018-07-30 CN CN201810853683.3A patent/CN108938679A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102357212A (en) * | 2011-10-12 | 2012-02-22 | 福建华尔康生物科技有限公司 | Compound product obtained through supercritical CO2 extraction, and preparation method thereof |
| CN103340397A (en) * | 2013-05-31 | 2013-10-09 | 南京年吉冷冻食品有限公司 | Nutrient gelatin pill and preparation method thereof |
| CN107279241A (en) * | 2017-06-29 | 2017-10-24 | 杨仲英 | A kind of Sugarless type fast food pumpkin pie and preparation method thereof |
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