CN108938496A - A kind of natural nano acne-removing composition and its application in cosmetics - Google Patents
A kind of natural nano acne-removing composition and its application in cosmetics Download PDFInfo
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- CN108938496A CN108938496A CN201811101232.0A CN201811101232A CN108938496A CN 108938496 A CN108938496 A CN 108938496A CN 201811101232 A CN201811101232 A CN 201811101232A CN 108938496 A CN108938496 A CN 108938496A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Abstract
The present invention relates to daily chemicals fields, provide a kind of natural nano acne-removing composition, according to parts by weight, raw material includes at least: 1-5 parts of Chinese medicine composition, 0.01-0.5 parts of rare earth compound, 0.01~0.25 part of nano zine oxide, 1-10 parts of tea tree extract, 1-20 parts of white Chinese rose extract, 2-8 parts of aloe extract, 2-10 parts of vitamin, 2-8 parts of marine algae extract, 30-60 parts of glycerol.
Description
Technical field
The present invention relates to daily chemicals fields, further relate to a kind of natural nano acne-removing composition and its application in cosmetics.
Background technique
Acne is that one kind of acne is commonly called as, also known as " whelk ", " dark sore ", " acne ", is the one kind for betiding hair follicle cutaneous gland
Chronic inflammation disease seriously affects the appearance and heart of people.It is now recognized that the morbidity of acne and Serum Testosterone Levels, sebum
Secretion increase, the infection of hair follicle conduit hyperkeratinization, propionibacterium acnes are related.In addition, majority are isolated using sun screen now
Ultraviolet light dust, if but sun screen is unclean carefully to directly result in the dark and gloomy shortage healthy glow of skin, skin quality relaxation is grown
Raw dark sore, long acne, especially for Oily everybody, the dust that skin of face easily adsorbs in air more causes the life of acne
It is long.Doctor trained in Western medicine mainly uses male sex hormone antagonist, antibiotic, tretinoin medicines to treat the disease, and curative effect determines, but toxic side effect
Obviously, such as the damage of hepatic and renal function, teratogenesis, thus the product for resolving poxes that can safely, effectively treat acne has become a hot topic of research.
It is numerous to treat acne anti-acne research and development product, including the fields such as drug, cosmetics, cosmetic field needs pure day at present
So, no hormone, curative effect is rapidly and significant, does not recur, is not easy to adsorb harmful substance and have no toxic side effect, can thoroughly cure acne
Product.
Summary of the invention
In order to solve the above-mentioned technical problem, the first aspect of the invention provides a kind of natural nano acne-removing composition,
According to parts by weight, raw material includes at least: 1-5 parts of Chinese medicine composition, 0.01-0.5 parts of rare earth compound, nano zine oxide 0.01
~0.25 part, 1-10 parts of tea tree extract, 1-20 parts of white Chinese rose extract, 2-8 parts of aloe extract, 2-10 parts of vitamin, sea
2-8 parts of algae extract, 30-60 parts of glycerol.
In some embodiments, the Chinese medicine composition, rare earth compound, the weight ratio between nano zine oxide are
1:(0.01~0.1): (0.01~0.05).
In some embodiments, the raw materials of traditional Chinese medicine composition includes yunnan euonymus root and stem 0.005-0.5 by weight
Part, 0.5-1 parts of Radix Glycyrrhizae, 0.5-1 parts of Astragalus Root P.E, 1-2 parts of white lilac, 0.1-2 parts of Paris polyphylla, 0.1-1 parts of Leonurus extract,
1-2 parts of mung bean flour, 0.5-1 parts of fortune paulownia flower, 0.5-2 parts of wormwood, 0.1-1 parts of Radix Angelicae Sinensis, 0.1-2 parts of Lepisorus thunbergianus (Kaulf.) Ching.
In some embodiments, the weight ratio of the rare earth compound and yunnan euonymus root and stem is 1:(0.5~1).
In some embodiments, the rare earth compound is rare earth chloride and/or rare earth oxide.
In some embodiments, the rare earth chloride is lanthanum chloride and/or cerium chloride；The rare earth oxide is oxidation
Cerium and/or lanthana.
In some embodiments, the weight ratio of the tea tree extract and white Chinese rose extract is 1:(1~2).
In some embodiments, the nanometer particle size of the nano zine oxide is 45nm~100nm.
The second aspect of the invention provides a kind of preparation method of natural nano acne-removing composition, and step is at least wrapped
It includes:
(1) preparation just mixes object: pressing load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, sea
Algae extract is uniformly mixed, and addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, bone
Board grass, preliminary coarse crushing are crushed using micronizer later, with 400~800 meshes after crushed, obtain the powder of Chinese herbal medicine
Last mixture is added Chinese medicine composition remaining ingredient, rare earth compound and nano zine oxide, reuses ultramicro-vibration pulverizer,
Smash it through 1500~2000 meshes；Nanometer pulverization is finally carried out using the shearing ultra-fine grinding instrument of high speed centrifugation and obtains nanoscale
The traditional Chinese medicinal components of supported rare earth element；
(3) prepare natural nano acne-removing composition: by the traditional Chinese medicinal components of step (2) nanoscale load rare earth element be added to
(1) it just mixes in object, under the conditions of 80~100MPa pressure, 60~70 DEG C of temperature, carries out high pressure homogenizer and recycle homogeneous 10~20
It is secondary, obtain natural nano acne-removing composition.
The third aspect of the invention provides a kind of application of natural nano acne-removing composition, is applied to cosmetics and leads
Domain.
In some embodiments, the natural nano acne-removing composition can be applied to facial cleanser, facial mask, toner, cream
Liquid, face cream, Essence, makeup remover, toner, clarifying lotion.
Beneficial effects of the present invention:
(1) the present invention provides a kind of natural nano acne-removing compositions, and natural nano grade particle composition can be effective
It is deep into subcutaneous tissue, is played a role, quick therapeutic effect can reach to the acne generated, acne print can be desalinated or even is disappeared
The effect removed, it is non-stimulated, it is without side-effects, show extremely significant beneficial effect.
(2) present invention is used in compounding using white Chinese rose extract and tea tree extract, have the function of it is mutually coordinated, can be with
Anti-inflammation and sterilization is played to skin, detoxication, activating microcirculation and removing stasis medicinal, reducing the red and swollen aspect of acne has apparent effect.
(3) nanoscale Chinese medicine supported rare earth element is used in the present invention, due to reuniting after Chinese medicine composition mixing, point
Unevenness is dissipated, when the nano zine oxide that a certain amount of granularity is 45nm~100nm is added, rare earth compound is can solve and divides in Chinese medicine
Non-uniform problem is dissipated, can achieve and only need a small amount of rare earth element, so that it may in the mixed system being dispersed in, inhibition can be played
Absorption of the face to harmful dust in air is absorbed, has extremely significant beneficial effect.
(4) Chinese medicine of supported rare earth element Nano grade, the combination of the two can promote to expand capillary, can be from trouble
Metabolism and blood circulation are adjusted in person's body, prevent the recurrence again of acne.
The above-mentioned of the application and other features, aspects and advantages are more readily understood with reference to following detailed description.
Specific embodiment
Unless otherwise indicated, from context cues or belong to the convention of the prior art, otherwise number all in the application
It is all based on weight with percentage, and test and characterizing method used is all synchronous with the submission date of the application.If existing
There is defining for the concrete term disclosed in technology inconsistent with any definition provided herein, then with provided herein
Subject to term definition.
It is further clear, complete that the technical characteristic work in technical solution is provided to the present invention With reference to embodiment
Description, not to the limitation of its protection scope.
Word " preferred ", " preferably ", " preferred " in the present invention etc. refer to, can provide certain in some cases
The embodiment of the present invention of a little beneficial effects.However, other embodiments may also under identical circumstances or in the case of other
It is preferred.In addition, not implying that other embodiments are unavailable to the statement of one or more preferred embodiments, it is not yet
It is intended to exclude other embodiments except the scope of the present invention.
The first aspect of the invention provides a kind of natural nano acne-removing composition, and according to parts by weight, raw material is at least
Include: 1-5 parts of Chinese medicine composition, 0.01-0.5 parts of rare earth compound, 0.01~0.25 part of nano zine oxide, tea tree extract 1-
10 parts, 1-20 parts of white Chinese rose extract, 2-8 parts of aloe extract, 2-10 parts of vitamin, 2-8 parts of marine algae extract, glycerol 30-
60 parts.
Preferably, a kind of natural nano acne-removing composition, according to parts by weight, raw material includes at least: Chinese traditional medicine composition
2-4 parts of object, 0.06-0.28 parts of rare earth compound, 0.04~0.16 part of nano zine oxide, 3-7 parts of tea tree extract, white Chinese rose mention
Take 3-12.6 parts of object, 4-6 parts of aloe extract, 4-8 parts of vitamin, 4-6 parts of marine algae extract, 40-50 parts of glycerol.
It is further preferred that a kind of natural nano acne-removing composition, according to parts by weight, raw material is included at least: in
3 parts of drug composition, 0.15 part of rare earth compound, 0.9 part of nano zine oxide, 5 parts of tea tree extract, 7.5 parts of white Chinese rose extract,
5 parts of aloe extract, 6 parts of vitamin, 5 parts of marine algae extract, 45 parts of glycerol.
In some embodiments, the Chinese medicine composition, rare earth compound, the weight ratio between nano zine oxide are
1:(0.01~0.1): (0.01~0.05)；Preferably, the Chinese medicine composition, rare earth compound, between nano zine oxide
Weight ratio is 1:(0.03~0.0.07): (0.02~0.04)；It is further preferred that the Chinese medicine composition, rare earth chemical combination
Weight ratio between object, nano zine oxide is 1:0.05:0.03.
Chinese medicine composition
In some embodiments, the raw materials of traditional Chinese medicine composition includes yunnan euonymus root and stem 0.005-0.5 by weight
Part, 0.5-1 parts of Radix Glycyrrhizae, 0.5-1 parts of Astragalus Root P.E, 1-2 parts of white lilac, 0.1-2 parts of Paris polyphylla, 0.1-1 parts of Leonurus extract,
1-2 parts of mung bean flour, 0.5-1 parts of fortune paulownia flower, 0.5-2 parts of wormwood, 0.1-1 parts of Radix Angelicae Sinensis, 0.1-2 parts of Lepisorus thunbergianus (Kaulf.) Ching.
Preferably, the raw materials of traditional Chinese medicine composition includes 0.12 part of yunnan euonymus root and stem, 0.8 part of Radix Glycyrrhizae, Radix Astragali by weight
0.8 part of extract, 1.5 parts of white lilac, 1 part of Paris polyphylla, 0.5 part of Leonurus extract, 1.5 parts of mung bean flour, 0.8 part of fortune paulownia flower, Chinese mugwort
Careless 1 part, 0.5 part of Radix Angelicae Sinensis, 1 part of Lepisorus thunbergianus (Kaulf.) Ching.
In the present invention, each component in Chinese medicine composition is described below:
Yunnan euonymus root and stem: Celastraceae burning buss Yunnan winged euonymus Euonymus yunnanensis Franch, it is slight bitter, puckery,
Temperature, promoting blood circulation to remove blood stasis, wind-damp dispelling, eliminating stasis to subdue swelling cure mainly traumatic injury, waist ship pain, rheumatalgia pain.
Yunnan euonymus root and stem can purchase in Qi agricultural trade Co., Ltd of township in the application, can also buy in other companies.
Radix Glycyrrhizae: for glycyrrhizic legume Glycyrrhiza uralensis Fisch., swollen fruit Radix Glycyrrhiza
The dry root of inflata Bat. or glycyrrhiza glabra Glycyrrhiza glabra L..Alias state is old, Herba Hedyotis cantonensis, Glycyrrhiza Uralensis,
Sweet tea root, root is sturdy with rhizomes, is a kind of help Chinese herbal medicine, and medicinal part is root and rhizome, glycyrrhizin and flavonoids object
Matter is most important physiological activator in Radix Glycyrrhizae, and licoflavone class has the function of mildly inhibiting tyrosinase, and Radix Glycyrrhizae is extracted
Object has been found to be most effective plant whitening agent at present.Radix Glycyrrhizae has excellent anti-inflammatory, anti-allergic effects, because containing in Radix Glycyrrhizae
Glycyrrhizin is a kind of compound of similar hormone, it helps to balance the intracorporal hormone-content of women.With preferable whitening skin
The effect of skin.
Astragalus Root P.E: Astragalus Root P.E is leguminous mongolian scutellaria Astragalus membranaceus
(Fisch.) Bge.var.mongholicus (Bge.) Hsiao or Astragalus membranacus Astragalus membranaceus
(Fisch.) the drying root extract of Bge. mainly contains several constituents such as saponin(e, flavones, astragalus polyose and amino acid, yellow
Astragalus polysaccharides have an obvious antagonism to tubercle bacillus affection, Radix Astragali have tonifying Qi and lifting yang, strengthening exterior and reducing sweat, pus draining and toxin expelling, inducing diuresis for removing edema,
The effect of expelling pus and promoting granulation, strengthen immunity enhance energy, antifatigue, anti-mutation, and liver protection inhibits the effect of osteoclast.It is modern
Pharmacological research shows that Radix Astragali has an enhancing body's immunity, and heart tonifying decompression, anti-aging, antifatigue, anti-is swollen at hypoglycemic, diuresis
Tumor, it is antiviral, calm, analgesia the effects of.Radix Astragali acts on humoral immunity, has obvious rush to the antibody tormation function of normal body
Into effect.No. CAS: 84687-43-4.
White lilac: the Passeriformes ploceidae tree sparrow, white lilac can purchase in Bo in Passer montanus (L.) the application
Chen Yuan, state city medicinal material stack, also can purchase in other companies.
Paris polyphylla: for the rhizome of liliaceous plant Yunnan Rhizoma Paridis Paris yunnanensis Franch..Its bitter, property are micro-
It is cold.There is clearing heat and detoxicating a, swelling and pain relieving, pathopyretic ulcer is controlled in the effect of cool liver is calmed the frightened, and honeysuckle compatibility application, antibacterial, anti-inflammatory,
It is antiviral, antipruritic, analgesic.
Paris polyphylla can purchase in Bozhou City Huimin Chinese medicine wholesale house in the application, also can purchase in other companies.
Leonurus extract: for the fresh of Lamiaceae plant motherwort Leonurus japonicus Houtt. or drying
Aerial part, it is bitter, pungent, it is slightly cold.Return liver, pericardium, bladder meridian.Motherwort contains various trace elements.Selenium has enhancing immune thin
Born of the same parents' vigor, the generation for mitigating atherosclerosis and the effect for improving human body defence function of diseases system；Manganese can be anti-oxidant, anti-
Aging, hyperplasia that is antifatigue and inhibiting cancer cell.So the beneficial face beauty of motherwort energy, anti-aging, removing blood stasis for promoting tissue regeneration, promoting blood circulation are adjusted
Through inducing diuresis to remove edema is clearing heat and detoxicating.For irregular menstruation, dysmenorrhea menostasis, lochiorrhagia, edema and little urine, sore swollen toxin.No. CAS:
4136-37-2。
Mung bean flour: the powder that pulse family Kidney bean platymiscium mung bean Phaseolus radiatus L. is worn into is mung bean flour, taste
It is sweet, cold in nature, play the role of it is clearing heat and detoxicating, relieve summer heat, diuresis, anti-acne, pharmacological action is reducing blood lipid, norcholesterol, antiallergy, anti-
Bacterium, it is antitumor, whet the appetite, liver protection shield kidney；There is bacteriostasis, body's immunity can be enhanced, there is antiallergy and supplement
The effect of moisture.Mung bean has protein, fat, carbohydrate, vitamin B1, B2, carrotene, Niacin, folic acid, mineral
Matter calcium, phosphorus, iron.
Mung bean flour can purchase in the pure emerging hall Chinese medicine sale Co., Ltd of Bozhou City in the application, also can purchase in other public affairs
Department.
Fortune paulownia flower: the flower of ketone, Paulownia fortunei (Seem.) Hemsl. tool are steeped for scrophulariaceae paulownia or hair
There is the effect of antibacterial bacteriostatic, hemostasis and anti-inflammation, the extractable antibacterial substance out of both substances, for treating inflammation, virus
Infection, tinea of feet and hands, boil and burn etc. have inhibitory effect to staphylococcus aureus and hay bacillus.
Fortune paulownia flower can purchase in Bozhou City Hong Tai pharmaceutcal corporation, Ltd in the application, also can purchase in other companies.
Wormwood: for composite family Artemisia argyi H.L é v.&Vaniot, invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing,
Relieving spasm to stop pain, coordinating the drug actions of a prescription, all herbal medicine have Wen Jing, dry, cold dispelling, hemostasis, anti-inflammatory, relieving asthma, cough-relieving, miscarriage prevention, antiallergy etc.
Effect.
Wormwood can purchase in the Nanyang ridge Lao Ai wormwood Products Co., Ltd in the application, also can purchase in other companies.
Radix Angelicae Sinensis: for Umbelliferae Angelica sinensis (Oliv.) Diels, nature and flavor are sweet, pungent, warm, return liver, the heart, the spleen channel,
With enriching blood, invigorate blood circulation, cool blood, activating microcirculation and removing stasis medicinal, promoting eruption of detoxifying, menstruction regulating and pain relieving, moisturizing dryness and lubricating intestine effect.Cure mainly all cards of the deficiency of blood, menstruation
Uncomfortable, menostasis, dysmenorrhea, abdominal mass knot is poly-, and metrorrhagia and metrostaxis, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness, intestines are dry and shit is difficult, weight, ulcer sore after dysentery with bloody stool
Ulcer, injury from falling down.
Radix Angelicae Sinensis can purchase in one hundred Run Tang pharmaceutcal corporation, Ltd of Bozhou City in the application, also can purchase in other companies.
Lepisorus thunbergianus (Kaulf.) Ching: for Polypodiaceae subfam. Microsoroideae Cyclosorus plant Jiangnan star fern Microsorium fortune (Moore) Ching, clearly
Hot dampness removing, cooling blood and hemostasis, swelling and pain relieving.For jaundice, dysentery, urinary tract infections, scrofula, leukorrhea, rheumatic arthritis, cough
Blood is spitted blood, hematochezia, bleeding from five sense organs or subcutaneous tissue；Traumatic injury is controlled in external application, fracture, venomous snake bite, furuncle swelling toxin.It has been found that Chinese medicine composition
Middle addition Lepisorus thunbergianus (Kaulf.) Ching and fortune paulownia flower are used in compounding, and also function to beneficial effect to acne symptom decrease.
Lepisorus thunbergianus (Kaulf.) Ching can purchase in Anhui Fu Chuntang prepared slices of Chinese crude drugs Co., Ltd in the application, also can purchase in other companies.
Rare earth compound
In some embodiments, the weight ratio of the rare earth compound and yunnan euonymus root and stem is 1:(0.5~1)；Preferably,
The weight ratio of the rare earth compound and yunnan euonymus root and stem is 1:(0.7~0.9)；It is further preferred that the rare earth compound and
The weight ratio of yunnan euonymus root and stem is 1:0.8.
In some embodiments, the rare earth compound is rare earth chloride and/or rare earth oxide.
In some embodiments, the rare earth chloride is lanthanum chloride and/or cerium chloride.
In some embodiments, the rare earth oxide is cerium oxide and/or lanthana.
In some preferred embodiments, the rare earth compound is cerium chloride.
Nanoscale Chinese medicine supported rare earth element is used in the present invention, is gone out after being mixed due to Chinese medicine composition with rare earth compound
Now reunite, dispersion is uneven, when the nano zine oxide that a certain amount of granularity is 45nm~100nm is added, can solve rare earth compound
Disperse non-uniform problem in Chinese medicine, can achieve and only need a small amount of rare earth element, so that it may in the mixed system being dispersed in, energy
The absorption for inhibiting face to harmful dust in air is absorbed enough is played, there is extremely significant beneficial effect.
Tea tree extract
Tea tree extract has the function of acne-removing inflammation-diminishing, oil-control convergence, reinforced immunological power, antibacterial, can effectively antagonize Cuo
Small pox caused by sore Propionibacterium.No. CAS: 85085-48-9.
Bai Yueji extract
In some embodiments, the weight ratio of the tea tree extract and white Chinese rose extract is 1:(1~2)；It is preferred that
, the weight ratio of the tea tree extract and white Chinese rose extract is 1:(1.2~1.8)；It is further preferred that the tea tree mentions
Taking the weight ratio of object and white Chinese rose extract is 1:1.5.
China rose: being a kind of common rosaceae Rosa Chinese herbal medicine also known as Chinese rose perpetual bloom, and Chinese medicine thinks its nature and flavor
Gan Wen has the effect of promoting blood circulation for regulating menstruation, subdhing swelling and detoxicating, cures mainly irregular menstruation, dysmenorrhea, ulcerative carbuncle pyogenic infections, scrofula etc..Human body it is more
Kind of disease and to cross presenility eliminated excessive in vivo since oxygen radical excessive in vivo causes normal cell Oxidative demage
Free radical be delay skin aging important channel.The extract of China rose has the ability for removing DPPH free radical, resists
Oxidation increases with extract concentrations and is gradually increased, and the phenolic substancess such as contained Quercetin, tannin, gallic acid can capture
Oxyradical blocks the progress of peroxidating chain reaction and inhibits Oxidation of Fat and Oils.Wherein China rose can be divided into white Chinese rose, the red moon
Season, powder Chinese rose, yellow Chinese rose.
Bai Yueji extract is primarily referred to as the extract that the flower of white Chinese rose is obtained by certain solvent extraction, with other face
Color Chinese rose extract is compared, and has more excellent effect, it is found by the applicant that other color Chinese rose extracts and tea tree
Extract is used in compounding, and by mutually coordinated effect, although playing anti-inflammation and sterilization, detoxication to skin, activating microcirculation and removing stasis medicinal subtracts
Small acne redness has certain effect, and still, white China rose and tea tree extract are used in compounding, and mutually coordinated effect is more
Significantly, it is special to have the effect of, in the anti-inflammation and sterilization of skin, detoxication, activating microcirculation and removing stasis medicinal reduces effect in terms of acne redness effect
Fruit is significant.
Can being prepared by alcohol extraction procedure for the white Chinese rose extract, can also be prepared by other methods.
Other described color Chinese rose extracts include but is not limited to that red Chinese rose extract, powder Chinese rose extract, yellow Chinese rose mention
Object is taken, can be prepared by alcohol extraction procedure, can also be prepared by other methods.
The alcohol extraction procedure, the preparation method is as follows:
It is constant that Chinese rose petal is dried to moisture, is crushed, sieving, the second for being then 65wt% with concentration at 70~85 DEG C
Alcohol extracts 3h, and extracting solution filtering is concentrated into medicinal extract, obtains Fols Rosae extract.
Nano zine oxide
In some embodiments, the nanometer particle size of the nano zine oxide is 45nm~100nm；Preferably, described to receive
The nanometer particle size of rice zinc oxide is 55nm~80nm；It is further preferred that the nanometer particle size of the nano zine oxide is 70nm.
The nano zine oxide is purchased from Lanzhou the Yellow River zinc-magnesium sodium rice Materials Research Laboratories, can also be obtained by other means
?.
Aloe extract
For the anthraquinone analog compound of aloe with skin contraction, softness, the performance of moisturizing, anti-inflammatory, bleaching is made, there are also release
Hardening, angling, the effect for improving scar, can not only prevent small wrinkle, eye pouch, cutis laxa, moreover it is possible to keep skin wet, spoil
It is tender, at the same time it can also treat scytitis, also there is good treatment to acne, freckle, acne and scald, knife wound, insect bite etc.
Effect has the function of sterilization, antibacterial, anti-inflammatory, removing toxic substances, promotes wound healing, can effectively eliminate acne, acne, clinically
It is significant in efficacy for treating inflammation, it is similarly effective to hair, hair holding can be made to moisten smooth, prevented hair loss.CAS
Number: 85507-69-3.
Vitamin
Vitamin is one kind organic compound necessary to maintaining health.This substance in vivo neither constitute body
The raw material of body tissue, nor the source of energy, but a kind of Auto-regulator, its important function in metabolism.
Vitamin includes but is not limited to vitamin A, vitamin B, vitamin C, vitamin E.
Marine algae extract
Marine algae extract is a kind of pure natural marine organisms product, and all features are all from this special seaweed sheet
Body contains phycocolloid acid, crude protein, multivitamin, enzyme and microelement in it, and amino acid and mucopolysaccharide rich in etc. are sugared
Aldehyde derivatives and algae essence polymer have good moisturizing, lubrication and crease-resistant effect to skin.No. CAS: 3351-86-8.
Glycerol
Glycerol also known as glycerine, glycerol are in cosmetics using most common moisturizer, contain in drier oil molecule there are three-
OH can form hydrogen bond with hydrone, can firmly lock hydrone, play moistening effect, and glycerol is for the skin of human body
Tissue and hair tissue have apparent moisturizing effect, can increase the dissolubility of cosmetics, it is easier to permeate.No. CAS: 56-81-
5。
The second aspect of the invention provides a kind of preparation method of natural nano acne-removing composition, and step is at least wrapped
It includes:
(1) preparation just mixes object: pressing load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, sea
Algae extract is uniformly mixed, and addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, bone
Board grass, preliminary coarse crushing are crushed using micronizer later, are added after crushed with 400~800 meshes, are obtained Chinese herbal medicine
Mixture of powders, Chinese medicine composition remaining ingredient is added, rare earth compound and nano zine oxide reuse ultra micro vibration and crush
Machine smashes it through 1500~2000 meshes；Finally nanometer pulverization is carried out using the shearing ultra-fine grinding instrument of high speed centrifugation to be received
The traditional Chinese medicinal components of meter level supported rare earth element；
(3) prepare natural nano acne-removing composition: by the traditional Chinese medicinal components of step (2) nanoscale load rare earth element be added to
(1) it just mixes in object, under the conditions of 80~100MPa pressure, 60~70 DEG C of temperature, carries out high pressure homogenizer and recycle homogeneous 10~20
It is secondary, obtain natural nano acne-removing composition.
As a preferred embodiment, the preparation method of natural nano acne-removing composition, step include at least:
(1) preparation just mixes object: pressing load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, sea
Algae extract is uniformly mixed, and addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, bone
Board grass, preliminary coarse crushing are crushed using micronizer later, are added after crushed with 600 meshes, are obtained the powder of Chinese herbal medicine
Mixture is added Chinese medicine composition remaining ingredient, rare earth compound and nano zine oxide, reuses ultramicro-vibration pulverizer, powder
1800 meshes are crossed after broken；Nanometer pulverization is finally carried out using the shearing ultra-fine grinding instrument of high speed centrifugation and obtains nanoscale load rare earth
The traditional Chinese medicinal components of element；
(3) prepare natural nano acne-removing composition: by the traditional Chinese medicinal components of step (2) nanoscale load rare earth element be added to
(1) it just mixes in object, under the conditions of 90MPa pressure, 65 DEG C of temperature, carries out high pressure homogenizer and recycle homogeneous 15 times, naturally received
Rice acne-removing composition.
In some embodiments, the average grain diameter of the natural nano acne-removing composition is 40nm-90nm；Preferably,
The average grain diameter of the natural nano acne-removing composition is 50nm-80nm；It is further preferred that the natural nano anti-acne combination
The average grain diameter of object is 65nm.
It has been found that natural nano grade particle composition described herein can effectively be deep into subcutaneous tissue,
It plays a role, quick therapeutic effect can reach to the acne generated, the effect that acne print even is eliminated can be desalinated, it is stingless
Swash, it is without side-effects, show extremely significant beneficial effect.
The test method of the average grain diameter of the natural nano acne-removing composition is measured using transmission electron microscopy, is adopted
With its particle size of Hitachi's H-600 determination of transmission electron microscopy.
The specific test method is as follows for the transmission electron microscopy:
First by nanometer acne-removing composition drop on the copper mesh with carbon film, after the carrier fluid glycerol volatilization in solution, it is put into
Sample stage shoots representational digital electrochromic mirror as several.A is had chosen, the tri- groups of nanoparticle subgroups B, C are shot, then
It is randomly selected in every photo and measures 50 nano particle diameters, average grain diameter is calculated by formula 1.
∑ n-selection is tested the population in Nano particles of calcium carbonate group；
∑ nD-is tested the summation of whole nano particle diameters of Nano particles of calcium carbonate.
The third aspect of the invention provides a kind of application of natural nano acne-removing composition, is applied to cosmetics and leads
Domain.
In some preferred embodiments, the natural nano acne-removing composition can be applied to facial cleanser, facial mask, skin toner
Water, lotion, face cream, Essence, makeup remover, toner, stoste, clarifying lotion.
If raw materials used to be all commercially available without other explanations, it is purchased from traditional Chinese medicines chemical reagent.
The present invention is specifically described below by embodiment.Following embodiment is served only for making furtherly the present invention
It is bright, it should not be understood as the limitation to the present invention, protection, professional and technical personnel in the field makes according to the content of foregoing invention
Nonessential modifications and adaptations, still fall within protection scope of the present invention.
Embodiment 1
A kind of natural nano acne-removing composition, according to parts by weight, raw material includes:
1 part of Chinese medicine composition, 0.01 part of cerium oxide, 0.01 part of nano zine oxide, 1 part of tea tree extract, white Chinese rose are extracted
1 part of object, 2 parts of aloe extract, 2 parts of vitamin, 2 parts of marine algae extract, 30 parts of glycerol.
The raw materials of traditional Chinese medicine composition includes 0.005 part of yunnan euonymus root and stem, 0.5 part of Radix Glycyrrhizae, astragalus extraction according to parts by weight
0.5 part of object, 1 part of white lilac, 0.1 part of Paris polyphylla, 0.1 part of Leonurus extract, 1 part of mung bean flour, 0.5 part of fortune paulownia flower, wormwood 0.5
Part, 0.1 part of Radix Angelicae Sinensis, Lepisorus thunbergianus (Kaulf.) Ching are 0.1 part.
The particle size of the nano zine oxide is 45nm.
A kind of preparation method of natural nano acne-removing composition, step include:
(1) preparation just mixes object: pressing load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, sea
Algae extract is uniformly mixed, and addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, bone
Board grass, preliminary coarse crushing are crushed using micronizer later, with 400 meshes after crushed, obtain the powder mixing of Chinese herbal medicine
Object is added Chinese medicine composition remaining ingredient, rare earth compound and nano zine oxide, ultramicro-vibration pulverizer is reused, after crushing
Cross 1500 meshes；Nanometer pulverization is finally carried out using the shearing ultra-fine grinding instrument of high speed centrifugation and obtains nanoscale load rare earth element
Traditional Chinese medicinal components；
(3) prepare natural nano acne-removing composition: by the traditional Chinese medicinal components of step (2) nanoscale load rare earth element be added to
(1) it just mixes in object, under the conditions of 80MPa pressure, 60 DEG C of temperature, carries out high pressure homogenizer and recycle homogeneous 10 times, naturally received
Rice acne-removing composition.
Embodiment 2
A kind of natural nano acne-removing composition, according to parts by weight, raw material includes:
2 parts of Chinese medicine composition, 0.14 part of lanthanum chloride, 0.08 part of nano zine oxide, 3 parts of tea tree extract, white Chinese rose are extracted
3.6 parts of object, 4 parts of aloe extract, 4 parts of vitamin, 4 parts of marine algae extract, 40 parts of glycerol.
The raw materials of traditional Chinese medicine composition includes 0.098 part of yunnan euonymus root and stem, 0.8 part of Radix Glycyrrhizae, 0.8 part of Astragalus Root P.E, illiterate person
Fragrant 1.5 parts, 1 part of Paris polyphylla, 0.5 part of Leonurus extract, 1.5 parts of mung bean flour, 0.8 part of fortune paulownia flower, 1 part of wormwood, 0.5 part of Radix Angelicae Sinensis,
1 part of Lepisorus thunbergianus (Kaulf.) Ching.
The particle size of the nano zine oxide is 55nm.
A kind of preparation method of natural nano acne-removing composition, step include:
(1) preparation just mixes object: pressing load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, sea
Algae extract is uniformly mixed, and addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, bone
Board grass, preliminary coarse crushing are crushed using micronizer later, with 400 meshes after crushed, obtain the powder mixing of Chinese herbal medicine
Object is added Chinese medicine composition remaining ingredient, rare earth compound and nano zine oxide, ultramicro-vibration pulverizer is reused, after crushing
Cross 1500 meshes；Nanometer pulverization is finally carried out using the shearing ultra-fine grinding instrument of high speed centrifugation and obtains nanoscale load rare earth element
Traditional Chinese medicinal components；
(3) prepare natural nano acne-removing composition: by the traditional Chinese medicinal components of step (2) nanoscale load rare earth element be added to
(1) it just mixes in object, under the conditions of 80MPa pressure, 60 DEG C of temperature, carries out high pressure homogenizer and recycle homogeneous 10 times, naturally received
Rice acne-removing composition.
Embodiment 3
A kind of natural nano acne-removing composition, according to parts by weight, raw material includes:
4 parts of Chinese medicine composition, 0.12 part of lanthanum chloride, 0.08 part of nano zine oxide, 7 parts of tea tree extract, white Chinese rose are extracted
12.6 parts of object, 6 parts of aloe extract, 8 parts of vitamin, 6 parts of marine algae extract, 50 parts of glycerol.
The raw materials of traditional Chinese medicine composition includes 0.108 part of yunnan euonymus root and stem, 0.8 part of Radix Glycyrrhizae, 0.8 part of Astragalus Root P.E, illiterate person
Fragrant 1.5 parts, 1 part of Paris polyphylla, 0.5 part of Leonurus extract, 1.5 parts of mung bean flour, 0.8 part of fortune paulownia flower, 1 part of wormwood, 0.5 part of Radix Angelicae Sinensis,
1 part of Lepisorus thunbergianus (Kaulf.) Ching.
The particle size of the nano zine oxide is 80nm.
A kind of preparation method of natural nano acne-removing composition, step include:
(1) preparation just mixes object: pressing load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, sea
Algae extract is uniformly mixed, and addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, bone
Board grass, preliminary coarse crushing are crushed using micronizer later, with 800 meshes after crushed, obtain the powder mixing of Chinese herbal medicine
Object is added Chinese medicine composition remaining ingredient, rare earth compound and nano zine oxide, ultramicro-vibration pulverizer is reused, after crushing
Cross 2000 meshes；Nanometer pulverization is finally carried out using the shearing ultra-fine grinding instrument of high speed centrifugation and obtains nanoscale load rare earth element
Traditional Chinese medicinal components；
(3) prepare natural nano acne-removing composition: by the traditional Chinese medicinal components of step (2) nanoscale load rare earth element be added to
(1) it just mixes in object, under the conditions of 100MPa pressure, 70 DEG C of temperature, carries out high pressure homogenizer and recycle homogeneous 20 times, naturally received
Rice acne-removing composition.
Embodiment 4
A kind of natural nano acne-removing composition, according to parts by weight, raw material includes:
5 parts of Chinese medicine composition, 0.5 part of cerium chloride, 0.25 part of nano zine oxide, 10 parts of tea tree extract, white Chinese rose are extracted
20 parts of object, 8 parts of aloe extract, 10 parts of vitamin, 8 parts of marine algae extract, 60 parts of glycerol.
The raw materials of traditional Chinese medicine composition include 0.5 part of yunnan euonymus root and stem, 1 part of Radix Glycyrrhizae, 1 part of Astragalus Root P.E, 2 parts of white lilac,
2 parts of Paris polyphylla, 1 part of Leonurus extract, 2 parts of mung bean flour, 1 part of fortune paulownia flower, 2 parts of wormwood, 1 part of Radix Angelicae Sinensis, 2 parts of Lepisorus thunbergianus (Kaulf.) Ching.
The particle size of the nano zine oxide is 100nm.
A kind of preparation method of natural nano acne-removing composition, step include:
(1) preparation just mixes object: pressing load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, sea
Algae extract is uniformly mixed, and addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, bone
Board grass, preliminary coarse crushing are crushed using micronizer later, with 800 meshes after crushed, obtain the powder mixing of Chinese herbal medicine
Object is added Chinese medicine composition remaining ingredient, rare earth compound and nano zine oxide, ultramicro-vibration pulverizer is reused, after crushing
Cross 2000 meshes；Nanometer pulverization is finally carried out using the shearing ultra-fine grinding instrument of high speed centrifugation and obtains nanoscale load rare earth element
Traditional Chinese medicinal components；
(3) prepare natural nano acne-removing composition: by the traditional Chinese medicinal components of step (2) nanoscale load rare earth element be added to
(1) it just mixes in object, under the conditions of 100MPa pressure, 70 DEG C of temperature, carries out high pressure homogenizer and recycle homogeneous 20 times, naturally received
Rice acne-removing composition.
Embodiment 5
A kind of natural nano acne-removing composition, according to parts by weight, raw material includes:
3 parts of Chinese medicine composition, 0.15 part of cerium chloride, 0.09 part of nano zine oxide, 5 parts of tea tree extract, white Chinese rose are extracted
7.5 parts of object, 5 parts of aloe extract, 6 parts of vitamin, 5 parts of marine algae extract, 45 parts of glycerol.
The raw materials of traditional Chinese medicine composition includes 0.12 part of yunnan euonymus root and stem, 0.8 part of Radix Glycyrrhizae, 0.8 part of Astragalus Root P.E, white lilac
1.5 parts, 1 part of Paris polyphylla, 0.5 part of Leonurus extract, 1.5 parts of mung bean flour, 0.8 part of fortune paulownia flower, 1 part of wormwood, 0.5 part of Radix Angelicae Sinensis, bone
1 part of board grass.
The particle size of the nano zine oxide is 70nm.
A kind of preparation method of natural nano acne-removing composition, step include:
(1) preparation just mixes object: pressing load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, sea
Algae extract is uniformly mixed, and addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, bone
Board grass, preliminary coarse crushing are crushed using micronizer later, with 600 meshes after crushed, obtain the powder mixing of Chinese herbal medicine
Object is added Chinese medicine composition remaining ingredient, rare earth compound and nano zine oxide, ultramicro-vibration pulverizer is reused, after crushing
Cross 1800 meshes；Nanometer pulverization is finally carried out using the shearing ultra-fine grinding instrument of high speed centrifugation and obtains nanoscale load rare earth element
Traditional Chinese medicinal components；
(3) prepare natural nano acne-removing composition: by the traditional Chinese medicinal components of step (2) nanoscale load rare earth element be added to
(1) it just mixes in object, under the conditions of 90MPa pressure, 65 DEG C of temperature, carries out high pressure homogenizer and recycle homogeneous 15 times, naturally received
Rice acne-removing composition.
Comparative example 1
Difference from Example 5 is, 0 part of nano zine oxide.
Comparative example 2
Difference from Example 5 is, 0 part of cerium chloride, 0 part of nano zine oxide.
Comparative example 3
Difference from Example 5 is that the particle size of the nano zine oxide is 20nm.
Comparative example 4
Difference from Example 5 is that the particle size of the nano zine oxide is 350nm.
Comparative example 5
Difference from Example 5 is, 0 part of white Chinese rose extract.
Comparative example 6
Difference from Example 5 is, 0 part of tea tree extract.
Comparative example 7
Difference from Example 5 is, 0.015 part of tea tree extract.
Comparative example 8
Difference from Example 5 is, 10 parts of white Chinese rose extract.
Comparative example 9
Difference from Example 5 is that a kind of preparation method of natural nano acne-removing composition, step (3) is middle to be carried out
High pressure homogenizer recycles homogeneous 5 times.
Performance test
One, stability test
Test method: by embodiment 1-5, the obtained natural nano acne-removing composition of comparative example 1-9 as test object,
It is respectively placed in -20 DEG C, 25 DEG C and 45 DEG C of environment temperature, the physics shape of test object is observed after being respectively placed in one month
State.
Using it is non-discolouring, without Precipitation, free from extraneous odour as standard, test result: qualified；
There is the color of any appearance, has Precipitation, has the phenomenon that peculiar smell, test result: unqualified.
1 stability test result of table
Two, security test
It selects 100 volunteers of 18-45 one full year of life as test object, chooses at random, men and women is unlimited, Example 1-5, right
The obtained natural nano acne-removing composition of ratio 1-9 is applied to the hand of volunteer, the position of neck, face, adhere to using
It 7 days, uses 8 hours daily, follow-up observation volunteer is with the presence or absence of uncomfortable, itch, erythema, the abnormal conditions such as burn.
2 security test index of table
| Grade | Grade |
| Level-one is without any exception | 0 |
| Second level is very slight uncomfortable | 1 |
| Three-level is more uncomfortable | 2 |
| Level Four is clearly uncomfortable | 3 |
| Pyatyi is seriously uncomfortable | 4 |
Test result is as follows:
3 safety grades number of table
Three, performance test
1, the anti-adsorbing powder dust measure of merit of natural nano acne-removing composition: obtained by Example 1-5, comparative example 1-9
Natural nano acne-removing composition as experimental subjects, be uniformly applied on glass slide, each test object takes three groups, is exposed to
24 hours in outside air, after, it, can be with by without to being covered with glass slide using dust state on micro- sem observation glass slide
It is divided into 4 grades.
The anti-adsorbing powder dust test index of table 4
| Grade | Grade |
| Almost without dust | 1 |
| A small amount of dust | 2 |
| More apparent dust | 3 |
The anti-adsorbing powder dust test result of table 5
2, it the cure rate test of acne flesh: selects 500 small pox flesh volunteers of 18-40 one full year of life as test object, arbitrarily selects
It selects, men and women is unlimited, the obtained natural nano acne-removing composition of Example 1-5, comparative example 1-9, is applied to volunteer's face
Position, adhere to using 3 days, smeared twice using early, evening daily, summarize volunteer's acne cure rate, cure rate=healing will
Hope person/volunteer's number × 100%；Volunteer adheres to whether follow-up observation acne scar had the phenomenon that desalination, elimination using 21 days,
There is apparent volunteer's number/volunteer's number × 100% of acne scar=acne scar, no acne scar=face is without the remaining volunteer of pockmark
Number/volunteer's number × 100%；It is stopped using after 21 days, tracks whether investigation and interview has with the presence or absence of acne acne after half a year
The phenomenon that recurrence, summarizes and calculates recurrence rate, recurrence rate=recurrence volunteer number/volunteer's number × 100%.
The cure rate of 6 acne flesh of table, goes acne scar the performance test results at recurrence rate
| Skin condition | Cure rate | Recurrence rate | There is acne scar | Without acne scar |
| Embodiment 1 | 97% | 4% | 13% | 87% |
| Embodiment 2 | 96% | 3% | 8% | 92% |
| Embodiment 3 | 98% | 3% | 11% | 89% |
| Embodiment 4 | 98% | 1% | 9% | 91% |
| Embodiment 5 | 99% | 0% | 3% | 97% |
| Comparative example 1 | 91% | 10% | 16% | 84% |
| Comparative example 2 | 90% | 11% | 30% | 70% |
| Comparative example 3 | 93% | 8% | 21% | 79% |
| Comparative example 4 | 85% | 10% | 25% | 75% |
| Comparative example 5 | 92% | 11% | 17% | 83% |
| Comparative example 6 | 86% | 13% | 19% | 81% |
| Comparative example 7 | 91% | 7% | 16% | 84% |
| Comparative example 8 | 91% | 9% | 17% | 83% |
| Comparative example 9 | 84% | 12% | 19% | 81% |
Claims (10)
1. a kind of natural nano acne-removing composition, which is characterized in that according to parts by weight, raw material includes at least: Chinese medicine composition
1-5 parts, 0.01-0.5 parts of rare earth compound, 0.01~0.25 part of nano zine oxide, 1-10 parts of tea tree extract, the extraction of white Chinese rose
1-20 parts of object, 2-8 parts of aloe extract, 2-10 parts of vitamin, 2-8 parts of marine algae extract, 30-60 parts of glycerol.
2. a kind of natural nano acne-removing composition according to claim 1, which is characterized in that the Chinese medicine composition, dilute
Weight ratio between earth compounds, nano zine oxide is 1:(0.01~0.1): (0.01~0.05).
3. a kind of natural nano acne-removing composition according to claim 1, which is characterized in that the raw materials of traditional Chinese medicine composition
By weight, comprising yunnan euonymus root and stem 0.005-0.5 parts, 0.5-1 parts of Radix Glycyrrhizae, 0.5-1 parts of Astragalus Root P.E, 1-2 parts of white lilac,
0.1-2 parts of Paris polyphylla, 0.1-1 parts of Leonurus extract, 1-2 parts of mung bean flour, 0.5-1 parts of fortune paulownia flower, 0.5-2 parts of wormwood, Radix Angelicae Sinensis
0.1-1 parts, 0.1-2 parts of Lepisorus thunbergianus (Kaulf.) Ching.
4. a kind of natural nano acne-removing composition according to claim 3, which is characterized in that the rare earth compound and gold
The weight ratio of silk Cortex Eucommiae is 1:(0.5~1).
5. a kind of natural nano acne-removing composition according to claim 1, which is characterized in that the rare earth compound is chlorine
Change rare earth and/or rare earth oxide.
6. a kind of natural nano acne-removing composition according to claim 5, which is characterized in that the rare earth chloride is chlorination
Lanthanum and/or cerium chloride；The rare earth oxide is cerium oxide and/or lanthana.
7. a kind of natural nano acne-removing composition according to claim 1, which is characterized in that the tea tree extract and white
The weight ratio of Chinese rose extract is 1:(1~2).
8. a kind of natural nano acne-removing composition according to claim 1, which is characterized in that the nano zine oxide is received
Grain of rice diameter is 45nm~100nm.
9. a kind of preparation method of natural nano acne-removing composition according to claim 3, which is characterized in that step is at least
Include:
(1) preparation just mixes object: mentioning by load weighted tea tree extract, white Chinese rose extract, aloe extract, vitamin, seaweed
Object is taken, is uniformly mixed, addition is sufficiently mixed uniformly into glycerol, obtains just mixed object；
(2) it prepares the Chinese medicine of nanoscale load rare earth element: weighing yunnan euonymus root and stem, Radix Glycyrrhizae, fortune paulownia flower, wormwood, Radix Angelicae Sinensis, dominoes
Grass, preliminary coarse crushing, is crushed using micronizer later, with 400~800 meshes after crushed, obtains the powder of Chinese herbal medicine
Mixture is added Chinese medicine composition remaining ingredient, rare earth compound and nano zine oxide, reuses ultramicro-vibration pulverizer, powder
1500~2000 meshes are crossed after broken；It is negative that nanometer pulverization acquisition nanoscale is finally carried out using the shearing ultra-fine grinding instrument of high speed centrifugation
Carry the traditional Chinese medicinal components of rare earth element；
(3) it prepares natural nano acne-removing composition: the traditional Chinese medicinal components of step (2) nanoscale load rare earth element is added to (1)
Just in mixed object, under the conditions of 80~100MPa pressure, 60~70 DEG C of temperature, carries out high pressure homogenizer and recycles homogeneous 10~20 times,
Obtain natural nano acne-removing composition.
10. a kind of natural nano acne-removing composition according to claim 1 is applied to cosmetic field.
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|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: 310000 Room 608, floor 6, building 4, Haizhi center, 2301 yuhangtang Road, Cangqian street, Yuhang District, Hangzhou City, Zhejiang Province Applicant after: Zhejiang shiweikang Technology Group Co., Ltd Applicant after: Zhejiang shiweikang Medical Technology Co., Ltd Address before: 311100 608, 6 floor, 4 tower, Hai Chi Centre, 2301 Yuhang Tang Road, Yuhang District, Hangzhou, Zhejiang. Applicant before: ZHEJIANG SHIWEIKANG TECHNOLOGY Co.,Ltd. Applicant before: ZHEJIANG AIKA MEDICAL TECHNOLOGY Co.,Ltd. |
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| CB02 | Change of applicant information | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20210226 Address after: 321000 Lanxi Economic Development Zone, Jinhua City, Zhejiang Province (No. 435, Yanzhou Road, Lanjiang Street) (self declaration) Applicant after: Zhejiang shiweikang biomedical materials Co.,Ltd. Address before: Room 608, 6th floor, building 4, Haizhi center, 2301 yuhangtang Road, Cangqian street, Yuhang District, Hangzhou City, Zhejiang Province 310000 Applicant before: Zhejiang shiweikang Technology Group Co.,Ltd. Applicant before: Zhejiang shiweikang Medical Technology Co.,Ltd. |
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| TA01 | Transfer of patent application right | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181207 |
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| RJ01 | Rejection of invention patent application after publication |