CN108904729A - It is a kind of to treat infertile Chinese medicinal composition preparation and preparation method thereof - Google Patents
It is a kind of to treat infertile Chinese medicinal composition preparation and preparation method thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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Abstract
Infertile Chinese medicinal composition preparation is treated the invention discloses a kind of, the Chinese herbal medicine including following parts by weight：300~500 parts of radix paeoniae rubra, 250~450 parts of philippine flemingia root, 100~300 parts of myrrh, 300~500 parts of field pennycress, 250~420 parts of spina gleditsiae, 300~500 parts of Fructus Liquidambaris, impetuous 100~300 parts, 300~500 parts of the dried immature fruit of citron orange, 100~300 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 200~400 parts of semen coicis, 300~500 parts of rhizoma alismatis.The important composition preparation can effectively treat gynaecological imflammation and infertility, and therapeutic effect is good and without side-effects.
Description
Technical field
It is the present invention relates to the technical field of medicine production, in particular to a kind of to treat infertile Chinese medicinal composition preparation
And preparation method thereof.
Background technique
Fertility is the required of race's procreation, evolution and human development.According to document announcement, nowadays 10%~15% reproduction age husband
Woman cannot give birth to for various reasons, and with the development of society, people life style and living environment great variety,
Such as rhythm of life is accelerated, and stress increases, increasing environmental pollution etc., cannot give birth to phenomenon and the trend increased is presented.In
Doctor thinks that infertile illness is related with the shape deficiency of vital energy reality of men and women, essence and blood prosperity and decline,《Traditional Chinese medical science guide》Point out that " man is to protect
Based on essence, woman is based on menstruation regulating, vital essence foot, through water tune, without must not have sub- person ".Infertility is a kind of common disease of women,
Wedding matrimonial cohabitation 3 years, there is normal sexuality, unused contraceptive device, and is never pregnant, that is, can be described as infertility.Modern medicine is recognized
It is more complex for this disease cause of disease but clinical with endocrine disturbance, such as ovarian dysfunction, inadequate luteal function and genital diseases,
Such as fallopian tubal is lacked of proper care, inadequate luteal function and genital diseases, and salpingitis tubal, genital tuberculosis etc. are common.And
Traditional medicine think with asthenia of renal qi, insufficiency of vital energy and blood, stagnation of liver qi, phlegm stagnation, influence Chong and Ren channel disorder, cannot be fertilized into pregnant has
It closes.Therefore need to find the prescription for effectively solving the problems, such as female infertility.
Summary of the invention
It is an object of the invention to：In view of the above problems, gynaecological imflammation and infertile can effectively be treated by providing one kind
Chinese medicinal composition preparation of sterility and preparation method thereof.
In order to achieve the above-mentioned object of the invention, the technical solution adopted by the present invention is as follows：
It is a kind of to treat infertile Chinese medicinal composition preparation, the Chinese herbal medicine including following parts by weight：Radix paeoniae rubra 300~
500 parts, 250~450 parts of philippine flemingia root, 100~300 parts of myrrh, 300~500 parts of field pennycress, 250~420 parts of spina gleditsiae, Lu Lu
300~500 parts logical, impetuous 100~300 parts, 300~500 parts of the dried immature fruit of citron orange, 100~300 parts of stir-baked RADIX PHYTOLACCAE with vinegar, semen coicis 200~400
Part, 300~500 parts of rhizoma alismatis.
Preferably, which includes the Chinese herbal medicine of following parts by weight：350~450 parts of radix paeoniae rubra, philippine flemingia root
300~400 parts, 160~250 parts of myrrh, 350~450 parts of field pennycress, 300~400 parts of spina gleditsiae, 360~450 parts of Fructus Liquidambaris,
160~250 parts impetuous, 350~450 parts of the dried immature fruit of citron orange, 150~250 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 270~350 parts of semen coicis, rhizoma alismatis 360~
450 parts.
Preferably, which includes the Chinese herbal medicine of following parts by weight：400~420 parts of radix paeoniae rubra, philippine flemingia root
320~360 parts, 200~220 parts of myrrh, 400~430 parts of field pennycress, 320~350 parts of spina gleditsiae, 400~430 parts of Fructus Liquidambaris,
180~220 parts impetuous, 400~430 parts of the dried immature fruit of citron orange, 190~220 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 300~340 parts of semen coicis, rhizoma alismatis 400~
430 parts.
Preferably, the preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds water, carry out after once decocting, by one
Secondary decocting liquid filtering is poured out, and is added the water of equivalent, is carried out secondary decoction filtering and obtain secondary decocting liquid；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated into appropriate close
It is spare to form thick paste for degree；
(3) starch is added in the thick paste in step (2), and after mixed at high speed is uniform, decompression is sufficiently dried, crushed into small
Grain；
(4) little particle in step (3) is added talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
Preferably, in step (1), the amount of water is 8~12 times of raw material volume, and the primary decoction is decocted with secondary
The decocting time boiled is 1.5~4h.
Preferably, in step (2), the filtrate, which is concentrated by, boils evaporation and concentration, the density appropriate for filtrate
For 1.25~1.28g/cm3。
Preferably, in step (3), the amount of the starch is 30~70 parts, and described be dried under reduced pressure is by vacuumizing shape
60~80 DEG C of dryings are warming up at negative pressure.
Preferably, in step (4), the amount of the talcum powder is 15~30 parts.
Traditional Chinese Medicine thinks that female sterility is not filled by native endowment deficiency, sexual overstrain, kidney essense mostly, rushes conception vessel void or kidney
Asthenic yin, uterus void is cold or ferritic is weak, deficiency of YIN-blood, vessels of the uterus dystrophy；Or feelings will is unsmooth, stagnation of liver qi is qi-blood disharmony；Or
Ferritic is fat, throws off restraint food greasy and surfeit flavour, and the insufficiency of both the spleen and the kindey accumulates raw phlegm wet, and mechanism of qi retardance, punching is appointed obstructed；Or blood stasis condensation, abdominal mass product
Poly-, product causes in born of the same parents are medium.And blood stasis stagnation is one of this disease most common reason.Since blood stasis is stagnated, punching, which is appointed, owes logical, and the sea of blood is not
Energy spill-over as scheduled, therefore often have delayed menstrual cycle.Since blood resistance is in uterus, sea of blood disorder of qi, menses operation is unsmooth, therefore has small through row
Abdomen pain with tenderness, or it is less through measuring, and leaching drip is unsmooth；It is black to be carried out color purple, accompanies clot, it is for gas that tongue, which has purple point, and pulse condition string is puckery
Machine is unsmooth, hemostasis stagnate uterus as.Caused by this disease is both stagnated for blood stasis, when with activating microcirculation and removing stasis medicinal, clearing and activating the channels and collaterals is method.
We are to stagnate caused female acyesis for blood stasis and set, using radix paeoniae rubra, philippine flemingia root as monarch drug in a prescription；With myrrh, field pennycress,
Spina gleditsiae, Fructus Liquidambaris are ministerial drug；Using the seed of garden balsam, the dried immature fruit of citron orange, stir-baked RADIX PHYTOLACCAE with vinegar, semen coicis, rhizoma alismatis as adjutant, altogether at activating microcirculation and removing stasis medicinal, promoting menstruation
Active agent.Radix paeoniae rubra bitter in side, cold nature, return liver warp.There is the effect of stasis-dispelling and pain-killing, blood circulation, philippine flemingia root is sweet in flavor, and it is pungent,
It is warm-natured.There is the effect of dispersing blood stasis detoxifies and fills blood, stasis eliminatings are long-pending.It is altogether monarch drug in a prescription with radix paeoniae rubra.Myrrh bitter, it is mild-natured.Return heart, liver, spleen
Through, have the effect of promoting blood circulation and stopping pain, detumescence and promoting granulation.Field pennycress acrid flavour, bitter, cold nature.Return stomach, large intestine, Liver Channel, be usually used in stasis it
Chest and abdomen pain, can stasis-dispelling and pain-killing.Spina gleditsiae acrid flavour, it is warm-natured, there is promoting blood circulation effect.Fructus Liquidambaris bitter, it is mild-natured to have dispelling wind and removing obstruction in the meridians
Effect, is ministerial drug with myrrh, field pennycress, spina gleditsiae altogether, assists radix paeoniae rubra, philippine flemingia root activating microcirculation and removing stasis medicinal, clearing and activating the channels and collaterals.Adjutant has acute
Son, the dried immature fruit of citron orange, stir-baked RADIX PHYTOLACCAE with vinegar, semen coicis, rhizoma alismatis.Impetuous bitter, it is pungent, it is warm-natured, there are blood-breaking, disperse accumulation, softening hard masses effect.Dried immature fruit of citron orange bitter,
It is pungent, cold nature.Returns spleen, stomach, large intestine channel, can relieving stagnant Qi disperse accumulation, resolving sputum remove ruffian.Stir-baked RADIX PHYTOLACCAE with vinegar bitter, cold in nature, return lung, kidney, large intestine channel,
Xia Lishui is rushed down, it can dispersing swelling and dissipating binds.Semen coicis is sweet in flavor, light, cold nature, returns spleen, stomach, lung channel, there is clearing damp and promoting diuresis, invigorating the spleen, and eliminating impediment is made
With.Rhizoma alismatis is sweet in flavor, light, cold in nature, returns kidney, bladder meridian, there is clearing damp and promoting diuresis, the effect of expelling the heat-evil.The dried immature fruit of citron orange, stir-baked RADIX PHYTOLACCAE with vinegar, semen coicis, rhizoma alismatis four
Medicine is all cold, can break through philippine flemingia root, the seed of garden balsam, spina gleditsiae temperate-dryness.All medicines share, altogether at activating microcirculation and removing stasis medicinal, the agent of clearing and activating the channels and collaterals,
Female acyesis caused by being stagnated for blood stasis.
In conclusion by adopting the above-described technical solution, having the advantages that：
(1) present invention is by using radix paeoniae rubra, philippine flemingia root as monarch drug in a prescription；Using myrrh, field pennycress, spina gleditsiae, Fructus Liquidambaris as ministerial drug；With
The seed of garden balsam, the dried immature fruit of citron orange, stir-baked RADIX PHYTOLACCAE with vinegar, semen coicis, rhizoma alismatis are adjutant, altogether at activating microcirculation and removing stasis medicinal, the agent of clearing and activating the channels and collaterals, treatment gynaecological imflammation and
Infertile effect is good and without side-effects, wide application of the crowd.
(2) preparation method in the present invention is mentioned by using water twice and then concentration addition starch is prepared into particle and is made again
Capsule, entire process flow it is easy to operate.
(3) there is good activating microcirculation and removing stasis medicinal, the effect of clearing and activating the channels and collaterals using the capsule that formula and method of the invention are prepared into
Fruit, the effective percentage for curing gynaecological imflammation are up to 95.3%, and the effective percentage for curing infertility is up to 82.1%.
Specific embodiment
To make the objectives, technical solutions, and advantages of the present invention more comprehensible, preferred embodiment is enumerated below, to this hair
Bright further description.However, it is necessary to illustrate, many details listed in specification are used for the purpose of making reader to this
The one or more aspects of invention have a thorough explanation, also may be implemented even without these specific details of the invention
These aspects.
Embodiment 1
It is a kind of to treat infertile Chinese medicinal composition preparation, the Chinese herbal medicine including following parts by weight：300 parts of radix paeoniae rubra,
250 parts of philippine flemingia root, 100 parts of myrrh, 300 parts of field pennycress, 250 parts of spina gleditsiae, 300 parts of Fructus Liquidambaris, impetuous 100 parts, the dried immature fruit of citron orange 300
Part, 100 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 200 parts of semen coicis, 300 parts of rhizoma alismatis.
The preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds 8 times of water, once decocted
After 1.5h, a decocting liquid filtering is poured out, 8 times of water is added, secondary decoction 1.5h is carried out and secondary decocting liquid is obtained by filtration；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated by evaporation to density
For 1.25g/cm3, it is spare to form thick paste；
(3) thick paste in step (2) is added 30 parts of starch, after mixed at high speed is uniform, decompression by vacuumize to be formed it is negative
Pressure is warming up to 60 DEG C and is dried, crushed into little particle；
(4) little particle in step (3) is added 15 parts of talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
Embodiment 2
It is a kind of to treat infertile Chinese medicinal composition preparation, the Chinese herbal medicine including following parts by weight：500 parts of radix paeoniae rubra,
450 parts of philippine flemingia root, 300 parts of myrrh, 500 parts of field pennycress, 420 parts of spina gleditsiae, 500 parts of Fructus Liquidambaris, impetuous 300 parts, the dried immature fruit of citron orange 500
Part, 300 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 400 parts of semen coicis, 500 parts of rhizoma alismatis.
The preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds 12 times of water, carry out primary decoction 4h
Afterwards, a decocting liquid filtering is poured out, adds 12 times of water, carried out secondary decoction 4h and secondary decocting liquid is obtained by filtration；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated by evaporation to appropriate
Density 1.28g/cm3, it is spare to form thick paste；
(3) thick paste in step (2) is added 70 parts of starch, after mixed at high speed is uniform, decompression by vacuumize to be formed it is negative
Pressure is warming up to 80 DEG C and is dried, crushed into little particle；
(4) little particle in step (3) is added 30 parts of talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
Embodiment 3
It is a kind of to treat infertile Chinese medicinal composition preparation, the Chinese herbal medicine including following parts by weight：350 parts of radix paeoniae rubra,
300 parts of philippine flemingia root, 160 parts of myrrh, 350 parts of field pennycress, 300 parts of spina gleditsiae, 360 parts of Fructus Liquidambaris, impetuous 160 parts, the dried immature fruit of citron orange 350
Part, 150 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 270 parts of semen coicis, 360 parts of rhizoma alismatis.
The preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds 10 times of water, carry out primary decoction 2h
Afterwards, a decocting liquid filtering is poured out, adds 10 times of water, carried out secondary decoction 2h and secondary decocting liquid is obtained by filtration；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated by evaporation to appropriate
Density 1.25g/cm3, it is spare to form thick paste；
(3) thick paste in step (2) is added 50 parts of starch, after mixed at high speed is uniform, decompression by vacuumize to be formed it is negative
Pressure is warming up to 70 DEG C and is dried, crushed into little particle；
(4) little particle in step (3) is added 20 parts of talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
Embodiment 4
It is a kind of to treat infertile Chinese medicinal composition preparation, the Chinese herbal medicine including following parts by weight：450 parts of radix paeoniae rubra,
400 parts of philippine flemingia root, 250 parts of myrrh, 450 parts of field pennycress, 400 parts of spina gleditsiae, 450 parts of Fructus Liquidambaris, impetuous 250 parts, the dried immature fruit of citron orange 450
Part, 150~250 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 350 parts of semen coicis, 450 parts of rhizoma alismatis.
The preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds 10 times of water, carry out primary decoction 3h
Afterwards, a decocting liquid filtering is poured out, adds 10 times of water, carried out secondary decoction 3h and secondary decocting liquid is obtained by filtration；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated by evaporation to appropriate
Density 1.28g/cm3, it is spare to form thick paste；
(3) thick paste in step (2) is added 50 parts of starch, after mixed at high speed is uniform, decompression by vacuumize to be formed it is negative
Pressure is warming up to 80 DEG C and is dried, crushed into little particle；
(4) little particle in step (3) is added 25 parts of talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
Embodiment 5
It is a kind of to treat infertile Chinese medicinal composition preparation, the Chinese herbal medicine including following parts by weight：400 parts of radix paeoniae rubra,
320 parts of philippine flemingia root, 200 parts of myrrh, 400 parts of field pennycress, 320 parts of spina gleditsiae, 400 parts of Fructus Liquidambaris, impetuous 180 parts, the dried immature fruit of citron orange 400
Part, 190~220 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 300 parts of semen coicis, 400 parts of rhizoma alismatis.
The preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds 10 times of water, carry out primary decoction 3h
Afterwards, a decocting liquid filtering is poured out, adds 10 times of water, carried out secondary decoction 3h and secondary decocting liquid is obtained by filtration；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated by evaporation to appropriate
Density 1.28g/cm3, it is spare to form thick paste；
(3) thick paste in step (2) is added 60 parts of starch, after mixed at high speed is uniform, decompression by vacuumize to be formed it is negative
Pressure is warming up to 80 DEG C and is dried, crushed into little particle；
(4) little particle in step (3) is added 20 parts of talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
Embodiment 6
It is a kind of to treat infertile Chinese medicinal composition preparation, the Chinese herbal medicine including following parts by weight：420 parts of radix paeoniae rubra,
360 parts of philippine flemingia root, 220 parts of myrrh, 430 parts of field pennycress, 350 parts of spina gleditsiae, 430 parts of Fructus Liquidambaris, impetuous 220 parts, the dried immature fruit of citron orange 430
Part, 220 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 340 parts of semen coicis, 430 parts of rhizoma alismatis.
The preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds 10 times of water, carry out primary decoction 2h
Afterwards, a decocting liquid filtering is poured out, adds 10 times of water, carried out secondary decoction 2h and secondary decocting liquid is obtained by filtration；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated by evaporation to appropriate
Density 1.28g/cm3, it is spare to form thick paste；
(3) thick paste in step (2) is added 50 parts of starch, after mixed at high speed is uniform, decompression by vacuumize to be formed it is negative
Pressure is warming up to 80 DEG C and is dried, crushed into little particle；
(4) little particle in step (3) is added 20 parts of talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
Embodiment 7
It is a kind of to treat infertile Chinese medicinal composition preparation, the Chinese herbal medicine including following parts by weight：417 parts of radix paeoniae rubra,
333 parts of philippine flemingia root, 208 parts of myrrh, 417 parts of field pennycress, 333 parts of spina gleditsiae, 417 parts of Fructus Liquidambaris, impetuous 208 parts, the dried immature fruit of citron orange 417
Part, 208 parts of stir-baked RADIX PHYTOLACCAE with vinegar, 333 parts of semen coicis, 417 parts of rhizoma alismatis.
The preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds 10 times of water, once decocted
After 2.5h, a decocting liquid filtering is poured out, 10 times of water is added, secondary decoction 2.5h is carried out and secondary decocting liquid is obtained by filtration；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated by evaporation to appropriate
Density 1.26g/cm3, it is spare to form thick paste；
(3) thick paste in step (2) is added 50 parts of starch, after mixed at high speed is uniform, decompression by vacuumize to be formed it is negative
Pressure is warming up to 80 DEG C and is dried, crushed into little particle；
(4) little particle in step (3) is added 25 parts of talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
Clinical trial is summarized
One, the gynaecological imflammations clinical trial such as pelvic inflammatory disease, adnexitis is summarized
1, basic document
The selection 212 non-pregnant or breast feeding women with pelvic inflammatory disease and adnexitis and its caused pelvic hydrops, year
Age, average age was 32 years old between 20~45 years old, excluded the congenital physiological defect and deformity of reproductive system；Exclusion is associated with
The serious diseases such as the heart, liver, kidney and hemopoietic system and allergic constitution person.
2, diagnostic criteria
(1) it cures：Symptom, sign and gynecologial examination restore normally, and B ultrasound prompt is normal without hydrops or attachment.
(2) effectively：Symptom disappears, and gynecologial examination has clear improvement, and B ultrasound reduces before prompting hydrops, attachment thickening relatively to treat
2/3。
(3) invalid：Without improvement, it is preceding without diminution that B ultrasound prompts hydrops, attachment thickening relatively to treat for symptom, sign and inspection.
3, treatment method
Daily 2 times, every time two.30 days are 1 course for the treatment of, and 2~3 courses for the treatment of are used in conjunction.Curative effect is counted after the course for the treatment of.It sees
The drug for not having to this disease of other treatment is required during examining.
4, therapeutic effect
By the treatment of 3 courses for the treatment of, clinical efficacy is shown in Table 1.
1 therapeutic effect of table
| Total number of persons | Healing/example | Effectively/example | In vain/example | Cure rate | Total effective rate | Inefficiency |
| 212 | 173 | 29 | 10 | 81.4% | 95.3% | 4.7% |
As it can be seen from table 1 the treatment by 3 courses for the treatment of, Chinese medicinal composition preparation of the invention is to pelvic inflammatory disease, adnexitis
The cure rate of equal gynaecological imflammations is up to 81.4%, total effective rate 95.3%, it is seen that the traditional chinese medicine composition of the invention and its preparation can be with
The effectively gynaecological imflammations such as treatment pelvic inflammatory disease, adnexitis, show the traditional chinese medicine composition of the invention and its preparation to pelvic cavity by clinical observation
The gynaecological imflammations such as inflammation, adnexitis have significant curative effect, and curative effect is rapid, and patient generally can feel obvious after 1 course for the treatment of of taking medicine
Mitigate or disappear, without side-effects to patient, clinic is taken securely and reliably.
Two, the clinical trial of infertility caused by salpingemphraxis is summarized
1, basic document
Selection 263 because salpingemphraxis caused by infertility women, the age between 22~48 years old, average age
It is 33 years old, excludes the congenital physiological defect and deformity of reproductive system；Exclude to merge intentionally, liver, kidney and hemopoietic system etc. it is serious
Disease and allergic constitution person.
2, diagnostic criteria
(1) it cures：The person of becoming pregnant in 2 years.
(2) effectively：Though not becoming pregnant, related symptom, sign and laboratory, which check, with this disease improvement.
(3) invalid：Symptom, sign and laboratory check without improvement.
3, treatment method
Daily 2 times, every time two.30 days are 1 course for the treatment of, and 2~3 courses for the treatment of are used in conjunction.Curative effect is counted after the course for the treatment of.It sees
The drug for not having to this disease of other treatment is required during examining.
4, therapeutic effect
By the treatment of 3 courses for the treatment of, clinical efficacy is shown in Table 2.
2 therapeutic effect of table
| Total number of persons | Healing/example | Effectively/example | In vain/example | Cure rate | Total effective rate | Inefficiency |
| 263 | 72 | 144 | 47 | 27.4% | 82.1% | 17.9% |
From table 2 it can be seen that the treatment by 3 courses for the treatment of, Chinese medicinal composition preparation of the invention leads salpingemphraxis
The cure rate of the infertility of cause is up to 27.4%, total effective rate 82.1%, it is seen that the traditional chinese medicine composition of the invention and its preparation can be with
Effectively infertility caused by treatment salpingemphraxis, shows the traditional chinese medicine composition of the invention and its preparation to defeated ovum by clinical observation
Infertility caused by pipe choking has significant curative effect, and curative effect is rapid, and without side-effects to patient, and clinic is taken securely and reliably.
Three, case
1, Korea Spro, female 32 years old, 5 years unpregnancies after marriage, goodwill as between spouses was good, and sexual life is normal, this human-shaped body develops no abnormality seen,
Patient main suit：Infertile for many years, underbelly pain, fixed pain, abdominal pain refusing to pressure, menstruation is abnormal, spiritlessness and weakness.Thin lingual fur arteries and veins is tight
String, disease belong to stagnation of blood stasis, check fallopian tube obstruction.The rules for the treatment of are with activating microcirculation and removing stasis medicinal, regulating qi-flowing for relieving pain dredging the channel.Take capsule of the present invention
After one course for the treatment of, disease amelioration, symptom is completely disappeared after continuing two courses for the treatment of of medication, a raw boy after 1 year.
2, Chen, female 30 years old, infertile seek medical advice everywhere had no resolution within 4 years after marriage, patient main suit：It gets married 4 years unpregnancies, eumenorrhea,
There are an ectopic pregnancy, left side salpingotomy before half a year, right side tubal occlusion takes one course for the treatment of of capsule of the invention
Afterwards, disease amelioration continues to have taken 2 and check back, and the discovery wife's side has been pregnant.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, without departing from the principle of the present invention, it can also make several improvements and retouch, these improvements and modifications are also answered
It is considered as protection scope of the present invention.
Claims (8)
1. a kind of treat infertile Chinese medicinal composition preparation, it is characterised in that：Chinese herbal medicine including following parts by weight：It is red
300~500 parts of Chinese herbaceous peony, 250~450 parts of philippine flemingia root, 100~300 parts of myrrh, 300~500 parts of field pennycress, spina gleditsiae 250~420
Part, 300~500 parts of Fructus Liquidambaris, impetuous 100~300 parts, 300~500 parts of the dried immature fruit of citron orange, 100~300 parts of stir-baked RADIX PHYTOLACCAE with vinegar, semen coicis
200~400 parts, 300~500 parts of rhizoma alismatis.
2. a kind of infertile Chinese medicinal composition preparation is treated according to claim 1, it is characterised in that：Including following
The Chinese herbal medicine of parts by weight：350~450 parts of radix paeoniae rubra, 300~400 parts of philippine flemingia root, 160~250 parts of myrrh, field pennycress 350~
450 parts, 300~400 parts of spina gleditsiae, 360~450 parts of Fructus Liquidambaris, impetuous 160~250 parts, 350~450 parts of the dried immature fruit of citron orange, vinegar quotient
150~250 parts of land, 270~350 parts of semen coicis, 360~450 parts of rhizoma alismatis.
3. a kind of infertile Chinese medicinal composition preparation is treated according to claim 2, it is characterised in that：Including following
The Chinese herbal medicine of parts by weight：400~420 parts of radix paeoniae rubra, 320~360 parts of philippine flemingia root, 200~220 parts of myrrh, field pennycress 400~
430 parts, 320~350 parts of spina gleditsiae, 400~430 parts of Fructus Liquidambaris, impetuous 180~220 parts, 400~430 parts of the dried immature fruit of citron orange, vinegar quotient
190~220 parts of land, 300~340 parts of semen coicis, 400~430 parts of rhizoma alismatis.
4. it is described in any one of claim 1 to 3 it is a kind of treat infertile Chinese medicinal composition preparation, feature exists
In：The preparation method of the Chinese medicinal composition preparation is as follows：
(1) it takes the raw material of corresponding parts by weight to be broken into powder, is mixed and adds water, carry out after once decocting, will once decoct
Liquid filtering is poured out, and is added the water of equivalent, is carried out secondary decoction filtering and obtain secondary decocting liquid；
(2) by step (1) a decocting liquid and secondary decocting liquid mix, then mixed filtrate is concentrated into density appropriate,
It is spare to form thick paste；
(3) starch is added in the thick paste in step (2), and after mixed at high speed is uniform, decompression is sufficiently dried, crushed into little particle；
(4) little particle in step (3) is added talcum powder and is sufficiently mixed, and is packed into capsule shape into capsule preparations.
5. a kind of infertile Chinese medicinal composition preparation is treated according to claim 4, it is characterised in that：In step
(1) in, the amount of water is 8~12 times of raw material volume, the decocting time of the primary decoction and secondary decoction is 1.5~
4h。
6. a kind of infertile Chinese medicinal composition preparation is treated according to claim 4, it is characterised in that：In step
(2) in, the filtrate, which is concentrated by, boils evaporation and concentration for filtrate, and the density appropriate is 1.25~1.28g/cm3。
7. a kind of infertile Chinese medicinal composition preparation is treated according to claim 4, it is characterised in that：In step
(3) in, the amount of the starch is 30~70 parts, it is described be dried under reduced pressure be by vacuumize to be formed negative pressure be warming up to 60~80 DEG C it is dry
It is dry.
8. a kind of infertile Chinese medicinal composition preparation is treated according to claim 4, it is characterised in that：In step
(4) in, the amount of the talcum powder is 15~30 parts.
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|---|---|---|---|---|
| WO2006002096A2 (en) * | 2004-06-18 | 2006-01-05 | Vivo Therapeutics, Inc. | Low doses of l-citrulline for treating diseases |
| CN108042681A (en) * | 2018-01-18 | 2018-05-18 | 吕更玉 | It is a kind of to treat infertile Chinese medicine composition and preparation method thereof |
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2018
- 2018-08-23 CN CN201810967929.XA patent/CN108904729A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006002096A2 (en) * | 2004-06-18 | 2006-01-05 | Vivo Therapeutics, Inc. | Low doses of l-citrulline for treating diseases |
| CN108042681A (en) * | 2018-01-18 | 2018-05-18 | 吕更玉 | It is a kind of to treat infertile Chinese medicine composition and preparation method thereof |
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